Reactive oxygen species and cell signaling in lung ischemia

Cell Signaling in Vascular Inflammation

Volumn , Issue , 2005, Pages 125-135

  Fisher, Aron B ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Ca2+ influx; cell proliferation; Endothelial cells; eNOS activation; KATP channel; mechanotransduction; NADPH; oxidase; shear stress; superoxide generation

Indexed keywords

EID: 84857379924     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1007/978-1-59259-909-7_13     Document Type: Chapter

References (59)

1. McCord, J. M. (1985) Oxygen-derived free radicals in postischemic tissue injury. N. Engl. J. Med. 312, 159-163.
2. Cross, C. E., Halliwell, B., Borish, E. T., et al. (1987) Oxygen radicals and human disease. Ann. Intern. Med. 107, 526-545.
3. Horgan, M. J., Lum, H., and Malik, A. B. (1989) Pulmonary edema after pulmonary artery occlusion and reperfusion. Am. Rev. Respir. Dis. 140, 1421-1428.
4. Bishop, M. J., Lamm, W., Guidotti, S. M., and Albert, R. K. (1992) Pulmonary artery occlusion is sufficient to increase pulmonary vascular permeability in rabbits. J. Appl. Physiol. 73, 272-275.
5. Murata, T., Nakazawa, H., Mori, I., Ohta, Y., and Yamabayashi, H. (1992) Reperfusion after a two-hour period of pulmonary artery occlusion causes pulmonary necrosis. Am. Rev. Respir. Dis. 146, 1048-1053.
6. Gilroy, R. J., Jr., Bhatte, M. J., Wickersham, N. E., Pou, N. A., Loyd, J. E., and Overholser, K. A. (1993) Postischemic hypoperfusion during unilateral lung reperfusion in vivo. Am. Rev. Respir. Dis. 147, 276-282.
7. Eppinger, M. J., Deeb, G. M., Bolling, S. F., and Ward, P. A. (1997) Mediators of ischemia-reperfusion injury of rat lung. Am. J. Pathol. 150, 1773-1784.
8. Johnson, R. L., Jr., Cassidy, S. S., Haynes, M., Reynolds, R. L., and Schulz, W. (1981) Microvascular injury distal to unilateral pulmonary artery occlusion. J. Appl. Physiol. 51, 845-851.
9. Barie, P. S., Hakim, T. S., and Malik, A. B. (1981) Effect of pulmonary artery occlusion and reperfusion on extravascular fluid accumulation. J. Appl. Physiol. 50, 102-106.
10. Ide, H., Ino, T., Hasegawa, T., and Matsumoto, H. (1990) The role of leukocyte depletion by in vivo use of leukocyte filter in lung preservation after warm ischemia. Angiology 41, 318-327.
11. Palazzo, R., Hamvas, A., Shuman, T., Kaiser, L., Cooper, J., and Schuster, D. P. (1992) Injury in nonischemic lung after unilateral pulmonary ischemia with reperfusion. J. Appl. Physiol. 72, 612-620.
12. Horiguchi, T. and Harada, Y. (1993) The effect of protease inhibitor on reperfusion injury after unilateral pulmonary ischemia. Transplantation 55, 254-258.
13. Bishop, M. J., Chi, E. Y., and Cheney, F. W., Jr. (1987) Lung reperfusion in dogs causes bilateral lung injury. J. Appl. Physiol. 63, 942-950.
14. Allison, R. C., Kyle, J., Adkins, W. K., Prasad, V. R., McCord, J. M., and Taylor, A. E. (1990) Effect of ischemia reperfusion or hypoxia reoxygenation on lung vascular permeability and resistance. J. Appl. Physiol. 69, 597-603.
15. Adkins, W. K. and Taylor, A. E. (1990) Role of xanthine oxidase and neutrophils in ischemia-reperfusion injury in rabbit lung. J. Appl. Physiol. 69, 2012-2018.
16. Zamora, C. A., Baron, D., and Heffner, J. E. (1991) Washed human platelets prevent ischemia-reperfusion edema in isolated rabbit lungs. J. Appl. Physiol. 70, 1075-1084.
17. Adkins, W. K., Barnard, J. W., May, S., Seibert, A. F., Haynes, J., and Taylor, A. E. (1992) Compounds that increase cAMP prevent ischemia-reperfusion pulmonary capillary injury. J. Appl. Physiol. 72, 492-497.
18. Fisher, P. W., Huang, Y. C., Kennedy, T. P., and Piantadosi, C. A. (1993) PO2-dependent hydroxyl radical production during ischemia-reperfusion lung injury. Am. J. Physiol. 265, L279-L285.
19. Becker, P. M., Pearse, D. B., Permutt, S., and Sylvester, J. T. (1992) Separate effects of ischemia and reperfusion on vascular permeability in ventilated ferret lungs. J. Appl. Physiol. 73, 2616-2622.
20. Kennedy, T. P., Rao, N. V., Hopkins, C., Pennington, L., Tolley, E., and Hoidal, J. R. (1989) Role of reactive oxygen species in reperfusion injury of the rabbit lung. J. Clin. Invest. 83, 1326-1335.
21. Ljungman, A. G., Grum, C. M., Deeb, G. M., Bolling, S. F., and Morganroth, M. L. (1991) Inhibition of cyclooxygenase metabolite production attenuates ischemia-reperfusion lung injury. Am. Rev. Respir. Dis. 143, 610-617.
22. Eckenhoff, R. G., Dodia, C., Tan, Z., and Fisher, A. B. (1992) Oxygen-dependent reperfusion injury in the isolated rat lung. J. Appl. Physiol. 72, 1454-1460.
23. Seibert, A. F., Thompson, W. J., Taylor, A., Wilborn, W. H., Barnard, J., and Haynes, J. (1992) Reversal of increased microvascular permeability associated with ischemia-reperfusion: Role of cAMP. J. Appl. Physiol. 72, 389-395.
24. Okuda, M., Furuhashi, K., Nakai, Y., and Muneyuki, M. (1993) Decrease of ischaemia-reperfusion related lung oedema by continuous ventilation and allopurinol in rat perfusion lung model. Scand. J. Clin. Lab. Invest. 53, 625-631.
25. Barnard, J. W., Seibert, A. F., Prasad, V. R., et al. (1994) Reversal of pulmonary capillary ischemia-reperfusion injury by rolipram, a cAMP phosphodiesterase inhibitor. J. Appl. Physiol. 77, 774-781.
26. Das, K. C. and Misra, H. P. (1994) Amelioration of postischemic reperfusion injury by antiarrhythmic drugs in isolated perfused rat lung. Environ. Health Perspect. 102 Suppl. 10, 117-121.
27. Hsu, K., Wang, D., Wu, S. Y., Shen, C. Y., and Chen, H. I. (1994) Ischemia-reperfusion lung injury attenuated by ATPMgCl2 in rats. J. Appl. Physiol. 76, 545-552.
28. Imai, T. and Fujita, T. (1994) Unilateral lung injury caused by ischemia without hypoxia in isolated rat lungs perfused with buffer solution. J. Lab. Clin. Med. 123, 830-836.
29. Reignier, J., Mazmanian, M., Detruit, H., et al. (1994) Reduction of ischemia-reperfusion injury by pentoxifylline in the isolated rat lung. Paris-Sud University Lung Transplantation Group. Am. J. Respir. Crit. Care Med. 150, 342-347.
30. Moore, T. M., Khimenko, P., Adkins, W. K., Miyasaka, M., and Taylor, A. E. (1995) Adhesion molecules contribute to ischemia and reperfusion-induced injury in the isolated rat lung. J. Appl. Physiol. 78, 2245-2252.
31. Jurmann, M. J., Dammenhayn, L., Schaefers, H. J., and Haverich, A. (1990) Pulmonary reperfusion injury: Evidence for oxygen-derived free radical mediated damage and effects of different free radical scavengers. Eur. J. Cardiothorac. Surg. 4, 665-670.
32. Ayene, I. S., al-Mehdi, A. B., and Fisher, A. B. (1993) Inhibition of lung tissue oxidation during ischemia/reperfusion by 2-mercaptopropionylglycine. Arch. Biochem. Biophys. 303, 307-312.
33. Haynes, J., Jr., Seibert, A., Bass, J. B., and Taylor, A. E. (1990) U74500A inhibition of oxidant-mediated lung injury. Am. J. Physiol. 259, H144-H148.
34. Takeyoshi, I., Iwanami, K., Kamoshita, N., et al. (2001) Effect of lazaroid U-74389G on pulmonary ischemiareperfusion injury in dogs. J. Invest. Surg. 14, 83-92.
35. Fisher, A. B., Dodia, C., Tan, Z. T., Ayene, I., and Eckenhoff, R. G. (1991) Oxygen-dependent lipid peroxidation during lung ischemia. J Clin. Invest. 88, 674-679.
36. Zhao, G., al-Mehdi, A. B., and Fisher, A. B. (1997) Anoxia-reoxygenation versus ischemia in isolated rat lungs. Am. J. Physiol. 273, L1112-L1117.
37. Al-Mehdi, A. B., Zhao, G., Dodia, C., et al. (1998) Endothelial NADPH oxidase as the source of oxidants in lungs exposed to ischemia or high K+. Circ. Res. 83, 730-737.
38. Song, C., Al-Mehdi, A. B., and Fisher, A. B. (2001) An immediate endothelial cell signaling response to lung ischemia. Am. J. Physiol. Lung Cell Mol. Physiol. 281, L993-L1000.
39. Al-Mehdi, A. B., Shuman, H., and Fisher, A. B. (1997) Intracellular generation of reactive oxygen species during nonhypoxic lung ischemia. Am. J. Physiol. 272, L294-L300.
40. Ayene, I. S., Dodia, C., and Fisher, A. B. (1992) Role of oxygen in oxidation of lipid and protein during ischemia/reperfusion in isolated perfused rat lung. Arch. Biochem. Biophys. 296, 183-189.
41. Midorikawa, J., Maehara, K., Yaoita, H., et al. (2001) Continuous observation of superoxide generation in an in-situ ischemia-reperfusion rat lung model. Jpn. Circ. J. 65, 207-212.
42. Lansman, J. B. (1988) Endothelial mechanosensors. Going with the flow. Nature 331, 481-482.
43. Riley, D. J., Rannels, D. E., Low, R. B., Jensen, L., and Jacobs, T. P. (1990) NHLBI Workshop Summary. Effect of physical forces on lung structure, function, and metabolism. Am. Rev. Respir. Dis. 142, 910-914.
44. Watson, P. A. (1991) Function follows form: Generation of intracellular signals by cell deformation. FASEB J. 5, 2013-2019.
45. Davies, P. F. and Tripathi, S. C. (1993) Mechanical stress mechanisms and the cell. An endothelial paradigm. Circ. Res. 72, 239-245.
46. Fisher, A. B., Chien, S., Barakat, A. I., and Nerem, R. M. (2001) Endothelial cellular response to altered shear stress. Am. J. Physiol. Lung Cell Mol. Physiol. 281, L529-L533.
47. Davies, P. F., Barbee, K. A., Volin, M. V., et al. (1997) Spatial relationships in early signaling events of flow-mediated endothelial mechanotransduction. Annu. Rev. Physiol. 59, 527-549.
48. Manevich, Y., Al-Mehdi, A., Muzykantov, V., and Fisher, A. B. (2001) Oxidative burst and NO generation as initial response to ischemia in flow-Adapted endothelial cells. Am. J. Physiol. Heart Circ. Physiol. 280, H2126-H2135.
49. DeLeo, F. R. and Quinn, M. T. (1996) Assembly of the phagocyte NADPH oxidase: Molecular interaction of oxidase proteins. J. Leukoc. Biol. 60, 677-691.
50. Babior, B. M., Lambeth, J. D., and Nauseef, W. (2002) The neutrophil NADPH oxidase. Arch. Biochem. Biophys. 397, 342-344.
51. Zulueta, J. J., Sawhney, R., Yu, F. S., Cote, C. C., and Hassoun, P. M. (1997) Intracellular generation of reactive oxygen species in endothelial cells exposed to anoxia-reoxygenation. Am. J. Physiol. 272, L897-L902.
52. Jones, S. A., O'Donnell, V. B., Wood, J. D., Broughton, J. P., Hughes, E. J., and Jones, O. T. (1996) Expression of phagocyte NADPH oxidase components in human endothelial cells. Am. J. Physiol. 271, H1626-H1634.
53. Babior, B. M. (2000) The NADPH oxidase of endothelial cells. IUBMB Life 50, 267-269.
54. Forman, H. J. and Torres, M. (2001) Signaling by the respiratory burst in macrophages. IUBMB Life 51, 365-371.
55. Wei, Z., Costa, K., Al-Mehdi, A. B., Dodia, C., Muzykantov, V., and Fisher, A. B. (1999) Simulated ischemia in flowadapted endothelial cells leads to generation of reactive oxygen species and cell signaling. Circ. Res. 85, 682-689.
56. Wei, Z., Al-Mehdi, A. B., and Fisher, A. B. (2001) Signaling pathway for nitric oxide generation with simulated ischemia in flow-Adapted endothelial cells. Am. J. Physiol. Heart Circ. Physiol. 281, H2226-H2232.
57. Al-Mehdi, A. B., Zhao, G., and Fisher, A. B. (1998) ATP-independent membrane depolarization with ischemia in the oxygen-ventilated isolated rat lung. Am. J. Respir. Cell Mol. Biol. 18, 653-661.
58. Chatterjee, S., Al-Mehdi, A. B., Levitan, I., Stevens, T., and Fisher, A. B. (2003) Shear stress increases expression of a KATP channel in rat and bovine pulmonary vascular endothelial cells. Am. J. Physiol. Cell Physiol. 285, C959-C967.
59. Al-Mehdi, A. B., Song, C., Tozawa, K., and Fisher, A. B. (2000) Ca2+- and phosphatidylinositol 3-kinase-dependent nitric oxide generation in lung endothelial cells in situ with ischemia. J. Biol. Chem. 275, 39,807-39,810.