Matrix metalloproteinases as therapeutic targets in protozoan parasitic infections

Pharmacology and Therapeutics

Volumn 133, Issue 3, 2012, Pages 257-279

  Geurts, Nathalie ^a   Opdenakker, Ghislain ^a   Van Den Steen, Philippe E ^a  

^a REGA INSTITUTE FOR MEDICAL RESEARCH   (Belgium)

Author keywords

Blood brain barrier; Cerebrospinal fluid; Inhibitor; Leishmaniasis; Malaria; Matrix metalloproteinases; Parasite; Toxoplasmosis; Trypanosomiasis

Indexed keywords

ANTIBIOTIC AGENT; ANTIINFLAMMATORY AGENT; ANTIVIRUS AGENT; GELATINASE A; GELATINASE B; INTERSTITIAL COLLAGENASE; MATRILYSIN; MATRIX METALLOPROTEINASE; MATRIX METALLOPROTEINASE INHIBITOR; NEUTROPHIL COLLAGENASE; STROMELYSIN; STROMELYSIN 2; STROMELYSIN 3; TETRACYCLINE; TISSUE INHIBITOR OF METALLOPROTEINASE;

AFRICAN TRYPANOSOMIASIS; BACTERIAL INFECTION; BLOOD BRAIN BARRIER; CATALYSIS; CHAGAS DISEASE; DRUG TARGETING; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME INHIBITION; HOST PARASITE INTERACTION; HOST RESISTANCE; HUMAN; INNATE IMMUNITY; LEISHMANIASIS; MALARIA; MOLECULARLY TARGETED THERAPY; NONHUMAN; PARASITE IMMUNITY; PARASITE VIRULENCE; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN MOTIF; PROTEIN TARGETING; PROTOZOAL INFECTION; REVIEW; SKIN LEISHMANIASIS; TOXOPLASMOSIS; VIRUS INFECTION;

ANIMALS; ANTIPROTOZOAL AGENTS; HUMANS; MATRIX METALLOPROTEINASES; PROTOZOAN INFECTIONS;

EID: 84856501706     PISSN: 01637258     EISSN: 1879016X     Source Type: Journal    
DOI: 10.1016/j.pharmthera.2011.11.008     Document Type: Review

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