Regulation of intestinal α-defensin activation by the metalloproteinase matrilysin in innate host defense

Science

Volumn 286, Issue 5437, 1999, Pages 113-117

  Wilson, Carole L ^a   Ouellette, Andre J ^a   Satchell, Donald P ^a   Ayabe, Tokiyoshi ^a   López Boado, Yolanda S ^a   Stratman, Jennifer L ^a   Hultgren, Scott J ^a   Matrisian, Lynn M ^a   Parks, William C ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

DEFENSIN; MATRILYSIN; METALLOPROTEINASE;

AMINO ACID SEQUENCE; ANIMAL TISSUE; ARTICLE; BACTERICIDAL ACTIVITY; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ANALYSIS; ENZYME REGULATION; HOST RESISTANCE; INTESTINE MUCOSA; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN PROCESSING; PROTEIN SYNTHESIS;

AMINO ACID SEQUENCE; ANIMALS; CATALYSIS; CYTOPLASMIC GRANULES; ESCHERICHIA COLI; ESCHERICHIA COLI INFECTIONS; FEMALE; HUMANS; IMMUNITY, MUCOSAL; IMMUNITY, NATURAL; INTESTINAL MUCOSA; INTESTINE, SMALL; MALE; MATRIX METALLOPROTEINASE 7; METALLOENDOPEPTIDASES; MICE; MOLECULAR SEQUENCE DATA; PANETH CELLS; PROTEIN PRECURSORS; RECOMBINANT FUSION PROTEINS; SALMONELLA TYPHIMURIUM; TISSUE EXTRACTS;

ANIMALIA;

EID: 0033214433     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.286.5437.113     Document Type: Article

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