Severe Plasmodium falciparum malaria is associated with circulating ultra-large von willebrand multimers and ADAMTS13 inhibition

PLoS Pathogens

Volumn 5, Issue 3, 2009, Pages

  Larkin, Deirdre ^a   De Laat, Bas ^b   Jenkins, P Vince ^a   Bunn, James ^c,d   Craig, Alister G ^d   Terraube, Virginie ^a   Preston, Roger J S ^a   Donkor, Cynthia ^d,e   Grau, George E ^f   Van Mourik, Jan A ^b   O'Donnell, James S ^a,g  

^a TRINITY COLLEGE DUBLIN   (Ireland)

^b College of Medicine ^*

^c UNIVERSITY OF MALAWI   (Malawi)

^d LIVERPOOL SCHOOL OF TROPICAL MEDICINE   (United Kingdom)

^e KOMFO ANOKYE TEACHING HOSPITAL   (Ghana)

^f UNIVERSITY OF SYDNEY   (Australia)

^g ST JAMES S HOSPITAL   (Ireland)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN; VON WILLEBRAND FACTOR; VON WILLEBRAND FACTOR CLEAVING PROTEINASE; ADAM PROTEIN; ADAMTS13 PROTEIN, HUMAN;

ARTICLE; BRAIN MALARIA; CHILD; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE SEVERITY; ENZYME ACTIVITY; ENZYME INHIBITION; GHANA; HUMAN; INFANT; MALARIA FALCIPARUM; PRESCHOOL CHILD; PROTEIN BLOOD LEVEL; PROTEIN FUNCTION; ENDOTHELIUM CELL; ENZYME LINKED IMMUNOSORBENT ASSAY; METABOLISM; PROTEIN MULTIMERIZATION;

PLASMODIUM FALCIPARUM;

ADAM PROTEINS; CHILD; CHILD, PRESCHOOL; ENDOTHELIAL CELLS; ENZYME-LINKED IMMUNOSORBENT ASSAY; HUMANS; INFANT; MALARIA, FALCIPARUM; PROTEIN MULTIMERIZATION; VON WILLEBRAND FACTOR;

EID: 85052278805     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1000349     Document Type: Article

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