Cerebrospinal fluid levels of MMP-2, 7, and 9 are elevated in association with human immunodeficiency virus dementia

Annals of Neurology

Volumn 46, Issue 3, 1999, Pages 391-398

  Conant, Katherine ^a,d   McArthur, Justin C ^a,b   Griffin, Diane E ^a,b   Sjulson, Lucas ^a   Wahl, Larry M ^c   Irani, David N ^a,b  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH   (United States)

^c NATIONAL INSTITUTE OF DENTAL AND CRANIOFACIAL RESEARCH   (United States)

^d JOHNS HOPKINS HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GELATINASE A; MATRILYSIN;

ARTICLE; CEREBROSPINAL FLUID ANALYSIS; CYTOKINE PRODUCTION; DEMENTIA; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IMMUNOBLOTTING; PRIORITY JOURNAL; PROTEIN DETERMINATION;

AIDS DEMENTIA COMPLEX; BLOTTING, WESTERN; CELLS, CULTURED; COLLAGENASES; ENZYME-LINKED IMMUNOSORBENT ASSAY; GELATINASES; HUMANS; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE 7; MATRIX METALLOPROTEINASE 9; METALLOENDOPEPTIDASES; PROSPECTIVE STUDIES;

EID: 0032881663     PISSN: 03645134     EISSN: None     Source Type: Journal    
DOI: 10.1002/1531-8249(199909)46:3<391::AID-ANA15>3.0.CO;2-0     Document Type: Article

References (61)

1. Hecht FM, Grant RM, Petropoulos CJ, et al. Sexual transmission of an HIV-1 variant resistant to multiple reversetranscriptase and protease inhibitors. N Engl J Med 1998;30: 307-311
2. Sacktor N, McArthur JC. Prospects for therapy of HIV-associated neurologic diseases. J Neurovirol 1997;3:89-101
3. Glass JD, Fedor HS, Wesselingh SL, McArthur JC. Immunocytochemical quantitation of human immunodeficiency virus in the brain: correlations with dementia. Ann Neurol 1995;38: 755-762
4. Griffin DE, Wesselingh SL, McArthur JC. Elevated central nervous system prostaglandins in human immunodeficiency virus-associated dementia. Ann Neurol 1994;35:592-597
5. Wesselingh SL, Power C, Glass JD, et al. Intracerebral cytokine messenger RNA expression in acquired immunodeficiency syndrome dementia. Ann Neurol 1993;33:576-582
6. Gartner S, Markovits P, Markovitz D, et al. The role of mononuclear phagocytes in HTLV-III/LAV infection. Science 1986; 233:215-219
7. Koenig S, Gendelman HE, Orenstein JM, et al. Detection of AIDS virus in macrophages in brain tissue from AIDS patients with encephalopathy. Science 1986;233:1089-1093
8. Watkins BA, Dorn HH, Kelly WB, et al. Specific tropism of HIV-1 for microglial cells in primary human brain cultures. Science 1990;249:549-553
9. Wiley C, Schrier R, Nelson J, et al. Cellular localization of human immunodeficiency virus infection within the brains of acquired immune deficiency syndrome patients. Proc Natl Acad Sci USA 1986;83:7089-7093
10. Perno CF, Newcomb FM, Davis DA, et al. Relative potency of protease inhibitors in monocytes/macrophages acutely and chronically infected with human immunodeficiency virus. J Infect Dis 1998;178:413-422
11. Epstein LG, Gendelman HE. Human immunodeficiency virus type-1 infection of the nervous system: pathogenetic mechanisms. Ann Neurol 1993;33:429-436
12. Giulian D, Vaca K, Noonan CA. Secretion of neurotoxins by mononuclear phagocytes infected with HIV-1. Science 1990; 250:1593-1596
13. Adamson DC, Wildemann B, Sasaki M, et al. Immunologic NO synthase: elevation in severe AIDS dementia and induction by HIV-1 gp41. Science 1996;274:1917-1921
14. Talley AK, Dewhurst S, Perry SW, et al. Tumor necrosis factor alpha-induced apoptosis in human neuronal cells: protection by the antioxidant N-acetyl cysteine and the genes bcl-2 and crm-A. Mol Cell Biol 1995;15:2359-2366
15. Magnuson DSK, Knudsen BE, Geiger JD, et al. Human immunodeficiency virus type 1 Tat activates non-N-methyl-D-aspartate excitatory amino acid receptors and causes neurotoxicity. Ann Neurol 1995;37:373-380
16. Brenneman DE, McCune SK, Mervis RF, Hill JM. gp120 as an etiologic agent for neuroAIDS: neurotoxicity and model systems. Adv Neuroimmunol 1994;4:157-165
17. Dreyer EB, Kaiser PK, Offermann JT, Lipton SA. HIV-1 coat protein neurotoxicity prevented by calcium channel antagonists. Science 1990;248:364-367
18. Sasseville VG, Newman WA, Lackner AA, et al. Elevated vascular cell adhesion molecule-1 in AIDS encephalitis induced by simian immunodeficiency virus. Am J Pathol 1992;141:1021-1030
19. Pulliam L, Gascon R, Stubblebine M, et al. Unique monocyte subset in patients with AIDS dementia. Lancet 1997;349:692-695
20. Conant K, Garzino-Demo A, Nath A, et al. Induction of monocyte chemoattractant protein-1 in HIV-1 Tat stimulated astrocytes and elevation in AIDS dementia. Proc Natl Acad Sci USA 1998;95:3117-3121
21. Kelder W, McArthur JC, Nance-Sproson T, et al. β-Chemokines MCP-1 and RANTES are increased in cerebrospinal fluid of patients with HIV-associated dementia. Ann Neurol 1998; 44:831-835
22. Cinque P, Vago L, Mengozzi M, et al. Elevated cerebrospinal fluid levels of monocyte chemotactic protein-1 correlate with HIV-1 encephalitis and local viral replication. AIDS 1998;12: 1327-1332
23. Schmidtmayerova H, Nottet HSLM, Nuovo G, et al. Human immunodeficiency virus type 1 infection alters chemokine beta expression in human monocytes: implications for recruitment of leukocytes into brain and lymph nodes. Proc Natl Acad Sci USA 1996;93:700-704
24. Weiss JM, Downie SA, Lyman WD, Berman JW. Astrocyte-derived monocyte-chemoattractant protein-1 directs the transmigration of leukocytes across a model of the human blood-brain barrier. J Immunol 1998;160:6898-6903
25. Buttner A, Mehraein P, Weis, S. Vascular changes in the cerebral cortex in HIV-1 infection. II. An immunohistochemical and lectinhistochemical investigation. Acta Neuropathol (Berl) 1996;92:35-41
26. Weis S, Haug H, Budka H. Vascular changes in the cerebral cortex in HIV-1 infection: I. A morphometric investigation by light and electron microscopy. Clin Neuropathol 1996;15:361-366
27. Power C, Kong P, Crawford TO, et al. Cerebral white matter changes in acquired immunodeficiency syndrome dementia: alterations of the blood-brain barrier. Ann Neurol 1993;34:339-350
28. Marshall DW, Brey RL, Butzin CA, et al. CSF changes in a longitudinal study of 124 neurologically normal HIV-1-infected U.S. Air Force personnel. J Acquir Immune Defic Syndr 1991; 4:777-781
29. McArthur JC, Nance Sproson TE, Griffin DE, et al. The diagnostic utility of elevation in cerebrospinal fluid beta2-microglobulinin HIV-1 dementia. Neurology 1992;42:1707-1712
30. Wee Yong V, Krekoski CA, Forsyth PA, et al. Matrix metalloproteinases and diseases of the CNS. Trends Neurosci 1998;21: 75-80
31. Wilson CA, Matrisian LM. Matrilysin: an epithelial matrix metalloproteinase with potentially novel functions. Int J Biochem Cell Biol 1996;28:123-136
32. Clements JM, Cossins JA, Wells GMA, et al. Matrix metalloproteinase expression during experimental autoimmune encephalomyelitis and effects of a combined matrix metalloproteinase and tumour necrosis factor-α inhibitor. J Neuroimmunol 1997; 74:885-894
33. Rosenberg GA, Navratil M. Metalloproteinase inhibition blocks edema in intracerebral hemorrhage in the rat. Neurology 1997; 48:921-926
34. Anthony DC, Miller KM, Fearn S, et al. Matrix metalloproteinase expression in an experimentally-induced DTH model of multiple sclerosis in the rat CNS. J Neuroimmunol 1998;87: 62-72
35. Rosenberg GA, Kornfeld M, Estrada E, et al. TIMP-2 reduces proteolytic opening of the blood-brain barrier by type IV collagenase. Brain Res 1992;576:203-207
36. Janssen RS, Cornblath DR, Epstein LG, et al. Nomenclature and research case definitions for neurological manifestations of human immunodeficiency type-1 (HIV-1) infection: report of a working group of the American Academy of Neurology AIDS Task Force. Neurology 1991;41:778-785
37. Kinoshira T, Sato H, Okada A, et al. TIMP-2 promotes activation of progelatinase A by membrane-type 1 matrix metalloproteinase immobilized on agarose beads. J Biol Chem 1998; 273:16098-16103
38. Yamamoto H, Itoh F, Hinoda Y, et al. Expression of matrilysin mRNA in colorectal adenomas and its induction by truncated fibronectin. Biochem Biophys Res Commun 1994;201:657-664
39. Gottschall PE, Deb S. Regulation of matrix metalloproteinase expression in astrocytes, microglia and neurons. Neuroimmunomodulation 1996;3:69-75
40. Apodaca G, Rutka JT, Bouhana K, et al. Expression of metalloproteinases and metalloproteinase inhibitors by fetal astrocytes and glioma cells. Cancer Res 1990;15:2322-2329
41. Umehara F, Okada Y, Fujimoto N, et al. Expression of matrix metalloproteinases and tissue inhibitors of metalloproteinases in HTLV-I-associated myelopathy. J Neuropathol Exp Neurol 1998;57:839-849
42. Maeda A, Sobel RA. Matrix metalloproteinases in the normal human central nervous system, microglial nodules and multiple sclerosis lesions. J Neuropathol Exp Neurol 1996;55:300-309
43. Gijbels K, Masure S, Carton H, Opdenakker G. Gelatinase in the cerebrospinal fluid of patients with multiple sclerosis and other inflammatory neurological disorders. J Neuroimmunol 1992;41:29-34
44. Rosenberg GA, Dencoff JE, Correa N, et al. Effect of steroids on CSF matrix metalloproteinases in multiple sclerosis: relation to blood brain barrier injury. Neurology 1996;46:1626-1632
45. Leppert D, Ford J, Stabler G, et al. Matrix metalloproteinase 9 (gelatinase B) is selectively elevated in CSF during relapses and stable phases of multiple sclerosis. Brain 1998;121:2327-2334
46. Sporer B, Paul R, Koedel U, et al. Presence of matrix metalloproteinase-9 activity in the cerebrospinal fluid of human immunodeficiency virus-infected patients. J Infect Dis 1998; 178:854-857
47. Stuve O, Chabot S, Jung SS, et al. Chemokine-enhanced migration of human peripheral blood mononuclear cells is antagonized by interferon beta-1b through an effect on matrix metalloproteinase-9. J Neuroimmunol 1997;80:38-46
48. Lafrenie RM, Wahl LM, Epstein JS, et al. Activation of monocytes by HIV-Tat treatment is mediated by cytokine expression. J Immunol 1997;15:4077-4083
49. Zhang Y, McCluskey K, Fuji K, Wahl LM. Differential regulation of monocyte matrix metalloproteinase and TIMP-1 production by TNFα, GM-CSF, and IL-1b through prostaglandin dependent and independent mechanisms. J Immunol 1998;161: 3071-3076
50. Chong YH, Seoh JY, Park HK. Increased activity of matrix metalloproteinase-2 in human glial and neuronal cell lines treated with HIV-1 gp41 peptides. J Mol Neurosci 1998;10: 129-141
51. Marshall DC, Wyss-Coray T, Abraham CR. Induction of matrix metalloproteinase-2 in human immunodeficiency virus-1 glycoprotein 120 transgenic mouse brains. Neurosci Lett 1998; 254:97-100
52. Turgeon VL, Lloyd ED, Wang S, et al. Thrombin perturbs neurite outgrowth and induces apoptotic cell death in enriched chick spinal motoneuron cultures through caspase activation. J Neurosci 1998;18:6882-6891
53. Turgeon VL, Houenou LJ. The role of thrombin-like (serine) proteases in the development, plasticity and pathology of the nervous system. Brain Res Rev 1997;25:85-95
54. Choi BH, Suzuki M, Taiseung K, et al. Protease nexin-1: localization in the human brain suggests a protective role against extravasated serine proteases. Am J Pathol 1990;137:741-747
55. Kadota E, Nonaka K, Karasuno M, et al. Neurotoxicity of serum components, comparison between CA1 and striatum. Acta Neurochir Suppl (Wien) 1997;70:141-143
56. Masliah E, Heaton RK, Marcotte TD, et al. Dendritic injury is a pathological substrate for human immunodeficiency virus related cognitive disorders. Ann Neurol 1997;42:963-972
57. Lander AD, Fujii DK, Reichardt LF. Purification of a factor that promotes neurite outgrowth: isolation of laminin and associated molecules. J Cell Biol 1985;101:898-913
58. Patton BL, Chiu AY, Sanes JR. Synaptic laminin prevents glial entry into the synaptic cleft. Nature 1998;393:698-701
59. Bozzo C, Bellomo G, Silengo L, et al. Soluble integrin ligands and growth factors independently rescue neuroblastoma cells from apoptosis under nonadherent conditions. Exp Cell Res 1997;237:326-337
60. DiStefano PS, Chelsea DM, Schick CM, McKelvy JF. Involvement of a metalloproteinase in low-affinity nerve growth factor receptor truncation: inhibition of truncation in vitro and in vivo. J Neurosci 1993;13:2405-2414
61. Schonbeck U, Mach F, Libby P. Generation of biologically active IL-1 beta by matrix metalloproteinases: a novel caspase-1-independent pathway of IL-1 beta processing. J Immunol 1998; 161:3340-3346