Gelatinase B modulates selective opening of the blood-brain barrier during inflammation

American Journal of Physiology - Regulatory Integrative and Comparative Physiology

Volumn 274, Issue 5 43-5, 1998, Pages

  Mun Bryce, Sheila ^a   Rosenberg, Gary A ^a  

^a UNIVERSITY OF NEW MEXICO SCHOOL OF MEDICINE   (United States)

Author keywords

Basal lamina; Lipopolysaccharide; Matrix metalloproteinases; Metalloproteinase inhibitor; Neuroinflammation

Indexed keywords

DEXTRAN; GELATINASE A; GELATINASE B; LIPOPOLYSACCHARIDE; MATRIX METALLOPROTEINASE INHIBITOR; SUCROSE; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLOOD BRAIN BARRIER; CONTROLLED STUDY; ENCEPHALITIS; ENZYME SYNTHESIS; MALE; MEMBRANE PERMEABILITY; NONHUMAN; PRIORITY JOURNAL; RAT;

EID: 0031831764     PISSN: 03636119     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpregu.1998.274.5.r1203     Document Type: Article

References (37)

1. Andersson, P. B., V. H. Perry, and S. Gordon. Intracerebral injection of proinflammatory cytokines or leukocyte chemotoxins induces minimal myelomonocytic cell recruitment to the parenchyma of the central nervous system. J. Exp. Med. 176: 255-259, 1992.
2. 3H]dextran. Exp. Neurol. 97: 686-696, 1987.
3. Arvin, B., L. F. Neville, F. C. Barone, and G. Z. Feuerstein. The role of inflammation and cytokines in brain injury. Neurosci. Biobehav. Rev. 20: 445-452, 1996.
4. Birkedal-Hansen, H., W. G. Moore, M. K. Bodden, L. J. Windsor, B. Birkedal-Hansen, A. DeCarlo, and J. A. Engler. Matrix metalloproteinases: a review. Crit. Rev. Oral Biol. Med. 4: 197-250, 1993.
5. Bradbury, M. W. The blood-brain barrier. Exp. Physiol. 78: 453-472, 1993.
6. Brenner, D. A., M. O'Hara, P. Angel, M. Chojkier, and M. Karin. Prolonged activation of jun and collagenase genes by tumour necrosis factor-alpha. Nature 337: 661-663, 1989.
7. Browner, M. F., W. W. Smith, and A. L. Castelhano. Matrilysin-inhibitor complexes: common themes among metalloproteases. Biochemistry 34: 6602-6610, 1995.
8. Claudio, L., J. A. Martiney, and C. F. Brosnan. Ultrastructural studies of the blood-retina barrier after exposure to interleukin-1 beta or tumor necrosis factor-alpha. Lab. Invest. 70: 850-861, 1994.
9. Gearing, A. J., P. Beckett, M. Christodoulou, M. Churchill, J. Clements, A. H. Davidson, A. H. Drummond, W. A. Galloway, R. Gilbert, J. L. Gordon, T. M. Leber, M. Mangan, K. Miller, P. Nayee, K. Owen, S. Patel, W. Thomas, G. Wells, L. M. Wood, and K. Woolley. Processing of tumour necrosis factor-alpha precursor by metalloproteinases. Nature 370: 555-557, 1994.
10. Gijbels, K., R. E. Galardy, and L. Steinman. Reversal of experimental autoimmune encephalomyelitis with a hydroxamate inhibitor of matrix metalloproteases. J. Clin. Invest. 94: 2177-2182, 1994.
11. Hardebo, J. E. A time study in rat on the opening and reclosure of the blood-brain barrier after hypertensive or hypertonic insult. Exp. Neurol. 70: 155-166, 1980.
12. Hershkoviz, R., L. Cahalon, D. Gilat, S. Miron, A. Miller, and O. Lider. Physically damaged extracellular matrix induces TNF-alpha secretion by interacting resting CD4+ T cells and macrophages. Scand. J. Immunol. 37: 111-115, 1993.
13. Hirano, A., T. Kawanami, and J. F. Llena. Electron microscopy of the blood-brain barrier in disease. Microsc. Res. Tech. 27: 543-556, 1994.
14. Kaya, M., L. Chang, A. Truong, and M. W. Brightman. Chemical induction of fenestrae in vessels of the blood-brain barrier. Exp. Neurol. 142: 6-13, 1996.
15. Keep, R. F., and J. Xiang. N-system amino acid transport at the blood-CSF barrier. J. Neurochem. 65: 2571-2576, 1995.
16. Lockhart, B. P., F. Hamedi-Sangsari, J. Vignon, A. Privat, and J. Vila. A N-methyl-D-aspartate receptor-mediated neurotoxic effect of aspartate-based hydroxamate compounds in rat primary neuronal cultures. Brain Res. 670: 313-316, 1995.
17. Lotan, M., and M. Schwartz. Cross talk between the immune system and the nervous system in response to injury: implications for regeneration. FASEB J. 8: 1026-1033, 1994.
18. Matrisian, L. M. Metalloproteinases and their inhibitors in matrix remodeling. Trends Genet. 6: 121-125, 1990.
19. Matyszak, M. K., and V. H. Perry. Demyelination in the central nervous system following a delayed-type hypersensitivity response to bacillus Calmette-Guerin. Neuroscience 64: 967-977, 1995.
20. Mayhan, W. G., and D. D. Heistad. Permeability of blood-brain barrier to various sized molecules. Am. J. Physiol. 248 (Heart Circ. Physiol. 17): H712-H718, 1985.
21. McGeehan, G. M., J. D. Becherer, R. C. Bast, Jr., C. M. Boyer, B. Champion, K. M. Connolly, J. G. Conway, P. Furdon, S. Karp, S. Kidao, A. B. McElroy, J. Nichols, K. M. Pryzwansky, F. Schoenen, L. Sekut, A. Truesdale, M. Verghese, J. Warner, and J. P. Ways. Regulation of tumour necrosis factor-alpha processing by a metalloproteinase inhibitor. Nature 370: 558-561, 1994.
22. Nag, S., D. M. Robertson, and H. B. Dinsdale. Quantitative estimate of pinocytosis in experimental acute hypertension. Acta Neuropathol. (Berl.) 46: 107-116, 1979.
23. Ohno, K., K. D. Pettigrew, and S. I. Rapoport. Lower limits of cerebrovascular permeability to nonelectrolytes in the conscious rat. Am. J. Physiol. 235 (Heart Circ. Physiol. 4): H299-H307, 1978.
24. Partridge, C. A., J. J. Jeffrey, and A. B. Malik. A 96-kDa gelatinase induced by TNF-alpha contributes to increased microvascular endothelial permeability. Am. J. Physiol. 265 (Lung Cell Mol. Physiol. 9): L438-L447, 1993.
25. Quagliarello, V., and W. M. Scheid. Bacterial meningitis: pathogenesis, pathophysiology, and progress. N. Engl. J. Med. 327: 864-872, 1992.
26. Risau, W., and H. Wolburg. Development of the blood-brain barrier. Trends Neurosci. 13: 174-178, 1990.
27. Rosenberg, G. A., J. E. Dencoff, P. G. McGuire, L. A. Liotta, and W. G. Stetler-Stevenson. Injury-induced 92-kDa gelatinase and urokinase expression in rat brain. Lab. Invest. 71: 417-422, 1994.
28. Rosenberg, G. A., E. Y. Estrada, J. E. Dencoff, and W. G. Stetler-Stevenson. Tumor necrosis factor-alpha-induced gelatinase B causes delayed opening of the blood-brain barrier: an expanded therapeutic window. Brain Res. 703: 151-155, 1995.
29. Rosenberg, G. A., M. Kornfeld, E. Estrada, R. O. Kelley, L. A. Liotta, and W. G. Stetler-Stevenson. TIMP-2 reduces proteolytic opening of blood-brain barrier by type IV collagenase. Brain Res. 576: 203-207, 1992.
30. Sharief, M. K., and E. J. Thompson. In vivo relationship of tumor necrosis factor-alpha to blood-brain barrier damage in patients with active multiple sclerosis. J. Neuroimmunol. 38: 27-33, 1992.
31. Stetler-Stevenson, W. G., H. C. Krutzsch, M. P. Wacher, I. M. K. Margulies, and L. A. Liotta. The activation of human type IV collagenase proenzyme. J. Biol. Chem. 264: 1353-1356, 1989.
32. Wang, X., X. Fu, P. D. Brown, M. J. Crimmin, and R. M. Hoffman. Matrix metalloproteinase inhibitor BB-94 (batimastat) inhibits human colon tumor growth and spread in a patient-like orthotopic model in nude mice. Cancer Res. 54: 4726-4728, 1994.
33. Wilhelm, S. M., I. E. Collier, B. L. Marmer, A. Z. Eisen, G. A. Grant, and G. I. Goldberg. SV40-transformed human lung fibroblasts secrete a 92-kDa type FV collagenase which is identical to that secreted by normal human macrophages. J. Biol. Chem. 264: 17213-17221, 1989.
34. Wispelwey, B., A. J. Lesse, E. J. Hansen, and W. M. Scheld. Haemophilus influenzae lipopolysaccharide-induced blood brain barrier permeability during experimental meningitis in the rat. J. Clin. Invest. 82: 1339-1346, 1988.
35. Xu, J., and E. A. Ling. Studies of the ultrastructure and permeability of the blood-brain barrier in the developing corpus callosum in postnatal rat brain using electron dense tracers. J. Anat. 184: 227-237, 1994.
36. Yurchenco, P. D., and J. C. Schittny. Molecular architecture of basement membranes. FASEB J. 4: 1577-1590, 1990.
37. Ziylan, Y. Z., P. J. Robinson, and S. I. Rapoport. Blood-brain barrier permeability to sucrose and dextran after osmotic opening. Am. J. Physiol. 247 (Regulatory Integrative Comp. Physiol. 16): R634-R638, 1984.