Synthetic Plasmodium-like hemozoin activates the immune response: A morphology - Function study

PLoS ONE

Volumn 4, Issue 9, 2009, Pages

  Jaramillo, Maritza ^a,c   Bellemare, Marie Josée ^a,b   Martel, Caroline ^a   Shio, Marina Tiemi ^c   Contreras, Ana Paulina ^a   Godbout, Marianne ^a   Roger, Michel ^d   Gaudreault, Eric ^e   Gosselin, Jean ^e   Bohle, D Scott ^b   Olivier, Martin ^a  

^a RESEARCH INSTITUTE OF THE MCGILL UNIVERSITY HEALTH CENTRE   (Canada)

^b MCGILL UNIVERSITY   (Canada)

^c MCGILL UNIVERSITY   (Canada)

^d CENTRE HOSPITALIER DE L UNIVERSITÉ DE MONTRÉAL   (Canada)

^e LAVAL UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; HEMOZOIN; INDUCIBLE NITRIC OXIDE SYNTHASE; MESSENGER RNA; HEMIN; HEMOPROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; CRYSTAL STRUCTURE; ELECTRON MICROSCOPY; HUMAN; HUMAN CELL; IMMUNE RESPONSE; IMMUNOPATHOLOGY; IMMUNOSTIMULATION; IN VITRO STUDY; IN VIVO STUDY; INFLAMMATION; MORPHOLOGY; MOUSE; NONHUMAN; PHYSICAL CHEMISTRY; PLASMODIUM FALCIPARUM; PROTEIN FUNCTION; PROTEIN INTERACTION; PROTEIN STRUCTURE; PROTEIN SYNTHESIS; ANIMAL; BIOLOGICAL MODEL; CATALYSIS; CELL LINE; CHEMISTRY; CRYSTALLIZATION; DRUG EFFECT; IMMUNE SYSTEM; METABOLISM; PLASMODIUM CHABAUDI; SCANNING ELECTRON MICROSCOPY; STRUCTURE ACTIVITY RELATION; TRANSGENIC MOUSE; X RAY DIFFRACTION;

ANIMALS; CATALYSIS; CELL LINE; CRYSTALLIZATION; HEMEPROTEINS; HEMIN; HUMANS; IMMUNE SYSTEM; MICE; MICE, TRANSGENIC; MICROSCOPY, ELECTRON, SCANNING; MODELS, BIOLOGICAL; PLASMODIUM CHABAUDI; STRUCTURE-ACTIVITY RELATIONSHIP; X-RAY DIFFRACTION;

EID: 70349146697     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0006957     Document Type: Article

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