Neutrophil gelatinase B potentiates interleukin-8 tenfold by aminoterminal processing, whereas it degrades CTAP-III, PF-4, and GRO-α and leaves RANTES and MCP-2 intact

Blood

Volumn 96, Issue 8, 2000, Pages 2673-2681

  Van Den Steen, Philippe E ^a   Proost, Paul ^a   Wuyts, Anja ^a   Van Damme, Jo ^a   Opdenakker, Ghislain ^a  

^a REGA INSTITUTE FOR MEDICAL RESEARCH   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

BETA THROMBOGLOBULIN; CHEMOKINE RECEPTOR; CHEMOKINE RECEPTOR CXCR1; GELATINASE B; INTERLEUKIN 8; MELANOMA GROWTH STIMULATORY ACTIVITY FACTOR; MONOCYTE CHEMOTACTIC PROTEIN 2; RANTES; STROMELYSIN; THROMBOCYTE FACTOR 4; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ARTICLE; BINDING COMPETITION; CALCIUM CELL LEVEL; ENZYME PURIFICATION; ENZYME REGULATION; HUMAN; HUMAN CELL; IMMUNOREGULATION; INCUBATION TIME; LEUKOCYTOSIS; MOLECULAR RECOGNITION; NEUTROPHIL CHEMOTAXIS; PRIORITY JOURNAL; PROTEIN PROCESSING; SIGNAL PROCESSING;

EID: 0034667542     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.v96.8.2673.h8002673_2673_2681     Document Type: Article

References (67)

1. Purification and identification of 91-kDa neutrophil gelatinase: Release by the activating peptide interleukin-8
2. Gelatinase B: Structure, regulation, and function
3. The molecular basis of leukocytosis
4. Localization of matrix metalloproteinase 9 (92-kilodalton gelatinase/type IV collagenase = gelatinase B) in osteoclasts: Implication for bone resorption
5. MMP-9/gelatinase B is a key regulator of growth plate angiogenesis and apoptosis of hypertrophic chondrocytes
6. Extracellular matrix 6: Role of matrix metalloproteinases in tumor invasion cancer metastasis
7. Inhibition of matrix metalloproteinase 9 expression by a ribozyme blocks metastasis in a rat sarcoma model system
8. Cytokine-regulated proteases in autoimmune diseases
9. Plasminogen activators and matrix metalloproteinases, mediators of extracellular proteolysis in inflammatory demyelination of the central nervous system
10. Substrate specificity and mechanisms of substrate recognition of the matrix metalloproteinases
11. Cytokine-mediated regulation of human leukocyte gelatinases and role in arthritis
12. Chemokines
13. Chemokines - Chemotactic cytokines that mediate inflammation
14. 2-terminal sequence-characterized human monokine possessing neutrophil chemotactic, skin-reactive, and granulocytosispromoting activity
15. The chemotactic activity for granulocytes produced by vitally infected fibroblasts is identical to monocyte-derived interleukin 8
16. Generation of the neutrophil-activating peptide NAP-2 from platelet basic protein or connective tissue-activating peptide III through monocyte proteases
17. Neutrophils can generate their activator neutrophil-activating peptide 2 by proteolytic cleavage of platelet-derived connective tissue-activating peptide III
18. 2-terminal heteregeneity: Functional comparison Of different natural isoforms
19. Amino-terminal processing of chemokine ENA-78 regulates biological activity
20. TNF-α renders human neutrophils responsive to platelet factor 4: Comparison of PF-4 and IL-8 reveals different activity profiles of the two chemokines
21. Inhibition of human umbilical vein endothelial cell proliferation by the CXC chemokine, platelet factor 4 (PF4), is associated with impaired downregulation of p21 (Cip1/WAF1)
22. Posttranslational modifications affect the activity of the human monocyte chemotactic proteins MCP-1 and MCP-2: Identification of MCP-2(6-76) as a natural chemokine inhibitor
23. Aminoterminal truncation of chemokines by CD26/dipeptidyl-peptidase IV: Conversion of RANTES into a potent inhibitor of monocyte chemotaxis and HIV-1-Infection
24. Expression, purification, crystallization and crystallographic characterization of dimeric and monomeric human neutrophil gelatinase associated lipocalin
25. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
26. Purification and identification of natural chemokines
27. Functional comparison of two human monocyte chemotactic protein-2 isoforms, role of amino-terminal pyroglutamic acid and processing by CD26/dipeptidyl peptidase IV
28. IL-8 and NAP-2 differ in their capacities to bind and chemoattract 293 cells transfected with either IL-8 receptor type A or type B
29. A novel coumarin-labelled peptide for sensitive continuous assays of the matrix metalloproteinases
30. Monoclonal antibodies specific for natural human neutrophil gelatinase B used for affinity purification, quantitation by two-site ELISA and inhibition Of enzymatic activity
31. Human hepathoma cells produce an 85 kDa gelatinase regulated by phorbol 12-myristate 13-acetate
32. Isolation and primary structure of NGAL, a novel protein associated with human neutrophil gelatinase
33. Monoclonal antibodies detect different distribution patterns of IL-8 receptor A and IL-8 receptor B on human peripheral blood leukocytes
34. Studies on the ability of 65-kDa and 92-kDa tumor cell gelatinases to degrade type IV collagen
35. Monoclonal antibodies to type IV collagenase recognize a protein with limited sequence homology to interstitial collagenase and stromelysin
36. The interglobular domain of cartilage aggrecan is cleaved by PUMP, gelatinoses, and cathepsin B
37. Matrix metalloproteinases cleave at two distinct sites on human cartilage link protein
38. Human 92- and 72-kilodalton type IV collagenases are elastases
39. Leukocyte gelatinase B cleavage releases encephalitogens from human myelin basic protein
40. Proteolytic inactivation of α1-proteinase inhibitor and α1 -antichymotrypsin by oxidatively activated human neutrophil metalloproteinases
41. Matrilysin is much more efficient than other matrix metalloproteinases in the proteolytic inactivation of α 1-antitrypsin
42. The 84-kDa form of human matrix metalloproteinase-9 degrades substance P and gelatin
43. Structure of baby hamster kidney carbohydrate-binding protein CBP30, an S-type animal lectin
44. Galectin-3 is a novel substrate for human matrix metalloproteinases-2 and -9
45. Generation of biologically active IL-1β by matrix metalloproteinases: A novel caspase-1-independent pathway of IL-1β processing
46. Interleukin-8 in sepsis: Relation to shock and inflammatory mediators
47. Induction of gelatinase B and MCP-2 in baboons during sublethal and lethal bacteraemia
48. Purification of granulocyte chemotactic peptide/interleukin-8 reveals N-terminal sequence heterogeneity similar to that of β-thromboglobulin
49. Three forms of monocyte-derived neutrophil chemotactic factor (MDNCF) distinguished by different lengths of the amino-terminal sequence
50. Endothelial and leukocyte forms of IL-8: Conversion by thrombin and interactions with neutrophils
51. IL-1α or tumor necrosis factor-α stimulate release of three NAP-1/IL-8-related neutrophil chemotactic proteins in human dermal fibroblasts
52. Generation of interleukin-8 by plasmin from AV-LPR-interleukin-8, the human fibroblast-derived neutrophil chemotactic factor
53. Interleukin-8 processing by neutrophil elastase, cathepsin G and proteinase-3
54. 2-terminal residues and evidence for uncoupling of neutrophil chemotaxis, exocytosis, and receptor binding activities
55. A comparative study of the neutrophil stimulatory activity in vitro and pro-inflammatory properties in vivo of 72 amino acid and 77 amino acid IL-8
56. Recombinant tumor necrosis factor-α potentiates neutrophil degranulation in response to host defense cytokines neutrophil-activating peptide 2 and IL-8 by modulating intracellular cyclic AMP levels
57. Mast cell migratory response to interleukin-8 is mediated through interaction with chemokine receptor CXCR2/interleukin-8RB
58. IL-8 induces neutrophil chemotaxis predominantly via type I IL-8 receptors
59. Regulation of the expression of IL-8 receptor A/B by IL-8: Possible functions of each receptor
60. Both interleukin-8 receptors independently mediate chemotaxis: Jurkat cells transfected with IL-8R1 or IL-8R2 migrate in response to IL-8, GRO alpha and NAP-2
61. Different functions for the interleukin 8 receptors (IL-8R) of human neutrophil leukocytes: NADPH oxidase and phospholipase D are activated through IL-8R1 but not IL-8R2
62. A comparison of post-receptor signal transduction events in Jurkat cells transfected with either IL-8R1 or IL-8R2: Chemokine mediated activation of p42/p44 MAP-kinase (ERK-2)
63. Expression and function of the chemokine receptors CXCR1 and CXCR2 in sepsis
64. Metalloproteinases are involved in lipopolysaccharide- and tumor necrosis factor-α-mediated regulation of CXCR1 and CXCR2 chemokine receptor expression
65. Prevention of interleukin-8-induced mobilization of hematopoietic progenitor cells in rhesus monkeys by inhibitory antibodies against gelatinase B (M MP-9)
66. Rapid mobilization of hematopoietic progenitor cells in rhesus monkeys by a single intravenous injection of interleukin-8
67. Endogenous interleukin-8 (IL-8) surges in granulocyte colony-stimulating factor-induced peripheral blood stem cell mobilization