Murine visceral leishmaniasis: IgM and polyclonal B-cell activation lead to disease exacerbation

European Journal of Immunology

Volumn 40, Issue 5, 2010, Pages 1355-1368

  Deak, Eszter ^a   Jayakumar, Asha ^a   Cho, Ka Wing ^a   Goldsmith Pestana, Karen ^a   Dondji, Blaise ^a,c   Lambris, John D ^b   McMahon Pratt, Diane ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c CENTRAL WASHINGTON UNIVERSITY   (United States)

Author keywords

Antibody; C5a; Parasitic protozoan

Indexed keywords

B LYMPHOCYTE ANTIGEN; COMPLEMENT COMPONENT C5A RECEPTOR; GAMMA INTERFERON; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; INTERLEUKIN 10;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY PRODUCTION; ANTIGEN ANTIBODY COMPLEX; ANTIGEN PRESENTATION; ARTICLE; B LYMPHOCYTE ACTIVATION; CELL EXPANSION; COMPLEMENT ACTIVATION; CONTROLLED STUDY; DISEASE EXACERBATION; DISEASE PREDISPOSITION; IMMUNE RESPONSE; INFECTION SENSITIVITY; MOUSE; NONHUMAN; PARASITEMIA; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; VISCERAL LEISHMANIASIS;

ANIMALS; ANTIBODIES, PROTOZOAN; ANTIGEN PRESENTATION; B-LYMPHOCYTES; COMPLEMENT C5A; DISEASE PROGRESSION; FEMALE; HYPERGAMMAGLOBULINEMIA; IMMUNITY, INNATE; IMMUNIZATION, PASSIVE; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; INTERLEUKIN-10; LEISHMANIA INFANTUM; LEISHMANIASIS, VISCERAL; LYMPH NODES; LYMPHOCYTE ACTIVATION; LYMPHOCYTE DEPLETION; MALE; MICE; MICE, INBRED BALB C; MICE, TRANSGENIC; PARASITEMIA;

EID: 77951700217     PISSN: 00142980     EISSN: 15214141     Source Type: Journal    
DOI: 10.1002/eji.200939455     Document Type: Article

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