메뉴 건너뛰기




Volumn 11, Issue , 2011, Pages 1243-1269

Ovarian epithelial cancer stem cells

Author keywords

Cancer stem cell; Chemoresistance; Ovarian epithelial cancer; Pathogenesis; Signaling pathways; Therapy

Indexed keywords

BETA CATENIN; DOXORUBICIN; MESSENGER RNA; METHOTREXATE; NOTCH RECEPTOR; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN KINASE B; SONIC HEDGEHOG PROTEIN; WNT PROTEIN;

EID: 79959664464     PISSN: None     EISSN: 1537744X     Source Type: Journal    
DOI: 10.1100/tsw.2011.112     Document Type: Review
Times cited : (19)

References (257)
  • 6
    • 56749103412 scopus 로고    scopus 로고
    • The cell of origin of ovarian epithelial tumours
    • Dubeau, L. (2008) The cell of origin of ovarian epithelial tumours. Lancet Oncol. 9, 1191-1197.
    • (2008) Lancet Oncol. , vol.9 , pp. 1191-1197
    • Dubeau, L.1
  • 7
    • 77951784627 scopus 로고    scopus 로고
    • Ovarian cancer pathogenesis: A model in evolution
    • Karst A.M. and Drapkin, R. (2010) Ovarian cancer pathogenesis: a model in evolution. J. Oncol. 2010, 932371.
    • (2010) J. Oncol. , vol.2010 , pp. 932371
    • Karst, A.M.1    Drapkin, R.2
  • 8
    • 33750313208 scopus 로고    scopus 로고
    • Cancer stem cells - Perspectives on current status and future directions: AACR workshop on cancer stem cells
    • DOI 10.1158/0008-5472.CAN-06-3126
    • Clarke, M.F., Dick, J.E., Dirks, P., Eaves, C.J., Jamieson, C.H.M., Jones, D.L., Visvader, J., Weissman, I.L., and Wahl, G.M. (2006) Cancer stem cells - perspectives on current status and future directions: AACR Workshop on Cancer Stem Cells. Cancer Res. 66, 9339-9344. (Pubitemid 44623625)
    • (2006) Cancer Research , vol.66 , Issue.19 , pp. 9339-9344
    • Clarke, M.F.1    Dick, J.E.2    Dirks, P.B.3    Eaves, C.J.4    Jamieson, C.H.M.5    Jones, D.L.6    Visvader, J.7    Weissman, I.L.8    Wahl, G.M.9
  • 11
    • 28244472369 scopus 로고    scopus 로고
    • Prospective identification of tumorigenic prostate cancer stem cells
    • DOI 10.1158/0008-5472.CAN-05-2018
    • Collins, A.T., Berry, P.A., Hyde, C., Stower, M.J., and Maitland, N.J. (2005) Prospective identification of tumorigenic prostate cancer stem cells. Cancer Res. 65, 10946-10951. (Pubitemid 41713363)
    • (2005) Cancer Research , vol.65 , Issue.23 , pp. 10946-10951
    • Collins, A.T.1    Berry, P.A.2    Hyde, C.3    Stower, M.J.4    Maitland, N.J.5
  • 13
    • 70449719361 scopus 로고    scopus 로고
    • Identification of human pancreatic cancer stem cells
    • Li, C., Lee, C.J., and Simeone, D.M. (2009) Identification of human pancreatic cancer stem cells. Methods Mol. Biol. 568, 161-173.
    • (2009) Methods Mol. Biol. , vol.568 , pp. 161-173
    • Li, C.1    Lee, C.J.2    Simeone, D.M.3
  • 14
    • 33846100356 scopus 로고    scopus 로고
    • A human colon cancer cell capable of initiating tumour growth in immunodeficient mice
    • DOI 10.1038/nature05372, PII NATURE05372
    • O'Brien, C.A., Pollett, A., Gallinger, S., and Dick, J.E. (2007) A human colon cancer cell capable of initiating tumour growth in immunodeficient mice. Nature 445, 106-110. (Pubitemid 46067310)
    • (2007) Nature , vol.445 , Issue.7123 , pp. 106-110
    • O'Brien, C.A.1    Pollett, A.2    Gallinger, S.3    Dick, J.E.4
  • 15
    • 45549091414 scopus 로고    scopus 로고
    • Prostate cancer stem cells: A new target for therapy
    • Maitland, N.J. and Collins, A.T. (2008) Prostate cancer stem cells: a new target for therapy. J. Clin. Oncol. 26, 2862-2870.
    • (2008) J. Clin. Oncol. , vol.26 , pp. 2862-2870
    • Maitland, N.J.1    Collins, A.T.2
  • 17
    • 1942469352 scopus 로고    scopus 로고
    • Ovarian tumorigenesis: A proposed model based on morphological and molecular genetic analysis
    • Shih, Ie.M. and Kurman, R.J. (2004) Ovarian tumorigenesis: a proposed model based on morphological and molecular genetic analysis. Am. J. Pathol. 164, 1511-1518.
    • (2004) Am. J. Pathol. , vol.164 , pp. 1511-1518
    • Shih, I.M.1    Kurman, R.J.2
  • 18
    • 12844251290 scopus 로고    scopus 로고
    • Patterns of p53 mutations separate ovarian serous borderline tumors and low- and high-grade carcinomas and provide support for a new model of ovarian carcinogenesis: A mutational analysis with immunohistochemical correlation
    • DOI 10.1097/01.pas.0000146025.91953.8d
    • Singer, G., Stöhr, R., Cope, L., Dehari, R., Hartmann, A., Cao, D.F., Wang, T.L., Kurman, R.J., and Shih, I.M. (2005) Patterns of p53 mutations separate ovarian serous borderline tumors and low- and high-grade carcinomas and provide support for a new model of ovarian carcinogenesis: a mutational analysis with immunohistochemical correlation. Am. J. Surg. Pathol. 29, 218-224. (Pubitemid 40170640)
    • (2005) American Journal of Surgical Pathology , vol.29 , Issue.2 , pp. 218-224
    • Singer, G.1    Stohr, R.2    Cope, L.3    Dehari, R.4    Hartmann, A.5    Cao, D.-F.6    Wang, T.-L.7    Kurman, R.J.8    Shih, I.-M.9
  • 19
    • 41349100528 scopus 로고    scopus 로고
    • Pathogenesis of ovarian cancer: Lessons from morphology and molecular biology and their clinical implications
    • DOI 10.1097/PGP.0b013e318161e4f5
    • Kurman, R.J. and Shih, Ie.M. (2008) Pathogenesis of ovarian cancer: lessons from morphology and molecular biology and their clinical implications. Int. J. Gynecol. Pathol. 27, 151-160. (Pubitemid 351450677)
    • (2008) International Journal of Gynecological Pathology , vol.27 , Issue.2 , pp. 151-160
    • Kurman, R.J.1    Shih, I.-M.2
  • 20
    • 77649219639 scopus 로고    scopus 로고
    • The origin and pathogenesis of epithelial ovarian cancer: A proposed unifying theory
    • Kurman, R.J. and Shih, I.M. (2010) The origin and pathogenesis of epithelial ovarian cancer: a proposed unifying theory. Am. J. Surg. Pathol. 34, 433-443.
    • (2010) Am. J. Surg. Pathol. , vol.34 , pp. 433-443
    • Kurman, R.J.1    Shih, I.M.2
  • 22
    • 0028966584 scopus 로고
    • Functional isolation and characterization of human hematopoietic stem cells
    • Berardi, A.C., Wang, A., Levine, J.D., Lopez, P., and Scadden, D.T. (1995) Functional isolation and characterization of human hematopoietic stem cells. Science 267, 104-108.
    • (1995) Science , vol.267 , pp. 104-108
    • Berardi, A.C.1    Wang, A.2    Levine, J.D.3    Lopez, P.4    Scadden, D.T.5
  • 23
    • 0029970965 scopus 로고    scopus 로고
    • Keratin 19 as a biochemical marker of skin stem cells in vivo and in vitro: Keratin 19 expressing cells are differentially localized in function of anatomic sites, and their number varies with donor age and culture stage
    • Michel, M., Török, N., Godbout, M.J., Lussier, M., Gaudreau, P., Royal, A., and Germain, L. (1996) Keratin 19 as a biochemical marker of skin stem cells in vivo and in vitro: keratin 19 expressing cells are differentially localized in function of anatomic sites, and their number varies with donor age and culture stage. J. Cell Sci. 109, 1017-1028.
    • (1996) J. Cell Sci. , vol.109 , pp. 1017-1028
    • Michel, M.1    Török, N.2    Godbout, M.J.3    Lussier, M.4    Gaudreau, P.5    Royal, A.6    Germain, L.7
  • 26
    • 77958485383 scopus 로고    scopus 로고
    • Intestinal stem cell replacement follows a pattern of neutral drift
    • Lopez-Garcia, C., Klein, A.M., Simons, B.D., and Winton, D.J. (2010) Intestinal stem cell replacement follows a pattern of neutral drift. Science 330, 822-825.
    • (2010) Science , vol.330 , pp. 822-825
    • Lopez-Garcia, C.1    Klein, A.M.2    Simons, B.D.3    Winton, D.J.4
  • 27
    • 0037948854 scopus 로고    scopus 로고
    • In vitro propagation and transcriptional profiling of human mammary stem/progenitor cells
    • DOI 10.1101/gad.1061803
    • Dontu, G., Abdallah, W.M., Foley, J.M., Jackson, K.W., Clarke, M.F., Kawamura, M.J., and Wicha, M.S. (2003) In vitro propagation and transcriptional profiling of human mammary stem/progenitor cells. Genes Dev. 17, 1253-1270. (Pubitemid 36583168)
    • (2003) Genes and Development , vol.17 , Issue.10 , pp. 1253-1270
    • Dontu, G.1    Abdallah, W.M.2    Foley, J.M.3    Jackson, K.W.4    Clarke, M.F.5    Kawamura, M.J.6    Wicha, M.S.7
  • 28
    • 0033118412 scopus 로고    scopus 로고
    • Mammalian sex determination: A molecular drama
    • Swain, A. and Lovell-Badge, R. (1999) Mammalian sex determination: a molecular drama. Genes Dev. 13, 755-767. (Pubitemid 29169835)
    • (1999) Genes and Development , vol.13 , Issue.7 , pp. 755-767
    • Swain, A.1    Lovell-Badge, R.2
  • 30
    • 0035008525 scopus 로고    scopus 로고
    • Ovarian surface epithelium: Biology, endocrinology, and pathology
    • DOI 10.1210/er.22.2.255
    • Auersperg, N., Wong, A.S., Choi, K.C., Kang, S.K., and Leung, P.C. (2001) Ovarian surface epithelium: biology, endocrinology, and pathology. Endocr. Rev. 22, 255-288. (Pubitemid 32458162)
    • (2001) Endocrine Reviews , vol.22 , Issue.2 , pp. 255-288
    • Auersperg, N.1    Wong, A.S.T.2    Choi, K.-C.3    Kang, S.K.4    Leung, P.C.K.5
  • 31
    • 42449099540 scopus 로고    scopus 로고
    • The ovary: Anatomy and function throughout human life
    • DOI 10.1196/annals.1434.009, Assessment of Human Reproductive Function
    • Oktem, O. and Oktay, K. (2008) The ovary: anatomy and function throughout human life. Ann. N. Y. Acad. Sci. 1127, 1-9. (Pubitemid 351563102)
    • (2008) Annals of the New York Academy of Sciences , vol.1127 , pp. 1-9
    • Oktem, O.1    Oktay, K.2
  • 32
    • 0034754436 scopus 로고    scopus 로고
    • Ovulation-induced DNA damage in ovarian surface epithelial cells of ewes: Prospective regulatory mechanisms of repair/survival and apoptosis
    • Murdoch, W.J., Townsend, R.S., and McDonnel, A.C. (2001) Ovulation-induced DNA damage in ovarian surface epithelial cells of ewes: prospective regulatory mechanisms of repair/survival and apoptosis. Biol. Reprod. 65, 1417-1424. (Pubitemid 33031499)
    • (2001) Biology of Reproduction , vol.65 , Issue.5 , pp. 1417-1424
    • Murdoch, W.J.1    Townsend, R.S.2    McDonnel, A.C.3
  • 33
    • 0036075402 scopus 로고    scopus 로고
    • Roles of the ovarian surface epithelium in ovulation and carcinogenesis
    • Murdoch, W.J. and McDonnel, A.C. (2002) Roles of the ovarian surface epithelium in ovulation and carcinogenesis. Reproduction 123, 743-750. (Pubitemid 34662050)
    • (2002) Reproduction , vol.123 , Issue.6 , pp. 743-750
    • Murdoch, W.J.1    McDonnel, A.C.2
  • 34
    • 13244262653 scopus 로고    scopus 로고
    • A brief history of the pathology of the gonads
    • Young, R.H. (2005) A brief history of the pathology of the gonads. Mod. Pathol. 18, S3-S17.
    • (2005) Mod. Pathol. , vol.18
    • Young, R.H.1
  • 36
    • 41349101947 scopus 로고    scopus 로고
    • Early detection and treatment of ovarian cancer: Shifting from early stage to minimal volume of disease based on a new model of carcinogenesis
    • DOI 10.1016/j.ajog.2008.01.005, PII S0002937808000203
    • Kurman, R.J., Visvanathan, K., Roden, R., Wu, T.C., and Shih, I.M. (2008) Early detection and treatment of ovarian cancer: shifting from early stage to minimal volume of disease based on a new model of carcinogenesis. Am. J. Obstet. Gynecol. 198, 351-356. (Pubitemid 351451941)
    • (2008) American Journal of Obstetrics and Gynecology , vol.198 , Issue.4 , pp. 351-356
    • Kurman, R.J.1    Visvanathan, K.2    Roden, R.3    Wu, T.C.4    Shih, I.-M.5
  • 37
    • 0036894182 scopus 로고    scopus 로고
    • The stem-cell niche theory: Lessons from flies
    • Lin, H. (2002) The stem-cell niche theory: lessons from flies. Nat. Rev. Genet. 3, 931-940.
    • (2002) Nat. Rev. Genet. , vol.3 , pp. 931-940
    • Lin, H.1
  • 38
    • 33846226547 scopus 로고    scopus 로고
    • The Drosophila ovary: An active stem cell community
    • DOI 10.1038/sj.cr.7310123, PII 7310123
    • Kirilly, D. and Xie, T. (2007) The Drosophila ovary: an active stem cell community. Cell Res. 17, 15-25. (Pubitemid 46096420)
    • (2007) Cell Research , vol.17 , Issue.1 , pp. 15-25
    • Kirilly, D.1    Xie, T.2
  • 39
    • 34247382563 scopus 로고    scopus 로고
    • Notch signaling controls germline stem cell niche formation in the Drosophila ovary
    • DOI 10.1242/dev.003392
    • Song, X., Call, G.B., Kirilly, D., and Xie, T. (2007) Notch signaling controls germline stem cell niche formation in the Drosophila ovary. Development 134, 1071-1080. (Pubitemid 46630075)
    • (2007) Development , vol.134 , Issue.6 , pp. 1071-1080
    • Song, X.1    Call, G.B.2    Kirilly, D.3    Xie, T.4
  • 40
    • 77749327533 scopus 로고    scopus 로고
    • Regulation of epithelial stem cell replacement and follicle formation in the Drosophila ovary
    • Nystul, T. and Spradling, A. (2010) Regulation of epithelial stem cell replacement and follicle formation in the Drosophila ovary. Genetics 184, 503-515.
    • (2010) Genetics , vol.184 , pp. 503-515
    • Nystul, T.1    Spradling, A.2
  • 41
    • 77951833362 scopus 로고    scopus 로고
    • Polycomb group genes Psc and Su(z)2 restrict follicle stem cell self-renewal and extrusion by controlling canonical and noncanonical Wnt signaling
    • Li, X., Han, Y., and Xi, R. (2010) Polycomb group genes Psc and Su(z)2 restrict follicle stem cell self-renewal and extrusion by controlling canonical and noncanonical Wnt signaling. Genes Dev. 24, 933-946.
    • (2010) Genes Dev. , vol.24 , pp. 933-946
    • Li, X.1    Han, Y.2    Xi, R.3
  • 42
    • 67650564912 scopus 로고    scopus 로고
    • Oocyte-specific deletion of Pten in mice reveals a stage-specific function of PTEN/PI3K signaling in oocytes in controlling follicular activation
    • Jagarlamudi, K., Liu, L., Adhikari, D., Reddy, P., Idahl, A., Ottander, U., Lundin, E., and Liu, K. (2009) Oocyte-specific deletion of Pten in mice reveals a stage-specific function of PTEN/PI3K signaling in oocytes in controlling follicular activation. PLoS One 4, e6186.
    • (2009) PLoS One , vol.4
    • Jagarlamudi, K.1    Liu, L.2    Adhikari, D.3    Reddy, P.4    Idahl, A.5    Ottander, U.6    Lundin, E.7    Liu, K.8
  • 43
    • 66649099070 scopus 로고    scopus 로고
    • Dominant activation of the hedgehog signaling pathway in the ovary alters theca development and prevents ovulation
    • Ren, Y., Cowan, R.G., Harman, R.M., and Quirk, S.M. (2009) Dominant activation of the hedgehog signaling pathway in the ovary alters theca development and prevents ovulation. Mol. Endocrinol. 23, 711-723.
    • (2009) Mol. Endocrinol. , vol.23 , pp. 711-723
    • Ren, Y.1    Cowan, R.G.2    Harman, R.M.3    Quirk, S.M.4
  • 45
    • 72149090718 scopus 로고    scopus 로고
    • The primordial pool of follicles and nest breakdown in mammalian ovaries
    • Tingen, C., Kim, A., and Woodruff, T.K. (2009) The primordial pool of follicles and nest breakdown in mammalian ovaries. Mol. Hum. Reprod. 15, 795-803.
    • (2009) Mol. Hum. Reprod. , vol.15 , pp. 795-803
    • Tingen, C.1    Kim, A.2    Woodruff, T.K.3
  • 46
    • 0025313294 scopus 로고
    • Label-retaining cells reside in the bulge area of pilosebaceous unit: Implications for follicular stem cells, hair cycle, and skin carcinogenesis
    • Cotsarelis, G., Sun, T.T., and Lavker, R.M. (1990) Label-retaining cells reside in the bulge area of pilosebaceous unit: implications for follicular stem cells, hair cycle, and skin carcinogenesis. Cell 61, 1329-1337.
    • (1990) Cell , vol.61 , pp. 1329-1337
    • Cotsarelis, G.1    Sun, T.T.2    Lavker, R.M.3
  • 47
    • 0347634454 scopus 로고    scopus 로고
    • Defining the Epithelial Stem Cell Niche in Skin
    • DOI 10.1126/science.1092436
    • Tumbar, T., Guasch, G., Greco, V., Blanpain, C., Lowry, W.E., Rendl, M., and Fuchs, E. (2004) Defining the epithelial stem cell niche in skin. Science 303, 359-363. (Pubitemid 38095773)
    • (2004) Science , vol.303 , Issue.5656 , pp. 359-363
    • Tumbar, T.1    Guasch, G.2    Greco, V.3    Blanpain, C.4    Lowry, W.E.5    Rendl, M.6    Fuchs, R.7
  • 48
    • 0346244093 scopus 로고    scopus 로고
    • Isolation and characterization of functional mammary gland stem cells
    • Welm, B., Behbod, F., Goodell, M.A., and Rosen, J.M. (2003) Isolation and characterization of functional mammary gland stem cells. Cell Prolif. 36, 17-32. (Pubitemid 37521841)
    • (2003) Cell Proliferation, Supplement , vol.36 , Issue.1 , pp. 17-32
    • Welm, B.1    Behbod, F.2    Goodell, M.A.3    Rosen, J.M.4
  • 49
    • 36248949045 scopus 로고    scopus 로고
    • Stem cells and the stem cell niche in the breast: An integrated hormonal and developmental perspective
    • DOI 10.1007/s12015-007-0019-1, PII SCR32147
    • Brisken, C. and Duss, S. (2007) Stem cells and the stem cell niche in the breast: an integrated hormonal and developmental perspective. Stem Cell Rev. 3, 147-156. (Pubitemid 350129717)
    • (2007) Stem Cell Reviews , vol.3 , Issue.2 , pp. 147-156
    • Brisken, C.1    Duss, S.2
  • 50
    • 60149083378 scopus 로고    scopus 로고
    • Parthenogenetic embryo-like structures in the human ovarian surface epithelium cell culture in postmenopausal women with no naturally present follicles and oocytes
    • Virant-Klun, I., Rozman, P., Cvjeticanin, B., Vrtacnik-Bokal, E., Novakovic, S., Rülicke, T., Dovc, P., and Meden-Vrtovec, H. (2009) Parthenogenetic embryo-like structures in the human ovarian surface epithelium cell culture in postmenopausal women with no naturally present follicles and oocytes. Stem Cells Dev. 18, 137-149.
    • (2009) Stem Cells Dev. , vol.18 , pp. 137-149
    • Virant-Klun, I.1    Rozman, P.2    Cvjeticanin, B.3    Vrtacnik-Bokal, E.4    Novakovic, S.5    Rülicke, T.6    Dovc, P.7    Meden-Vrtovec, H.8
  • 55
    • 25444485195 scopus 로고    scopus 로고
    • Contribution of the ABC transporters Bcrp1 and Mdr1a/1b to the side population phenotype in mammary gland and bone marrow of mice
    • Jonker, J.W., Freeman, J., Bolscher, E., Musters, S., Alvi, A.J., Titley, I., Schinkel, A.H., and Dale, T.C. (2005) Contribution of the ABC transporters Bcrp1 and Mdr1a/1b to the side population phenotype in mammary gland and bone marrow of mice. Stem Cells 23, 1059-1065.
    • (2005) Stem Cells , vol.23 , pp. 1059-1065
    • Jonker, J.W.1    Freeman, J.2    Bolscher, E.3    Musters, S.4    Alvi, A.J.5    Titley, I.6    Schinkel, A.H.7    Dale, T.C.8
  • 58
    • 0026446445 scopus 로고
    • Human ovarian surface epithelial cells are capable of physically restructuring extracellular matrix
    • Kruk, P.A. and Auersperg, N. (1992) Human ovarian surface epithelial cells are capable of physically restructuring extracellular matrix. Am. J. Obstet. Gynecol. 167, 1437-1443.
    • (1992) Am. J. Obstet. Gynecol. , vol.167 , pp. 1437-1443
    • Kruk, P.A.1    Auersperg, N.2
  • 59
    • 0027946429 scopus 로고
    • Characterization of cultured human ovarian surface epithelial cells: Phenotypic plasticity and premalignant changes
    • Auersperg, N., Maines-Bandiera, S.L., Dyck, H.G., and Kruk, P.A. (1994) Characterization of cultured human ovarian surface epithelial cells: phenotypic plasticity and premalignant changes. Lab. Invest. 71, 510-518. (Pubitemid 24338158)
    • (1994) Laboratory Investigation , vol.71 , Issue.4 , pp. 510-518
    • Auersperg, N.1    Maines-Bandiera, S.L.2    Dyck, H.G.3    Kruk, P.A.4
  • 60
    • 0028116746 scopus 로고
    • Reciprocal interactions between human ovarian surface epithelial cells and adjacent extracellular matrix
    • DOI 10.1006/excr.1994.1320
    • Kruk, P.A., Uitto, V.J., Firth, J.D., Dedhar, S., and Auersperg, N. (1994) Reciprocal interactions between human ovarian surface epithelial cells and adjacent extracellular matrix. Exp. Cell Res. 215, 97-108. (Pubitemid 24339179)
    • (1994) Experimental Cell Research , vol.215 , Issue.1 , pp. 97-108
    • Kruk, P.A.1    Uitto, V.-J.2    Firth, J.D.3    Dedhar, S.4    Auersperg, N.5
  • 63
    • 0027463615 scopus 로고
    • The biology of ovarian cancer development
    • Godwin, A.K., Testa, J.R., and Hamilton, T.C. (1993) The biology of ovarian cancer development. Cancer 71, 530-536. (Pubitemid 23021247)
    • (1993) Cancer , vol.71 , Issue.2 SUPPL. , pp. 530-536
    • Godwin, A.K.1    Testa, J.R.2    Hamilton, T.C.3
  • 64
    • 0033199807 scopus 로고    scopus 로고
    • Possible role of ovarian epithelial inflammation in ovarian cancer
    • Ness, R.B. and Cottreau, C. (1999) Possible role of ovarian epithelial inflammation in ovarian cancer. Natl. Cancer Inst. 91, 1459-1467. (Pubitemid 29424550)
    • (1999) Journal of the National Cancer Institute , vol.91 , Issue.17 , pp. 1459-1467
    • Ness, R.B.1    Cottreau, C.2
  • 65
    • 67349190538 scopus 로고    scopus 로고
    • Precursors to pelvic serous carcinoma and their clinical implications
    • Folkins, A.K., Jarboe, E.A., Roh, M.H., and Crum, C.P. (2009) Precursors to pelvic serous carcinoma and their clinical implications. Gynecol. Oncol. 113, 391-396.
    • (2009) Gynecol. Oncol. , vol.113 , pp. 391-396
    • Folkins, A.K.1    Jarboe, E.A.2    Roh, M.H.3    Crum, C.P.4
  • 66
    • 2942594342 scopus 로고    scopus 로고
    • Oxidative damage to DNA of ovarian surface epithelial cells affected by ovulation: Carcinogenic implication and chemoprevention
    • Murdoch, W.J. and Martinchick, J.F. (2004) Oxidative damage to DNA of ovarian surface epithelial cells affected by ovulation: carcinogenic implication and chemoprevention. Exp. Biol. Med. 229, 546-552. (Pubitemid 38736324)
    • (2004) Experimental Biology and Medicine , vol.229 , Issue.6 , pp. 546-552
    • Murdoch, W.J.1    Martinchick, J.F.2
  • 67
    • 0026587992 scopus 로고
    • Spontaneous transformation of rat ovarian surface epithelial cells: Association with cytogenetic changes and implications of repeated ovulation in the etiology of ovarian cancer
    • Godwin, A.K., Testa, J.R., Handel, L.M., Liu, Z., Vanderveer, L.A., Tracey, P.A., and Hamilton, T.C. (1992) Spontaneous transformation of rat ovarian surface epithelial cells: association with cytogenetic changes and implications of repeated ovulation in the etiology of ovarian cancer. J. Natl. Cancer Inst. 84, 592-601.
    • (1992) J. Natl. Cancer Inst. , vol.84 , pp. 592-601
    • Godwin, A.K.1    Testa, J.R.2    Handel, L.M.3    Liu, Z.4    Vanderveer, L.A.5    Tracey, P.A.6    Hamilton, T.C.7
  • 68
    • 0028261059 scopus 로고
    • Spontaneous transformation of rat ovarian surface epithelial cells results in well to poorly differentiated tumors with a parallel range of cytogenetic complexity
    • Testa, J.R., Getts, L.A., Salazar, H., Liu, Z., Handel, L.M., Godwin, A.K., and Hamilton, T.C. (1994) Spontaneous transformation of rat ovarian surface epithelial cells results in well to poorly differentiated tumors with a parallel range of cytogenetic complexity. Cancer Res. 54, 2778-2784. (Pubitemid 24173774)
    • (1994) Cancer Research , vol.54 , Issue.10 , pp. 2778-2784
    • Testa, J.R.1    Getts, L.A.2    Salazar, H.3    Liu, Z.4    Handel, L.M.5    Godwin, A.K.6    Hamilton, T.C.7
  • 69
    • 39749171410 scopus 로고    scopus 로고
    • Early events in the pathogenesis of epithelial ovarian cancer
    • DOI 10.1200/JCO.2006.07.9970
    • Landen, C.N., Jr., Birrer, M.J., and Sood, A.K. (2008) Early events in the pathogenesis of epithelial ovarian cancer. J. Clin. Oncol. 26, 995-1005. (Pubitemid 351398093)
    • (2008) Journal of Clinical Oncology , vol.26 , Issue.6 , pp. 995-1005
    • Landen Jr., C.N.1    Birrer, M.J.2    Sood, A.K.3
  • 70
    • 0036928961 scopus 로고    scopus 로고
    • Pathologic findings in prophylactic oophorectomy specimens in high-risk women
    • DOI 10.1006/gyno.2002.6779
    • Leeper, K., Garcia, R., Swisher, E., Goff, B., Greer, B., and Paley, P. (2002) Pathologic findings in prophylactic oophorectomy specimens in high-risk women. Gynecol. Oncol. 87, 52-56. (Pubitemid 36027101)
    • (2002) Gynecologic Oncology , vol.87 , Issue.1 , pp. 52-56
    • Leeper, K.1    Garcia, R.2    Swisher, E.3    Goff, B.4    Greer, B.5    Paley, P.6
  • 71
    • 0346251021 scopus 로고    scopus 로고
    • Atypical Epithelial Proliferation in Fallopian Tubes in Prophylactic Salpingo-oophorectomy Specimens from BRCA1 and BRCA2 Germline Mutation Carriers
    • DOI 10.1097/01.pgp.0000101082.35393.84
    • Carcangiu, M.L., Radice, P., Manoukian, S., Spatti, G., Gobbo, M., Pensotti, V., Crucianelli, R., and Pasini, B. (2004) Atypical epithelial proliferation in fallopian tubes in prophylactic salpingo-oophorectomy specimens from BRCA1 and BRCA2 germline mutation carriers. Int. J. Gynecol. Pathol. 23, 35-40. (Pubitemid 38018235)
    • (2004) International Journal of Gynecological Pathology , vol.23 , Issue.1 , pp. 35-40
    • Carcangiu, M.L.1    Radice, P.2    Manoukian, S.3    Spatti, G.4    Gobbo, M.5    Pensotti, V.6    Crucianelli, R.7    Pasini, B.8
  • 74
    • 4944250783 scopus 로고    scopus 로고
    • Mutations of BRAF and KRAS precede the development of ovarian serous borderline tumors
    • DOI 10.1158/0008-5472.CAN-04-2067
    • Ho, C.L., Kurman, R.J., Dehari, R., Wang, T.L., and Shih, I.M. (2004) Mutations of BRAF and KRAS precede the development of ovarian serous borderline tumors. Cancer Res. 64, 6915-6918. (Pubitemid 39330999)
    • (2004) Cancer Research , vol.64 , Issue.19 , pp. 6915-6918
    • Ho, C.-L.1    Kurman, R.J.2    Dehari, R.3    Wang, T.-L.4    Shih, I.-M.5
  • 75
    • 0037148532 scopus 로고    scopus 로고
    • Ras and TGFbeta cooperatively regulate epithelial cell plasticity and metastasis: Dissection of Ras signaling pathways
    • DOI 10.1083/jcb.200109037
    • Janda, E., Lehmann, K., Killisch, I., Jechlinger, M., Herzig, M., Downward, J., Beug, H, and Grünert, S. (2002) Ras and TGF[beta] cooperatively regulate epithelial cell plasticity and metastasis: dissection of Ras signaling pathways. J. Cell Biol. 156, 299-313. (Pubitemid 34839911)
    • (2002) Journal of Cell Biology , vol.156 , Issue.2 , pp. 299-313
    • Janda, E.1    Lehmann, K.2    Killisch, I.3    Jechlinger, M.4    Herzig, M.5    Downward, J.6    Beug, H.7    Grunert, S.8
  • 76
    • 27144519156 scopus 로고    scopus 로고
    • Molecular pathogenesis of ovarian borderline tumors: New insights and old challenges
    • Shih, Ie.M. and Kurman, R.J. (2005) Molecular pathogenesis of ovarian borderline tumors: new insights and old challenges. Clin. Cancer Res. 11, 7273-7279.
    • (2005) Clin. Cancer Res. , vol.11 , pp. 7273-7279
    • Shih, I.M.1    Kurman, R.J.2
  • 78
    • 0036595629 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transitions in tumour progression
    • Thiery, J.P. (2002) Epithelial-mesenchymal transitions in tumour progression. Nat. Rev. Cancer 2, 442-454.
    • (2002) Nat. Rev. Cancer , vol.2 , pp. 442-454
    • Thiery, J.P.1
  • 79
    • 44449144396 scopus 로고    scopus 로고
    • Epithelial-Mesenchymal Transition: At the Crossroads of Development and Tumor Metastasis
    • DOI 10.1016/j.devcel.2008.05.009, PII S1534580708002098
    • Yang, J. and Weinberg, R.A. (2008) Epithelial-mesenchymal transition: at the crossroads of development and tumor metastasis. Dev. Cell 14, 818-829. (Pubitemid 351757205)
    • (2008) Developmental Cell , vol.14 , Issue.6 , pp. 818-829
    • Yang, J.1    Weinberg, R.A.2
  • 83
    • 0034707053 scopus 로고    scopus 로고
    • In search of the tumour-suppressor functions of BRCA1 and BRCA2
    • Scully, R. and Livingston, D.M. (2000) In search of the tumour-suppressor functions of BRCA1 and BRCA2. Nature 408, 429-432.
    • (2000) Nature , vol.408 , pp. 429-432
    • Scully, R.1    Livingston, D.M.2
  • 84
    • 0034088090 scopus 로고    scopus 로고
    • Analysis of MLH1 and MSH2 expression in ovarian cancer before and after platinum drug-based chemotherapy
    • Samimi, G., Fink, D., Varki, N.M., Husain, A., Hoskins, W.J., Alberts, D.S., and Howell, S.B. (2000) Analysis of MLH1 and MSH2 expression in ovarian cancer before and after platinum drug-based chemotherapy. Clin. Cancer Res. 6, 1415-1421. (Pubitemid 30226229)
    • (2000) Clinical Cancer Research , vol.6 , Issue.4 , pp. 1415-1421
    • Samimi, G.1    Fink, D.2    Varki, N.M.3    Husain, A.4    Hoskins, W.J.5    Alberts, D.S.6    Howell, S.B.7
  • 86
    • 59449096085 scopus 로고    scopus 로고
    • Consideration of hereditary nonpolyposis colorectal cancer in BRCA mutation-negative familial ovarian cancers
    • South, S.A., Vance, H., Farrell, C., DiCioccio, RA, Fahey, C., Piver, M.S., and Rodabaugh, K.J. (2009) Consideration of hereditary nonpolyposis colorectal cancer in BRCA mutation-negative familial ovarian cancers. Cancer 115, 324-333.
    • (2009) Cancer , vol.115 , pp. 324-333
    • South, S.A.1    Vance, H.2    Farrell, C.3    DiCioccio, R.A.4    Fahey, C.5    Piver, M.S.6    Rodabaugh, K.J.7
  • 87
    • 33244483383 scopus 로고    scopus 로고
    • Incessant ovulation, inflammation and epithelial ovarian carcinogenesis: Revisiting old hypotheses
    • DOI 10.1016/j.mce.2005.09.014, PII S0303720705003400
    • Fleming, J.S., Beaugié, C.R., Haviv, I., Chenevix-Trench, G., and Tan, O.L. (2006) Incessant ovulation, inflammation and epithelial ovarian carcinogenesis: revisiting old hypotheses. Mol. Cell. Endocrinol. 247, 4-21. (Pubitemid 43277703)
    • (2006) Molecular and Cellular Endocrinology , vol.247 , Issue.1-2 , pp. 4-21
    • Fleming, J.S.1    Beaugie, C.R.2    Haviv, I.3    Chenevix-Trench, G.4    Tan, O.L.5
  • 92
    • 67549148930 scopus 로고    scopus 로고
    • Cystic and adenofibromatous clear cell carcinomas of the ovary: Distinctive tumors that differ in their pathogenesis and behavior: A clinicopathologic analysis of 122 cases
    • Veras, E., Mao, T.L., Ayhan, A., Ueda, S., Lai, H., Hayran, M., Shih, I.M., and Kurman, R.J. (2009) Cystic and adenofibromatous clear cell carcinomas of the ovary: distinctive tumors that differ in their pathogenesis and behavior: a clinicopathologic analysis of 122 cases. Am. J. Surg. Pathol. 33, 844-853.
    • (2009) Am. J. Surg. Pathol. , vol.33 , pp. 844-853
    • Veras, E.1    Mao, T.L.2    Ayhan, A.3    Ueda, S.4    Lai, H.5    Hayran, M.6    Shih, I.M.7    Kurman, R.J.8
  • 94
    • 43049099384 scopus 로고    scopus 로고
    • Genomic analysis of epithelial ovarian cancer
    • DOI 10.1038/cr.2008.52, PII CR200852
    • Farley, J., Ozbun, L.L., and Birrer, M.J. (2008) Genomic analysis of epithelial ovarian cancer. Cell Res. 18, 538-548. (Pubitemid 351630950)
    • (2008) Cell Research , vol.18 , Issue.5 , pp. 538-548
    • Farley, J.1    Ozbun, L.L.2    Birrer, M.J.3
  • 95
    • 85047690508 scopus 로고    scopus 로고
    • The origin of the cancer stem cell: Current controversies and new insights
    • DOI 101038/nrc1740
    • Bjerkvig, R., Tysnes, B.B., Aboody, K.S., Najbauer, J., and Terzis, A.J. (2005) Opinion: the origin of the cancer stem cell: current controversies and new insights. Nat. Rev. Cancer 5, 899-904. (Pubitemid 41746034)
    • (2005) Nature Reviews Cancer , vol.5 , Issue.11 , pp. 899-904
    • Bjerkvig, R.1    Tysnes, B.B.2    Aboody, K.S.3    Najbauer, J.4    Terzis, A.J.A.5
  • 97
    • 79951673159 scopus 로고    scopus 로고
    • Characterization of hybrid cells derived from spontaneous fusion events between breast epithelial cells exhibiting stem-like characteristics and breast cancer cells
    • Dittmar, T., Schwitalla, S., Seidel, J., Haverkampf, S., Reith, G., Meyer-Staeckling, S., Brandt, B.H., Niggemann, B., and Zänker, K.S. (2011) Characterization of hybrid cells derived from spontaneous fusion events between breast epithelial cells exhibiting stem-like characteristics and breast cancer cells. Clin. Exp. Metastasis 28, 75-90.
    • (2011) Clin. Exp. Metastasis , vol.28 , pp. 75-90
    • Dittmar, T.1    Schwitalla, S.2    Seidel, J.3    Haverkampf, S.4    Reith, G.5    Meyer-Staeckling, S.6    Brandt, B.H.7    Niggemann, B.8    Zänker, K.S.9
  • 98
    • 77954186242 scopus 로고    scopus 로고
    • A cancer stem cell origin for human endometrial carcinoma?
    • Hubbard, S.A. and Gargett, C.E. (2010) A cancer stem cell origin for human endometrial carcinoma? Reproduction 140, 23-32.
    • (2010) Reproduction , vol.140 , pp. 23-32
    • Hubbard, S.A.1    Gargett, C.E.2
  • 99
    • 40649108109 scopus 로고    scopus 로고
    • Origin of cancer stem cells: The role of self-renewal and differentiation
    • Wu, X.Z. (2008) Origin of cancer stem cells: the role of self-renewal and differentiation. Ann. Surg. Oncol. 15, 407-414.
    • (2008) Ann. Surg. Oncol. , vol.15 , pp. 407-414
    • Wu, X.Z.1
  • 101
    • 33645214627 scopus 로고    scopus 로고
    • Extracellular matrix remodeling in hepatocellular carcinoma: Effects of soil on seed?
    • Wu, X.Z., Chen, D., and Xie, G.R. (2006) Extracellular matrix remodeling in hepatocellular carcinoma: effects of soil on seed? Med. Hypotheses 66, 1115-1120.
    • (2006) Med. Hypotheses , vol.66 , pp. 1115-1120
    • Wu, X.Z.1    Chen, D.2    Xie, G.R.3
  • 103
    • 29144527583 scopus 로고    scopus 로고
    • Clinical and pathologic findings of prophylactic salpingo-oophorectomies in 159 BRCA1 and BRCA2 carriers
    • DOI 10.1016/j.ygyno.2005.06.065, PII S0090825805004968
    • Finch, A., Shaw, P., Rosen, B., Murphy, J., Narod, S.A., and Colgan, T.J. (2006) Clinical and pathologic findings of prophylactic salpingo-oophorectomies in 159 BRCA1 and BRCA2 carriers. Gynecol. Oncol. 100, 58-64. (Pubitemid 41815050)
    • (2006) Gynecologic Oncology , vol.100 , Issue.1 , pp. 58-64
    • Finch, A.1    Shaw, P.2    Rosen, B.3    Murphy, J.4    Narod, S.A.5    Colgan, T.J.6
  • 107
    • 55949089955 scopus 로고    scopus 로고
    • New insights into the pathogenesis of serous ovarian cancer and its clinical impact
    • Levanon, K., Crum, C., and Drapkin, R. (2008) New insights into the pathogenesis of serous ovarian cancer and its clinical impact. J. Clin. Oncol. 26, 5284-5293.
    • (2008) J. Clin. Oncol. , vol.26 , pp. 5284-5293
    • Levanon, K.1    Crum, C.2    Drapkin, R.3
  • 108
    • 55649115101 scopus 로고    scopus 로고
    • Risk factors for a serous cancer precursor ("p53 signature") in women with inherited BRCA mutations
    • Saleemuddin, A., Folkins, A.K., Garrett, L., Garber, J., Muto, M.G., Crum, C.P., and Tworoger, S. (2008) Risk factors for a serous cancer precursor ("p53 signature") in women with inherited BRCA mutations. Gynecol. Oncol. 111, 226-232.
    • (2008) Gynecol. Oncol. , vol.111 , pp. 226-232
    • Saleemuddin, A.1    Folkins, A.K.2    Garrett, L.3    Garber, J.4    Muto, M.G.5    Crum, C.P.6    Tworoger, S.7
  • 110
    • 36248974666 scopus 로고    scopus 로고
    • The Müllerian duct: Recent insights into its development and regression
    • DOI 10.1159/000108929
    • Klattig, J. and Englert, C. (2007) The Müllerian duct: recent insights into its development and regression. Sex. Dev. 1, 271-278. (Pubitemid 350136531)
    • (2007) Sexual Development , vol.1 , Issue.5 , pp. 271-278
    • Klattig, J.1    Englert, C.2
  • 111
    • 0025911185 scopus 로고
    • Primary peritoneal papillary serous adenocarcinoma: Clinical and management aspects
    • Altaras, M.M., Aviram, R., Cohen, I., Cordoba, M., Weiss, E., and Beyth, Y. (1991) Primary peritoneal papillary serous adenocarcinoma: clinical and management aspects. Gynecol. Oncol. 40, 230-236.
    • (1991) Gynecol. Oncol. , vol.40 , pp. 230-236
    • Altaras, M.M.1    Aviram, R.2    Cohen, I.3    Cordoba, M.4    Weiss, E.5    Beyth, Y.6
  • 113
    • 0036172957 scopus 로고    scopus 로고
    • Papillary serous carcinoma of the peritoneum coexisting with or after endometrial carcinoma
    • DOI 10.1006/gyno.2001.6492
    • Altaras, M.M., Bernheim, J., Zehavi, T., Drucker, L., Uziel, O., and Fishman, A. (2002) Papillary serous carcinoma of the peritoneum coexisting with or after endometrial carcinoma. Gynecol. Oncol. 84, 245-251. (Pubitemid 34136775)
    • (2002) Gynecologic Oncology , vol.84 , Issue.2 , pp. 245-251
    • Altaras, M.M.1    Bernheim, J.2    Zehavi, T.3    Fishman, A.4
  • 114
    • 8544264615 scopus 로고    scopus 로고
    • Peritoneal carcinoma in women with genetic susceptibility: Implications for Jewish populations
    • Casey, M.J. and Bewtra, C. (2004) Peritoneal carcinoma in women with genetic susceptibility: implications for Jewish populations. Fam. Cancer 3, 265-281.
    • (2004) Fam. Cancer , vol.3 , pp. 265-281
    • Casey, M.J.1    Bewtra, C.2
  • 117
    • 18344373769 scopus 로고    scopus 로고
    • Lineage infidelity of epithelial ovarian cancers is controlled by HOX genes that specify regional identity in the reproductive tract
    • DOI 10.1038/nm1230
    • Cheng, W., Liu, J., Yoshida, H., Rosen, D., and Naora, H. (2005) Lineage infidelity of epithelial ovarian cancers is controlled by HOX genes that specify regional identity in the reproductive tract. Nat. Med. 11, 531-537. (Pubitemid 40685976)
    • (2005) Nature Medicine , vol.11 , Issue.5 , pp. 531-537
    • Cheng, W.1    Liu, J.2    Yoshida, H.3    Rosen, D.4    Naora, H.5
  • 118
    • 0028167466 scopus 로고
    • The secondary müllerian system revisited
    • Lauchlan, S.C. (1994) The secondary müllerian system revisited. Int. J. Gynecol. Pathol. 13, 73-79.
    • (1994) Int. J. Gynecol. Pathol. , vol.13 , pp. 73-79
    • Lauchlan, S.C.1
  • 119
    • 2642585666 scopus 로고    scopus 로고
    • Clonogenicity of human endometrial epithelial and stromal cells
    • DOI 10.1095/biolreprod.103.024109
    • Chan, R.W., Schwab, K.E., and Gargett, C.E. (2004) Clonogenicity of human endometrial epithelial and stromal cells. Biol. Reprod. 70, 1738-1750. (Pubitemid 38715630)
    • (2004) Biology of Reproduction , vol.70 , Issue.6 , pp. 1738-1750
    • Chan, R.W.S.1    Schwab, K.E.2    Gargett, C.E.3
  • 120
    • 33845601343 scopus 로고    scopus 로고
    • Identification, characterization and co-localization of label-retaining cell population in mouse endometrium with typical undifferentiated markers
    • Cervelló, I., Martínez-Conejero, J.A., Horcajadas, J.A., Pellicer,A., and Simón, C. (2007) Identification, characterization and co-localization of label-retaining cell population in mouse endometrium with typical undifferentiated markers. Hum. Reprod. 22, 45-51.
    • (2007) Hum. Reprod. , vol.22 , pp. 45-51
    • Cervelló, I.1    Martínez-Conejero, J.A.2    Horcajadas, J.A.3    Pellicer, A.4    Simón, C.5
  • 123
    • 38449083340 scopus 로고    scopus 로고
    • Demonstration of multipotent stem cells in the adult human endometrium by in vitro chondrogenesis
    • DOI 10.1177/1933719107306896
    • Wolff, E.F., Wolff, A.B., Hongling Du., and Taylor, H.S. (2007) Demonstration of multipotent stem cells in the adult human endometrium by in vitro chondrogenesis. Reprod. Sci. 14, 524-533. (Pubitemid 351168784)
    • (2007) Reproductive Sciences , vol.14 , Issue.6 , pp. 524-533
    • Wolff, E.F.1    Wolff, A.B.2    Du, H.3    Taylor, H.S.4
  • 124
    • 44249088606 scopus 로고    scopus 로고
    • Identification of surface markers for prospective isolation of human endometrial stromal colony-forming cells
    • Schwab, K.E., Hutchinson, P., and Gargett, C.E. (2008) Identification of surface markers for prospective isolation of human endometrial stromal colony-forming cells. Hum. Reprod. 23, 934-943.
    • (2008) Hum. Reprod. , vol.23 , pp. 934-943
    • Schwab, K.E.1    Hutchinson, P.2    Gargett, C.E.3
  • 126
    • 74849123453 scopus 로고    scopus 로고
    • Gene expression profiling supports the hypothesis that human ovarian surface epithelia are multipotent and capable of serving as ovarian cancer initiating cells
    • Bowen, N.J., Walker, L.D., Matyunina, L.V., Logani, S., Totten, K.A., Benigno, B.B., and McDonald, J.F. (2009) Gene expression profiling supports the hypothesis that human ovarian surface epithelia are multipotent and capable of serving as ovarian cancer initiating cells. BMC Med. Genomics 29, 71.
    • (2009) BMC Med. Genomics , vol.29 , pp. 71
    • Bowen, N.J.1    Walker, L.D.2    Matyunina, L.V.3    Logani, S.4    Totten, K.A.5    Benigno, B.B.6    McDonald, J.F.7
  • 127
    • 77954196772 scopus 로고    scopus 로고
    • Human ovarian cancer stem cells
    • Bapat, S.A. (2010) Human ovarian cancer stem cells. Reproduction 140, 33-41.
    • (2010) Reproduction , vol.140 , pp. 33-41
    • Bapat, S.A.1
  • 128
    • 17144403478 scopus 로고    scopus 로고
    • Stem and progenitor-like cells contribute to the aggressive behavior of human epithelial ovarian cancer
    • Bapat, S.A., Mali, A.M., Koppikar, C.B., and Kurrey, N.K. (2005) Stem and progenitor-like cells contribute to the aggressive behavior of human epithelial ovarian cancer. Cancer Res. 65, 3025-3029. (Pubitemid 40524578)
    • (2005) Cancer Research , vol.65 , Issue.8 , pp. 3025-3029
    • Bapat, S.A.1    Mali, A.M.2    Koppikar, C.B.3    Kurrey, N.K.4
  • 130
    • 78650756162 scopus 로고    scopus 로고
    • Description of the CD133+ subpopulation of the human ovarian cancer cell line OVCAR3
    • Guo, R., Wu, Q., Liu, F., and Wang, Y. (2011) Description of the CD133+ subpopulation of the human ovarian cancer cell line OVCAR3. Oncol. Rep. 25, 141-146.
    • (2011) Oncol. Rep. , vol.25 , pp. 141-146
    • Guo, R.1    Wu, Q.2    Liu, F.3    Wang, Y.4
  • 132
    • 77950794030 scopus 로고    scopus 로고
    • Pluripotency factors Lin28 and Oct4 identify a sub-population of stem celllike cells in ovarian cancer
    • Peng, S., Maihle, N.J., and Huang, Y. (2010) Pluripotency factors Lin28 and Oct4 identify a sub-population of stem celllike cells in ovarian cancer. Oncogene 29, 2153-2159.
    • (2010) Oncogene , vol.29 , pp. 2153-2159
    • Peng, S.1    Maihle, N.J.2    Huang, Y.3
  • 133
    • 0029958876 scopus 로고    scopus 로고
    • Isolation and functional properties of murine hematopoietic stem cells that are replicating in vivo
    • DOI 10.1084/jem.183.4.1797
    • Goodell, M.A., Brose, K., Paradis, G., Conner, A.S., and Mulligan, R.C. (1996) Isolation and functional properties of murine hematopoietic stem cells that are replicating in vivo. J. Exp. Med. 183, 1797-1806. (Pubitemid 26134320)
    • (1996) Journal of Experimental Medicine , vol.183 , Issue.4 , pp. 1797-1806
    • Goodell, M.A.1    Brose, K.2    Paradis, G.3    Conner, A.S.4    Mulligan, R.C.5
  • 134
    • 33845222483 scopus 로고    scopus 로고
    • Purification of Hematopoietic Stem Cells Using the Side Population
    • DOI 10.1016/S0076-6879(06)20011-9, PII S0076687906200119, Stem Cell Tools and Other Experimental Protocols
    • Lin, K.K. and Goodell, M.A. (2006) Purification of hematopoietic stem cells using the side population. Methods Enzymol. 420, 255-264. (Pubitemid 44855867)
    • (2006) Methods in Enzymology , vol.420 , pp. 255-264
    • Lin, K.K.1    Goodell, M.A.2
  • 136
    • 58449125163 scopus 로고    scopus 로고
    • Epidermal stem cells: Location, potential and contribution to cancer
    • Ambler, C.A. and Maatta, A. (2009) Epidermal stem cells: location, potential and contribution to cancer. J. Pathol. 217, 206-216.
    • (2009) J. Pathol. , vol.217 , pp. 206-216
    • Ambler, C.A.1    Maatta, A.2
  • 137
    • 70149124370 scopus 로고    scopus 로고
    • Identification of cancer stem-like side population cells in ovarian cancer cell line OVCAR-3
    • Gao, Q., Geng, L., Kvalheim, G., Gaudernack, G., and Suo, Z. (2009) Identification of cancer stem-like side population cells in ovarian cancer cell line OVCAR-3. Ultrastruct. Pathol. 33, 175-181.
    • (2009) Ultrastruct. Pathol. , vol.33 , pp. 175-181
    • Gao, Q.1    Geng, L.2    Kvalheim, G.3    Gaudernack, G.4    Suo, Z.5
  • 139
    • 42049109699 scopus 로고    scopus 로고
    • MCF7 side population cells with characteristics of cancer stem/progenitor cells express the tumor antigen MUC1
    • DOI 10.1158/0008-5472.CAN-07-2249
    • Engelmann, K., Shen, H., and Finn, O.J. (2008) MCF7 side population cells with characteristics of cancer stem/progenitor cells express the tumor antigen MUC1. Cancer Res. 68, 2419-2426. (Pubitemid 351521817)
    • (2008) Cancer Research , vol.68 , Issue.7 , pp. 2419-2426
    • Engelmann, K.1    Shen, H.2    Finn, O.J.3
  • 140
    • 77950862035 scopus 로고    scopus 로고
    • Ovarian cancer stem-like side-population cells are tumourigenic and chemoresistant
    • Hu, L., McArthur, C., and Jaffe, R.B. (2010) Ovarian cancer stem-like side-population cells are tumourigenic and chemoresistant. Br. J. Cancer 102, 1276-1283.
    • (2010) Br. J. Cancer , vol.102 , pp. 1276-1283
    • Hu, L.1    McArthur, C.2    Jaffe, R.B.3
  • 142
    • 33846959831 scopus 로고    scopus 로고
    • Identification of label-retaining cells in nasopharyngeal epithelia and nasopharyngeal carcinoma tissues
    • Zhang, H.B., Ren, C.P., Yang, X.Y., Wang, L., Li, H., Zhao, M., Yang, H., and Yao, K.T. (2007) Identification of label-retaining cells in nasopharyngeal epithelia and nasopharyngeal carcinoma tissues. Histochem. Cell Biol. 127, 347-354.
    • (2007) Histochem. Cell Biol. , vol.127 , pp. 347-354
    • Zhang, H.B.1    Ren, C.P.2    Yang, X.Y.3    Wang, L.4    Li, H.5    Zhao, M.6    Yang, H.7    Yao, K.T.8
  • 144
    • 45549100605 scopus 로고    scopus 로고
    • Melanoma stem cells: The dark seed of melanoma
    • Zabierowski, S.E. and Herlyn, M. (2008) Melanoma stem cells: the dark seed of melanoma. J. Clin. Oncol. 26, 2890-2894.
    • (2008) J. Clin. Oncol. , vol.26 , pp. 2890-2894
    • Zabierowski, S.E.1    Herlyn, M.2
  • 145
    • 48949119473 scopus 로고    scopus 로고
    • Human breast cancer cell lines contain stem-like cells that self-renew, give rise to phenotypically diverse progeny and survive chemotherapy
    • Fillmore, C.M. and Kuperwasser, C. (2008) Human breast cancer cell lines contain stem-like cells that self-renew, give rise to phenotypically diverse progeny and survive chemotherapy. Breast Cancer Res. 10, R25.
    • (2008) Breast Cancer Res. , vol.10
    • Fillmore, C.M.1    Kuperwasser, C.2
  • 146
    • 46249092307 scopus 로고    scopus 로고
    • The hepatic stem cell niche: Identification by label-retaining cell assay
    • DOI 10.1002/hep.22218
    • Kuwahara, R., Kofman, A.V., Landis, C.S., Swenson, E.S., Barendswaard, E., and Theise, N.D. (2008) The hepatic stem cell niche: identification by label-retaining cell assay. Hepatology 47, 1994-2002. (Pubitemid 351945566)
    • (2008) Hepatology , vol.47 , Issue.6 , pp. 1994-2002
    • Kuwahara, R.1    Kofman, A.V.2    Landis, C.S.3    Swenson, E.S.4    Barendswaard, E.5    Theise, N.D.6
  • 147
    • 79952267491 scopus 로고    scopus 로고
    • Distinct slow-cycling cancer stem-like subpopulation of pancreatic adenocarcinoma cells is maintained in vivo
    • Jennifer, L., Dembinski, L., and Krauss, S. (2010) Distinct slow-cycling cancer stem-like subpopulation of pancreatic adenocarcinoma cells is maintained in vivo. Cancers, 2, 2011-2025.
    • (2010) Cancers , vol.2 , pp. 2011-2025
    • Jennifer, L.1    Dembinski, L.2    Krauss, S.3
  • 148
    • 73649107330 scopus 로고    scopus 로고
    • Cancer stem cells and aneuploid populations within developing tumors are the major determinants of tumor dormancy
    • Kusumbe, A.P. and Bapat, S.A. (2009) Cancer stem cells and aneuploid populations within developing tumors are the major determinants of tumor dormancy. Cancer Res. 69(24), 9245-9253.
    • (2009) Cancer Res. , vol.69 , Issue.24 , pp. 9245-9253
    • Kusumbe, A.P.1    Bapat, S.A.2
  • 150
    • 0033559945 scopus 로고    scopus 로고
    • Hematopoietic stem cell tracking in vivo: A comparison of short-term and long-term repopulating cells
    • Lanzkron, S.M., Collector, M.I., and Sharkis, S.J. (1999) Hematopoietic stem cell tracking in vivo: a comparison of short-term and long-term repopulating cells. Blood 93, 1916-1921. (Pubitemid 29128493)
    • (1999) Blood , vol.93 , Issue.6 , pp. 1916-1921
    • Lanzkron, S.M.1    Collector, M.I.2    Sharkis, S.J.3
  • 151
    • 26844490483 scopus 로고    scopus 로고
    • Usefulness of PKH fluorescent labelling to study leukemic cell proliferation with various cytostatic drugs or acetyl tetrapeptide-AcSDKP
    • Boutonnat, J., Faussat, A.M., Marie, J.P., Bignon, J., Wdzieczak-Bakala, J., Barbier, M., Thierry, J., Ronot, X., and Colle, P.E. (2005) Usefulness of PKH fluorescent labelling to study leukemic cell proliferation with various cytostatic drugs or acetyl tetrapeptide-AcSDKP. BMC Cancer 5, 120.
    • (2005) BMC Cancer , vol.5 , pp. 120
    • Boutonnat, J.1    Faussat, A.M.2    Marie, J.P.3    Bignon, J.4    Wdzieczak-Bakala, J.5    Barbier, M.6    Thierry, J.7    Ronot, X.8    Colle, P.E.9
  • 152
    • 19644373254 scopus 로고    scopus 로고
    • Wnt signaling in disease and in development
    • Nusse, R. (2005) Wnt signaling in disease and in development. Cell Res. 15, 28-32.
    • (2005) Cell Res. , vol.15 , pp. 28-32
    • Nusse, R.1
  • 153
    • 17244376814 scopus 로고    scopus 로고
    • Wnt signalling in stem cells and cancer
    • Reya, T. and Clevers, H. (2005) Wnt signalling in stem cells and cancer. Nature 434, 349-354.
    • (2005) Nature , vol.434 , pp. 349-354
    • Reya, T.1    Clevers, H.2
  • 154
    • 0033521967 scopus 로고    scopus 로고
    • Female development in mammals is regulated by Wnt-4 signaling
    • Vainio, S., Heikkilä, M., Kispert, A., Chin, N., and McMahon, A.P. (1999) Female development in mammals is regulated by Wnt-4 signaling. Nature 397, 405-409.
    • (1999) Nature , vol.397 , pp. 405-409
    • Vainio, S.1    Heikkilä, M.2    Kispert, A.3    Chin, N.4    McMahon, A.P.5
  • 158
    • 0032813907 scopus 로고    scopus 로고
    • Beta-Catenin expression pattern in stage I and II ovarian carcinomas: Relationship with beta-catenin gene mutations, clinicopathological features, and clinical outcome
    • Gamallo, C., Palacios, J., Moreno, G., Calvo de Mora, J., Suarez, A., and Armas, A. (1999) Beta-catenin expression pattern in stage I and II ovarian carcinomas: relationship with beta-catenin gene mutations, clinicopathological features, and clinical outcome. Am. J. Pathol. 155, 527-536. (Pubitemid 29370402)
    • (1999) American Journal of Pathology , vol.155 , Issue.2 , pp. 527-536
    • Gamallo, C.1    Palacios, J.2    Moreno, G.3    De Mora, J.C.4    Suarez, A.5    Armas, A.6
  • 160
  • 164
    • 0035028066 scopus 로고    scopus 로고
    • Frequent nuclear beta-catenin accumulation and associated mutations in endometrioid-type endometrial and ovarian carcinomas with squamous differentiation
    • Saegusa, M. and Okayasu, I. (2001) Frequent nuclear beta-catenin accumulation and associated mutations in endometrioid-type endometrial and ovarian carcinomas with squamous differentiation. J. Pathol. 194, 59-67.
    • (2001) J. Pathol. , vol.194 , pp. 59-67
    • Saegusa, M.1    Okayasu, I.2
  • 167
    • 32944462571 scopus 로고    scopus 로고
    • FGF9 has oncogenic activity and is a downstream target of Wnt signaling ovarian endometrioid adenocarcinomas
    • Hendrix, N., Wu, R., Kuick, R., Schwartz, D.R., Fearon, E.R., and Cho, K.R. (2006) FGF9 has oncogenic activity and is a downstream target of Wnt signaling ovarian endometrioid adenocarcinomas. Cancer Res. 66, 1354-1362.
    • (2006) Cancer Res. , vol.66 , pp. 1354-1362
    • Hendrix, N.1    Wu, R.2    Kuick, R.3    Schwartz, D.R.4    Fearon, E.R.5    Cho, K.R.6
  • 169
    • 73949131656 scopus 로고    scopus 로고
    • Low membranous expression of b-catenin and high mitotic count predict poor prognosis in endometrioid carcinoma of the ovary
    • Rosen, D.G., Zhang, Z., Chang, B., Wang, X., Lin, E., and Liu, J. (2010) Low membranous expression of b-catenin and high mitotic count predict poor prognosis in endometrioid carcinoma of the ovary. Mod. Pathol. 23, 113-122.
    • (2010) Mod. Pathol. , vol.23 , pp. 113-122
    • Rosen, D.G.1    Zhang, Z.2    Chang, B.3    Wang, X.4    Lin, E.5    Liu, J.6
  • 170
    • 0033709190 scopus 로고    scopus 로고
    • Desert hedgehog (Dhh) gene is required in the mouse testis for formation of adult-type Leydig cells and normal development of peritubular cells and seminiferous tubules
    • Clark, A.M., Garland, K.K., and Russell, L.D. (2000) Desert hedgehog (Dhh) gene is required in the mouse testis for formation of adult-type Leydig cells and normal development of peritubular cells and seminiferous tubules. Biol. Reprod. 63, 1825-1838.
    • (2000) Biol. Reprod. , vol.63 , pp. 1825-1838
    • Clark, A.M.1    Garland, K.K.2    Russell, L.D.3
  • 171
    • 0035881926 scopus 로고    scopus 로고
    • Manifestation of the limb prepattern: Limb development in the absence of sonic hedgehog function
    • DOI 10.1006/dbio.2001.0346
    • Chiang, C., Litingtung, Y., Harris, M.P., Simandl, B.K., Li, Y., Beachy, P.A., and Fallon, J.F. (2001) Manifestation of the limb prepattern: limb development in the absence of sonic hedgehog function. Dev. Biol. 236, 421-435. (Pubitemid 32756995)
    • (2001) Developmental Biology , vol.236 , Issue.2 , pp. 421-435
    • Chiang, C.1    Litingtung, Y.2    Harris, M.P.3    Simandl, B.K.4    Li, Y.5    Beachy, P.A.6    Fallon, J.F.7
  • 173
    • 0037007146 scopus 로고    scopus 로고
    • In vitro cartilage formation by human adult stem cells from bone marrow stroma defines the sequence of cellular and molecular events during chondrogenesis
    • DOI 10.1073/pnas.052716199
    • Sekiya, I., Vuoristo, J.T., Larson, B.L., and Prockop, D.J. (2002) In vitro cartilage formation by human adult stem cells from bone marrow stroma defines the sequence of cellular and molecular events during chondrogenesis. Proc. Natl. Acad. Sci. U. S. A. 99, 4397-4402. (Pubitemid 34285996)
    • (2002) Proceedings of the National Academy of Sciences of the United States of America , vol.99 , Issue.7 , pp. 4397-4402
    • Sekiya, I.1    Vuoristo, J.T.2    Larson, B.L.3    Prockop, D.J.4
  • 175
    • 21344436821 scopus 로고    scopus 로고
    • Beta-catenin and hedgehog signal strength can specify number and location of hair follicles in adult epidermis without recruitment of bulge stem cells
    • DOI 10.1016/j.devcel.2005.04.013, PII S1534580705001681
    • Silva-Vargas, V., Lo Celso, C., Giangreco, A., Ofstad, T., Prowse, D.M., Braun, K.M, and Watt, F.M. (2005) Beta-catenin and Hedgehog signal strength can specify number and location of hair follicles in adult epidermis without recruitment of bulge stem cells. Dev. Cell 9, 121-131. (Pubitemid 40903665)
    • (2005) Developmental Cell , vol.9 , Issue.1 , pp. 121-131
    • Silva-Vargas, V.1    Lo, C.C.2    Giangreco, A.3    Ofstad, T.4    Prowse, D.M.5    Braun, K.M.6    Watt, F.M.7
  • 176
    • 27144487469 scopus 로고    scopus 로고
    • In vivo analysis of quiescent adult neural stem cells responding to Sonic hedgehog
    • DOI 10.1038/nature03994, PII N03994
    • Ahn, S. and Joyner, A.L. (2005) In vivo analysis of quiescent adult neural stem cells responding to Sonic hedgehog. Nature 437, 894-897. (Pubitemid 41486765)
    • (2005) Nature , vol.437 , Issue.7060 , pp. 894-897
    • Ahn, S.1    Joyner, A.L.2
  • 177
    • 33745728170 scopus 로고    scopus 로고
    • Hedgehog signaling and Bmi-1 regulate self-renewal of normal and malignant human mammary stem cells
    • Liu, S., Dontu, G., Mantle, I.D., Patel, S., Ahn, N.S., Jackson, K.W., Suri, P., and Wicha, M.S. (2006) Hedgehog signaling and Bmi-1 regulate self-renewal of normal and malignant human mammary stem cells. Cancer Res. 66, 6063-6071.
    • (2006) Cancer Res. , vol.66 , pp. 6063-6071
    • Liu, S.1    Dontu, G.2    Mantle, I.D.3    Patel, S.4    Ahn, N.S.5    Jackson, K.W.6    Suri, P.7    Wicha, M.S.8
  • 178
    • 1042298768 scopus 로고    scopus 로고
    • Regulation of Hedgehog signaling: A complex story
    • DOI 10.1016/j.bcp.2004.01.002
    • Ogden, S.K., Ascano, M.J., Stegman, M.A., and Robbins, D.J. (2004) Regulation of Hedgehog signalling: a complex story. Biochem. Pharmacol. 67, 805-814. (Pubitemid 38201626)
    • (2004) Biochemical Pharmacology , vol.67 , Issue.5 , pp. 805-814
    • Ogden, S.K.1    Ascano Jr., M.2    Stegman, M.A.3    Robbins, D.J.4
  • 179
    • 0035902140 scopus 로고    scopus 로고
    • The Hedgehog and Wnt signalling pathways in cancer
    • DOI 10.1038/35077219
    • Taipale, J. and Beachy, P.A. (2001) The Hedgehog and Wnt signalling pathways in cancer. Nature 411, 349-354. (Pubitemid 32467044)
    • (2001) Nature , vol.411 , Issue.6835 , pp. 349-354
    • Taipale, J.1    Beachy, P.A.2
  • 183
    • 33751264968 scopus 로고    scopus 로고
    • Synthetic microRNA designed to target glioma-associated antigen 1 transcription factor inhibits division and induces late apoptosis in pancreatic tumor cells
    • DOI 10.1158/1078-0432.CCR-06-0588
    • Tsuda, N., Ishiyama, S., Li, Y., Ioannides, C.G., Abbruzzese, J.L., and Chang, D.Z. (2006) Synthetic microRNA designed to target glioma-associated antigen 1 transcription factor inhibits division and induces late apoptosis in pancreatic tumor cells. Clin. Cancer Res. 12, 6557-6564. (Pubitemid 44799731)
    • (2006) Clinical Cancer Research , vol.12 , Issue.21 , pp. 6557-6564
    • Tsuda, N.1    Ishiyama, S.2    Li, Y.3    Ioannides, C.G.4    Abbruzzese, J.L.5    Chang, D.Z.6
  • 184
    • 33751209187 scopus 로고    scopus 로고
    • Hedgehog/Ras interactions regulate early stages of pancreatic cancer
    • DOI 10.1101/gad.1470806
    • Pasca di Magliano, M., Sekine, S., Ermilov, A., Ferris, J., Dlugosz, A.A., and Hebrok, M. (2006) Hedgehog/Ras interactions regulate early stages of pancreatic cancer. Genes Dev. 20, 3161-3173. (Pubitemid 44790630)
    • (2006) Genes and Development , vol.20 , Issue.22 , pp. 3161-3173
    • Di, M.M.P.1    Sekine, S.2    Ermilov, A.3    Ferris, J.4    Dlugosz, A.A.5    Hebrok, M.6
  • 186
    • 58949100355 scopus 로고    scopus 로고
    • Aberrant activation of hedgehog signaling pathway in ovarian cancers: Effect on prognosis, cell invasion and differentiation
    • Liao, X., Siu, M.K., Au, C.W., Wong, E.S., Chan, H.Y., Ip, P.P., Ngan, H.Y., and Cheung, A.N. (2009) Aberrant activation of hedgehog signaling pathway in ovarian cancers: effect on prognosis, cell invasion and differentiation. Carcinogenesis 30, 131-140.
    • (2009) Carcinogenesis , vol.30 , pp. 131-140
    • Liao, X.1    Siu, M.K.2    Au, C.W.3    Wong, E.S.4    Chan, H.Y.5    Ip, P.P.6    Ngan, H.Y.7    Cheung, A.N.8
  • 188
    • 33751337806 scopus 로고    scopus 로고
    • Hedgehog signal pathway is activated in ovarian carcinomas, correlating with cell proliferation: It's inhibition leads to growth suppression and apoptosis
    • DOI 10.1111/j.1349-7006.2006.00353.x
    • Chen, X., Horiuchi, A., Kikuchi, N., Osada, R., Yoshida, J., Shiozawa, T., and Konishi, I. (2007) Hedgehog signal pathway is activated in ovarian carcinomas, correlating with cell proliferation: it's inhibition leads to growth suppression and apoptosis. Cancer Sci. 98, 68-76. (Pubitemid 44803922)
    • (2007) Cancer Science , vol.98 , Issue.1 , pp. 68-76
    • Chen, X.1    Horiuchi, A.2    Kikuchi, N.3    Osada, R.4    Yoshida, J.5    Shiozawa, T.6    Konishi, I.7
  • 191
    • 33751549095 scopus 로고    scopus 로고
    • Targeting the Hedgehog pathway in cancer
    • DOI 10.1038/nrd2086, PII NRD2086
    • Rubin, L.L. and de Sauvage, F.J. (2006) Targeting the Hedgehog pathway in cancer. Nat. Rev. Drug Discov. 5, 1026-1033. (Pubitemid 44835129)
    • (2006) Nature Reviews Drug Discovery , vol.5 , Issue.12 , pp. 1026-1033
    • Rubin, L.L.1    De Sauvage, F.J.2
  • 192
    • 71549129295 scopus 로고    scopus 로고
    • Activation of hedgehog signaling is not a frequent event in ovarian cancers
    • Yang, L., He, J., Huang, S., Zhang, X., Bian, Y., He, N., Zhang, H., and Xie, J. (2009) Activation of hedgehog signaling is not a frequent event in ovarian cancers. Mol. Cancer 8, 112.
    • (2009) Mol. Cancer , vol.8 , pp. 112
    • Yang, L.1    He, J.2    Huang, S.3    Zhang, X.4    Bian, Y.5    He, N.6    Zhang, H.7    Xie, J.8
  • 194
    • 0028948811 scopus 로고
    • The product of hedgehog autoproteolytic cleavage active in local and long-range signaling
    • Porter, J.A., von Kessler, D.P., Ekker, S.C., Young, K.E., Lee, J.J., Moses, K., and Beachy, P.A. (1995) The product of hedgehog autoproteolytic cleavage active in local and long-range signaling. Nature 374, 363-366.
    • (1995) Nature , vol.374 , pp. 363-366
    • Porter, J.A.1    Von Kessler, D.P.2    Ekker, S.C.3    Young, K.E.4    Lee, J.J.5    Moses, K.6    Beachy, P.A.7
  • 195
    • 33750686955 scopus 로고    scopus 로고
    • The Hedgehog signaling pathway in cancer
    • DOI 10.1158/1078-0432.CCR-06-1736
    • Evangelista,M., Tian, H., and de Sauvage F.J. (2006) The hedgehog signaling pathway in cancer. Clin. Cancer Res. 12, 5924-5928. (Pubitemid 44703749)
    • (2006) Clinical Cancer Research , vol.12 , Issue.20 PART 1 , pp. 5924-5928
    • Evangelista, M.1    Tian, H.2    De Sauvage, F.J.3
  • 197
    • 69249106131 scopus 로고    scopus 로고
    • Ovarian cancer: Emerging concept on cancer stem cells
    • Ponnusamy, M.P. and Batra, S.K. (2008) Ovarian cancer: emerging concept on cancer stem cells. J. Ovar. Res. 1, 4.
    • (2008) J. Ovar. Res. , vol.1 , pp. 4
    • Ponnusamy, M.P.1    Batra, S.K.2
  • 198
    • 0033617522 scopus 로고    scopus 로고
    • Notch signaling: Cell fate control and signal integration in development
    • DOI 10.1126/science.284.5415.770
    • Artavanis-Tsakonas, S., Rand, M.D., and Lake, R.J. (1999) Notch signaling: cell fate control and signal integration in development. Science 284, 770-776. (Pubitemid 29291335)
    • (1999) Science , vol.284 , Issue.5415 , pp. 770-776
    • Artavanis-Tsakonas, S.1    Rand, M.D.2    Lake, R.J.3
  • 199
    • 85047699421 scopus 로고    scopus 로고
    • Vertebrate hairy and Enhancer of split related proteins: Transcriptional repressors regulating cellular differentiation and embryonic patterning
    • DOI 10.1038/sj/onc/1205094
    • Davis, R.L. and Turner, D.L. (2001) Vertebrate hairy and Enhancer of split related proteins: transcriptional repressors regulating cellular differentiation and embryonic patterning. Oncogene 20, 8342-8357 (Pubitemid 34121905)
    • (2001) Oncogene , vol.20 , Issue.58 REV. ISS. 8 , pp. 8342-8357
    • Davis, R.L.1    Turner, D.L.2
  • 200
    • 0034778258 scopus 로고    scopus 로고
    • Notch signaling is required for arterial-venous differentiation during embryonic vascular development
    • Lawson, N.D., Scheer, N., Pham, V.N., Kim, C.H., Chitnis, A.B., Campos-Ortega, J.A., and Weinstein, B.M. (2001) Notch signaling is required for arterial-venous differentiation during embryonic vascular development. Development 128, 3675-3683. (Pubitemid 32998917)
    • (2001) Development , vol.128 , Issue.19 , pp. 3675-3683
    • Lawson, N.D.1    Scheer, N.2    Pham, V.N.3    Kim, C.-H.4    Chitnis, A.B.5    Campos-Ortega, J.A.6    Weinstein, B.M.7
  • 210
  • 211
    • 48649090161 scopus 로고    scopus 로고
    • Jagged-1 and Notch3 juxtacrine loop regulates ovarian tumor growth and adhesion
    • Choi, J.H., Park, J.T., Davidson, B., Morin, P.J., Shih, I.M., and Wang, T.L. (2008) Jagged-1 and Notch3 juxtacrine loop regulates ovarian tumor growth and adhesion. Cancer Res. 68, 5716-5723.
    • (2008) Cancer Res. , vol.68 , pp. 5716-5723
    • Choi, J.H.1    Park, J.T.2    Davidson, B.3    Morin, P.J.4    Shih, I.M.5    Wang, T.L.6
  • 212
    • 27144504699 scopus 로고    scopus 로고
    • The Notch pathway in ovarian carcinomas and adenomas
    • DOI 10.1038/sj.bjc.6602719, PII 6602719
    • Hopfer, O., Zwahlen, D., Fey, M.F., and Aebi, S. (2005) The Notch pathway in ovarian carcinomas and adenomas. Br. J. Cancer 93, 709-718. (Pubitemid 41486463)
    • (2005) British Journal of Cancer , vol.93 , Issue.6 , pp. 709-718
    • Hopfer, O.1    Zwahlen, D.2    Fey, M.F.3    Aebi, S.4
  • 215
    • 77249142228 scopus 로고    scopus 로고
    • Down-regulation of Notch1 by gamma-secretase inhibition contributes to cell growth inhibition and apoptosis in ovarian cancer cells A2780
    • Wang, M., Wu, L., Wang, L., and Xin, X. (2010) Down-regulation of Notch1 by gamma-secretase inhibition contributes to cell growth inhibition and apoptosis in ovarian cancer cells A2780. Biochem. Biophys. Res. Commun. 393, 144-149.
    • (2010) Biochem. Biophys. Res. Commun. , vol.393 , pp. 144-149
    • Wang, M.1    Wu, L.2    Wang, L.3    Xin, X.4
  • 216
    • 53849106782 scopus 로고    scopus 로고
    • VEGF and Delta-Notch: Interacting signalling pathways in tumor angiogenesis
    • Thurston, G., and Kitajewski, J. (2008) VEGF and Delta-Notch: interacting signalling pathways in tumor angiogenesis. Br. J. Cancer 99, 1204-1209.
    • (2008) Br. J. Cancer , vol.99 , pp. 1204-1209
    • Thurston, G.1    Kitajewski, J.2
  • 217
    • 25444506836 scopus 로고    scopus 로고
    • Up-regulation of delta-like 4 ligand in human tumor vasculature and the role of basal expression in endothelial cell function
    • DOI 10.1158/0008-5472.CAN-05-1208
    • Patel, N.S., Li, J.L., Generali, D., Poulsom, R., Cranston. D.W., and Harris, A.L. (2005) Up-regulation of delta-like 4 ligand in human tumor vasculature and the role of basal expression in endothelial cell function. Cancer Res. 65, 8690-8697. (Pubitemid 41377356)
    • (2005) Cancer Research , vol.65 , Issue.19 , pp. 8690-8697
    • Patel, N.S.1    Li, J.-L.2    Generali, D.3    Poulsom, R.4    Cranston, D.W.5    Harris, A.L.6
  • 219
    • 33847735810 scopus 로고    scopus 로고
    • Gene alterations identified by expression profiling in tumor-associated endothelial cells from invasive ovarian carcinoma
    • DOI 10.1158/0008-5472.CAN-06-3700
    • Lu, C., Bonome, T., Li, Y., Kamat, A.A., Han, L.Y., Schmandt, R., Coleman, R.L., Gershenson, D.M., Jaffe, R.B., Birrer, M.J., and Sood, A.K. (2007) Gene alterations identified by expression profiling in tumor-associated endothelial cells from invasive ovarian carcinoma. Cancer Res. 67, 1757-1768. (Pubitemid 46383403)
    • (2007) Cancer Research , vol.67 , Issue.4 , pp. 1757-1768
    • Lu, C.1    Bonome, T.2    Li, Y.3    Kamat, A.A.4    Han, L.Y.5    Schmandt, R.6    Coleman, R.L.7    Gershenson, D.M.8    Jaffe, R.B.9    Birrer, M.J.10    Sood, A.K.11
  • 220
    • 0038636459 scopus 로고    scopus 로고
    • RRM1-induced metastasis suppression through PTEN-regulated pathways
    • DOI 10.1038/sj.onc.1206232
    • Gautam, A., Li, Z.R., and Bepler, G. (2003) RRM1-induced metastasis suppression through PTEN-regulated pathways. Oncogene 22, 2135-2142. (Pubitemid 36539563)
    • (2003) Oncogene , vol.22 , Issue.14 , pp. 2135-2142
    • Gautam, A.1    Li, Z.-R.2    Bepler, G.3
  • 222
    • 0842308265 scopus 로고    scopus 로고
    • PTEN mutations are common in sporadic microsatellite stable colorectal cancer
    • DOI 10.1038/sj.onc.1207059
    • Nassif, N.T., Lobo, G.P., Wu, X., Henderson, C.J., Morrison, C.D., Eng, C., Jalaludin, B., and Segelov, E. (2004) PTEN mutations are common in sporadic microsatellite stable colorectal cancer. Oncogene 23, 617-628. (Pubitemid 38175018)
    • (2004) Oncogene , vol.23 , Issue.2 , pp. 617-628
    • Nassif, N.T.1    Lobo, G.P.2    Wu, X.3    Henderson, C.J.A.4    Morrison, C.D.5    Eng, C.6    Jalaludin, B.7    Segelov, E.8
  • 225
    • 5144226211 scopus 로고    scopus 로고
    • PTEN activation contributes to tumor inhibition by trastuzumab, and loss of PTEN predicts trastuzumab resistance in patients
    • DOI 10.1016/j.ccr.2004.06.022, PII S1535610804002107
    • Nagata, Y., Lan, K.H., Zhou, X., Tan, M., Esteva, F.J., Sahin, A.A., Klos, K.S., Li, P., Monia, B.P., Nguyen, N.T., Hortobagyi, G.N., Hung, M.C., and Yu, D. (2004) PTEN activation contributes to tumor inhibition by trastuzumab, and loss of PTEN predicts trastuzumab resistance in patients. Cancer Cell 6, 117-127. (Pubitemid 39485684)
    • (2004) Cancer Cell , vol.6 , Issue.2 , pp. 117-127
    • Nagata, Y.1    Lan, K.-H.2    Zhou, X.3    Tan, M.4    Esteva, F.J.5    Sahin, A.A.6    Klos, K.S.7    Li, P.8    Monia, B.P.9    Nguyen, N.T.10    Hortobagyi, G.N.11    Hung, M.-C.12    Yu, D.13
  • 226
    • 77951667289 scopus 로고    scopus 로고
    • Prognostic value of microsatellite instability (MSI) and PTEN expression in women with endometrial cancer: Results from studies of the NCIC Clinical Trials Group (NCIC CTG)
    • Mackay, H.J., Gallinger, S., Tsao, M.S., McLachlin, C.M., Tu, D., Keiser, K., Eisenhauer, E.A., and Oza, A.M. (2010) Prognostic value of microsatellite instability (MSI) and PTEN expression in women with endometrial cancer: results from studies of the NCIC Clinical Trials Group (NCIC CTG). Eur. J. Cancer 46, 1365-1373.
    • (2010) Eur. J. Cancer , vol.46 , pp. 1365-1373
    • Mackay, H.J.1    Gallinger, S.2    Tsao, M.S.3    McLachlin, C.M.4    Tu, D.5    Keiser, K.6    Eisenhauer, E.A.7    Oza, A.M.8
  • 228
    • 33644499133 scopus 로고    scopus 로고
    • Pten deficiency activates distinct downstream signaling pathways in a tissue-specific manner
    • Yoo, L.I., Liu, D.W., Vu, S.L., Bronson, R.T., Wu, H., and Yuan, J. (2006) Pten deficiency activates distinct downstream signaling pathways in a tissue-specific manner. Cancer Res. 66, 1929-1939.
    • (2006) Cancer Res. , vol.66 , pp. 1929-1939
    • Yoo, L.I.1    Liu, D.W.2    Vu, S.L.3    Bronson, R.T.4    Wu, H.5    Yuan, J.6
  • 229
    • 66449115036 scopus 로고    scopus 로고
    • PTEN, stem cells, and cancer stem cells
    • Hill, R. and Wu, H. (2009) PTEN, stem cells, and cancer stem cells. J. Biol. Chem. 284, 11755-11759.
    • (2009) J. Biol. Chem. , vol.284 , pp. 11755-11759
    • Hill, R.1    Wu, H.2
  • 230
    • 33746990186 scopus 로고    scopus 로고
    • Mechanistic Insights into Maintenance of High p53 Acetylation by PTEN
    • DOI 10.1016/j.molcel.2006.06.028, PII S1097276506004564
    • Li, A.G., Piluso, L.G., Cai, X., Wei, G., Sellers, W.R., and Liu, X. (2006) Mechanistic insights into maintenance of high p53 acetylation by PTEN. Mol. Cell 23, 575-587. (Pubitemid 44205492)
    • (2006) Molecular Cell , vol.23 , Issue.4 , pp. 575-587
    • Li, A.G.1    Piluso, L.G.2    Cai, X.3    Wei, G.4    Sellers, W.R.5    Liu, X.6
  • 232
    • 0034671218 scopus 로고    scopus 로고
    • Loss of heterozygosity on 10q23.3 and mutation of the tumor suppressor gene PTEN in benign endometrial cyst of the ovary: Possible sequence progression from benign endometrial cyst to endometrioid carcinoma and clear cell carcinoma of the ovary
    • Sato, N., Tsunoda, H., Nishida, M., Morishita, Y., Takimoto, Y., Kubo, T., and Noguchi, M. (2000) Loss of heterozygosity on 10q23.3 and mutation of the tumor suppressor gene PTEN in benign endometrial cyst of the ovary: possible sequence progression from benign endometrial cyst to endometrioid carcinoma and clear cell carcinoma of the ovary. Cancer Res. 60, 7052-7056. (Pubitemid 32059184)
    • (2000) Cancer Research , vol.60 , Issue.24 , pp. 7052-7056
    • Sato, N.1    Tsunoda, H.2    Nishida, M.3    Morishita, Y.4    Takimoto, Y.5    Kubo, T.6    Noguchi, M.7
  • 234
    • 0035266318 scopus 로고    scopus 로고
    • XIAP regulates Akt activity and caspase-3-dependent cleavage during cisplatin-induced apoptosis in human ovarian epithelial cancer cells
    • Asselin, E., Mills, G.B., and Tsang, B.K. (2001) XIAP regulates Akt activity and caspase-3-dependent cleavage during cisplatin- induced apoptosis in human ovarian epithelial cancer cells. Cancer Res. 61, 1862-1868. (Pubitemid 32692000)
    • (2001) Cancer Research , vol.61 , Issue.5 , pp. 1862-1868
    • Asselin, E.1    Mills, G.B.2    Tsang, B.K.3
  • 235
    • 0242610903 scopus 로고    scopus 로고
    • P53 Is a Determinant of X-Linked Inhibitor of Apoptosis Protein/Akt-Mediated Chemoresistance in Human Ovarian Cancer Cells
    • Fraser, M., Leung, B.M., Yan, X., Dan, H.C., Cheng, J.Q., and Tsang, B.K. (2003) p53 is a determinant of X-linked inhibitor of apoptosis protein/Akt-mediated chemoresistance in human ovarian cancer cells. Cancer Res. 63, 7081-7088. (Pubitemid 37413443)
    • (2003) Cancer Research , vol.63 , Issue.21 , pp. 7081-7088
    • Fraser, M.1    Leung, B.M.2    Yan, X.3    Dan, H.C.4    Cheng, J.Q.5    Tsang, B.K.6
  • 236
    • 0034616945 scopus 로고    scopus 로고
    • Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition
    • Du, C., Fang, M., Li, Y., Li, L., and Wang, X. (2000) Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition. Cell 102, 33-42.
    • (2000) Cell , vol.102 , pp. 33-42
    • Du, C.1    Fang, M.2    Li, Y.3    Li, L.4    Wang, X.5
  • 237
    • 33645516362 scopus 로고    scopus 로고
    • Akt-mediated cisplatin resistance in ovarian cancer: Modulation of p53 action on caspase-dependent mitochondrial death pathway
    • Yang, X., Fraser, M., Moll, U.M., Basak, A., and Tsang, B.K. (2006) Akt-mediated cisplatin resistance in ovarian cancer: modulation of p53 action on caspase-dependent mitochondrial death pathway. Cancer Res. 66, 3126-3136.
    • (2006) Cancer Res. , vol.66 , pp. 3126-3136
    • Yang, X.1    Fraser, M.2    Moll, U.M.3    Basak, A.4    Tsang, B.K.5
  • 238
    • 4344602002 scopus 로고    scopus 로고
    • The biology and clinical relevance of the PTEN tumor suppressor pathway
    • DOI 10.1200/JCO.2004.02.141
    • Sansal, I. and Sellers, W.S. (2004) The biology and clinical relevance of the PTEN tumor suppressor pathway, J. Clin. Oncol. 22, 2954-2963. (Pubitemid 41079915)
    • (2004) Journal of Clinical Oncology , vol.22 , Issue.14 , pp. 2954-2963
    • Sansal, I.1    Sellers, W.R.2
  • 239
    • 39049086391 scopus 로고    scopus 로고
    • MicroRNA expression profiling in human ovarian cancer: MiR-214 induces cell survival and cisplatin resistance by targeting PTEN
    • DOI 10.1158/0008-5472.CAN-07-2488
    • Yang, H., Kong, W., He, L., Zhao, J.J., O'Donnell, J.D., Wang, J., Wenham, R.M., Coppola, D., Kruk, P.A., Nicosia, S.V., and Cheng, J.Q. (2008) MicroRNA expression profiling in human ovarian cancer: miR-214 induces cell survival and cisplatin resistance by targeting PTEN. Cancer Res. 68, 425-433. (Pubitemid 351380068)
    • (2008) Cancer Research , vol.68 , Issue.2 , pp. 425-433
    • Yang, H.1    Kong, W.2    He, L.3    Zhao, J.-J.4    O'Donnell, J.D.5    Wang, J.6    Wenham, R.M.7    Coppola, D.8    Kruk, P.A.9    Nicosia, S.V.10    Cheng, J.Q.11
  • 240
    • 77953806998 scopus 로고    scopus 로고
    • TWISTing stemness, inflammation and proliferation of epithelial ovarian cancer cells through MIR199A2/214
    • Yin, G., Chen, R., Alvero, A.B., Fu, H.H., Holmberg, J., Glackin, C., Rutherford, T., and Mor, G. (2010) TWISTing stemness, inflammation and proliferation of epithelial ovarian cancer cells through MIR199A2/214. Oncogene 29, 3545-3553.
    • (2010) Oncogene , vol.29 , pp. 3545-3553
    • Yin, G.1    Chen, R.2    Alvero, A.B.3    Fu, H.H.4    Holmberg, J.5    Glackin, C.6    Rutherford, T.7    Mor, G.8
  • 242
    • 67650487925 scopus 로고    scopus 로고
    • Clinical practice-screening for ovarian cancer
    • Clarke-Pearson, D.L. (2009) Clinical practice-screening for ovarian cancer. N. Engl. J. Med. 361 (2), 170-177.
    • (2009) N. Engl. J. Med. , vol.361 , Issue.2 , pp. 170-177
    • Clarke-Pearson, D.L.1
  • 245
    • 33744917817 scopus 로고    scopus 로고
    • Tetraploidy/aneuploidy and stem cells in cancer promotion: The role of chromosome passenger proteins
    • DOI 10.1002/jcp.20565
    • Nguyen, H.G. and Ravid, K. (2006) Tetraploidy/aneuploidy and stem cells in cancer promotion: the role of chromosome passenger proteins. J. Cell Physiol. 208, 12-22. (Pubitemid 43848985)
    • (2006) Journal of Cellular Physiology , vol.208 , Issue.1 , pp. 12-22
    • Nguyen, H.G.1    Ravid, K.2
  • 246
    • 35948943082 scopus 로고    scopus 로고
    • Aneuploidy: Instigator and inhibitor of tumorigenesis
    • DOI 10.1158/0008-5472.CAN-07-2266
    • Weaver, B.A. and Cleveland, D.W. (2007) Aneuploidy: instigator and inhibitor of tumorigenesis. Cancer Res. 67, 10103-10105. (Pubitemid 350070779)
    • (2007) Cancer Research , vol.67 , Issue.21 , pp. 10103-10105
    • Weaver, B.A.A.1    Cleveland, D.W.2
  • 250
    • 77956279975 scopus 로고    scopus 로고
    • Cancer stem-like cells can be isolated with drug selection in human ovarian cancer cell line SKOV3
    • Ma, L., Lai, D., Liu, T., Cheng, W., and Guo, L. (2010) Cancer stem-like cells can be isolated with drug selection in human ovarian cancer cell line SKOV3. Acta Biochim. Biophys. Sin. (Shanghai) 42, 593-602.
    • (2010) Acta Biochim. Biophys. Sin. (Shanghai) , vol.42 , pp. 593-602
    • Ma, L.1    Lai, D.2    Liu, T.3    Cheng, W.4    Guo, L.5
  • 251
    • 0036074018 scopus 로고    scopus 로고
    • Mammalian ABC transporters in health and disease
    • DOI 10.1146/annurev.biochem.71.102301.093055
    • Borst, P. and Elferink, R.O. (2002) Mammalian ABC transporters in health and disease. Annu. Rev. Biochem. 71, 537-592. (Pubitemid 34800230)
    • (2002) Annual Review of Biochemistry , vol.71 , pp. 537-592
    • Borst, P.1    Oude, E.R.2
  • 252
    • 0034947674 scopus 로고    scopus 로고
    • From MDR to MXR: New understanding of multidrug resistance systems, their properties and clinical significance
    • Litman, T., Druley, T.E., Stein, W.D., and Bates, S.E. (2001) From MDR to MXR: new understanding of multidrug resistance systems, their properties and clinical significance. Cell Mol. Life Sci. 58, 931-959. (Pubitemid 32652819)
    • (2001) Cellular and Molecular Life Sciences , vol.58 , Issue.7 , pp. 931-959
    • Litman, T.1    Druley, T.E.2    Stein, W.D.3    Bates, S.E.4
  • 253
  • 254
    • 0034917716 scopus 로고    scopus 로고
    • The human ATP-binding cassette (ABC) transporter superfamily
    • DOI 10.1101/gr.GR-1649R
    • Dean, M., Rzhetsky, A., and Allikmets, R. (2001) The human ATP-binding cassette (ABC) transporter superfamily. Genome Res. 11, 1156-1166. (Pubitemid 32677289)
    • (2001) Genome Research , vol.11 , Issue.7 , pp. 1156-1166
    • Dean, M.1    Rzhetsky, A.2    Allikmets, R.3
  • 255
    • 42549124206 scopus 로고    scopus 로고
    • The human ABC transporter pseudogene family: Evidence for transcription and gene-pseudogene interference
    • Piehler, A.P., Hellum, M., Wenzel, J.J., Kaminski, E., Haug, K.B., Kierulf, P., and Kaminski, W.E. (2008) The human ABC transporter pseudogene family: evidence for transcription and gene-pseudogene interference. BMC Genomics 9, 165.
    • (2008) BMC Genomics , vol.9 , pp. 165
    • Piehler, A.P.1    Hellum, M.2    Wenzel, J.J.3    Kaminski, E.4    Haug, K.B.5    Kierulf, P.6    Kaminski, W.E.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.