Akt-mediated cisplatin resistance in ovarian cancer: Modulation of p53 action on caspase-dependent mitochondrial death pathway

Cancer Research

Volumn 66, Issue 6, 2006, Pages 3126-3136

  Yang, Xiaokui ^a   Fraser, Michael ^a   Moll, Ute M ^b   Basak, Ajoy ^a   Tsang, Benjamin K ^a  

^a OTTAWA HOSPITAL RESEARCH INSTITUTE   (Canada)

^b STONY BROOK UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE; CISPLATIN; CYTOCHROME C; PROTEIN BCL 2; PROTEIN KINASE B; PROTEIN P53; SECOND MITOCHONDRIAL ACTIVATOR OF CASPASE; SERINE PROTEINASE OMI;

APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CONTROLLED STUDY; CYTOSOL; DRUG RESISTANCE; DRUG SENSITIZATION; ENZYME ACTIVITY; ENZYME INHIBITION; HUMAN; HUMAN CELL; MITOCHONDRION; OVARY CANCER; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN SECRETION; TRANSACTIVATION;

AMINO ACID SEQUENCE; ANTINEOPLASTIC AGENTS; APOPTOSIS; CASPASES; CISPLATIN; DRUG RESISTANCE, NEOPLASM; FEMALE; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MITOCHONDRIA; MITOCHONDRIAL PROTEINS; MOLECULAR SEQUENCE DATA; OVARIAN NEOPLASMS; PROTO-ONCOGENE PROTEINS C-AKT; SERINE ENDOPEPTIDASES; TUMOR SUPPRESSOR PROTEIN P53;

EID: 33645516362     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-05-0425     Document Type: Article

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