Down-regulation of Notch1 by gamma-secretase inhibition contributes to cell growth inhibition and apoptosis in ovarian cancer cells A2780

Biochemical and Biophysical Research Communications

Volumn 393, Issue 1, 2010, Pages 144-149

  Wang, Mingyi ^a   Wu, Liying ^a   Wang, Lin ^a   Xin, Xiaoyan ^a  

^a FOURTH MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Notch signaling; Notch1; Ovarian carcinoma

Indexed keywords

DIPHTHERIA PERTUSSIS TETANUS VACCINE; GAMMA SECRETASE; NOTCH1 RECEPTOR; TRANSCRIPTION FACTOR HES 1;

APOPTOSIS; ARTICLE; CANCER CELL; CELL CYCLE ARREST; CELL CYCLE G0 PHASE; CELL CYCLE G1 PHASE; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL DEATH; CELL GROWTH; COLONY FORMING UNIT; CONTROLLED STUDY; DOSE TIME EFFECT RELATION; DOWN REGULATION; ENZYME INHIBITION; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; FLOW CYTOMETRY; GROWTH INHIBITION; HUMAN; HUMAN CELL; NITROBLUE TETRAZOLIUM TEST; ONCOGENE; OVARY CANCER; PRIORITY JOURNAL; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

AMYLOID PRECURSOR PROTEIN SECRETASES; ANTINEOPLASTIC AGENTS; APOPTOSIS; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; CELL LINE, TUMOR; CELL PROLIFERATION; DIPEPTIDES; FEMALE; HOMEODOMAIN PROTEINS; HUMANS; OVARIAN NEOPLASMS; PROTEASE INHIBITORS; RECEPTOR, NOTCH1;

EID: 77249142228     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2010.01.103     Document Type: Article

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