-
1
-
-
85013312416
-
Tumor angiogenesis: Therapeutic implications
-
Folkman J. Tumor angiogenesis: therapeutic implications. N Engl J Med 1971;285:1182-6.
-
(1971)
N Engl J Med
, vol.285
, pp. 1182-1186
-
-
Folkman, J.1
-
2
-
-
0036359548
-
Hypoxia - A key regulatory factor in tumour growth
-
Harris AL. Hypoxia - a key regulatory factor in tumour growth. Nat Rev Cancer 2002;2:38-47.
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 38-47
-
-
Harris, A.L.1
-
4
-
-
0030748716
-
The ins and outs of notch signaling
-
Weinmaster G. The ins and outs of notch signaling. Mol Cell Neurosci 1997;9:91-102.
-
(1997)
Mol Cell Neurosci
, vol.9
, pp. 91-102
-
-
Weinmaster, G.1
-
5
-
-
0142259346
-
The role of Notch in tumorigenesis: Oncogene or tumour suppressor?
-
Radtke F, Raj K. The role of Notch in tumorigenesis: oncogene or tumour suppressor? Nat Rev Cancer 2003;3:756-67.
-
(2003)
Nat Rev Cancer
, vol.3
, pp. 756-767
-
-
Radtke, F.1
Raj, K.2
-
6
-
-
0034671686
-
Notch signaling: From the outside in
-
Mumm JS, Kopan R. Notch signaling: from the outside in. Dev Biol 2000;228:151-65.
-
(2000)
Dev Biol
, vol.228
, pp. 151-165
-
-
Mumm, J.S.1
Kopan, R.2
-
7
-
-
0031712743
-
Notch signaling: Direct or what?
-
Weinmaster G. Notch signaling: direct or what? Curr Opin Genet Dev 1998;8:436-42.
-
(1998)
Curr Opin Genet Dev
, vol.8
, pp. 436-442
-
-
Weinmaster, G.1
-
8
-
-
0034610274
-
Members of the HRT family of basic helix-loop-helix proteins act as transcriptional repressors downstream of Notch signaling
-
Nakagawa O, McFadden DG, Nakagawa M, et al. Members of the HRT family of basic helix-loop-helix proteins act as transcriptional repressors downstream of Notch signaling. Proc Natl Acad Sci U S A 2000;97:13655-60.
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, pp. 13655-13660
-
-
Nakagawa, O.1
McFadden, D.G.2
Nakagawa, M.3
-
9
-
-
85047699421
-
Vertebrate hairy and Enhancer of split related proteins: Transcriptional repressors regulating cellular differentiation and embryonic patterning
-
Davis RL, Turner DL. Vertebrate hairy and Enhancer of split related proteins: transcriptional repressors regulating cellular differentiation and embryonic patterning. Oncogene 2001;20:8342-57.
-
(2001)
Oncogene
, vol.20
, pp. 8342-8357
-
-
Davis, R.L.1
Turner, D.L.2
-
10
-
-
0037363922
-
HES and HERP families: Multiple effectors of the Notch signaling pathway
-
Iso T, Kedes L, Hamamori Y. HES and HERP families: multiple effectors of the Notch signaling pathway. J Cell Physiol 2003;194:237-55.
-
(2003)
J Cell Physiol
, vol.194
, pp. 237-255
-
-
Iso, T.1
Kedes, L.2
Hamamori, Y.3
-
12
-
-
5444261424
-
Dosage-sensitive requirement for mouse D114 in artery development
-
Duarte A, Hirashima M, Benedito R, et al. Dosage-sensitive requirement for mouse D114 in artery development. Genes Dev 2004;18:2474-8.
-
(2004)
Genes Dev
, vol.18
, pp. 2474-2478
-
-
Duarte, A.1
Hirashima, M.2
Benedito, R.3
-
13
-
-
5444242184
-
Haploinsufficient lethality and formation of arteriovenous malformations in Notch pathway mutants
-
Krebs LT, Shutter JR, Tanigaki K, Honjo T, Stark KL, Gridley T. Haploinsufficient lethality and formation of arteriovenous malformations in Notch pathway mutants. Genes Dev 2004;18:2469-73.
-
(2004)
Genes Dev
, vol.18
, pp. 2469-2473
-
-
Krebs, L.T.1
Shutter, J.R.2
Tanigaki, K.3
Honjo, T.4
Stark, K.L.5
Gridley, T.6
-
14
-
-
8644290828
-
Haploinsufficiency of delta-like 4 ligand results in embryonic lethality due to major defects in arterial and vascular development
-
Gale NW, Dominguez MG, Noguera I, et al. Haploinsufficiency of delta-like 4 ligand results in embryonic lethality due to major defects in arterial and vascular development. Proc Natl Acad Sci U S A 2004;101:15949-54.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 15949-15954
-
-
Gale, N.W.1
Dominguez, M.G.2
Noguera, I.3
-
16
-
-
0343920277
-
Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele
-
Carmeliet P, Ferreira V, Breier G, et al. Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele. Nature 1996;380:435-9.
-
(1996)
Nature
, vol.380
, pp. 435-439
-
-
Carmeliet, P.1
Ferreira, V.2
Breier, G.3
-
17
-
-
0035753241
-
Delta4, an endothelial specific notch ligand expressed at sites of physiological and tumor angiogenesis
-
Mailhos C, Modlich U, Lewis J, Harris A, Bicknell R, Ish-Horowicz D. Delta4, an endothelial specific notch ligand expressed at sites of physiological and tumor angiogenesis. Differentiation 2001;69:135-44.
-
(2001)
Differentiation
, vol.69
, pp. 135-144
-
-
Mailhos, C.1
Modlich, U.2
Lewis, J.3
Harris, A.4
Bicknell, R.5
Ish-Horowicz, D.6
-
18
-
-
8844262579
-
Periodic delta-like 4 expression in developing retinal arteries
-
Claxton S, Fruttiger M. Periodic delta-like 4 expression in developing retinal arteries. Gene Expr Patterns 2004;5:123-7.
-
(2004)
Gene Expr Patterns
, vol.5
, pp. 123-127
-
-
Claxton, S.1
Fruttiger, M.2
-
19
-
-
0035895269
-
Conditional immortalization of freshly isolated human mammary fibroblasts and endothelial cells
-
O'Hare MJ, Bond J, Clarke C, et al. Conditional immortalization of freshly isolated human mammary fibroblasts and endothelial cells. Proc Natl Acad Sci USA 2001;98:646-51.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 646-651
-
-
O'Hare, M.J.1
Bond, J.2
Clarke, C.3
-
20
-
-
1642475672
-
RNA interference in mammalian cell culture: Design, executin and analysis of the siRNA effect
-
Brown D, Jarvis R, Pallotta V, Byrom M, Ford L. RNA interference in mammalian cell culture: design, executin and analysis of the siRNA effect. Ambion TechNotes 2002;9:3-5.
-
(2002)
Ambion TechNotes
, vol.9
, pp. 3-5
-
-
Brown, D.1
Jarvis, R.2
Pallotta, V.3
Byrom, M.4
Ford, L.5
-
21
-
-
17344392308
-
A new mathematical model for relative quantification in real-time RT-PCR
-
Pfaffl MW. A new mathematical model for relative quantification in real-time RT-PCR. Nucleic Acids Res 2001;29:e45.
-
(2001)
Nucleic Acids Res
, vol.29
-
-
Pfaffl, M.W.1
-
22
-
-
4344699403
-
Role of carbonic anhydrase IX in human tumor cell growth, survival, and invasion
-
Robertson N, Potter C, Harris AL. Role of carbonic anhydrase IX in human tumor cell growth, survival, and invasion. Cancer Res 2004;64:6160-5.
-
(2004)
Cancer Res
, vol.64
, pp. 6160-6165
-
-
Robertson, N.1
Potter, C.2
Harris, A.L.3
-
23
-
-
3042818667
-
Inhibition of human vascular endothelial cells proliferation by terbinafine
-
Ho PY, Liang YC, Ho YS, Chen CT, Lee WS. Inhibition of human vascular endothelial cells proliferation by terbinafine. Int J Cancer 2004;111:51-9.
-
(2004)
Int J Cancer
, vol.111
, pp. 51-59
-
-
Ho, P.Y.1
Liang, Y.C.2
Ho, Y.S.3
Chen, C.T.4
Lee, W.S.5
-
24
-
-
11244262363
-
Soluble Robo4 receptor inhibits in vivo angiogenesis and endothelial cell migration
-
Suchting S, Heal P, Tahtis K, Stewart LM. Bicknell R. Soluble Robo4 receptor inhibits in vivo angiogenesis and endothelial cell migration. FASEB J 2005;19:121-3.
-
(2005)
FASEB J
, vol.19
, pp. 121-123
-
-
Suchting, S.1
Heal, P.2
Tahtis, K.3
Stewart, L.M.4
Bicknell, R.5
-
25
-
-
0038034147
-
R136K fibroblast growth factor-1 mutant induces heparin-independent migration of endothelial cells through fibrin glue
-
Erzurum VZ, Bian JF, Husak VA, et al. R136K fibroblast growth factor-1 mutant induces heparin-independent migration of endothelial cells through fibrin glue. J Vasc Surg 2003;37:1075-81.
-
(2003)
J Vasc Surg
, vol.37
, pp. 1075-1081
-
-
Erzurum, V.Z.1
Bian, J.F.2
Husak, V.A.3
-
26
-
-
2442618330
-
Arginino-succinate synthase expression is required to maintain nitric oxide production and cell viability in aortic endothelial cells
-
Goodwin BL, Solomonson LP, Eichler DC. Arginino-succinate synthase expression is required to maintain nitric oxide production and cell viability in aortic endothelial cells. J Biol Chem 2004;279:18353-60.
-
(2004)
J Biol Chem
, vol.279
, pp. 18353-18360
-
-
Goodwin, B.L.1
Solomonson, L.P.2
Eichler, D.C.3
-
27
-
-
0141988698
-
Predominant role of hypoxia-inducible transcription factor (Hif)-1α versus Hif-2α in regulation of the transcriptional response to hypoxia
-
Sowter HM, Raval RR, Moore JW, Ratcliffe PJ, Harris AL. Predominant role of hypoxia-inducible transcription factor (Hif)-1α versus Hif-2α in regulation of the transcriptional response to hypoxia. Cancer Res 2003;63:6130-4.
-
(2003)
Cancer Res
, vol.63
, pp. 6130-6134
-
-
Sowter, H.M.1
Raval, R.R.2
Moore, J.W.3
Ratcliffe, P.J.4
Harris, A.L.5
-
28
-
-
0037093238
-
Expression of hypoxia-inducible factors in human renal cancer: Relationship to angiogenesis and to the von Hippel-Lindau gene mutation
-
Turner KJ, Moore JW, Jones A, et al. Expression of hypoxia-inducible factors in human renal cancer: relationship to angiogenesis and to the von Hippel-Lindau gene mutation. Cancer Res 2002;62:2957-61.
-
(2002)
Cancer Res
, vol.62
, pp. 2957-2961
-
-
Turner, K.J.1
Moore, J.W.2
Jones, A.3
-
29
-
-
0037216703
-
Regulation of Notch1 and D114 by vascular endothelial growth factor in arterial endothelial cells: Implications for modulating arteriogenesis and angiogenesis
-
Liu ZJ, Shirakawa T, Li Y, et al. Regulation of Notch1 and D114 by vascular endothelial growth factor in arterial endothelial cells: implications for modulating arteriogenesis and angiogenesis. Mol Cell Biol 2003;23:14-25.
-
(2003)
Mol Cell Biol
, vol.23
, pp. 14-25
-
-
Liu, Z.J.1
Shirakawa, T.2
Li, Y.3
-
30
-
-
0034043802
-
Contemporary approach to the classification of renal epithelial tumors
-
Reuter VE, Presti JC, Jr. Contemporary approach to the classification of renal epithelial tumors. Semin Oncol 2000;27:124-37.
-
(2000)
Semin Oncol
, vol.27
, pp. 124-137
-
-
Reuter, V.E.1
Presti Jr., J.C.2
-
31
-
-
0028072991
-
Silencing of the VHL tumor-suppressor gene by DNA methylation in renal carcinoma
-
Herman JG, Latif F, Weng Y, et al. Silencing of the VHL tumor-suppressor gene by DNA methylation in renal carcinoma. Proc Natl Acad Sci U S A 1994;91:9700-4.
-
(1994)
Proc Natl Acad Sci U S A
, vol.91
, pp. 9700-9704
-
-
Herman, J.G.1
Latif, F.2
Weng, Y.3
-
32
-
-
0027954044
-
Mutations of the VHL tumour suppressor gene in renal carcinoma
-
Gnarra JR, Tory K, Weng Y, et al. Mutations of the VHL tumour suppressor gene in renal carcinoma. Nat Genet 1994;7:85-90.
-
(1994)
Nat Genet
, vol.7
, pp. 85-90
-
-
Gnarra, J.R.1
Tory, K.2
Weng, Y.3
-
33
-
-
4744358492
-
Notch activation induces endothelial cell cycle arrest and participates in contact inhibition: Role of p21Cip1 repression
-
Noseda M, Chang L, McLean G, et al. Notch activation induces endothelial cell cycle arrest and participates in contact inhibition: role of p21Cip1 repression. Mol Cell Biol 2004;24:8813-22.
-
(2004)
Mol Cell Biol
, vol.24
, pp. 8813-8822
-
-
Noseda, M.1
Chang, L.2
McLean, G.3
-
34
-
-
0042121208
-
Angiogenic sprouting and capillary lumen formation modeled by human umbilical vein endothelial cells (HUVEC) in fibrin gels: The role of fibroblasts and Angiopoietin-1
-
Nakatsu MN, Sainson RC, Aoto JN, et al. Angiogenic sprouting and capillary lumen formation modeled by human umbilical vein endothelial cells (HUVEC) in fibrin gels: the role of fibroblasts and Angiopoietin-1. Microvasc Res 2003;66:102-12.
-
(2003)
Microvasc Res
, vol.66
, pp. 102-112
-
-
Nakatsu, M.N.1
Sainson, R.C.2
Aoto, J.N.3
-
35
-
-
0036433637
-
Notch activation during endothelial cell network formation in vitro targets the basic HLH transcription factor HESR-1 and down-regulates VEGFR-2/KDR expression
-
Taylor KL, Henderson AM, Hughes CC. Notch activation during endothelial cell network formation in vitro targets the basic HLH transcription factor HESR-1 and down-regulates VEGFR-2/KDR expression. Microvasc Res 2002;64:372-83.
-
(2002)
Microvasc Res
, vol.64
, pp. 372-383
-
-
Taylor, K.L.1
Henderson, A.M.2
Hughes, C.C.3
-
36
-
-
0036070186
-
Sonic hedgehog and vascular endothelial growth factor act upstream of the Notch pathway during arterial endothelial differentiation
-
Lawson ND, Vogel AM, Weinstein BM. sonic hedgehog and vascular endothelial growth factor act upstream of the Notch pathway during arterial endothelial differentiation. Dev Cell 2002;3:127-36.
-
(2002)
Dev Cell
, vol.3
, pp. 127-136
-
-
Lawson, N.D.1
Vogel, A.M.2
Weinstein, B.M.3
-
37
-
-
0027482301
-
Expression of basic fibroblast growth factor in primary human renal tumors: Correlation with poor survival
-
Nanus DM, Schmitz-Drager BJ, Motzer RJ, et al. Expression of basic fibroblast growth factor in primary human renal tumors: correlation with poor survival. J Natl Cancer Inst 1993;85:1597-9.
-
(1993)
J Natl Cancer Inst
, vol.85
, pp. 1597-1599
-
-
Nanus, D.M.1
Schmitz-Drager, B.J.2
Motzer, R.J.3
-
38
-
-
1642523576
-
Notch4 inhibits endothelial apoptosis via RBP-JK-dependent and -independent pathways
-
MacKenzie F, Duriez P, Wong F, Noseda M, Karsan A. Notch4 inhibits endothelial apoptosis via RBP-JK-dependent and -independent pathways. J Biol Chem 2004;279:11657-63.
-
(2004)
J Biol Chem
, vol.279
, pp. 11657-11663
-
-
MacKenzie, F.1
Duriez, P.2
Wong, F.3
Noseda, M.4
Karsan, A.5
-
40
-
-
13244255216
-
1 checkpoint controls in telomerase- immortalized endothelial cells
-
1 checkpoint controls in telomerase-immortalized endothelial cells. Cell Cycle 2004;3:811-6.
-
(2004)
Cell Cycle
, vol.3
, pp. 811-816
-
-
Freedman, D.A.1
Folkman, J.2
-
41
-
-
12144287287
-
p21Cip1 levels differentially regulate turnover of mature endothelial cells, endothelial progenitor cells, and in vivo neovascularization
-
Bruhl T, Heeschen C, Aicher A, et al. p21Cip1 levels differentially regulate turnover of mature endothelial cells, endothelial progenitor cells, and in vivo neovascularization. Circ Res 2004;94:686-92.
-
(2004)
Circ Res
, vol.94
, pp. 686-692
-
-
Bruhl, T.1
Heeschen, C.2
Aicher, A.3
-
42
-
-
0033749398
-
The antiangiogenic agent TNP-470 requires p53 and p21CIP/WAF for endothelial cell growth arrest
-
Yeh JR, Mohan R, Crews CM. The antiangiogenic agent TNP-470 requires p53 and p21CIP/WAF for endothelial cell growth arrest. Proc Natl Acad Sci USA 2000;97:12782-7.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 12782-12787
-
-
Yeh, J.R.1
Mohan, R.2
Crews, C.M.3
-
43
-
-
0034212710
-
Notch signaling is essential for vascular morphogenesis in mice
-
Krebs LT, Xue Y, Norton CR, et al. Notch signaling is essential for vascular morphogenesis in mice. Genes Dev 2000;14:1343-52.
-
(2000)
Genes Dev
, vol.14
, pp. 1343-1352
-
-
Krebs, L.T.1
Xue, Y.2
Norton, C.R.3
-
44
-
-
0035826844
-
Vascular patterning defects associated with expression of activated Notch4 in embryonic endothelium
-
Uyttendaele H, Ho J, Rossant J, Kitajewski J. Vascular patterning defects associated with expression of activated Notch4 in embryonic endothelium. Proc Natl Acad Sci U S A 2001;98:5643-8.
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, pp. 5643-5648
-
-
Uyttendaele, H.1
Ho, J.2
Rossant, J.3
Kitajewski, J.4
-
45
-
-
0035794134
-
The basic helix-loop-helix transcription factor HESR1 regulates endothelial cell tube formation
-
Henderson AM, Wang SJ, Taylor AC, Aitkenhead M, Hughes CC. The basic helix-loop-helix transcription factor HESR1 regulates endothelial cell tube formation. J Biol Chem 2001;276:6169-76.
-
(2001)
J Biol Chem
, vol.276
, pp. 6169-6176
-
-
Henderson, A.M.1
Wang, S.J.2
Taylor, A.C.3
Aitkenhead, M.4
Hughes, C.C.5
-
46
-
-
4444259419
-
Notch4-induced inhibition of endothelial sprouting requires the ankyrin repeats and involves signaling through RBP-JK
-
MacKenzie F, Duriez P, Larrivee B, et al. Notch4-induced inhibition of endothelial sprouting requires the ankyrin repeats and involves signaling through RBP-JK. Blood 2004;104:1760-8.
-
(2004)
Blood
, vol.104
, pp. 1760-1768
-
-
MacKenzie, F.1
Duriez, P.2
Larrivee, B.3
-
47
-
-
0036198525
-
Activated Notch4 inhibits angiogenesis: Role of β1-integrin activation
-
Leong KGI, Hu X, Li L, et al. Activated Notch4 inhibits angiogenesis: role of β1-integrin activation. Mol Cell Biol 2002;22:2830-41.
-
(2002)
Mol Cell Biol
, vol.22
, pp. 2830-2841
-
-
Leong, K.G.I.1
Hu, X.2
Li, L.3
|