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Volumn 2011, Issue , 2011, Pages

Oxidative stress and redox modulation potential in type 1 diabetes

Author keywords

[No Author keywords available]

Indexed keywords

ANTIOXIDANT; CATALASE; GAMMA INTERFERON; GLUTATHIONE PEROXIDASE; HYDROGEN PEROXIDE; INSULIN; INTERLEUKIN 1BETA; NITRIC OXIDE; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; SUPEROXIDE DISMUTASE; TUMOR NECROSIS FACTOR ALPHA;

EID: 79959200769     PISSN: 17402522     EISSN: 17402530     Source Type: Journal    
DOI: 10.1155/2011/593863     Document Type: Review
Times cited : (89)

References (220)
  • 1
    • 0034213186 scopus 로고    scopus 로고
    • The evolution of free radicals and oxidative stress
    • DOI 10.1016/S0002-9343(00)00412-5, PII S0002934300004125
    • McCord J. M., The evolution of free radicals and oxidative stress American Journal of Medicine 2000 108 8 652 659 (Pubitemid 30336605)
    • (2000) American Journal of Medicine , vol.108 , Issue.8 , pp. 652-659
    • McCord, J.M.1
  • 2
    • 0037421839 scopus 로고    scopus 로고
    • Chemiosmotic coupling: The cost of living
    • Rich P., Chemiosmotic coupling: the cost of living Nature 2003 421 6923 583
    • (2003) Nature , vol.421 , Issue.6923 , pp. 583
    • Rich, P.1
  • 3
    • 0015363173 scopus 로고
    • The cellular production of hydrogen peroxide
    • Boveris A., Oshino N., Chance B., The cellular production of hydrogen peroxide Biochemical Journal 1972 128 3 617 630
    • (1972) Biochemical Journal , vol.128 , Issue.3 , pp. 617-630
    • Boveris, A.1    Oshino, N.2    Chance, B.3
  • 4
    • 0030969868 scopus 로고    scopus 로고
    • Superoxide production by the mitochondrial respiratory chain
    • DOI 10.1023/A:1027374931887
    • Turrens J. F., Superoxide production by the mitochondrial respiratory chain Bioscience Reports 1997 17 1 3 8 (Pubitemid 27267586)
    • (1997) Bioscience Reports , vol.17 , Issue.1 , pp. 3-8
    • Turrens, J.F.1
  • 5
    • 0033593550 scopus 로고    scopus 로고
    • Molecular biology of aging
    • DOI 10.1016/S0092-8674(00)80567-X
    • Johnson F. B., Sinclair D. A., Guarente L., Molecular biology of aging Cell 1999 96 2 291 302 (Pubitemid 29059357)
    • (1999) Cell , vol.96 , Issue.2 , pp. 291-302
    • Johnson, F.B.1    Sinclair, D.A.2    Guarente, L.3
  • 6
    • 61649088812 scopus 로고    scopus 로고
    • The role of antioxidants and antioxidant-related enzymes in protective responses to environmentally induced oxidative stress
    • Limn-Pacheco J., Gonsebatt M. E., The role of antioxidants and antioxidant-related enzymes in protective responses to environmentally induced oxidative stress Mutation Research 2009 674 1-2 137 147
    • (2009) Mutation Research , vol.674 , Issue.12 , pp. 137-147
    • Limn-Pacheco, J.1    Gonsebatt, M.E.2
  • 9
    • 0034626735 scopus 로고    scopus 로고
    • Oxidants, oxidative stress and the biology of ageing
    • Finkel T., Holbrook N. J., Oxidants, oxidative stress and the biology of ageing Nature 2000 408 6809 239 247
    • (2000) Nature , vol.408 , Issue.6809 , pp. 239-247
    • Finkel, T.1    Holbrook, N.J.2
  • 12
    • 0029824431 scopus 로고    scopus 로고
    • Antioxidants in human health and disease
    • Halliwell B., Antioxidants in human health and disease Annual Review of Nutrition 1996 16 33 50 (Pubitemid 26286845)
    • (1996) Annual Review of Nutrition , vol.16 , pp. 33-50
    • Halliwell, B.1
  • 14
    • 0018749490 scopus 로고
    • Role of superoxide dismutase in cancer: A review
    • Oberley L. W., Buettner G. R., Role of superoxide dismutase in cancer: A review Cancer Research 1979 39 4 1141 1149 (Pubitemid 9183825)
    • (1979) Cancer Research , vol.39 , Issue.4 , pp. 1141-1149
    • Oberley, L.W.1    Buettner, G.R.2
  • 15
    • 0028900690 scopus 로고
    • Persistent oxidative stress in cancer
    • Toyokuni S., Persistent oxidative stress in cancer FEBS Letters 1995 358 1 1 3
    • (1995) FEBS Letters , vol.358 , Issue.1 , pp. 1-3
    • Toyokuni, S.1
  • 16
    • 0027198331 scopus 로고
    • Oxidative DNA damage and cellular sensitivity to oxidative stress in human autoimmune diseases
    • Bashir S., Harris G., Denman M. A., Blake D. R., Winyard P. G., Oxidative DNA damage and cellular sensitivity to oxidative stress in human autoimmune diseases Annals of the Rheumatic Diseases 1993 52 9 659 666 (Pubitemid 23280435)
    • (1993) Annals of the Rheumatic Diseases , vol.52 , Issue.9 , pp. 659-666
    • Bashir, S.1    Harris, G.2    Denman, M.A.3    Blake, D.R.4    Winyard, P.G.5
  • 17
    • 0344154565 scopus 로고    scopus 로고
    • Antioxidant status in rheumatoid arthritis and role of antioxidant therapy
    • DOI 10.1016/j.cccn.2003.08.011
    • Jaswal S., Mehta H. C., Sood A. K., Kaur J., Antioxidant status in rheumatoid arthritis and role of antioxidant therapy Clinica Chimica Acta 2003 338 1-2 123 129 (Pubitemid 37456698)
    • (2003) Clinica Chimica Acta , vol.338 , Issue.1-2 , pp. 123-129
    • Jaswal, S.1    Mehta, H.C.2    Sood, A.K.3    Kaur, J.4
  • 18
    • 0036591849 scopus 로고    scopus 로고
    • Lipid peroxidation and protein oxidation in Alzheimer's disease brain: Potential causes and consequences involving amyloid -peptide-associated free radical oxidative stress
    • DOI 10.1016/S0891-5849(02)00794-3, PII S0891584902007943
    • Butterfield D. A., Lauderback C. M., Lipid peroxidation and protein oxidation in Alzheimer's disease brain: potential causes and consequences involving amyloid -peptide-associated free radical oxidative stress Free Radical Biology and Medicine 2002 32 11 1050 1060 (Pubitemid 34603342)
    • (2002) Free Radical Biology and Medicine , vol.32 , Issue.11 , pp. 1050-1060
    • Butterfield D.Allan1    Lauderback, C.M.2
  • 19
    • 0029751104 scopus 로고    scopus 로고
    • Oxidative stress and the pathogenesis of Parkinson's disease
    • Jenner P., Olanow C. W., Oxidative stress and the pathogenesis of Parkinson's disease Neurology 1996 47 6 S161 S170
    • (1996) Neurology , vol.47 , Issue.6
    • Jenner, P.1    Olanow, C.W.2
  • 20
    • 0032731637 scopus 로고    scopus 로고
    • ALS-linked Cu/Zn-SOD mutation increases vulnerability of motor neurons to excitotoxicity by a mechanism involving increased oxidative stress and perturbed calcium homeostasis
    • Kruman I. I., Pedersen W. A., Springer J. E., Mattson M. P., ALS-linked Cu/Zn-SOD mutation increases vulnerability of motor neurons to excitotoxicity by a mechanism involving increased oxidative stress and perturbed calcium homeostasis Experimental Neurology 1999 160 1 28 39
    • (1999) Experimental Neurology , vol.160 , Issue.1 , pp. 28-39
    • Kruman, I.I.1    Pedersen, W.A.2    Springer, J.E.3    Mattson, M.P.4
  • 22
    • 33644781601 scopus 로고    scopus 로고
    • Oxidant and antioxidant balance in the airways and airway diseases
    • DOI 10.1016/j.ejphar.2005.12.087, PII S0014299905013841, The Pharmacology of the Respiratory Tract
    • Rahman I., Biswas S. K., Kode A., Oxidant and antioxidant balance in the airways and airway diseases European Journal of Pharmacology 2006 533 13 222 239 (Pubitemid 43340015)
    • (2006) European Journal of Pharmacology , vol.533 , Issue.1-3 , pp. 222-239
    • Rahman, I.1    Biswas, S.K.2    Kode, A.3
  • 24
    • 45249089262 scopus 로고    scopus 로고
    • Oxidative stress: The vulnerable -cell
    • Lenzen S., Oxidative stress: the vulnerable -cell Biochemical Society Transactions 2008 36 3 343 347
    • (2008) Biochemical Society Transactions , vol.36 , Issue.3 , pp. 343-347
    • Lenzen, S.1
  • 26
    • 75149194772 scopus 로고    scopus 로고
    • Mitochondrial dysfunction in diabetes: From molecular mechanisms to functional significance and therapeutic opportunities
    • Sivitz W. I., Yorek M. A., Mitochondrial dysfunction in diabetes: from molecular mechanisms to functional significance and therapeutic opportunities Antioxidants and Redox Signaling 2010 12 4 537 577
    • (2010) Antioxidants and Redox Signaling , vol.12 , Issue.4 , pp. 537-577
    • Sivitz, W.I.1    Yorek, M.A.2
  • 27
    • 0015596284 scopus 로고
    • Biological defense mechanisms. The production by leukocytes of superoxide, a potential bactericidal agent
    • Babior B. M., Kipnes R. S., Curnutte J. T., Biological defense mechanisms. The production by leukocytes of superoxide, a potential bactericidal agent Journal of Clinical Investigation 1973 52 3 741 744
    • (1973) Journal of Clinical Investigation , vol.52 , Issue.3 , pp. 741-744
    • Babior, B.M.1    Kipnes, R.S.2    Curnutte, J.T.3
  • 28
    • 4444221709 scopus 로고    scopus 로고
    • T cells express a phagocyte-type NADPH oxidase that is activated after T cell receptor stimulation
    • DOI 10.1038/ni1096
    • Jackson S. H., Devadas S., Kwon J., Pinto L. A., Williams M. S., T cells express a phagocyte-type NADPH oxidase that is activated after T cell receptor stimulation Nature Immunology 2004 5 8 818 827 (Pubitemid 39172975)
    • (2004) Nature Immunology , vol.5 , Issue.8 , pp. 818-827
    • Jackson, S.H.1    Devadas, S.2    Kwon, J.3    Pinto, L.A.4    Williams, M.S.5
  • 30
    • 1542406446 scopus 로고    scopus 로고
    • NOX enzymes and the biology of reactive oxygen
    • Lambeth J. D., NOX enzymes and the biology of reactive oxygen Nature Reviews Immunology 2004 4 3 181 189 (Pubitemid 38339084)
    • (2004) Nature Reviews Immunology , vol.4 , Issue.3 , pp. 181-189
    • Lambeth, J.D.1
  • 31
    • 0023277174 scopus 로고
    • Oxygen-derived radicals: A link between reperfusion injury and inflammation
    • McCord J. M., Oxygen-derived radicals: a link between reperfusion injury and inflammation Federation Proceedings 1987 46 7 2402 2406 (Pubitemid 17081554)
    • (1987) Federation Proceedings , vol.46 , Issue.7 , pp. 2402-2406
    • McCord, J.M.1
  • 34
    • 0025073266 scopus 로고
    • Modulation of fibroblast proliferation by oxygen free radicals
    • Murrell G. A. C., Francis M. J. O., Bromley L., Modulation of fibroblast proliferation by oxygen free radicals Biochemical Journal 1990 265 3 659 665 (Pubitemid 20053867)
    • (1990) Biochemical Journal , vol.265 , Issue.3 , pp. 659-665
    • Murrell, G.A.C.1    Francis, M.J.O.2    Bromley, L.3
  • 37
    • 33846233454 scopus 로고    scopus 로고
    • Disruption of innate-mediated proinflammatory cytokine and reactive oxygen species third signal leads to antigen-specific hyporesponsiveness
    • Tse H. M., Milton M. J., Schreiner S., Profozich J. L., Trucco M., Piganelli J. D., Disruption of innate-mediated proinflammatory cytokine and reactive oxygen species third signal leads to antigen-specific hyporesponsiveness Journal of Immunology 2007 178 2 908 917 (Pubitemid 46095163)
    • (2007) Journal of Immunology , vol.178 , Issue.2 , pp. 908-917
    • Tse, H.M.1    Milton, M.J.2    Schreiner, S.3    Profozich, J.L.4    Trucco, M.5    Piganelli, J.D.6
  • 39
    • 34249071326 scopus 로고    scopus 로고
    • VEGF signaling through NADPH oxidase-derived ROS
    • DOI 10.1089/ars.2007.1556
    • Ushio-Fukai M., VEGF signaling through NADPH oxidase-derived ROS Antioxidants and Redox Signaling 2007 9 6 731 739 (Pubitemid 46799105)
    • (2007) Antioxidants and Redox Signaling , vol.9 , Issue.6 , pp. 731-739
    • Ushio-Fukai, M.1
  • 40
    • 15044362438 scopus 로고    scopus 로고
    • Intracellular messenger function of hydrogen peroxide and its regulation by peroxiredoxins
    • DOI 10.1016/j.ceb.2005.02.004, Cell Regulation
    • Rhee S. G., Kang S. W., Jeong W., Chang T. S., Yang K. S., Woo H. A., Intracellular messenger function of hydrogen peroxide and its regulation by peroxiredoxins Current Opinion in Cell Biology 2005 17 2 183 189 (Pubitemid 40380942)
    • (2005) Current Opinion in Cell Biology , vol.17 , Issue.2 , pp. 183-189
    • Rhee, S.G.1    Kang, S.W.2    Jeong, W.3    Chang, T.-S.4    Yang, K.-S.5    Woo, H.A.6
  • 41
    • 33745631769 scopus 로고    scopus 로고
    • H 2 O 2, a necessary evil for cell signaling
    • Rhee S. G., H 2 O 2, a necessary evil for cell signaling Science 2006 312 5782 1882 1883
    • (2006) Science , vol.312 , Issue.5782 , pp. 1882-1883
    • Rhee, S.G.1
  • 42
    • 0029074550 scopus 로고
    • Sublethal levels of oxidant stress stimulate multiple serine/threonine kinases and suppress protein phosphatases in Jurkat T cells
    • Whisler R. L., Goyette M. A., Grants I. S., Newhouse Y. G., Sublethal levels of oxidant stress stimulate multiple serine/threonine kinases and suppress protein phosphatases in Jurkat T cells Archives of Biochemistry and Biophysics 1995 319 1 23 35
    • (1995) Archives of Biochemistry and Biophysics , vol.319 , Issue.1 , pp. 23-35
    • Whisler, R.L.1    Goyette, M.A.2    Grants, I.S.3    Newhouse, Y.G.4
  • 43
    • 4043161974 scopus 로고    scopus 로고
    • Mitochondrial redox control of matrix metalloproteinases
    • DOI 10.1016/j.freeradbiomed.2004.06.008, PII S0891584904004617
    • Nelson K. K., Melendez J. A., Mitochondrial redox control of matrix metalloproteinases Free Radical Biology and Medicine 2004 37 6 768 784 (Pubitemid 39078549)
    • (2004) Free Radical Biology and Medicine , vol.37 , Issue.6 , pp. 768-784
    • Nelson, K.K.1    Melendez, J.A.2
  • 44
    • 61449229249 scopus 로고    scopus 로고
    • Regulation of mature ADAM17 by redox agents for L-selectin shedding
    • Wang Y., Herrera A. H., Li Y., Belani K. K., Walcheck B., Regulation of mature ADAM17 by redox agents for L-selectin shedding Journal of Immunology 2009 182 4 2449 2457
    • (2009) Journal of Immunology , vol.182 , Issue.4 , pp. 2449-2457
    • Wang, Y.1    Herrera, A.H.2    Li, Y.3    Belani, K.K.4    Walcheck, B.5
  • 45
    • 53349153160 scopus 로고    scopus 로고
    • Tyrosine phosphatase SHP-1 in oxidative stress and development of allergic airway inflammation
    • You S. C., Sun Y. O., Zhu Z., Tyrosine phosphatase SHP-1 in oxidative stress and development of allergic airway inflammation American Journal of Respiratory Cell and Molecular Biology 2008 39 4 412 419
    • (2008) American Journal of Respiratory Cell and Molecular Biology , vol.39 , Issue.4 , pp. 412-419
    • You, S.C.1    Sun, Y.O.2    Zhu, Z.3
  • 47
    • 0037108204 scopus 로고    scopus 로고
    • Inhibition of PTPs by H 2 O 2 regulates the activation of distinct MAPK pathways
    • Lee K., Esselman W. J., Inhibition of PTPs by H 2 O 2 regulates the activation of distinct MAPK pathways Free Radical Biology and Medicine 2002 33 8 1121 1132
    • (2002) Free Radical Biology and Medicine , vol.33 , Issue.8 , pp. 1121-1132
    • Lee, K.1    Esselman, W.J.2
  • 48
    • 0036911138 scopus 로고    scopus 로고
    • Hydrogen peroxide as second messenger in lymphocyte activation
    • DOI 10.1038/ni1202-1129
    • Reth M., Hydrogen peroxide as second messenger in lymphocyte activation Nature Immunology 2002 3 12 1129 1134 (Pubitemid 35469696)
    • (2002) Nature Immunology , vol.3 , Issue.12 , pp. 1129-1134
    • Reth, M.1
  • 50
    • 0028342913 scopus 로고
    • Regulation of the transcription factors NF-B and AP-1 by redox changes
    • DOI 10.1016/0009-2797(94)90029-9
    • Meyer M., Pahl H. L., Baeuerle P. A., Regulation of the transcription factors NF- B and AP-1 by redox changes Chemico-Biological Interactions 1994 91 2-3 91 100 (Pubitemid 24168455)
    • (1994) Chemico-Biological Interactions , vol.91 , Issue.2-3 , pp. 91-100
    • Meyer, M.1    Pahl, H.L.2    Baeuerle, P.A.3
  • 51
    • 0025739254 scopus 로고
    • Reactive oxygen intermediates as apparently widely used messengers in the activation of the NF-B transcription factor and HIV-1
    • Schreck R., Rieber P., Baeuerle P. A., Reactive oxygen intermediates as apparently widely used messengers in the activation of the NF- B transcription factor and HIV-1 EMBO Journal 1991 10 8 2247 2258 (Pubitemid 21905698)
    • (1991) EMBO Journal , vol.10 , Issue.8 , pp. 2247-2258
    • Schreck, R.1    Rieber, P.2    Baeuerle, P.A.3
  • 52
    • 0029979744 scopus 로고    scopus 로고
    • Oxidants as stimulators of signal transduction
    • DOI 10.1016/S0891-5849(96)00275-4
    • Suzuki Y. J., Forman H. J., Sevanian A., Oxidants as stimulators of signal transduction Free Radical Biology and Medicine 1996 22 1-2 269 285 (Pubitemid 26399334)
    • (1996) Free Radical Biology and Medicine , vol.22 , Issue.1-2 , pp. 269-285
    • Suzuki, Y.J.1    Forman, H.J.2    Sevanian, A.3
  • 53
    • 1642505511 scopus 로고    scopus 로고
    • Mechanistic analysis of the immunomodulatory effects of a catalytic antioxidant on antigen-presenting cells: Implication for their use in targeting oxidation-reduction reactions in innate immunity
    • DOI 10.1016/j.freeradbiomed.2003.10.029
    • Tse H. M., Milton M. J., Piganelli J. D., Mechanistic analysis of the immunomodulatory effects of a catalytic antioxidant on antigen-presenting cells: implication for their use in targeting oxidation-reduction reactions in innate immunity Free Radical Biology and Medicine 2004 36 2 233 247 (Pubitemid 38117241)
    • (2004) Free Radical Biology and Medicine , vol.36 , Issue.2 , pp. 233-247
    • Tse, H.M.1    Milton, M.J.2    Piganelli, J.D.3
  • 54
    • 4644350365 scopus 로고    scopus 로고
    • Cutting edge: Direct interaction of TLR4 with NAD(P)H oxidase 4 isozyme is essential for lipopolysaccharide-induced production of reactive oxygen species and activation of NF-B
    • Park H. S., Jung H. Y., Park E. Y., Kim J., Lee W. J., Bae Y. S., Cutting edge: direct interaction of TLR4 with NAD(P)H oxidase 4 isozyme is essential for lipopolysaccharide-induced production of reactive oxygen species and activation of NF- B Journal of Immunology 2004 173 6 3589 3593 (Pubitemid 39280716)
    • (2004) Journal of Immunology , vol.173 , Issue.6 , pp. 3589-3593
    • Park, H.S.1    Jung, H.Y.2    Park, E.Y.3    Kim, J.4    Lee, W.J.5    Bae, Y.S.6
  • 55
    • 0141641127 scopus 로고    scopus 로고
    • Oxidative stress as an initiator of cytokine release and cell damage
    • Crapo J. D., Oxidative stress as an initiator of cytokine release and cell damage European Respiratory Journal, Supplement 2003 44 4s 6s (Pubitemid 37222052)
    • (2003) European Respiratory Journal, Supplement , vol.22 , Issue.44
    • Crapo, J.D.1
  • 58
    • 0031036917 scopus 로고    scopus 로고
    • An essential role for free radicals and derived species in signal transduction
    • Lander H. M., An essential role for free radicals and derived species in signal transduction FASEB Journal 1997 11 2 118 124 (Pubitemid 27097584)
    • (1997) FASEB Journal , vol.11 , Issue.2 , pp. 118-124
    • Lander, H.M.1
  • 59
    • 0017643480 scopus 로고
    • Hydrogen peroxide release from mouse peritoneal macrophages. Dependence on sequential activation and triggering
    • Nathan C. F., Root R. K., Hydrogen peroxide release from mouse peritoneal macrophages. Dependence on sequential activation and triggering Journal of Experimental Medicine 1977 146 6 1648 1662 (Pubitemid 8245448)
    • (1977) Journal of Experimental Medicine , vol.146 , Issue.6 , pp. 1648-1662
    • Nathan, C.F.1    Root, R.K.2
  • 60
    • 0032535491 scopus 로고    scopus 로고
    • Induction of the antigen receptor expression on B lymphocytes results in rapid competence for signaling of SLP-65 and Syk
    • DOI 10.1093/emboj/17.24.7304
    • Zhang Y., Wienands J., Zrn C., Reth M., Induction of the antigen receptor expression on B lymphocytes results in rapid competence for signaling of SLP-65 and Syk EMBO Journal 1998 17 24 7304 7310 (Pubitemid 29002699)
    • (1998) EMBO Journal , vol.17 , Issue.24 , pp. 7304-7310
    • Zhang, Y.1    Wienands, J.2    Zurn, C.3    Reth, M.4
  • 61
    • 0037033433 scopus 로고    scopus 로고
    • Discrete generation of superoxide and hydrogen peroxide by T cell receptor stimulation: Selective regulation of mitogen-activated protein kinase activation and Fas ligand expression
    • DOI 10.1084/jem.20010659
    • Devadas S., Zaritskaya L., Rhee S. G., Oberley L., Williams M. S., Discrete generation of superoxide and hydrogen peroxide by T cell receptor stimulation: selective regulation of mitogen-activated protein kinase activation and Fas ligand expression Journal of Experimental Medicine 2002 195 1 59 70 (Pubitemid 34074497)
    • (2002) Journal of Experimental Medicine , vol.195 , Issue.1 , pp. 59-70
    • Devadas, S.1    Zaritskaya, L.2    Rhee, S.G.3    Oberley, L.4    Williams, M.S.5
  • 63
    • 0031816705 scopus 로고    scopus 로고
    • The NF- B activation pathway: Its regulation and role in inflammation and cell survival
    • Karin M., The NF- B activation pathway: its regulation and role in inflammation and cell survival Cancer Journal from Scientific American 1998 4 1 S92 S99
    • (1998) Cancer Journal from Scientific American , vol.4 , Issue.1
    • Karin, M.1
  • 64
    • 33750523632 scopus 로고    scopus 로고
    • NF-B activation by reactive oxygen species: Fifteen years later
    • DOI 10.1016/j.bcp.2006.04.011, PII S0006295206002255, Cell Signalling, Transcription and Translation as Therapeutic Tergets
    • Gloire G., Legrand-Poels S., Piette J., NF- B activation by reactive oxygen species: fifteen years later Biochemical Pharmacology 2006 72 11 1493 1505 (Pubitemid 44666727)
    • (2006) Biochemical Pharmacology , vol.72 , Issue.11 , pp. 1493-1505
    • Gloire, G.1    Legrand-Poels, S.2    Piette, J.3
  • 66
    • 0026719297 scopus 로고
    • Free radicals as mediators of pancreatic islet -cell injury in autoimmune diabetes
    • Rabinovitch A., Free radicals as mediators of pancreatic islet -cell injury in autoimmune diabetes Journal of Laboratory and Clinical Medicine 1992 119 5 455 456
    • (1992) Journal of Laboratory and Clinical Medicine , vol.119 , Issue.5 , pp. 455-456
    • Rabinovitch, A.1
  • 68
    • 0033994409 scopus 로고    scopus 로고
    • Radicals and oxidative stress in diabetes
    • DOI 10.1046/j.1464-5491.2000.00259.x
    • West I. C., Radicals and oxidative stress in diabetes Diabetic Medicine 2000 17 3 171 180 (Pubitemid 30212288)
    • (2000) Diabetic Medicine , vol.17 , Issue.3 , pp. 171-180
    • West, I.C.1
  • 69
    • 23444462519 scopus 로고
    • Reactive oxygen intermediates in autoimmune islet cell destruction of the NOD mouse induced by peritoneal exudate cells (rich in macrophages) but not T cells
    • Horio E., Fukuda M., Katoh H., Petruzzelli M., Yano N., Rittershaus C., Bonner- Weir S., Hattori M., Reactive oxygen intermediates in autoimmune islet cell destruction of the NOD mouse induced by peritoneal exudate cells (rich in macrophages) but not T cells Diabetologia 1994 37 1 22 31 (Pubitemid 24044703)
    • (1994) Diabetologia , vol.37 , Issue.1 , pp. 22-31
    • Horio, F.1    Fukuda, M.2    Katoh, H.3    Petruzzelli, M.4    Yano, N.5    Rittershaus, C.6    Bonner-Weir, S.7    Hattori, M.8
  • 71
    • 0030987135 scopus 로고    scopus 로고
    • Development of autoimmune diabetes in NOD mice is associated with the formation of peroxynitrite in pancreatic islet -cells
    • Suarez-Pinzon W. L., Szab C., Rabinovitch A., Development of autoimmune diabetes in NOD mice is associated with the formation of peroxynitrite in pancreatic islet -cells Diabetes 1997 46 5 907 911 (Pubitemid 27188272)
    • (1997) Diabetes , vol.46 , Issue.5 , pp. 907-911
    • Suarez-Pinzon, W.L.1    Szabo, C.2    Rabinovitch, A.3
  • 74
    • 0030726212 scopus 로고    scopus 로고
    • Defective plasma antioxidant defenses and enhanced susceptibility to lipid peroxidation in uncomplicated IDDM
    • Santini S. A., Marra G., Giardina B., Cotroneo P., Mordente A., Martorana G. E., Manto A., Ghirlanda G., Defective plasma antioxidant defenses and enhanced susceptibility to lipid peroxidation in uncomplicated IDDM Diabetes 1997 46 11 1853 1858 (Pubitemid 27456421)
    • (1997) Diabetes , vol.46 , Issue.11 , pp. 1853-1858
    • Santini, S.A.1    Marra, G.2    Giardina, B.3    Cotroneo, P.4    Mordente, A.5    Martorana, G.E.6    Manto, A.7    Ghirlanda, G.8
  • 75
    • 0014673591 scopus 로고
    • Seasonal incidence of diabetes mellitus
    • Gamble D. R., Taylor K. W., Seasonal incidence of diabetes mellitus British medical journal 1969 3 671 631 633
    • (1969) British Medical Journal , vol.3 , Issue.671 , pp. 631-633
    • Gamble, D.R.1    Taylor, K.W.2
  • 77
    • 0015916984 scopus 로고
    • Diabetes in mice after Coxsackie B 4 virus infection
    • Coleman T. J., Gamble D. R., Taylor K. W., Diabetes in mice after Coxsackie B 4 virus infection British medical journal 1973 3 5870 25 27
    • (1973) British Medical Journal , vol.3 , Issue.5870 , pp. 25-27
    • Coleman, T.J.1    Gamble, D.R.2    Taylor, K.W.3
  • 78
    • 0018135322 scopus 로고
    • Virus-induced diabetes mellitus. XV. Beta cell damage and insulin-dependent hyperglycemia in mice infected with Coxsackie virus B4
    • Yoon J. W., Onodera T., Notkins A. L., Virus-induced diabetes mellitus. XV. Beta cell damage and insulin-dependent hyperglycemia in mice infected with Coxsackie virus B4 Journal of Experimental Medicine 1978 148 4 1068 1080 (Pubitemid 9034273)
    • (1978) Journal of Experimental Medicine , vol.148 , Issue.4 , pp. 1068-1080
    • Yoon, J.W.1    Onodera, T.2    Notkins, A.L.3
  • 79
    • 34447617193 scopus 로고    scopus 로고
    • Induction of the chemokine interferon-gamma-inducible protein-10 in human pancreatic islets during enterovirus infection
    • Berg A. K., Korsgren O., Frisk G., Induction of the chemokine interferon-gamma-inducible protein-10 in human pancreatic islets during enterovirus infection Diabetologia 2006 49 11 2697 2703
    • (2006) Diabetologia , vol.49 , Issue.11 , pp. 2697-2703
    • Berg, A.K.1    Korsgren, O.2    Frisk, G.3
  • 81
    • 0023558234 scopus 로고
    • Virus-induced formation of reactive oxygen intermediates in phagocytic cells
    • Peterhans E., Grob M., Brge T., Zanoni R., Virus-induced formation of reactive oxygen intermediates in phagocytic cells Free Radical Research Communications 1987 3 1-5 39 46
    • (1987) Free Radical Research Communications , vol.3 , Issue.15 , pp. 39-46
    • Peterhans, E.1    Grob, M.2    Brge, T.3    Zanoni, R.4
  • 82
    • 0029984682 scopus 로고    scopus 로고
    • Low antioxidant enzyme gene expression in pancreatic islets compared with various other mouse tissues
    • DOI 10.1016/0891-5849(96)02051-5
    • Lenzen S., Drinkgern J., Tiedge M., Low antioxidant enzyme gene expression in pancreatic islets compared with various other mouse tissues Free Radical Biology and Medicine 1996 20 3 463 466 (Pubitemid 26077870)
    • (1996) Free Radical Biology and Medicine , vol.20 , Issue.3 , pp. 463-466
    • Lenzen, S.1    Drinkgern, J.2    Tiedge, M.3
  • 83
    • 0030689041 scopus 로고    scopus 로고
    • Relation between antioxidant enzyme gene expression and antioxidative defense status of insulin-producing cells
    • Tiedge M., Lortz S., Drinkgern J., Lenzen S., Relation between antioxidant enzyme gene expression and antioxidative defense status of insulin-producing cells Diabetes 1997 46 11 1733 1742 (Pubitemid 27456404)
    • (1997) Diabetes , vol.46 , Issue.11 , pp. 1733-1742
    • Tiedge, M.1    Lortz, S.2    Drinkgern, J.3    Lenzen, S.4
  • 84
    • 0019852821 scopus 로고
    • CuZn-superoxide dismutase, Mn-superoxide dismutase, catalase and glutathione peroxidase in pancreatic islets and other tissues in the mouse
    • Grankvist K., Marklund S. L., Taljedal I. B., CuZn-superoxide dismutase, Mn-superoxide dismutase, catalase and glutathione peroxidase in pancreatic islets and other tissues in the mouse Biochemical Journal 1981 199 2 393 398 (Pubitemid 12216744)
    • (1981) Biochemical Journal , vol.199 , Issue.2 , pp. 393-398
    • Grankvist, K.1    Marklund, S.L.2    Taljedal, I.B.3
  • 86
    • 0033600762 scopus 로고    scopus 로고
    • Hydrogen peroxide alters mitochondrial activation and insulin secretion in pancreatic beta cells
    • Maechler P., Jornot L., Wollheim C. B., Hydrogen peroxide alters mitochondrial activation and insulin secretion in pancreatic beta cells Journal of Biological Chemistry 1999 274 39 27905 27913
    • (1999) Journal of Biological Chemistry , vol.274 , Issue.39 , pp. 27905-27913
    • Maechler, P.1    Jornot, L.2    Wollheim, C.B.3
  • 88
    • 0025271299 scopus 로고
    • In vitro restoration of insulin production in islets from adult rats treated neonatally with streptozotocin
    • Welsh N., Hellerstrom C., In vitro restoration of insulin production in islets from adult rats treated neonatally with streptozotocin Endocrinology 1990 126 4 1842 1848 (Pubitemid 20139724)
    • (1990) Endocrinology , vol.126 , Issue.4 , pp. 1842-1848
    • Welsh, N.1    Hellerstrom, C.2
  • 89
    • 0035691617 scopus 로고    scopus 로고
    • The mechanism of alloxan and streptozotocin action in B cells of the rat pancreas
    • Szkudelski T., The mechanism of alloxan and streptozotocin action in B cells of the rat pancreas Physiological Research 2001 50 6 537 546 (Pubitemid 34087272)
    • (2001) Physiological Research , vol.50 , Issue.6 , pp. 537-546
    • Szkudelski, T.1
  • 90
    • 0018192154 scopus 로고
    • Alloxan uptake by isolated rat islets of langerhans
    • Weaver D. C., McDaniel M. L., Lacy P. E., Alloxan uptake by isolated rat islets of langerhans Endocrinology 1978 102 6 1847 1855 (Pubitemid 8376446)
    • (1978) Endocrinology , vol.102 , Issue.6 , pp. 1847-1855
    • Weaver, D.C.1    McDaniel, M.L.2    Lacy, P.E.3
  • 91
    • 0023831181 scopus 로고
    • Dialuric acid autoxidation: Effects of transition metals on the reaction rate and on the generation of 'active oxygen' species
    • DOI 10.1016/0006-2952(88)90207-9
    • Munday R., Dialuric acid autoxidation: effects of transition metals on the reaction rate and on the generation of active oxygen species Biochemical Pharmacology 1988 37 3 409 413 (Pubitemid 18027349)
    • (1988) Biochemical Pharmacology , vol.37 , Issue.3 , pp. 409-413
    • Munday, R.1
  • 92
    • 0025908652 scopus 로고
    • Streptozocin- and alloxan-induced H 2 O 2 generation and DNA fragmentation in pancreatic islets: HO as mediator for DNA fragmentation
    • Takasu N., Komiya I., Asawa T., Nagasawa Y., Yamada T., Streptozocin- and alloxan-induced H 2 O 2 generation and DNA fragmentation in pancreatic islets: HO as mediator for DNA fragmentation Diabetes 1991 40 9 1141 1145
    • (1991) Diabetes , vol.40 , Issue.9 , pp. 1141-1145
    • Takasu, N.1    Komiya, I.2    Asawa, T.3    Nagasawa, Y.4    Yamada, T.5
  • 95
    • 0021092027 scopus 로고
    • Streptozotocin, but not alloxan, induces DNA repair synthesis in mouse pancreatic islets in vitro
    • Sandler S., Swenne I., Streptozotocin, but not alloxan, induces DNA repair synthesis in mouse pancreatic islets in vitro Diabetologia 1983 25 5 444 447 (Pubitemid 14235472)
    • (1983) Diabetologia , vol.25 , Issue.5 , pp. 444-447
    • Sandler, S.1    Swenne, I.2
  • 96
    • 0023820924 scopus 로고
    • - radical generation by the xanthine oxidase system of pancreatic -cells
    • DOI 10.1016/0014-5793(88)80938-4
    • Nukatsuka M., Sakurai H., Yoshimura Y., Nishida M., Kawada J., Enhancement by streptozotocin of O 2 radical generation by the xanthine oxidase system of pancreatic -cells FEBS Letters 1988 239 2 295 298 (Pubitemid 18263464)
    • (1988) FEBS Letters , vol.239 , Issue.2 , pp. 295-298
    • Nukatsuka, M.1    Sakurai, H.2    Yoshimura, Y.3    Nishida, M.4    Kawada, J.5
  • 97
    • 0029257151 scopus 로고
    • Nitric oxide generation during cellular metabolization of the diabetogenic N-methyl-N-nitroso-urea streptozotozin contributes to islet cell DNA damage
    • Kroncke K. D., Fehsel K., Sommer A., Rodriguez M. L., Kolb-Bachofen V., Nitric oxide generation during cellular metabolization of the diabetogenic N-methyl-N-nitroso-urea streptozotozin contributes to islet cell DNA damage Biological Chemistry Hoppe-Seyler 1995 376 3 179 185
    • (1995) Biological Chemistry Hoppe-Seyler , vol.376 , Issue.3 , pp. 179-185
    • Kroncke, K.D.1    Fehsel, K.2    Sommer, A.3    Rodriguez, M.L.4    Kolb-Bachofen, V.5
  • 98
    • 34250340017 scopus 로고    scopus 로고
    • Glucose, palmitate and pro-inflammatory cytokines modulate production and activity of a phagocyte-like NADPH oxidase in rat pancreatic islets and a clonal beta cell line
    • Morgan D., Oliveira-Emilio H. R., Keane D., Hirata A. E., Santos da Rocha M., Bordin S., Curi R., Newsholme P., Carpinelli A. R., Glucose, palmitate and pro-inflammatory cytokines modulate production and activity of a phagocyte-like NADPH oxidase in rat pancreatic islets and a clonal beta cell line Diabetologia 2007 50 2 359 369
    • (2007) Diabetologia , vol.50 , Issue.2 , pp. 359-369
    • Morgan, D.1    Oliveira-Emilio, H.R.2    Keane, D.3    Hirata, A.E.4    Santos Da Rocha, M.5    Bordin, S.6    Curi, R.7    Newsholme, P.8    Carpinelli, A.R.9
  • 100
    • 33750808412 scopus 로고    scopus 로고
    • Chronic hyperglycemia predisposes to exaggerated inflammatory response and leukocyte dysfunction in Akita mice
    • Gyurko R., Siqueira C. C., Caldon N., Gao LI., Kantarci A., Van Dyke T. E., Chronic hyperglycemia predisposes to exaggerated inflammatory response and leukocyte dysfunction in Akita mice Journal of Immunology 2006 177 10 7250 7256 (Pubitemid 44715094)
    • (2006) Journal of Immunology , vol.177 , Issue.10 , pp. 7250-7256
    • Gyurko, R.1    Siqueira, C.C.2    Caldon, N.3    Gao, L.4    Kantarci, A.5    Van Dyke, T.E.6
  • 102
    • 0024211490 scopus 로고
    • Evidence for initial involvement of macrophage in development of insulitis in NOD mice
    • Lee K., Amano K., Yoon J., Evidence for initial involvement of macrophage in development of insulitis in NOD mice Diabetes 1988 37 7 989 991 (Pubitemid 19043733)
    • (1988) Diabetes , vol.37 , Issue.7 , pp. 989-991
    • Lee, K.1    Amano, K.2    Yoon, J.3
  • 107
    • 0025817159 scopus 로고
    • Cytokine gene expression in the islets of the diabetic Biobreeding/Worcester rat
    • Jiang Z., Woda B. A., Cytokine gene expression in the islets of the diabetic Biobreeding/Worcester rat Journal of Immunology 1991 146 9 2990 2994
    • (1991) Journal of Immunology , vol.146 , Issue.9 , pp. 2990-2994
    • Jiang, Z.1    Woda, B.A.2
  • 110
    • 0025685395 scopus 로고
    • Inhibition of insulin secretion by interleukin-1 and tumour necrosis factor- via an L-arginine-dependent nitric oxide generating mechanism
    • Southern C., Schulster D., Green I. C., Inhibition of insulin secretion by interleukin-1 and tumour necrosis factor- via an L-arginine-dependent nitric oxide generating mechanism FEBS Letters 1990 276 1-2 42 44
    • (1990) FEBS Letters , vol.276 , Issue.12 , pp. 42-44
    • Southern, C.1    Schulster, D.2    Green, I.C.3
  • 112
    • 0023601773 scopus 로고
    • Human tumor necrosis factor potentiates human interleukin 1-mediated rat pancreatic -cell cytotoxicity
    • Mandrup-Poulsen T., Bendtzen K., Dinarello C. A., Nerup J., Human tumor necrosis factor potentiates human interleukin 1-mediated rat pancreatic -cell cytotoxicity Journal of Immunology 1987 139 12 4077 4082 (Pubitemid 18013701)
    • (1987) Journal of Immunology , vol.139 , Issue.12 , pp. 4077-4082
    • Mandrup-Poulsen, T.1    Bendtzen, K.2    Dinarello, C.A.3    Nerup, J.4
  • 113
    • 0023856452 scopus 로고
    • Regulation of MHC protein expression in pancreatic -cells by interferon- and tumor necrosis factor
    • Campbell I. L., Oxbrow L., West J., Harrison L. C., Regulation of MHC protein expression in pancreatic beta-cells by interferon-gamma and tumor necrosis factor-alpha Molecular Endocrinology 1988 2 101 107 (Pubitemid 18080058)
    • (1988) Molecular Endocrinology , vol.2 , Issue.2 , pp. 101-107
    • Campbell, I.L.1    Oxbrow, L.2    West, J.3    Harrison, L.C.4
  • 114
    • 0033858841 scopus 로고    scopus 로고
    • Beta cell destruction in the development of autoimmune diabetes in the non-obese diabetic (NOD) mouse
    • DOI 10.1002/1520-7560(200007/08) 16:4<251::AID-DMRR126>3.0.CO;2-C
    • Thomas H. E., Kay T. W. H., Beta cell destruction in the development of autoimmune diabetes in the non-obese diabetic (NOD) mouse Diabetes/Metabolism Research and Reviews 2000 16 4 251 261 (Pubitemid 30611785)
    • (2000) Diabetes/Metabolism Research and Reviews , vol.16 , Issue.4 , pp. 251-261
    • Thomas, H.E.1    Kay, T.W.H.2
  • 115
    • 0142043984 scopus 로고    scopus 로고
    • Redox signaling and the MAP kinase pathways
    • Torres M., Forman H. J., Redox signaling and the MAP kinase pathways BioFactors 2003 17 1-4 287 296 (Pubitemid 37267162)
    • (2003) BioFactors , vol.17 , Issue.1-4 , pp. 287-296
    • Torres, M.1    Forman, H.J.2
  • 116
    • 0036165578 scopus 로고    scopus 로고
    • h2 balance is dependent on the intracellular thiol redox status of macrophages due to the distinctive cytokine production
    • Murata Y., Shimamura T., Hamuro J., The polarization of Th1/Th2 balance is dependent on the intracellular thiol redox status of macrophages due to the distinctive cytokine production International Immunology 2002 14 2 201 212 (Pubitemid 34144744)
    • (2002) International Immunology , vol.14 , Issue.2 , pp. 201-212
    • Murata, Y.1    Shimamura, T.2    Hamuro, J.3
  • 117
    • 0022459815 scopus 로고
    • Multiple biological activities of human recombinant interleukin 1
    • Dinarello C. A., Cannon J. G., Mier J. W., Multiple biological activities of human recombinant interleukin 1 Journal of Clinical Investigation 1986 77 6 1734 1739 (Pubitemid 16062623)
    • (1986) Journal of Clinical Investigation , vol.77 , Issue.6 , pp. 1734-1739
    • Dinarello, C.A.1    Cannon, J.G.2    Mier, J.W.3
  • 118
    • 0032214715 scopus 로고    scopus 로고
    • Local expression of TNF in neonatal NOD mice promotes diabetes by enhancing presentation of islet antigens
    • Green E. A., Eynon E. E., Flaveirti R. A., Local expression of TNF in neonatal NOD mice promotes diabetes by enhancing presentation of islet antigens Immunity 1998 9 5 733 743 (Pubitemid 28557601)
    • (1998) Immunity , vol.9 , Issue.5 , pp. 733-743
    • Green, E.A.1    Eynon, E.E.2    Flaveirti, R.A.3
  • 119
    • 0035890815 scopus 로고    scopus 로고
    • Hydrogen peroxide mediates activation of nuclear factor of activated T cells (NFAT) by nickel subsulfide
    • Huang C., Li J., Costa M., Zhang Z., Leonard S. S., Castranova V., Vallyathan V., Ju G., Shi X., Hydrogen peroxide mediates activation of nuclear factor of activated T cells (NFAT) by nickel subsulfide Cancer Research 2001 61 22 8051 8057 (Pubitemid 33091588)
    • (2001) Cancer Research , vol.61 , Issue.22 , pp. 8051-8057
    • Huang, C.1    Li, J.2    Costa, M.3    Zhang, Z.4    Leonard, S.S.5    Castranova, V.6    Vallyathan, V.7    Ju, G.8    Shi, X.9
  • 121
    • 0344667552 scopus 로고    scopus 로고
    • NF-B activation pathways induced by T cell costimulation
    • DOI 10.1096/fj.02-1100rev
    • Schmitz M. L., Bacher S., Dienz O., NF- B activation pathways induced by T cell costimulation FASEB Journal 2003 17 15 2187 2193 (Pubitemid 37509574)
    • (2003) FASEB Journal , vol.17 , Issue.15 , pp. 2187-2193
    • Schmitz, M.L.1    Bacher, S.2    Dienz, O.3
  • 122
    • 0031183099 scopus 로고    scopus 로고
    • Role of Macrophages and Macrophage-Derived Cytokines in the Pathogenesis of Kilham Rat Virus-Induced Autoimmune Diabetes in Diabetes-Resistant BioBreeding Rats
    • Chung Y.-H., Jun H.-S., Kang Y., Hirasawa K., Lee B.-R., Van Rooijen N., Yoon J.-W., Role of macrophages and macrophage-derived cytokines in the pathogenesis of Kilham rat virus-induced autoimmune diabetes in diabetes-resistant BioBreeding rats Journal of Immunology 1997 159 1 466 471 (Pubitemid 127493733)
    • (1997) Journal of Immunology , vol.159 , Issue.1 , pp. 466-471
    • Chung, Y.-H.1    Jun, H.-S.2    Kang, Y.3    Hirasawa, K.4    Lee, B.-R.5    Van Rooijen, N.6    Yoon, J.-W.7
  • 123
    • 0345422708 scopus 로고    scopus 로고
    • Disruption of the STAT4 signaling pathway protects from autoimmune diabetes while retaining antiviral immune competence
    • Holz A., Adrian B., Coon B., Wolfe T., Grusby M. J., Von Herrath M. G., Disruption of the STAT4 signaling pathway protects from autoimmune diabetes while retaining antiviral immune competence Journal of Immunology 1999 163 10 5374 5382
    • (1999) Journal of Immunology , vol.163 , Issue.10 , pp. 5374-5382
    • Holz, A.1    Adrian, B.2    Coon, B.3    Wolfe, T.4    Grusby, M.J.5    Von Herrath, M.G.6
  • 124
    • 0028943484 scopus 로고
    • Interleukin 12 signaling in T helper type 1 (Th1) cells involves tyrosine phosphorylation of signal transducer and activator of transcription (Stat)3 and Stat4
    • Jacobson N. G., Szabo S. J., Weber-Nordt R. M., Zhong Z., Schreiber R. D., Darnell J. E., Murphy K. M., Interleukin 12 signaling in T helper type 1 (Th1) cells involves tyrosine phosphorylation of signal transducer and activator of transcription (Stat)3 and Stat4 Journal of Experimental Medicine 1995 181 5 1755 1762
    • (1995) Journal of Experimental Medicine , vol.181 , Issue.5 , pp. 1755-1762
    • Jacobson, N.G.1    Szabo, S.J.2    Weber-Nordt, R.M.3    Zhong, Z.4    Schreiber, R.D.5    Darnell, J.E.6    Murphy, K.M.7
  • 125
    • 0027422313 scopus 로고
    • + t cells from TCR transgenic mice: IL-12 substitution for macrophages to stimulate IFN- production is IFN-dependent
    • Macatonia S. E., Hsieh C.-S., Murphy K. M., O'Garra A., Dendritic cells and macrophages are required for Th1 development of CD4+ t cells from TCR transgenic mice: IL-12 substitution for macrophages to stimulate IFN- production is IFN- -dependent International Immunology 1993 5 9 1119 1128 (Pubitemid 23291161)
    • (1993) International Immunology , vol.5 , Issue.9 , pp. 1119-1128
    • Macatonia, S.E.1    Hsieh, C.-S.2    Murphy, K.M.3    O'Garra, A.4
  • 129
    • 33644749322 scopus 로고    scopus 로고
    • Mechanisms of pancreatic -cell death in type 1 and type 2 diabetes: Many differences, few similarities
    • supplement 2
    • Cnop M., Welsh N., Jonas J.-C., Jrns A., Lenzen S., Eizirik D. L., Mechanisms of pancreatic -cell death in type 1 and type 2 diabetes: many differences, few similarities Diabetes 2005 54 supplement 2 S97 S107
    • (2005) Diabetes , vol.54
    • Cnop, M.1    Welsh, N.2    Jonas, J.-C.3    Jrns, A.4    Lenzen, S.5    Eizirik, D.L.6
  • 130
    • 45249091262 scopus 로고    scopus 로고
    • Use of a systems biology approach to understand pancreatic -cell death in Type 1 diabetes
    • DOI 10.1042/BST0360321
    • Eizirik D. L., Moore F., Flamez D., Ortis F., Use of a systems biology approach to understand pancreatic -cell death in Type 1 diabetes Biochemical Society Transactions 2008 36 3 321 327 (Pubitemid 351839324)
    • (2008) Biochemical Society Transactions , vol.36 , Issue.3 , pp. 321-327
    • Eizirik, D.L.1    Moore, F.2    Flamez, D.3    Ortis, F.4
  • 132
    • 0033305236 scopus 로고    scopus 로고
    • Tumor necrosis factor-activated cell death pathways in NIT-1 insulinoma cells and primary pancreatic cells
    • Stephens L. A., Thomas H. E., Ming L., Darwiche M. G.R., Volodin L., Kay T. W.H., Tumor necrosis factor- -activated cell death pathways in NIT-1 insulinoma cells and primary pancreatic cells Endocrinology 1999 140 7 3219 3227 (Pubitemid 30650640)
    • (1999) Endocrinology , vol.140 , Issue.7 , pp. 3219-3227
    • Stephens, L.A.1    Thomas, H.E.2    Ming, L.3    Darwiche, M.G.R.4    Volodin, L.5    Kay, T.W.H.6
  • 133
    • 24344453811 scopus 로고    scopus 로고
    • Synergistic activation of JNK/SAPK induced by TNF- and IFN-: Apoptosis of pancreatic -cells via the p53 and ROS pathway
    • DOI 10.1016/j.cellsig.2005.03.020, PII S0898656805000586
    • Kim W. H., Lee J. W., Gao B., Jung M. H., Synergistic activation of JNK/SAPK induced by TNF- and IFN- : apoptosis of pancreatic -cells via the p53 and ROS pathway Cellular Signalling 2005 17 12 1516 1532 (Pubitemid 41253991)
    • (2005) Cellular Signalling , vol.17 , Issue.12 , pp. 1516-1532
    • Kim, W.H.1    Lee, J.W.2    Gao, B.3    Jung, M.H.4
  • 134
    • 0035668779 scopus 로고    scopus 로고
    • A choice of death - The signal-transduction of immune-mediated beta-cell apoptosis
    • DOI 10.1007/s001250100021
    • Eizirik D. L., Mandrup-Poulsen T., A choice of deaththe signal-transduction of immune-mediated beta-cell apoptosis Diabetologia 2001 44 12 2115 2133 (Pubitemid 34015464)
    • (2001) Diabetologia , vol.44 , Issue.12 , pp. 2115-2133
    • Eizirik, D.L.1    Mandrup-Poulsen, T.2
  • 136
    • 0032768476 scopus 로고    scopus 로고
    • + T cells autoimmune diabetes through the use of TCR transgenic mice
    • DOI 10.1111/j.1600-065X.1999.tb01306.x
    • Suri A., Katz J. D., Dissecting the role of CD4+ T cells autoimmune diabetes through the use of TCR transgenic mice Immunological Reviews 1999 169 55 65 (Pubitemid 29338723)
    • (1999) Immunological Reviews , vol.169 , pp. 55-65
    • Suri, A.1    Katz, J.D.2
  • 138
    • 0023544492 scopus 로고
    • + cells
    • Bendelac A., Carnaud C., Boitard C., Bach J. F., Syngeneic transfer of autoimmune diabetes from diabetic NOD mice to healthy neonates. Requirement for both L3T4+ and Lyt-2+ cells Journal of Experimental Medicine 1987 166 4 823 832 (Pubitemid 18024228)
    • (1987) Journal of Experimental Medicine , vol.166 , Issue.4 , pp. 823-832
    • Bendelac, A.1    Carnaud, C.2    Boitard, C.3    Bach, J.F.4
  • 139
    • 0027468997 scopus 로고
    • a donors
    • Christianson S. W., Shultz L. D., Leiter E. H., Adoptive transfer of diabetes into immunodeficient NOD-scid/scid mice: relative contributions of CD4+ and CD8+ T-cells from diabetic versus prediabetic NOD.NON-Thy-1 donors Diabetes 1993 42 1 44 55 (Pubitemid 23013794)
    • (1993) Diabetes , vol.42 , Issue.1 , pp. 44-55
    • Christianson, S.W.1    Shultz, L.D.2    Leiter, E.H.3
  • 140
    • 0033526068 scopus 로고    scopus 로고
    • In autoimmune diabetes the transition from benign to pernicious insulitis requires an islet cell response to tumor necrosis factor
    • DOI 10.1084/jem.189.7.1053
    • Pakala S. V., Chivetta M., Kelly C. B., Katz J. D., In autoimmune diabetes the transition from benign to pernicious insulitis requires an islet cell response to tumor necrosis factor Journal of Experimental Medicine 1999 189 7 1053 1062 (Pubitemid 29169822)
    • (1999) Journal of Experimental Medicine , vol.189 , Issue.7 , pp. 1053-1062
    • Pakala, S.V.1    Chivetta, M.2    Kelly, C.B.3    Katz, J.D.4
  • 142
    • 1842289172 scopus 로고    scopus 로고
    • Reduced incidence and delayed onset of diabetes in perforin-deficient nonobese diabetic mice
    • DOI 10.1084/jem.186.7.989
    • Kgi D., Odermatt B., Seiler P., Zinkernagel R. M., Mak T. W., Hengartner H., Reduced incidence and delayed onset of diabetes in perforin-deficient nonobese diabetic mice Journal of Experimental Medicine 1997 186 7 989 997 (Pubitemid 27441144)
    • (1997) Journal of Experimental Medicine , vol.186 , Issue.7 , pp. 989-997
    • Kagi, D.1    Odermatt, B.2    Seiler, P.3    Zinkernagel, R.M.4    Mak, T.W.5    Hengartner, H.6
  • 144
    • 0029817047 scopus 로고    scopus 로고
    • The role of interleukin-1 in the pathogenesis of IDDM
    • DOI 10.1007/s001250050548
    • Mandrup-Poulsen T., The role of interleukin-1 in the pathogenesis of IDDM Diabetologia 1996 39 9 1005 1029 (Pubitemid 26275930)
    • (1996) Diabetologia , vol.39 , Issue.9 , pp. 1005-1029
    • Mandrup-Poulsen, T.1
  • 145
    • 78650853311 scopus 로고    scopus 로고
    • Two tales of antioxidant enzymes on beta cells and diabetes
    • In press
    • Lei X. G., Vatamaniuk M. Z., Two tales of antioxidant enzymes on beta cells and diabetes. Antioxid Redox Signal. In press
    • Antioxid Redox Signal
    • Lei, X.G.1    Vatamaniuk, M.Z.2
  • 146
    • 0742271154 scopus 로고    scopus 로고
    • Enhanced expression of glutathione peroxidase protects islet cells from hypoxia-reoxygenation
    • DOI 10.1111/j.1399-3089.2004.00082.x
    • Lepore D. A., Shinkel T. A., Fisicaro N., Mysore T. B., Johnson L. E. A., D'Apice A. J. F., Cowan P. J., Enhanced expression of glutathione peroxidase protects islet cells from hypoxia-reoxygenation Xenotransplantation 2004 11 1 53 59 (Pubitemid 38160266)
    • (2004) Xenotransplantation , vol.11 , Issue.1 , pp. 53-59
    • Lepore, D.A.1    Shinkel, T.A.2    Fisicaro, N.3    Mysore, T.B.4    Johnson, L.E.A.5    D'Apice, A.J.F.6    Cowan, P.J.7
  • 147
    • 0037957300 scopus 로고    scopus 로고
    • Protection of insulin-secreting INS-1 cells against oxidative stress through adenoviral-mediated glutathione peroxidase overexpression
    • Moriscot C., Richard M. J., Favrot M. C., Benhamou P. Y., Protection of insulin-secreting INS-1 cells against oxidative stress through adenoviral-mediated glutathione peroxidase overexpression Diabetes and Metabolism 2003 29 145 151 (Pubitemid 36576093)
    • (2003) Diabetes and Metabolism , vol.29 , Issue.2 , pp. 145-151
    • Moriscot, C.1    Richard, M.J.2    Favrot, M.C.3    Benhamou, P.Y.4
  • 148
    • 0035146709 scopus 로고    scopus 로고
    • Protective effects of a new stable, highly active SOD mimetic, M40401 in splanchnic artery occlusion and reperfusion
    • Cuzzocrea S., Mazzon E., Dugo L., Caputi A. P., Aston K., Riley D. P., Salvemini D., Protective effects of a new stable, highly active SOD mimetic, M40401 in splanchnic artery occlusion and reperfusion British Journal of Pharmacology 2001 132 1 19 29 (Pubitemid 32128430)
    • (2001) British Journal of Pharmacology , vol.132 , Issue.1 , pp. 19-29
    • Cuzzocrea, S.1    Mazzon, E.2    Dugo, L.3    Caputi, A.P.4    Aston, K.5    Riley, D.P.6    Salvemini, D.7
  • 150
    • 0033921459 scopus 로고    scopus 로고
    • Protection of insulin-producing RINm5F cells against cytokine-mediated toxicity through overexpression of antioxidant enzymes
    • Lortz S., Tiedge M., Nachtwey T., Karlsen A. E., Nerup J., Lenzen S., Protection of insulin-producing RINm5F cells against cytokine-mediated toxicity through overexpression of antioxidant enzymes Diabetes 2000 49 7 1123 1130 (Pubitemid 30439085)
    • (2000) Diabetes , vol.49 , Issue.7 , pp. 1123-1130
    • Lortz, S.1    Tiedge, M.2    Nachtwey, T.3    Karlsen, A.E.4    Nerup, J.5    Lenzen, S.6
  • 151
    • 0030927342 scopus 로고    scopus 로고
    • The cell transcription factors and development of the pancreas
    • DOI 10.1007/s001090050118
    • Sander M., German M. S., The cell transcription factors and development of the pancreas Journal of Molecular Medicine 1997 75 5 327 340 (Pubitemid 27247964)
    • (1997) Journal of Molecular Medicine , vol.75 , Issue.5 , pp. 327-340
    • Sander, M.1    German, M.S.2
  • 154
    • 33646549635 scopus 로고    scopus 로고
    • Phosphorylation marks IPF1/PDX1 protein for degradation by glycogen synthase kinase 3-dependent mechanisms
    • DOI 10.1074/jbc.M511597200
    • Boucher M. J., Selander L., Carlsson L., Edlund H., Phosphorylation marks IPF1/PDX1 protein for degradation by glycogen synthase kinase 3-dependent mechanisms Journal of Biological Chemistry 2006 281 10 6395 6403 (Pubitemid 43847571)
    • (2006) Journal of Biological Chemistry , vol.281 , Issue.10 , pp. 6395-6403
    • Boucher, M.-J.1    Selander, L.2    Carlsson, L.3    Edlund, H.4
  • 155
    • 48149100761 scopus 로고    scopus 로고
    • Molecular mechanisms for hyperinsulinaemia induced by overproduction of selenium-dependent glutathione peroxidase-1 in mice
    • Wang X. D., Vatamaniuk M. Z., Wang S. K., Roneker C. A., Simmons R. A., Lei X. G., Molecular mechanisms for hyperinsulinaemia induced by overproduction of selenium-dependent glutathione peroxidase-1 in mice Diabetologia 2008 51 8 1515 1524
    • (2008) Diabetologia , vol.51 , Issue.8 , pp. 1515-1524
    • Wang, X.D.1    Vatamaniuk, M.Z.2    Wang, S.K.3    Roneker, C.A.4    Simmons, R.A.5    Lei, X.G.6
  • 156
    • 33748329472 scopus 로고    scopus 로고
    • Metallothionein and catalase sensitize to diabetes in nonobese diabetic mice: Reactive oxygen species may have a protective role in pancreatic -cells
    • DOI 10.2337/db05-1357
    • Li X., Chen H., Epstein P. N., Metallothionein and catalase sensitize to diabetes in nonobese diabetic mice: reactive oxygen species may have a protective role in pancreatic -cells Diabetes 2006 55 6 1592 1604 (Pubitemid 44324111)
    • (2006) Diabetes , vol.55 , Issue.6 , pp. 1592-1604
    • Li, X.1    Chen, H.2    Epstein, P.N.3
  • 158
    • 0036628729 scopus 로고    scopus 로고
    • Overexpression of extracellular-SOD in islets of nonobese diabetic mice and development of diabetes
    • DOI 10.1016/S0891-5849(02)00859-6, PII S0891584902008596
    • Sandstrm J., Jonsson L. M., Edlund H., Holmberg D., Marklund S. L., Overexpression of extracellular-SOD in islets of nonobese diabetic mice and development of diabetes Free Radical Biology and Medicine 2002 33 1 71 75 (Pubitemid 34681008)
    • (2002) Free Radical Biology and Medicine , vol.33 , Issue.1 , pp. 71-75
    • Sandstrom, J.1    Jonsson, L.M.2    Edlund, H.3    Holmberg, D.4    Marklund, S.L.5
  • 159
    • 12744279326 scopus 로고    scopus 로고
    • Redox paradox: Insulin action is facilitated by insulin-stimulated reactive oxygen species with multiple potential signaling targets
    • Goldstein B. J., Kalyankar M., Wu X., Redox paradox: insulin action is facilitated by insulin-stimulated reactive oxygen species with multiple potential signaling targets Diabetes 2005 54 2 311 321
    • (2005) Diabetes , vol.54 , Issue.2 , pp. 311-321
    • Goldstein, B.J.1    Kalyankar, M.2    Wu, X.3
  • 160
    • 0032547768 scopus 로고    scopus 로고
    • Pancreatic cell-specific expression of thioredoxin, an antioxidative and antiapoptotic protein, prevents autoimmune and streptozotocin-induced diabetes
    • DOI 10.1084/jem.188.8.1445
    • Hotta M., Tashiro F., Ikegami H., Niwa H., Ogihara T., Yodoi J., Miyazaki J. I., Pancreatic cell-specific expression of thioredoxin, an antioxidative and antiapoptotic protein, prevents autoimmune and streptozotocin-induced diabetes Journal of Experimental Medicine 1998 188 8 1445 1451 (Pubitemid 28489581)
    • (1998) Journal of Experimental Medicine , vol.188 , Issue.8 , pp. 1445-1451
    • Hotta, M.1    Tashiro, F.2    Ikegami, H.3    Niwa, H.4    Ogihara, T.5    Yodoi, J.6    Miyazaki, J.-I.7
  • 161
    • 0032847555 scopus 로고    scopus 로고
    • Overexpression of catalase provides partial protection to transgenic mouse beta cells
    • DOI 10.1016/S0891-5849(99)00130-6, PII S0891584999001306
    • Xu B. O., Moritz J. T., Epstein P. N., Overexpression of catalase provides partial protection to transgenic mouse beta cells Free Radical Biology and Medicine 1999 27 7-8 830 837 (Pubitemid 29454586)
    • (1999) Free Radical Biology and Medicine , vol.27 , Issue.7-8 , pp. 830-837
    • Xu, B.1    Moritz, J.T.2    Epstein, P.N.3
  • 163
    • 0035461380 scopus 로고    scopus 로고
    • Overexpression of Metallothionein in Pancreatic -Cells Reduces Streptozotocin-Induced DNA Damage and Diabetes
    • Chen H., Carlson E. C., Pellet L., Moritz J. T., Epstein P. N., Overexpression of metallothionein in pancreatic -cells reduces streptozotocin-induced DNA damage and diabetes Diabetes 2001 50 9 2040 2046 (Pubitemid 33643670)
    • (2001) Diabetes , vol.50 , Issue.9 , pp. 2040-2046
    • Chen, H.1    Carlson, E.C.2    Pellet, L.3    Moritz, J.T.4    Epstein, P.N.5
  • 164
    • 77957653459 scopus 로고    scopus 로고
    • Transgenic expression of haem oxygenase-1 in pancreatic beta cells protects non-obese mice used as a model of diabetes from autoimmune destruction and prolongs graft survival following islet transplantation
    • Huang S. H., Chu C. H., Yu J. C., Chuang W. C., Lin G. J., Chen P. L., Chou F. C., Chau L. Y., Sytwu H. K., Transgenic expression of haem oxygenase-1 in pancreatic beta cells protects non-obese mice used as a model of diabetes from autoimmune destruction and prolongs graft survival following islet transplantation Diabetologia 2010 53 11 2389 2400
    • (2010) Diabetologia , vol.53 , Issue.11 , pp. 2389-2400
    • Huang, S.H.1    Chu, C.H.2    Yu, J.C.3    Chuang, W.C.4    Lin, G.J.5    Chen, P.L.6    Chou, F.C.7    Chau, L.Y.8    Sytwu, H.K.9
  • 165
    • 0030798658 scopus 로고    scopus 로고
    • Targeted overexpression of Cu/Zn superoxide dismutase protects pancreatic -cells against oxidative stress
    • Kubisch H. M., Wang J., Bray T. M., Phillips J. P., Targeted overexpression of Cu/Zn superoxide dismutase protects pancreatic -cells against oxidative stress Diabetes 1997 46 10 1563 1566 (Pubitemid 27411230)
    • (1997) Diabetes , vol.46 , Issue.10 , pp. 1563-1566
    • Kubisch, H.-M.1    Wang, J.2    Bray, T.M.3    Phillips, J.P.4
  • 166
    • 0032867196 scopus 로고    scopus 로고
    • Constitutive differences in antioxidant defense status distinguish alloxan-resistant and alloxan-susceptible mice
    • DOI 10.1016/S0891-5849(99)00084-2, PII S0891584999000842
    • Mathews C. E., Leiter E. H., Constitutive differences in antioxidant defense status distinguish alloxan-resistant and alloxan-susceptible mice Free Radical Biology and Medicine 1999 27 3-4 449 455 (Pubitemid 29395440)
    • (1999) Free Radical Biology and Medicine , vol.27 , Issue.3-4 , pp. 449-455
    • Mathews, C.E.1    Leiter, E.H.2
  • 167
    • 0027413011 scopus 로고
    • Lazaroid antioxidant reduces incidence of diabetes and insulitis in nonobese diabetic mice
    • Rabinovitch A., Suarez W. L., Power R. F., Lazaroid antioxidant reduces incidence of diabetes and insulitis in nonobese diabetic mice Journal of Laboratory and Clinical Medicine 1993 121 4 603 607 (Pubitemid 23112655)
    • (1993) Journal of Laboratory and Clinical Medicine , vol.121 , Issue.4 , pp. 603-607
    • Rabinovitch, A.1    Suarez, W.L.2    Power, R.F.3
  • 168
    • 0033842759 scopus 로고    scopus 로고
    • Zinc sulphate induces metallothionein in pancreatic islets of mice and protects against diabetes induced by multiple low doses of streptozotocin
    • Ohly P., Dohle C., Abel J., Seissler J., Gleichmann H., Zinc sulphate induces metallothionein in pancreatic islets of mice and protects against diabetes induced by multiple low doses of streptozotocin Diabetologia 2000 43 8 1020 1030 (Pubitemid 30655722)
    • (2000) Diabetologia , vol.43 , Issue.8 , pp. 1020-1030
    • Ohly, P.1    Dohle, C.2    Abel, J.3    Seissler, J.4    Gleichmann, H.5
  • 169
    • 2142681896 scopus 로고    scopus 로고
    • Immunosuppressive and anti-inflammatory action of antioxidants in rat autoimmune diabetes
    • DOI 10.1016/j.jaut.2004.01.005, PII S089684110400006X
    • Stosic-Grujicic S. D., Miljkovic D. M., Cvetkovic I. D., Maksimovic-Ivanic D. D., Trajkovic V., Immunosuppressive and anti-inflammatory action of antioxidants in rat autoimmune diabetes Journal of Autoimmunity 2004 22 4 267 276 (Pubitemid 38548857)
    • (2004) Journal of Autoimmunity , vol.22 , Issue.4 , pp. 267-276
    • Stosic-Grujicic, S.D.1    Miljkovic, D.M.2    Cvetkovic, I.D.3    Maksimovic-Ivanic, D.D.4    Trajkovic, V.5
  • 170
    • 34248182498 scopus 로고    scopus 로고
    • Systemic expression of heme oxygenase-1 ameliorates type 1 diabetes in NOD mice
    • Hu C. M., Lin H. H., Chiang M. T., Chang PI. F., Chau L. Y., Systemic expression of heme oxygenase-1 ameliorates type 1 diabetes in NOD mice Diabetes 2007 56 5 1240 1247
    • (2007) Diabetes , vol.56 , Issue.5 , pp. 1240-1247
    • Hu, C.M.1    Lin, H.H.2    Chiang, M.T.3    Chang, P.I.F.4    Chau, L.Y.5
  • 171
    • 0037090102 scopus 로고    scopus 로고
    • Genetic control of neutrophil superoxide production in diabetes-resistant ALR/Lt mice
    • DOI 10.1016/S0891-5849(02)00747-5, PII S0891584902007475
    • Mathews C. E., Dunn B. D., Hannigan M. O., Huang C. K., Leiter E. H., Genetic control of neutrophil superoxide production in diabetes-resistant ALR/Lt mice Free Radical Biology and Medicine 2002 32 8 744 751 (Pubitemid 34286595)
    • (2002) Free Radical Biology and Medicine , vol.32 , Issue.8 , pp. 744-751
    • Mathews, C.E.1    Dunn, B.D.2    Hannigan, M.O.3    Huang, C.-K.4    Leiter, E.H.5
  • 174
    • 0029059474 scopus 로고
    • Antioxidant, probucol, can inhibit the generation of hydrogen peroxide in islet cells induced by macrophages and prevent islet cell destruction in NOD mice
    • Fukuda M., Ikegami H., Kawaguchi Y., Sano T., Ogihara T., Antioxidant, probucol, can inhibit the generation of hydrogen peroxide in islet cells induced by macrophages and prevent islet cell destruction in NOD mice Biochemical and Biophysical Research Communications 1995 209 3 953 958
    • (1995) Biochemical and Biophysical Research Communications , vol.209 , Issue.3 , pp. 953-958
    • Fukuda, M.1    Ikegami, H.2    Kawaguchi, Y.3    Sano, T.4    Ogihara, T.5
  • 175
    • 0032544579 scopus 로고    scopus 로고
    • The ortho effect makes manganese(III) meso-tetrakis(N-methylpyridinium- 2-yl)porphyrin a powerful and potentially useful superoxide dismutase mimic
    • DOI 10.1074/jbc.273.38.24521
    • Batini-Haberle I., Benov L., Spasojevi I., Fridovich I., The ortho effect makes manganese(III) meso-tetrakis(N-methylpyridinium- 2-yl)porphyrin a powerful and potentially useful superoxide dismutase mimic Journal of Biological Chemistry 1998 273 38 24521 24528 (Pubitemid 28454947)
    • (1998) Journal of Biological Chemistry , vol.273 , Issue.38 , pp. 24521-24528
    • Batinic-Haberle, I.1    Benov, L.2    Spasojevic, I.3    Fridovich, I.4
  • 177
    • 0033011947 scopus 로고    scopus 로고
    • Metalloporphyrins are potent inhibitors of lipid peroxidation
    • DOI 10.1016/S0891-5849(98)00261-5, PII S0891584998002615
    • Day B. J., Batinic-Haberle I., Crapo J. D., Metalloporphyrins are potent inhibitors of lipid peroxidation Free Radical Biology and Medicine 1999 26 5-6 730 736 (Pubitemid 29146277)
    • (1999) Free Radical Biology and Medicine , vol.26 , Issue.5-6 , pp. 730-736
    • Day, B.J.1    Batinic-Haberle, I.2    Crapo, J.D.3
  • 179
    • 0032547306 scopus 로고    scopus 로고
    • Redox modulation of AP-2 DNA binding activity in vitro
    • DOI 10.1006/bbrc.1998.9139
    • Huang Y., Domann F. E., Redox modulation of AP-2 DNA binding activity in vitro Biochemical and Biophysical Research Communications 1998 249 2 307 312 (Pubitemid 28431749)
    • (1998) Biochemical and Biophysical Research Communications , vol.249 , Issue.2 , pp. 307-312
    • Huang, Y.1    Domann, F.E.2
  • 180
    • 0029760957 scopus 로고    scopus 로고
    • Redox regulation of transcriptional activators
    • DOI 10.1016/0891-5849(96)00109-8
    • Sun YI., Oberley L. W., Redox regulation of transcriptional activators Free Radical Biology and Medicine 1996 21 3 335 348 (Pubitemid 26271723)
    • (1996) Free Radical Biology and Medicine , vol.21 , Issue.3 , pp. 335-348
    • Sun, Y.1    Oberley, L.W.2
  • 181
    • 0034711250 scopus 로고    scopus 로고
    • Protection of human islets from the effects of interleukin-1 by adenoviral gene transfer of an IB repressor
    • DOI 10.1074/jbc.M005943200
    • Giannoukakis N., Rudert W. A., Trucco M., Robbins P. D., Protection of human islets from the effects of interleukin-1 by adenoviral gene transfer of an I B repressor Journal of Biological Chemistry 2000 275 47 36509 36513 (Pubitemid 32002047)
    • (2000) Journal of Biological Chemistry , vol.275 , Issue.47 , pp. 36509-36513
    • Giannoukakis, N.1    Rudert, W.A.2    Trucco, M.3    Robbins, P.D.4
  • 182
    • 0035488777 scopus 로고    scopus 로고
    • Inhibition of Cytokine-Induced NF-B Activation by Adenovirus-Mediated Expression of a NF-B Super-Repressor Prevents -Cell Apoptosis
    • Heimberg H., Heremans Y., Jobin C., Leemans R., Cardozo A. K., Darville M., Eizirik D. L., Inhibition of cytokine-induced NF- B activation by adenovirus-mediated expression of a NF- B super-repressor prevents -cell apoptosis Diabetes 2001 50 10 2219 2224 (Pubitemid 33641904)
    • (2001) Diabetes , vol.50 , Issue.10 , pp. 2219-2224
    • Heimberg, H.1    Heremans, Y.2    Jobin, C.3    Leemans, R.4    Cardozo, A.K.5    Darville, M.6    Eizirik, D.L.7
  • 184
    • 0035865067 scopus 로고    scopus 로고
    • Comparison of a T cell clone and of T cells from a TCR transgenic mouse: TCR transgenic T cells specific for self-antigen are atypical
    • Dobbs C. M., Haskins K., Comparison of a T cell clone and of T cells from a TCR transgenic mouse: TCR transgenic T cells specific for self-antigen are atypical Journal of Immunology 2001 166 4 2495 2504 (Pubitemid 32173486)
    • (2001) Journal of Immunology , vol.166 , Issue.4 , pp. 2495-2504
    • Dobbs, C.M.1    Haskins, K.2
  • 186
    • 0022978272 scopus 로고
    • Effect of antioxidants on primary alloantigen-induced T cell activation and proliferation
    • Chaudhri G., Clark I. A., Hunt N. H., Effect of antioxidants on primary alloantigen-induced T cell activation and proliferation Journal of Immunology 1986 137 8 2646 2652 (Pubitemid 17176624)
    • (1986) Journal of Immunology , vol.137 , Issue.8 , pp. 2646-2652
    • Chaudhri, G.1    Clark, I.A.2    Hunt, N.H.3
  • 187
    • 0023740171 scopus 로고
    • Antioxidants inhibit proliferation and cell surface expression of receptors for interleukin-2 and transferrin in T lymphocytes stimulated with phorbol myristate acetate and ionomycin
    • Chaudhri G., Hunt N. H., Clark I. A., Ceredig R., Antioxidants inhibit proliferation and cell surface expression of receptors for interleukin-2 and transferrin in T lymphocytes stimulated with phorbol myristate acetate and ionomycin Cellular Immunology 1988 115 1 204 213
    • (1988) Cellular Immunology , vol.115 , Issue.1 , pp. 204-213
    • Chaudhri, G.1    Hunt, N.H.2    Clark, I.A.3    Ceredig, R.4
  • 189
    • 0024281396 scopus 로고
    • Diabetes and tolerance in transgenic mice expressing class II MHC molecules in pancreatic beta cells
    • Lo D., Burkly L. C., Widera G., Cowing C., Flavell R. A., Palmiter R. D., Brinster R. L., Diabetes and tolerance in transgenic mice expressing class II MHC molecules in pancreatic beta cells Cell 1988 53 1 159 168
    • (1988) Cell , vol.53 , Issue.1 , pp. 159-168
    • Lo, D.1    Burkly, L.C.2    Widera, G.3    Cowing, C.4    Flavell, R.A.5    Palmiter, R.D.6    Brinster, R.L.7
  • 191
    • 77949899139 scopus 로고    scopus 로고
    • Spontaneous development of endoplasmic reticulum stress that can lead to diabetes mellitus is associated with higher calcium-independent phospholipase A expression: A role for regulation by SREBP-1
    • Lei X., Zhang S., Barbour S. E., Bohrer A., Ford E. L., Koizumi A., Papa F. R., Ramanadham S., Spontaneous development of endoplasmic reticulum stress that can lead to diabetes mellitus is associated with higher calcium-independent phospholipase A expression: a role for regulation by SREBP-1 Journal of Biological Chemistry 2010 285 9 6693 6705
    • (2010) Journal of Biological Chemistry , vol.285 , Issue.9 , pp. 6693-6705
    • Lei, X.1    Zhang, S.2    Barbour, S.E.3    Bohrer, A.4    Ford, E.L.5    Koizumi, A.6    Papa, F.R.7    Ramanadham, S.8
  • 192
    • 0942290632 scopus 로고    scopus 로고
    • 2
    • Ramanadham S., Hsu F.-F., Zhang S., Jin C., Bohrer A., Song H., Bao S., Ma Z., Turk J., Apoptosis of insulin-secreting cells induced by endoplasmic reticulum stress is amplified by overexpression of group VIA calcium-independent phospholipase A2 (iPLA2 beta) and suppressed by inhibition of iPLA2 beta Biochemistry 2004 43 4 918 930 (Pubitemid 38141489)
    • (2004) Biochemistry , vol.43 , Issue.4 , pp. 918-930
    • Ramanadham, S.1    Hsu, F.-F.2    Zhang, S.3    Jin, C.4    Bohrer, A.5    Song, H.6    Bao, S.7    Ma, Z.8    Turk, J.9
  • 193
    • 0344395603 scopus 로고    scopus 로고
    • Bypassing a Kinase Activity with an ATP-Competitive Drug
    • DOI 10.1126/science.1090031
    • Papa F. R., Zhang C., Shokat K., Waiter P., Bypassing a kinase activity with an ATP-competitive drug Science 2003 302 5650 1533 1537 (Pubitemid 37475689)
    • (2003) Science , vol.302 , Issue.5650 , pp. 1533-1537
    • Papa, F.R.1    Zhang, C.2    Shokat, K.3    Waiter, P.4
  • 194
    • 33745891787 scopus 로고    scopus 로고
    • Stressed cells cope with protein overload
    • DOI 10.1126/science.1130469
    • Ron D., Stressed cells cope with protein overload Science 2006 313 5783 52 53 (Pubitemid 44051246)
    • (2006) Science , vol.313 , Issue.5783 , pp. 52-53
    • Ron, D.1
  • 195
    • 0035370949 scopus 로고    scopus 로고
    • Intracellular signaling from the endoplasmic reticulum to the nucleus: The unfolded protein response in yeast and mammals
    • Patil C., Walter P., Intracellular signaling from the endoplasmic reticulum to the nucleus: the unfolded protein response in yeast and mammals Current Opinion in Cell Biology 2001 13 3 349 355
    • (2001) Current Opinion in Cell Biology , vol.13 , Issue.3 , pp. 349-355
    • Patil, C.1    Walter, P.2
  • 196
    • 0037312881 scopus 로고    scopus 로고
    • Dominant negative pathogenesis by mutant proinsulin in the Akita diabetic mouse
    • DOI 10.2337/diabetes.52.2.409
    • Izumi T., Yokota-Hashimoto H., Zhao S., Wang J., Halban P. A., Takeuchi T., Dominant negative pathogenesis by mutant proinsulin in the Akita diabetic mouse Diabetes 2003 52 2 409 416 (Pubitemid 36173197)
    • (2003) Diabetes , vol.52 , Issue.2 , pp. 409-416
    • Izumi, T.1    Yokota-Hashimoto, H.2    Zhao, S.3    Wang, J.4    Halban, P.A.5    Takeuchi, T.6
  • 198
    • 70349352744 scopus 로고    scopus 로고
    • Mechanisms and implications of reactive oxygen species generation during the unfolded protein response: Roles of endoplasmic reticulum oxidoreductases, mitochondrial electron transport, and NADPH oxidase
    • Santos C. X., Tanaka L. Y., Wosniak J., Laurindo F. R., Mechanisms and implications of reactive oxygen species generation during the unfolded protein response: roles of endoplasmic reticulum oxidoreductases, mitochondrial electron transport, and NADPH oxidase Antioxid Redox Signal 2009 11 2409 2427
    • (2009) Antioxid Redox Signal , vol.11 , pp. 2409-2427
    • Santos, C.X.1    Tanaka, L.Y.2    Wosniak, J.3    Laurindo, F.R.4
  • 199
    • 0036853914 scopus 로고    scopus 로고
    • Orchestrating the unfolded protein response in health and disease
    • DOI 10.1172/JCI200216886
    • Kaufman R. J., Orchestrating the unfolded protein response in health and disease Journal of Clinical Investigation 2002 110 10 1389 1398 (Pubitemid 35396907)
    • (2002) Journal of Clinical Investigation , vol.110 , Issue.10 , pp. 1389-1398
    • Kaufman, R.J.1
  • 200
    • 0028881847 scopus 로고
    • DNA-dependent protein kinase is one of a subset of autoantigens specifically cleaved early during apoptosis
    • Casciola-Rosen L. A., Anhalt G. J., Rosen A., DNA-dependent protein kinase is one of a subset of autoantigens specifically cleaved early during apoptosis Journal of Experimental Medicine 1995 182 6 1625 1634
    • (1995) Journal of Experimental Medicine , vol.182 , Issue.6 , pp. 1625-1634
    • Casciola-Rosen, L.A.1    Anhalt, G.J.2    Rosen, A.3
  • 203
    • 0029821899 scopus 로고    scopus 로고
    • Vulnerability of islets in the immediate posttransplantation period: Dynamic changes in structure and function
    • Davalli A. M., Scaglia L., Zangen D. H., Hollister J., Bonner-Weir S., Weir G. C., Vulnerability of islets in the immediate posttransplantation period: dynamic changes in structure and function Diabetes 1996 45 9 1161 1167 (Pubitemid 26296313)
    • (1996) Diabetes , vol.45 , Issue.9 , pp. 1161-1167
    • Davalli, A.M.1    Scaglia, L.2    Zangen, D.H.3    Hollister, J.4    Bonner-Weir, S.5    Weir, G.C.6
  • 205
    • 0026446002 scopus 로고
    • Influence of experimental hyperglycemia on microvascular blood perfusion of pancreatic islet isografts
    • Menger M. D., Vajkoczy P., Leiderer R., Jager S., Messmer K., Influence of experimental hyperglycemia on microvascular blood perfusion of pancreatic islet isografts Journal of Clinical Investigation 1992 90 4 1361 1369
    • (1992) Journal of Clinical Investigation , vol.90 , Issue.4 , pp. 1361-1369
    • Menger, M.D.1    Vajkoczy, P.2    Leiderer, R.3    Jager, S.4    Messmer, K.5
  • 206
    • 0027979555 scopus 로고
    • The beneficial effect of human recombinant superoxide dismutase on acute and chronic rejection events in recipients of cadaveric renal transplants
    • Land W., Schneeberger H., Schleibner S., Illner W. D., Abendroth D., Rutili G., Arfors K. E., Messmer K., The beneficial effect of human recombinant superoxide dismutase on acute and chronic rejection events in recipients of cadaveric renal transplants Transplantation 1994 57 2 211 217 (Pubitemid 24048587)
    • (1994) Transplantation , vol.57 , Issue.2 , pp. 211-217
    • Land, W.1    Schneeberger, H.2    Schleibner, S.3    Illner, W.-D.4    Abendroth, D.5    Rutili, G.6    Arfors, K.E.7    Messmer, K.8
  • 207
    • 0028893293 scopus 로고
    • Do oxygen radicals play a role in primary dysfunction of transplanted livers following preservation in University of Wisconsin solution?
    • Petrowsky H., Dippe B., Geck P., Lincke M., Koenig J., Bhatti S., Wenisch H. J. C., Encke A., Do oxygen radicals play a role in primary dysfunction of transplanted livers following preservation in University of Wisconsin solution? Transplantation Proceedings 1995 27 1 729 731
    • (1995) Transplantation Proceedings , vol.27 , Issue.1 , pp. 729-731
    • Petrowsky, H.1    Dippe, B.2    Geck, P.3    Lincke, M.4    Koenig, J.5    Bhatti, S.6    Wenisch, H.J.C.7    Encke, A.8
  • 208
    • 0024514128 scopus 로고
    • Oxygen free-radical scavengers and immune destruction of murine islets in allograft rejection and multiple low-dose streptozocin-induced insulitis
    • Mendola J., Wright J. R., Lacy P. E., Oxygen free-radical scavengers and immune destruction of murine islets in allograft rejection and multiple low-dose streptozocin-induced insulitis Diabetes 1989 38 3 379 385 (Pubitemid 19071480)
    • (1989) Diabetes , vol.38 , Issue.3 , pp. 379-385
    • Mendola, J.1    Wright, J.R.2    Lacy, P.E.3
  • 210
    • 33750066303 scopus 로고    scopus 로고
    • Protection of human islets from induction of apoptosis and improved islet function with HO-1 gene transduction
    • Li Y. X., Li GE., Dong W. P., Lu DA. R., Tan J. M., Protection of human islets from induction of apoptosis and improved islet function with HO-1 gene transduction Chinese Medical Journal 2006 119 19 1639 1645
    • (2006) Chinese Medical Journal , vol.119 , Issue.19 , pp. 1639-1645
    • Li, Y.X.1    Li, G.E.2    Dong, W.P.3    Lu, D.A.R.4    Tan, J.M.5
  • 211
    • 0037315583 scopus 로고    scopus 로고
    • Gene transfer of manganese superoxide dismutase extends islet graft function in a mouse model of autoimmune diabetes
    • DOI 10.2337/diabetes.52.2.387
    • Bertera S., Crawford M. L., Alexander A. M., Papworth G. D., Watkins S. C., Robbins P. D., Trucco M., Gene transfer of manganese superoxide dismutase extends islet graft function in a mouse model of autoimmune diabetes Diabetes 2003 52 2 387 393 (Pubitemid 36173194)
    • (2003) Diabetes , vol.52 , Issue.2 , pp. 387-393
    • Bertera, S.1    Crawford, M.L.2    Alexander, A.M.3    Papworth, G.D.4    Watkins, S.C.5    Robbins, P.D.6    Trucco, M.7
  • 212
    • 0036328572 scopus 로고    scopus 로고
    • Preservation of human islet cell functional mass by anti-oxidative action of a novel SOD mimic compound
    • Bottino R., Balamurugan A. N., Bertera S., Pietropaolo M., Trucco M., Piganelli J. D., Preservation of human islet cell functional mass by anti-oxidative action of a novel SOD mimic compound Diabetes 2002 51 8 2561 2567 (Pubitemid 34827407)
    • (2002) Diabetes , vol.51 , Issue.8 , pp. 2561-2567
    • Bottino, R.1    Balamurugan, A.N.2    Bertera, S.3    Pietropaolo, M.4    Trucco, M.5    Piganelli, J.D.6
  • 213
    • 33646692209 scopus 로고    scopus 로고
    • Prospective and challenges of islet transplantation for the therapy of autoimmune diabetes
    • Balamurugan A. N., Bottino R., Giannoukakis N., Smetanka C., Prospective and challenges of islet transplantation for the therapy of autoimmune diabetes Pancreas 2006 32 3 231 243
    • (2006) Pancreas , vol.32 , Issue.3 , pp. 231-243
    • Balamurugan, A.N.1    Bottino, R.2    Giannoukakis, N.3    Smetanka, C.4
  • 214
    • 33750583959 scopus 로고    scopus 로고
    • Sirolimus is associated with reduced islet engraftment and impaired -cell function
    • DOI 10.2337/db06-0173
    • Zhang N., Su D., Qu S., Tse T., Bottino R., Balamurugan A. N., Xu J., Bromberg J. S., Dong H. H., Sirolimus is associated with reduced islet engraftment and impaired -cell function Diabetes 2006 55 9 2429 2436 (Pubitemid 44871142)
    • (2006) Diabetes , vol.55 , Issue.9 , pp. 2429-2436
    • Zhang, N.1    Su, D.2    Qu, S.3    Tse, T.4    Bottino, R.5    Balamurugan, A.N.6    Xu, J.7    Bromberg, J.S.8    Dong, H.H.9
  • 215
    • 77952480033 scopus 로고    scopus 로고
    • Role of reactive oxygen species in the progression of type 2 diabetes and atherosclerosis
    • Kaneto H., Katakami N., Matsuhisa M., Matsuoka T. A., Role of reactive oxygen species in the progression of type 2 diabetes and atherosclerosis Mediators of Inflammation 2010 2010
    • (2010) Mediators of Inflammation , vol.2010
    • Kaneto, H.1    Katakami, N.2    Matsuhisa, M.3    Matsuoka, T.A.4
  • 216
    • 77949906856 scopus 로고    scopus 로고
    • Myelin basic protein priming reduces the expression of Foxp3 in T cells via nitric oxide
    • Brahmachari S., Pahan K., Myelin basic protein priming reduces the expression of Foxp3 in T cells via nitric oxide Journal of Immunology 2010 184 4 1799 1809
    • (2010) Journal of Immunology , vol.184 , Issue.4 , pp. 1799-1809
    • Brahmachari, S.1    Pahan, K.2
  • 217
    • 52649102593 scopus 로고    scopus 로고
    • Complications of type 1 diabetes: New molecular findings
    • Stirban A., Rsen P., Tschoepe D., Complications of type 1 diabetes: new molecular findings Mount Sinai Journal of Medicine 2008 75 4 328 351
    • (2008) Mount Sinai Journal of Medicine , vol.75 , Issue.4 , pp. 328-351
    • Stirban, A.1    Rsen, P.2    Tschoepe, D.3
  • 219
    • 0034527752 scopus 로고    scopus 로고
    • Vitamin E and leukocyte-endothelial cell interactions
    • Yoshikawa T., Yoshida N., Vitamin E and leukocyte-endothelial cell interactions Antioxidants and Redox Signaling 2000 2 4 821 825 (Pubitemid 32062331)
    • (2000) Antioxidants and Redox Signaling , vol.2 , Issue.4 , pp. 821-825
    • Yoshikawa, T.1    Yoshida, N.2


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