메뉴 건너뛰기




Volumn 48, Issue 12, 1999, Pages 2398-2406

Beneficial effects of antioxidants in diabetes: Possible protection of pancreatic β-cells against glucose toxicity

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCYSTEINE; ALPHA TOCOPHEROL; ASCORBIC ACID;

EID: 0033499583     PISSN: 00121797     EISSN: None     Source Type: Journal    
DOI: 10.2337/diabetes.48.12.2398     Document Type: Article
Times cited : (623)

References (44)
  • 1
    • 0026110135 scopus 로고
    • Banting lecture 1990: β-cells in type II diabetes mellitus
    • Porte D Jr: Banting lecture 1990: β-cells in type II diabetes mellitus. Diabetes 40:166-180, 1991
    • (1991) Diabetes , vol.40 , pp. 166-180
    • Porte D., Jr.1
  • 3
    • 0026731869 scopus 로고
    • Glucose toxicity
    • Yki-Jarvinen H: Glucose toxicity. Endocrine Rev 13:415-431, 1992
    • (1992) Endocrine Rev , vol.13 , pp. 415-431
    • Yki-Jarvinen, H.1
  • 4
    • 0030017385 scopus 로고    scopus 로고
    • Determinants of pancreatic islet cell mass: A balance between neogenesis and senescence/apoptosis
    • Vinik A, Pittenger G, Rafaeloff R, Rosenberg L, Duguid W: Determinants of pancreatic islet cell mass: a balance between neogenesis and senescence/apoptosis. Diabetes Rev 4:235-263, 1996
    • (1996) Diabetes Rev , vol.4 , pp. 235-263
    • Vinik, A.1    Pittenger, G.2    Rafaeloff, R.3    Rosenberg, L.4    Duguid, W.5
  • 6
    • 0026757632 scopus 로고
    • Preservation of insulin mRNA levels and insulin secretion in HIT cells by avoidance of chronic exposure to high glucose concentrations
    • Robertson RP, Zhang H-J, Pyzdrowski KL, Walseth TF: Preservation of insulin mRNA levels and insulin secretion in HIT cells by avoidance of chronic exposure to high glucose concentrations. J Clin Invest 90:320-325, 1992
    • (1992) J Clin Invest , vol.90 , pp. 320-325
    • Robertson, R.P.1    Zhang, H.-J.2    Pyzdrowski, K.L.3    Walseth, T.F.4
  • 7
    • 0027237191 scopus 로고
    • Chronic exposure of HIT cells to high glucose concentrations paradoxically decreases insulin gene transcription and alters binding of insulin gene regulatory protein
    • Olson LK, Redmon JB, Towle HC, Robertson RP: Chronic exposure of HIT cells to high glucose concentrations paradoxically decreases insulin gene transcription and alters binding of insulin gene regulatory protein. J Clin Invest 92:514-519, 1993
    • (1993) J Clin Invest , vol.92 , pp. 514-519
    • Olson, L.K.1    Redmon, J.B.2    Towle, H.C.3    Robertson, R.P.4
  • 8
    • 0029086781 scopus 로고
    • The reduction of insulin gene transcription in HIF-T15β cells chronically exposed to high glucose concentration is associated with loss of RIPE3b 1 and STF-1 transcription factor expression
    • Sharma A, Olson LK, Robertson RP, Stein R: The reduction of insulin gene transcription in HIF-T15β cells chronically exposed to high glucose concentration is associated with loss of RIPE3b 1 and STF-1 transcription factor expression. Mol Endocrinol 9:1127-1134, 1995
    • (1995) Mol Endocrinol , vol.9 , pp. 1127-1134
    • Sharma, A.1    Olson, L.K.2    Robertson, R.P.3    Stein, R.4
  • 9
    • 0029664752 scopus 로고    scopus 로고
    • Chronic exposure of βTc-6 cells to supraphysiologic concentrations of glucose decreases binding of the RIPE3b1 insulin gene transcription activator
    • Poitout V, Olson LK, Robertson RP: Chronic exposure of βTC-6 cells to supraphysiologic concentrations of glucose decreases binding of the RIPE3b1 insulin gene transcription activator. J Clin Invest 97:1041-1046, 1996
    • (1996) J Clin Invest , vol.97 , pp. 1041-1046
    • Poitout, V.1    Olson, L.K.2    Robertson, R.P.3
  • 10
    • 0030762209 scopus 로고    scopus 로고
    • Differentiation of glucose toxicity from beta cell exhaustion during the evolution of defective insulin gene expression in the pancreatic islet cell line, HIT-T15
    • Moran A, Zhang H-J, Olson LK, Harmon JS, Poitout V, Robertson RP: Differentiation of glucose toxicity from beta cell exhaustion during the evolution of defective insulin gene expression in the pancreatic islet cell line, HIT-T15. J Clin Invest 99:534-539, 1997
    • (1997) J Clin Invest , vol.99 , pp. 534-539
    • Moran, A.1    Zhang, H.-J.2    Olson, L.K.3    Harmon, J.S.4    Poitout, V.5    Robertson, R.P.6
  • 11
    • 0027384997 scopus 로고
    • IPF1, a homeodomain-containing-transactivator of the insulin gene
    • Ohlsson H, Karlsson K, Edlund T: IPF1, a homeodomain-containing-transactivator of the insulin gene. EMBO J 12:4251-4259, 1993
    • (1993) EMBO J , vol.12 , pp. 4251-4259
    • Ohlsson, H.1    Karlsson, K.2    Edlund, T.3
  • 12
    • 0027373441 scopus 로고
    • Characterization of somatostatin transactivating factor-1, a novel homeobox factor that stimulates somatostatin expression in pancreatic islet cells
    • Leonard J, Peers B, Johnson T, Ferreri K, Lee S, Montminy MR: Characterization of somatostatin transactivating factor-1, a novel homeobox factor that stimulates somatostatin expression in pancreatic islet cells. Mol Endocrinol 7:1275-1283, 1993
    • (1993) Mol Endocrinol , vol.7 , pp. 1275-1283
    • Leonard, J.1    Peers, B.2    Johnson, T.3    Ferreri, K.4    Lee, S.5    Montminy, M.R.6
  • 13
    • 0028314969 scopus 로고
    • IDX-1: A new homeodomain transcription factor expressed in rat pancreatic islets and duodenum that transactivates the somatostatin gene
    • Miller CP, McGehee RE, Habener JF: IDX-1: a new homeodomain transcription factor expressed in rat pancreatic islets and duodenum that transactivates the somatostatin gene. EMBO J 13:1145-1156, 1994
    • (1994) EMBO J , vol.13 , pp. 1145-1156
    • Miller, C.P.1    McGehee, R.E.2    Habener, J.F.3
  • 14
    • 0030904248 scopus 로고    scopus 로고
    • Homeodomain protein IDX-1: A master regulator of pancreas development and insulin gene expression
    • Stoffers DA, Thomas MK, Habener JF: Homeodomain protein IDX-1: a master regulator of pancreas development and insulin gene expression. Trends Endocrinol Metab 8:145-151, 1997
    • (1997) Trends Endocrinol Metab , vol.8 , pp. 145-151
    • Stoffers, D.A.1    Thomas, M.K.2    Habener, J.F.3
  • 15
    • 0030656344 scopus 로고    scopus 로고
    • Transcription factor abnormalities as a cause of beta cell dysfunction in diabetes: A hypothesis
    • Weir GC, Sharma A, Zangen DH, Bonner-Weir S: Transcription factor abnormalities as a cause of beta cell dysfunction in diabetes: a hypothesis. Acta Diabetol 34:177-184, 1997
    • (1997) Acta Diabetol , vol.34 , pp. 177-184
    • Weir, G.C.1    Sharma, A.2    Zangen, D.H.3    Bonner-Weir, S.4
  • 16
    • 0029909387 scopus 로고    scopus 로고
    • The human glucokinase gene β-cell-type promoter an essential role of insulin promoter factor 1 (IPF1)/PDX-1 in its activation in HIT-T15 cells
    • Watada H, Kajimoto Y, Umayahara Y, Matsuoka T, Kaneto H, Fujitani Y, Kamada Y, Kawamori R, Yamasaki Y: The human glucokinase gene β-cell-type promoter an essential role of insulin promoter factor 1 (IPF1)/PDX-1 in its activation in HIT-T15 cells. Diabetes 45:1478-1488, 1996
    • (1996) Diabetes , vol.45 , pp. 1478-1488
    • Watada, H.1    Kajimoto, Y.2    Umayahara, Y.3    Matsuoka, T.4    Kaneto, H.5    Fujitani, Y.6    Kamada, Y.7    Kawamori, R.8    Yamasaki, Y.9
  • 17
    • 0030457705 scopus 로고    scopus 로고
    • Transcriptional activation of the GLUT2 gene by the IPF-1/STF-1/IDX-1 homeobox factor
    • Waeber G, Thompson N, Nicod P, Bonny C: Transcriptional activation of the GLUT2 gene by the IPF-1/STF-1/IDX-1 homeobox factor. Mol Endocrinol 10:1327-1334, 1996
    • (1996) Mol Endocrinol , vol.10 , pp. 1327-1334
    • Waeber, G.1    Thompson, N.2    Nicod, P.3    Bonny, C.4
  • 19
    • 0023755121 scopus 로고
    • Superoxide production from nonenzymatically glycation protein
    • Sakurai T, Tsuchiya S: Superoxide production from nonenzymatically glycation protein. FEBS Lett 236:406-410, 1988
    • (1988) FEBS Lett , vol.236 , pp. 406-410
    • Sakurai, T.1    Tsuchiya, S.2
  • 20
    • 0025096104 scopus 로고
    • Autoxidative glycosylation and possible involvement of peroxides and free radicals in LDL modification by glucose
    • Hunt JV, Smith CC, Wolff SP: Autoxidative glycosylation and possible involvement of peroxides and free radicals in LDL modification by glucose. Diabetes 39:1420-1424, 1991
    • (1991) Diabetes , vol.39 , pp. 1420-1424
    • Hunt, J.V.1    Smith, C.C.2    Wolff, S.P.3
  • 21
    • 0028800370 scopus 로고
    • Immunological detection of glycated proteins in normal and streptozotocin-induced diabetic rats using anti hexitol-lysine IgG
    • Myint T, Hoshi S, Ookawara T, Miyazawa N, Suzuki K, Taniguchi N: Immunological detection of glycated proteins in normal and streptozotocin-induced diabetic rats using anti hexitol-lysine IgG. Biochem Biophys Acta 1272:73-79, 1995
    • (1995) Biochem Biophys Acta , vol.1272 , pp. 73-79
    • Myint, T.1    Hoshi, S.2    Ookawara, T.3    Miyazawa, N.4    Suzuki, K.5    Taniguchi, N.6
  • 22
    • 0025732948 scopus 로고
    • Role of oxidative stress in development of complications in diabetes
    • Baynes JW: Role of oxidative stress in development of complications in diabetes. Diabetes 40:405-412, 1991
    • (1991) Diabetes , vol.40 , pp. 405-412
    • Baynes, J.W.1
  • 24
    • 0031025828 scopus 로고    scopus 로고
    • Long term effects of aminoguanidine on insulin release and biosynthesis: Evidence that the formation of advanced glycosylation end products inhibits B cell function
    • Tajiri Y, Moller C, Grill V: Long term effects of aminoguanidine on insulin release and biosynthesis: evidence that the formation of advanced glycosylation end products inhibits B cell function. Endocrinology 138:273-280, 1997
    • (1997) Endocrinology , vol.138 , pp. 273-280
    • Tajiri, Y.1    Moller, C.2    Grill, V.3
  • 26
    • 0030689041 scopus 로고    scopus 로고
    • Relation between antioxidant enzyme gene expression and antioxidative defense status of insulin-producing cells
    • Tiedge M, Lortz S, Drinkgern J, Lenzen S: Relation between antioxidant enzyme gene expression and antioxidative defense status of insulin-producing cells. Diabetes 46:1733-1742, 1997
    • (1997) Diabetes , vol.46 , pp. 1733-1742
    • Tiedge, M.1    Lortz, S.2    Drinkgern, J.3    Lenzen, S.4
  • 28
    • 0030930677 scopus 로고    scopus 로고
    • Antioxidant defense: Vitamins E and C and carotenoids
    • Stahl W, Sies H: Antioxidant defense: vitamins E and C and carotenoids. Diabetes 46 (Suppl. 2):14-18, 1997
    • (1997) Diabetes , vol.46 , Issue.SUPPL. 2 , pp. 14-18
    • Stahl, W.1    Sies, H.2
  • 29
    • 0014004384 scopus 로고
    • Diabetes, a new mutation in the mouse
    • Hummel KP, Dick MM, Coleman DL: Diabetes, a new mutation in the mouse. Science 153:1127-1128, 1966
    • (1966) Science , vol.153 , pp. 1127-1128
    • Hummel, K.P.1    Dick, M.M.2    Coleman, D.L.3
  • 30
    • 0014076277 scopus 로고
    • Studies with the mutation, diabetes, in the mouse
    • Coleman DL, Hummel KP: Studies with the mutation, diabetes, in the mouse. Diabetologia 3:238-248, 1966
    • (1966) Diabetologia , vol.3 , pp. 238-248
    • Coleman, D.L.1    Hummel, K.P.2
  • 33
    • 0031913829 scopus 로고    scopus 로고
    • Role of apoptosis in failure of β-cell mass compensation for insulin resistance and β-cell defects in the male Zucker diabetic fatty rat
    • Pick A, Clark J, Kubstrup C, Levisetti M, Pugh W, Bonner-Weir S, Polonsky KS: Role of apoptosis in failure of β-cell mass compensation for insulin resistance and β-cell defects in the male Zucker diabetic fatty rat. Diabetes 47:358-364, 1998
    • (1998) Diabetes , vol.47 , pp. 358-364
    • Pick, A.1    Clark, J.2    Kubstrup, C.3    Levisetti, M.4    Pugh, W.5    Bonner-Weir, S.6    Polonsky, K.S.7
  • 34
    • 0031683542 scopus 로고    scopus 로고
    • Prolonged oxidative stress impairs insulin-induced GLUT4 translocation in 3T3-L1 adipocytes
    • Rudich A, Tirosh A, Potashnik R, Hemi R, Kanety H, Bashan N: Prolonged oxidative stress impairs insulin-induced GLUT4 translocation in 3T3-L1 adipocytes. Diabetes 47:1562-1569, 1998
    • (1998) Diabetes , vol.47 , pp. 1562-1569
    • Rudich, A.1    Tirosh, A.2    Potashnik, R.3    Hemi, R.4    Kanety, H.5    Bashan, N.6
  • 35
    • 0033034807 scopus 로고    scopus 로고
    • Hyperglycemia-induced β-cell apoptosis in pancreatic islets of Psammomys obesus during development of diabetes
    • Donath MY, Gross DJ, Cerasi E, Kaiser N: Hyperglycemia-induced β-cell apoptosis in pancreatic islets of Psammomys obesus during development of diabetes. Diabetes 48:783-744, 1999
    • (1999) Diabetes , vol.48 , pp. 783-1744
    • Donath, M.Y.1    Gross, D.J.2    Cerasi, E.3    Kaiser, N.4
  • 36
    • 0028845665 scopus 로고
    • Apoptosis contributes to the involution of β cell mass in the post partum rat pancreas
    • Scaglia L, Smith FE, Bonner-Weir S: Apoptosis contributes to the involution of β cell mass in the post partum rat pancreas. Endocrinology 136:5461-5468, 1995
    • (1995) Endocrinology , vol.136 , pp. 5461-5468
    • Scaglia, L.1    Smith, F.E.2    Bonner-Weir, S.3
  • 37
    • 0028149890 scopus 로고
    • Insulin-promoter-factor 1 is required for pancreas development in mice
    • Jonsson J, Carlsson L, Edlund T, Edlund H: Insulin-promoter-factor 1 is required for pancreas development in mice. Nature 37:606-609, 1994
    • (1994) Nature , vol.37 , pp. 606-609
    • Jonsson, J.1    Carlsson, L.2    Edlund, T.3    Edlund, H.4
  • 41
    • 0031031571 scopus 로고    scopus 로고
    • Pancreatic agenesis attributable to a single nucleotide deletion in the human IPF1 gene coding sequence
    • Stoffers DA, Zinkin NT, Stanojevic V, Clarke WL, Habener JF: Pancreatic agenesis attributable to a single nucleotide deletion in the human IPF1 gene coding sequence. Nat Genet 15:106-110, 1997
    • (1997) Nat Genet , vol.15 , pp. 106-110
    • Stoffers, D.A.1    Zinkin, N.T.2    Stanojevic, V.3    Clarke, W.L.4    Habener, J.F.5
  • 42
    • 0031253820 scopus 로고    scopus 로고
    • Early-onset type-II diabetes mellitus (MODY4) linked to IPF1
    • Stoffers DA, Ferrer J, Clarke WL, Habener JF: Early-onset type-II diabetes mellitus (MODY4) linked to IPF1. Nat Genet 17:138-139, 1997
    • (1997) Nat Genet , vol.17 , pp. 138-139
    • Stoffers, D.A.1    Ferrer, J.2    Clarke, W.L.3    Habener, J.F.4
  • 44
    • 0030022084 scopus 로고    scopus 로고
    • Inhibition with N-acetylcysteine of development of peripheral neuropathy in streptozotocin-induced diabetic rats
    • Sagara M, Satoh J, Wada R, Yagihashi S, Takahashi K, Fukuzawa M, Muto G, Toyota T: Inhibition with N-acetylcysteine of development of peripheral neuropathy in streptozotocin-induced diabetic rats. Diabetologia 39:263-269, 1996
    • (1996) Diabetologia , vol.39 , pp. 263-269
    • Sagara, M.1    Satoh, J.2    Wada, R.3    Yagihashi, S.4    Takahashi, K.5    Fukuzawa, M.6    Muto, G.7    Toyota, T.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.