Diabetes associated cell stress and dysfunction: Role of mitochondrial and non-mitochondrial ROS production and activity

Journal of Physiology

Volumn 583, Issue 1, 2007, Pages 9-24

  Newsholme, Philip ^a   Haber, E P ^b   Hirabara, S M ^c   Rebelato, E L O ^c   Procopio, J ^c   Morgan, D ^c   Oliveira Emilio, H C ^d   Carpinelli, A R ^c   Curi, R ^c  

^a UNIVERSITY COLLEGE DUBLIN   (Ireland)

^b HADASSAH HEBREW UNIVERSITY MEDICAL CENTER   (Israel)

^c UNIVERSITY OF SÃO PAULO   (Brazil)

^d STATE UNIVERSITY OF PONTA GROSSA   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE; ANGIOTENSIN II; CALCIUM ION; CASPASE 9; CATALASE; GLUCOSE TRANSPORTER 1; GLUCOSE TRANSPORTER 2; GLUTATHIONE PEROXIDASE; GUANYLATE CYCLASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; INSULIN; INSULIN RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE P38; PLATELET DERIVED GROWTH FACTOR; PROTEIN BCL 2; PROTEIN KINASE B; PROTEIN KINASE C; PYRUVATE DEHYDROGENASE; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 2; STRESS ACTIVATED PROTEIN KINASE; SUPEROXIDE DISMUTASE; THIOREDOXIN; THROMBIN; TUMOR NECROSIS FACTOR ALPHA; UNCOUPLING PROTEIN; UNINDEXED DRUG; VOLTAGE GATED CALCIUM CHANNEL; FATTY ACID; GLUCOSE; MITOCHONDRIAL PROTEIN;

CALCIUM TRANSPORT; CELL DEATH; CELL PROLIFERATION; CELL STRESS; DIABETES MELLITUS; DIABETOGENESIS; DRUG TARGETING; ENERGY METABOLISM; ENZYME ACTIVITY; HORMONE ACTION; HUMAN; INSULIN RELEASE; INSULIN RESISTANCE; MITOCHONDRIAL RESPIRATION; MITOCHONDRION; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; OXIDATIVE STRESS; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; REVIEW; SIGNAL TRANSDUCTION; CELL DAMAGE; CELL ENERGY; CELL FUNCTION; CELL METABOLISM; CELLS; GLUCOLIPOTOXICITY; INSULIN ACTION; INSULIN SENSITIVE CELL; LIPOTOXICITY; RESPIRATORY CHAIN;

ANIMALS; APOPTOSIS; DIABETES MELLITUS, TYPE 2; HUMANS; INSULIN RESISTANCE; INSULIN-SECRETING CELLS; MITOCHONDRIA; NADPH OXIDASE; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES;

EID: 34547830983     PISSN: 00223751     EISSN: 14697793     Source Type: Journal    
DOI: 10.1113/jphysiol.2007.135871     Document Type: Review

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