Targeted overexpression of Cu/Zn superoxide dismutase protects pancreatic β-cells against oxidative stress

Diabetes

Volumn 46, Issue 10, 1997, Pages 1563-1566

  Kubisch, H Michael ^a   Wang, Junqiang ^a   Bray, Tammy M ^a   Phillips, John P ^a  

^a UNIVERSITY OF GUELPH   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

COPPER ZINC SUPEROXIDE DISMUTASE; REACTIVE OXYGEN METABOLITE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOIMMUNITY; CELL KILLING; DIABETOGENESIS; DISEASE PREDISPOSITION; ENZYME ACTIVITY; GENE EXPRESSION; MOUSE; NONHUMAN; OXIDATIVE STRESS; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL;

EID: 0030798658     PISSN: 00121797     EISSN: None     Source Type: Journal    
DOI: 10.2337/diabetes.46.10.1563     Document Type: Article

References (43)

1. Eisenbarth GS: Type I diabetes mellitus, a chronic autoimmune disease. N Engl J Med 314:1360-1368, 1986
2. Tisch R, McDevitt H: Insulin-dependent diabetes mellitus. Cell 85:291-297, 1996
3. Jacob HJ, Pettersson A, Wilson D, Mao Y, Lernmark A, Lander ES: Genetic dissection of autoimmune type 1 diabetes in the BB rat. Nature Genet 2:56-60, 1994
4. Hanafusa T, Tarui S: Immune pathogenesis of diabetes in the nonobese diabetic mouse: an overview. Curr Top Microbiol Immunol 164:15-25, 1990
5. Mandrup-Poulson T, Helqvist S, Wogensen LD, Molvig J, Pociot F, Johanneson J, Nerup J: Cytokines and free radicals as effector molecules in the destruction of pancreatic beta cells. Curr Top Microbiol Immunol 164:169-193, 1990
6. Corbett JA, McDaniel ML: Does nitric oxide mediate autoimmune destruction of β-cells? Diabetes 41:897-903 1992
7. Oberley LW: Free radicals and diabetes. Free Radic Biol Med 5:113-124, 1988
8. Lenzen S, Drinkgern J, Tiedge M: Low antioxidant enzyme gene expression in pancreatic islets compared with various other mouse tissues. Free Radic Biol Med 20:463-466, 1996
9. Malaisse WJ, Malaisse-Lagae F, Sener A, Pipeleers DG: Determinants of the selective toxicity of alloxan to the pancreatic β cell. Proc Natl Acad Sci USA 79:927-930, 1982
10. Gandy SE, Galbraith RA, Crouch RK, Buse MG, Galbraith GM: Superoxide dismutase in human islets of Langerhans. N Engl J Med 204:1547-1548, 1981
11. Grankvist K, Marklund S, Taljedal I: CuZn-superoxide dismutase, Mn superoxide dismutase, catalase and glutathione peroxidase in pancreatic islets and other tissues in the mouse. Biochem J 199:393-398, 1981
12. Sandler S, Andersson A: The partial protective effect of the hydroxyl radical scavenger dimethyl urea on streptozotocin-induced diabetes in the mouse in vivo and in vitro. Diabetologia 23:374-378, 1981
13. Sandler S, Welsh M, Andersson A: Streptozotocin-induced impairment of islet-cell metabolism and its prevention by a hydroxyl radical scavenger and inhibitors of poly (ADP ribose) synthetase. Acta Pharmacol Toxicol 53:392-400, 1983
14. Mendola J, Wright JR, Lacy PE: Oxygen free radical scavengers and immune destruction of murine islets in allograft rejection and multiple low-dose streptozotocin. Diabetes 38:379-385, 1989
15. Fischer LJ, Hamberger SA: Inhibition of alloxan action in isolated pancreatic islets by Superoxide dismutase, catalase and a metal chelator. Diabetes 29:213-216, 1980
16. Gandy SE, Buse MG, Crouch RK: Protective role of Superoxide dismutase against diabetogenic drugs. J Clin Invest 70:650-658, 1982
17. 2 radicals in autoimmune diabetes. Immunol Cell Biol 67:85-87, 1989
18. Robbins MJ, Sharp RA, Slonim AE, Burr IM: Protection against streptozotocin-induced diabetes by Superoxide dismutase. Diabetologia 18:55-58, 1980
19. Sumoski W, Baquerizo H, Rabinovich A: Oxygen free radical scavengers protect rat islet cells from damage by cytokines. Diabetologia 32:792-796, 1989
20. Yamada K, Nonaka K, Hanafusa T, Miyazaki A, Toyoshima H, Tarui S: Preventative and therapeutic effects of large dose nicotinamide injections on diabetes associated with insulitis: an observation in non-obese diabetic (NOD) mice. Diabetes 31:749-753, 1982
21. Drash A., Rudert WA, Borguaye S, Wang R, Lieberman I: Effect of probucol on development of diabetes mellitus in BB rats. Am J Cardiol 62:27B-30B 1988
22. Beckman JS: The double-edged role of nitric oxide in brain function and superoxide-mediated injury. J Develop Physiol 15:53-59, 1991
23. Ischiropoulos H, Zhu L, Beckman JS: Peroxynitrite formation from macrophage-derived nitric oxide. Arch Biochem Biophys 298:446-451, 1992
24. Corbett JA, Tilton RG, Chang K, Hasan KS, Ido Y, Wang JL, Sweetland MA, Lancaster JR Jr, Williamson JR, McDaniel ML: Aminoguanidine, a novel inhibitor of nitric oxide formation, prevents diabetic vascular dysfunction. Diabetes 41:552-556, 1992
25. Kolb H, Kiesel U, Kroncke K-D, Kolb-Bachofen V: Suppression of low dose streptozotocin-induced diabetes in mice by administration of a nitric oxide synthase inhibitor. Life Sci 49:213-217, 1991
26. Kolb H, Kolb-Bachofen V: Type-1 (insulin-dependent) diabetes mellitus and nitric oxide. Diabetologia 35:796-797, 1992
27. Lukic ML, Stosic-Grujicic S, Ostojic N, Chan WL, Liew FY: Inhibition of nitric oxide generation affects the induction of diabetes by streptozotocin in mice. Biochem Biophys Res Commun 178:913-820, 1991
28. Kubisch HM, Wang J, Luche R, Carlson E, Bray TM, Epstein CJ, Phillips JP: Transgenic copper/zinc Superoxide dismutase modulates susceptibility to type 1 diabetes. Proc Natl Acad Sci USA 91:9956-9959, 1994
29. Hanahan D: Heritable formation of pancreatic β-cell tumours in transgenic mice expressing insulin/simian virus 40 oncogenes. Nature 315:115-122, 1985
30. Hogan B, Costantini F, Lacy E: Manipulating the Mouse Embryo. Cold Spring Harbor, NY, Cold Spring Harbor Laboratory, 1986
31. McCord JM, Fridovich I: Superoxide dismutase: an enzymatic function for erythrocuprein. J Biol Chem 244:256-275, 1969
32. Seto NOL, Hayashi S, Tener GM: Drosophila Cu-Zn Superoxide dismutase cDNA sequence. Nucleic Acids Res 15:5483, 1987
33. Lee YM, Ayala FJ, Misra HP: Purification and properties of Superoxide dismutases from Drosophila melanogaster. J Biol Chem 256:8506-8509, 1981
34. Rerup CC: Drugs producing diabetes through damage of the insulin secreting cells. Pharmacol Rev 22:485-518, 1970
35. Cornelius JG, Luttage BG, Peck AB: Antioxidant enzyme activities in IDD-prone and IDD-resistant mice: a comparative study. Free Radic Biol Med 14:409-420, 1993
36. Ohashi PS, Oehen S, Buerki K, Pircher H, Ohashi CT, Odermatt B, Malissen B, Zinkernagel RM, Hengartner H: Ablation of "tolerance" and induction of diabetes by virus infection in viral antigen transgenic mice. Cell 65:305-317, 1991
37. Oldstone MBA, Nerenberg M, Southern P, Price J, Lewicki H: Virus infection triggers insulin-dependent diabetes mellitus in a transgenic model: role of antiself (virus) immune response. Cell 65:319-331, 1991
38. Sarvetnick N, Liggitt D, Pitts SL, Hansen SE, Stewart TA: Insulin-dependent diabetes mellitus induced in transgenic mice by ectopic expression of class II MHC and interferon-gamma. Cell 52:773-782, 1988
39. Sarvetnick N, Shizuru J, Liggett D, Martin L, McIntyre B, Gregory A, Parslow T, Stewart T: Loss of pancreatic islet tolerance induced by β-cell expression of interferon-γ. Nature 346:844-847, 1990
40. Stewart TA, Hultgren B, Huang X, Pitts-Meek S, Hully J, MacLachlan NJ: Induction of type I diabetes by interferon-α in transgenic mice. Science 260:1942-1946, 1993
41. Castano L, Eisenbarth GS: Type-I diabetes: a chronic autoimmune disease of human, mouse and rat. Ann Rev Immunol 8:647-679, 1990
42. Hanafusa T, Tarui S: Immune pathogenesis of diabetes in the nonobese diabetic mouse: an overview. Curr Top Microbiol Immunol 156:15-25, 1990
43. Katz JD, Wang B, Haskins K, Benoist C, Mathis D: Following a diabetogenic T cell from genesis through pathogenesis. Cell 74:1089-1100, 1993