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Volumn 50, Issue 1, 2011, Pages 115-131

Functional and pathological roles of the 12- and 15-lipoxygenases

Author keywords

12 15 Lipoxygenase; Adipose tissue; Arachidonic acid; Atherosclerosis; Inflammation; Kidney; Obesity; Pancreatic islet

Indexed keywords

ARACHIDONATE 12 LIPOXYGENASE; ARACHIDONATE 15 LIPOXYGENASE; FATTY ACID;

EID: 78650698895     PISSN: 01637827     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.plipres.2010.10.005     Document Type: Review
Times cited : (272)

References (232)
  • 1
    • 0034221273 scopus 로고    scopus 로고
    • Human requirement for N-3 polyunsaturated fatty acids
    • A.P. Simopoulos Human requirement for N-3 polyunsaturated fatty acids Poult Sci 79 2000 961 970
    • (2000) Poult Sci , vol.79 , pp. 961-970
    • Simopoulos, A.P.1
  • 3
    • 0037821818 scopus 로고    scopus 로고
    • Nitric oxide triggers the toxicity due to glutathione depletion in midbrain cultures through 12-lipoxygenase
    • S. Canals, M.J. Casarejos, S. de Bernardo, E. Rodriguez-Martin, and M.A. Mena Nitric oxide triggers the toxicity due to glutathione depletion in midbrain cultures through 12-lipoxygenase J Biol Chem 278 2003 21542 21549
    • (2003) J Biol Chem , vol.278 , pp. 21542-21549
    • Canals, S.1    Casarejos, M.J.2    De Bernardo, S.3    Rodriguez-Martin, E.4    Mena, M.A.5
  • 4
    • 1942501585 scopus 로고    scopus 로고
    • 12/15-lipoxygenase is increased in Alzheimer's disease: Possible involvement in brain oxidative stress
    • D. Pratico, V. Zhukareva, Y. Yao, K. Uryu, C.D. Funk, and J.A. Lawson 12/15-lipoxygenase is increased in Alzheimer's disease: possible involvement in brain oxidative stress Am J Pathol 164 2004 1655 1662
    • (2004) Am J Pathol , vol.164 , pp. 1655-1662
    • Pratico, D.1    Zhukareva, V.2    Yao, Y.3    Uryu, K.4    Funk, C.D.5    Lawson, J.A.6
  • 5
    • 49449090767 scopus 로고    scopus 로고
    • Biochemistry and physiology of mammalian secreted phospholipases A2
    • G. Lambeau, and M.H. Gelb Biochemistry and physiology of mammalian secreted phospholipases A2 Ann Rev Biochem 77 2008 495 520
    • (2008) Ann Rev Biochem , vol.77 , pp. 495-520
    • Lambeau, G.1    Gelb, M.H.2
  • 6
    • 4444350561 scopus 로고    scopus 로고
    • Lipid inflammatory mediators in diabetic vascular disease
    • R. Natarajan, and J.L. Nadler Lipid inflammatory mediators in diabetic vascular disease Arterioscler Thromb Vasc Biol 24 2004 1542 1548
    • (2004) Arterioscler Thromb Vasc Biol , vol.24 , pp. 1542-1548
    • Natarajan, R.1    Nadler, J.L.2
  • 7
    • 0033588022 scopus 로고    scopus 로고
    • Lipoxygenases: Occurrence, functions, catalysis, and acquisition of substrate
    • A.R. Brash Lipoxygenases: occurrence, functions, catalysis, and acquisition of substrate J Biol Chem 274 1999 23679 23682
    • (1999) J Biol Chem , vol.274 , pp. 23679-23682
    • Brash, A.R.1
  • 8
    • 0035976575 scopus 로고    scopus 로고
    • Prostaglandins and leukotrienes: Advances in eicosanoid biology
    • C.D. Funk Prostaglandins and leukotrienes: advances in eicosanoid biology Science 294 2001 1871 1875
    • (2001) Science , vol.294 , pp. 1871-1875
    • Funk, C.D.1
  • 9
    • 0027166718 scopus 로고
    • Structure-function properties of human platelet 12-lipoxygenase: Chimeric enzyme and in vitro mutagenesis studies
    • X.S. Chen, and C.D. Funk Structure-function properties of human platelet 12-lipoxygenase: chimeric enzyme and in vitro mutagenesis studies Faseb J 7 1993 694 701
    • (1993) Faseb J , vol.7 , pp. 694-701
    • Chen, X.S.1    Funk, C.D.2
  • 10
    • 0036669583 scopus 로고    scopus 로고
    • Mammalian arachidonate 15-lipoxygenases structure, function, and biological implications
    • H. Kuhn, M. Walther, and R.J. Kuban Mammalian arachidonate 15-lipoxygenases structure, function, and biological implications Prostaglandins Other Lipid Mediat 68-69 2002 263 290
    • (2002) Prostaglandins Other Lipid Mediat , vol.6869 , pp. 263-290
    • Kuhn, H.1    Walther, M.2    Kuban, R.J.3
  • 11
    • 0028216578 scopus 로고
    • CDNA cloning, expression, mutagenesis of C-terminal isoleucine, genomic structure, and chromosomal localizations of murine 12-lipoxygenases
    • X.S. Chen, U. Kurre, N.A. Jenkins, N.G. Copeland, and C.D. Funk CDNA cloning, expression, mutagenesis of C-terminal isoleucine, genomic structure, and chromosomal localizations of murine 12-lipoxygenases J Biol Chem 269 1994 13979 13987
    • (1994) J Biol Chem , vol.269 , pp. 13979-13987
    • Chen, X.S.1    Kurre, U.2    Jenkins, N.A.3    Copeland, N.G.4    Funk, C.D.5
  • 12
    • 0032557633 scopus 로고    scopus 로고
    • Simultaneous expression of leukocyte-type 12-lipoxygenase and reticulocyte-type 15-lipoxygenase in rabbits
    • M. Berger, K. Schwarz, H. Thiele, I. Reimann, A. Huth, and S. Borngraber Simultaneous expression of leukocyte-type 12-lipoxygenase and reticulocyte-type 15-lipoxygenase in rabbits J Mol Biol 278 1998 935 948
    • (1998) J Mol Biol , vol.278 , pp. 935-948
    • Berger, M.1    Schwarz, K.2    Thiele, H.3    Reimann, I.4    Huth, A.5    Borngraber, S.6
  • 13
    • 37349120736 scopus 로고    scopus 로고
    • Arachidonic acid metabolites in the cardiovascular system: The role of lipoxygenase isoforms in atherogenesis with particular emphasis on vascular remodeling
    • H. Kuhn, P. Chaitidis, J. Roffeis, and M. Walther Arachidonic acid metabolites in the cardiovascular system: the role of lipoxygenase isoforms in atherogenesis with particular emphasis on vascular remodeling J Cardiovasc Pharmacol 50 2007 609 620
    • (2007) J Cardiovasc Pharmacol , vol.50 , pp. 609-620
    • Kuhn, H.1    Chaitidis, P.2    Roffeis, J.3    Walther, M.4
  • 14
    • 0035417925 scopus 로고    scopus 로고
    • Lipoxygenase modulation to reverse carcinogenesis
    • I. Shureiqi, and S.M. Lippman Lipoxygenase modulation to reverse carcinogenesis Cancer Res 61 2001 6307 6312
    • (2001) Cancer Res , vol.61 , pp. 6307-6312
    • Shureiqi, I.1    Lippman, S.M.2
  • 15
    • 0029970957 scopus 로고    scopus 로고
    • Lipoxygenase metabolites induced expression of adhesion molecules and transendothelial migration of monocyte-like HL-60 cells is linked to protein kinase C activation
    • C. Sultana, Y. Shen, V. Rattan, and V.K. Kalra Lipoxygenase metabolites induced expression of adhesion molecules and transendothelial migration of monocyte-like HL-60 cells is linked to protein kinase C activation J Cell Physiol 167 1996 477 487
    • (1996) J Cell Physiol , vol.167 , pp. 477-487
    • Sultana, C.1    Shen, Y.2    Rattan, V.3    Kalra, V.K.4
  • 16
    • 0035572857 scopus 로고    scopus 로고
    • Signaling mechanisms of nuclear factor-kappab-mediated activation of inflammatory genes by 13-hydroperoxyoctadecadienoic acid in cultured vascular smooth muscle cells
    • R. Natarajan, M.A. Reddy, K.U. Malik, S. Fatima, and B.V. Khan Signaling mechanisms of nuclear factor-kappab-mediated activation of inflammatory genes by 13-hydroperoxyoctadecadienoic acid in cultured vascular smooth muscle cells Arterioscler Thromb Vasc Biol 21 2001 1408 1413
    • (2001) Arterioscler Thromb Vasc Biol , vol.21 , pp. 1408-1413
    • Natarajan, R.1    Reddy, M.A.2    Malik, K.U.3    Fatima, S.4    Khan, B.V.5
  • 17
    • 0037155879 scopus 로고    scopus 로고
    • The oxidized lipid and lipoxygenase product 12(S)-hydroxyeicosatetraenoic acid induces hypertrophy and fibronectin transcription in vascular smooth muscle cells via p38 MAPK and cAMP response element-binding protein activation. Mediation of angiotensin II effects
    • M.A. Reddy, P.R. Thimmalapura, L. Lanting, J.L. Nadler, S. Fatima, and R. Natarajan The oxidized lipid and lipoxygenase product 12(S)- hydroxyeicosatetraenoic acid induces hypertrophy and fibronectin transcription in vascular smooth muscle cells via p38 MAPK and cAMP response element-binding protein activation. Mediation of angiotensin II effects J Biol Chem 277 2002 9920 9928
    • (2002) J Biol Chem , vol.277 , pp. 9920-9928
    • Reddy, M.A.1    Thimmalapura, P.R.2    Lanting, L.3    Nadler, J.L.4    Fatima, S.5    Natarajan, R.6
  • 18
    • 70350127334 scopus 로고    scopus 로고
    • Lipoxins: Resolutionary road
    • P. Maderna, and C. Godson Lipoxins: resolutionary road Br J Pharmacol 158 2009 947 959
    • (2009) Br J Pharmacol , vol.158 , pp. 947-959
    • Maderna, P.1    Godson, C.2
  • 19
    • 77952105540 scopus 로고    scopus 로고
    • Resolvins and protectins: Natural pharmacophores for resolution biology
    • B.D. Levy Resolvins and protectins: natural pharmacophores for resolution biology Prostaglandins Leukot Essent Fatty Acids 82 2010 327 332
    • (2010) Prostaglandins Leukot Essent Fatty Acids , vol.82 , pp. 327-332
    • Levy, B.D.1
  • 21
    • 33846001661 scopus 로고    scopus 로고
    • Protectin D1 is generated in asthma and dampens airway inflammation and hyperresponsiveness
    • B.D. Levy, P. Kohli, K. Gotlinger, O. Haworth, S. Hong, and S. Kazani Protectin D1 is generated in asthma and dampens airway inflammation and hyperresponsiveness J Immunol 178 2007 496 502
    • (2007) J Immunol , vol.178 , pp. 496-502
    • Levy, B.D.1    Kohli, P.2    Gotlinger, K.3    Haworth, O.4    Hong, S.5    Kazani, S.6
  • 23
    • 0031975571 scopus 로고    scopus 로고
    • Membrane translocation of 15-lipoxygenase in hematopoietic cells is calcium-dependent and activates the oxygenase activity of the enzyme
    • R. Brinckmann, K. Schnurr, D. Heydeck, T. Rosenbach, G. Kolde, and H. Kuhn Membrane translocation of 15-lipoxygenase in hematopoietic cells is calcium-dependent and activates the oxygenase activity of the enzyme Blood 91 1998 64 74
    • (1998) Blood , vol.91 , pp. 64-74
    • Brinckmann, R.1    Schnurr, K.2    Heydeck, D.3    Rosenbach, T.4    Kolde, G.5    Kuhn, H.6
  • 24
    • 33744550207 scopus 로고    scopus 로고
    • Inflammation and immune regulation by 12/15-lipoxygenases
    • H. Kuhn, and V.B. O'Donnell Inflammation and immune regulation by 12/15-lipoxygenases Prog Lipid Res 45 2006 334 356
    • (2006) Prog Lipid Res , vol.45 , pp. 334-356
    • Kuhn, H.1    O'Donnell, V.B.2
  • 26
    • 77951214211 scopus 로고    scopus 로고
    • Phospholipid-esterified eicosanoids are generated in agonist-activated human platelets and enhance tissue factor-dependent thrombin generation
    • C.P. Thomas, L.T. Morgan, B.H. Maskrey, R.C. Murphy, H. Kuhn, and S.L. Hazen Phospholipid-esterified eicosanoids are generated in agonist-activated human platelets and enhance tissue factor-dependent thrombin generation J Biol Chem 285 2010 6891 6903
    • (2010) J Biol Chem , vol.285 , pp. 6891-6903
    • Thomas, C.P.1    Morgan, L.T.2    Maskrey, B.H.3    Murphy, R.C.4    Kuhn, H.5    Hazen, S.L.6
  • 27
    • 69249139081 scopus 로고    scopus 로고
    • Phosphatidylethanolamine-esterified eicosanoids in the mouse: Tissue localization and inflammation-dependent formation in Th-2 disease
    • A.H. Morgan, V. Dioszeghy, B.H. Maskrey, C.P. Thomas, S.R. Clark, and S.A. Mathie Phosphatidylethanolamine-esterified eicosanoids in the mouse: tissue localization and inflammation-dependent formation in Th-2 disease J Biol Chem 284 2009 21185 21191
    • (2009) J Biol Chem , vol.284 , pp. 21185-21191
    • Morgan, A.H.1    Dioszeghy, V.2    Maskrey, B.H.3    Thomas, C.P.4    Clark, S.R.5    Mathie, S.A.6
  • 28
    • 33144489526 scopus 로고    scopus 로고
    • Novel human lipoxygenase inhibitors discovered using virtual screening with homology models
    • V. Kenyon, I. Chorny, W.J. Carvajal, T.R. Holman, and M.P. Jacobson Novel human lipoxygenase inhibitors discovered using virtual screening with homology models J Med Chem 49 2006 1356 1363
    • (2006) J Med Chem , vol.49 , pp. 1356-1363
    • Kenyon, V.1    Chorny, I.2    Carvajal, W.J.3    Holman, T.R.4    Jacobson, M.P.5
  • 29
    • 59849119874 scopus 로고    scopus 로고
    • Eicosanoids: Generation and detection in mammalian cells
    • V.B. O'Donnell, B. Maskrey, and G.W. Taylor Eicosanoids: generation and detection in mammalian cells Methods Mol Biol 462 2009 5 23
    • (2009) Methods Mol Biol , vol.462 , pp. 5-23
    • O'Donnell, V.B.1    Maskrey, B.2    Taylor, G.W.3
  • 31
    • 16844383761 scopus 로고    scopus 로고
    • Activation of 12-lipoxygenase in proinflammatory cytokine-mediated beta cell toxicity
    • M. Chen, Z.D. Yang, K.M. Smith, J.D. Carter, and J.L. Nadler Activation of 12-lipoxygenase in proinflammatory cytokine-mediated beta cell toxicity Diabetologia 48 2005 486 495
    • (2005) Diabetologia , vol.48 , pp. 486-495
    • Chen, M.1    Yang, Z.D.2    Smith, K.M.3    Carter, J.D.4    Nadler, J.L.5
  • 32
    • 0037192853 scopus 로고    scopus 로고
    • Genetic regulation of metabolic pathways in beta-cells disrupted by hyperglycemia
    • D.R. Laybutt, A. Sharma, D.C. Sgroi, J. Gaudet, S. Bonner-Weir, and G.C. Weir Genetic regulation of metabolic pathways in beta-cells disrupted by hyperglycemia J Biol Chem 277 2002 10912 10921
    • (2002) J Biol Chem , vol.277 , pp. 10912-10921
    • Laybutt, D.R.1    Sharma, A.2    Sgroi, D.C.3    Gaudet, J.4    Bonner-Weir, S.5    Weir, G.C.6
  • 33
    • 0027233841 scopus 로고
    • Elevated glucose and angiotensin II increase 12-lipoxygenase activity and expression in porcine aortic smooth muscle cells
    • R. Natarajan, J.L. Gu, J. Rossi, N. Gonzales, L. Lanting, and L. Xu Elevated glucose and angiotensin II increase 12-lipoxygenase activity and expression in porcine aortic smooth muscle cells Proc Natl Acad Sci USA 90 1993 4947 4951
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 4947-4951
    • Natarajan, R.1    Gu, J.L.2    Rossi, J.3    Gonzales, N.4    Lanting, L.5    Xu, L.6
  • 34
    • 0028874383 scopus 로고
    • Evolution of beta-cell dysfunction in the male Zucker diabetic fatty rat
    • Y. Tokuyama, J. Sturis, A.M. DePaoli, J. Takeda, M. Stoffel, and J. Tang Evolution of beta-cell dysfunction in the male Zucker diabetic fatty rat Diabetes 44 1995 1447 1457
    • (1995) Diabetes , vol.44 , pp. 1447-1457
    • Tokuyama, Y.1    Sturis, J.2    Depaoli, A.M.3    Takeda, J.4    Stoffel, M.5    Tang, J.6
  • 36
    • 70349639659 scopus 로고    scopus 로고
    • 12/15-lipoxygenase is required for the early onset of high fat diet-induced adipose tissue inflammation and insulin resistance in mice
    • D.D. Sears, P.D. Miles, J. Chapman, J.M. Ofrecio, F. Almazan, and D. Thapar 12/15-lipoxygenase is required for the early onset of high fat diet-induced adipose tissue inflammation and insulin resistance in mice PLoS One 4 2009 e7250
    • (2009) PLoS One , vol.4 , pp. 7250
    • Sears, D.D.1    Miles, P.D.2    Chapman, J.3    Ofrecio, J.M.4    Almazan, F.5    Thapar, D.6
  • 37
    • 0032723345 scopus 로고    scopus 로고
    • Resistance to type 1 diabetes induction in 12-lipoxygenase knockout mice
    • D. Bleich, S. Chen, B. Zipser, D. Sun, C.D. Funk, and J.L. Nadler Resistance to type 1 diabetes induction in 12-lipoxygenase knockout mice J Clin Invest 103 1999 1431 1436
    • (1999) J Clin Invest , vol.103 , pp. 1431-1436
    • Bleich, D.1    Chen, S.2    Zipser, B.3    Sun, D.4    Funk, C.D.5    Nadler, J.L.6
  • 38
    • 38449098081 scopus 로고    scopus 로고
    • Nonobese diabetic (NOD) mice congenic for a targeted deletion of 12/15-lipoxygenase are protected from autoimmune diabetes
    • M. McDuffie, N.A. Maybee, S.R. Keller, B.K. Stevens, J.C. Garmey, and M.A. Morris Nonobese diabetic (NOD) mice congenic for a targeted deletion of 12/15-lipoxygenase are protected from autoimmune diabetes Diabetes 57 2008 199 208
    • (2008) Diabetes , vol.57 , pp. 199-208
    • McDuffie, M.1    Maybee, N.A.2    Keller, S.R.3    Stevens, B.K.4    Garmey, J.C.5    Morris, M.A.6
  • 39
    • 0036141930 scopus 로고    scopus 로고
    • Lipoxin-mediated inhibition of IL-12 production by DCs: A mechanism for regulation of microbial immunity
    • J. Aliberti, S. Hieny, C. Reis e Sousa, C.N. Serhan, and A. Sher Lipoxin-mediated inhibition of IL-12 production by DCs: a mechanism for regulation of microbial immunity Nat Immunol 3 2002 76 82
    • (2002) Nat Immunol , vol.3 , pp. 76-82
    • Aliberti, J.1    Hieny, S.2    Reis Sousa e, C.3    Serhan, C.N.4    Sher, A.5
  • 40
    • 0037144594 scopus 로고    scopus 로고
    • Selective interleukin-12 synthesis defect in 12/15-lipoxygenase-deficient macrophages associated with reduced atherosclerosis in a mouse model of familial hypercholesterolemia
    • L. Zhao, C.A. Cuff, E. Moss, U. Wille, T. Cyrus, and E.A. Klein Selective interleukin-12 synthesis defect in 12/15-lipoxygenase-deficient macrophages associated with reduced atherosclerosis in a mouse model of familial hypercholesterolemia J Biol Chem 277 2002 35350 35356
    • (2002) J Biol Chem , vol.277 , pp. 35350-35356
    • Zhao, L.1    Cuff, C.A.2    Moss, E.3    Wille, U.4    Cyrus, T.5    Klein, E.A.6
  • 41
    • 29644436198 scopus 로고    scopus 로고
    • Cellular and molecular mechanisms of the selective regulation of IL-12 production by 12/15-lipoxygenase
    • M.K. Middleton, T. Rubinstein, and E. Pure Cellular and molecular mechanisms of the selective regulation of IL-12 production by 12/15-lipoxygenase J Immunol 176 2006 265 274
    • (2006) J Immunol , vol.176 , pp. 265-274
    • Middleton, M.K.1    Rubinstein, T.2    Pure, E.3
  • 42
    • 72449156038 scopus 로고    scopus 로고
    • 12/15-lipoxygenase-dependent myeloid production of interleukin-12 is essential for resistance to chronic toxoplasmosis
    • M.K. Middleton, A.M. Zukas, T. Rubinstein, M. Kinder, E.H. Wilson, and P. Zhu 12/15-lipoxygenase-dependent myeloid production of interleukin-12 is essential for resistance to chronic toxoplasmosis Infect Immun 77 2009 5690 5700
    • (2009) Infect Immun , vol.77 , pp. 5690-5700
    • Middleton, M.K.1    Zukas, A.M.2    Rubinstein, T.3    Kinder, M.4    Wilson, E.H.5    Zhu, P.6
  • 43
    • 0028972876 scopus 로고
    • Interleukin-1 beta regulates the expression of a leukocyte type of 12-lipoxygenase in rat islets and RIN m5F cells
    • D. Bleich, S. Chen, J.L. Gu, L. Thomas, S. Scott, and N. Gonzales Interleukin-1 beta regulates the expression of a leukocyte type of 12-lipoxygenase in rat islets and RIN m5F cells Endocrinology 136 1995 5736 5744
    • (1995) Endocrinology , vol.136 , pp. 5736-5744
    • Bleich, D.1    Chen, S.2    Gu, J.L.3    Thomas, L.4    Scott, S.5    Gonzales, N.6
  • 44
    • 0031566151 scopus 로고    scopus 로고
    • The stress-activated c-Jun protein kinase (JNK) is stimulated by lipoxygenase pathway product 12-HETE in RIN m5F cells
    • D. Bleich, S. Chen, Y. Wen, and J.L. Nadler The stress-activated c-Jun protein kinase (JNK) is stimulated by lipoxygenase pathway product 12-HETE in RIN m5F cells Biochem Biophys Res Commun 230 1997 448 451
    • (1997) Biochem Biophys Res Commun , vol.230 , pp. 448-451
    • Bleich, D.1    Chen, S.2    Wen, Y.3    Nadler, J.L.4
  • 45
    • 0041664876 scopus 로고    scopus 로고
    • Evidence that increased 12-lipoxygenase expression impairs pancreatic beta cell function and viability
    • K.M. Prasad, P.R. Thimmalapura, E.A. Woode, and J.L. Nadler Evidence that increased 12-lipoxygenase expression impairs pancreatic beta cell function and viability Biochem Biophys Res Commun 308 2003 427 432
    • (2003) Biochem Biophys Res Commun , vol.308 , pp. 427-432
    • Prasad, K.M.1    Thimmalapura, P.R.2    Woode, E.A.3    Nadler, J.L.4
  • 46
    • 36048930552 scopus 로고    scopus 로고
    • 12(S)-hydroperoxyeicosatetraenoic acid (12-HETE) increases mitochondrial nitric oxide by increasing intramitochondrial calcium
    • R.R. Nazarewicz, W.J. Zenebe, A. Parihar, M.S. Parihar, M. Vaccaro, and C. Rink 12(S)-hydroperoxyeicosatetraenoic acid (12-HETE) increases mitochondrial nitric oxide by increasing intramitochondrial calcium Arch Biochem Biophys 468 2007 114 120
    • (2007) Arch Biochem Biophys , vol.468 , pp. 114-120
    • Nazarewicz, R.R.1    Zenebe, W.J.2    Parihar, A.3    Parihar, M.S.4    Vaccaro, M.5    Rink, C.6
  • 47
    • 0038448178 scopus 로고    scopus 로고
    • 5-Lipoxygenase-derived leukotrienes: Mediators also of atherosclerotic inflammation
    • O. Radmark 5-Lipoxygenase-derived leukotrienes: mediators also of atherosclerotic inflammation Arterioscler Thromb Vasc Biol 23 2003 1140 1142
    • (2003) Arterioscler Thromb Vasc Biol , vol.23 , pp. 1140-1142
    • Radmark, O.1
  • 48
    • 33847034426 scopus 로고    scopus 로고
    • The role of arachidonic acid and its metabolites in insulin secretion from human islets of langerhans
    • S.J. Persaud, D. Muller, V.D. Belin, I. Kitsou-Mylona, H. Asare-Anane, and A. Papadimitriou The role of arachidonic acid and its metabolites in insulin secretion from human islets of langerhans Diabetes 56 2007 197 203
    • (2007) Diabetes , vol.56 , pp. 197-203
    • Persaud, S.J.1    Muller, D.2    Belin, V.D.3    Kitsou-Mylona, I.4    Asare-Anane, H.5    Papadimitriou, A.6
  • 49
    • 0036716833 scopus 로고    scopus 로고
    • Induction of cyclooxygenase-2 gene in pancreatic beta-cells by 12-lipoxygenase pathway product 12-hydroxyeicosatetraenoic acid
    • X. Han, S. Chen, Y. Sun, J.L. Nadler, and D. Bleich Induction of cyclooxygenase-2 gene in pancreatic beta-cells by 12-lipoxygenase pathway product 12-hydroxyeicosatetraenoic acid Mol Endocrinol 16 2002 2145 2154
    • (2002) Mol Endocrinol , vol.16 , pp. 2145-2154
    • Han, X.1    Chen, S.2    Sun, Y.3    Nadler, J.L.4    Bleich, D.5
  • 50
    • 0037449723 scopus 로고    scopus 로고
    • Minimally modified LDL binds to CD14, induces macrophage spreading via TLR4/MD-2, and inhibits phagocytosis of apoptotic cells
    • Y.I. Miller, S. Viriyakosol, C.J. Binder, J.R. Feramisco, T.N. Kirkland, and J.L. Witztum Minimally modified LDL binds to CD14, induces macrophage spreading via TLR4/MD-2, and inhibits phagocytosis of apoptotic cells J Biol Chem 278 2003 1561 1568
    • (2003) J Biol Chem , vol.278 , pp. 1561-1568
    • Miller, Y.I.1    Viriyakosol, S.2    Binder, C.J.3    Feramisco, J.R.4    Kirkland, T.N.5    Witztum, J.L.6
  • 51
    • 20144385204 scopus 로고    scopus 로고
    • Toll-like receptor 4-dependent and -independent cytokine secretion induced by minimally oxidized low-density lipoprotein in macrophages
    • Y.I. Miller, S. Viriyakosol, D.S. Worrall, A. Boullier, S. Butler, and J.L. Witztum Toll-like receptor 4-dependent and -independent cytokine secretion induced by minimally oxidized low-density lipoprotein in macrophages Arterioscler Thromb Vasc Biol 25 2005 1213 1219
    • (2005) Arterioscler Thromb Vasc Biol , vol.25 , pp. 1213-1219
    • Miller, Y.I.1    Viriyakosol, S.2    Worrall, D.S.3    Boullier, A.4    Butler, S.5    Witztum, J.L.6
  • 52
    • 0020570204 scopus 로고
    • Lipoxygenase pathway in islet endocrine cells. Oxidative metabolism of arachidonic acid promotes insulin release
    • S. Metz, M. VanRollins, R. Strife, W. Fujimoto, and R.P. Robertson Lipoxygenase pathway in islet endocrine cells. Oxidative metabolism of arachidonic acid promotes insulin release J Clin Invest 71 1983 1191 1205
    • (1983) J Clin Invest , vol.71 , pp. 1191-1205
    • Metz, S.1    Vanrollins, M.2    Strife, R.3    Fujimoto, W.4    Robertson, R.P.5
  • 53
    • 0021921015 scopus 로고
    • Glucose increases the synthesis of lipoxygenase-mediated metabolites of arachidonic acid in intact rat islets
    • S.A. Metz Glucose increases the synthesis of lipoxygenase-mediated metabolites of arachidonic acid in intact rat islets Proc Natl Acad Sci USA 82 1985 198 202
    • (1985) Proc Natl Acad Sci USA , vol.82 , pp. 198-202
    • Metz, S.A.1
  • 54
    • 0021907945 scopus 로고
    • Arachidonic acid metabolism in isolated pancreatic islets. III. Effects of exogenous lipoxygenase products and inhibitors on insulin secretion
    • J. Turk, J.R. Colca, and M.L. McDaniel Arachidonic acid metabolism in isolated pancreatic islets. III. Effects of exogenous lipoxygenase products and inhibitors on insulin secretion Biochim Biophys Acta 834 1985 23 36
    • (1985) Biochim Biophys Acta , vol.834 , pp. 23-36
    • Turk, J.1    Colca, J.R.2    McDaniel, M.L.3
  • 55
    • 0026454365 scopus 로고
    • Selective expression of an arachidonate 12-lipoxygenase by pancreatic islet beta-cells
    • V.R. Shannon, S. Ramanadham, J. Turk, and M.J. Holtzman Selective expression of an arachidonate 12-lipoxygenase by pancreatic islet beta-cells Am J Physiol 263 1992 E828 E836
    • (1992) Am J Physiol , vol.263
    • Shannon, V.R.1    Ramanadham, S.2    Turk, J.3    Holtzman, M.J.4
  • 56
    • 0033808074 scopus 로고    scopus 로고
    • Expression of arachidonate 12-lipoxygenase in rat tissues: A possible role in glucagon secretion
    • H. Kawajiri, D. Zhuang, N. Qiao, T. Yoshimoto, M. Yamamoto, and S. Iseki Expression of arachidonate 12-lipoxygenase in rat tissues: a possible role in glucagon secretion J Histochem Cytochem 48 2000 1411 1419
    • (2000) J Histochem Cytochem , vol.48 , pp. 1411-1419
    • Kawajiri, H.1    Zhuang, D.2    Qiao, N.3    Yoshimoto, T.4    Yamamoto, M.5    Iseki, S.6
  • 57
    • 34547399482 scopus 로고    scopus 로고
    • High-fat diet induced neuropathy of pre-diabetes and obesity: Effects of "healthy" diet and aldose reductase inhibition
    • I.G. Obrosova, O. Ilnytska, V.V. Lyzogubov, I.A. Pavlov, N. Mashtalir, and J.L. Nadler High-fat diet induced neuropathy of pre-diabetes and obesity: effects of "healthy" diet and aldose reductase inhibition Diabetes 56 2007 2598 2608
    • (2007) Diabetes , vol.56 , pp. 2598-2608
    • Obrosova, I.G.1    Ilnytska, O.2    Lyzogubov, V.V.3    Pavlov, I.A.4    Mashtalir, N.5    Nadler, J.L.6
  • 58
    • 77952501888 scopus 로고    scopus 로고
    • High-fat diet-induced neuropathy of prediabetes and obesity: Effect of PMI-5011, an ethanolic extract of Artemisia dracunculus L
    • P. Watcho, R. Stavniichuk, D.M. Ribnicky, I. Raskin, and I.G. Obrosova High-fat diet-induced neuropathy of prediabetes and obesity: effect of PMI-5011, an ethanolic extract of Artemisia dracunculus L. Mediators Inflamm 2010 2010 268547
    • (2010) Mediators Inflamm , vol.2010 , pp. 268547
    • Watcho, P.1    Stavniichuk, R.2    Ribnicky, D.M.3    Raskin, I.4    Obrosova, I.G.5
  • 60
    • 0031014333 scopus 로고    scopus 로고
    • Detection of eicosanoids in epiretinal membranes of patients suffering from proliferative vitreoretinal diseases
    • A.J. Augustin, F.H. Grus, F. Koch, and M. Spitznas Detection of eicosanoids in epiretinal membranes of patients suffering from proliferative vitreoretinal diseases Br J Ophthalmol 81 1997 58 60
    • (1997) Br J Ophthalmol , vol.81 , pp. 58-60
    • Augustin, A.J.1    Grus, F.H.2    Koch, F.3    Spitznas, M.4
  • 61
    • 77954264059 scopus 로고    scopus 로고
    • Profile of lipid and protein autacoids in diabetic vitreous correlates with the progression of diabetic retinopathy
    • M.L. Schwartzman, P. Iserovich, K. Gotlinger, L. Bellner, M.W. Dunn, and M. Sartore Profile of lipid and protein autacoids in diabetic vitreous correlates with the progression of diabetic retinopathy Diabetes 59 2010 1780 1788
    • (2010) Diabetes , vol.59 , pp. 1780-1788
    • Schwartzman, M.L.1    Iserovich, P.2    Gotlinger, K.3    Bellner, L.4    Dunn, M.W.5    Sartore, M.6
  • 62
    • 48449097142 scopus 로고    scopus 로고
    • 5-Lipoxygenase, but not 12/15-lipoxygenase, contributes to degeneration of retinal capillaries in a mouse model of diabetic retinopathy
    • R.A. Gubitosi-Klug, R. Talahalli, Y. Du, J.L. Nadler, and T.S. Kern 5-Lipoxygenase, but not 12/15-lipoxygenase, contributes to degeneration of retinal capillaries in a mouse model of diabetic retinopathy Diabetes 57 2008 1387 1393
    • (2008) Diabetes , vol.57 , pp. 1387-1393
    • Gubitosi-Klug, R.A.1    Talahalli, R.2    Du, Y.3    Nadler, J.L.4    Kern, T.S.5
  • 63
    • 0242468739 scopus 로고    scopus 로고
    • Adipocyte differentiation of 3T3-L1 preadipocytes is dependent on lipoxygenase activity during the initial stages of the differentiation process
    • L. Madsen, R.K. Petersen, M.B. Sorensen, C. Jorgensen, P. Hallenborg, and L. Pridal Adipocyte differentiation of 3T3-L1 preadipocytes is dependent on lipoxygenase activity during the initial stages of the differentiation process Biochem J 375 2003 539 549
    • (2003) Biochem J , vol.375 , pp. 539-549
    • Madsen, L.1    Petersen, R.K.2    Sorensen, M.B.3    Jorgensen, C.4    Hallenborg, P.5    Pridal, L.6
  • 64
    • 0016178461 scopus 로고
    • An established pre-adipose cell line and its differentiation in culture
    • H. Green, and M. Meuth An established pre-adipose cell line and its differentiation in culture Cell 3 1974 127 133
    • (1974) Cell , vol.3 , pp. 127-133
    • Green, H.1    Meuth, M.2
  • 65
    • 0019203221 scopus 로고
    • Search for the adipocyte precursor cell and factors that promote its differentiation
    • G.J. Hausman, D.R. Campion, and R.J. Martin Search for the adipocyte precursor cell and factors that promote its differentiation J Lipid Res 21 1980 657 670
    • (1980) J Lipid Res , vol.21 , pp. 657-670
    • Hausman, G.J.1    Campion, D.R.2    Martin, R.J.3
  • 66
    • 0033213637 scopus 로고    scopus 로고
    • PPAR gamma is required for placental, cardiac, and adipose tissue development
    • Y. Barak, M.C. Nelson, E.S. Ong, Y.Z. Jones, P. Ruiz-Lozano, and K.R. Chien PPAR gamma is required for placental, cardiac, and adipose tissue development Mol Cell 4 1999 585 595
    • (1999) Mol Cell , vol.4 , pp. 585-595
    • Barak, Y.1    Nelson, M.C.2    Ong, E.S.3    Jones, Y.Z.4    Ruiz-Lozano, P.5    Chien, K.R.6
  • 67
    • 0033212964 scopus 로고    scopus 로고
    • PPAR gamma mediates high-fat diet-induced adipocyte hypertrophy and insulin resistance
    • N. Kubota, Y. Terauchi, H. Miki, H. Tamemoto, T. Yamauchi, and K. Komeda PPAR gamma mediates high-fat diet-induced adipocyte hypertrophy and insulin resistance Mol Cell 4 1999 597 609
    • (1999) Mol Cell , vol.4 , pp. 597-609
    • Kubota, N.1    Terauchi, Y.2    Miki, H.3    Tamemoto, H.4    Yamauchi, T.5    Komeda, K.6
  • 68
    • 0033213631 scopus 로고    scopus 로고
    • PPAR gamma is required for the differentiation of adipose tissue in vivo and in vitro
    • E.D. Rosen, P. Sarraf, A.E. Troy, G. Bradwin, K. Moore, and D.S. Milstone PPAR gamma is required for the differentiation of adipose tissue in vivo and in vitro Mol Cell 4 1999 611 617
    • (1999) Mol Cell , vol.4 , pp. 611-617
    • Rosen, E.D.1    Sarraf, P.2    Troy, A.E.3    Bradwin, G.4    Moore, K.5    Milstone, D.S.6
  • 69
    • 0028802627 scopus 로고
    • Differential activation of peroxisome proliferator-activated receptors by eicosanoids
    • K. Yu, W. Bayona, C.B. Kallen, H.P. Harding, C.P. Ravera, and G. McMahon Differential activation of peroxisome proliferator-activated receptors by eicosanoids J Biol Chem 270 1995 23975 23983
    • (1995) J Biol Chem , vol.270 , pp. 23975-23983
    • Yu, K.1    Bayona, W.2    Kallen, C.B.3    Harding, H.P.4    Ravera, C.P.5    McMahon, G.6
  • 70
    • 0032540325 scopus 로고    scopus 로고
    • Oxidized LDL regulates macrophage gene expression through ligand activation of PPARgamma
    • L. Nagy, P. Tontonoz, J.G. Alvarez, H. Chen, and R.M. Evans Oxidized LDL regulates macrophage gene expression through ligand activation of PPARgamma Cell 93 1998 229 240
    • (1998) Cell , vol.93 , pp. 229-240
    • Nagy, L.1    Tontonoz, P.2    Alvarez, J.G.3    Chen, H.4    Evans, R.M.5
  • 71
    • 0033595261 scopus 로고    scopus 로고
    • Interleukin-4-dependent production of PPAR-gamma ligands in macrophages by 12/15-lipoxygenase
    • J.T. Huang, J.S. Welch, M. Ricote, C.J. Binder, T.M. Willson, and C. Kelly Interleukin-4-dependent production of PPAR-gamma ligands in macrophages by 12/15-lipoxygenase Nature 400 1999 378 382
    • (1999) Nature , vol.400 , pp. 378-382
    • Huang, J.T.1    Welch, J.S.2    Ricote, M.3    Binder, C.J.4    Willson, T.M.5    Kelly, C.6
  • 72
    • 0035863307 scopus 로고    scopus 로고
    • 15S-Hydroxyeicosatetraenoic acid activates peroxisome proliferator-activated receptor gamma and inhibits proliferation in PC3 prostate carcinoma cells
    • S.B. Shappell, R.A. Gupta, S. Manning, R. Whitehead, W.E. Boeglin, and C. Schneider 15S-Hydroxyeicosatetraenoic acid activates peroxisome proliferator-activated receptor gamma and inhibits proliferation in PC3 prostate carcinoma cells Cancer Res 61 2001 497 503
    • (2001) Cancer Res , vol.61 , pp. 497-503
    • Shappell, S.B.1    Gupta, R.A.2    Manning, S.3    Whitehead, R.4    Boeglin, W.E.5    Schneider, C.6
  • 73
    • 0037189536 scopus 로고    scopus 로고
    • 15-Lipoxygenase metabolism of 2-arachidonylglycerol. Generation of a peroxisome proliferator-activated receptor alpha agonist
    • K.R. Kozak, R.A. Gupta, J.S. Moody, C. Ji, W.E. Boeglin, and R.N. DuBois 15-Lipoxygenase metabolism of 2-arachidonylglycerol. Generation of a peroxisome proliferator-activated receptor alpha agonist J Biol Chem 277 2002 23278 23286
    • (2002) J Biol Chem , vol.277 , pp. 23278-23286
    • Kozak, K.R.1    Gupta, R.A.2    Moody, J.S.3    Ji, C.4    Boeglin, W.E.5    Dubois, R.N.6
  • 74
    • 0035937793 scopus 로고    scopus 로고
    • Arachidonic acid stimulates glucose uptake in 3T3-L1 adipocytes by increasing GLUT1 and GLUT4 levels at the plasma membrane. Evidence for involvement of lipoxygenase metabolites and peroxisome proliferator-activated receptor gamma
    • C. Nugent, J.B. Prins, J.P. Whitehead, J.M. Wentworth, V.K. Chatterjee, and S. O'Rahilly Arachidonic acid stimulates glucose uptake in 3T3-L1 adipocytes by increasing GLUT1 and GLUT4 levels at the plasma membrane. Evidence for involvement of lipoxygenase metabolites and peroxisome proliferator-activated receptor gamma J Biol Chem 276 2001 9149 9157
    • (2001) J Biol Chem , vol.276 , pp. 9149-9157
    • Nugent, C.1    Prins, J.B.2    Whitehead, J.P.3    Wentworth, J.M.4    Chatterjee, V.K.5    O'Rahilly, S.6
  • 75
    • 0033039239 scopus 로고    scopus 로고
    • Basal transepidermal water loss is increased in platelet-type 12-lipoxygenase deficient mice
    • E.N. Johnson, L.B. Nanney, J. Virmani, J.A. Lawson, and C.D. Funk Basal transepidermal water loss is increased in platelet-type 12-lipoxygenase deficient mice J Invest Dermatol 112 1999 861 865
    • (1999) J Invest Dermatol , vol.112 , pp. 861-865
    • Johnson, E.N.1    Nanney, L.B.2    Virmani, J.3    Lawson, J.A.4    Funk, C.D.5
  • 77
    • 0029844659 scopus 로고    scopus 로고
    • Disruption of 12/15-lipoxygenase expression in peritoneal macrophages. Enhanced utilization of the 5-lipoxygenase pathway and diminished oxidation of low density lipoprotein
    • D. Sun, and C.D. Funk Disruption of 12/15-lipoxygenase expression in peritoneal macrophages. Enhanced utilization of the 5-lipoxygenase pathway and diminished oxidation of low density lipoprotein J Biol Chem 271 1996 24055 24062
    • (1996) J Biol Chem , vol.271 , pp. 24055-24062
    • Sun, D.1    Funk, C.D.2
  • 78
    • 77955649322 scopus 로고    scopus 로고
    • Epidermis-type lipoxygenase 3 regulates adipocyte differentiation and peroxisome proliferator-activated receptor gamma activity
    • P. Hallenborg, C. Jorgensen, R.K. Petersen, S. Feddersen, P. Araujo, and P. Markt Epidermis-type lipoxygenase 3 regulates adipocyte differentiation and peroxisome proliferator-activated receptor gamma activity Mol Cell Biol 30 2010 4077 4091
    • (2010) Mol Cell Biol , vol.30 , pp. 4077-4091
    • Hallenborg, P.1    Jorgensen, C.2    Petersen, R.K.3    Feddersen, S.4    Araujo, P.5    Markt, P.6
  • 79
    • 0017119837 scopus 로고
    • Induction of lipogenesis during differentiation in a " preadipocyte" cell line
    • J.C. Mackall, A.K. Student, S.E. Polakis, and M.D. Lane Induction of lipogenesis during differentiation in a "preadipocyte" cell line J Biol Chem 251 1976 6462 6464
    • (1976) J Biol Chem , vol.251 , pp. 6462-6464
    • MacKall, J.C.1    Student, A.K.2    Polakis, S.E.3    Lane, M.D.4
  • 80
    • 67651216391 scopus 로고    scopus 로고
    • Adipokines as regulators of muscle metabolism and insulin sensitivity
    • D.J. Dyck Adipokines as regulators of muscle metabolism and insulin sensitivity Appl Physiol Nutr Metab 34 2009 396 402
    • (2009) Appl Physiol Nutr Metab , vol.34 , pp. 396-402
    • Dyck, D.J.1
  • 81
    • 70349234521 scopus 로고    scopus 로고
    • Increased adipose tissue expression of lipocalin-2 in obesity is related to inflammation and matrix metalloproteinase-2 and metalloproteinase-9 activities in humans
    • V. Catalan, J. Gomez-Ambrosi, A. Rodriguez, B. Ramirez, C. Silva, and F. Rotellar Increased adipose tissue expression of lipocalin-2 in obesity is related to inflammation and matrix metalloproteinase-2 and metalloproteinase-9 activities in humans J Mol Med 87 2009 803 813
    • (2009) J Mol Med , vol.87 , pp. 803-813
    • Catalan, V.1    Gomez-Ambrosi, J.2    Rodriguez, A.3    Ramirez, B.4    Silva, C.5    Rotellar, F.6
  • 82
    • 33845973764 scopus 로고    scopus 로고
    • Lipocalin-2 is an inflammatory marker closely associated with obesity, insulin resistance, and hyperglycemia in humans
    • Y. Wang, K.S. Lam, E.W. Kraegen, G. Sweeney, J. Zhang, and A.W. Tso Lipocalin-2 is an inflammatory marker closely associated with obesity, insulin resistance, and hyperglycemia in humans Clin Chem 53 2007 34 41
    • (2007) Clin Chem , vol.53 , pp. 34-41
    • Wang, Y.1    Lam, K.S.2    Kraegen, E.W.3    Sweeney, G.4    Zhang, J.5    Tso, A.W.6
  • 83
    • 44649173850 scopus 로고    scopus 로고
    • The role of lipocalin 2 in the regulation of inflammation in adipocytes and macrophages
    • J. Zhang, Y. Wu, Y. Zhang, D. Leroith, D.A. Bernlohr, and X. Chen The role of lipocalin 2 in the regulation of inflammation in adipocytes and macrophages Mol Endocrinol 22 2008 1416 1426
    • (2008) Mol Endocrinol , vol.22 , pp. 1416-1426
    • Zhang, J.1    Wu, Y.2    Zhang, Y.3    Leroith, D.4    Bernlohr, D.A.5    Chen, X.6
  • 84
    • 77951193688 scopus 로고    scopus 로고
    • Lipocalin-2 deficiency attenuates insulin resistance associated with aging and obesity
    • I.K. Law, A. Xu, K.S. Lam, T. Berger, T.W. Mak, and P.M. Vanhoutte Lipocalin-2 deficiency attenuates insulin resistance associated with aging and obesity Diabetes 59 2010 872 882
    • (2010) Diabetes , vol.59 , pp. 872-882
    • Law, I.K.1    Xu, A.2    Lam, K.S.3    Berger, T.4    Mak, T.W.5    Vanhoutte, P.M.6
  • 85
    • 77149139835 scopus 로고    scopus 로고
    • Valsartan protects pancreatic islets and adipose tissue from the inflammatory and metabolic consequences of a high-fat diet in mice
    • B.K. Cole, S.R. Keller, R. Wu, J.D. Carter, J.L. Nadler, and C.S. Nunemaker Valsartan protects pancreatic islets and adipose tissue from the inflammatory and metabolic consequences of a high-fat diet in mice Hypertension 55 2010 715 721
    • (2010) Hypertension , vol.55 , pp. 715-721
    • Cole, B.K.1    Keller, S.R.2    Wu, R.3    Carter, J.D.4    Nadler, J.L.5    Nunemaker, C.S.6
  • 86
    • 0032911057 scopus 로고    scopus 로고
    • The diversity of the lipoxygenase family. Many sequence data but little information on biological significance
    • H. Kuhn, and B.J. Thiele The diversity of the lipoxygenase family. Many sequence data but little information on biological significance FEBS Lett 449 1999 7 11
    • (1999) FEBS Lett , vol.449 , pp. 7-11
    • Kuhn, H.1    Thiele, B.J.2
  • 87
    • 0036244676 scopus 로고    scopus 로고
    • The specificity of lipoxygenase-catalyzed lipid peroxidation and the effects of radical-scavenging antioxidants
    • N. Noguchi, H. Yamashita, J. Hamahara, A. Nakamura, H. Kuhn, and E. Niki The specificity of lipoxygenase-catalyzed lipid peroxidation and the effects of radical-scavenging antioxidants Biol Chem 383 2002 619 626
    • (2002) Biol Chem , vol.383 , pp. 619-626
    • Noguchi, N.1    Yamashita, H.2    Hamahara, J.3    Nakamura, A.4    Kuhn, H.5    Niki, E.6
  • 88
    • 33847638020 scopus 로고    scopus 로고
    • Eicosanoids in inflammation: Biosynthesis, pharmacology, and therapeutic frontiers
    • S.P. Khanapure, D.S. Garvey, D.R. Janero, and L.G. Letts Eicosanoids in inflammation: biosynthesis, pharmacology, and therapeutic frontiers Curr Top Med Chem 7 2007 311 340
    • (2007) Curr Top Med Chem , vol.7 , pp. 311-340
    • Khanapure, S.P.1    Garvey, D.S.2    Janero, D.R.3    Letts, L.G.4
  • 89
    • 40349100270 scopus 로고    scopus 로고
    • Endogenous pro-resolving and anti-inflammatory lipid mediators: A new pharmacologic genus
    • C.N. Serhan, and N. Chiang Endogenous pro-resolving and anti-inflammatory lipid mediators: a new pharmacologic genus Br J Pharmacol 153 Suppl 1 2008 S200 S215
    • (2008) Br J Pharmacol , vol.153 , Issue.SUPPL. 1
    • Serhan, C.N.1    Chiang, N.2
  • 90
    • 42649089790 scopus 로고    scopus 로고
    • Resolving inflammation: Dual anti-inflammatory and pro-resolution lipid mediators
    • C.N. Serhan, N. Chiang, and T.E. Van Dyke Resolving inflammation: dual anti-inflammatory and pro-resolution lipid mediators Nat Rev Immunol 8 2008 349 361
    • (2008) Nat Rev Immunol , vol.8 , pp. 349-361
    • Serhan, C.N.1    Chiang, N.2    Van Dyke, T.E.3
  • 91
    • 41749090254 scopus 로고    scopus 로고
    • Anti-inflammatory and proresolving lipid mediators
    • C.N. Serhan, S. Yacoubian, and R. Yang Anti-inflammatory and proresolving lipid mediators Ann Rev Pathol 3 2008 279 312
    • (2008) Ann Rev Pathol , vol.3 , pp. 279-312
    • Serhan, C.N.1    Yacoubian, S.2    Yang, R.3
  • 92
    • 68049118447 scopus 로고    scopus 로고
    • Role of arachidonic acid lipoxygenase metabolites in the regulation of vascular tone
    • Y. Chawengsub, K.M. Gauthier, and W.B. Campbell Role of arachidonic acid lipoxygenase metabolites in the regulation of vascular tone Am J Physiol Heart Circ Physiol 297 2009 H495 H507
    • (2009) Am J Physiol Heart Circ Physiol , vol.297
    • Chawengsub, Y.1    Gauthier, K.M.2    Campbell, W.B.3
  • 95
    • 33644824103 scopus 로고    scopus 로고
    • Reticulocyte 15-lipoxygenase-I is important in acetylcholine-induced endothelium-dependent vasorelaxation in rabbit aorta
    • X. Tang, B.B. Holmes, K. Nithipatikom, C.J. Hillard, H. Kuhn, and W.B. Campbell Reticulocyte 15-lipoxygenase-I is important in acetylcholine-induced endothelium-dependent vasorelaxation in rabbit aorta Arterioscler Thromb Vasc Biol 26 2006 78 84
    • (2006) Arterioscler Thromb Vasc Biol , vol.26 , pp. 78-84
    • Tang, X.1    Holmes, B.B.2    Nithipatikom, K.3    Hillard, C.J.4    Kuhn, H.5    Campbell, W.B.6
  • 96
    • 0023920874 scopus 로고
    • Arachidonate 15-lipoxygenase (omega-6 lipoxygenase) from human leukocytes. Purification and structural homology to other mammalian lipoxygenases
    • E. Sigal, D. Grunberger, C.S. Craik, G.H. Caughey, and J.A. Nadel Arachidonate 15-lipoxygenase (omega-6 lipoxygenase) from human leukocytes. Purification and structural homology to other mammalian lipoxygenases J Biol Chem 263 1988 5328 5332
    • (1988) J Biol Chem , vol.263 , pp. 5328-5332
    • Sigal, E.1    Grunberger, D.2    Craik, C.S.3    Caughey, G.H.4    Nadel, J.A.5
  • 97
    • 0026541324 scopus 로고
    • Effects of various cyclooxygenase and lipoxygenase metabolites on guinea-pig cerebral arteries
    • T.K. Uski, and E.D. Hogestatt Effects of various cyclooxygenase and lipoxygenase metabolites on guinea-pig cerebral arteries Gen Pharmacol 23 1992 109 113
    • (1992) Gen Pharmacol , vol.23 , pp. 109-113
    • Uski, T.K.1    Hogestatt, E.D.2
  • 98
    • 13244290059 scopus 로고    scopus 로고
    • Nitric oxide, peroxynitrite and lipoxygenase in atherogenesis: Mechanistic insights
    • H. Rubbo, and V. O'Donnell Nitric oxide, peroxynitrite and lipoxygenase in atherogenesis: mechanistic insights Toxicology 208 2005 305 317
    • (2005) Toxicology , vol.208 , pp. 305-317
    • Rubbo, H.1    O'Donnell, V.2
  • 99
    • 0030993186 scopus 로고    scopus 로고
    • A kinetic model for the interaction of nitric oxide with a mammalian lipoxygenase
    • H.G. Holzhutter, R. Wiesner, J. Rathmann, R. Stosser, and H. Kuhn A kinetic model for the interaction of nitric oxide with a mammalian lipoxygenase Eur J Biochem 245 1997 608 616
    • (1997) Eur J Biochem , vol.245 , pp. 608-616
    • Holzhutter, H.G.1    Wiesner, R.2    Rathmann, J.3    Stosser, R.4    Kuhn, H.5
  • 100
    • 0034933878 scopus 로고    scopus 로고
    • Catalytic consumption of nitric oxide by 12/15-lipoxygenase: Inhibition of monocyte soluble guanylate cyclase activation
    • M.J. Coffey, R. Natarajan, P.H. Chumley, B. Coles, P.R. Thimmalapura, and M. Nowell Catalytic consumption of nitric oxide by 12/15-lipoxygenase: inhibition of monocyte soluble guanylate cyclase activation Proc Natl Acad Sci USA 98 2001 8006 8011
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 8006-8011
    • Coffey, M.J.1    Natarajan, R.2    Chumley, P.H.3    Coles, B.4    Thimmalapura, P.R.5    Nowell, M.6
  • 101
    • 14644426612 scopus 로고    scopus 로고
    • Elevated endothelial nitric oxide bioactivity and resistance to angiotensin-dependent hypertension in 12/15-lipoxygenase knockout mice
    • P.B. Anning, B. Coles, A. Bermudez-Fajardo, P.E. Martin, B.S. Levison, and S.L. Hazen Elevated endothelial nitric oxide bioactivity and resistance to angiotensin-dependent hypertension in 12/15-lipoxygenase knockout mice Am J Pathol 166 2005 653 662
    • (2005) Am J Pathol , vol.166 , pp. 653-662
    • Anning, P.B.1    Coles, B.2    Bermudez-Fajardo, A.3    Martin, P.E.4    Levison, B.S.5    Hazen, S.L.6
  • 102
    • 0037687982 scopus 로고    scopus 로고
    • Chronic hypoxia activates lung 15-lipoxygenase, which catalyzes production of 15-HETE and enhances constriction in neonatal rabbit pulmonary arteries
    • D. Zhu, M. Medhora, W.B. Campbell, N. Spitzbarth, J.E. Baker, and E.R. Jacobs Chronic hypoxia activates lung 15-lipoxygenase, which catalyzes production of 15-HETE and enhances constriction in neonatal rabbit pulmonary arteries Circ Res. 92 2003 992 1000
    • (2003) Circ Res. , vol.92 , pp. 992-1000
    • Zhu, D.1    Medhora, M.2    Campbell, W.B.3    Spitzbarth, N.4    Baker, J.E.5    Jacobs, E.R.6
  • 103
    • 0029964098 scopus 로고    scopus 로고
    • Vasorelaxation by an endothelium-derived metabolite of arachidonic acid
    • S.L. Pfister, N. Spitzbarth, W. Edgemond, and W.B. Campbell Vasorelaxation by an endothelium-derived metabolite of arachidonic acid Am J Physiol 270 1996 H1021 H1030
    • (1996) Am J Physiol , vol.270
    • Pfister, S.L.1    Spitzbarth, N.2    Edgemond, W.3    Campbell, W.B.4
  • 104
    • 0032553415 scopus 로고    scopus 로고
    • Identification of the 11, 14, 15- and 11, 12, 15-trihydroxyeicosatrienoic acids as endothelium-derived relaxing factors of rabbit aorta
    • S.L. Pfister, N. Spitzbarth, K. Nithipatikom, W.S. Edgemond, J.R. Falck, and W.B. Campbell Identification of the 11, 14, 15- and 11, 12, 15-trihydroxyeicosatrienoic acids as endothelium-derived relaxing factors of rabbit aorta J Biol Chem 273 1998 30879 30887
    • (1998) J Biol Chem , vol.273 , pp. 30879-30887
    • Pfister, S.L.1    Spitzbarth, N.2    Nithipatikom, K.3    Edgemond, W.S.4    Falck, J.R.5    Campbell, W.B.6
  • 105
    • 71449107550 scopus 로고    scopus 로고
    • Identification of 13-hydroxy-14, 15-epoxyeicosatrienoic acid as an acid-stable endothelium-derived hyperpolarizing factor in rabbit arteries
    • Y. Chawengsub, K.M. Gauthier, K. Nithipatikom, B.D. Hammock, J.R. Falck, and D. Narsimhaswamy Identification of 13-hydroxy-14, 15-epoxyeicosatrienoic acid as an acid-stable endothelium-derived hyperpolarizing factor in rabbit arteries J Biol Chem 284 2009 31280 31290
    • (2009) J Biol Chem , vol.284 , pp. 31280-31290
    • Chawengsub, Y.1    Gauthier, K.M.2    Nithipatikom, K.3    Hammock, B.D.4    Falck, J.R.5    Narsimhaswamy, D.6
  • 106
    • 0023851897 scopus 로고
    • Eicosanoid metabolism in cerebromicrovascular endothelium
    • S.A. Moore, A.A. Spector, and M.N. Hart Eicosanoid metabolism in cerebromicrovascular endothelium Am J Physiol 254 1988 C37 C44
    • (1988) Am J Physiol , vol.254
    • Moore, S.A.1    Spector, A.A.2    Hart, M.N.3
  • 110
    • 33644849675 scopus 로고    scopus 로고
    • Epoxyeicosatrienoic and dihydroxyeicosatrienoic acids dilate human coronary arterioles via BK(Ca) channels: Implications for soluble epoxide hydrolase inhibition
    • B.T. Larsen, H. Miura, O.A. Hatoum, W.B. Campbell, B.D. Hammock, and D.C. Zeldin Epoxyeicosatrienoic and dihydroxyeicosatrienoic acids dilate human coronary arterioles via BK(Ca) channels: implications for soluble epoxide hydrolase inhibition Am J Physiol Heart Circ Physiol 290 2006 H491 H499
    • (2006) Am J Physiol Heart Circ Physiol , vol.290
    • Larsen, B.T.1    Miura, H.2    Hatoum, O.A.3    Campbell, W.B.4    Hammock, B.D.5    Zeldin, D.C.6
  • 111
    • 0026050962 scopus 로고
    • Effects of 12-HETE on isolated dog renal arcuate arteries
    • Y.H. Ma, D.R. Harder, J.E. Clark, and R.J. Roman Effects of 12-HETE on isolated dog renal arcuate arteries Am J Physiol 261 1991 H451 H456
    • (1991) Am J Physiol , vol.261
    • Ma, Y.H.1    Harder, D.R.2    Clark, J.E.3    Roman, R.J.4
  • 113
    • 0025767695 scopus 로고
    • Hepoxilin A3 (HxA3) is formed by the rat aorta and is metabolized into HxA3-C, a glutathione conjugate
    • O. Laneuville, E.J. Corey, R. Couture, and C.R. Pace-Asciak Hepoxilin A3 (HxA3) is formed by the rat aorta and is metabolized into HxA3-C, a glutathione conjugate Biochim Biophys Acta 1084 1991 60 68
    • (1991) Biochim Biophys Acta , vol.1084 , pp. 60-68
    • Laneuville, O.1    Corey, E.J.2    Couture, R.3    Pace-Asciak, C.R.4
  • 114
    • 0028349403 scopus 로고
    • Lipoxin biosynthesis and its impact in inflammatory and vascular events
    • C.N. Serhan Lipoxin biosynthesis and its impact in inflammatory and vascular events Biochim Biophys Acta 1212 1994 1 25
    • (1994) Biochim Biophys Acta , vol.1212 , pp. 1-25
    • Serhan, C.N.1
  • 115
    • 0023612099 scopus 로고
    • The mitogenic effect of 15- and 12-hydroxyeicosatetraenoic acid on endothelial cells may be mediated via diacylglycerol kinase inhibition
    • B.N. Setty, J.E. Graeber, and M.J. Stuart The mitogenic effect of 15- and 12-hydroxyeicosatetraenoic acid on endothelial cells may be mediated via diacylglycerol kinase inhibition J Biol Chem 262 1987 17613 17622
    • (1987) J Biol Chem , vol.262 , pp. 17613-17622
    • Setty, B.N.1    Graeber, J.E.2    Stuart, M.J.3
  • 116
    • 0028589154 scopus 로고
    • Activation of mitogen-activated protein kinases by arachidonic acid and its metabolites in vascular smooth muscle cells
    • G.N. Rao, A.S. Baas, W.C. Glasgow, T.E. Eling, M.S. Runge, and R.W. Alexander Activation of mitogen-activated protein kinases by arachidonic acid and its metabolites in vascular smooth muscle cells J Biol Chem 269 1994 32586 32591
    • (1994) J Biol Chem , vol.269 , pp. 32586-32591
    • Rao, G.N.1    Baas, A.S.2    Glasgow, W.C.3    Eling, T.E.4    Runge, M.S.5    Alexander, R.W.6
  • 117
    • 1842715005 scopus 로고    scopus 로고
    • Regulation of monocyte chemoattractant protein-1 by the oxidized lipid, 13-hydroperoxyoctadecadienoic acid, in vascular smooth muscle cells via nuclear factor-kappa B (NF-kappa B)
    • R.S. Dwarakanath, S. Sahar, M.A. Reddy, D. Castanotto, J.J. Rossi, and R. Natarajan Regulation of monocyte chemoattractant protein-1 by the oxidized lipid, 13-hydroperoxyoctadecadienoic acid, in vascular smooth muscle cells via nuclear factor-kappa B (NF-kappa B) J Mol Cell Cardiol 36 2004 585 595
    • (2004) J Mol Cell Cardiol , vol.36 , pp. 585-595
    • Dwarakanath, R.S.1    Sahar, S.2    Reddy, M.A.3    Castanotto, D.4    Rossi, J.J.5    Natarajan, R.6
  • 118
    • 73949150404 scopus 로고    scopus 로고
    • ROCK pathway participates in the processes that 15- hydroxyeicosatetraenoic acid (15-HETE) mediated the pulmonary vascular remodeling induced by hypoxia in rat
    • J. Ma, S. Liang, Z. Wang, L. Zhang, J. Jiang, and J. Zheng ROCK pathway participates in the processes that 15-hydroxyeicosatetraenoic acid (15-HETE) mediated the pulmonary vascular remodeling induced by hypoxia in rat J Cell Physiol 222 2010 82 94
    • (2010) J Cell Physiol , vol.222 , pp. 82-94
    • Ma, J.1    Liang, S.2    Wang, Z.3    Zhang, L.4    Jiang, J.5    Zheng, J.6
  • 119
    • 0028130811 scopus 로고
    • 13-HODE increases intracellular calcium in vascular smooth muscle cells
    • L.L. Stoll, M.R. Morland, and A.A. Spector 13-HODE increases intracellular calcium in vascular smooth muscle cells Am J Physiol 266 1994 C990 C996
    • (1994) Am J Physiol , vol.266
    • Stoll, L.L.1    Morland, M.R.2    Spector, A.A.3
  • 120
    • 0035853386 scopus 로고    scopus 로고
    • Adenoviral delivery of a leukocyte-type 12 lipoxygenase ribozyme inhibits effects of glucose and platelet-derived growth factor in vascular endothelial and smooth muscle cells
    • M.K. Patricia, R. Natarajan, A.N. Dooley, F. Hernandez, J.L. Gu, and J.A. Berliner Adenoviral delivery of a leukocyte-type 12 lipoxygenase ribozyme inhibits effects of glucose and platelet-derived growth factor in vascular endothelial and smooth muscle cells Circ Res 88 2001 659 665
    • (2001) Circ Res , vol.88 , pp. 659-665
    • Patricia, M.K.1    Natarajan, R.2    Dooley, A.N.3    Hernandez, F.4    Gu, J.L.5    Berliner, J.A.6
  • 121
    • 66349103988 scopus 로고    scopus 로고
    • CREB-mediated IL-6 expression is required for 15(S)- hydroxyeicosatetraenoic acid-induced vascular smooth muscle cell migration
    • K.R. Chava, M. Karpurapu, D. Wang, M. Bhanoori, V. Kundumani-Sridharan, and Q. Zhang CREB-mediated IL-6 expression is required for 15(S)- hydroxyeicosatetraenoic acid-induced vascular smooth muscle cell migration Arterioscler Thromb Vasc Biol 29 2009 809 815
    • (2009) Arterioscler Thromb Vasc Biol , vol.29 , pp. 809-815
    • Chava, K.R.1    Karpurapu, M.2    Wang, D.3    Bhanoori, M.4    Kundumani-Sridharan, V.5    Zhang, Q.6
  • 122
    • 71449108959 scopus 로고    scopus 로고
    • Src-dependent STAT-3-mediated expression of monocyte chemoattractant protein-1 is required for 15(S)-hydroxyeicosatetraenoic acid-induced vascular smooth muscle cell migration
    • H.S. Potula, D. Wang, D.V. Quyen, N.K. Singh, V. Kundumani-Sridharan, and M. Karpurapu Src-dependent STAT-3-mediated expression of monocyte chemoattractant protein-1 is required for 15(S)-hydroxyeicosatetraenoic acid-induced vascular smooth muscle cell migration J Biol Chem 284 2009 31142 31155
    • (2009) J Biol Chem , vol.284 , pp. 31142-31155
    • Potula, H.S.1    Wang, D.2    Quyen, D.V.3    Singh, N.K.4    Kundumani-Sridharan, V.5    Karpurapu, M.6
  • 123
    • 0038458816 scopus 로고    scopus 로고
    • Reduced growth factor responses in vascular smooth muscle cells derived from 12/15-lipoxygenase-deficient mice
    • M.A. Reddy, Y.S. Kim, L. Lanting, and R. Natarajan Reduced growth factor responses in vascular smooth muscle cells derived from 12/15-lipoxygenase- deficient mice Hypertension 41 2003 1294 1300
    • (2003) Hypertension , vol.41 , pp. 1294-1300
    • Reddy, M.A.1    Kim, Y.S.2    Lanting, L.3    Natarajan, R.4
  • 124
    • 74849085099 scopus 로고    scopus 로고
    • 15-HETE protects rat pulmonary arterial smooth muscle cells from apoptosis via the PI3K/Akt pathway
    • S. Wang, Y. Wang, J. Jiang, R. Wang, L. Li, and Z. Qiu 15-HETE protects rat pulmonary arterial smooth muscle cells from apoptosis via the PI3K/Akt pathway Prostaglandins Other Lipid Mediat 91 2010 51 60
    • (2010) Prostaglandins Other Lipid Mediat , vol.91 , pp. 51-60
    • Wang, S.1    Wang, Y.2    Jiang, J.3    Wang, R.4    Li, L.5    Qiu, Z.6
  • 125
    • 77955454197 scopus 로고    scopus 로고
    • Review: Potential role of the lipoxygenase derived lipid mediators in atherosclerosis: Leukotrienes, lipoxins and resolvins
    • Hersberger M. Review: Potential role of the lipoxygenase derived lipid mediators in atherosclerosis: leukotrienes, lipoxins and resolvins. Clin Chem Lab Med. 2010.
    • (2010) Clin Chem Lab Med
    • Hersberger, M.1
  • 126
    • 0033812812 scopus 로고    scopus 로고
    • Overexpression of 15-lipoxygenase in vascular endothelium accelerates early atherosclerosis in LDL receptor-deficient mice
    • D. Harats, A. Shaish, J. George, M. Mulkins, H. Kurihara, and H. Levkovitz Overexpression of 15-lipoxygenase in vascular endothelium accelerates early atherosclerosis in LDL receptor-deficient mice Arterioscler Thromb Vasc Biol 20 2000 2100 2105
    • (2000) Arterioscler Thromb Vasc Biol , vol.20 , pp. 2100-2105
    • Harats, D.1    Shaish, A.2    George, J.3    Mulkins, M.4    Kurihara, H.5    Levkovitz, H.6
  • 127
    • 0029829533 scopus 로고    scopus 로고
    • Macrophage-mediated 15-lipoxygenase expression protects against atherosclerosis development
    • J. Shen, E. Herderick, J.F. Cornhill, E. Zsigmond, H.S. Kim, and H. Kuhn Macrophage-mediated 15-lipoxygenase expression protects against atherosclerosis development J Clin Invest 98 1996 2201 2208
    • (1996) J Clin Invest , vol.98 , pp. 2201-2208
    • Shen, J.1    Herderick, E.2    Cornhill, J.F.3    Zsigmond, E.4    Kim, H.S.5    Kuhn, H.6
  • 128
    • 0036893747 scopus 로고    scopus 로고
    • Transient experimental anemia in cholesterol-fed rabbits induces systemic overexpression of the reticulocyte-type 15-lipoxygenase and protects from aortic lipid deposition
    • F. Trebus, D. Heydeck, I. Schimke, C. Gerth, and H. Kuhn Transient experimental anemia in cholesterol-fed rabbits induces systemic overexpression of the reticulocyte-type 15-lipoxygenase and protects from aortic lipid deposition Prostaglandins Leukot Essent Fatty Acids 67 2002 419 428
    • (2002) Prostaglandins Leukot Essent Fatty Acids , vol.67 , pp. 419-428
    • Trebus, F.1    Heydeck, D.2    Schimke, I.3    Gerth, C.4    Kuhn, H.5
  • 129
    • 0032752579 scopus 로고    scopus 로고
    • Disruption of the 12/15-lipoxygenase gene diminishes atherosclerosis in apo E-deficient mice
    • T. Cyrus, J.L. Witztum, D.J. Rader, R. Tangirala, S. Fazio, and M.F. Linton Disruption of the 12/15-lipoxygenase gene diminishes atherosclerosis in apo E-deficient mice J Clin Invest 103 1999 1597 1604
    • (1999) J Clin Invest , vol.103 , pp. 1597-1604
    • Cyrus, T.1    Witztum, J.L.2    Rader, D.J.3    Tangirala, R.4    Fazio, S.5    Linton, M.F.6
  • 130
    • 0035826892 scopus 로고    scopus 로고
    • Absence of 12/15-lipoxygenase expression decreases lipid peroxidation and atherogenesis in apolipoprotein e-deficient mice
    • T. Cyrus, D. Pratico, L. Zhao, J.L. Witztum, D.J. Rader, and J. Rokach Absence of 12/15-lipoxygenase expression decreases lipid peroxidation and atherogenesis in apolipoprotein e-deficient mice Circulation 103 2001 2277 2282
    • (2001) Circulation , vol.103 , pp. 2277-2282
    • Cyrus, T.1    Pratico, D.2    Zhao, L.3    Witztum, J.L.4    Rader, D.J.5    Rokach, J.6
  • 131
    • 20844446795 scopus 로고    scopus 로고
    • Critical role of macrophage 12/15-lipoxygenase for atherosclerosis in apolipoprotein E-deficient mice
    • Y. Huo, L. Zhao, M.C. Hyman, P. Shashkin, B.L. Harry, and T. Burcin Critical role of macrophage 12/15-lipoxygenase for atherosclerosis in apolipoprotein E-deficient mice Circulation 110 2004 2024 2031
    • (2004) Circulation , vol.110 , pp. 2024-2031
    • Huo, Y.1    Zhao, L.2    Hyman, M.C.3    Shashkin, P.4    Harry, B.L.5    Burcin, T.6
  • 132
    • 24344510350 scopus 로고    scopus 로고
    • Anti-inflammatory circuitry: Lipoxin, aspirin-triggered lipoxins and their receptor ALX
    • N. Chiang, M. Arita, and C.N. Serhan Anti-inflammatory circuitry: lipoxin, aspirin-triggered lipoxins and their receptor ALX Prostaglandins Leukot Essent Fatty Acids 73 2005 163 177
    • (2005) Prostaglandins Leukot Essent Fatty Acids , vol.73 , pp. 163-177
    • Chiang, N.1    Arita, M.2    Serhan, C.N.3
  • 133
    • 68949116297 scopus 로고    scopus 로고
    • Dual 12/15- and 5-lipoxygenase deficiency in macrophages alters arachidonic acid metabolism and attenuates peritonitis and atherosclerosis in ApoE knock-out mice
    • D. Poeckel, K.A. Zemski Berry, R.C. Murphy, and C.D. Funk Dual 12/15- and 5-lipoxygenase deficiency in macrophages alters arachidonic acid metabolism and attenuates peritonitis and atherosclerosis in ApoE knock-out mice J Biol Chem 284 2009 21077 21089
    • (2009) J Biol Chem , vol.284 , pp. 21077-21089
    • Poeckel, D.1    Zemski Berry, K.A.2    Murphy, R.C.3    Funk, C.D.4
  • 135
    • 0025756633 scopus 로고
    • Evidence for a dominant role of lipoxygenase(s) in the oxidation of LDL by mouse peritoneal macrophages
    • S.M. Rankin, S. Parthasarathy, and D. Steinberg Evidence for a dominant role of lipoxygenase(s) in the oxidation of LDL by mouse peritoneal macrophages J Lipid Res 32 1991 449 456
    • (1991) J Lipid Res , vol.32 , pp. 449-456
    • Rankin, S.M.1    Parthasarathy, S.2    Steinberg, D.3
  • 136
    • 0031471792 scopus 로고    scopus 로고
    • Fibroblasts that overexpress 15-lipoxygenase generate bioactive and minimally modified LDL
    • F. Sigari, C. Lee, J.L. Witztum, and P.D. Reaven Fibroblasts that overexpress 15-lipoxygenase generate bioactive and minimally modified LDL Arterioscler Thromb Vasc Biol 17 1997 3639 3645
    • (1997) Arterioscler Thromb Vasc Biol , vol.17 , pp. 3639-3645
    • Sigari, F.1    Lee, C.2    Witztum, J.L.3    Reaven, P.D.4
  • 137
    • 0031441612 scopus 로고    scopus 로고
    • Cytokine modulation of LDL oxidation by activated human monocytes
    • V.A. Folcik, R. Aamir, and M.K. Cathcart Cytokine modulation of LDL oxidation by activated human monocytes Arterioscler Thromb Vasc Biol 17 1997 1954 1961
    • (1997) Arterioscler Thromb Vasc Biol , vol.17 , pp. 1954-1961
    • Folcik, V.A.1    Aamir, R.2    Cathcart, M.K.3
  • 138
    • 0037968682 scopus 로고    scopus 로고
    • Low density lipoprotein receptor-related protein-mediated membrane translocation of 12/15-lipoxygenase is required for oxidation of low density lipoprotein by macrophages
    • H. Zhu, Y. Takahashi, W. Xu, H. Kawajiri, T. Murakami, and M. Yamamoto Low density lipoprotein receptor-related protein-mediated membrane translocation of 12/15-lipoxygenase is required for oxidation of low density lipoprotein by macrophages J Biol Chem 278 2003 13350 13355
    • (2003) J Biol Chem , vol.278 , pp. 13350-13355
    • Zhu, H.1    Takahashi, Y.2    Xu, W.3    Kawajiri, H.4    Murakami, T.5    Yamamoto, M.6
  • 139
    • 27544444125 scopus 로고    scopus 로고
    • Selective uptake and efflux of cholesteryl linoleate in LDL by macrophages expressing 12/15-lipoxygenase
    • Y. Takahashi, H. Zhu, W. Xu, T. Murakami, T. Iwasaki, and H. Hattori Selective uptake and efflux of cholesteryl linoleate in LDL by macrophages expressing 12/15-lipoxygenase Biochem Biophys Res Commun 338 2005 128 135
    • (2005) Biochem Biophys Res Commun , vol.338 , pp. 128-135
    • Takahashi, Y.1    Zhu, H.2    Xu, W.3    Murakami, T.4    Iwasaki, T.5    Hattori, H.6
  • 140
    • 53449092580 scopus 로고    scopus 로고
    • 12/15-Lipoxygenase activity increases the degradation of macrophage ATP-binding cassette transporter G1
    • M.H. Nagelin, S. Srinivasan, J. Lee, J.L. Nadler, and C.C. Hedrick 12/15-Lipoxygenase activity increases the degradation of macrophage ATP-binding cassette transporter G1 Arterioscler Thromb Vasc Biol 28 2008 1811 1819
    • (2008) Arterioscler Thromb Vasc Biol , vol.28 , pp. 1811-1819
    • Nagelin, M.H.1    Srinivasan, S.2    Lee, J.3    Nadler, J.L.4    Hedrick, C.C.5
  • 141
    • 71449105303 scopus 로고    scopus 로고
    • Murine 12/15-lipoxygenase regulates ATP-binding cassette transporter G1 protein degradation through p38- and JNK2-dependent pathways
    • M.H. Nagelin, S. Srinivasan, J.L. Nadler, and C.C. Hedrick Murine 12/15-lipoxygenase regulates ATP-binding cassette transporter G1 protein degradation through p38- and JNK2-dependent pathways J Biol Chem 284 2009 31303 31314
    • (2009) J Biol Chem , vol.284 , pp. 31303-31314
    • Nagelin, M.H.1    Srinivasan, S.2    Nadler, J.L.3    Hedrick, C.C.4
  • 142
    • 0042737910 scopus 로고    scopus 로고
    • Low high-density lipoprotein cholesterol: Physiological background, clinical importance and drug treatment
    • M. Hersberger, and A. von Eckardstein Low high-density lipoprotein cholesterol: physiological background, clinical importance and drug treatment Drugs 63 2003 1907 1945
    • (2003) Drugs , vol.63 , pp. 1907-1945
    • Hersberger, M.1    Von Eckardstein, A.2
  • 143
    • 33745610718 scopus 로고    scopus 로고
    • Modified HDL: Biological and physiopathological consequences
    • G.D. Norata, A. Pirillo, and A.L. Catapano Modified HDL: biological and physiopathological consequences Nutr Metab Cardiovasc Dis 16 2006 371 386
    • (2006) Nutr Metab Cardiovasc Dis , vol.16 , pp. 371-386
    • Norata, G.D.1    Pirillo, A.2    Catapano, A.L.3
  • 144
    • 33646128719 scopus 로고    scopus 로고
    • 15-Lipoxygenase-mediated modification of high-density lipoproteins impairs SR-BI- and ABCA1-dependent cholesterol efflux from macrophages
    • A. Pirillo, P. Uboldi, H. Kuhn, and A.L. Catapano 15-Lipoxygenase- mediated modification of high-density lipoproteins impairs SR-BI- and ABCA1-dependent cholesterol efflux from macrophages Biochim Biophys Acta 1761 2006 292 300
    • (2006) Biochim Biophys Acta , vol.1761 , pp. 292-300
    • Pirillo, A.1    Uboldi, P.2    Kuhn, H.3    Catapano, A.L.4
  • 145
    • 53149097776 scopus 로고    scopus 로고
    • The 15-lipoxygenase-modified high density lipoproteins 3 fail to inhibit the TNF-alpha-induced inflammatory response in human endothelial cells
    • A. Pirillo, P. Uboldi, C. Bolego, H. Kuhn, and A.L. Catapano The 15-lipoxygenase-modified high density lipoproteins 3 fail to inhibit the TNF-alpha-induced inflammatory response in human endothelial cells J Immunol 181 2008 2821 2830
    • (2008) J Immunol , vol.181 , pp. 2821-2830
    • Pirillo, A.1    Uboldi, P.2    Bolego, C.3    Kuhn, H.4    Catapano, A.L.5
  • 146
    • 0028998879 scopus 로고
    • A leukocyte type of 12-lipoxygenase is expressed in human vascular and mononuclear cells. Evidence for upregulation by angiotensin II
    • J.A. Kim, J.L. Gu, R. Natarajan, J.A. Berliner, and J.L. Nadler A leukocyte type of 12-lipoxygenase is expressed in human vascular and mononuclear cells. Evidence for upregulation by angiotensin II Arterioscler Thromb Vasc Biol 15 1995 942 948
    • (1995) Arterioscler Thromb Vasc Biol , vol.15 , pp. 942-948
    • Kim, J.A.1    Gu, J.L.2    Natarajan, R.3    Berliner, J.A.4    Nadler, J.L.5
  • 147
    • 10744233434 scopus 로고    scopus 로고
    • 12/15-Lipoxygenase activity mediates inflammatory monocyte/endothelial interactions and atherosclerosis in vivo
    • K.B. Reilly, S. Srinivasan, M.E. Hatley, M.K. Patricia, J. Lannigan, and D.T. Bolick 12/15-Lipoxygenase activity mediates inflammatory monocyte/endothelial interactions and atherosclerosis in vivo J Biol Chem 279 2004 9440 9450
    • (2004) J Biol Chem , vol.279 , pp. 9440-9450
    • Reilly, K.B.1    Srinivasan, S.2    Hatley, M.E.3    Patricia, M.K.4    Lannigan, J.5    Bolick, D.T.6
  • 148
    • 0342281480 scopus 로고    scopus 로고
    • Transient overexpression of human 15-lipoxygenase in aortic endothelial cells enhances tumor necrosis factor-induced vascular cell adhesion molecule-1 gene expression
    • J. Wolle, K.A. Welch, L.J. Devall, J.A. Cornicelli, and U. Saxena Transient overexpression of human 15-lipoxygenase in aortic endothelial cells enhances tumor necrosis factor-induced vascular cell adhesion molecule-1 gene expression Biochem Biophys Res Commun 220 1996 310 314
    • (1996) Biochem Biophys Res Commun , vol.220 , pp. 310-314
    • Wolle, J.1    Welch, K.A.2    Devall, L.J.3    Cornicelli, J.A.4    Saxena, U.5
  • 149
    • 0033086392 scopus 로고    scopus 로고
    • High expression of human 15-lipoxygenase induces NF-kappaB-mediated expression of vascular cell adhesion molecule 1, intercellular adhesion molecule 1, and T-cell adhesion on human endothelial cells
    • H. Viita, C.K. Sen, S. Roy, T. Siljamaki, T. Nikkari, and S. Yla-Herttuala High expression of human 15-lipoxygenase induces NF-kappaB-mediated expression of vascular cell adhesion molecule 1, intercellular adhesion molecule 1, and T-cell adhesion on human endothelial cells Antioxid Redox Signal 1 1999 83 96
    • (1999) Antioxid Redox Signal , vol.1 , pp. 83-96
    • Viita, H.1    Sen, C.K.2    Roy, S.3    Siljamaki, T.4    Nikkari, T.5    Yla-Herttuala, S.6
  • 150
    • 27644571486 scopus 로고    scopus 로고
    • 12/15-lipoxygenase regulates intercellular adhesion molecule-1 expression and monocyte adhesion to endothelium through activation of RhoA and nuclear factor-kappaB
    • D.T. Bolick, A.W. Orr, A. Whetzel, S. Srinivasan, M.E. Hatley, and M.A. Schwartz 12/15-lipoxygenase regulates intercellular adhesion molecule-1 expression and monocyte adhesion to endothelium through activation of RhoA and nuclear factor-kappaB Arterioscler Thromb Vasc Biol 25 2005 2301 2307
    • (2005) Arterioscler Thromb Vasc Biol , vol.25 , pp. 2301-2307
    • Bolick, D.T.1    Orr, A.W.2    Whetzel, A.3    Srinivasan, S.4    Hatley, M.E.5    Schwartz, M.A.6
  • 153
    • 0027270732 scopus 로고
    • Transmembrane signaling in human polymorphonuclear neutrophils: 15(S)-hydroxy-(5Z, 8Z, 11Z, 13E)-eicosatetraenoic acid modulates receptor agonist-triggered cell activation
    • R.J. Smith, J.M. Justen, E.G. Nidy, L.M. Sam, and J.E. Bleasdale Transmembrane signaling in human polymorphonuclear neutrophils: 15(S)-hydroxy-(5Z, 8Z, 11Z, 13E)-eicosatetraenoic acid modulates receptor agonist-triggered cell activation Proc Natl Acad Sci USA 90 1993 7270 7274
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 7270-7274
    • Smith, R.J.1    Justen, J.M.2    Nidy, E.G.3    Sam, L.M.4    Bleasdale, J.E.5
  • 154
    • 0028169226 scopus 로고
    • 15-Hydroxyeicosatetraenoic acid inhibits neutrophil migration across cytokine-activated endothelium
    • S. Takata, A. Papayianni, M. Matsubara, W. Jimenez, P.H. Pronovost, and H.R. Brady 15-Hydroxyeicosatetraenoic acid inhibits neutrophil migration across cytokine-activated endothelium Am J Pathol 145 1994 541 549
    • (1994) Am J Pathol , vol.145 , pp. 541-549
    • Takata, S.1    Papayianni, A.2    Matsubara, M.3    Jimenez, W.4    Pronovost, P.H.5    Brady, H.R.6
  • 156
    • 0027265208 scopus 로고
    • Localization of 13-hydroxyoctadecadienoic acid and the vitronectin receptor in human endothelial cells and endothelial cell/platelet interactions in vitro
    • M.R. Buchanan, M.C. Bertomeu, T.A. Haas, F.W. Orr, and L.L. Eltringham-Smith Localization of 13-hydroxyoctadecadienoic acid and the vitronectin receptor in human endothelial cells and endothelial cell/platelet interactions in vitro Blood 81 1993 3303 3312
    • (1993) Blood , vol.81 , pp. 3303-3312
    • Buchanan, M.R.1    Bertomeu, M.C.2    Haas, T.A.3    Orr, F.W.4    Eltringham-Smith, L.L.5
  • 157
    • 0031886864 scopus 로고    scopus 로고
    • The peroxisome proliferator-activated receptor-gamma is a negative regulator of macrophage activation
    • M. Ricote, A.C. Li, T.M. Willson, C.J. Kelly, and C.K. Glass The peroxisome proliferator-activated receptor-gamma is a negative regulator of macrophage activation Nature 391 1998 79 82
    • (1998) Nature , vol.391 , pp. 79-82
    • Ricote, M.1    Li, A.C.2    Willson, T.M.3    Kelly, C.J.4    Glass, C.K.5
  • 158
    • 0036160759 scopus 로고    scopus 로고
    • Role of 12-lipoxygenase and oxidant stress in hyperglycaemia-induced acceleration of atherosclerosis in a diabetic pig model
    • R. Natarajan, R.G. Gerrity, J.L. Gu, L. Lanting, L. Thomas, and J.L. Nadler Role of 12-lipoxygenase and oxidant stress in hyperglycaemia-induced acceleration of atherosclerosis in a diabetic pig model Diabetologia 45 2002 125 133
    • (2002) Diabetologia , vol.45 , pp. 125-133
    • Natarajan, R.1    Gerrity, R.G.2    Gu, J.L.3    Lanting, L.4    Thomas, L.5    Nadler, J.L.6
  • 159
    • 33644875634 scopus 로고    scopus 로고
    • Activation of the 12-lipoxygenase and signal transducer and activator of transcription pathway during neointima formation in a model of the metabolic syndrome
    • H. Pei, J. Gu, P.R. Thimmalapura, A. Mison, and J.L. Nadler Activation of the 12-lipoxygenase and signal transducer and activator of transcription pathway during neointima formation in a model of the metabolic syndrome Am J Physiol Endocrinol Metab 290 2006 E92 E102
    • (2006) Am J Physiol Endocrinol Metab , vol.290
    • Pei, H.1    Gu, J.2    Thimmalapura, P.R.3    Mison, A.4    Nadler, J.L.5
  • 160
    • 0029006970 scopus 로고
    • Ribozyme-mediated inhibition of expression of leukocyte-type 12-lipoxygenase in porcine aortic vascular smooth muscle cells
    • J.L. Gu, D. Veerapanane, J. Rossi, R. Natarajan, L. Thomas, and J. Nadler Ribozyme-mediated inhibition of expression of leukocyte-type 12-lipoxygenase in porcine aortic vascular smooth muscle cells Circ Res 77 1995 14 20
    • (1995) Circ Res , vol.77 , pp. 14-20
    • Gu, J.L.1    Veerapanane, D.2    Rossi, J.3    Natarajan, R.4    Thomas, L.5    Nadler, J.6
  • 161
    • 0038640370 scopus 로고    scopus 로고
    • Overexpression of 12-lipoxygenase and cardiac fibroblast hypertrophy
    • Y. Wen, J. Gu, X. Peng, G. Zhang, and J. Nadler Overexpression of 12-lipoxygenase and cardiac fibroblast hypertrophy Trends Cardiovasc Med 13 2003 129 136
    • (2003) Trends Cardiovasc Med , vol.13 , pp. 129-136
    • Wen, Y.1    Gu, J.2    Peng, X.3    Zhang, G.4    Nadler, J.5
  • 162
    • 0024329942 scopus 로고
    • Lipoxin A4 and lipoxin B4 inhibit chemotactic responses of human neutrophils stimulated by leukotriene B4 and N-formyl-l-methionyl-l-leucyl-l- phenylalanine
    • T.H. Lee, C.E. Horton, U. Kyan-Aung, D. Haskard, A.E. Crea, and B.W. Spur Lipoxin A4 and lipoxin B4 inhibit chemotactic responses of human neutrophils stimulated by leukotriene B4 and N-formyl-l-methionyl-l-leucyl-l-phenylalanine Clin Sci (Lond) 77 1989 195 203
    • (1989) Clin Sci (Lond) , vol.77 , pp. 195-203
    • Lee, T.H.1    Horton, C.E.2    Kyan-Aung, U.3    Haskard, D.4    Crea, A.E.5    Spur, B.W.6
  • 163
    • 0027337719 scopus 로고
    • Lipoxin A4 modulates transmigration of human neutrophils across intestinal epithelial monolayers
    • S.P. Colgan, C.N. Serhan, C.A. Parkos, C. Delp-Archer, and J.L. Madara Lipoxin A4 modulates transmigration of human neutrophils across intestinal epithelial monolayers J Clin Invest 92 1993 75 82
    • (1993) J Clin Invest , vol.92 , pp. 75-82
    • Colgan, S.P.1    Serhan, C.N.2    Parkos, C.A.3    Delp-Archer, C.4    Madara, J.L.5
  • 164
    • 0034651737 scopus 로고    scopus 로고
    • Cutting edge: Lipoxins rapidly stimulate nonphlogistic phagocytosis of apoptotic neutrophils by monocyte-derived macrophages
    • C. Godson, S. Mitchell, K. Harvey, N.A. Petasis, N. Hogg, and H.R. Brady Cutting edge: lipoxins rapidly stimulate nonphlogistic phagocytosis of apoptotic neutrophils by monocyte-derived macrophages J Immunol 164 2000 1663 1667
    • (2000) J Immunol , vol.164 , pp. 1663-1667
    • Godson, C.1    Mitchell, S.2    Harvey, K.3    Petasis, N.A.4    Hogg, N.5    Brady, H.R.6
  • 165
    • 0029671266 scopus 로고    scopus 로고
    • Lipoxin A4 and B4 are potent stimuli for human monocyte migration and adhesion: Selective inactivation by dehydrogenation and reduction
    • J.F. Maddox, and C.N. Serhan Lipoxin A4 and B4 are potent stimuli for human monocyte migration and adhesion: selective inactivation by dehydrogenation and reduction J Exp Med 183 1996 137 146
    • (1996) J Exp Med , vol.183 , pp. 137-146
    • Maddox, J.F.1    Serhan, C.N.2
  • 166
  • 167
    • 18544378668 scopus 로고    scopus 로고
    • Lipoxins, aspirin-triggered epi-lipoxins, lipoxin stable analogues, and the resolution of inflammation: Stimulation of macrophage phagocytosis of apoptotic neutrophils in vivo
    • S. Mitchell, G. Thomas, K. Harvey, D. Cottell, K. Reville, and G. Berlasconi Lipoxins, aspirin-triggered epi-lipoxins, lipoxin stable analogues, and the resolution of inflammation: stimulation of macrophage phagocytosis of apoptotic neutrophils in vivo J Am Soc Nephrol 13 2002 2497 2507
    • (2002) J Am Soc Nephrol , vol.13 , pp. 2497-2507
    • Mitchell, S.1    Thomas, G.2    Harvey, K.3    Cottell, D.4    Reville, K.5    Berlasconi, G.6
  • 168
    • 54049137639 scopus 로고    scopus 로고
    • Atherosclerosis: Evidence for impairment of resolution of vascular inflammation governed by specific lipid mediators
    • A.J. Merched, K. Ko, K.H. Gotlinger, C.N. Serhan, and L. Chan Atherosclerosis: evidence for impairment of resolution of vascular inflammation governed by specific lipid mediators Faseb J 22 2008 3595 3606
    • (2008) Faseb J , vol.22 , pp. 3595-3606
    • Merched, A.J.1    Ko, K.2    Gotlinger, K.H.3    Serhan, C.N.4    Chan, L.5
  • 169
    • 33947269798 scopus 로고    scopus 로고
    • Resolvin E1 selectively interacts with leukotriene B4 receptor BLT1 and ChemR23 to regulate inflammation
    • M. Arita, T. Ohira, Y.P. Sun, S. Elangovan, N. Chiang, and C.N. Serhan Resolvin E1 selectively interacts with leukotriene B4 receptor BLT1 and ChemR23 to regulate inflammation J Immunol 178 2007 3912 3917
    • (2007) J Immunol , vol.178 , pp. 3912-3917
    • Arita, M.1    Ohira, T.2    Sun, Y.P.3    Elangovan, S.4    Chiang, N.5    Serhan, C.N.6
  • 171
    • 0025897282 scopus 로고
    • Gene expression in macrophage-rich human atherosclerotic lesions. 15-lipoxygenase and acetyl low density lipoprotein receptor messenger RNA colocalize with oxidation specific lipid-protein adducts
    • S. Yla-Herttuala, M.E. Rosenfeld, S. Parthasarathy, E. Sigal, T. Sarkioja, and J.L. Witztum Gene expression in macrophage-rich human atherosclerotic lesions. 15-lipoxygenase and acetyl low density lipoprotein receptor messenger RNA colocalize with oxidation specific lipid-protein adducts J Clin Invest 87 1991 1146 1152
    • (1991) J Clin Invest , vol.87 , pp. 1146-1152
    • Yla-Herttuala, S.1    Rosenfeld, M.E.2    Parthasarathy, S.3    Sigal, E.4    Sarkioja, T.5    Witztum, J.L.6
  • 172
    • 0344145871 scopus 로고    scopus 로고
    • In vivo action of 15-lipoxygenase in early stages of human atherogenesis
    • H. Kuhn, D. Heydeck, I. Hugou, and C. Gniwotta In vivo action of 15-lipoxygenase in early stages of human atherogenesis J Clin Invest 99 1997 888 893
    • (1997) J Clin Invest , vol.99 , pp. 888-893
    • Kuhn, H.1    Heydeck, D.2    Hugou, I.3    Gniwotta, C.4
  • 173
    • 74049111313 scopus 로고    scopus 로고
    • 15-Lipoxygenase-2 is expressed in macrophages in human carotid plaques and regulated by hypoxia-inducible factor-1alpha
    • L.M. Hulten, F.J. Olson, H. Aberg, J. Carlsson, L. Karlstrom, and J. Boren 15-Lipoxygenase-2 is expressed in macrophages in human carotid plaques and regulated by hypoxia-inducible factor-1alpha Eur J Clin Invest 40 2010 11 17
    • (2010) Eur J Clin Invest , vol.40 , pp. 11-17
    • Hulten, L.M.1    Olson, F.J.2    Aberg, H.3    Carlsson, J.4    Karlstrom, L.5    Boren, J.6
  • 174
    • 34247357016 scopus 로고    scopus 로고
    • The c.-292C>T promoter polymorphism increases reticulocyte-type 15-lipoxygenase-1 activity and could be atheroprotective
    • J. Wittwer, M. Bayer, A. Mosandl, J. Muntwyler, and M. Hersberger The c.-292C>T promoter polymorphism increases reticulocyte-type 15-lipoxygenase-1 activity and could be atheroprotective Clin Chem Lab Med 45 2007 487 492
    • (2007) Clin Chem Lab Med , vol.45 , pp. 487-492
    • Wittwer, J.1    Bayer, M.2    Mosandl, A.3    Muntwyler, J.4    Hersberger, M.5
  • 175
    • 40949164339 scopus 로고    scopus 로고
    • A near null variant of 12/15-LOX encoded by a novel SNP in ALOX15 and the risk of coronary artery disease
    • T.L. Assimes, J.W. Knowles, J.R. Priest, A. Basu, A. Borchert, and K.A. Volcik A near null variant of 12/15-LOX encoded by a novel SNP in ALOX15 and the risk of coronary artery disease Atherosclerosis 198 2008 136 144
    • (2008) Atherosclerosis , vol.198 , pp. 136-144
    • Assimes, T.L.1    Knowles, J.W.2    Priest, J.R.3    Basu, A.4    Borchert, A.5    Volcik, K.A.6
  • 176
    • 77953519631 scopus 로고    scopus 로고
    • Human lipoxygenase pathway gene variation and association with markers of subclinical atherosclerosis in the diabetes heart study
    • K.P. Burdon, M.E. Rudock, A.B. Lehtinen, C.D. Langefeld, D.W. Bowden, and T.C. Register Human lipoxygenase pathway gene variation and association with markers of subclinical atherosclerosis in the diabetes heart study Mediators Inflamm 2010 2010 170153
    • (2010) Mediators Inflamm , vol.2010 , pp. 170153
    • Burdon, K.P.1    Rudock, M.E.2    Lehtinen, A.B.3    Langefeld, C.D.4    Bowden, D.W.5    Register, T.C.6
  • 177
    • 0035164723 scopus 로고    scopus 로고
    • Overexpression of 15-lipoxygenase-1 in PC-3 human prostate cancer cells increases tumorigenesis
    • U.P. Kelavkar, J.B. Nixon, C. Cohen, D. Dillehay, T.E. Eling, and K.F. Badr Overexpression of 15-lipoxygenase-1 in PC-3 human prostate cancer cells increases tumorigenesis Carcinogenesis 22 2001 1765 1773
    • (2001) Carcinogenesis , vol.22 , pp. 1765-1773
    • Kelavkar, U.P.1    Nixon, J.B.2    Cohen, C.3    Dillehay, D.4    Eling, T.E.5    Badr, K.F.6
  • 178
    • 41149111018 scopus 로고    scopus 로고
    • 15-lipoxygenase-1 prevents vascular endothelial growth factor A- and placental growth factor-induced angiogenic effects in rabbit skeletal muscles via reduction in growth factor mRNA levels, NO bioactivity, and downregulation of VEGF receptor 2 expression
    • H. Viita, J. Markkanen, E. Eriksson, M. Nurminen, K. Kinnunen, and M. Babu 15-lipoxygenase-1 prevents vascular endothelial growth factor A- and placental growth factor-induced angiogenic effects in rabbit skeletal muscles via reduction in growth factor mRNA levels, NO bioactivity, and downregulation of VEGF receptor 2 expression Circ Res 102 2008 177 184
    • (2008) Circ Res , vol.102 , pp. 177-184
    • Viita, H.1    Markkanen, J.2    Eriksson, E.3    Nurminen, M.4    Kinnunen, K.5    Babu, M.6
  • 179
    • 24344504411 scopus 로고    scopus 로고
    • Inhibition of carcinogenesis in transgenic mouse models over-expressing 15-lipoxygenase in the vascular wall under the control of murine preproendothelin-1 promoter
    • D. Harats, D. Ben-Shushan, H. Cohen, A. Gonen, I. Barshack, and I. Goldberg Inhibition of carcinogenesis in transgenic mouse models over-expressing 15-lipoxygenase in the vascular wall under the control of murine preproendothelin-1 promoter Cancer Lett 229 2005 127 134
    • (2005) Cancer Lett , vol.229 , pp. 127-134
    • Harats, D.1    Ben-Shushan, D.2    Cohen, H.3    Gonen, A.4    Barshack, I.5    Goldberg, I.6
  • 180
    • 74549130049 scopus 로고    scopus 로고
    • Intravitreal adenoviral 15-lipoxygenase-1 gene transfer prevents vascular endothelial growth factor A-induced neovascularization in rabbit eyes
    • H. Viita, K. Kinnunen, E. Eriksson, J. Lahteenvuo, M. Babu, and G. Kalesnykas Intravitreal adenoviral 15-lipoxygenase-1 gene transfer prevents vascular endothelial growth factor A-induced neovascularization in rabbit eyes Hum Gene Ther 20 2009 1679 1686
    • (2009) Hum Gene Ther , vol.20 , pp. 1679-1686
    • Viita, H.1    Kinnunen, K.2    Eriksson, E.3    Lahteenvuo, J.4    Babu, M.5    Kalesnykas, G.6
  • 181
    • 77949621085 scopus 로고    scopus 로고
    • Absence of glutathione peroxidase 4 affects tumor angiogenesis through increased 12/15-lipoxygenase activity
    • M. Schneider, M. Wortmann, P.K. Mandal, W. Arpornchayanon, K. Jannasch, and F. Alves Absence of glutathione peroxidase 4 affects tumor angiogenesis through increased 12/15-lipoxygenase activity Neoplasia 12 2010 254 263
    • (2010) Neoplasia , vol.12 , pp. 254-263
    • Schneider, M.1    Wortmann, M.2    Mandal, P.K.3    Arpornchayanon, W.4    Jannasch, K.5    Alves, F.6
  • 182
    • 77953230908 scopus 로고    scopus 로고
    • 12-Lipoxygenase and the regulation of hypoxia-inducible factor in prostate cancer cells
    • S. Krishnamoorthy, R. Jin, Y. Cai, K.R. Maddipati, D. Nie, and G. Pages 12-Lipoxygenase and the regulation of hypoxia-inducible factor in prostate cancer cells Exp Cell Res 316 2010 1706 1715
    • (2010) Exp Cell Res , vol.316 , pp. 1706-1715
    • Krishnamoorthy, S.1    Jin, R.2    Cai, Y.3    Maddipati, K.R.4    Nie, D.5    Pages, G.6
  • 183
    • 77950398950 scopus 로고    scopus 로고
    • 15(S)-hydroxyeicosatetraenoic acid-induced angiogenesis requires Src-mediated Egr-1-dependent rapid induction of FGF-2 expression
    • V. Kundumani-Sridharan, J. Niu, D. Wang, D. Van Quyen, Q. Zhang, and N.K. Singh 15(S)-hydroxyeicosatetraenoic acid-induced angiogenesis requires Src-mediated Egr-1-dependent rapid induction of FGF-2 expression Blood 115 2010 2105 2116
    • (2010) Blood , vol.115 , pp. 2105-2116
    • Kundumani-Sridharan, V.1    Niu, J.2    Wang, D.3    Van Quyen, D.4    Zhang, Q.5    Singh, N.K.6
  • 184
    • 73949160807 scopus 로고    scopus 로고
    • Endogenous LXA4 circuits are determinants of pathological angiogenesis in response to chronic injury
    • A.J. Leedom, A.B. Sullivan, B. Dong, D. Lau, and K. Gronert Endogenous LXA4 circuits are determinants of pathological angiogenesis in response to chronic injury Am J Pathol 176 2010 74 84
    • (2010) Am J Pathol , vol.176 , pp. 74-84
    • Leedom, A.J.1    Sullivan, A.B.2    Dong, B.3    Lau, D.4    Gronert, K.5
  • 185
    • 33745797993 scopus 로고    scopus 로고
    • Eicosanoids and renal vascular function in diseases
    • J.D. Imig Eicosanoids and renal vascular function in diseases Clin Sci (Lond) 111 2006 21 34
    • (2006) Clin Sci (Lond) , vol.111 , pp. 21-34
    • Imig, J.D.1
  • 186
    • 34249110684 scopus 로고    scopus 로고
    • Roles of lipid mediators in kidney injury
    • C.M. Hao, and M.D. Breyer Roles of lipid mediators in kidney injury Semin Nephrol 27 2007 338 351
    • (2007) Semin Nephrol , vol.27 , pp. 338-351
    • Hao, C.M.1    Breyer, M.D.2
  • 187
    • 34249287061 scopus 로고    scopus 로고
    • Physiologic and pathophysiologic roles of lipid mediators in the kidney
    • C.M. Hao, and M.D. Breyer Physiologic and pathophysiologic roles of lipid mediators in the kidney Kidney Int 71 2007 1105 1115
    • (2007) Kidney Int , vol.71 , pp. 1105-1115
    • Hao, C.M.1    Breyer, M.D.2
  • 188
    • 0347093588 scopus 로고    scopus 로고
    • 12-Hydroxyeicosatetraenoic acid participates in angiotensin II afferent arteriolar vasoconstriction by activating L-type calcium channels
    • S.S. Yiu, X. Zhao, E.W. Inscho, and J.D. Imig 12-Hydroxyeicosatetraenoic acid participates in angiotensin II afferent arteriolar vasoconstriction by activating L-type calcium channels J Lipid Res 44 2003 2391 2399
    • (2003) J Lipid Res , vol.44 , pp. 2391-2399
    • Yiu, S.S.1    Zhao, X.2    Inscho, E.W.3    Imig, J.D.4
  • 189
    • 0026699147 scopus 로고
    • Renal hemodynamic actions of lipoxins in rats: A comparative physiological study
    • T. Katoh, K. Takahashi, D.K. DeBoer, C.N. Serhan, and K.F. Badr Renal hemodynamic actions of lipoxins in rats: a comparative physiological study Am J Physiol 263 1992 F436 F442
    • (1992) Am J Physiol , vol.263
    • Katoh, T.1    Takahashi, K.2    Deboer, D.K.3    Serhan, C.N.4    Badr, K.F.5
  • 190
    • 0026693218 scopus 로고
    • 12-Lipoxygenase products modulate calcium signals in vascular smooth muscle cells
    • F. Saito, M.T. Hori, Y. Ideguchi, M. Berger, M. Golub, and N. Stern 12-Lipoxygenase products modulate calcium signals in vascular smooth muscle cells Hypertension 20 1992 138 143
    • (1992) Hypertension , vol.20 , pp. 138-143
    • Saito, F.1    Hori, M.T.2    Ideguchi, Y.3    Berger, M.4    Golub, M.5    Stern, N.6
  • 191
    • 67651085473 scopus 로고    scopus 로고
    • Angiotensin II type 1 receptor expression is increased via 12-lipoxygenase in high glucose-stimulated glomerular cells and type 2 diabetic glomeruli
    • Z.G. Xu, L.N. Miao, Y.C. Cui, Y. Jia, H. Yuan, and M. Wu Angiotensin II type 1 receptor expression is increased via 12-lipoxygenase in high glucose-stimulated glomerular cells and type 2 diabetic glomeruli Nephrol Dial Transplant 24 2009 1744 1752
    • (2009) Nephrol Dial Transplant , vol.24 , pp. 1744-1752
    • Xu, Z.G.1    Miao, L.N.2    Cui, Y.C.3    Jia, Y.4    Yuan, H.5    Wu, M.6
  • 192
    • 0035210544 scopus 로고    scopus 로고
    • Interactions of nitric oxide-derived reactive nitrogen species with peroxidases and lipoxygenases
    • M.J. Coffey, B. Coles, and V.B. O'Donnell Interactions of nitric oxide-derived reactive nitrogen species with peroxidases and lipoxygenases Free Radic Res 35 2001 447 464
    • (2001) Free Radic Res , vol.35 , pp. 447-464
    • Coffey, M.J.1    Coles, B.2    O'Donnell, V.B.3
  • 194
    • 0023473551 scopus 로고
    • Specific action of the lipoxygenase pathway in mediating angiotensin II-induced aldosterone synthesis in isolated adrenal glomerulosa cells
    • J.L. Nadler, R. Natarajan, and N. Stern Specific action of the lipoxygenase pathway in mediating angiotensin II-induced aldosterone synthesis in isolated adrenal glomerulosa cells J Clin Invest 80 1987 1763 1769
    • (1987) J Clin Invest , vol.80 , pp. 1763-1769
    • Nadler, J.L.1    Natarajan, R.2    Stern, N.3
  • 195
    • 72449191387 scopus 로고    scopus 로고
    • Aldosterone up-regulates 12- and 15-lipoxygenase expression and LDL oxidation in human vascular smooth muscle cells
    • R. Limor, M. Kaplan, O. Sharon, E. Knoll, M. Naidich, and G. Weisinger Aldosterone up-regulates 12- and 15-lipoxygenase expression and LDL oxidation in human vascular smooth muscle cells J Cell Biochem 108 2009 1203 1210
    • (2009) J Cell Biochem , vol.108 , pp. 1203-1210
    • Limor, R.1    Kaplan, M.2    Sharon, O.3    Knoll, E.4    Naidich, M.5    Weisinger, G.6
  • 196
    • 0035092916 scopus 로고    scopus 로고
    • Increased levels of 12(S)-HETE in patients with essential hypertension
    • D. Gonzalez-Nunez, J. Claria, F. Rivera, and E. Poch Increased levels of 12(S)-HETE in patients with essential hypertension Hypertension 37 2001 334 338
    • (2001) Hypertension , vol.37 , pp. 334-338
    • Gonzalez-Nunez, D.1    Claria, J.2    Rivera, F.3    Poch, E.4
  • 197
    • 31544454435 scopus 로고    scopus 로고
    • A coding polymorphism in the 12-lipoxygenase gene is associated to essential hypertension and urinary 12(S)-HETE
    • L.F. Quintana, B. Guzman, S. Collado, J. Claria, and E. Poch A coding polymorphism in the 12-lipoxygenase gene is associated to essential hypertension and urinary 12(S)-HETE Kidney Int 69 2006 526 530
    • (2006) Kidney Int , vol.69 , pp. 526-530
    • Quintana, L.F.1    Guzman, B.2    Collado, S.3    Claria, J.4    Poch, E.5
  • 198
    • 0022412370 scopus 로고
    • Increase in 12-lipoxygenase activity in platelets of spontaneously hypertensive rats
    • W.C. Chang, and G.W. Su Increase in 12-lipoxygenase activity in platelets of spontaneously hypertensive rats Biochem Biophys Res Commun 127 1985 642 648
    • (1985) Biochem Biophys Res Commun , vol.127 , pp. 642-648
    • Chang, W.C.1    Su, G.W.2
  • 199
    • 0031002609 scopus 로고    scopus 로고
    • Elevated 12-lipoxygenase activity in the spontaneously hypertensive rat
    • M. Sasaki, M.T. Hori, T. Hino, M.S. Golub, and M.L. Tuck Elevated 12-lipoxygenase activity in the spontaneously hypertensive rat Am J Hypertens 10 1997 371 378
    • (1997) Am J Hypertens , vol.10 , pp. 371-378
    • Sasaki, M.1    Hori, M.T.2    Hino, T.3    Golub, M.S.4    Tuck, M.L.5
  • 200
    • 0025643542 scopus 로고
    • Inhibition of lipoxygenase pathway reduces blood pressure in renovascular hypertensive rats
    • K. Nozawa, M.L. Tuck, M. Golub, P. Eggena, J.L. Nadler, and N. Stern Inhibition of lipoxygenase pathway reduces blood pressure in renovascular hypertensive rats Am J Physiol 259 1990 H1774 H1780
    • (1990) Am J Physiol , vol.259
    • Nozawa, K.1    Tuck, M.L.2    Golub, M.3    Eggena, P.4    Nadler, J.L.5    Stern, N.6
  • 202
    • 10944228040 scopus 로고    scopus 로고
    • 12-Lipoxygenase metabolism in mouse distal convoluted tubule cells
    • D. Gonzalez-Nunez, M. Sole, R. Natarajan, and E. Poch 12-Lipoxygenase metabolism in mouse distal convoluted tubule cells Kidney Int 67 2005 178 186
    • (2005) Kidney Int , vol.67 , pp. 178-186
    • Gonzalez-Nunez, D.1    Sole, M.2    Natarajan, R.3    Poch, E.4
  • 203
    • 31544433994 scopus 로고    scopus 로고
    • Relationship between 12/15-lipoxygenase and COX-2 in mesangial cells: Potential role in diabetic nephropathy
    • Z.G. Xu, S.L. Li, L. Lanting, Y.S. Kim, N. Shanmugam, and M.A. Reddy Relationship between 12/15-lipoxygenase and COX-2 in mesangial cells: potential role in diabetic nephropathy Kidney Int 69 2006 512 519
    • (2006) Kidney Int , vol.69 , pp. 512-519
    • Xu, Z.G.1    Li, S.L.2    Lanting, L.3    Kim, Y.S.4    Shanmugam, N.5    Reddy, M.A.6
  • 204
    • 0344667756 scopus 로고    scopus 로고
    • Role of 12-lipoxygenase in the stimulation of p38 mitogen-activated protein kinase and collagen alpha5(IV) in experimental diabetic nephropathy and in glucose-stimulated podocytes
    • S.W. Kang, R. Natarajan, A. Shahed, C.C. Nast, J. LaPage, and P. Mundel Role of 12-lipoxygenase in the stimulation of p38 mitogen-activated protein kinase and collagen alpha5(IV) in experimental diabetic nephropathy and in glucose-stimulated podocytes J Am Soc Nephrol 14 2003 3178 3187
    • (2003) J Am Soc Nephrol , vol.14 , pp. 3178-3187
    • Kang, S.W.1    Natarajan, R.2    Shahed, A.3    Nast, C.C.4    Lapage, J.5    Mundel, P.6
  • 205
    • 0035071318 scopus 로고    scopus 로고
    • 12-lipoxygenase is increased in glucose-stimulated mesangial cells and in experimental diabetic nephropathy
    • S.W. Kang, S.G. Adler, C.C. Nast, J. LaPage, J.L. Gu, and J.L. Nadler 12-lipoxygenase is increased in glucose-stimulated mesangial cells and in experimental diabetic nephropathy Kidney Int 59 2001 1354 1362
    • (2001) Kidney Int , vol.59 , pp. 1354-1362
    • Kang, S.W.1    Adler, S.G.2    Nast, C.C.3    Lapage, J.4    Gu, J.L.5    Nadler, J.L.6
  • 206
    • 0029880924 scopus 로고    scopus 로고
    • A 12-lipoxygenase product, 12-hydroxyeicosatetraenoic acid, is increased in diabetics with incipient and early renal disease
    • I. Antonipillai, J. Nadler, E.J. Vu, S. Bughi, R. Natarajan, and R. Horton A 12-lipoxygenase product, 12-hydroxyeicosatetraenoic acid, is increased in diabetics with incipient and early renal disease J Clin Endocrinol Metab 81 1996 1940 1945
    • (1996) J Clin Endocrinol Metab , vol.81 , pp. 1940-1945
    • Antonipillai, I.1    Nadler, J.2    Vu, E.J.3    Bughi, S.4    Natarajan, R.5    Horton, R.6
  • 208
    • 20544459331 scopus 로고    scopus 로고
    • Novel interactions between TGF-{beta}1 actions and the 12/15-lipoxygenase pathway in mesangial cells
    • Y.S. Kim, Z.G. Xu, M.A. Reddy, S.L. Li, L. Lanting, and K. Sharma Novel interactions between TGF-{beta}1 actions and the 12/15-lipoxygenase pathway in mesangial cells J Am Soc Nephrol 16 2005 352 362
    • (2005) J Am Soc Nephrol , vol.16 , pp. 352-362
    • Kim, Y.S.1    Xu, Z.G.2    Reddy, M.A.3    Li, S.L.4    Lanting, L.5    Sharma, K.6
  • 209
    • 0142218424 scopus 로고    scopus 로고
    • Differential behavior of mesangial cells derived from 12/15-lipoxygenase knockout mice relative to control mice
    • Y.S. Kim, M.A. Reddy, L. Lanting, S.G. Adler, and R. Natarajan Differential behavior of mesangial cells derived from 12/15-lipoxygenase knockout mice relative to control mice Kidney Int 64 2003 1702 1714
    • (2003) Kidney Int , vol.64 , pp. 1702-1714
    • Kim, Y.S.1    Reddy, M.A.2    Lanting, L.3    Adler, S.G.4    Natarajan, R.5
  • 210
    • 0942301316 scopus 로고    scopus 로고
    • Lipoxins: Endogenous regulators of inflammation
    • B. McMahon, and C. Godson Lipoxins: endogenous regulators of inflammation Am J Physiol Renal Physiol 286 2004 F189 F201
    • (2004) Am J Physiol Renal Physiol , vol.286
    • McMahon, B.1    Godson, C.2
  • 211
    • 1642422412 scopus 로고    scopus 로고
    • Lipoxins: Potential anti-inflammatory, proresolution, and antifibrotic mediators in renal disease
    • N.E. Kieran, P. Maderna, and C. Godson Lipoxins: potential anti-inflammatory, proresolution, and antifibrotic mediators in renal disease Kidney Int 65 2004 1145 1154
    • (2004) Kidney Int , vol.65 , pp. 1145-1154
    • Kieran, N.E.1    Maderna, P.2    Godson, C.3
  • 212
    • 0029670175 scopus 로고    scopus 로고
    • Lipoxin A4 and B4 inhibit leukotriene-stimulated interactions of human neutrophils and endothelial cells
    • A. Papayianni, C.N. Serhan, and H.R. Brady Lipoxin A4 and B4 inhibit leukotriene-stimulated interactions of human neutrophils and endothelial cells J Immunol 156 1996 2264 2272
    • (1996) J Immunol , vol.156 , pp. 2264-2272
    • Papayianni, A.1    Serhan, C.N.2    Brady, H.R.3
  • 213
    • 0036831229 scopus 로고    scopus 로고
    • Lipoxin, leukotriene, and PDGF receptors cross-talk to regulate mesangial cell proliferation
    • B. McMahon, D. Mitchell, R. Shattock, F. Martin, H.R. Brady, and C. Godson Lipoxin, leukotriene, and PDGF receptors cross-talk to regulate mesangial cell proliferation Faseb J 16 2002 1817 1819
    • (2002) Faseb J , vol.16 , pp. 1817-1819
    • McMahon, B.1    Mitchell, D.2    Shattock, R.3    Martin, F.4    Brady, H.R.5    Godson, C.6
  • 214
    • 0034622672 scopus 로고    scopus 로고
    • Lipoxin A4 antagonizes the mitogenic effects of leukotriene D4 in human renal mesangial cells. Differential activation of MAP kinases through distinct receptors
    • B. McMahon, C. Stenson, F. McPhillips, A. Fanning, H.R. Brady, and C. Godson Lipoxin A4 antagonizes the mitogenic effects of leukotriene D4 in human renal mesangial cells. Differential activation of MAP kinases through distinct receptors J Biol Chem 275 2000 27566 27575
    • (2000) J Biol Chem , vol.275 , pp. 27566-27575
    • McMahon, B.1    Stenson, C.2    McPhillips, F.3    Fanning, A.4    Brady, H.R.5    Godson, C.6
  • 215
    • 10744230052 scopus 로고    scopus 로고
    • Modification of the transcriptomic response to renal ischemia/reperfusion injury by lipoxin analog
    • N.E. Kieran, P.P. Doran, S.B. Connolly, M.C. Greenan, D.F. Higgins, and M. Leonard Modification of the transcriptomic response to renal ischemia/reperfusion injury by lipoxin analog Kidney Int 64 2003 480 492
    • (2003) Kidney Int , vol.64 , pp. 480-492
    • Kieran, N.E.1    Doran, P.P.2    Connolly, S.B.3    Greenan, M.C.4    Higgins, D.F.5    Leonard, M.6
  • 216
    • 0033539695 scopus 로고    scopus 로고
    • Transfection of rat kidney with human 15-lipoxygenase suppresses inflammation and preserves function in experimental glomerulonephritis
    • K.A. Munger, A. Montero, M. Fukunaga, S. Uda, T. Yura, and E. Imai Transfection of rat kidney with human 15-lipoxygenase suppresses inflammation and preserves function in experimental glomerulonephritis Proc Natl Acad Sci USA 96 1999 13375 13380
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 13375-13380
    • Munger, K.A.1    Montero, A.2    Fukunaga, M.3    Uda, S.4    Yura, T.5    Imai, E.6
  • 217
    • 0036014949 scopus 로고    scopus 로고
    • 15-Epi-16-(para-fluorophenoxy)-lipoxin A(4)-methyl ester, a synthetic analogue of 15-epi-lipoxin A(4), is protective in experimental ischemic acute renal failure
    • M.O. Leonard, K. Hannan, M.J. Burne, D.W. Lappin, P. Doran, and P. Coleman 15-Epi-16-(para-fluorophenoxy)-lipoxin A(4)-methyl ester, a synthetic analogue of 15-epi-lipoxin A(4), is protective in experimental ischemic acute renal failure J Am Soc Nephrol 13 2002 1657 1662
    • (2002) J Am Soc Nephrol , vol.13 , pp. 1657-1662
    • Leonard, M.O.1    Hannan, K.2    Burne, M.J.3    Lappin, D.W.4    Doran, P.5    Coleman, P.6
  • 218
    • 64849091646 scopus 로고    scopus 로고
    • Acute changes in dietary omega-3 and omega-6 polyunsaturated fatty acids have a pronounced impact on survival following ischemic renal injury and formation of renoprotective docosahexaenoic acid-derived protectin D1
    • I.R. Hassan, and K. Gronert Acute changes in dietary omega-3 and omega-6 polyunsaturated fatty acids have a pronounced impact on survival following ischemic renal injury and formation of renoprotective docosahexaenoic acid-derived protectin D1 J Immunol 182 2009 3223 3232
    • (2009) J Immunol , vol.182 , pp. 3223-3232
    • Hassan, I.R.1    Gronert, K.2
  • 219
    • 0032845121 scopus 로고    scopus 로고
    • Ischemic cell death in brain neurons
    • P. Lipton Ischemic cell death in brain neurons Physiol Rev 79 1999 1431 1568
    • (1999) Physiol Rev , vol.79 , pp. 1431-1568
    • Lipton, P.1
  • 220
    • 0024353224 scopus 로고
    • Effect of cyclooxygenase and lipoxygenase inhibitors on delayed neuronal death in the gerbil hippocampus
    • T. Nakagomi, T. Sasaki, T. Kirino, A. Tamura, M. Noguchi, and I. Saito Effect of cyclooxygenase and lipoxygenase inhibitors on delayed neuronal death in the gerbil hippocampus Stroke 20 1989 925 929
    • (1989) Stroke , vol.20 , pp. 925-929
    • Nakagomi, T.1    Sasaki, T.2    Kirino, T.3    Tamura, A.4    Noguchi, M.5    Saito, I.6
  • 221
    • 33845442015 scopus 로고    scopus 로고
    • Baicalein and 12/15-lipoxygenase in the ischemic brain
    • K. van Leyen, H.Y. Kim, S.R. Lee, G. Jin, K. Arai, and E.H. Lo Baicalein and 12/15-lipoxygenase in the ischemic brain Stroke 37 2006 3014 3018
    • (2006) Stroke , vol.37 , pp. 3014-3018
    • Van Leyen, K.1    Kim, H.Y.2    Lee, S.R.3    Jin, G.4    Arai, K.5    Lo, E.H.6
  • 222
    • 36749068009 scopus 로고    scopus 로고
    • Baicalein, an antioxidant 12/15-lipoxygenase inhibitor improves clinical rating scores following multiple infarct embolic strokes
    • P.A. Lapchak, P. Maher, D. Schubert, and J.A. Zivin Baicalein, an antioxidant 12/15-lipoxygenase inhibitor improves clinical rating scores following multiple infarct embolic strokes Neuroscience 150 2007 585 591
    • (2007) Neuroscience , vol.150 , pp. 585-591
    • Lapchak, P.A.1    Maher, P.2    Schubert, D.3    Zivin, J.A.4
  • 223
    • 9344268817 scopus 로고    scopus 로고
    • Peroxynitrite-induced neuronal apoptosis is mediated by intracellular zinc release and 12-lipoxygenase activation
    • Y. Zhang, H. Wang, J. Li, D.A. Jimenez, E.S. Levitan, and E. Aizenman Peroxynitrite-induced neuronal apoptosis is mediated by intracellular zinc release and 12-lipoxygenase activation J Neurosci 24 2004 10616 10627
    • (2004) J Neurosci , vol.24 , pp. 10616-10627
    • Zhang, Y.1    Wang, H.2    Li, J.3    Jimenez, D.A.4    Levitan, E.S.5    Aizenman, E.6
  • 224
    • 77953139108 scopus 로고    scopus 로고
    • Increased nuclear apoptosis-inducing factor after transient focal ischemia: A 12/15-lipoxygenase-dependent organelle damage pathway
    • S. Pallast, K. Arai, A. Pekcec, K. Yigitkanli, Z. Yu, and X. Wang Increased nuclear apoptosis-inducing factor after transient focal ischemia: a 12/15-lipoxygenase-dependent organelle damage pathway J Cereb Blood Flow Metab 30 2010 1157 1167
    • (2010) J Cereb Blood Flow Metab , vol.30 , pp. 1157-1167
    • Pallast, S.1    Arai, K.2    Pekcec, A.3    Yigitkanli, K.4    Yu, Z.5    Wang, X.6
  • 225
    • 2442621492 scopus 로고    scopus 로고
    • Role of AIF in caspase-dependent and caspase-independent cell death
    • S.P. Cregan, V.L. Dawson, and R.S. Slack Role of AIF in caspase-dependent and caspase-independent cell death Oncogene 23 2004 2785 2796
    • (2004) Oncogene , vol.23 , pp. 2785-2796
    • Cregan, S.P.1    Dawson, V.L.2    Slack, R.S.3
  • 226
    • 52449086378 scopus 로고    scopus 로고
    • Protecting against cerebrovascular injury: Contributions of 12/15-lipoxygenase to edema formation after transient focal ischemia
    • G. Jin, K. Arai, Y. Murata, S. Wang, M.F. Stins, and E.H. Lo Protecting against cerebrovascular injury: contributions of 12/15-lipoxygenase to edema formation after transient focal ischemia Stroke 39 2008 2538 2543
    • (2008) Stroke , vol.39 , pp. 2538-2543
    • Jin, G.1    Arai, K.2    Murata, Y.3    Wang, S.4    Stins, M.F.5    Lo, E.H.6
  • 227
    • 4344620045 scopus 로고    scopus 로고
    • Blockade of 12-lipoxygenase expression protects cortical neurons from apoptosis induced by beta-amyloid peptide
    • A. Lebeau, F. Terro, W. Rostene, and D. Pelaprat Blockade of 12-lipoxygenase expression protects cortical neurons from apoptosis induced by beta-amyloid peptide Cell Death Differ 11 2004 875 884
    • (2004) Cell Death Differ , vol.11 , pp. 875-884
    • Lebeau, A.1    Terro, F.2    Rostene, W.3    Pelaprat, D.4
  • 228
    • 25444475777 scopus 로고    scopus 로고
    • Elevation of 12/15 lipoxygenase products in AD and mild cognitive impairment
    • Y. Yao, C.M. Clark, J.Q. Trojanowski, V.M. Lee, and D. Pratico Elevation of 12/15 lipoxygenase products in AD and mild cognitive impairment Ann Neurol 58 2005 623 626
    • (2005) Ann Neurol , vol.58 , pp. 623-626
    • Yao, Y.1    Clark, C.M.2    Trojanowski, J.Q.3    Lee, V.M.4    Pratico, D.5
  • 229
    • 78049423493 scopus 로고    scopus 로고
    • Amelioration of the Alzheimer's disease phenotype by absence of 12/15-lipoxygenase
    • Yang H, Zhuo JM, Chu J, Chinnici C, Pratico D. Amelioration of the Alzheimer's disease phenotype by absence of 12/15-lipoxygenase. Biol Psychiatry, 2010.
    • (2010) Biol Psychiatry
    • Yang, H.1    Zhuo, J.M.2    Chu, J.3    Chinnici, C.4    Pratico, D.5
  • 230
    • 0030867994 scopus 로고    scopus 로고
    • A role for 12-lipoxygenase in nerve cell death caused by glutathione depletion
    • DOI 10.1016/S0896-6273(00)80953-8
    • Y. Li, P. Maher, and D. Schubert A role for 12-lipoxygenase in nerve cell death caused by glutathione depletion Neuron 19 1997 453 463 (Pubitemid 27374242)
    • (1997) Neuron , vol.19 , Issue.2 , pp. 453-463
    • Li, Y.1    Maher, P.2    Schubert, D.3
  • 231
    • 0035664304 scopus 로고    scopus 로고
    • Glutathione depletion switches nitric oxide neurotrophic effects to cell death in midbrain cultures: Implications for Parkinson's disease
    • S. Canals, M.J. Casarejos, S. de Bernardo, E. Rodriguez-Martin, and M.A. Mena Glutathione depletion switches nitric oxide neurotrophic effects to cell death in midbrain cultures: implications for Parkinson's disease J Neurochem 79 2001 1183 1195
    • (2001) J Neurochem , vol.79 , pp. 1183-1195
    • Canals, S.1    Casarejos, M.J.2    De Bernardo, S.3    Rodriguez-Martin, E.4    Mena, M.A.5


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