-
1
-
-
0034221273
-
Human requirement for N-3 polyunsaturated fatty acids
-
A.P. Simopoulos Human requirement for N-3 polyunsaturated fatty acids Poult Sci 79 2000 961 970
-
(2000)
Poult Sci
, vol.79
, pp. 961-970
-
-
Simopoulos, A.P.1
-
3
-
-
0037821818
-
Nitric oxide triggers the toxicity due to glutathione depletion in midbrain cultures through 12-lipoxygenase
-
S. Canals, M.J. Casarejos, S. de Bernardo, E. Rodriguez-Martin, and M.A. Mena Nitric oxide triggers the toxicity due to glutathione depletion in midbrain cultures through 12-lipoxygenase J Biol Chem 278 2003 21542 21549
-
(2003)
J Biol Chem
, vol.278
, pp. 21542-21549
-
-
Canals, S.1
Casarejos, M.J.2
De Bernardo, S.3
Rodriguez-Martin, E.4
Mena, M.A.5
-
4
-
-
1942501585
-
12/15-lipoxygenase is increased in Alzheimer's disease: Possible involvement in brain oxidative stress
-
D. Pratico, V. Zhukareva, Y. Yao, K. Uryu, C.D. Funk, and J.A. Lawson 12/15-lipoxygenase is increased in Alzheimer's disease: possible involvement in brain oxidative stress Am J Pathol 164 2004 1655 1662
-
(2004)
Am J Pathol
, vol.164
, pp. 1655-1662
-
-
Pratico, D.1
Zhukareva, V.2
Yao, Y.3
Uryu, K.4
Funk, C.D.5
Lawson, J.A.6
-
5
-
-
49449090767
-
Biochemistry and physiology of mammalian secreted phospholipases A2
-
G. Lambeau, and M.H. Gelb Biochemistry and physiology of mammalian secreted phospholipases A2 Ann Rev Biochem 77 2008 495 520
-
(2008)
Ann Rev Biochem
, vol.77
, pp. 495-520
-
-
Lambeau, G.1
Gelb, M.H.2
-
6
-
-
4444350561
-
Lipid inflammatory mediators in diabetic vascular disease
-
R. Natarajan, and J.L. Nadler Lipid inflammatory mediators in diabetic vascular disease Arterioscler Thromb Vasc Biol 24 2004 1542 1548
-
(2004)
Arterioscler Thromb Vasc Biol
, vol.24
, pp. 1542-1548
-
-
Natarajan, R.1
Nadler, J.L.2
-
7
-
-
0033588022
-
Lipoxygenases: Occurrence, functions, catalysis, and acquisition of substrate
-
A.R. Brash Lipoxygenases: occurrence, functions, catalysis, and acquisition of substrate J Biol Chem 274 1999 23679 23682
-
(1999)
J Biol Chem
, vol.274
, pp. 23679-23682
-
-
Brash, A.R.1
-
8
-
-
0035976575
-
Prostaglandins and leukotrienes: Advances in eicosanoid biology
-
C.D. Funk Prostaglandins and leukotrienes: advances in eicosanoid biology Science 294 2001 1871 1875
-
(2001)
Science
, vol.294
, pp. 1871-1875
-
-
Funk, C.D.1
-
9
-
-
0027166718
-
Structure-function properties of human platelet 12-lipoxygenase: Chimeric enzyme and in vitro mutagenesis studies
-
X.S. Chen, and C.D. Funk Structure-function properties of human platelet 12-lipoxygenase: chimeric enzyme and in vitro mutagenesis studies Faseb J 7 1993 694 701
-
(1993)
Faseb J
, vol.7
, pp. 694-701
-
-
Chen, X.S.1
Funk, C.D.2
-
10
-
-
0036669583
-
Mammalian arachidonate 15-lipoxygenases structure, function, and biological implications
-
H. Kuhn, M. Walther, and R.J. Kuban Mammalian arachidonate 15-lipoxygenases structure, function, and biological implications Prostaglandins Other Lipid Mediat 68-69 2002 263 290
-
(2002)
Prostaglandins Other Lipid Mediat
, vol.6869
, pp. 263-290
-
-
Kuhn, H.1
Walther, M.2
Kuban, R.J.3
-
11
-
-
0028216578
-
CDNA cloning, expression, mutagenesis of C-terminal isoleucine, genomic structure, and chromosomal localizations of murine 12-lipoxygenases
-
X.S. Chen, U. Kurre, N.A. Jenkins, N.G. Copeland, and C.D. Funk CDNA cloning, expression, mutagenesis of C-terminal isoleucine, genomic structure, and chromosomal localizations of murine 12-lipoxygenases J Biol Chem 269 1994 13979 13987
-
(1994)
J Biol Chem
, vol.269
, pp. 13979-13987
-
-
Chen, X.S.1
Kurre, U.2
Jenkins, N.A.3
Copeland, N.G.4
Funk, C.D.5
-
12
-
-
0032557633
-
Simultaneous expression of leukocyte-type 12-lipoxygenase and reticulocyte-type 15-lipoxygenase in rabbits
-
M. Berger, K. Schwarz, H. Thiele, I. Reimann, A. Huth, and S. Borngraber Simultaneous expression of leukocyte-type 12-lipoxygenase and reticulocyte-type 15-lipoxygenase in rabbits J Mol Biol 278 1998 935 948
-
(1998)
J Mol Biol
, vol.278
, pp. 935-948
-
-
Berger, M.1
Schwarz, K.2
Thiele, H.3
Reimann, I.4
Huth, A.5
Borngraber, S.6
-
13
-
-
37349120736
-
Arachidonic acid metabolites in the cardiovascular system: The role of lipoxygenase isoforms in atherogenesis with particular emphasis on vascular remodeling
-
H. Kuhn, P. Chaitidis, J. Roffeis, and M. Walther Arachidonic acid metabolites in the cardiovascular system: the role of lipoxygenase isoforms in atherogenesis with particular emphasis on vascular remodeling J Cardiovasc Pharmacol 50 2007 609 620
-
(2007)
J Cardiovasc Pharmacol
, vol.50
, pp. 609-620
-
-
Kuhn, H.1
Chaitidis, P.2
Roffeis, J.3
Walther, M.4
-
14
-
-
0035417925
-
Lipoxygenase modulation to reverse carcinogenesis
-
I. Shureiqi, and S.M. Lippman Lipoxygenase modulation to reverse carcinogenesis Cancer Res 61 2001 6307 6312
-
(2001)
Cancer Res
, vol.61
, pp. 6307-6312
-
-
Shureiqi, I.1
Lippman, S.M.2
-
15
-
-
0029970957
-
Lipoxygenase metabolites induced expression of adhesion molecules and transendothelial migration of monocyte-like HL-60 cells is linked to protein kinase C activation
-
C. Sultana, Y. Shen, V. Rattan, and V.K. Kalra Lipoxygenase metabolites induced expression of adhesion molecules and transendothelial migration of monocyte-like HL-60 cells is linked to protein kinase C activation J Cell Physiol 167 1996 477 487
-
(1996)
J Cell Physiol
, vol.167
, pp. 477-487
-
-
Sultana, C.1
Shen, Y.2
Rattan, V.3
Kalra, V.K.4
-
16
-
-
0035572857
-
Signaling mechanisms of nuclear factor-kappab-mediated activation of inflammatory genes by 13-hydroperoxyoctadecadienoic acid in cultured vascular smooth muscle cells
-
R. Natarajan, M.A. Reddy, K.U. Malik, S. Fatima, and B.V. Khan Signaling mechanisms of nuclear factor-kappab-mediated activation of inflammatory genes by 13-hydroperoxyoctadecadienoic acid in cultured vascular smooth muscle cells Arterioscler Thromb Vasc Biol 21 2001 1408 1413
-
(2001)
Arterioscler Thromb Vasc Biol
, vol.21
, pp. 1408-1413
-
-
Natarajan, R.1
Reddy, M.A.2
Malik, K.U.3
Fatima, S.4
Khan, B.V.5
-
17
-
-
0037155879
-
The oxidized lipid and lipoxygenase product 12(S)-hydroxyeicosatetraenoic acid induces hypertrophy and fibronectin transcription in vascular smooth muscle cells via p38 MAPK and cAMP response element-binding protein activation. Mediation of angiotensin II effects
-
M.A. Reddy, P.R. Thimmalapura, L. Lanting, J.L. Nadler, S. Fatima, and R. Natarajan The oxidized lipid and lipoxygenase product 12(S)- hydroxyeicosatetraenoic acid induces hypertrophy and fibronectin transcription in vascular smooth muscle cells via p38 MAPK and cAMP response element-binding protein activation. Mediation of angiotensin II effects J Biol Chem 277 2002 9920 9928
-
(2002)
J Biol Chem
, vol.277
, pp. 9920-9928
-
-
Reddy, M.A.1
Thimmalapura, P.R.2
Lanting, L.3
Nadler, J.L.4
Fatima, S.5
Natarajan, R.6
-
18
-
-
70350127334
-
Lipoxins: Resolutionary road
-
P. Maderna, and C. Godson Lipoxins: resolutionary road Br J Pharmacol 158 2009 947 959
-
(2009)
Br J Pharmacol
, vol.158
, pp. 947-959
-
-
Maderna, P.1
Godson, C.2
-
19
-
-
77952105540
-
Resolvins and protectins: Natural pharmacophores for resolution biology
-
B.D. Levy Resolvins and protectins: natural pharmacophores for resolution biology Prostaglandins Leukot Essent Fatty Acids 82 2010 327 332
-
(2010)
Prostaglandins Leukot Essent Fatty Acids
, vol.82
, pp. 327-332
-
-
Levy, B.D.1
-
21
-
-
33846001661
-
Protectin D1 is generated in asthma and dampens airway inflammation and hyperresponsiveness
-
B.D. Levy, P. Kohli, K. Gotlinger, O. Haworth, S. Hong, and S. Kazani Protectin D1 is generated in asthma and dampens airway inflammation and hyperresponsiveness J Immunol 178 2007 496 502
-
(2007)
J Immunol
, vol.178
, pp. 496-502
-
-
Levy, B.D.1
Kohli, P.2
Gotlinger, K.3
Haworth, O.4
Hong, S.5
Kazani, S.6
-
22
-
-
33745621719
-
Resolvin D series and protectin D1 mitigate acute kidney injury
-
J.S. Duffield, S. Hong, V.S. Vaidya, Y. Lu, G. Fredman, and C.N. Serhan Resolvin D series and protectin D1 mitigate acute kidney injury J Immunol 177 2006 5902 5911
-
(2006)
J Immunol
, vol.177
, pp. 5902-5911
-
-
Duffield, J.S.1
Hong, S.2
Vaidya, V.S.3
Lu, Y.4
Fredman, G.5
Serhan, C.N.6
-
23
-
-
0031975571
-
Membrane translocation of 15-lipoxygenase in hematopoietic cells is calcium-dependent and activates the oxygenase activity of the enzyme
-
R. Brinckmann, K. Schnurr, D. Heydeck, T. Rosenbach, G. Kolde, and H. Kuhn Membrane translocation of 15-lipoxygenase in hematopoietic cells is calcium-dependent and activates the oxygenase activity of the enzyme Blood 91 1998 64 74
-
(1998)
Blood
, vol.91
, pp. 64-74
-
-
Brinckmann, R.1
Schnurr, K.2
Heydeck, D.3
Rosenbach, T.4
Kolde, G.5
Kuhn, H.6
-
24
-
-
33744550207
-
Inflammation and immune regulation by 12/15-lipoxygenases
-
H. Kuhn, and V.B. O'Donnell Inflammation and immune regulation by 12/15-lipoxygenases Prog Lipid Res 45 2006 334 356
-
(2006)
Prog Lipid Res
, vol.45
, pp. 334-356
-
-
Kuhn, H.1
O'Donnell, V.B.2
-
25
-
-
34547120243
-
Activated platelets and monocytes generate four hydroxyphosphatidylethanolamines via lipoxygenase
-
B.H. Maskrey, A. Bermudez-Fajardo, A.H. Morgan, E. Stewart-Jones, V. Dioszeghy, and G.W. Taylor Activated platelets and monocytes generate four hydroxyphosphatidylethanolamines via lipoxygenase J Biol Chem 282 2007 20151 20163
-
(2007)
J Biol Chem
, vol.282
, pp. 20151-20163
-
-
Maskrey, B.H.1
Bermudez-Fajardo, A.2
Morgan, A.H.3
Stewart-Jones, E.4
Dioszeghy, V.5
Taylor, G.W.6
-
26
-
-
77951214211
-
Phospholipid-esterified eicosanoids are generated in agonist-activated human platelets and enhance tissue factor-dependent thrombin generation
-
C.P. Thomas, L.T. Morgan, B.H. Maskrey, R.C. Murphy, H. Kuhn, and S.L. Hazen Phospholipid-esterified eicosanoids are generated in agonist-activated human platelets and enhance tissue factor-dependent thrombin generation J Biol Chem 285 2010 6891 6903
-
(2010)
J Biol Chem
, vol.285
, pp. 6891-6903
-
-
Thomas, C.P.1
Morgan, L.T.2
Maskrey, B.H.3
Murphy, R.C.4
Kuhn, H.5
Hazen, S.L.6
-
27
-
-
69249139081
-
Phosphatidylethanolamine-esterified eicosanoids in the mouse: Tissue localization and inflammation-dependent formation in Th-2 disease
-
A.H. Morgan, V. Dioszeghy, B.H. Maskrey, C.P. Thomas, S.R. Clark, and S.A. Mathie Phosphatidylethanolamine-esterified eicosanoids in the mouse: tissue localization and inflammation-dependent formation in Th-2 disease J Biol Chem 284 2009 21185 21191
-
(2009)
J Biol Chem
, vol.284
, pp. 21185-21191
-
-
Morgan, A.H.1
Dioszeghy, V.2
Maskrey, B.H.3
Thomas, C.P.4
Clark, S.R.5
Mathie, S.A.6
-
28
-
-
33144489526
-
Novel human lipoxygenase inhibitors discovered using virtual screening with homology models
-
V. Kenyon, I. Chorny, W.J. Carvajal, T.R. Holman, and M.P. Jacobson Novel human lipoxygenase inhibitors discovered using virtual screening with homology models J Med Chem 49 2006 1356 1363
-
(2006)
J Med Chem
, vol.49
, pp. 1356-1363
-
-
Kenyon, V.1
Chorny, I.2
Carvajal, W.J.3
Holman, T.R.4
Jacobson, M.P.5
-
29
-
-
59849119874
-
Eicosanoids: Generation and detection in mammalian cells
-
V.B. O'Donnell, B. Maskrey, and G.W. Taylor Eicosanoids: generation and detection in mammalian cells Methods Mol Biol 462 2009 5 23
-
(2009)
Methods Mol Biol
, vol.462
, pp. 5-23
-
-
O'Donnell, V.B.1
Maskrey, B.2
Taylor, G.W.3
-
30
-
-
76149125754
-
12-Lipoxygenase products reduce insulin secretion and {beta}-cell viability in human islets
-
K. Ma, C.S. Nunemaker, R. Wu, S.K. Chakrabarti, D.A. Taylor-Fishwick, and J.L. Nadler 12-Lipoxygenase products reduce insulin secretion and {beta}-cell viability in human islets J Clin Endocrinol Metab 95 2010 887 893
-
(2010)
J Clin Endocrinol Metab
, vol.95
, pp. 887-893
-
-
Ma, K.1
Nunemaker, C.S.2
Wu, R.3
Chakrabarti, S.K.4
Taylor-Fishwick, D.A.5
Nadler, J.L.6
-
31
-
-
16844383761
-
Activation of 12-lipoxygenase in proinflammatory cytokine-mediated beta cell toxicity
-
M. Chen, Z.D. Yang, K.M. Smith, J.D. Carter, and J.L. Nadler Activation of 12-lipoxygenase in proinflammatory cytokine-mediated beta cell toxicity Diabetologia 48 2005 486 495
-
(2005)
Diabetologia
, vol.48
, pp. 486-495
-
-
Chen, M.1
Yang, Z.D.2
Smith, K.M.3
Carter, J.D.4
Nadler, J.L.5
-
32
-
-
0037192853
-
Genetic regulation of metabolic pathways in beta-cells disrupted by hyperglycemia
-
D.R. Laybutt, A. Sharma, D.C. Sgroi, J. Gaudet, S. Bonner-Weir, and G.C. Weir Genetic regulation of metabolic pathways in beta-cells disrupted by hyperglycemia J Biol Chem 277 2002 10912 10921
-
(2002)
J Biol Chem
, vol.277
, pp. 10912-10921
-
-
Laybutt, D.R.1
Sharma, A.2
Sgroi, D.C.3
Gaudet, J.4
Bonner-Weir, S.5
Weir, G.C.6
-
33
-
-
0027233841
-
Elevated glucose and angiotensin II increase 12-lipoxygenase activity and expression in porcine aortic smooth muscle cells
-
R. Natarajan, J.L. Gu, J. Rossi, N. Gonzales, L. Lanting, and L. Xu Elevated glucose and angiotensin II increase 12-lipoxygenase activity and expression in porcine aortic smooth muscle cells Proc Natl Acad Sci USA 90 1993 4947 4951
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 4947-4951
-
-
Natarajan, R.1
Gu, J.L.2
Rossi, J.3
Gonzales, N.4
Lanting, L.5
Xu, L.6
-
34
-
-
0028874383
-
Evolution of beta-cell dysfunction in the male Zucker diabetic fatty rat
-
Y. Tokuyama, J. Sturis, A.M. DePaoli, J. Takeda, M. Stoffel, and J. Tang Evolution of beta-cell dysfunction in the male Zucker diabetic fatty rat Diabetes 44 1995 1447 1457
-
(1995)
Diabetes
, vol.44
, pp. 1447-1457
-
-
Tokuyama, Y.1
Sturis, J.2
Depaoli, A.M.3
Takeda, J.4
Stoffel, M.5
Tang, J.6
-
35
-
-
57049099790
-
12-Lipoxygenase-knockout mice are resistant to inflammatory effects of obesity induced by Western diet
-
C.S. Nunemaker, M. Chen, H. Pei, S.D. Kimble, S.R. Keller, and J.D. Carter 12-Lipoxygenase-knockout mice are resistant to inflammatory effects of obesity induced by Western diet Am J Physiol Endocrinol Metab 295 2008 E1065 E1075
-
(2008)
Am J Physiol Endocrinol Metab
, vol.295
-
-
Nunemaker, C.S.1
Chen, M.2
Pei, H.3
Kimble, S.D.4
Keller, S.R.5
Carter, J.D.6
-
36
-
-
70349639659
-
12/15-lipoxygenase is required for the early onset of high fat diet-induced adipose tissue inflammation and insulin resistance in mice
-
D.D. Sears, P.D. Miles, J. Chapman, J.M. Ofrecio, F. Almazan, and D. Thapar 12/15-lipoxygenase is required for the early onset of high fat diet-induced adipose tissue inflammation and insulin resistance in mice PLoS One 4 2009 e7250
-
(2009)
PLoS One
, vol.4
, pp. 7250
-
-
Sears, D.D.1
Miles, P.D.2
Chapman, J.3
Ofrecio, J.M.4
Almazan, F.5
Thapar, D.6
-
37
-
-
0032723345
-
Resistance to type 1 diabetes induction in 12-lipoxygenase knockout mice
-
D. Bleich, S. Chen, B. Zipser, D. Sun, C.D. Funk, and J.L. Nadler Resistance to type 1 diabetes induction in 12-lipoxygenase knockout mice J Clin Invest 103 1999 1431 1436
-
(1999)
J Clin Invest
, vol.103
, pp. 1431-1436
-
-
Bleich, D.1
Chen, S.2
Zipser, B.3
Sun, D.4
Funk, C.D.5
Nadler, J.L.6
-
38
-
-
38449098081
-
Nonobese diabetic (NOD) mice congenic for a targeted deletion of 12/15-lipoxygenase are protected from autoimmune diabetes
-
M. McDuffie, N.A. Maybee, S.R. Keller, B.K. Stevens, J.C. Garmey, and M.A. Morris Nonobese diabetic (NOD) mice congenic for a targeted deletion of 12/15-lipoxygenase are protected from autoimmune diabetes Diabetes 57 2008 199 208
-
(2008)
Diabetes
, vol.57
, pp. 199-208
-
-
McDuffie, M.1
Maybee, N.A.2
Keller, S.R.3
Stevens, B.K.4
Garmey, J.C.5
Morris, M.A.6
-
39
-
-
0036141930
-
Lipoxin-mediated inhibition of IL-12 production by DCs: A mechanism for regulation of microbial immunity
-
J. Aliberti, S. Hieny, C. Reis e Sousa, C.N. Serhan, and A. Sher Lipoxin-mediated inhibition of IL-12 production by DCs: a mechanism for regulation of microbial immunity Nat Immunol 3 2002 76 82
-
(2002)
Nat Immunol
, vol.3
, pp. 76-82
-
-
Aliberti, J.1
Hieny, S.2
Reis Sousa e, C.3
Serhan, C.N.4
Sher, A.5
-
40
-
-
0037144594
-
Selective interleukin-12 synthesis defect in 12/15-lipoxygenase-deficient macrophages associated with reduced atherosclerosis in a mouse model of familial hypercholesterolemia
-
L. Zhao, C.A. Cuff, E. Moss, U. Wille, T. Cyrus, and E.A. Klein Selective interleukin-12 synthesis defect in 12/15-lipoxygenase-deficient macrophages associated with reduced atherosclerosis in a mouse model of familial hypercholesterolemia J Biol Chem 277 2002 35350 35356
-
(2002)
J Biol Chem
, vol.277
, pp. 35350-35356
-
-
Zhao, L.1
Cuff, C.A.2
Moss, E.3
Wille, U.4
Cyrus, T.5
Klein, E.A.6
-
41
-
-
29644436198
-
Cellular and molecular mechanisms of the selective regulation of IL-12 production by 12/15-lipoxygenase
-
M.K. Middleton, T. Rubinstein, and E. Pure Cellular and molecular mechanisms of the selective regulation of IL-12 production by 12/15-lipoxygenase J Immunol 176 2006 265 274
-
(2006)
J Immunol
, vol.176
, pp. 265-274
-
-
Middleton, M.K.1
Rubinstein, T.2
Pure, E.3
-
42
-
-
72449156038
-
12/15-lipoxygenase-dependent myeloid production of interleukin-12 is essential for resistance to chronic toxoplasmosis
-
M.K. Middleton, A.M. Zukas, T. Rubinstein, M. Kinder, E.H. Wilson, and P. Zhu 12/15-lipoxygenase-dependent myeloid production of interleukin-12 is essential for resistance to chronic toxoplasmosis Infect Immun 77 2009 5690 5700
-
(2009)
Infect Immun
, vol.77
, pp. 5690-5700
-
-
Middleton, M.K.1
Zukas, A.M.2
Rubinstein, T.3
Kinder, M.4
Wilson, E.H.5
Zhu, P.6
-
43
-
-
0028972876
-
Interleukin-1 beta regulates the expression of a leukocyte type of 12-lipoxygenase in rat islets and RIN m5F cells
-
D. Bleich, S. Chen, J.L. Gu, L. Thomas, S. Scott, and N. Gonzales Interleukin-1 beta regulates the expression of a leukocyte type of 12-lipoxygenase in rat islets and RIN m5F cells Endocrinology 136 1995 5736 5744
-
(1995)
Endocrinology
, vol.136
, pp. 5736-5744
-
-
Bleich, D.1
Chen, S.2
Gu, J.L.3
Thomas, L.4
Scott, S.5
Gonzales, N.6
-
44
-
-
0031566151
-
The stress-activated c-Jun protein kinase (JNK) is stimulated by lipoxygenase pathway product 12-HETE in RIN m5F cells
-
D. Bleich, S. Chen, Y. Wen, and J.L. Nadler The stress-activated c-Jun protein kinase (JNK) is stimulated by lipoxygenase pathway product 12-HETE in RIN m5F cells Biochem Biophys Res Commun 230 1997 448 451
-
(1997)
Biochem Biophys Res Commun
, vol.230
, pp. 448-451
-
-
Bleich, D.1
Chen, S.2
Wen, Y.3
Nadler, J.L.4
-
45
-
-
0041664876
-
Evidence that increased 12-lipoxygenase expression impairs pancreatic beta cell function and viability
-
K.M. Prasad, P.R. Thimmalapura, E.A. Woode, and J.L. Nadler Evidence that increased 12-lipoxygenase expression impairs pancreatic beta cell function and viability Biochem Biophys Res Commun 308 2003 427 432
-
(2003)
Biochem Biophys Res Commun
, vol.308
, pp. 427-432
-
-
Prasad, K.M.1
Thimmalapura, P.R.2
Woode, E.A.3
Nadler, J.L.4
-
46
-
-
36048930552
-
12(S)-hydroperoxyeicosatetraenoic acid (12-HETE) increases mitochondrial nitric oxide by increasing intramitochondrial calcium
-
R.R. Nazarewicz, W.J. Zenebe, A. Parihar, M.S. Parihar, M. Vaccaro, and C. Rink 12(S)-hydroperoxyeicosatetraenoic acid (12-HETE) increases mitochondrial nitric oxide by increasing intramitochondrial calcium Arch Biochem Biophys 468 2007 114 120
-
(2007)
Arch Biochem Biophys
, vol.468
, pp. 114-120
-
-
Nazarewicz, R.R.1
Zenebe, W.J.2
Parihar, A.3
Parihar, M.S.4
Vaccaro, M.5
Rink, C.6
-
47
-
-
0038448178
-
5-Lipoxygenase-derived leukotrienes: Mediators also of atherosclerotic inflammation
-
O. Radmark 5-Lipoxygenase-derived leukotrienes: mediators also of atherosclerotic inflammation Arterioscler Thromb Vasc Biol 23 2003 1140 1142
-
(2003)
Arterioscler Thromb Vasc Biol
, vol.23
, pp. 1140-1142
-
-
Radmark, O.1
-
48
-
-
33847034426
-
The role of arachidonic acid and its metabolites in insulin secretion from human islets of langerhans
-
S.J. Persaud, D. Muller, V.D. Belin, I. Kitsou-Mylona, H. Asare-Anane, and A. Papadimitriou The role of arachidonic acid and its metabolites in insulin secretion from human islets of langerhans Diabetes 56 2007 197 203
-
(2007)
Diabetes
, vol.56
, pp. 197-203
-
-
Persaud, S.J.1
Muller, D.2
Belin, V.D.3
Kitsou-Mylona, I.4
Asare-Anane, H.5
Papadimitriou, A.6
-
49
-
-
0036716833
-
Induction of cyclooxygenase-2 gene in pancreatic beta-cells by 12-lipoxygenase pathway product 12-hydroxyeicosatetraenoic acid
-
X. Han, S. Chen, Y. Sun, J.L. Nadler, and D. Bleich Induction of cyclooxygenase-2 gene in pancreatic beta-cells by 12-lipoxygenase pathway product 12-hydroxyeicosatetraenoic acid Mol Endocrinol 16 2002 2145 2154
-
(2002)
Mol Endocrinol
, vol.16
, pp. 2145-2154
-
-
Han, X.1
Chen, S.2
Sun, Y.3
Nadler, J.L.4
Bleich, D.5
-
50
-
-
0037449723
-
Minimally modified LDL binds to CD14, induces macrophage spreading via TLR4/MD-2, and inhibits phagocytosis of apoptotic cells
-
Y.I. Miller, S. Viriyakosol, C.J. Binder, J.R. Feramisco, T.N. Kirkland, and J.L. Witztum Minimally modified LDL binds to CD14, induces macrophage spreading via TLR4/MD-2, and inhibits phagocytosis of apoptotic cells J Biol Chem 278 2003 1561 1568
-
(2003)
J Biol Chem
, vol.278
, pp. 1561-1568
-
-
Miller, Y.I.1
Viriyakosol, S.2
Binder, C.J.3
Feramisco, J.R.4
Kirkland, T.N.5
Witztum, J.L.6
-
51
-
-
20144385204
-
Toll-like receptor 4-dependent and -independent cytokine secretion induced by minimally oxidized low-density lipoprotein in macrophages
-
Y.I. Miller, S. Viriyakosol, D.S. Worrall, A. Boullier, S. Butler, and J.L. Witztum Toll-like receptor 4-dependent and -independent cytokine secretion induced by minimally oxidized low-density lipoprotein in macrophages Arterioscler Thromb Vasc Biol 25 2005 1213 1219
-
(2005)
Arterioscler Thromb Vasc Biol
, vol.25
, pp. 1213-1219
-
-
Miller, Y.I.1
Viriyakosol, S.2
Worrall, D.S.3
Boullier, A.4
Butler, S.5
Witztum, J.L.6
-
52
-
-
0020570204
-
Lipoxygenase pathway in islet endocrine cells. Oxidative metabolism of arachidonic acid promotes insulin release
-
S. Metz, M. VanRollins, R. Strife, W. Fujimoto, and R.P. Robertson Lipoxygenase pathway in islet endocrine cells. Oxidative metabolism of arachidonic acid promotes insulin release J Clin Invest 71 1983 1191 1205
-
(1983)
J Clin Invest
, vol.71
, pp. 1191-1205
-
-
Metz, S.1
Vanrollins, M.2
Strife, R.3
Fujimoto, W.4
Robertson, R.P.5
-
53
-
-
0021921015
-
Glucose increases the synthesis of lipoxygenase-mediated metabolites of arachidonic acid in intact rat islets
-
S.A. Metz Glucose increases the synthesis of lipoxygenase-mediated metabolites of arachidonic acid in intact rat islets Proc Natl Acad Sci USA 82 1985 198 202
-
(1985)
Proc Natl Acad Sci USA
, vol.82
, pp. 198-202
-
-
Metz, S.A.1
-
54
-
-
0021907945
-
Arachidonic acid metabolism in isolated pancreatic islets. III. Effects of exogenous lipoxygenase products and inhibitors on insulin secretion
-
J. Turk, J.R. Colca, and M.L. McDaniel Arachidonic acid metabolism in isolated pancreatic islets. III. Effects of exogenous lipoxygenase products and inhibitors on insulin secretion Biochim Biophys Acta 834 1985 23 36
-
(1985)
Biochim Biophys Acta
, vol.834
, pp. 23-36
-
-
Turk, J.1
Colca, J.R.2
McDaniel, M.L.3
-
55
-
-
0026454365
-
Selective expression of an arachidonate 12-lipoxygenase by pancreatic islet beta-cells
-
V.R. Shannon, S. Ramanadham, J. Turk, and M.J. Holtzman Selective expression of an arachidonate 12-lipoxygenase by pancreatic islet beta-cells Am J Physiol 263 1992 E828 E836
-
(1992)
Am J Physiol
, vol.263
-
-
Shannon, V.R.1
Ramanadham, S.2
Turk, J.3
Holtzman, M.J.4
-
56
-
-
0033808074
-
Expression of arachidonate 12-lipoxygenase in rat tissues: A possible role in glucagon secretion
-
H. Kawajiri, D. Zhuang, N. Qiao, T. Yoshimoto, M. Yamamoto, and S. Iseki Expression of arachidonate 12-lipoxygenase in rat tissues: a possible role in glucagon secretion J Histochem Cytochem 48 2000 1411 1419
-
(2000)
J Histochem Cytochem
, vol.48
, pp. 1411-1419
-
-
Kawajiri, H.1
Zhuang, D.2
Qiao, N.3
Yoshimoto, T.4
Yamamoto, M.5
Iseki, S.6
-
57
-
-
34547399482
-
High-fat diet induced neuropathy of pre-diabetes and obesity: Effects of "healthy" diet and aldose reductase inhibition
-
I.G. Obrosova, O. Ilnytska, V.V. Lyzogubov, I.A. Pavlov, N. Mashtalir, and J.L. Nadler High-fat diet induced neuropathy of pre-diabetes and obesity: effects of "healthy" diet and aldose reductase inhibition Diabetes 56 2007 2598 2608
-
(2007)
Diabetes
, vol.56
, pp. 2598-2608
-
-
Obrosova, I.G.1
Ilnytska, O.2
Lyzogubov, V.V.3
Pavlov, I.A.4
Mashtalir, N.5
Nadler, J.L.6
-
58
-
-
77952501888
-
High-fat diet-induced neuropathy of prediabetes and obesity: Effect of PMI-5011, an ethanolic extract of Artemisia dracunculus L
-
P. Watcho, R. Stavniichuk, D.M. Ribnicky, I. Raskin, and I.G. Obrosova High-fat diet-induced neuropathy of prediabetes and obesity: effect of PMI-5011, an ethanolic extract of Artemisia dracunculus L. Mediators Inflamm 2010 2010 268547
-
(2010)
Mediators Inflamm
, vol.2010
, pp. 268547
-
-
Watcho, P.1
Stavniichuk, R.2
Ribnicky, D.M.3
Raskin, I.4
Obrosova, I.G.5
-
59
-
-
77955509447
-
Role of 12/15-lipoxygenase in nitrosative stress and peripheral prediabetic and diabetic neuropathies
-
Stavniichuk R, Drel VR, Shevalye H, Vareniuk I, Stevens MJ, Nadler JL, et al. Role of 12/15-lipoxygenase in nitrosative stress and peripheral prediabetic and diabetic neuropathies. Free Radic Biol Med 2010.
-
(2010)
Free Radic Biol Med
-
-
Stavniichuk, R.1
Drel, V.R.2
Shevalye, H.3
Vareniuk, I.4
Stevens, M.J.5
Nadler, J.L.6
-
60
-
-
0031014333
-
Detection of eicosanoids in epiretinal membranes of patients suffering from proliferative vitreoretinal diseases
-
A.J. Augustin, F.H. Grus, F. Koch, and M. Spitznas Detection of eicosanoids in epiretinal membranes of patients suffering from proliferative vitreoretinal diseases Br J Ophthalmol 81 1997 58 60
-
(1997)
Br J Ophthalmol
, vol.81
, pp. 58-60
-
-
Augustin, A.J.1
Grus, F.H.2
Koch, F.3
Spitznas, M.4
-
61
-
-
77954264059
-
Profile of lipid and protein autacoids in diabetic vitreous correlates with the progression of diabetic retinopathy
-
M.L. Schwartzman, P. Iserovich, K. Gotlinger, L. Bellner, M.W. Dunn, and M. Sartore Profile of lipid and protein autacoids in diabetic vitreous correlates with the progression of diabetic retinopathy Diabetes 59 2010 1780 1788
-
(2010)
Diabetes
, vol.59
, pp. 1780-1788
-
-
Schwartzman, M.L.1
Iserovich, P.2
Gotlinger, K.3
Bellner, L.4
Dunn, M.W.5
Sartore, M.6
-
62
-
-
48449097142
-
5-Lipoxygenase, but not 12/15-lipoxygenase, contributes to degeneration of retinal capillaries in a mouse model of diabetic retinopathy
-
R.A. Gubitosi-Klug, R. Talahalli, Y. Du, J.L. Nadler, and T.S. Kern 5-Lipoxygenase, but not 12/15-lipoxygenase, contributes to degeneration of retinal capillaries in a mouse model of diabetic retinopathy Diabetes 57 2008 1387 1393
-
(2008)
Diabetes
, vol.57
, pp. 1387-1393
-
-
Gubitosi-Klug, R.A.1
Talahalli, R.2
Du, Y.3
Nadler, J.L.4
Kern, T.S.5
-
63
-
-
0242468739
-
Adipocyte differentiation of 3T3-L1 preadipocytes is dependent on lipoxygenase activity during the initial stages of the differentiation process
-
L. Madsen, R.K. Petersen, M.B. Sorensen, C. Jorgensen, P. Hallenborg, and L. Pridal Adipocyte differentiation of 3T3-L1 preadipocytes is dependent on lipoxygenase activity during the initial stages of the differentiation process Biochem J 375 2003 539 549
-
(2003)
Biochem J
, vol.375
, pp. 539-549
-
-
Madsen, L.1
Petersen, R.K.2
Sorensen, M.B.3
Jorgensen, C.4
Hallenborg, P.5
Pridal, L.6
-
64
-
-
0016178461
-
An established pre-adipose cell line and its differentiation in culture
-
H. Green, and M. Meuth An established pre-adipose cell line and its differentiation in culture Cell 3 1974 127 133
-
(1974)
Cell
, vol.3
, pp. 127-133
-
-
Green, H.1
Meuth, M.2
-
65
-
-
0019203221
-
Search for the adipocyte precursor cell and factors that promote its differentiation
-
G.J. Hausman, D.R. Campion, and R.J. Martin Search for the adipocyte precursor cell and factors that promote its differentiation J Lipid Res 21 1980 657 670
-
(1980)
J Lipid Res
, vol.21
, pp. 657-670
-
-
Hausman, G.J.1
Campion, D.R.2
Martin, R.J.3
-
66
-
-
0033213637
-
PPAR gamma is required for placental, cardiac, and adipose tissue development
-
Y. Barak, M.C. Nelson, E.S. Ong, Y.Z. Jones, P. Ruiz-Lozano, and K.R. Chien PPAR gamma is required for placental, cardiac, and adipose tissue development Mol Cell 4 1999 585 595
-
(1999)
Mol Cell
, vol.4
, pp. 585-595
-
-
Barak, Y.1
Nelson, M.C.2
Ong, E.S.3
Jones, Y.Z.4
Ruiz-Lozano, P.5
Chien, K.R.6
-
67
-
-
0033212964
-
PPAR gamma mediates high-fat diet-induced adipocyte hypertrophy and insulin resistance
-
N. Kubota, Y. Terauchi, H. Miki, H. Tamemoto, T. Yamauchi, and K. Komeda PPAR gamma mediates high-fat diet-induced adipocyte hypertrophy and insulin resistance Mol Cell 4 1999 597 609
-
(1999)
Mol Cell
, vol.4
, pp. 597-609
-
-
Kubota, N.1
Terauchi, Y.2
Miki, H.3
Tamemoto, H.4
Yamauchi, T.5
Komeda, K.6
-
68
-
-
0033213631
-
PPAR gamma is required for the differentiation of adipose tissue in vivo and in vitro
-
E.D. Rosen, P. Sarraf, A.E. Troy, G. Bradwin, K. Moore, and D.S. Milstone PPAR gamma is required for the differentiation of adipose tissue in vivo and in vitro Mol Cell 4 1999 611 617
-
(1999)
Mol Cell
, vol.4
, pp. 611-617
-
-
Rosen, E.D.1
Sarraf, P.2
Troy, A.E.3
Bradwin, G.4
Moore, K.5
Milstone, D.S.6
-
69
-
-
0028802627
-
Differential activation of peroxisome proliferator-activated receptors by eicosanoids
-
K. Yu, W. Bayona, C.B. Kallen, H.P. Harding, C.P. Ravera, and G. McMahon Differential activation of peroxisome proliferator-activated receptors by eicosanoids J Biol Chem 270 1995 23975 23983
-
(1995)
J Biol Chem
, vol.270
, pp. 23975-23983
-
-
Yu, K.1
Bayona, W.2
Kallen, C.B.3
Harding, H.P.4
Ravera, C.P.5
McMahon, G.6
-
70
-
-
0032540325
-
Oxidized LDL regulates macrophage gene expression through ligand activation of PPARgamma
-
L. Nagy, P. Tontonoz, J.G. Alvarez, H. Chen, and R.M. Evans Oxidized LDL regulates macrophage gene expression through ligand activation of PPARgamma Cell 93 1998 229 240
-
(1998)
Cell
, vol.93
, pp. 229-240
-
-
Nagy, L.1
Tontonoz, P.2
Alvarez, J.G.3
Chen, H.4
Evans, R.M.5
-
71
-
-
0033595261
-
Interleukin-4-dependent production of PPAR-gamma ligands in macrophages by 12/15-lipoxygenase
-
J.T. Huang, J.S. Welch, M. Ricote, C.J. Binder, T.M. Willson, and C. Kelly Interleukin-4-dependent production of PPAR-gamma ligands in macrophages by 12/15-lipoxygenase Nature 400 1999 378 382
-
(1999)
Nature
, vol.400
, pp. 378-382
-
-
Huang, J.T.1
Welch, J.S.2
Ricote, M.3
Binder, C.J.4
Willson, T.M.5
Kelly, C.6
-
72
-
-
0035863307
-
15S-Hydroxyeicosatetraenoic acid activates peroxisome proliferator-activated receptor gamma and inhibits proliferation in PC3 prostate carcinoma cells
-
S.B. Shappell, R.A. Gupta, S. Manning, R. Whitehead, W.E. Boeglin, and C. Schneider 15S-Hydroxyeicosatetraenoic acid activates peroxisome proliferator-activated receptor gamma and inhibits proliferation in PC3 prostate carcinoma cells Cancer Res 61 2001 497 503
-
(2001)
Cancer Res
, vol.61
, pp. 497-503
-
-
Shappell, S.B.1
Gupta, R.A.2
Manning, S.3
Whitehead, R.4
Boeglin, W.E.5
Schneider, C.6
-
73
-
-
0037189536
-
15-Lipoxygenase metabolism of 2-arachidonylglycerol. Generation of a peroxisome proliferator-activated receptor alpha agonist
-
K.R. Kozak, R.A. Gupta, J.S. Moody, C. Ji, W.E. Boeglin, and R.N. DuBois 15-Lipoxygenase metabolism of 2-arachidonylglycerol. Generation of a peroxisome proliferator-activated receptor alpha agonist J Biol Chem 277 2002 23278 23286
-
(2002)
J Biol Chem
, vol.277
, pp. 23278-23286
-
-
Kozak, K.R.1
Gupta, R.A.2
Moody, J.S.3
Ji, C.4
Boeglin, W.E.5
Dubois, R.N.6
-
74
-
-
0035937793
-
Arachidonic acid stimulates glucose uptake in 3T3-L1 adipocytes by increasing GLUT1 and GLUT4 levels at the plasma membrane. Evidence for involvement of lipoxygenase metabolites and peroxisome proliferator-activated receptor gamma
-
C. Nugent, J.B. Prins, J.P. Whitehead, J.M. Wentworth, V.K. Chatterjee, and S. O'Rahilly Arachidonic acid stimulates glucose uptake in 3T3-L1 adipocytes by increasing GLUT1 and GLUT4 levels at the plasma membrane. Evidence for involvement of lipoxygenase metabolites and peroxisome proliferator-activated receptor gamma J Biol Chem 276 2001 9149 9157
-
(2001)
J Biol Chem
, vol.276
, pp. 9149-9157
-
-
Nugent, C.1
Prins, J.B.2
Whitehead, J.P.3
Wentworth, J.M.4
Chatterjee, V.K.5
O'Rahilly, S.6
-
75
-
-
0033039239
-
Basal transepidermal water loss is increased in platelet-type 12-lipoxygenase deficient mice
-
E.N. Johnson, L.B. Nanney, J. Virmani, J.A. Lawson, and C.D. Funk Basal transepidermal water loss is increased in platelet-type 12-lipoxygenase deficient mice J Invest Dermatol 112 1999 861 865
-
(1999)
J Invest Dermatol
, vol.112
, pp. 861-865
-
-
Johnson, E.N.1
Nanney, L.B.2
Virmani, J.3
Lawson, J.A.4
Funk, C.D.5
-
76
-
-
69749102190
-
12/15-Lipoxygenase Products Induce Inflammation and Impair Insulin Signaling in 3T3-L1 Adipocytes
-
Chakrabarti SK, Cole BK, Wen Y, Keller SR, Nadler JL. 12/15-Lipoxygenase Products Induce Inflammation and Impair Insulin Signaling in 3T3-L1 Adipocytes. Obesity (Silver Spring), 2009.
-
(2009)
Obesity (Silver Spring)
-
-
Chakrabarti, S.K.1
Cole, B.K.2
Wen, Y.3
Keller, S.R.4
Nadler, J.L.5
-
77
-
-
0029844659
-
Disruption of 12/15-lipoxygenase expression in peritoneal macrophages. Enhanced utilization of the 5-lipoxygenase pathway and diminished oxidation of low density lipoprotein
-
D. Sun, and C.D. Funk Disruption of 12/15-lipoxygenase expression in peritoneal macrophages. Enhanced utilization of the 5-lipoxygenase pathway and diminished oxidation of low density lipoprotein J Biol Chem 271 1996 24055 24062
-
(1996)
J Biol Chem
, vol.271
, pp. 24055-24062
-
-
Sun, D.1
Funk, C.D.2
-
78
-
-
77955649322
-
Epidermis-type lipoxygenase 3 regulates adipocyte differentiation and peroxisome proliferator-activated receptor gamma activity
-
P. Hallenborg, C. Jorgensen, R.K. Petersen, S. Feddersen, P. Araujo, and P. Markt Epidermis-type lipoxygenase 3 regulates adipocyte differentiation and peroxisome proliferator-activated receptor gamma activity Mol Cell Biol 30 2010 4077 4091
-
(2010)
Mol Cell Biol
, vol.30
, pp. 4077-4091
-
-
Hallenborg, P.1
Jorgensen, C.2
Petersen, R.K.3
Feddersen, S.4
Araujo, P.5
Markt, P.6
-
79
-
-
0017119837
-
Induction of lipogenesis during differentiation in a " preadipocyte" cell line
-
J.C. Mackall, A.K. Student, S.E. Polakis, and M.D. Lane Induction of lipogenesis during differentiation in a "preadipocyte" cell line J Biol Chem 251 1976 6462 6464
-
(1976)
J Biol Chem
, vol.251
, pp. 6462-6464
-
-
MacKall, J.C.1
Student, A.K.2
Polakis, S.E.3
Lane, M.D.4
-
80
-
-
67651216391
-
Adipokines as regulators of muscle metabolism and insulin sensitivity
-
D.J. Dyck Adipokines as regulators of muscle metabolism and insulin sensitivity Appl Physiol Nutr Metab 34 2009 396 402
-
(2009)
Appl Physiol Nutr Metab
, vol.34
, pp. 396-402
-
-
Dyck, D.J.1
-
81
-
-
70349234521
-
Increased adipose tissue expression of lipocalin-2 in obesity is related to inflammation and matrix metalloproteinase-2 and metalloproteinase-9 activities in humans
-
V. Catalan, J. Gomez-Ambrosi, A. Rodriguez, B. Ramirez, C. Silva, and F. Rotellar Increased adipose tissue expression of lipocalin-2 in obesity is related to inflammation and matrix metalloproteinase-2 and metalloproteinase-9 activities in humans J Mol Med 87 2009 803 813
-
(2009)
J Mol Med
, vol.87
, pp. 803-813
-
-
Catalan, V.1
Gomez-Ambrosi, J.2
Rodriguez, A.3
Ramirez, B.4
Silva, C.5
Rotellar, F.6
-
82
-
-
33845973764
-
Lipocalin-2 is an inflammatory marker closely associated with obesity, insulin resistance, and hyperglycemia in humans
-
Y. Wang, K.S. Lam, E.W. Kraegen, G. Sweeney, J. Zhang, and A.W. Tso Lipocalin-2 is an inflammatory marker closely associated with obesity, insulin resistance, and hyperglycemia in humans Clin Chem 53 2007 34 41
-
(2007)
Clin Chem
, vol.53
, pp. 34-41
-
-
Wang, Y.1
Lam, K.S.2
Kraegen, E.W.3
Sweeney, G.4
Zhang, J.5
Tso, A.W.6
-
83
-
-
44649173850
-
The role of lipocalin 2 in the regulation of inflammation in adipocytes and macrophages
-
J. Zhang, Y. Wu, Y. Zhang, D. Leroith, D.A. Bernlohr, and X. Chen The role of lipocalin 2 in the regulation of inflammation in adipocytes and macrophages Mol Endocrinol 22 2008 1416 1426
-
(2008)
Mol Endocrinol
, vol.22
, pp. 1416-1426
-
-
Zhang, J.1
Wu, Y.2
Zhang, Y.3
Leroith, D.4
Bernlohr, D.A.5
Chen, X.6
-
84
-
-
77951193688
-
Lipocalin-2 deficiency attenuates insulin resistance associated with aging and obesity
-
I.K. Law, A. Xu, K.S. Lam, T. Berger, T.W. Mak, and P.M. Vanhoutte Lipocalin-2 deficiency attenuates insulin resistance associated with aging and obesity Diabetes 59 2010 872 882
-
(2010)
Diabetes
, vol.59
, pp. 872-882
-
-
Law, I.K.1
Xu, A.2
Lam, K.S.3
Berger, T.4
Mak, T.W.5
Vanhoutte, P.M.6
-
85
-
-
77149139835
-
Valsartan protects pancreatic islets and adipose tissue from the inflammatory and metabolic consequences of a high-fat diet in mice
-
B.K. Cole, S.R. Keller, R. Wu, J.D. Carter, J.L. Nadler, and C.S. Nunemaker Valsartan protects pancreatic islets and adipose tissue from the inflammatory and metabolic consequences of a high-fat diet in mice Hypertension 55 2010 715 721
-
(2010)
Hypertension
, vol.55
, pp. 715-721
-
-
Cole, B.K.1
Keller, S.R.2
Wu, R.3
Carter, J.D.4
Nadler, J.L.5
Nunemaker, C.S.6
-
86
-
-
0032911057
-
The diversity of the lipoxygenase family. Many sequence data but little information on biological significance
-
H. Kuhn, and B.J. Thiele The diversity of the lipoxygenase family. Many sequence data but little information on biological significance FEBS Lett 449 1999 7 11
-
(1999)
FEBS Lett
, vol.449
, pp. 7-11
-
-
Kuhn, H.1
Thiele, B.J.2
-
87
-
-
0036244676
-
The specificity of lipoxygenase-catalyzed lipid peroxidation and the effects of radical-scavenging antioxidants
-
N. Noguchi, H. Yamashita, J. Hamahara, A. Nakamura, H. Kuhn, and E. Niki The specificity of lipoxygenase-catalyzed lipid peroxidation and the effects of radical-scavenging antioxidants Biol Chem 383 2002 619 626
-
(2002)
Biol Chem
, vol.383
, pp. 619-626
-
-
Noguchi, N.1
Yamashita, H.2
Hamahara, J.3
Nakamura, A.4
Kuhn, H.5
Niki, E.6
-
88
-
-
33847638020
-
Eicosanoids in inflammation: Biosynthesis, pharmacology, and therapeutic frontiers
-
S.P. Khanapure, D.S. Garvey, D.R. Janero, and L.G. Letts Eicosanoids in inflammation: biosynthesis, pharmacology, and therapeutic frontiers Curr Top Med Chem 7 2007 311 340
-
(2007)
Curr Top Med Chem
, vol.7
, pp. 311-340
-
-
Khanapure, S.P.1
Garvey, D.S.2
Janero, D.R.3
Letts, L.G.4
-
89
-
-
40349100270
-
Endogenous pro-resolving and anti-inflammatory lipid mediators: A new pharmacologic genus
-
C.N. Serhan, and N. Chiang Endogenous pro-resolving and anti-inflammatory lipid mediators: a new pharmacologic genus Br J Pharmacol 153 Suppl 1 2008 S200 S215
-
(2008)
Br J Pharmacol
, vol.153
, Issue.SUPPL. 1
-
-
Serhan, C.N.1
Chiang, N.2
-
90
-
-
42649089790
-
Resolving inflammation: Dual anti-inflammatory and pro-resolution lipid mediators
-
C.N. Serhan, N. Chiang, and T.E. Van Dyke Resolving inflammation: dual anti-inflammatory and pro-resolution lipid mediators Nat Rev Immunol 8 2008 349 361
-
(2008)
Nat Rev Immunol
, vol.8
, pp. 349-361
-
-
Serhan, C.N.1
Chiang, N.2
Van Dyke, T.E.3
-
91
-
-
41749090254
-
Anti-inflammatory and proresolving lipid mediators
-
C.N. Serhan, S. Yacoubian, and R. Yang Anti-inflammatory and proresolving lipid mediators Ann Rev Pathol 3 2008 279 312
-
(2008)
Ann Rev Pathol
, vol.3
, pp. 279-312
-
-
Serhan, C.N.1
Yacoubian, S.2
Yang, R.3
-
93
-
-
33846980154
-
Adenoviral expression of 15-lipoxygenase-1 in rabbit aortic endothelium: Role in arachidonic acid-induced relaxation
-
N.T. Aggarwal, B.B. Holmes, L. Cui, H. Viita, S. Yla-Herttuala, and W.B. Campbell Adenoviral expression of 15-lipoxygenase-1 in rabbit aortic endothelium: role in arachidonic acid-induced relaxation Am J Physiol Heart Circ Physiol 292 2007 H1033 H1041
-
(2007)
Am J Physiol Heart Circ Physiol
, vol.292
-
-
Aggarwal, N.T.1
Holmes, B.B.2
Cui, L.3
Viita, H.4
Yla-Herttuala, S.5
Campbell, W.B.6
-
95
-
-
33644824103
-
Reticulocyte 15-lipoxygenase-I is important in acetylcholine-induced endothelium-dependent vasorelaxation in rabbit aorta
-
X. Tang, B.B. Holmes, K. Nithipatikom, C.J. Hillard, H. Kuhn, and W.B. Campbell Reticulocyte 15-lipoxygenase-I is important in acetylcholine-induced endothelium-dependent vasorelaxation in rabbit aorta Arterioscler Thromb Vasc Biol 26 2006 78 84
-
(2006)
Arterioscler Thromb Vasc Biol
, vol.26
, pp. 78-84
-
-
Tang, X.1
Holmes, B.B.2
Nithipatikom, K.3
Hillard, C.J.4
Kuhn, H.5
Campbell, W.B.6
-
96
-
-
0023920874
-
Arachidonate 15-lipoxygenase (omega-6 lipoxygenase) from human leukocytes. Purification and structural homology to other mammalian lipoxygenases
-
E. Sigal, D. Grunberger, C.S. Craik, G.H. Caughey, and J.A. Nadel Arachidonate 15-lipoxygenase (omega-6 lipoxygenase) from human leukocytes. Purification and structural homology to other mammalian lipoxygenases J Biol Chem 263 1988 5328 5332
-
(1988)
J Biol Chem
, vol.263
, pp. 5328-5332
-
-
Sigal, E.1
Grunberger, D.2
Craik, C.S.3
Caughey, G.H.4
Nadel, J.A.5
-
97
-
-
0026541324
-
Effects of various cyclooxygenase and lipoxygenase metabolites on guinea-pig cerebral arteries
-
T.K. Uski, and E.D. Hogestatt Effects of various cyclooxygenase and lipoxygenase metabolites on guinea-pig cerebral arteries Gen Pharmacol 23 1992 109 113
-
(1992)
Gen Pharmacol
, vol.23
, pp. 109-113
-
-
Uski, T.K.1
Hogestatt, E.D.2
-
98
-
-
13244290059
-
Nitric oxide, peroxynitrite and lipoxygenase in atherogenesis: Mechanistic insights
-
H. Rubbo, and V. O'Donnell Nitric oxide, peroxynitrite and lipoxygenase in atherogenesis: mechanistic insights Toxicology 208 2005 305 317
-
(2005)
Toxicology
, vol.208
, pp. 305-317
-
-
Rubbo, H.1
O'Donnell, V.2
-
99
-
-
0030993186
-
A kinetic model for the interaction of nitric oxide with a mammalian lipoxygenase
-
H.G. Holzhutter, R. Wiesner, J. Rathmann, R. Stosser, and H. Kuhn A kinetic model for the interaction of nitric oxide with a mammalian lipoxygenase Eur J Biochem 245 1997 608 616
-
(1997)
Eur J Biochem
, vol.245
, pp. 608-616
-
-
Holzhutter, H.G.1
Wiesner, R.2
Rathmann, J.3
Stosser, R.4
Kuhn, H.5
-
100
-
-
0034933878
-
Catalytic consumption of nitric oxide by 12/15-lipoxygenase: Inhibition of monocyte soluble guanylate cyclase activation
-
M.J. Coffey, R. Natarajan, P.H. Chumley, B. Coles, P.R. Thimmalapura, and M. Nowell Catalytic consumption of nitric oxide by 12/15-lipoxygenase: inhibition of monocyte soluble guanylate cyclase activation Proc Natl Acad Sci USA 98 2001 8006 8011
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 8006-8011
-
-
Coffey, M.J.1
Natarajan, R.2
Chumley, P.H.3
Coles, B.4
Thimmalapura, P.R.5
Nowell, M.6
-
101
-
-
14644426612
-
Elevated endothelial nitric oxide bioactivity and resistance to angiotensin-dependent hypertension in 12/15-lipoxygenase knockout mice
-
P.B. Anning, B. Coles, A. Bermudez-Fajardo, P.E. Martin, B.S. Levison, and S.L. Hazen Elevated endothelial nitric oxide bioactivity and resistance to angiotensin-dependent hypertension in 12/15-lipoxygenase knockout mice Am J Pathol 166 2005 653 662
-
(2005)
Am J Pathol
, vol.166
, pp. 653-662
-
-
Anning, P.B.1
Coles, B.2
Bermudez-Fajardo, A.3
Martin, P.E.4
Levison, B.S.5
Hazen, S.L.6
-
102
-
-
0037687982
-
Chronic hypoxia activates lung 15-lipoxygenase, which catalyzes production of 15-HETE and enhances constriction in neonatal rabbit pulmonary arteries
-
D. Zhu, M. Medhora, W.B. Campbell, N. Spitzbarth, J.E. Baker, and E.R. Jacobs Chronic hypoxia activates lung 15-lipoxygenase, which catalyzes production of 15-HETE and enhances constriction in neonatal rabbit pulmonary arteries Circ Res. 92 2003 992 1000
-
(2003)
Circ Res.
, vol.92
, pp. 992-1000
-
-
Zhu, D.1
Medhora, M.2
Campbell, W.B.3
Spitzbarth, N.4
Baker, J.E.5
Jacobs, E.R.6
-
104
-
-
0032553415
-
Identification of the 11, 14, 15- and 11, 12, 15-trihydroxyeicosatrienoic acids as endothelium-derived relaxing factors of rabbit aorta
-
S.L. Pfister, N. Spitzbarth, K. Nithipatikom, W.S. Edgemond, J.R. Falck, and W.B. Campbell Identification of the 11, 14, 15- and 11, 12, 15-trihydroxyeicosatrienoic acids as endothelium-derived relaxing factors of rabbit aorta J Biol Chem 273 1998 30879 30887
-
(1998)
J Biol Chem
, vol.273
, pp. 30879-30887
-
-
Pfister, S.L.1
Spitzbarth, N.2
Nithipatikom, K.3
Edgemond, W.S.4
Falck, J.R.5
Campbell, W.B.6
-
105
-
-
71449107550
-
Identification of 13-hydroxy-14, 15-epoxyeicosatrienoic acid as an acid-stable endothelium-derived hyperpolarizing factor in rabbit arteries
-
Y. Chawengsub, K.M. Gauthier, K. Nithipatikom, B.D. Hammock, J.R. Falck, and D. Narsimhaswamy Identification of 13-hydroxy-14, 15-epoxyeicosatrienoic acid as an acid-stable endothelium-derived hyperpolarizing factor in rabbit arteries J Biol Chem 284 2009 31280 31290
-
(2009)
J Biol Chem
, vol.284
, pp. 31280-31290
-
-
Chawengsub, Y.1
Gauthier, K.M.2
Nithipatikom, K.3
Hammock, B.D.4
Falck, J.R.5
Narsimhaswamy, D.6
-
106
-
-
0023851897
-
Eicosanoid metabolism in cerebromicrovascular endothelium
-
S.A. Moore, A.A. Spector, and M.N. Hart Eicosanoid metabolism in cerebromicrovascular endothelium Am J Physiol 254 1988 C37 C44
-
(1988)
Am J Physiol
, vol.254
-
-
Moore, S.A.1
Spector, A.A.2
Hart, M.N.3
-
107
-
-
6644226179
-
12-lipoxygenase in porcine coronary microcirculation: Implications for coronary vasoregulation
-
M.H. Zink, C.L. Oltman, T. Lu, P.V. Katakam, T.L. Kaduce, and H. Lee 12-lipoxygenase in porcine coronary microcirculation: implications for coronary vasoregulation Am J Physiol Heart Circ Physiol 280 2001 H693 H704
-
(2001)
Am J Physiol Heart Circ Physiol
, vol.280
-
-
Zink, M.H.1
Oltman, C.L.2
Lu, T.3
Katakam, P.V.4
Kaduce, T.L.5
Lee, H.6
-
108
-
-
0037214546
-
Arachidonic acid-induced vasodilation of rat small mesenteric arteries is lipoxygenase-dependent
-
A.W. Miller, P.V. Katakam, H.C. Lee, C.D. Tulbert, D.W. Busija, and N.L. Weintraub Arachidonic acid-induced vasodilation of rat small mesenteric arteries is lipoxygenase-dependent J Pharmacol Exp Ther 304 2003 139 144
-
(2003)
J Pharmacol Exp Ther
, vol.304
, pp. 139-144
-
-
Miller, A.W.1
Katakam, P.V.2
Lee, H.C.3
Tulbert, C.D.4
Busija, D.W.5
Weintraub, N.L.6
-
109
-
-
0034809639
-
Arachidonate dilates basilar artery by lipoxygenase-dependent mechanism and activation of K(+) channels
-
F.M. Faraci, C.G. Sobey, S. Chrissobolis, D.D. Lund, D.D. Heistad, and N.L. Weintraub Arachidonate dilates basilar artery by lipoxygenase-dependent mechanism and activation of K(+) channels Am J Physiol Regul Integr Comp Physiol 281 2001 R246 R253
-
(2001)
Am J Physiol Regul Integr Comp Physiol
, vol.281
-
-
Faraci, F.M.1
Sobey, C.G.2
Chrissobolis, S.3
Lund, D.D.4
Heistad, D.D.5
Weintraub, N.L.6
-
110
-
-
33644849675
-
Epoxyeicosatrienoic and dihydroxyeicosatrienoic acids dilate human coronary arterioles via BK(Ca) channels: Implications for soluble epoxide hydrolase inhibition
-
B.T. Larsen, H. Miura, O.A. Hatoum, W.B. Campbell, B.D. Hammock, and D.C. Zeldin Epoxyeicosatrienoic and dihydroxyeicosatrienoic acids dilate human coronary arterioles via BK(Ca) channels: implications for soluble epoxide hydrolase inhibition Am J Physiol Heart Circ Physiol 290 2006 H491 H499
-
(2006)
Am J Physiol Heart Circ Physiol
, vol.290
-
-
Larsen, B.T.1
Miura, H.2
Hatoum, O.A.3
Campbell, W.B.4
Hammock, B.D.5
Zeldin, D.C.6
-
112
-
-
0037757519
-
Metabolism of 12-hydroperoxyeicosatetraenoic acid to vasodilatory trioxilin C3 by rabbit aorta
-
S.L. Pfister, N. Spitzbarth, K. Nithipatikom, J.R. Falck, and W.B. Campbell Metabolism of 12-hydroperoxyeicosatetraenoic acid to vasodilatory trioxilin C3 by rabbit aorta Biochim Biophys Acta 1622 2003 6 13
-
(2003)
Biochim Biophys Acta
, vol.1622
, pp. 6-13
-
-
Pfister, S.L.1
Spitzbarth, N.2
Nithipatikom, K.3
Falck, J.R.4
Campbell, W.B.5
-
113
-
-
0025767695
-
Hepoxilin A3 (HxA3) is formed by the rat aorta and is metabolized into HxA3-C, a glutathione conjugate
-
O. Laneuville, E.J. Corey, R. Couture, and C.R. Pace-Asciak Hepoxilin A3 (HxA3) is formed by the rat aorta and is metabolized into HxA3-C, a glutathione conjugate Biochim Biophys Acta 1084 1991 60 68
-
(1991)
Biochim Biophys Acta
, vol.1084
, pp. 60-68
-
-
Laneuville, O.1
Corey, E.J.2
Couture, R.3
Pace-Asciak, C.R.4
-
114
-
-
0028349403
-
Lipoxin biosynthesis and its impact in inflammatory and vascular events
-
C.N. Serhan Lipoxin biosynthesis and its impact in inflammatory and vascular events Biochim Biophys Acta 1212 1994 1 25
-
(1994)
Biochim Biophys Acta
, vol.1212
, pp. 1-25
-
-
Serhan, C.N.1
-
115
-
-
0023612099
-
The mitogenic effect of 15- and 12-hydroxyeicosatetraenoic acid on endothelial cells may be mediated via diacylglycerol kinase inhibition
-
B.N. Setty, J.E. Graeber, and M.J. Stuart The mitogenic effect of 15- and 12-hydroxyeicosatetraenoic acid on endothelial cells may be mediated via diacylglycerol kinase inhibition J Biol Chem 262 1987 17613 17622
-
(1987)
J Biol Chem
, vol.262
, pp. 17613-17622
-
-
Setty, B.N.1
Graeber, J.E.2
Stuart, M.J.3
-
116
-
-
0028589154
-
Activation of mitogen-activated protein kinases by arachidonic acid and its metabolites in vascular smooth muscle cells
-
G.N. Rao, A.S. Baas, W.C. Glasgow, T.E. Eling, M.S. Runge, and R.W. Alexander Activation of mitogen-activated protein kinases by arachidonic acid and its metabolites in vascular smooth muscle cells J Biol Chem 269 1994 32586 32591
-
(1994)
J Biol Chem
, vol.269
, pp. 32586-32591
-
-
Rao, G.N.1
Baas, A.S.2
Glasgow, W.C.3
Eling, T.E.4
Runge, M.S.5
Alexander, R.W.6
-
117
-
-
1842715005
-
Regulation of monocyte chemoattractant protein-1 by the oxidized lipid, 13-hydroperoxyoctadecadienoic acid, in vascular smooth muscle cells via nuclear factor-kappa B (NF-kappa B)
-
R.S. Dwarakanath, S. Sahar, M.A. Reddy, D. Castanotto, J.J. Rossi, and R. Natarajan Regulation of monocyte chemoattractant protein-1 by the oxidized lipid, 13-hydroperoxyoctadecadienoic acid, in vascular smooth muscle cells via nuclear factor-kappa B (NF-kappa B) J Mol Cell Cardiol 36 2004 585 595
-
(2004)
J Mol Cell Cardiol
, vol.36
, pp. 585-595
-
-
Dwarakanath, R.S.1
Sahar, S.2
Reddy, M.A.3
Castanotto, D.4
Rossi, J.J.5
Natarajan, R.6
-
118
-
-
73949150404
-
ROCK pathway participates in the processes that 15- hydroxyeicosatetraenoic acid (15-HETE) mediated the pulmonary vascular remodeling induced by hypoxia in rat
-
J. Ma, S. Liang, Z. Wang, L. Zhang, J. Jiang, and J. Zheng ROCK pathway participates in the processes that 15-hydroxyeicosatetraenoic acid (15-HETE) mediated the pulmonary vascular remodeling induced by hypoxia in rat J Cell Physiol 222 2010 82 94
-
(2010)
J Cell Physiol
, vol.222
, pp. 82-94
-
-
Ma, J.1
Liang, S.2
Wang, Z.3
Zhang, L.4
Jiang, J.5
Zheng, J.6
-
119
-
-
0028130811
-
13-HODE increases intracellular calcium in vascular smooth muscle cells
-
L.L. Stoll, M.R. Morland, and A.A. Spector 13-HODE increases intracellular calcium in vascular smooth muscle cells Am J Physiol 266 1994 C990 C996
-
(1994)
Am J Physiol
, vol.266
-
-
Stoll, L.L.1
Morland, M.R.2
Spector, A.A.3
-
120
-
-
0035853386
-
Adenoviral delivery of a leukocyte-type 12 lipoxygenase ribozyme inhibits effects of glucose and platelet-derived growth factor in vascular endothelial and smooth muscle cells
-
M.K. Patricia, R. Natarajan, A.N. Dooley, F. Hernandez, J.L. Gu, and J.A. Berliner Adenoviral delivery of a leukocyte-type 12 lipoxygenase ribozyme inhibits effects of glucose and platelet-derived growth factor in vascular endothelial and smooth muscle cells Circ Res 88 2001 659 665
-
(2001)
Circ Res
, vol.88
, pp. 659-665
-
-
Patricia, M.K.1
Natarajan, R.2
Dooley, A.N.3
Hernandez, F.4
Gu, J.L.5
Berliner, J.A.6
-
121
-
-
66349103988
-
CREB-mediated IL-6 expression is required for 15(S)- hydroxyeicosatetraenoic acid-induced vascular smooth muscle cell migration
-
K.R. Chava, M. Karpurapu, D. Wang, M. Bhanoori, V. Kundumani-Sridharan, and Q. Zhang CREB-mediated IL-6 expression is required for 15(S)- hydroxyeicosatetraenoic acid-induced vascular smooth muscle cell migration Arterioscler Thromb Vasc Biol 29 2009 809 815
-
(2009)
Arterioscler Thromb Vasc Biol
, vol.29
, pp. 809-815
-
-
Chava, K.R.1
Karpurapu, M.2
Wang, D.3
Bhanoori, M.4
Kundumani-Sridharan, V.5
Zhang, Q.6
-
122
-
-
71449108959
-
Src-dependent STAT-3-mediated expression of monocyte chemoattractant protein-1 is required for 15(S)-hydroxyeicosatetraenoic acid-induced vascular smooth muscle cell migration
-
H.S. Potula, D. Wang, D.V. Quyen, N.K. Singh, V. Kundumani-Sridharan, and M. Karpurapu Src-dependent STAT-3-mediated expression of monocyte chemoattractant protein-1 is required for 15(S)-hydroxyeicosatetraenoic acid-induced vascular smooth muscle cell migration J Biol Chem 284 2009 31142 31155
-
(2009)
J Biol Chem
, vol.284
, pp. 31142-31155
-
-
Potula, H.S.1
Wang, D.2
Quyen, D.V.3
Singh, N.K.4
Kundumani-Sridharan, V.5
Karpurapu, M.6
-
123
-
-
0038458816
-
Reduced growth factor responses in vascular smooth muscle cells derived from 12/15-lipoxygenase-deficient mice
-
M.A. Reddy, Y.S. Kim, L. Lanting, and R. Natarajan Reduced growth factor responses in vascular smooth muscle cells derived from 12/15-lipoxygenase- deficient mice Hypertension 41 2003 1294 1300
-
(2003)
Hypertension
, vol.41
, pp. 1294-1300
-
-
Reddy, M.A.1
Kim, Y.S.2
Lanting, L.3
Natarajan, R.4
-
124
-
-
74849085099
-
15-HETE protects rat pulmonary arterial smooth muscle cells from apoptosis via the PI3K/Akt pathway
-
S. Wang, Y. Wang, J. Jiang, R. Wang, L. Li, and Z. Qiu 15-HETE protects rat pulmonary arterial smooth muscle cells from apoptosis via the PI3K/Akt pathway Prostaglandins Other Lipid Mediat 91 2010 51 60
-
(2010)
Prostaglandins Other Lipid Mediat
, vol.91
, pp. 51-60
-
-
Wang, S.1
Wang, Y.2
Jiang, J.3
Wang, R.4
Li, L.5
Qiu, Z.6
-
125
-
-
77955454197
-
Review: Potential role of the lipoxygenase derived lipid mediators in atherosclerosis: Leukotrienes, lipoxins and resolvins
-
Hersberger M. Review: Potential role of the lipoxygenase derived lipid mediators in atherosclerosis: leukotrienes, lipoxins and resolvins. Clin Chem Lab Med. 2010.
-
(2010)
Clin Chem Lab Med
-
-
Hersberger, M.1
-
126
-
-
0033812812
-
Overexpression of 15-lipoxygenase in vascular endothelium accelerates early atherosclerosis in LDL receptor-deficient mice
-
D. Harats, A. Shaish, J. George, M. Mulkins, H. Kurihara, and H. Levkovitz Overexpression of 15-lipoxygenase in vascular endothelium accelerates early atherosclerosis in LDL receptor-deficient mice Arterioscler Thromb Vasc Biol 20 2000 2100 2105
-
(2000)
Arterioscler Thromb Vasc Biol
, vol.20
, pp. 2100-2105
-
-
Harats, D.1
Shaish, A.2
George, J.3
Mulkins, M.4
Kurihara, H.5
Levkovitz, H.6
-
127
-
-
0029829533
-
Macrophage-mediated 15-lipoxygenase expression protects against atherosclerosis development
-
J. Shen, E. Herderick, J.F. Cornhill, E. Zsigmond, H.S. Kim, and H. Kuhn Macrophage-mediated 15-lipoxygenase expression protects against atherosclerosis development J Clin Invest 98 1996 2201 2208
-
(1996)
J Clin Invest
, vol.98
, pp. 2201-2208
-
-
Shen, J.1
Herderick, E.2
Cornhill, J.F.3
Zsigmond, E.4
Kim, H.S.5
Kuhn, H.6
-
128
-
-
0036893747
-
Transient experimental anemia in cholesterol-fed rabbits induces systemic overexpression of the reticulocyte-type 15-lipoxygenase and protects from aortic lipid deposition
-
F. Trebus, D. Heydeck, I. Schimke, C. Gerth, and H. Kuhn Transient experimental anemia in cholesterol-fed rabbits induces systemic overexpression of the reticulocyte-type 15-lipoxygenase and protects from aortic lipid deposition Prostaglandins Leukot Essent Fatty Acids 67 2002 419 428
-
(2002)
Prostaglandins Leukot Essent Fatty Acids
, vol.67
, pp. 419-428
-
-
Trebus, F.1
Heydeck, D.2
Schimke, I.3
Gerth, C.4
Kuhn, H.5
-
129
-
-
0032752579
-
Disruption of the 12/15-lipoxygenase gene diminishes atherosclerosis in apo E-deficient mice
-
T. Cyrus, J.L. Witztum, D.J. Rader, R. Tangirala, S. Fazio, and M.F. Linton Disruption of the 12/15-lipoxygenase gene diminishes atherosclerosis in apo E-deficient mice J Clin Invest 103 1999 1597 1604
-
(1999)
J Clin Invest
, vol.103
, pp. 1597-1604
-
-
Cyrus, T.1
Witztum, J.L.2
Rader, D.J.3
Tangirala, R.4
Fazio, S.5
Linton, M.F.6
-
130
-
-
0035826892
-
Absence of 12/15-lipoxygenase expression decreases lipid peroxidation and atherogenesis in apolipoprotein e-deficient mice
-
T. Cyrus, D. Pratico, L. Zhao, J.L. Witztum, D.J. Rader, and J. Rokach Absence of 12/15-lipoxygenase expression decreases lipid peroxidation and atherogenesis in apolipoprotein e-deficient mice Circulation 103 2001 2277 2282
-
(2001)
Circulation
, vol.103
, pp. 2277-2282
-
-
Cyrus, T.1
Pratico, D.2
Zhao, L.3
Witztum, J.L.4
Rader, D.J.5
Rokach, J.6
-
131
-
-
20844446795
-
Critical role of macrophage 12/15-lipoxygenase for atherosclerosis in apolipoprotein E-deficient mice
-
Y. Huo, L. Zhao, M.C. Hyman, P. Shashkin, B.L. Harry, and T. Burcin Critical role of macrophage 12/15-lipoxygenase for atherosclerosis in apolipoprotein E-deficient mice Circulation 110 2004 2024 2031
-
(2004)
Circulation
, vol.110
, pp. 2024-2031
-
-
Huo, Y.1
Zhao, L.2
Hyman, M.C.3
Shashkin, P.4
Harry, B.L.5
Burcin, T.6
-
132
-
-
24344510350
-
Anti-inflammatory circuitry: Lipoxin, aspirin-triggered lipoxins and their receptor ALX
-
N. Chiang, M. Arita, and C.N. Serhan Anti-inflammatory circuitry: lipoxin, aspirin-triggered lipoxins and their receptor ALX Prostaglandins Leukot Essent Fatty Acids 73 2005 163 177
-
(2005)
Prostaglandins Leukot Essent Fatty Acids
, vol.73
, pp. 163-177
-
-
Chiang, N.1
Arita, M.2
Serhan, C.N.3
-
133
-
-
68949116297
-
Dual 12/15- and 5-lipoxygenase deficiency in macrophages alters arachidonic acid metabolism and attenuates peritonitis and atherosclerosis in ApoE knock-out mice
-
D. Poeckel, K.A. Zemski Berry, R.C. Murphy, and C.D. Funk Dual 12/15- and 5-lipoxygenase deficiency in macrophages alters arachidonic acid metabolism and attenuates peritonitis and atherosclerosis in ApoE knock-out mice J Biol Chem 284 2009 21077 21089
-
(2009)
J Biol Chem
, vol.284
, pp. 21077-21089
-
-
Poeckel, D.1
Zemski Berry, K.A.2
Murphy, R.C.3
Funk, C.D.4
-
134
-
-
0027478121
-
Oxygenation of lipoproteins by mammalian lipoxygenases
-
J. Belkner, R. Wiesner, J. Rathman, J. Barnett, E. Sigal, and H. Kuhn Oxygenation of lipoproteins by mammalian lipoxygenases Eur J Biochem 213 1993 251 261
-
(1993)
Eur J Biochem
, vol.213
, pp. 251-261
-
-
Belkner, J.1
Wiesner, R.2
Rathman, J.3
Barnett, J.4
Sigal, E.5
Kuhn, H.6
-
135
-
-
0025756633
-
Evidence for a dominant role of lipoxygenase(s) in the oxidation of LDL by mouse peritoneal macrophages
-
S.M. Rankin, S. Parthasarathy, and D. Steinberg Evidence for a dominant role of lipoxygenase(s) in the oxidation of LDL by mouse peritoneal macrophages J Lipid Res 32 1991 449 456
-
(1991)
J Lipid Res
, vol.32
, pp. 449-456
-
-
Rankin, S.M.1
Parthasarathy, S.2
Steinberg, D.3
-
136
-
-
0031471792
-
Fibroblasts that overexpress 15-lipoxygenase generate bioactive and minimally modified LDL
-
F. Sigari, C. Lee, J.L. Witztum, and P.D. Reaven Fibroblasts that overexpress 15-lipoxygenase generate bioactive and minimally modified LDL Arterioscler Thromb Vasc Biol 17 1997 3639 3645
-
(1997)
Arterioscler Thromb Vasc Biol
, vol.17
, pp. 3639-3645
-
-
Sigari, F.1
Lee, C.2
Witztum, J.L.3
Reaven, P.D.4
-
138
-
-
0037968682
-
Low density lipoprotein receptor-related protein-mediated membrane translocation of 12/15-lipoxygenase is required for oxidation of low density lipoprotein by macrophages
-
H. Zhu, Y. Takahashi, W. Xu, H. Kawajiri, T. Murakami, and M. Yamamoto Low density lipoprotein receptor-related protein-mediated membrane translocation of 12/15-lipoxygenase is required for oxidation of low density lipoprotein by macrophages J Biol Chem 278 2003 13350 13355
-
(2003)
J Biol Chem
, vol.278
, pp. 13350-13355
-
-
Zhu, H.1
Takahashi, Y.2
Xu, W.3
Kawajiri, H.4
Murakami, T.5
Yamamoto, M.6
-
139
-
-
27544444125
-
Selective uptake and efflux of cholesteryl linoleate in LDL by macrophages expressing 12/15-lipoxygenase
-
Y. Takahashi, H. Zhu, W. Xu, T. Murakami, T. Iwasaki, and H. Hattori Selective uptake and efflux of cholesteryl linoleate in LDL by macrophages expressing 12/15-lipoxygenase Biochem Biophys Res Commun 338 2005 128 135
-
(2005)
Biochem Biophys Res Commun
, vol.338
, pp. 128-135
-
-
Takahashi, Y.1
Zhu, H.2
Xu, W.3
Murakami, T.4
Iwasaki, T.5
Hattori, H.6
-
140
-
-
53449092580
-
12/15-Lipoxygenase activity increases the degradation of macrophage ATP-binding cassette transporter G1
-
M.H. Nagelin, S. Srinivasan, J. Lee, J.L. Nadler, and C.C. Hedrick 12/15-Lipoxygenase activity increases the degradation of macrophage ATP-binding cassette transporter G1 Arterioscler Thromb Vasc Biol 28 2008 1811 1819
-
(2008)
Arterioscler Thromb Vasc Biol
, vol.28
, pp. 1811-1819
-
-
Nagelin, M.H.1
Srinivasan, S.2
Lee, J.3
Nadler, J.L.4
Hedrick, C.C.5
-
141
-
-
71449105303
-
Murine 12/15-lipoxygenase regulates ATP-binding cassette transporter G1 protein degradation through p38- and JNK2-dependent pathways
-
M.H. Nagelin, S. Srinivasan, J.L. Nadler, and C.C. Hedrick Murine 12/15-lipoxygenase regulates ATP-binding cassette transporter G1 protein degradation through p38- and JNK2-dependent pathways J Biol Chem 284 2009 31303 31314
-
(2009)
J Biol Chem
, vol.284
, pp. 31303-31314
-
-
Nagelin, M.H.1
Srinivasan, S.2
Nadler, J.L.3
Hedrick, C.C.4
-
142
-
-
0042737910
-
Low high-density lipoprotein cholesterol: Physiological background, clinical importance and drug treatment
-
M. Hersberger, and A. von Eckardstein Low high-density lipoprotein cholesterol: physiological background, clinical importance and drug treatment Drugs 63 2003 1907 1945
-
(2003)
Drugs
, vol.63
, pp. 1907-1945
-
-
Hersberger, M.1
Von Eckardstein, A.2
-
144
-
-
33646128719
-
15-Lipoxygenase-mediated modification of high-density lipoproteins impairs SR-BI- and ABCA1-dependent cholesterol efflux from macrophages
-
A. Pirillo, P. Uboldi, H. Kuhn, and A.L. Catapano 15-Lipoxygenase- mediated modification of high-density lipoproteins impairs SR-BI- and ABCA1-dependent cholesterol efflux from macrophages Biochim Biophys Acta 1761 2006 292 300
-
(2006)
Biochim Biophys Acta
, vol.1761
, pp. 292-300
-
-
Pirillo, A.1
Uboldi, P.2
Kuhn, H.3
Catapano, A.L.4
-
145
-
-
53149097776
-
The 15-lipoxygenase-modified high density lipoproteins 3 fail to inhibit the TNF-alpha-induced inflammatory response in human endothelial cells
-
A. Pirillo, P. Uboldi, C. Bolego, H. Kuhn, and A.L. Catapano The 15-lipoxygenase-modified high density lipoproteins 3 fail to inhibit the TNF-alpha-induced inflammatory response in human endothelial cells J Immunol 181 2008 2821 2830
-
(2008)
J Immunol
, vol.181
, pp. 2821-2830
-
-
Pirillo, A.1
Uboldi, P.2
Bolego, C.3
Kuhn, H.4
Catapano, A.L.5
-
146
-
-
0028998879
-
A leukocyte type of 12-lipoxygenase is expressed in human vascular and mononuclear cells. Evidence for upregulation by angiotensin II
-
J.A. Kim, J.L. Gu, R. Natarajan, J.A. Berliner, and J.L. Nadler A leukocyte type of 12-lipoxygenase is expressed in human vascular and mononuclear cells. Evidence for upregulation by angiotensin II Arterioscler Thromb Vasc Biol 15 1995 942 948
-
(1995)
Arterioscler Thromb Vasc Biol
, vol.15
, pp. 942-948
-
-
Kim, J.A.1
Gu, J.L.2
Natarajan, R.3
Berliner, J.A.4
Nadler, J.L.5
-
147
-
-
10744233434
-
12/15-Lipoxygenase activity mediates inflammatory monocyte/endothelial interactions and atherosclerosis in vivo
-
K.B. Reilly, S. Srinivasan, M.E. Hatley, M.K. Patricia, J. Lannigan, and D.T. Bolick 12/15-Lipoxygenase activity mediates inflammatory monocyte/endothelial interactions and atherosclerosis in vivo J Biol Chem 279 2004 9440 9450
-
(2004)
J Biol Chem
, vol.279
, pp. 9440-9450
-
-
Reilly, K.B.1
Srinivasan, S.2
Hatley, M.E.3
Patricia, M.K.4
Lannigan, J.5
Bolick, D.T.6
-
148
-
-
0342281480
-
Transient overexpression of human 15-lipoxygenase in aortic endothelial cells enhances tumor necrosis factor-induced vascular cell adhesion molecule-1 gene expression
-
J. Wolle, K.A. Welch, L.J. Devall, J.A. Cornicelli, and U. Saxena Transient overexpression of human 15-lipoxygenase in aortic endothelial cells enhances tumor necrosis factor-induced vascular cell adhesion molecule-1 gene expression Biochem Biophys Res Commun 220 1996 310 314
-
(1996)
Biochem Biophys Res Commun
, vol.220
, pp. 310-314
-
-
Wolle, J.1
Welch, K.A.2
Devall, L.J.3
Cornicelli, J.A.4
Saxena, U.5
-
149
-
-
0033086392
-
High expression of human 15-lipoxygenase induces NF-kappaB-mediated expression of vascular cell adhesion molecule 1, intercellular adhesion molecule 1, and T-cell adhesion on human endothelial cells
-
H. Viita, C.K. Sen, S. Roy, T. Siljamaki, T. Nikkari, and S. Yla-Herttuala High expression of human 15-lipoxygenase induces NF-kappaB-mediated expression of vascular cell adhesion molecule 1, intercellular adhesion molecule 1, and T-cell adhesion on human endothelial cells Antioxid Redox Signal 1 1999 83 96
-
(1999)
Antioxid Redox Signal
, vol.1
, pp. 83-96
-
-
Viita, H.1
Sen, C.K.2
Roy, S.3
Siljamaki, T.4
Nikkari, T.5
Yla-Herttuala, S.6
-
150
-
-
27644571486
-
12/15-lipoxygenase regulates intercellular adhesion molecule-1 expression and monocyte adhesion to endothelium through activation of RhoA and nuclear factor-kappaB
-
D.T. Bolick, A.W. Orr, A. Whetzel, S. Srinivasan, M.E. Hatley, and M.A. Schwartz 12/15-lipoxygenase regulates intercellular adhesion molecule-1 expression and monocyte adhesion to endothelium through activation of RhoA and nuclear factor-kappaB Arterioscler Thromb Vasc Biol 25 2005 2301 2307
-
(2005)
Arterioscler Thromb Vasc Biol
, vol.25
, pp. 2301-2307
-
-
Bolick, D.T.1
Orr, A.W.2
Whetzel, A.3
Srinivasan, S.4
Hatley, M.E.5
Schwartz, M.A.6
-
151
-
-
20844462708
-
Hypoxia increases LDL oxidation and expression of 15-lipoxygenase-2 in human macrophages
-
E.K. Rydberg, A. Krettek, C. Ullstrom, K. Ekstrom, P.A. Svensson, and L.M. Carlsson Hypoxia increases LDL oxidation and expression of 15-lipoxygenase-2 in human macrophages Arterioscler Thromb Vasc Biol 24 2004 2040 2045
-
(2004)
Arterioscler Thromb Vasc Biol
, vol.24
, pp. 2040-2045
-
-
Rydberg, E.K.1
Krettek, A.2
Ullstrom, C.3
Ekstrom, K.4
Svensson, P.A.5
Carlsson, L.M.6
-
152
-
-
45449120515
-
15-Lipoxygenase-2 expression in human macrophages induces chemokine secretion and T cell migration
-
K.N. Danielsson, E.K. Rydberg, M. Ingelsten, L.M. Akyurek, P. Jirholt, and C. Ullstrom 15-Lipoxygenase-2 expression in human macrophages induces chemokine secretion and T cell migration Atherosclerosis 199 2008 34 40
-
(2008)
Atherosclerosis
, vol.199
, pp. 34-40
-
-
Danielsson, K.N.1
Rydberg, E.K.2
Ingelsten, M.3
Akyurek, L.M.4
Jirholt, P.5
Ullstrom, C.6
-
153
-
-
0027270732
-
Transmembrane signaling in human polymorphonuclear neutrophils: 15(S)-hydroxy-(5Z, 8Z, 11Z, 13E)-eicosatetraenoic acid modulates receptor agonist-triggered cell activation
-
R.J. Smith, J.M. Justen, E.G. Nidy, L.M. Sam, and J.E. Bleasdale Transmembrane signaling in human polymorphonuclear neutrophils: 15(S)-hydroxy-(5Z, 8Z, 11Z, 13E)-eicosatetraenoic acid modulates receptor agonist-triggered cell activation Proc Natl Acad Sci USA 90 1993 7270 7274
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 7270-7274
-
-
Smith, R.J.1
Justen, J.M.2
Nidy, E.G.3
Sam, L.M.4
Bleasdale, J.E.5
-
154
-
-
0028169226
-
15-Hydroxyeicosatetraenoic acid inhibits neutrophil migration across cytokine-activated endothelium
-
S. Takata, A. Papayianni, M. Matsubara, W. Jimenez, P.H. Pronovost, and H.R. Brady 15-Hydroxyeicosatetraenoic acid inhibits neutrophil migration across cytokine-activated endothelium Am J Pathol 145 1994 541 549
-
(1994)
Am J Pathol
, vol.145
, pp. 541-549
-
-
Takata, S.1
Papayianni, A.2
Matsubara, M.3
Jimenez, W.4
Pronovost, P.H.5
Brady, H.R.6
-
155
-
-
0028273498
-
Remodeling of neutrophil phospholipids with 15(S)-hydroxyeicosatetraenoic acid inhibits leukotriene B4-induced neutrophil migration across endothelium
-
S. Takata, M. Matsubara, P.G. Allen, P.A. Janmey, C.N. Serhan, and H.R.
-
(1994)
J Clin Invest
, vol.93
, pp. 499-508
-
-
Takata, S.1
Matsubara, M.2
Allen, P.G.3
Janmey, P.A.4
Serhan, C.N.5
Brady, H.R.6
-
156
-
-
0027265208
-
Localization of 13-hydroxyoctadecadienoic acid and the vitronectin receptor in human endothelial cells and endothelial cell/platelet interactions in vitro
-
M.R. Buchanan, M.C. Bertomeu, T.A. Haas, F.W. Orr, and L.L. Eltringham-Smith Localization of 13-hydroxyoctadecadienoic acid and the vitronectin receptor in human endothelial cells and endothelial cell/platelet interactions in vitro Blood 81 1993 3303 3312
-
(1993)
Blood
, vol.81
, pp. 3303-3312
-
-
Buchanan, M.R.1
Bertomeu, M.C.2
Haas, T.A.3
Orr, F.W.4
Eltringham-Smith, L.L.5
-
157
-
-
0031886864
-
The peroxisome proliferator-activated receptor-gamma is a negative regulator of macrophage activation
-
M. Ricote, A.C. Li, T.M. Willson, C.J. Kelly, and C.K. Glass The peroxisome proliferator-activated receptor-gamma is a negative regulator of macrophage activation Nature 391 1998 79 82
-
(1998)
Nature
, vol.391
, pp. 79-82
-
-
Ricote, M.1
Li, A.C.2
Willson, T.M.3
Kelly, C.J.4
Glass, C.K.5
-
158
-
-
0036160759
-
Role of 12-lipoxygenase and oxidant stress in hyperglycaemia-induced acceleration of atherosclerosis in a diabetic pig model
-
R. Natarajan, R.G. Gerrity, J.L. Gu, L. Lanting, L. Thomas, and J.L. Nadler Role of 12-lipoxygenase and oxidant stress in hyperglycaemia-induced acceleration of atherosclerosis in a diabetic pig model Diabetologia 45 2002 125 133
-
(2002)
Diabetologia
, vol.45
, pp. 125-133
-
-
Natarajan, R.1
Gerrity, R.G.2
Gu, J.L.3
Lanting, L.4
Thomas, L.5
Nadler, J.L.6
-
159
-
-
33644875634
-
Activation of the 12-lipoxygenase and signal transducer and activator of transcription pathway during neointima formation in a model of the metabolic syndrome
-
H. Pei, J. Gu, P.R. Thimmalapura, A. Mison, and J.L. Nadler Activation of the 12-lipoxygenase and signal transducer and activator of transcription pathway during neointima formation in a model of the metabolic syndrome Am J Physiol Endocrinol Metab 290 2006 E92 E102
-
(2006)
Am J Physiol Endocrinol Metab
, vol.290
-
-
Pei, H.1
Gu, J.2
Thimmalapura, P.R.3
Mison, A.4
Nadler, J.L.5
-
160
-
-
0029006970
-
Ribozyme-mediated inhibition of expression of leukocyte-type 12-lipoxygenase in porcine aortic vascular smooth muscle cells
-
J.L. Gu, D. Veerapanane, J. Rossi, R. Natarajan, L. Thomas, and J. Nadler Ribozyme-mediated inhibition of expression of leukocyte-type 12-lipoxygenase in porcine aortic vascular smooth muscle cells Circ Res 77 1995 14 20
-
(1995)
Circ Res
, vol.77
, pp. 14-20
-
-
Gu, J.L.1
Veerapanane, D.2
Rossi, J.3
Natarajan, R.4
Thomas, L.5
Nadler, J.6
-
161
-
-
0038640370
-
Overexpression of 12-lipoxygenase and cardiac fibroblast hypertrophy
-
Y. Wen, J. Gu, X. Peng, G. Zhang, and J. Nadler Overexpression of 12-lipoxygenase and cardiac fibroblast hypertrophy Trends Cardiovasc Med 13 2003 129 136
-
(2003)
Trends Cardiovasc Med
, vol.13
, pp. 129-136
-
-
Wen, Y.1
Gu, J.2
Peng, X.3
Zhang, G.4
Nadler, J.5
-
162
-
-
0024329942
-
Lipoxin A4 and lipoxin B4 inhibit chemotactic responses of human neutrophils stimulated by leukotriene B4 and N-formyl-l-methionyl-l-leucyl-l- phenylalanine
-
T.H. Lee, C.E. Horton, U. Kyan-Aung, D. Haskard, A.E. Crea, and B.W. Spur Lipoxin A4 and lipoxin B4 inhibit chemotactic responses of human neutrophils stimulated by leukotriene B4 and N-formyl-l-methionyl-l-leucyl-l-phenylalanine Clin Sci (Lond) 77 1989 195 203
-
(1989)
Clin Sci (Lond)
, vol.77
, pp. 195-203
-
-
Lee, T.H.1
Horton, C.E.2
Kyan-Aung, U.3
Haskard, D.4
Crea, A.E.5
Spur, B.W.6
-
163
-
-
0027337719
-
Lipoxin A4 modulates transmigration of human neutrophils across intestinal epithelial monolayers
-
S.P. Colgan, C.N. Serhan, C.A. Parkos, C. Delp-Archer, and J.L. Madara Lipoxin A4 modulates transmigration of human neutrophils across intestinal epithelial monolayers J Clin Invest 92 1993 75 82
-
(1993)
J Clin Invest
, vol.92
, pp. 75-82
-
-
Colgan, S.P.1
Serhan, C.N.2
Parkos, C.A.3
Delp-Archer, C.4
Madara, J.L.5
-
164
-
-
0034651737
-
Cutting edge: Lipoxins rapidly stimulate nonphlogistic phagocytosis of apoptotic neutrophils by monocyte-derived macrophages
-
C. Godson, S. Mitchell, K. Harvey, N.A. Petasis, N. Hogg, and H.R. Brady Cutting edge: lipoxins rapidly stimulate nonphlogistic phagocytosis of apoptotic neutrophils by monocyte-derived macrophages J Immunol 164 2000 1663 1667
-
(2000)
J Immunol
, vol.164
, pp. 1663-1667
-
-
Godson, C.1
Mitchell, S.2
Harvey, K.3
Petasis, N.A.4
Hogg, N.5
Brady, H.R.6
-
165
-
-
0029671266
-
Lipoxin A4 and B4 are potent stimuli for human monocyte migration and adhesion: Selective inactivation by dehydrogenation and reduction
-
J.F. Maddox, and C.N. Serhan Lipoxin A4 and B4 are potent stimuli for human monocyte migration and adhesion: selective inactivation by dehydrogenation and reduction J Exp Med 183 1996 137 146
-
(1996)
J Exp Med
, vol.183
, pp. 137-146
-
-
Maddox, J.F.1
Serhan, C.N.2
-
166
-
-
7644231561
-
The chemokine system in diverse forms of macrophage activation and polarization
-
A. Mantovani, A. Sica, S. Sozzani, P. Allavena, A. Vecchi, and M. Locati The chemokine system in diverse forms of macrophage activation and polarization Trends Immunol 25 2004 677 686
-
(2004)
Trends Immunol
, vol.25
, pp. 677-686
-
-
Mantovani, A.1
Sica, A.2
Sozzani, S.3
Allavena, P.4
Vecchi, A.5
Locati, M.6
-
167
-
-
18544378668
-
Lipoxins, aspirin-triggered epi-lipoxins, lipoxin stable analogues, and the resolution of inflammation: Stimulation of macrophage phagocytosis of apoptotic neutrophils in vivo
-
S. Mitchell, G. Thomas, K. Harvey, D. Cottell, K. Reville, and G. Berlasconi Lipoxins, aspirin-triggered epi-lipoxins, lipoxin stable analogues, and the resolution of inflammation: stimulation of macrophage phagocytosis of apoptotic neutrophils in vivo J Am Soc Nephrol 13 2002 2497 2507
-
(2002)
J Am Soc Nephrol
, vol.13
, pp. 2497-2507
-
-
Mitchell, S.1
Thomas, G.2
Harvey, K.3
Cottell, D.4
Reville, K.5
Berlasconi, G.6
-
168
-
-
54049137639
-
Atherosclerosis: Evidence for impairment of resolution of vascular inflammation governed by specific lipid mediators
-
A.J. Merched, K. Ko, K.H. Gotlinger, C.N. Serhan, and L. Chan Atherosclerosis: evidence for impairment of resolution of vascular inflammation governed by specific lipid mediators Faseb J 22 2008 3595 3606
-
(2008)
Faseb J
, vol.22
, pp. 3595-3606
-
-
Merched, A.J.1
Ko, K.2
Gotlinger, K.H.3
Serhan, C.N.4
Chan, L.5
-
169
-
-
33947269798
-
Resolvin E1 selectively interacts with leukotriene B4 receptor BLT1 and ChemR23 to regulate inflammation
-
M. Arita, T. Ohira, Y.P. Sun, S. Elangovan, N. Chiang, and C.N. Serhan Resolvin E1 selectively interacts with leukotriene B4 receptor BLT1 and ChemR23 to regulate inflammation J Immunol 178 2007 3912 3917
-
(2007)
J Immunol
, vol.178
, pp. 3912-3917
-
-
Arita, M.1
Ohira, T.2
Sun, Y.P.3
Elangovan, S.4
Chiang, N.5
Serhan, C.N.6
-
170
-
-
41549119047
-
Omega-3 fatty acids for cardioprotection
-
J.H. Lee, J.H. O'Keefe, C.J. Lavie, R. Marchioli, and W.S. Harris Omega-3 fatty acids for cardioprotection Mayo Clin Proc 83 2008 324 332
-
(2008)
Mayo Clin Proc
, vol.83
, pp. 324-332
-
-
Lee, J.H.1
O'Keefe, J.H.2
Lavie, C.J.3
Marchioli, R.4
Harris, W.S.5
-
171
-
-
0025897282
-
Gene expression in macrophage-rich human atherosclerotic lesions. 15-lipoxygenase and acetyl low density lipoprotein receptor messenger RNA colocalize with oxidation specific lipid-protein adducts
-
S. Yla-Herttuala, M.E. Rosenfeld, S. Parthasarathy, E. Sigal, T. Sarkioja, and J.L. Witztum Gene expression in macrophage-rich human atherosclerotic lesions. 15-lipoxygenase and acetyl low density lipoprotein receptor messenger RNA colocalize with oxidation specific lipid-protein adducts J Clin Invest 87 1991 1146 1152
-
(1991)
J Clin Invest
, vol.87
, pp. 1146-1152
-
-
Yla-Herttuala, S.1
Rosenfeld, M.E.2
Parthasarathy, S.3
Sigal, E.4
Sarkioja, T.5
Witztum, J.L.6
-
172
-
-
0344145871
-
In vivo action of 15-lipoxygenase in early stages of human atherogenesis
-
H. Kuhn, D. Heydeck, I. Hugou, and C. Gniwotta In vivo action of 15-lipoxygenase in early stages of human atherogenesis J Clin Invest 99 1997 888 893
-
(1997)
J Clin Invest
, vol.99
, pp. 888-893
-
-
Kuhn, H.1
Heydeck, D.2
Hugou, I.3
Gniwotta, C.4
-
173
-
-
74049111313
-
15-Lipoxygenase-2 is expressed in macrophages in human carotid plaques and regulated by hypoxia-inducible factor-1alpha
-
L.M. Hulten, F.J. Olson, H. Aberg, J. Carlsson, L. Karlstrom, and J. Boren 15-Lipoxygenase-2 is expressed in macrophages in human carotid plaques and regulated by hypoxia-inducible factor-1alpha Eur J Clin Invest 40 2010 11 17
-
(2010)
Eur J Clin Invest
, vol.40
, pp. 11-17
-
-
Hulten, L.M.1
Olson, F.J.2
Aberg, H.3
Carlsson, J.4
Karlstrom, L.5
Boren, J.6
-
174
-
-
34247357016
-
The c.-292C>T promoter polymorphism increases reticulocyte-type 15-lipoxygenase-1 activity and could be atheroprotective
-
J. Wittwer, M. Bayer, A. Mosandl, J. Muntwyler, and M. Hersberger The c.-292C>T promoter polymorphism increases reticulocyte-type 15-lipoxygenase-1 activity and could be atheroprotective Clin Chem Lab Med 45 2007 487 492
-
(2007)
Clin Chem Lab Med
, vol.45
, pp. 487-492
-
-
Wittwer, J.1
Bayer, M.2
Mosandl, A.3
Muntwyler, J.4
Hersberger, M.5
-
175
-
-
40949164339
-
A near null variant of 12/15-LOX encoded by a novel SNP in ALOX15 and the risk of coronary artery disease
-
T.L. Assimes, J.W. Knowles, J.R. Priest, A. Basu, A. Borchert, and K.A. Volcik A near null variant of 12/15-LOX encoded by a novel SNP in ALOX15 and the risk of coronary artery disease Atherosclerosis 198 2008 136 144
-
(2008)
Atherosclerosis
, vol.198
, pp. 136-144
-
-
Assimes, T.L.1
Knowles, J.W.2
Priest, J.R.3
Basu, A.4
Borchert, A.5
Volcik, K.A.6
-
176
-
-
77953519631
-
Human lipoxygenase pathway gene variation and association with markers of subclinical atherosclerosis in the diabetes heart study
-
K.P. Burdon, M.E. Rudock, A.B. Lehtinen, C.D. Langefeld, D.W. Bowden, and T.C. Register Human lipoxygenase pathway gene variation and association with markers of subclinical atherosclerosis in the diabetes heart study Mediators Inflamm 2010 2010 170153
-
(2010)
Mediators Inflamm
, vol.2010
, pp. 170153
-
-
Burdon, K.P.1
Rudock, M.E.2
Lehtinen, A.B.3
Langefeld, C.D.4
Bowden, D.W.5
Register, T.C.6
-
177
-
-
0035164723
-
Overexpression of 15-lipoxygenase-1 in PC-3 human prostate cancer cells increases tumorigenesis
-
U.P. Kelavkar, J.B. Nixon, C. Cohen, D. Dillehay, T.E. Eling, and K.F. Badr Overexpression of 15-lipoxygenase-1 in PC-3 human prostate cancer cells increases tumorigenesis Carcinogenesis 22 2001 1765 1773
-
(2001)
Carcinogenesis
, vol.22
, pp. 1765-1773
-
-
Kelavkar, U.P.1
Nixon, J.B.2
Cohen, C.3
Dillehay, D.4
Eling, T.E.5
Badr, K.F.6
-
178
-
-
41149111018
-
15-lipoxygenase-1 prevents vascular endothelial growth factor A- and placental growth factor-induced angiogenic effects in rabbit skeletal muscles via reduction in growth factor mRNA levels, NO bioactivity, and downregulation of VEGF receptor 2 expression
-
H. Viita, J. Markkanen, E. Eriksson, M. Nurminen, K. Kinnunen, and M. Babu 15-lipoxygenase-1 prevents vascular endothelial growth factor A- and placental growth factor-induced angiogenic effects in rabbit skeletal muscles via reduction in growth factor mRNA levels, NO bioactivity, and downregulation of VEGF receptor 2 expression Circ Res 102 2008 177 184
-
(2008)
Circ Res
, vol.102
, pp. 177-184
-
-
Viita, H.1
Markkanen, J.2
Eriksson, E.3
Nurminen, M.4
Kinnunen, K.5
Babu, M.6
-
179
-
-
24344504411
-
Inhibition of carcinogenesis in transgenic mouse models over-expressing 15-lipoxygenase in the vascular wall under the control of murine preproendothelin-1 promoter
-
D. Harats, D. Ben-Shushan, H. Cohen, A. Gonen, I. Barshack, and I. Goldberg Inhibition of carcinogenesis in transgenic mouse models over-expressing 15-lipoxygenase in the vascular wall under the control of murine preproendothelin-1 promoter Cancer Lett 229 2005 127 134
-
(2005)
Cancer Lett
, vol.229
, pp. 127-134
-
-
Harats, D.1
Ben-Shushan, D.2
Cohen, H.3
Gonen, A.4
Barshack, I.5
Goldberg, I.6
-
180
-
-
74549130049
-
Intravitreal adenoviral 15-lipoxygenase-1 gene transfer prevents vascular endothelial growth factor A-induced neovascularization in rabbit eyes
-
H. Viita, K. Kinnunen, E. Eriksson, J. Lahteenvuo, M. Babu, and G. Kalesnykas Intravitreal adenoviral 15-lipoxygenase-1 gene transfer prevents vascular endothelial growth factor A-induced neovascularization in rabbit eyes Hum Gene Ther 20 2009 1679 1686
-
(2009)
Hum Gene Ther
, vol.20
, pp. 1679-1686
-
-
Viita, H.1
Kinnunen, K.2
Eriksson, E.3
Lahteenvuo, J.4
Babu, M.5
Kalesnykas, G.6
-
181
-
-
77949621085
-
Absence of glutathione peroxidase 4 affects tumor angiogenesis through increased 12/15-lipoxygenase activity
-
M. Schneider, M. Wortmann, P.K. Mandal, W. Arpornchayanon, K. Jannasch, and F. Alves Absence of glutathione peroxidase 4 affects tumor angiogenesis through increased 12/15-lipoxygenase activity Neoplasia 12 2010 254 263
-
(2010)
Neoplasia
, vol.12
, pp. 254-263
-
-
Schneider, M.1
Wortmann, M.2
Mandal, P.K.3
Arpornchayanon, W.4
Jannasch, K.5
Alves, F.6
-
182
-
-
77953230908
-
12-Lipoxygenase and the regulation of hypoxia-inducible factor in prostate cancer cells
-
S. Krishnamoorthy, R. Jin, Y. Cai, K.R. Maddipati, D. Nie, and G. Pages 12-Lipoxygenase and the regulation of hypoxia-inducible factor in prostate cancer cells Exp Cell Res 316 2010 1706 1715
-
(2010)
Exp Cell Res
, vol.316
, pp. 1706-1715
-
-
Krishnamoorthy, S.1
Jin, R.2
Cai, Y.3
Maddipati, K.R.4
Nie, D.5
Pages, G.6
-
183
-
-
77950398950
-
15(S)-hydroxyeicosatetraenoic acid-induced angiogenesis requires Src-mediated Egr-1-dependent rapid induction of FGF-2 expression
-
V. Kundumani-Sridharan, J. Niu, D. Wang, D. Van Quyen, Q. Zhang, and N.K. Singh 15(S)-hydroxyeicosatetraenoic acid-induced angiogenesis requires Src-mediated Egr-1-dependent rapid induction of FGF-2 expression Blood 115 2010 2105 2116
-
(2010)
Blood
, vol.115
, pp. 2105-2116
-
-
Kundumani-Sridharan, V.1
Niu, J.2
Wang, D.3
Van Quyen, D.4
Zhang, Q.5
Singh, N.K.6
-
184
-
-
73949160807
-
Endogenous LXA4 circuits are determinants of pathological angiogenesis in response to chronic injury
-
A.J. Leedom, A.B. Sullivan, B. Dong, D. Lau, and K. Gronert Endogenous LXA4 circuits are determinants of pathological angiogenesis in response to chronic injury Am J Pathol 176 2010 74 84
-
(2010)
Am J Pathol
, vol.176
, pp. 74-84
-
-
Leedom, A.J.1
Sullivan, A.B.2
Dong, B.3
Lau, D.4
Gronert, K.5
-
185
-
-
33745797993
-
Eicosanoids and renal vascular function in diseases
-
J.D. Imig Eicosanoids and renal vascular function in diseases Clin Sci (Lond) 111 2006 21 34
-
(2006)
Clin Sci (Lond)
, vol.111
, pp. 21-34
-
-
Imig, J.D.1
-
186
-
-
34249110684
-
Roles of lipid mediators in kidney injury
-
C.M. Hao, and M.D. Breyer Roles of lipid mediators in kidney injury Semin Nephrol 27 2007 338 351
-
(2007)
Semin Nephrol
, vol.27
, pp. 338-351
-
-
Hao, C.M.1
Breyer, M.D.2
-
187
-
-
34249287061
-
Physiologic and pathophysiologic roles of lipid mediators in the kidney
-
C.M. Hao, and M.D. Breyer Physiologic and pathophysiologic roles of lipid mediators in the kidney Kidney Int 71 2007 1105 1115
-
(2007)
Kidney Int
, vol.71
, pp. 1105-1115
-
-
Hao, C.M.1
Breyer, M.D.2
-
188
-
-
0347093588
-
12-Hydroxyeicosatetraenoic acid participates in angiotensin II afferent arteriolar vasoconstriction by activating L-type calcium channels
-
S.S. Yiu, X. Zhao, E.W. Inscho, and J.D. Imig 12-Hydroxyeicosatetraenoic acid participates in angiotensin II afferent arteriolar vasoconstriction by activating L-type calcium channels J Lipid Res 44 2003 2391 2399
-
(2003)
J Lipid Res
, vol.44
, pp. 2391-2399
-
-
Yiu, S.S.1
Zhao, X.2
Inscho, E.W.3
Imig, J.D.4
-
189
-
-
0026699147
-
Renal hemodynamic actions of lipoxins in rats: A comparative physiological study
-
T. Katoh, K. Takahashi, D.K. DeBoer, C.N. Serhan, and K.F. Badr Renal hemodynamic actions of lipoxins in rats: a comparative physiological study Am J Physiol 263 1992 F436 F442
-
(1992)
Am J Physiol
, vol.263
-
-
Katoh, T.1
Takahashi, K.2
Deboer, D.K.3
Serhan, C.N.4
Badr, K.F.5
-
190
-
-
0026693218
-
12-Lipoxygenase products modulate calcium signals in vascular smooth muscle cells
-
F. Saito, M.T. Hori, Y. Ideguchi, M. Berger, M. Golub, and N. Stern 12-Lipoxygenase products modulate calcium signals in vascular smooth muscle cells Hypertension 20 1992 138 143
-
(1992)
Hypertension
, vol.20
, pp. 138-143
-
-
Saito, F.1
Hori, M.T.2
Ideguchi, Y.3
Berger, M.4
Golub, M.5
Stern, N.6
-
191
-
-
67651085473
-
Angiotensin II type 1 receptor expression is increased via 12-lipoxygenase in high glucose-stimulated glomerular cells and type 2 diabetic glomeruli
-
Z.G. Xu, L.N. Miao, Y.C. Cui, Y. Jia, H. Yuan, and M. Wu Angiotensin II type 1 receptor expression is increased via 12-lipoxygenase in high glucose-stimulated glomerular cells and type 2 diabetic glomeruli Nephrol Dial Transplant 24 2009 1744 1752
-
(2009)
Nephrol Dial Transplant
, vol.24
, pp. 1744-1752
-
-
Xu, Z.G.1
Miao, L.N.2
Cui, Y.C.3
Jia, Y.4
Yuan, H.5
Wu, M.6
-
192
-
-
0035210544
-
Interactions of nitric oxide-derived reactive nitrogen species with peroxidases and lipoxygenases
-
M.J. Coffey, B. Coles, and V.B. O'Donnell Interactions of nitric oxide-derived reactive nitrogen species with peroxidases and lipoxygenases Free Radic Res 35 2001 447 464
-
(2001)
Free Radic Res
, vol.35
, pp. 447-464
-
-
Coffey, M.J.1
Coles, B.2
O'Donnell, V.B.3
-
194
-
-
0023473551
-
Specific action of the lipoxygenase pathway in mediating angiotensin II-induced aldosterone synthesis in isolated adrenal glomerulosa cells
-
J.L. Nadler, R. Natarajan, and N. Stern Specific action of the lipoxygenase pathway in mediating angiotensin II-induced aldosterone synthesis in isolated adrenal glomerulosa cells J Clin Invest 80 1987 1763 1769
-
(1987)
J Clin Invest
, vol.80
, pp. 1763-1769
-
-
Nadler, J.L.1
Natarajan, R.2
Stern, N.3
-
195
-
-
72449191387
-
Aldosterone up-regulates 12- and 15-lipoxygenase expression and LDL oxidation in human vascular smooth muscle cells
-
R. Limor, M. Kaplan, O. Sharon, E. Knoll, M. Naidich, and G. Weisinger Aldosterone up-regulates 12- and 15-lipoxygenase expression and LDL oxidation in human vascular smooth muscle cells J Cell Biochem 108 2009 1203 1210
-
(2009)
J Cell Biochem
, vol.108
, pp. 1203-1210
-
-
Limor, R.1
Kaplan, M.2
Sharon, O.3
Knoll, E.4
Naidich, M.5
Weisinger, G.6
-
196
-
-
0035092916
-
Increased levels of 12(S)-HETE in patients with essential hypertension
-
D. Gonzalez-Nunez, J. Claria, F. Rivera, and E. Poch Increased levels of 12(S)-HETE in patients with essential hypertension Hypertension 37 2001 334 338
-
(2001)
Hypertension
, vol.37
, pp. 334-338
-
-
Gonzalez-Nunez, D.1
Claria, J.2
Rivera, F.3
Poch, E.4
-
197
-
-
31544454435
-
A coding polymorphism in the 12-lipoxygenase gene is associated to essential hypertension and urinary 12(S)-HETE
-
L.F. Quintana, B. Guzman, S. Collado, J. Claria, and E. Poch A coding polymorphism in the 12-lipoxygenase gene is associated to essential hypertension and urinary 12(S)-HETE Kidney Int 69 2006 526 530
-
(2006)
Kidney Int
, vol.69
, pp. 526-530
-
-
Quintana, L.F.1
Guzman, B.2
Collado, S.3
Claria, J.4
Poch, E.5
-
198
-
-
0022412370
-
Increase in 12-lipoxygenase activity in platelets of spontaneously hypertensive rats
-
W.C. Chang, and G.W. Su Increase in 12-lipoxygenase activity in platelets of spontaneously hypertensive rats Biochem Biophys Res Commun 127 1985 642 648
-
(1985)
Biochem Biophys Res Commun
, vol.127
, pp. 642-648
-
-
Chang, W.C.1
Su, G.W.2
-
199
-
-
0031002609
-
Elevated 12-lipoxygenase activity in the spontaneously hypertensive rat
-
M. Sasaki, M.T. Hori, T. Hino, M.S. Golub, and M.L. Tuck Elevated 12-lipoxygenase activity in the spontaneously hypertensive rat Am J Hypertens 10 1997 371 378
-
(1997)
Am J Hypertens
, vol.10
, pp. 371-378
-
-
Sasaki, M.1
Hori, M.T.2
Hino, T.3
Golub, M.S.4
Tuck, M.L.5
-
200
-
-
0025643542
-
Inhibition of lipoxygenase pathway reduces blood pressure in renovascular hypertensive rats
-
K. Nozawa, M.L. Tuck, M. Golub, P. Eggena, J.L. Nadler, and N. Stern Inhibition of lipoxygenase pathway reduces blood pressure in renovascular hypertensive rats Am J Physiol 259 1990 H1774 H1780
-
(1990)
Am J Physiol
, vol.259
-
-
Nozawa, K.1
Tuck, M.L.2
Golub, M.3
Eggena, P.4
Nadler, J.L.5
Stern, N.6
-
201
-
-
0034098665
-
Lipoxygenase-dependent mechanisms in hypertension
-
A. DelliPizzi, H. Guan, X. Tong, H. Takizawa, and A. Nasjletti Lipoxygenase-dependent mechanisms in hypertension Clin Exp Hypertens 22 2000 181 192
-
(2000)
Clin Exp Hypertens
, vol.22
, pp. 181-192
-
-
Dellipizzi, A.1
Guan, H.2
Tong, X.3
Takizawa, H.4
Nasjletti, A.5
-
202
-
-
10944228040
-
12-Lipoxygenase metabolism in mouse distal convoluted tubule cells
-
D. Gonzalez-Nunez, M. Sole, R. Natarajan, and E. Poch 12-Lipoxygenase metabolism in mouse distal convoluted tubule cells Kidney Int 67 2005 178 186
-
(2005)
Kidney Int
, vol.67
, pp. 178-186
-
-
Gonzalez-Nunez, D.1
Sole, M.2
Natarajan, R.3
Poch, E.4
-
203
-
-
31544433994
-
Relationship between 12/15-lipoxygenase and COX-2 in mesangial cells: Potential role in diabetic nephropathy
-
Z.G. Xu, S.L. Li, L. Lanting, Y.S. Kim, N. Shanmugam, and M.A. Reddy Relationship between 12/15-lipoxygenase and COX-2 in mesangial cells: potential role in diabetic nephropathy Kidney Int 69 2006 512 519
-
(2006)
Kidney Int
, vol.69
, pp. 512-519
-
-
Xu, Z.G.1
Li, S.L.2
Lanting, L.3
Kim, Y.S.4
Shanmugam, N.5
Reddy, M.A.6
-
204
-
-
0344667756
-
Role of 12-lipoxygenase in the stimulation of p38 mitogen-activated protein kinase and collagen alpha5(IV) in experimental diabetic nephropathy and in glucose-stimulated podocytes
-
S.W. Kang, R. Natarajan, A. Shahed, C.C. Nast, J. LaPage, and P. Mundel Role of 12-lipoxygenase in the stimulation of p38 mitogen-activated protein kinase and collagen alpha5(IV) in experimental diabetic nephropathy and in glucose-stimulated podocytes J Am Soc Nephrol 14 2003 3178 3187
-
(2003)
J Am Soc Nephrol
, vol.14
, pp. 3178-3187
-
-
Kang, S.W.1
Natarajan, R.2
Shahed, A.3
Nast, C.C.4
Lapage, J.5
Mundel, P.6
-
205
-
-
0035071318
-
12-lipoxygenase is increased in glucose-stimulated mesangial cells and in experimental diabetic nephropathy
-
S.W. Kang, S.G. Adler, C.C. Nast, J. LaPage, J.L. Gu, and J.L. Nadler 12-lipoxygenase is increased in glucose-stimulated mesangial cells and in experimental diabetic nephropathy Kidney Int 59 2001 1354 1362
-
(2001)
Kidney Int
, vol.59
, pp. 1354-1362
-
-
Kang, S.W.1
Adler, S.G.2
Nast, C.C.3
Lapage, J.4
Gu, J.L.5
Nadler, J.L.6
-
206
-
-
0029880924
-
A 12-lipoxygenase product, 12-hydroxyeicosatetraenoic acid, is increased in diabetics with incipient and early renal disease
-
I. Antonipillai, J. Nadler, E.J. Vu, S. Bughi, R. Natarajan, and R. Horton A 12-lipoxygenase product, 12-hydroxyeicosatetraenoic acid, is increased in diabetics with incipient and early renal disease J Clin Endocrinol Metab 81 1996 1940 1945
-
(1996)
J Clin Endocrinol Metab
, vol.81
, pp. 1940-1945
-
-
Antonipillai, I.1
Nadler, J.2
Vu, E.J.3
Bughi, S.4
Natarajan, R.5
Horton, R.6
-
207
-
-
0032725609
-
Lipoxygenase products increase monocyte adhesion to human aortic endothelial cells
-
M.K. Patricia, J.A. Kim, C.M. Harper, P.T. Shih, J.A. Berliner, and R. Natarajan Lipoxygenase products increase monocyte adhesion to human aortic endothelial cells Arterioscler Thromb Vasc Biol 19 1999 2615 2622
-
(1999)
Arterioscler Thromb Vasc Biol
, vol.19
, pp. 2615-2622
-
-
Patricia, M.K.1
Kim, J.A.2
Harper, C.M.3
Shih, P.T.4
Berliner, J.A.5
Natarajan, R.6
-
208
-
-
20544459331
-
Novel interactions between TGF-{beta}1 actions and the 12/15-lipoxygenase pathway in mesangial cells
-
Y.S. Kim, Z.G. Xu, M.A. Reddy, S.L. Li, L. Lanting, and K. Sharma Novel interactions between TGF-{beta}1 actions and the 12/15-lipoxygenase pathway in mesangial cells J Am Soc Nephrol 16 2005 352 362
-
(2005)
J Am Soc Nephrol
, vol.16
, pp. 352-362
-
-
Kim, Y.S.1
Xu, Z.G.2
Reddy, M.A.3
Li, S.L.4
Lanting, L.5
Sharma, K.6
-
209
-
-
0142218424
-
Differential behavior of mesangial cells derived from 12/15-lipoxygenase knockout mice relative to control mice
-
Y.S. Kim, M.A. Reddy, L. Lanting, S.G. Adler, and R. Natarajan Differential behavior of mesangial cells derived from 12/15-lipoxygenase knockout mice relative to control mice Kidney Int 64 2003 1702 1714
-
(2003)
Kidney Int
, vol.64
, pp. 1702-1714
-
-
Kim, Y.S.1
Reddy, M.A.2
Lanting, L.3
Adler, S.G.4
Natarajan, R.5
-
210
-
-
0942301316
-
Lipoxins: Endogenous regulators of inflammation
-
B. McMahon, and C. Godson Lipoxins: endogenous regulators of inflammation Am J Physiol Renal Physiol 286 2004 F189 F201
-
(2004)
Am J Physiol Renal Physiol
, vol.286
-
-
McMahon, B.1
Godson, C.2
-
211
-
-
1642422412
-
Lipoxins: Potential anti-inflammatory, proresolution, and antifibrotic mediators in renal disease
-
N.E. Kieran, P. Maderna, and C. Godson Lipoxins: potential anti-inflammatory, proresolution, and antifibrotic mediators in renal disease Kidney Int 65 2004 1145 1154
-
(2004)
Kidney Int
, vol.65
, pp. 1145-1154
-
-
Kieran, N.E.1
Maderna, P.2
Godson, C.3
-
212
-
-
0029670175
-
Lipoxin A4 and B4 inhibit leukotriene-stimulated interactions of human neutrophils and endothelial cells
-
A. Papayianni, C.N. Serhan, and H.R. Brady Lipoxin A4 and B4 inhibit leukotriene-stimulated interactions of human neutrophils and endothelial cells J Immunol 156 1996 2264 2272
-
(1996)
J Immunol
, vol.156
, pp. 2264-2272
-
-
Papayianni, A.1
Serhan, C.N.2
Brady, H.R.3
-
213
-
-
0036831229
-
Lipoxin, leukotriene, and PDGF receptors cross-talk to regulate mesangial cell proliferation
-
B. McMahon, D. Mitchell, R. Shattock, F. Martin, H.R. Brady, and C. Godson Lipoxin, leukotriene, and PDGF receptors cross-talk to regulate mesangial cell proliferation Faseb J 16 2002 1817 1819
-
(2002)
Faseb J
, vol.16
, pp. 1817-1819
-
-
McMahon, B.1
Mitchell, D.2
Shattock, R.3
Martin, F.4
Brady, H.R.5
Godson, C.6
-
214
-
-
0034622672
-
Lipoxin A4 antagonizes the mitogenic effects of leukotriene D4 in human renal mesangial cells. Differential activation of MAP kinases through distinct receptors
-
B. McMahon, C. Stenson, F. McPhillips, A. Fanning, H.R. Brady, and C. Godson Lipoxin A4 antagonizes the mitogenic effects of leukotriene D4 in human renal mesangial cells. Differential activation of MAP kinases through distinct receptors J Biol Chem 275 2000 27566 27575
-
(2000)
J Biol Chem
, vol.275
, pp. 27566-27575
-
-
McMahon, B.1
Stenson, C.2
McPhillips, F.3
Fanning, A.4
Brady, H.R.5
Godson, C.6
-
215
-
-
10744230052
-
Modification of the transcriptomic response to renal ischemia/reperfusion injury by lipoxin analog
-
N.E. Kieran, P.P. Doran, S.B. Connolly, M.C. Greenan, D.F. Higgins, and M. Leonard Modification of the transcriptomic response to renal ischemia/reperfusion injury by lipoxin analog Kidney Int 64 2003 480 492
-
(2003)
Kidney Int
, vol.64
, pp. 480-492
-
-
Kieran, N.E.1
Doran, P.P.2
Connolly, S.B.3
Greenan, M.C.4
Higgins, D.F.5
Leonard, M.6
-
216
-
-
0033539695
-
Transfection of rat kidney with human 15-lipoxygenase suppresses inflammation and preserves function in experimental glomerulonephritis
-
K.A. Munger, A. Montero, M. Fukunaga, S. Uda, T. Yura, and E. Imai Transfection of rat kidney with human 15-lipoxygenase suppresses inflammation and preserves function in experimental glomerulonephritis Proc Natl Acad Sci USA 96 1999 13375 13380
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 13375-13380
-
-
Munger, K.A.1
Montero, A.2
Fukunaga, M.3
Uda, S.4
Yura, T.5
Imai, E.6
-
217
-
-
0036014949
-
15-Epi-16-(para-fluorophenoxy)-lipoxin A(4)-methyl ester, a synthetic analogue of 15-epi-lipoxin A(4), is protective in experimental ischemic acute renal failure
-
M.O. Leonard, K. Hannan, M.J. Burne, D.W. Lappin, P. Doran, and P. Coleman 15-Epi-16-(para-fluorophenoxy)-lipoxin A(4)-methyl ester, a synthetic analogue of 15-epi-lipoxin A(4), is protective in experimental ischemic acute renal failure J Am Soc Nephrol 13 2002 1657 1662
-
(2002)
J Am Soc Nephrol
, vol.13
, pp. 1657-1662
-
-
Leonard, M.O.1
Hannan, K.2
Burne, M.J.3
Lappin, D.W.4
Doran, P.5
Coleman, P.6
-
218
-
-
64849091646
-
Acute changes in dietary omega-3 and omega-6 polyunsaturated fatty acids have a pronounced impact on survival following ischemic renal injury and formation of renoprotective docosahexaenoic acid-derived protectin D1
-
I.R. Hassan, and K. Gronert Acute changes in dietary omega-3 and omega-6 polyunsaturated fatty acids have a pronounced impact on survival following ischemic renal injury and formation of renoprotective docosahexaenoic acid-derived protectin D1 J Immunol 182 2009 3223 3232
-
(2009)
J Immunol
, vol.182
, pp. 3223-3232
-
-
Hassan, I.R.1
Gronert, K.2
-
219
-
-
0032845121
-
Ischemic cell death in brain neurons
-
P. Lipton Ischemic cell death in brain neurons Physiol Rev 79 1999 1431 1568
-
(1999)
Physiol Rev
, vol.79
, pp. 1431-1568
-
-
Lipton, P.1
-
220
-
-
0024353224
-
Effect of cyclooxygenase and lipoxygenase inhibitors on delayed neuronal death in the gerbil hippocampus
-
T. Nakagomi, T. Sasaki, T. Kirino, A. Tamura, M. Noguchi, and I. Saito Effect of cyclooxygenase and lipoxygenase inhibitors on delayed neuronal death in the gerbil hippocampus Stroke 20 1989 925 929
-
(1989)
Stroke
, vol.20
, pp. 925-929
-
-
Nakagomi, T.1
Sasaki, T.2
Kirino, T.3
Tamura, A.4
Noguchi, M.5
Saito, I.6
-
221
-
-
33845442015
-
Baicalein and 12/15-lipoxygenase in the ischemic brain
-
K. van Leyen, H.Y. Kim, S.R. Lee, G. Jin, K. Arai, and E.H. Lo Baicalein and 12/15-lipoxygenase in the ischemic brain Stroke 37 2006 3014 3018
-
(2006)
Stroke
, vol.37
, pp. 3014-3018
-
-
Van Leyen, K.1
Kim, H.Y.2
Lee, S.R.3
Jin, G.4
Arai, K.5
Lo, E.H.6
-
222
-
-
36749068009
-
Baicalein, an antioxidant 12/15-lipoxygenase inhibitor improves clinical rating scores following multiple infarct embolic strokes
-
P.A. Lapchak, P. Maher, D. Schubert, and J.A. Zivin Baicalein, an antioxidant 12/15-lipoxygenase inhibitor improves clinical rating scores following multiple infarct embolic strokes Neuroscience 150 2007 585 591
-
(2007)
Neuroscience
, vol.150
, pp. 585-591
-
-
Lapchak, P.A.1
Maher, P.2
Schubert, D.3
Zivin, J.A.4
-
223
-
-
9344268817
-
Peroxynitrite-induced neuronal apoptosis is mediated by intracellular zinc release and 12-lipoxygenase activation
-
Y. Zhang, H. Wang, J. Li, D.A. Jimenez, E.S. Levitan, and E. Aizenman Peroxynitrite-induced neuronal apoptosis is mediated by intracellular zinc release and 12-lipoxygenase activation J Neurosci 24 2004 10616 10627
-
(2004)
J Neurosci
, vol.24
, pp. 10616-10627
-
-
Zhang, Y.1
Wang, H.2
Li, J.3
Jimenez, D.A.4
Levitan, E.S.5
Aizenman, E.6
-
224
-
-
77953139108
-
Increased nuclear apoptosis-inducing factor after transient focal ischemia: A 12/15-lipoxygenase-dependent organelle damage pathway
-
S. Pallast, K. Arai, A. Pekcec, K. Yigitkanli, Z. Yu, and X. Wang Increased nuclear apoptosis-inducing factor after transient focal ischemia: a 12/15-lipoxygenase-dependent organelle damage pathway J Cereb Blood Flow Metab 30 2010 1157 1167
-
(2010)
J Cereb Blood Flow Metab
, vol.30
, pp. 1157-1167
-
-
Pallast, S.1
Arai, K.2
Pekcec, A.3
Yigitkanli, K.4
Yu, Z.5
Wang, X.6
-
225
-
-
2442621492
-
Role of AIF in caspase-dependent and caspase-independent cell death
-
S.P. Cregan, V.L. Dawson, and R.S. Slack Role of AIF in caspase-dependent and caspase-independent cell death Oncogene 23 2004 2785 2796
-
(2004)
Oncogene
, vol.23
, pp. 2785-2796
-
-
Cregan, S.P.1
Dawson, V.L.2
Slack, R.S.3
-
226
-
-
52449086378
-
Protecting against cerebrovascular injury: Contributions of 12/15-lipoxygenase to edema formation after transient focal ischemia
-
G. Jin, K. Arai, Y. Murata, S. Wang, M.F. Stins, and E.H. Lo Protecting against cerebrovascular injury: contributions of 12/15-lipoxygenase to edema formation after transient focal ischemia Stroke 39 2008 2538 2543
-
(2008)
Stroke
, vol.39
, pp. 2538-2543
-
-
Jin, G.1
Arai, K.2
Murata, Y.3
Wang, S.4
Stins, M.F.5
Lo, E.H.6
-
227
-
-
4344620045
-
Blockade of 12-lipoxygenase expression protects cortical neurons from apoptosis induced by beta-amyloid peptide
-
A. Lebeau, F. Terro, W. Rostene, and D. Pelaprat Blockade of 12-lipoxygenase expression protects cortical neurons from apoptosis induced by beta-amyloid peptide Cell Death Differ 11 2004 875 884
-
(2004)
Cell Death Differ
, vol.11
, pp. 875-884
-
-
Lebeau, A.1
Terro, F.2
Rostene, W.3
Pelaprat, D.4
-
228
-
-
25444475777
-
Elevation of 12/15 lipoxygenase products in AD and mild cognitive impairment
-
Y. Yao, C.M. Clark, J.Q. Trojanowski, V.M. Lee, and D. Pratico Elevation of 12/15 lipoxygenase products in AD and mild cognitive impairment Ann Neurol 58 2005 623 626
-
(2005)
Ann Neurol
, vol.58
, pp. 623-626
-
-
Yao, Y.1
Clark, C.M.2
Trojanowski, J.Q.3
Lee, V.M.4
Pratico, D.5
-
229
-
-
78049423493
-
Amelioration of the Alzheimer's disease phenotype by absence of 12/15-lipoxygenase
-
Yang H, Zhuo JM, Chu J, Chinnici C, Pratico D. Amelioration of the Alzheimer's disease phenotype by absence of 12/15-lipoxygenase. Biol Psychiatry, 2010.
-
(2010)
Biol Psychiatry
-
-
Yang, H.1
Zhuo, J.M.2
Chu, J.3
Chinnici, C.4
Pratico, D.5
-
230
-
-
0030867994
-
A role for 12-lipoxygenase in nerve cell death caused by glutathione depletion
-
DOI 10.1016/S0896-6273(00)80953-8
-
Y. Li, P. Maher, and D. Schubert A role for 12-lipoxygenase in nerve cell death caused by glutathione depletion Neuron 19 1997 453 463 (Pubitemid 27374242)
-
(1997)
Neuron
, vol.19
, Issue.2
, pp. 453-463
-
-
Li, Y.1
Maher, P.2
Schubert, D.3
-
231
-
-
0035664304
-
Glutathione depletion switches nitric oxide neurotrophic effects to cell death in midbrain cultures: Implications for Parkinson's disease
-
S. Canals, M.J. Casarejos, S. de Bernardo, E. Rodriguez-Martin, and M.A. Mena Glutathione depletion switches nitric oxide neurotrophic effects to cell death in midbrain cultures: implications for Parkinson's disease J Neurochem 79 2001 1183 1195
-
(2001)
J Neurochem
, vol.79
, pp. 1183-1195
-
-
Canals, S.1
Casarejos, M.J.2
De Bernardo, S.3
Rodriguez-Martin, E.4
Mena, M.A.5
-
232
-
-
77958464748
-
Discovery of potent and selective inhibitors of human reticulocyte 15-lipoxygenase-1
-
Rai G, Kenyon V, Jadhav A, Schultz L, Armstrong M, Jameson JB, et al. Discovery of potent and selective inhibitors of human reticulocyte 15-lipoxygenase-1. J Med Chem 2010.
-
(2010)
J Med Chem
-
-
Rai, G.1
Kenyon, V.2
Jadhav, A.3
Schultz, L.4
Armstrong, M.5
Jameson, J.B.6
|