12-Lipoxygenase and the regulation of hypoxia-inducible factor in prostate cancer cells

Experimental Cell Research

Volumn 316, Issue 10, 2010, Pages 1706-1715

  Krishnamoorthy, Sriram ^a   Jin, Rongxian ^a   Cai, Yinlong ^a   Maddipati, Krishna Rao ^a,b   Nie, Daotai ^a   Pagès, Gilles ^c   Tucker, Stephanie C ^a   Honn, Kenneth V ^a,b  

^a WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b KARMANOS CANCER INSTITUTE   (United States)

^c UNIVERSITÉ CÔTE D'AZUR   (France)

Author keywords

12 Lipoxygenase; Angiogenesis; Hypoxia; Hypoxia Inducible Factor 1 (HIF 1 ); Prostate cancer

Indexed keywords

ARACHIDONATE 12 LIPOXYGENASE; HYPOXIA INDUCIBLE FACTOR 1ALPHA; MESSENGER RNA; VASCULOTROPIN;

ARTICLE; CANCER CELL; CARCINOGENESIS; CONTROLLED STUDY; DNA BINDING; HUMAN; HUMAN CELL; HYPOXIA; METASTASIS; PRIORITY JOURNAL; PROSTATE CANCER; PROTEIN ANALYSIS; PROTEIN FUNCTION; PROTEIN SECRETION; PROTEIN TARGETING; TRANSCRIPTION INITIATION; TRANSCRIPTION REGULATION; UPREGULATION;

EID: 77953230908     PISSN: 00144827     EISSN: 10902422     Source Type: Journal    
DOI: 10.1016/j.yexcr.2010.03.005     Document Type: Article

References (21)

1. Harris A.L. Hypoxia-a key regulatory factor in tumour growth. Nat. Rev. Cancer 2002, 2:38-47.
2. Hockel M., Vaupel P. Tumor hypoxia: definitions and current clinical, biologic, and molecular aspects. J. Natl. Cancer Inst. 2001, 93:266-276.
3. Semenza G.L. Angiogenesis in ischemic and neoplastic disorders. Annu. Rev. Med. 2003, 54:17-28.
4. Semenza G.L. HIF-1 and tumor progression: pathophysiology and therapeutics. Trends Mol. Med. 2002, 8:S62-S67.
5. Huang L.E., Bunn H.F. Hypoxia-inducible factor and its biomedical relevance. J. Biol. Chem. 2003, 278:19575-19578.
6. Fukuda R., Hirota K., Fan F., Jung Y.D., Ellis L.M., Semenza G.L. Insulin-like growth factor 1 induces hypoxia-inducible factor 1-mediated vascular endothelial growth factor expression, which is dependent on MAP kinase and phosphatidylinositol 3-kinase signaling in colon cancer cells. J. Biol. Chem. 2002, 277:38205-38211.
7. Zhong H., Semenza G.L., Simons J.W., De Marzo A.M. Up-regulation of hypoxia-inducible factor 1alpha is an early event in prostate carcinogenesis. Cancer Detect. Prev. 2004, 28:88-93.
8. Nie D., Krishnamoorthy S., Jin R., Tang K., Chen Y., Qiao Y., Zacharek A., Guo Y., Milanini J., Pages G., Honn K.V. Mechanisms regulating tumor angiogenesis by 12-lipoxygenase in prostate cancer cells. J. Biol. Chem. 2006, 281:18601-18609.
9. Nie D., Hillman G.G., Geddes T., Tang K., Pierson C., Grignon D.J., Honn K.V. Platelet-type 12-lipoxygenase in a human prostate carcinoma stimulates angiogenesis and tumor growth. Cancer Res. 1998, 58:4047-4051.
10. Timar J., Raso E., Dome B., Li L., Grignon D., Nie D., Honn K.V., Hagmann W. Expression, subcellular localization and putative function of platelet-type 12-lipoxygenase in human prostate cancer cell lines of different metastatic potential. Int. J. Cancer 2000, 87:37-43.
11. Nithipatikom K., Isbell M.A., See W.A., Campbell W.B. Elevated 12- and 20-hydroxyeicosatetraenoic acid in urine of patients with prostatic diseases. Cancer Lett. 2006, 233:219-225.
12. McCabe N.P., Selman S.H., Jankun J. Vascular endothelial growth factor production in human prostate cancer cells is stimulated by overexpression of platelet 12-lipoxygenase. Prostate 2006, 66:779-787.
13. Pidgeon G.P., Kandouz M., Meram A., Honn K.V. Mechanisms controlling cell cycle arrest and induction of apoptosis after 12-lipoxygenase inhibition in prostate cancer cells. Cancer Res. 2002, 62:2721-2727.
14. Hudson C.C., Liu M., Chiang G.G., Otterness D.M., Loomis D.C., Kaper F., Giaccia A.J., Abraham R.T. Regulation of hypoxia-inducible factor 1alpha expression and function by the mammalian target of rapamycin. Mol. Cell. Biol. 2002, 22:7004-7014.
15. Huang S.P., Wu M.S., Shun C.T., Wang H.P., Hsieh C.Y., Kuo M.L., Lin J.T. Cyclooxygenase-2 increases hypoxia-inducible factor-1 and vascular endothelial growth factor to promote angiogenesis in gastric carcinoma. J. Biomed. Sci. 2005, 12:229-241.
16. Palayoor S.T., Tofilon P.J., Coleman C.N. Ibuprofen-mediated reduction of hypoxia-inducible factors HIF-1alpha and HIF-2alpha in prostate cancer cells. Clin. Cancer Res. 2003, 9:3150-3157.
17. Minet E., Ernest I., Michel G., Roland I., Remacle J., Raes M., Michiels C. HIF1A gene transcription is dependent on a core promoter sequence encompassing activating and inhibiting sequences located upstream from the transcription initiation site and cis elements located within the 5'UTR. Biochem. Biophys. Res. Commun. 1999, 261:534-540.
18. Iyer N.V., Leung S.W., Semenza G.L. The human hypoxia-inducible factor 1alpha gene: HIF1A structure and evolutionary conservation. Genomics 1998, 52:159-165.
19. Frede S., Stockmann C., Freitag P., Fandrey J. Bacterial lipopolysaccharide induces HIF-1 activation in human monocytes via p44/42 MAPK and NF-kappaB. Biochem. J. 2006, 396:517-527.
20. Kandouz M., Nie D., Pidgeon G.P., Krishnamoorty S., Maddipati K.R., Honn K.V. Platelet-type 12-lipoxygenase activates NF-kB in prostate cancer cells. Prostaglandins Other Lipid Mediat. 2003, 71:189-204.
21. Mottet D., Dumont V., Deccache Y., Demazy C., Ninane N., Raes M., Michiels C. Regulation of hypoxia-inducible factor-1alpha protein level during hypoxic conditions by the phosphatidylinositol 3-kinase/Akt/glycogen synthase kinase 3beta pathway in HepG2 cells. J. Biol. Chem. 2003, 278:31277-31285.