Selective uptake and efflux of cholesteryl linoleate in LDL by macrophages expressing 12/15-lipoxygenase

Biochemical and Biophysical Research Communications

Volumn 338, Issue 1, 2005, Pages 128-135

  Takahashi, Yoshitaka ^a   Zhu, Hong ^b   Xu, Wanpeng ^b   Murakami, Takashi ^b   Iwasaki, Tadao ^c   Hattori, Hiroaki ^c   Yoshimoto, Tanihiro ^b  

^a OKAYAMA PREFECTURAL UNIVERSITY   (Japan)

^b KANAZAWA UNIVERSITY   (Japan)

^c BML   (Japan)

Author keywords

12 15 Lipoxygenase; Arachidonic acid; Cholesteryl linoleate; LDL oxidation; LDL receptor related protein; Macrophages

Indexed keywords

APOLIPOPROTEIN B MESSENGER RNA EDITING ENZYME CATALYTIC POLYPEPTIDE 1; ARACHIDONATE 12 LIPOXYGENASE; ARACHIDONATE 15 LIPOXYGENASE; CHOLESTEROL; IODINE 125; LINOLEIC ACID; LOW DENSITY LIPOPROTEIN CHOLESTEROL; LOW DENSITY LIPOPROTEIN RECEPTOR RELATED PROTEIN; RECEPTOR ANTIBODY;

ANIMAL CELL; ARTICLE; ATHEROGENESIS; CELL CULTURE; CELL LABELING; CHOLESTEROL METABOLISM; CHOLESTEROL TRANSPORT; CONCENTRATION RESPONSE; CONTROLLED STUDY; CULTURE MEDIUM; ENZYME INHIBITION; INCUBATION TIME; MACROPHAGE ACTIVATION; NONHUMAN; OXYGENATION; PERITONEUM MACROPHAGE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION;

ANIMALS; ARACHIDONATE 12-LIPOXYGENASE; ARACHIDONATE 15-LIPOXYGENASE; CELL LINE; CELL MEMBRANE; CHO CELLS; CHOLESTEROL ESTERS; CHOLESTEROL, LDL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CRICETINAE; CRICETULUS; LDL-RECEPTOR RELATED PROTEIN 1; MACROPHAGES, PERITONEAL; MICE; OXYGEN; PROTEIN TRANSPORT;

ANIMALIA;

EID: 27544444125     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2005.07.182     Document Type: Article

References (43)

1. T. Yoshimoto, and Y. Takahashi Arachidonate 12-lipoxygenases Prostaglandins Other Lipid Mediat. 68-69 2002 245 262
2. C.D. Funk Prostaglandins and leukotrienes: advances in eicosanoid biology Science 294 2001 1871 1875
3. A.R. Brash Lipoxygenases: occurrence, functions, catalysis, and acquisition of substrate J. Biol. Chem. 274 1999 23679 23682
4. H. Kuhn, and B.J. Thiele The diversity of the lipoxygenase family. Many sequence data but little information on biological significance FEBS Lett. 449 1999 7 11
5. C.D. Funk The molecular biology of mammalian lipoxygenases and the quest for eicosanoid functions using lipoxygenase-deficient mice Biochim. Biophys. Acta 1304 1996 65 84
6. H. Kuhn, J. Belkner, H. Suzuki, and S. Yamamoto Oxidative modification of human lipoproteins by lipoxygenases of different positional specificities J. Lipid Res. 35 1994 1749 1759
7. J. Belkner, H. Stender, and H. Kuhn The rabbit 15-lipoxygenase preferentially oxygenates LDL cholesterol esters, and this reaction does not require vitamin E J. Biol. Chem. 273 1998 23225 23232
8. M.S. Brown, and J.L. Goldstein Atherosclerosis. Scavenging for receptors Nature 343 1990 508 509
9. D. Steinberg, S. Parthasarathy, T.E. Carew, J.C. Khoo, and J.L. Witztum Beyond cholesterol. Modifications of low-density lipoprotein that increase its atherogenicity N Engl. J. Med. 320 1989 915 924
10. S. Yla-Herttuala, M.E. Rosenfeld, S. Parthasarathy, C.K. Glass, E. Sigal, J.L. Witztum, and D. Steinberg Colocalization of 15-lipoxygenase mRNA and protein with epitopes of oxidized low density lipoprotein in macrophage-rich areas of atherosclerotic lesions Proc. Natl. Acad. Sci. USA 87 1990 6959 6963
11. S. Yla-Herttuala, M.E. Rosenfeld, S. Parthasarathy, E. Sigal, T. Sarkioja, J.L. Witztum, and D. Steinberg Gene expression in macrophage-rich human atherosclerotic lesions. 15-Lipoxygenase and acetyl low density lipoprotein receptor messenger RNA colocalize with oxidation specific lipid-protein adducts J. Clin. Invest. 87 1991 1146 1152
12. G.M. Chisolm, S.L. Hazen, P.L. Fox, and M.K. Cathcart The oxidation of lipoproteins by monocytes-macrophages. Biochemical and biological mechanisms J. Biol. Chem. 274 1999 25959 25962
13. Y. Takahashi, H. Zhu, and T. Yoshimoto Essential roles of lipoxygenases in LDL oxidation and development of atherosclerosis Antioxidant Redox. Signal. 7 2005 423 429
14. L. Zhao, and C.D. Funk 12/15-Lipoxygenase, oxidative modification of LDL and atherogenesis Trends Cardiovasc. Med. 14 2004 191 195
15. T. Sakashita, Y. Takahashi, T. Kinoshita, and T. Yoshimoto Essential involvement of 12-lipoxygenase in regiospecific and stereospecific oxidation of low density lipoprotein by macrophages Eur. J. Biochem. 265 1999 825 831
16. T. Cyrus, J.L. Witztum, D.J. Rader, R. Tangirala, S. Fazio, M.F. Linton, and C.D. Funk Disruption of the 12/15-lipoxygenase gene diminishes atherosclerosis in apo E-deficient mice J. Clin. Invest. 103 1999 1597 1604
17. J. George, A. Afek, A. Shaish, H. Levkovitz, N. Bloom, T. Cyrus, L. Zhao, C.D. Funk, E. Sigal, and D. Harats 12/15-Lipoxygenase gene disruption attenuates atherogenesis in LDL receptor-deficient mice Circulation 104 2001 1646 1650
18. W. Xu, Y. Takahashi, T. Sakashita, T. Iwasaki, H. Hattori, and T. Yoshimoto Low density lipoprotein receptor-related protein is required for macrophage-mediated oxidation of low density lipoprotein by 12/15-lipoxygenase J. Biol. Chem. 276 2001 36454 36459
19. H. Zhu, Y. Takahashi, W. Xu, H. Kawajiri, T. Murakami, M. Yamamoto, S. Iseki, T. Iwasaki, H. Hattori, and T. Yoshimoto Low density lipoprotein receptor-related protein-mediated membrane translocation of 12/15-lipoxygenase is required for oxidation of low density lipoprotein by macrophages J. Biol. Chem. 278 2003 13350 13355
20. S. Swarnakar, J. Beers, D.K. Strickland, S. Azhar, and D.L. Williams The apolipoprotein E-dependent low density lipoprotein cholesteryl ester selective uptake pathway in murine adrenocortical cells involves chondroitin sulfate proteoglycans and an alpha 2-macroglobulin receptor J. Biol. Chem. 276 2001 21121 21128
21. R.C.J. Herz, J.L. Goldstein, V. Esser, and M.S. Brown Low density lipoprotein receptor-related protein mediates uptake of cholesteryl esters derived from apoprotein E-enriched lipoproteins Proc. Natl. Acad. Sci. USA 86 1989 5810 5814
22. S. Mizushima, and S. Nagata pEF-BOS, a powerful mammalian expression vector Nucleic Acids Res. 18 1990 5322
23. D. Zhuang, H. Kawajiri, Y. Takahashi, and T. Yoshimoto Suppression of prostaglandin E(2)-mediated c-fos mRNA induction by interleukin-4 in murine macrophages J. Biochem. (Tokyo) 127 2000 451 456
24. R.E. Morton, and D.B. Zilversmit A plasma inhibitor of triglyceride and cholesteryl ester transfer activities J. Biol. Chem. 256 1981 11992 11995
25. J.E. Groener, R.W. Pelton, and G.M. Kostner Improved estimation of cholesteryl ester transfer/exchange activity in serum or plasma Clin. Chem. 32 1986 283 286
26. E.G. Bligh, and W.J. Dyer A rapid method of total lipid extraction and purification Can. J. Med. Sci. 37 1959 911 917
27. D. Rhainds, M. Brodeur, J. Lapointe, D. Charpentier, L. Falstrault, and L. Brissette The role of human and mouse hepatic scavenger receptor class B type I (SR-BI) in the selective uptake of low-density lipoprotein-cholesteryl esters Biochemistry 42 2003 7527 7538
28. J.T. Gwynne, and D.D. Mahaffee Rat adrenal uptake and metabolism of high density lipoprotein cholesteryl ester J. Biol. Chem. 264 1989 8141 8150
29. 3H]cholesterol efflux to high and low density lipoproteins is dependent on lipoprotein binding to the receptor J. Biol. Chem. 275 2000 29993 30001
30. Y. Ji, B. Jian, N. Wang, Y. Sun, M.L. Moya, M.C. Phillips, G.H. Rothblat, J.B. Swaney, and A.R. Tall Scavenger receptor BI promotes high density lipoprotein-mediated cellular cholesterol efflux J. Biol. Chem. 272 1997 20982 20985
31. S. Acton, A. Rigotti, K.T. Landschulz, S. Xu, H.H. Hobbs, and M. Krieger Identification of scavenger receptor SR-BI as a high density lipoprotein receptor Science 271 1996 518 520
32. R.E. Pitas, T.L. Innerarity, J.N. Weinstein, and R.W. Mahley Acetoacetylated lipoproteins used to distinguish fibroblasts from macrophages in vitro by fluorescence microscopy Arteriosclerosis 1 1981 177 185
33. R.E. Pagano, and R.G. Sleight Defining lipid transport pathways in animal cells Science 229 1985 1051 1057
34. T.P. Hiltunen, and S. Yla-Herttuala Expression of lipoprotein receptors in atherosclerotic lesions Atherosclerosis 137 Suppl. 1998 S81 S88
35. S.K. Moestrup, J. Gliemann, and G. Pallesen Distribution of the alpha 2-macroglobulin receptor/low density lipoprotein receptor-related protein in human tissues Cell Tissue Res. 269 1992 375 382
36. V.A. Folcik, R.A. Nivar-Aristy, L.P. Krajewski, and M.K. Cathcart Lipoxygenase contributes to the oxidation of lipids in human atherosclerotic plaques J. Clin. Invest. 96 1995 504 510
37. H. Kuhn, D. Heydeck, I. Hugou, and C. Gniwotta In vivo action of 15-lipoxygenase in early stages of human atherogenesis J. Clin. Invest. 99 1997 888 893
38. S. Swarnakar, M.E. Reyland, J. Deng, S. Azhar, and D.L. Williams Selective uptake of low density lipoprotein-cholesteryl ester is enhanced by inducible apolipoprotein E expression in cultured mouse adrenocortical cells J. Biol. Chem. 273 1998 12140 12147
39. E.E. Windler, P.T. Kovanen, Y.S. Chao, M.S. Brown, R.J. Havel, and J.L. Goldstein The estradiol-stimulated lipoprotein receptor of rat liver. A binding site that membrane mediates the uptake of rat lipoproteins containing apoproteins B and E J. Biol. Chem. 255 1980 10464 10471
40. T. Hevonoja, M.O. Pentikainen, M.T. Hyvonen, P.T. Kovanen, and M. Ala-Korpela Structure of low density lipoprotein (LDL) particles: basis for understanding molecular changes in modified LDL Biochim. Biophys. Acta 1488 2000 189 210
41. J. Herz, U. Hamann, S. Rogne, O. Myklebost, H. Gausepohl, and K.K. Stanley Surface location and high affinity for calcium of a 500-kDa liver membrane protein closely related to the LDL-receptor suggest a physiological role as lipoprotein receptor EMBO J. 7 1988 4119 4127
42. J. Herz, and D.K. Strickland LRP: a multifunctional scavenger and signaling receptor J. Clin. Invest. 108 2001 779 784
43. G. Vassiliou, and R. McPherson A novel efflux-recapture process underlies the mechanism of high-density lipoprotein cholesteryl ester-selective uptake mediated by the low-density lipoprotein receptor-related protein Arterioscler. Thromb. Vasc. Biol. 24 2004 1669 1675