Lipoxins: Potential anti-inflammatory, proresolution, and antifibrotic mediators in renal disease

Kidney International

Volumn 65, Issue 4, 2004, Pages 1145-1154

  Kieran, Niamh E ^b   Maderna, Paola ^b   Godson, Catherine ^a  

^a UNIVERSITY COLLEGE DUBLIN   (Ireland)

^b NONE

Author keywords

Acute renal failure; Anti inflammatory; Eicosanoids; Glomerulonephritis; Lipoxins

Indexed keywords

CYTOKINE; LIGAND; LIPOXIN; LIPOXIN RECEPTOR; LIPOXYGENASE; RECEPTOR; UNCLASSIFIED DRUG;

ACUTE KIDNEY FAILURE; ANTIFIBROTIC ACTIVITY; ANTIINFLAMMATORY ACTIVITY; DRUG ACTIVITY; DRUG MECHANISM; EXPERIMENTAL MODEL; GLOMERULONEPHRITIS; HOST RESISTANCE; IN VITRO STUDY; IN VIVO STUDY; KIDNEY DISEASE; PRIORITY JOURNAL; REVIEW;

EID: 1642422412     PISSN: 00852538     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1523-1755.2004.00487.x     Document Type: Article

References (84)

1. LAWRENCE T, WILLOUGHBY DA, GILROY DW: Anti-inflammatory lipid mediators and insights into the resolution of inflammation. Nat Rev Immunol 2:787-795, 2002
2. LEVY B, CLISH CB, SCHMIDT B, et al: Lipid mediator class switching during acute inflammation: Signals in resolution. Nat Immunol 2:612-619, 2001
3. MCMAHON B, MITCHELL S, BRADY HR, GODSON C: Lipoxins: Revelations on resolution. Trends Pharmacol Sci 8:391-395, 2001
4. 4 during adhesion of platelets and neutrophils in experimental immune complex glomerulonephritis. Kidney Int 47:1295-1302, 1995
5. PARENTE L, PERRETTI M: Advances in the pathophysiology of constitutive and inducible cycloxygenases: Two enzymes in the spotlight. Biochem Pharmacol 65:153-159, 2003
6. CLARIA J, SERHAN CN: Aspirin triggers previously undescribed bioactive eicosanoids by human endothelial cell-leukocyte interactions. Proc Natl Acad Sci USA 92:9475, 1995
7. CLISH CB, O'BRIEN JA, GRONERT K, et al: Local and systemic delivery of a stable aspirin triggered lipoxin prevents neutrophil recruitment in vivo. Proc Natl Acad Sci USA 96:8247-8252, 1999
8. BREZINSKI ME, SERHAN CN: Selective incorporation of (15S)- hydroxyeicosatetraenoic acid in phosphatidylinositol of human neutrophils: Agonist-induced deacylation and transformation of stored hydroxyeicosanoids. Proc Natl Acad Sci USA 87:6248-6252, 1990
9. ROMANO M, SERHAN CN: Lipoxin generation by permeabilized human platelets. Biochemistry 31:8269-8277, 1992
10. CONRAD DJ, KUHN H, MULKINS M, et al: Specific inflammatory cytokines regulate the expression of human monocyte 15-lipoxygenase. Proc Natl Acad Sci USA 89:217-221, 1992
11. BRINCKMANN R, TOPP MS, ZALAN I, et al: Regulation of 15-lipoxygenase expression in lung epithelial cells by interleukin-4. Biochem J 318:305-312, 1996
12. STANKOVA J, ROLA-PLESZCZYNSKI M, DUBOIS CM: Granulocyte-macrophage colony-stimulating factor increases 5-lipoxygenase gene transcription and protein expression in human neutrophils. Blood 85:3719-3726, 1995
13. 4 synthase pathway in mouse mast cells. J Biol Chem 270:22653-22656, 1995
14. FIORE S, SERHAN CN: Formation of lipoxins and leukotrienes during receptor-mediated interactions of human platelets and recombinant human granulocyte/macrophage colony-stimulating factor-primed neutrophils. J Exp Med 172:1451-1457, 1990
15. 4 analogs with increased biologic activity. FASEB J 12:487-494, 1998
16. 4 stable analogs that block transmigration and adhesion of human neutrophils. Biochemistry 34:14609-14615, 1995
17. 4 stable analogues are potent inhibitors of acute inflammation: Evidence for anti-inflammatory receptors. J Exp Med 185:1693-1704, 1997
18. 4 receptor. J Biol Chem 272:6972-6978, 1997
19. 4 inhibit human neutrophil migration: Comparisons between synthetic 15 epimers in chemotaxis and transmigration with microvessel endothelial cells and epithelial cells. J Immunol 170:2688-2694, 2003
20. SERHAN CN, CLISH CB, BRANNON J, et al: Novel functional sets of lipid-derived mediators with anti-inflammatory actions generated from omega-3 fatty acids via cyclooxygenase 2-nonsteroidal anti-inflammatory drugs and transcellular processing. J Exp Med 192:1197-1204, 2000
21. SERHAN CN, HONG S, GRONERT K, et al: Resolvins: A family of bioactive products of omega-3 fatty acid transformation circuits initiated by aspirin treatment that counter proinflammation signals. J Exp Med 196:1025-1037, 2002
22. HE R, SANG H, YE RD: Serum amyloid A induces IL-8 secretion through a G protein-coupled receptor, FPRL1/LXA4R. Blood 101:1572-1581, 2003
23. 4 receptor. Nat Med 8:1296-1302, 2002
24. GAVINS FN, YONA S, KAMAL AM, et al: Leukocyte anti-adhesive actions of annexin 1: ALXR and FPR related anti-inflammatory mechanisms. Blood 101:4140-4147, 2003
25. HANNON R, CROXTALL JD, GETTING SJ, et al: Aberrant inflammation and resistance to glucocorticoids in annexin 1-/-mouse. FASEB J 17:253-255, 2003
26. KATOH T, TAKAHASHI K, DEBOER DK, et al: Renal hemodynamic actions of lipoxins in rats: A comparative physiological study. Am J Physiol 263:F436-F442, 1992
27. 4 in rat glomerular mesangial cells: Evidence for competition at a common receptor. Proc Natl Acad Sci USA 86:3438-3442, 1989
28. 4 and related compounds in smooth muscle preparations and on the microcirculation in vivo. Adv Exp Med Biol 229:107-130, 1988
29. 4 on airway responses in asthmatic subjects. Am Rev Respir Dis 145:1281-1284, 1992
30. 4. Nat Med 8:1018-1023, 2002
31. 4 inhibits cholinergic neurotransmission through nitric oxide generation in the rabbit trachea. Eur J Pharmacol 287:233-238, 1995
32. 4. FEBS Lett 263:117-120, 1990
33. 4 in human renal mesangial cells. J Biol Chem 275:27566-27575, 2000
34. 4 and N-formyl-L-methionyl-L-leucyl-L-phenylalanine. Clin Sci (Lond) 77:195-203, 1989
35. 4 receptor interaction. Biochemistry 34:16678-16686, 1995
36. FILEP JG, ZOUKI C, PETASIS NA, et al: Anti-inflammatory actions of lipoxin A(4) stable analogs are demonstrable in human whole blood: Modulation of leukocyte adhesion molecules and inhibition of neutrophil-endothelial interactions. Blood 94:4132-4142, 1999
37. 4 modulates transmigration of human neutrophils across intestinal epithelial monolayers. J Clin Invest 92:75-82, 1993
38. 4 block allergen-induced eosinophil trafficking. J Immunol 164:2267-2271, 2000
39. 4 inhibit leukotriene-stimulated interactions of human neutrophils and endothelial cells. J Immunol 156:2264-2272, 1996
40. BRADY HR, PERSSON U, BALLERMANN BJ, et al: Leukotrienes stimulate neutrophil adhesion to mesangial cells: modulation with lipoxins. Am J Physiol 259:F809-F815, 1990
41. 4 receptor transgenic mice reveal novel protective roles for lipoxins and aspirin-triggered lipoxins in reperfusion. J Clin Invest 104:309-316, 1999
42. LEONARD MO, HANNAN K, BURNE MJ, et al: 15-Epi-16-(parafluorophenoxy)- lipoxin A(4)-methyl ester, a synthetic analogue of 15-epi-lipoxin A(4), is protective in experimental ischemic acute renal failure. J Am Soc Nephrol 13:1657-1662, 2002
43. KIERAN NE, DORAN PP, CONNOLLY SB, et al: Modification of the transcriptomic response to renal ischemia reperfusion injury by lipoxin analogue. Kidney Int 64:480-492, 2003
44. 4 inhibits IL-1 beta-induced IL-6, IL-8, and matrix metalloproteinase-3 production in human synovial fibroblasts and enhances synthesis of tissue inhibitors of metalloproteinases. J Immunol 164:2660-2666, 2000
45. 4 receptor that is regulated by interleukin (IL)-13 and Interferon gamma and inhibits tumor necrosis factor alpha-induced IL-8 release. J Exp Med 187:1285-1294, 1998
46. 4 antagonize TNF-alpha-stimulated neutrophil-enterocyte interactions in vitro and attenuate TNF-alpha-induced chemokine release and colonocyte apoptosis in human intestinal mucosa ex vivo. J Immunol 167:2772-2780, 2001
47. 4 analogs. J Clin Invest 101:1860-1869, 1998
48. 4 inhibit tumor necrosis factor 1 alpha-initiated neutrophil responses and trafficking: Regulators of a cytokine-chemokine axis. J Exp Med 189:1923-1930, 1999
49. ALIBERTI J, HIENY S, REIS E SOUSA C, et al: Lipoxin-mediated inhibition of IL-12 production by DCs: A mechanism for regulation of microbial immunity. Nat Immunol 3:76-82, 2002
50. 4 is an endogenous regulator of IL-12 production and immunopathology in Toxoplasma gondii infection. J Exp Med 196:1253-1262, 2002
51. 4 analogs block extracellular signal-regulated kinase-dependent TNF-alpha secretion from human T cells. J Immunol 170:6266-6272, 2003
52. CANNY G, LEVY O, FURUTA GT, et al: Lipid mediator-induced expression of bactericidal/permeability-increasing protein (BPI) in human mucosal epithelia. Proc Natl Acad Sci USA 99:3902-3907, 2002
53. GODSON C, MITCHELL S, HARVEY K, et al: Cutting edge: Lipoxins rapidly stimulate nonphlogistic phagocytosis of apoptotic neutrophils by monocyte-derived macrophages. J Immunol 164:1663-1667, 2000
54. MITCHELL S, THOMAS G, HARVEY K, et al: Lipoxins, aspirin-triggered epi-lipoxins, lipoxin stable analogues, and the resolution of inflammation: Stimulation of macrophage phagocytosis of apoptotic neutrophils in vivo. J Am Soc Nephrol 13:2497-2507, 2002
55. MADERNA P, COTTELL DC, BERLASCONI G, et al: Lipoxins induce actin reorganization in monocytes and macrophages but not in neutrophils: Differential involvement of rho GTPases. Am J Pathol 160:2275-2283, 2002
56. MCMAHON B, MITCHELL D, SHATTOCK R, et al: Lipoxin, leukotriene, and PDGF receptors cross-talk to regulate mesangial cell proliferation. FASEB J 16:1817-1819, 2002
57. 4. J Pharmacol Exp Ther 300:385-392, 2002
58. 4 stable analog displays a unique topical anti-inflammatory profile. J Immunol 169:7063-7070, 2002
59. CLERMONT G, ACKER CG, ANGUS DC, et al: Renal failure in the ICU: Comparison of the impact of acute renal failure and end-stage renal disease on ICU outcomes. Kidney Int 62:986-996, 2002
60. MEHTA RL, MCDONALD B, GABBAI FB, et al: Collaborative Group for Treatment of ARF in the ICU. A randomized clinical trial of continuous versus intermittent dialysis for acute renal failure. Kidney Int 60:1154-1163, 2001
61. BRADY HR, BRENNER BM, CLARKSON MR, LIEBERTHAL W: Acute renal failure, in The Kidney (6th ed), edited by Brenner BM, Rector FC, Philadelphia, WB Saunders, 2000, pp 1201-1262
62. MAYADAS TN, MENDRICK DL, BRADY HR, et al: Acute passive anti-glomerular basement membrane nephritis in P-selectin-deficient mice. Kidney Int 49:1342-1349, 1996
63. MONTERO A, FUKUNAGA M, UDA S, et al: Transfection of rat kidney with human 15-lipoxygenase suppresses inflammation and preserves function in experimental glomerulonephritis. Proc Natl Acad Sci USA 96:13375-13380, 1999
64. 4 in the bronchoalveolar lavage fluids obtained from patients with selected pulmonary diseases. Am Rev Respir Dis 141:1453-1458, 1990
65. BONNANS C, VACHIER I, CHAVIS C, et al: Lipoxins are potential endogenous antiinflammatory mediators in asthma. Am J Respir Crit Care Med 165:1531-1535, 2002
66. SANAK M, LEVY BD, CLISH CB, et al: Aspirin-tolerant asthmatics generate more lipoxins than aspirin-intolerant asthmatics. Eur Respir J 16:44-49, 2000
67. 4. Nat Med 8:1018-1023, 2002
68. 4 on airway responses in asthmatic subjects. Am Rev Respir Dis 145:1281-1284, 1992
69. 4 and related compounds in smooth muscle preparations and on the microcirculation in vivo. Adv Exp Med Biol 229:107-130 1988
70. 4 stimulates a cytosolic Ca2+ increase in human bronchial epithelium. J Biol Chem 278:10879-10884, 2003
71. 4 stable analogues. J Clin Invest 101:819-826, 1998
72. 4 stable analog displays a unique topical anti-inflammatory profile. J Immunol 169:7063-7070, 2002
73. 4 analogues inhibit leukocyte recruitment to Porphyromonas gingivalis: A role for cyclooxygenase-2 and lipoxins in periodontal disease. Biochemistry 25:4761-4768, 2000
74. SOUZA MH, DE LIMA OM JR, ZAMUNER SR, et al: Gastritis increases resistance to aspirin-induced mucosal injury via COX-2-mediated lipoxin synthesis. Am J Physiol Gastrointest Liver Physiol 285:G54-G61, 2003
75. 4 receptor homologue gene. J Immunol 169:3363-3369, 2002
76. BRINK C, DAHLEN SE, DRAZEN J, et al: International Union of Pharmacology XXXVII. Nomenclature for Leukotriene and Lipoxin Receptors. Pharmacol Rev 5:195-227, 2003
77. 4'S anti-inflammatory actions on intestinal epithelium. Am J Physiol Cell 284:C888-C896, 2003
78. 4: A new class of ligand for the Ah receptor. Biochemistry 38:7594-7600, 1999
79. LEVY BD, PETASIS NA, SERHAN CN: Polyisoprenyl phosphates in intracellular signalling. Nature 389:985-990, 1997
80. 4. FASEB J 13:903-911, 1999
81. 4 analogs attenuate induction of intestinal epithelial proinflammatory gene expression and reduce the severity of dextran sodium sulfate-induced colitis. J Immunol 168:5260-5267, 2002
82. 4 inhibit peroxynitrite formation, NF-kappa B and AP-1 activation, and IL-8 gene expression in human leukocytes. Proc Natl Acad Sci USA 9:13266-13271, 2002
83. 4 up-regulate transcriptional corepressor NAB1 in human neutrophils. FASEB J 15:2736-2738, 2001
84. SHANKLAND SJ, JOHNSON RJ: TGF-beta in glomerular disease. Miner Electrolyte Metab 24:168-173, 1998