Protecting against cerebrovascular injury: Contributions of 12/15-lipoxygenase to edema formation after transient focal ischemia

Stroke

Volumn 39, Issue 9, 2008, Pages 2538-2543

  Jin, Guang ^a   Arai, Ken ^a   Murata, Yoshihiro ^a   Wang, Sophia ^a   Stins, Monique F ^b   Lo, Eng H ^a   Van Leyen, Klaus ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Baicalein; Blood brain barrier; Edema; Endothelial cell; Lipoxygenase

Indexed keywords

ARACHIDONATE 12 LIPOXYGENASE; ARACHIDONATE 15 LIPOXYGENASE; BAICALEIN; CLAUDIN 5; HYDROGEN PEROXIDE; IMMUNOGLOBULIN G; 12 15 LIPOXYGENASE; 12-15-LIPOXYGENASE; CLDN5 PROTEIN, HUMAN; ENZYME INHIBITOR; FLAVANONE DERIVATIVE; MEMBRANE PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD BRAIN BARRIER; BRAIN BLOOD VESSEL; BRAIN CELL; BRAIN EDEMA; BRAIN HYPOXIA; BRAIN INFARCTION; BRAIN ISCHEMIA; CELL CULTURE; CEREBROVASCULAR ACCIDENT; CONTROLLED STUDY; DRY WEIGHT; ENDOTHELIUM CELL; HEMISPHERE; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IN VIVO STUDY; MALE; MIDDLE CEREBRAL ARTERY OCCLUSION; MOUSE; NERVE CELL; NEUROPROTECTION; NONHUMAN; OXIDATIVE STRESS; PARENCHYMA; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; WILD TYPE; ANIMAL; C57BL MOUSE; CELL PROTECTION; DRUG EFFECT; ENZYMOLOGY; GENETICS; METABOLISM; MOUSE MUTANT; PATHOPHYSIOLOGY; PHYSIOLOGY; TIGHT JUNCTION; TRANSIENT ISCHEMIC ATTACK;

ANIMALS; ARACHIDONATE 12-LIPOXYGENASE; ARACHIDONATE 15-LIPOXYGENASE; BLOOD-BRAIN BARRIER; BRAIN EDEMA; BRAIN INFARCTION; BRAIN ISCHEMIA; CELLS, CULTURED; CYTOPROTECTION; ENDOTHELIAL CELLS; ENZYME INHIBITORS; FLAVANONES; HUMANS; HYDROGEN PEROXIDE; IMMUNOGLOBULIN G; ISCHEMIC ATTACK, TRANSIENT; MEMBRANE PROTEINS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; OXIDATIVE STRESS; TIGHT JUNCTIONS;

EID: 52449086378     PISSN: 00392499     EISSN: None     Source Type: Journal    
DOI: 10.1161/STROKEAHA.108.514927     Document Type: Article

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