12-lipoxygenase products reduce insulin secretion and β-cell viability in human islets

Journal of Clinical Endocrinology and Metabolism

Volumn 95, Issue 2, 2010, Pages 887-893

  Ma, K ^a   Nunemaker, C S ^b   Wu, R ^b   Chakrabarti, S K ^a   Taylor Fishwick, D A ^a   Nadler, J L ^a  

^a EASTERN VIRGINIA MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF VIRGINIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

12 HYDROXYICOSATETRAENOIC ACID; 15 HYDROXYICOSATETRAENOIC ACID; 3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; ACTIN; ARACHIDONATE 12 LIPOXYGENASE; ARACHIDONIC ACID; CYTOKINE; HYDROXYICOSATETRAENOIC ACID; INSULIN; LINOLEIC ACID; LISOFYLLINE; MITOGEN ACTIVATED PROTEIN KINASE P38; SMALL INTERFERING RNA; STRESS ACTIVATED PROTEIN KINASE; STRESS ACTIVATED PROTEIN KINASE 1;

ARTICLE; CELL DEATH; CELL VIABILITY; CONTROLLED STUDY; DIABETES MELLITUS; ENZYME ACTIVITY; ENZYME MECHANISM; ENZYME PHOSPHORYLATION; FATTY ACID OXIDATION; HUMAN; HUMAN CELL; INFLAMMATION; INSULIN RELEASE; MITOCHONDRION; MOUSE; NONHUMAN; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; RODENT; UPREGULATION;

MUS; RODENTIA;

EID: 76149125754     PISSN: 0021972X     EISSN: 0021972X     Source Type: Journal    
DOI: 10.1210/jc.2009-1102     Document Type: Article

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