Lipoxins, aspirin-triggered epi-lipoxins, lipoxin stable analogues, and the resolution of inflammation: Stimulation of macrophage phagocytosis of apoptotic neutrophils in vivo

Journal of the American Society of Nephrology

Volumn 13, Issue 10, 2002, Pages 2497-2507

  Mitchell, Siobhan ^a   Thomas, Graham ^a   Harvey, Killeen ^a   Cottell, David ^a   Reville, Keira ^a   Berlasconi, Giovanni ^a   Petasis, Nicos A ^a   Erwig, Lars ^a   Rees, Andrew J ^a   Savill, John ^a   Brady, Hugh R ^a   Godson, Catherine ^a  

^a UNIVERSITY COLLEGE DUBLIN   (Ireland)

Author keywords

[No Author keywords available]

Indexed keywords

15 METHYLLIPOXIN A4; ACETYLSALICYLIC ACID; BETA 1,3 GLUCAN; LEUCYLGLUTAMYLSERYLISOLEUCYLPHENYLALANYLARGINYLSERYLLEUCYLLEUCYLPHENYLALANY LARGINYLVALYLMETHIONINE; LIPOXIN; LIPOXIN A; LIPOXIN B; LIPOXIN DERIVATIVE; METHIONYLTYROSYLPHENYLALANYLISOLEUCYLASPARAGINYLISOLEUCYLTHREONYLLEUCINE; PEPTIDE DERIVATIVE; PHOSPHATIDYLSERINE; PROTEIN KINASE C; THIOGLYCOLIC ACID; TRANSFORMING GROWTH FACTOR BETA1; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CELL INTERACTION; CELL STIMULATION; CONTROLLED STUDY; ENZYME INHIBITION; HUMAN; HUMAN CELL; IN VIVO STUDY; INFLAMMATION; MACROPHAGE; MALE; MOLECULAR RECOGNITION; NEUTROPHIL; NONHUMAN; PERITONITIS; PHAGOCYTOSIS; PRIORITY JOURNAL; PROTEIN SECRETION; PROTEIN SYNTHESIS; RAT;

EID: 18544378668     PISSN: 10466673     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.ASN.0000032417.73640.72     Document Type: Article

References (52)

1. Savill J, Fadok VA: Corpse clearance defines the meaning of cell death. Nature 407: 784-787, 2000
2. Johnson R, Klebanoff SJ, Couser WG: Cellular mediators of immune injury: Neutrophils, In: Immunologic Renal Diseases, edited by Neilson EG, Couser WG: Philadelphia, Lippincott-Raven, 1997, pp 547-560
3. Taylor PR, Carugati A, Fadok VA, Cook HT, Andrews M, Carroll MC, Savill JS, Henson PM, Botto M, Walport MJ: A hierarchical role for classical pathway complement proteins in the clearance of apoptotic cells in vivo. J Exp Med 192: 3359-3366, 2000
4. McMahon B, Mitchell S, Brady HR, Godson C: Lipoxins: Revelations on resolution. TiPS 22: 391-395, 2001
5. Serhan CN, Hamberg M, Samuellson B: Lipoxins: Novel series of biologically active compounds formed from arachidonic acid in human leukocytes. Proc Natl Acad Sci USA 81: 5335-4339, 1984
6. 4 during adhesion of platelets and neutrophils in experimental immune complex glomerulonephritis. Kidney Int 47: 1295-1302, 1994
7. 4 inhibit leukotriene-stimulated interactions of human neutrophils and endothelial cells. J Immunol 156: 2264-72, 1996
8. Mayadas TN, Mendrick DL, Brady HR, Tang T, Papayianni A, Assmann K: Acute passive anti-glomerular basement membrane nephritis in P-selectin deficient mice. Kidney Int 49: 1342-1349, 1996
9. Munger KA, Montero A, Fukunaga M, Uda S, Yura T, Imai E, Kaneda Y, Valdivielso JM, Badr KF: Transfection of rat kidney with human 15-lipoxygenase suppresses inflammation and preserves function in experimental glomerulonephritis. Proc Natl Acad Sci USA 96: 13375-13380, 1999
10. Katoh T, Lakkis FG, Makita N, Badr KF: Co-regulated expression of glomerular 12/15-lipoxygenase and interleukin-4 mRNAs in rat nephrotoxic nephritis. Kidney Int 46: 341-349, 1994
11. 4 inhibit tumor necrosis factor alpha-initiated neutrophil responses and trafficking: regulators of a cytokine-chemokine axis. J Exp Med 189: 1923-1929, 1999
12. 4 receptor that is regulated by interleukin[IL]-13 and interferon-γ and inhibits tumor necrosis factor α-induced IL-8 release. J Exp Med 187: 1285-1294, 1998
13. 4 inhibits IL-1 β-induced IL-6, IL-8 and matrix metalloproteinase-3 production in human synovial fibroblasts and enhances synthesis of tissue inhibitors of metalloproteinases. J Immunol 164:2660-2666, 2000
14. 4 block allergen induced eosinophil trafficking. J Immunol 164: 2267-2271, 2000
15. 4 in human renal mesangial cells. J Biol Chem 275: 27566-27575, 2000
16. Godson C, Mitchell S, Harvey K, Petasis NA, Hogg N, Brady HR: Cutting edge: Lipoxins rapidly stimulate nonphlogistic phagocytosis of apoptotic neutrophils by monocyte-derived macrophages. J Immunol 164: 1663-1667, 2000
17. 4 analoges with increased biological activity. FASEB J 12: 487-494, 1998
18. Claria J, Serhan CN: Aspirin triggers previously undescribed bioactive eicosanoids by human endothelial cell-leukocyte interactions. Proc Natl Acad Sci USA 92: 9475-9479, 1995
19. 4 receptors by aspirin-triggered lipoxins and select peptides evokes ligand-specific responses in inflammation. J Exp Med 191: 1197-1207, 2000
20. Clish CB, O'Brien JA, Gronert K, Stahl GL, Petasis NA, Serhan CN: Local and systemic delivery of a stable-aspirin-triggered lipoxin prevents neutrophil recruitment in vivo. Proc Natl Acad Sci USA 96: 8247-8252, 1999
21. Serhan CN, Maddox JF, Petasis NA, Akritopoulou-Zanzel, Papayianni A, Brady HR, Colgan SP, Madara JL: Design of Lipoxin A4 stable analogues that block transmigration and adhesion of human neutrophils. Biochemistry 34: 14609-14615, 1995
22. Savill JS, Hogg N, Ren Y, Haslett C: Thrombospondin cooperates with CD36 and the vitronectin receptor in macrophage recognition of neutrophils undergoing apoptosis. J Clin Invest 90:1513-15, 1992
23. Fadok VA, Bratton DL, Rose DM, Pearson A, Ezekwitz RAB, Henson PM: A receptor for phosphatidylserine specific clearance of apoptotic cells. Nature 405: 85-90, 2000
24. Rossi AG, McCutcheon J, Roy N, Chilvers ER, Haslett C, Dransfield I: Regulation of macrophage phagocytosis of apoptotic cells by cAMP. J Immunol 160: 3562-3568, 1998
25. v: β3]. J Immunol 161: 6250-6257, 1998
26. Lake FR, Nobel PW, Henson PM, Richies DW: Functional switching of macrophage responses to tumor necrosis factor-α (TNF-α) by IFNs: Implications for the pleiotropic activities of TNF-α. J Clin Invest 93: 1661-16, 1994
27. Klein C, Paul JI, Sauve K, Schmidt MM, Arcangeli L, Ransom J, Trueheart J, Manfredi JP, Broach JR, Murphy AJ: Identification of surrogate agonists for the human FPRL-1 receptor by autocrine selection in yeast. Nature Biotechnol 16: 1334-1337, 1998
28. 2, and PAF. J Clin Invest 101: 890-898, 1997
29. Fadok V, deCathelineau A, Daleke DL, Henson PM, Bratton DL: Loss of phospholipid asymmetry and surface exposure of phosphatidylserine is required for phagocytosis of apoptotic cells by macrophages and fibroblasts. J Biol Chem 276: 1071-1077, 2001
30. Erwig LP, Kluth DC, Walshe GM, Rees AJ: Initial cytokine exposure determines function of macrophages and renders them unresponsive to other cytokines. J Immunol 161: 1983-1988, 1998
31. Savill J, Smith J, Sarraf C, Ren Y, Abbott F, Rees A: Glomerular mesangial cells and inflammatory macrophages ingest neutrophils undergoing apoptosis. Kidney Int 42: 924-936, 1992
32. Botto M, Dell'Agnola C, Bygrave AE, Thompson EA, Cook HT, Petry F, Loos M, Pandolfi PP, Walport MJ: Homozygous Clq deficiency causes glomerulonephritis associated with multiple apoptotic bodies. Nature Genetics 19: 56-59, 1998
33. 4 and other lipoxygenase-derived eicosanoids on tissue factor expression. Am J Physiol Cell 279: 945-953, 2000
34. Kwiatkowska K, Sobota A: Signalling pathways in phagocytosis. Bioessays 21: 422-431, 1999
35. Larsen EC, DiGennaro J, Saito N, Mehta S, Loegering DJ, Mazurkiewicz JE, Lennartz MR: Differential requirement for classic and novel PKC isoforms in respiratory burst and phagocytosis in RAW 264.7 cells. J Immunol 165: 2809-2817, 2000
36. 4. J Immunol 157: 2149-2154, 1996
37. Maderna P Cottell, D. Berlasconi G Petasis, NA Brady HR, Godson C: Lipoxins induce actin rearrangement in monocytes and macrophages but not in neutrophils. Am J Pathol 160: 2275-2283, 2002
38. Ren Y, Silverstein RL, Allen J, Savill JS: CD36 gene transfer confers capacity for phagocytosis of cells undergoing apoptosis. J Exp Med 181: 1857-1862, 1995
39. Hall A, Aderem A: Mechanisms of phagocytosis. Curr Opin Immunol 8: 36-40, 1996
40. Lang P, Gerbert F, Delespine-Carmagnat M, Stancou R, Pouchelet M, Bertoglio J: Protein kinase A phosphorylation of Rho A mediates the morphological and functional effects of cAMP in cytotoxic lymphocytes. EMBO J 15: 510-519, 1996
41. Frasch SC, Henson PM, Kailey JM, Janes DM, Fadox VA, Bratton DL: Regulation of phospholipid scramblase activity during apoptosis and cell activation by protein kinase C delta. J Biol Chem 275: 23065-23073, 2000
42. McDonald PP, Fadok VA, Bratton D, Henson PM: Transcriptional and translational regulation of inflammatory mediated production by endogenous TGF-β in macrophages that have ingested apoptotic cells. J Immunol 163: 6164-6171, 1999
43. Cocco RE, Ucker DS: Distinct modes of macrophages recognition for apoptotic and necrotic cells are not specified exclusively by phosphatidylserine exposure. Mol Biol Cell 12: 919-930, 2001
44. Giles KM, Ross K, Rossi AG, Hotchin NA, Haslett C, Dransfield I: Glucocorticoid augmentation of macrophage capacity for phagocytosis of apoptotic cells is associated with reduced p130Cas expression, loss of paxillin/pyk2 phosphorylation, and high levels of active Rac. J Immunol 167: 976-986, 2001
45. Scott R, McMahon EJ, Pop SM, Reap EA, Caricchio R, Cohen PL, Shelton Earp H, Matsushima GK: Phagocytosis and clearance of apoptotic cells is mediated by MER. Nature 411: 207-210, 2001
46. 4 receptor. J Exp Med 180: 253-260, 1994
47. 4 with human neutrophils. J Biol Chem 267: 16168-16179, 1992
48. Su SB, Gong W, Gao JL, Shen W, Dunlop NM, Murphy PM, Oppenheim JJ, Wang JM: A seven transmembrane, G-protein coupled receptor, FPRL1 mediates the chemotactic activity of serum amyloid A for human phagocytic cells. J Exp Med 189: 395-402, 1999
49. 106-126 is a chemotactic agonist for the G protein-coupled receptor formyl peptide receptor-like 1. J Immunol 166: 1448-1451, 2001
50. Le Y, Gong W, Tiffany HL, Tumanov A, Nedospasov S, Shen W, Dunlop NM, Gao JL, Murphy PM, Oppenheim JJ, Wang JM: Amyloid (beta)42 activates a G-protein-coupled chemoattractant receptor, FPR-like-1. J Neurosci 2, RC123, 2001
51. 4R and is an agonist for the orphan monocyte-expressed chemoattractant receptor FPRL2. J Biol Chem 276: 21585-21593, 2001
52. Huynh, M-L, Fadok, VA Henson, P Phosphatidylserine-dependent ingestion of apoptotic cells promotes TGF-β1 secretion and the resolution of inflammation. J Clin Invest 109: 41-50, 2002