Novel human lipoxygenase inhibitors discovered using virtual screening with homology models

Journal of Medicinal Chemistry

Volumn 49, Issue 4, 2006, Pages 1356-1363

  Kenyon, Victor ^b   Chorny, Ilya ^a   Carvajal, Wendy J ^b   Holman, Theodore R ^b   Jacobson, Matthew P ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARACHIDONATE 12 LIPOXYGENASE; ARACHIDONATE 15 LIPOXYGENASE; LIPOXYGENASE INHIBITOR;

ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; DRUG PROTEIN BINDING; DRUG SCREENING; DRUG SELECTIVITY; ENZYME SPECIFICITY; ENZYME STRUCTURE; IC 50; MODEL; NONHUMAN; RABBIT; RETICULOCYTE; TECHNIQUE;

ANIMALS; ARACHIDONATE 12-LIPOXYGENASE; ARACHIDONATE 15-LIPOXYGENASE; BINDING SITES; DATABASES, FACTUAL; HUMANS; LIPOXYGENASE INHIBITORS; MODELS, MOLECULAR; RABBITS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 33144489526     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm050639j     Document Type: Article

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