15-HETE protects rat pulmonary arterial smooth muscle cells from apoptosis via the PI3K/Akt pathway

Prostaglandins and Other Lipid Mediators

Volumn 91, Issue 1-2, 2010, Pages 51-60

  Wang, Shuang ^a   Wang, Yali ^a   Jiang, Jing ^a   Wang, Ruifang ^a   Li, Lisa ^a   Qiu, Zhaoping ^a   Wu, Hong ^c   Zhu, Daling ^a,b  

^a HARBIN MEDICAL UNIVERSITY   (China)

^b Bio pharmaceutical Key Laboratory of Heilongjiang Province   (China)

^c MUDANJIANG MEDICAL UNIVERSITY   (China)

Author keywords

15 Hydroxyeicosatetraenoic acid; Akt; Apoptosis; Hypoxia induced pulmonary hypertension; Rat pulmonary artery muscle smooth cells

Indexed keywords

15 HYDROXYICOSATETRAENOIC ACID; FAS LIGAND; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL NUCLEUS; CELL PROTECTION; CELL STRUCTURE; CELL SURVIVAL; CELL VIABILITY; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVATION; LUNG ARTERY; MEMBRANE DEPOLARIZATION; MITOCHONDRIAL MEMBRANE POTENTIAL; NICK END LABELING; NONHUMAN; RAT; SIGNAL TRANSDUCTION; SMOOTH MUSCLE FIBER; WESTERN BLOTTING;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; APOPTOSIS; BCL-ASSOCIATED DEATH PROTEIN; CELL HYPOXIA; CELL SURVIVAL; FAS LIGAND PROTEIN; GENE EXPRESSION REGULATION; HYDROXYEICOSATETRAENOIC ACIDS; MALE; MITOCHONDRIA; MYOCYTES, SMOOTH MUSCLE; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; PULMONARY ARTERY; RATS; RATS, WISTAR; SIGNAL TRANSDUCTION;

EID: 74849085099     PISSN: 10988823     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.prostaglandins.2009.12.007     Document Type: Article

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