Dynamic switch of negative feedback regulation in Drosophila Akt-TOR signaling

PLoS Genetics

Volumn 6, Issue 6, 2010, Pages 1-17

  Kockel, Lutz ^a,b   Kerr, Kimberly S ^b,e   Melnick, Michael ^c,f   Brückner, Katja ^d   Hebrok, Matthias ^b   Perrimon, Norbert ^a  

^a HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c Beverly MA 01915 USA USA   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

^f CMEA Ventures   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN KINASE B; PROTEIN TORC1; S6 KINASE; TARGET OF RAPAMYCIN KINASE; TARGET OF RAPAMYCIN KINASE COMPLEX 1; TUBERIN; UNCLASSIFIED DRUG; AKT1 PROTEIN, DROSOPHILA; DROSOPHILA PROTEIN; PROTEIN KINASE; TARGET OF RAPAMYCIN PROTEIN, DROSOPHILA;

ANIMAL CELL; ANIMAL CELL CULTURE; ARTICLE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; DEVELOPMENT; DROSOPHILA; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; GENE MUTATION; IMAGE PROCESSING; IMMUNOFLUORESCENCE; IN VIVO STUDY; INSECT CELL; INSECT GENETICS; NEGATIVE FEEDBACK; NONHUMAN; RNA INTERFERENCE; WESTERN BLOTTING; WILD TYPE; ANIMAL; DROSOPHILA MELANOGASTER; GENETIC ASSOCIATION; GENETIC EPISTASIS; GENETICS; METABOLISM; PHOSPHORYLATION; SIGNAL TRANSDUCTION;

ANIMALS; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; ENZYME ACTIVATION; EPISTASIS, GENETIC; GENOME-WIDE ASSOCIATION STUDY; PHOSPHORYLATION; PROTEIN KINASES; PROTO-ONCOGENE PROTEINS C-AKT; RIBOSOMAL PROTEIN S6 KINASES, 70-KDA; SIGNAL TRANSDUCTION;

EID: 77954156681     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1000990     Document Type: Article

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