-
1
-
-
0031919849
-
Jaks and STATs: Biological implications
-
W.J. Leonard, and J.J. O'Shea Jaks and STATs: biological implications Annu Rev Immunol 16 1998 293 322
-
(1998)
Annu Rev Immunol
, vol.16
, pp. 293-322
-
-
Leonard, W.J.1
O'Shea, J.J.2
-
2
-
-
0034012330
-
Regulation of the Jak2 tyrosine kinase by its pseudokinase domain
-
P. Saharinen, K. Takaluoma, and O. Silvennoinen Regulation of the Jak2 tyrosine kinase by its pseudokinase domain Mol Cell Biol 20 2000 3387 3395
-
(2000)
Mol Cell Biol
, vol.20
, pp. 3387-3395
-
-
Saharinen, P.1
Takaluoma, K.2
Silvennoinen, O.3
-
3
-
-
0032425542
-
Janus kinases and focal adhesion kinases play in the 4.1 band: A superfamily of band 4.1 domains important for cell structure and signal transduction
-
J.A. Girault, G. Labesse, J.P. Mornon, and I. Callebaut Janus kinases and focal adhesion kinases play in the 4.1 band: a superfamily of band 4.1 domains important for cell structure and signal transduction Mol Med 4 1998 751 769
-
(1998)
Mol Med
, vol.4
, pp. 751-769
-
-
Girault, J.A.1
Labesse, G.2
Mornon, J.P.3
Callebaut, I.4
-
4
-
-
0034638632
-
Computational and functional analysis of the putative SH2 domain in Janus Kinases
-
D. Kampa, and J. Burnside Computational and functional analysis of the putative SH2 domain in Janus Kinases Biochem Biophys Res Commun 278 2000 175 182
-
(2000)
Biochem Biophys Res Commun
, vol.278
, pp. 175-182
-
-
Kampa, D.1
Burnside, J.2
-
5
-
-
15444339209
-
A TEL-JAK2 fusion protein with constitutive kinase activity in human leukaemia
-
V. Lacronique, A. Boureux, V.D. Valle, H. Poirel, C.T. Quang, and M. Mauchauffe A TEL-JAK2 fusion protein with constitutive kinase activity in human leukaemia Science 278 1997 1309 1312
-
(1997)
Science
, vol.278
, pp. 1309-1312
-
-
Lacronique, V.1
Boureux, A.2
Valle, V.D.3
Poirel, H.4
Quang, C.T.5
Mauchauffe, M.6
-
6
-
-
0030852328
-
Fusion of TEL, the ETS-variant gene 6 (ETV6), to the receptor-associated kinase JAK2 as a result of t(9;12) in a lymphoid and t(9;15;12) in a myeloid leukemia
-
P. Peeters, S.D. Raynaud, J. Cools, I. Wlodarska, J. Grosgeorge, and P. Philip Fusion of TEL, the ETS-variant gene 6 (ETV6), to the receptor-associated kinase JAK2 as a result of t(9;12) in a lymphoid and t(9;15;12) in a myeloid leukemia Blood 90 1997 2535 2540
-
(1997)
Blood
, vol.90
, pp. 2535-2540
-
-
Peeters, P.1
Raynaud, S.D.2
Cools, J.3
Wlodarska, I.4
Grosgeorge, J.5
Philip, P.6
-
7
-
-
25844469587
-
A BCR-JAK2 fusion gene as the result of a t(9;22)(p24;q11.2) translocation in a patient with a clinically typical chronic myeloid leukemia
-
F. Griesinger, H. Hennig, F. Hillmer, M. Podleschny, R. Steffens, and A. Pies A BCR-JAK2 fusion gene as the result of a t(9;22)(p24;q11.2) translocation in a patient with a clinically typical chronic myeloid leukemia Genes Chromosomes Cancer 44 2005 329 333
-
(2005)
Genes Chromosomes Cancer
, vol.44
, pp. 329-333
-
-
Griesinger, F.1
Hennig, H.2
Hillmer, F.3
Podleschny, M.4
Steffens, R.5
Pies, A.6
-
8
-
-
0029898682
-
Oligomerization of the ABL tyrosine kinase by the Ets protein TEL in human leukemia
-
T.R. Golub, A. Goga, G.F. Barker, D.E. Afar, J. McLaughlin, and S.K. Bohlander Oligomerization of the ABL tyrosine kinase by the Ets protein TEL in human leukemia Mol Cell Biol 16 1996 4107 4116
-
(1996)
Mol Cell Biol
, vol.16
, pp. 4107-4116
-
-
Golub, T.R.1
Goga, A.2
Barker, G.F.3
Afar, D.E.4
McLaughlin, J.5
Bohlander, S.K.6
-
9
-
-
0027422977
-
A coiled-coil oligomerization domain of Bcr is essential for the transforming function of Bcr-Abl oncoproteins
-
J.R. McWhirter, D.L. Galasso, and J.Y. Wang A coiled-coil oligomerization domain of Bcr is essential for the transforming function of Bcr-Abl oncoproteins Mol Cell Biol 13 1993 7587 7595
-
(1993)
Mol Cell Biol
, vol.13
, pp. 7587-7595
-
-
McWhirter, J.R.1
Galasso, D.L.2
Wang, J.Y.3
-
10
-
-
20144389913
-
The t(8;9)(p22;p24) is a recurrent abnormality in chronic and acute leukemia that fuses PCM1 to JAK2
-
A. Reiter, C. Walz, A. Watmore, C. Schoch, I. Blau, and B. Schlegelberger The t(8;9)(p22;p24) is a recurrent abnormality in chronic and acute leukemia that fuses PCM1 to JAK2 Cancer Res 65 2005 2662 2667
-
(2005)
Cancer Res
, vol.65
, pp. 2662-2667
-
-
Reiter, A.1
Walz, C.2
Watmore, A.3
Schoch, C.4
Blau, I.5
Schlegelberger, B.6
-
11
-
-
27944481825
-
The t(8;9)(p22;p24) translocation in atypical chronic myeloid leukaemia yields a new PCM1-JAK2 fusion gene
-
M. Bousquet, C. Quelen, V. De Mas, E. Duchayne, B. Roquefeuil, and G. Delsol The t(8;9)(p22;p24) translocation in atypical chronic myeloid leukaemia yields a new PCM1-JAK2 fusion gene Oncogene 24 2005 7248 7252
-
(2005)
Oncogene
, vol.24
, pp. 7248-7252
-
-
Bousquet, M.1
Quelen, C.2
De Mas, V.3
Duchayne, E.4
Roquefeuil, B.5
Delsol, G.6
-
12
-
-
20144363192
-
Acquired mutation of the tyrosine kinase JAK2 in human myeloproliferative disorders
-
E.J. Baxter, L.M. Scott, P.J. Campbell, C. East, N. Fourouclas, and S. Swanton Acquired mutation of the tyrosine kinase JAK2 in human myeloproliferative disorders Lancet 365 2005 1054 1061
-
(2005)
Lancet
, vol.365
, pp. 1054-1061
-
-
Baxter, E.J.1
Scott, L.M.2
Campbell, P.J.3
East, C.4
Fourouclas, N.5
Swanton, S.6
-
13
-
-
17844383458
-
A unique clonal JAK2 mutation leading to constitutive signalling causes polycythaemia vera
-
C. James, V. Ugo, J.P. Le Couedic, J. Staerk, F. Delhommeau, and C. Lacout A unique clonal JAK2 mutation leading to constitutive signalling causes polycythaemia vera Nature 434 2005 1144 1148
-
(2005)
Nature
, vol.434
, pp. 1144-1148
-
-
James, C.1
Ugo, V.2
Le Couedic, J.P.3
Staerk, J.4
Delhommeau, F.5
Lacout, C.6
-
14
-
-
21344440357
-
The JAK2 V617F activating tyrosine kinase mutation is an infrequent event in both "atypical" myeloproliferative disorders and the myelodysplastic syndrome
-
D.P. Steensma, G.W. Dewald, T.L. Lasho, H.L. Powell, R.F. McClure, and R.L. Levine The JAK2 V617F activating tyrosine kinase mutation is an infrequent event in both "atypical" myeloproliferative disorders and the myelodysplastic syndrome Blood 106 2005 1207 1209
-
(2005)
Blood
, vol.106
, pp. 1207-1209
-
-
Steensma, D.P.1
Dewald, G.W.2
Lasho, T.L.3
Powell, H.L.4
McClure, R.F.5
Levine, R.L.6
-
15
-
-
17644424955
-
A gain-of-function mutation of JAK2 in myeloproliferative disorders
-
R. Kralovics, F. Passamonti, A.S. Buser, S.S. Teo, R. Tiedt, and J.R. Passweg A gain-of-function mutation of JAK2 in myeloproliferative disorders N Engl J Med 352 2005 1779 1790
-
(2005)
N Engl J Med
, vol.352
, pp. 1779-1790
-
-
Kralovics, R.1
Passamonti, F.2
Buser, A.S.3
Teo, S.S.4
Tiedt, R.5
Passweg, J.R.6
-
16
-
-
20244369569
-
Activating mutation in the tyrosine kinase JAK2 in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis
-
R.L. Levine, M. Wadleigh, J. Cools, B.L. Ebert, G. Wernig, and B.J. Huntly Activating mutation in the tyrosine kinase JAK2 in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis Cancer Cell 7 2005 387 397
-
(2005)
Cancer Cell
, vol.7
, pp. 387-397
-
-
Levine, R.L.1
Wadleigh, M.2
Cools, J.3
Ebert, B.L.4
Wernig, G.5
Huntly, B.J.6
-
17
-
-
20744460045
-
Identification of an acquired JAK2 mutation in polycythemia vera
-
R. Zhao, S. Xing, Z. Li, X. Fu, Q. Li, and S.B. Krantz Identification of an acquired JAK2 mutation in polycythemia vera J Biol Chem 280 2005 22788 22792
-
(2005)
J Biol Chem
, vol.280
, pp. 22788-22792
-
-
Zhao, R.1
Xing, S.2
Li, Z.3
Fu, X.4
Li, Q.5
Krantz, S.B.6
-
18
-
-
0037428669
-
Hodgkin's lymphoma cell lines are characterized by frequent aberrations on chromosomes 2p and 9p including REL and JAK2
-
S. Joos, M. Granzow, H. Holtgreve-Grez, R. Siebert, L. Harder, and J.I. Martin-Subero Hodgkin's lymphoma cell lines are characterized by frequent aberrations on chromosomes 2p and 9p including REL and JAK2 Int J Cancer 103 2003 489 495
-
(2003)
Int J Cancer
, vol.103
, pp. 489-495
-
-
Joos, S.1
Granzow, M.2
Holtgreve-Grez, H.3
Siebert, R.4
Harder, L.5
Martin-Subero, J.I.6
-
19
-
-
0030840464
-
STATs and gene regulation
-
J.E. Darnell Jr. STATs and gene regulation Science 277 1997 1630 1635
-
(1997)
Science
, vol.277
, pp. 1630-1635
-
-
Darnell Jr., J.E.1
-
20
-
-
0031037363
-
Nuclear integration of JAK/STAT and Ras/AP-1 signaling by CBP and p300
-
A.E. Horvai, L. Xu, E. Korzus, G. Brard, D. Kalafus, and T.M. Mullen Nuclear integration of JAK/STAT and Ras/AP-1 signaling by CBP and p300 Proc Natl Acad Sci USA 94 1997 1074 1079
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 1074-1079
-
-
Horvai, A.E.1
Xu, L.2
Korzus, E.3
Brard, G.4
Kalafus, D.5
Mullen, T.M.6
-
21
-
-
0030449174
-
Two contact regions between Stat1 and CBP/p300 in interferon gamma signaling
-
J.J. Zhang, U. Vinkemeier, W. Gu, D. Chakravarti, C.M. Horvath, and J.E. Darnell Jr. Two contact regions between Stat1 and CBP/p300 in interferon gamma signaling Proc Natl Acad Sci USA 93 1996 15092 15096
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 15092-15096
-
-
Zhang, J.J.1
Vinkemeier, U.2
Gu, W.3
Chakravarti, D.4
Horvath, C.M.5
Darnell Jr., J.E.6
-
22
-
-
0034658024
-
Serine phosphorylation of STATs
-
T. Decker, and P. Kovarik Serine phosphorylation of STATs Oncogene 19 2000 2628 2637
-
(2000)
Oncogene
, vol.19
, pp. 2628-2637
-
-
Decker, T.1
Kovarik, P.2
-
23
-
-
0037184052
-
An LXXLL motif in the transactivation domain of STAT6 mediates recruitment of NCoA-1/SRC-1
-
C.M. Litterst, and E. Pfitzner An LXXLL motif in the transactivation domain of STAT6 mediates recruitment of NCoA-1/SRC-1 J Biol Chem 277 2002 36052 36060
-
(2002)
J Biol Chem
, vol.277
, pp. 36052-36060
-
-
Litterst, C.M.1
Pfitzner, E.2
-
24
-
-
17644374227
-
The transcriptional co-activator protein p100 recruits histone acetyltransferase activity to STAT6 and mediates interaction between the CREB-binding protein and STAT6
-
T. Valineva, J. Yang, R. Palovuori, and O. Silvennoinen The transcriptional co-activator protein p100 recruits histone acetyltransferase activity to STAT6 and mediates interaction between the CREB-binding protein and STAT6 J Biol Chem 280 2005 14989 14996
-
(2005)
J Biol Chem
, vol.280
, pp. 14989-14996
-
-
Valineva, T.1
Yang, J.2
Palovuori, R.3
Silvennoinen, O.4
-
25
-
-
0036251154
-
Stat proteins and oncogenesis
-
J. Bromberg Stat proteins and oncogenesis J Clin Invest 109 2002 1139 1142
-
(2002)
J Clin Invest
, vol.109
, pp. 1139-1142
-
-
Bromberg, J.1
-
26
-
-
0032984589
-
Constitutive activation of Stat3 signaling confers resistance to apoptosis in human U266 myeloma cells
-
R. Catlett-Falcone, T.H. Landowski, M.M. Oshiro, J. Turkson, A. Levitzki, and R. Savino Constitutive activation of Stat3 signaling confers resistance to apoptosis in human U266 myeloma cells Immunity 10 1999 105 115
-
(1999)
Immunity
, vol.10
, pp. 105-115
-
-
Catlett-Falcone, R.1
Landowski, T.H.2
Oshiro, M.M.3
Turkson, J.4
Levitzki, A.5
Savino, R.6
-
27
-
-
2442663092
-
Activated signal transducer and activator of transcription (STAT) 3 localization in focal adhesions and function in ovarian cancer cell motility
-
D.L. Silver, H. Naora, J. Liu, W. Cheng, and D.J. Montell Activated signal transducer and activator of transcription (STAT) 3 localization in focal adhesions and function in ovarian cancer cell motility Cancer Res 64 2004 3550 3558
-
(2004)
Cancer Res
, vol.64
, pp. 3550-3558
-
-
Silver, D.L.1
Naora, H.2
Liu, J.3
Cheng, W.4
Montell, D.J.5
-
28
-
-
1242292306
-
STAT-1: A novel regulator of apoptosis
-
A. Stephanou, and D.S. Latchman STAT-1: a novel regulator of apoptosis Int J Exp Pathol 84 2003 239 244
-
(2003)
Int J Exp Pathol
, vol.84
, pp. 239-244
-
-
Stephanou, A.1
Latchman, D.S.2
-
29
-
-
0029059985
-
Human protein tyrosine phosphatase 1C (PTPN6) gene structure: Alternate promoter usage and exon skipping generate multiple transcripts
-
D. Banville, R. Stocco, and S.H. Shen Human protein tyrosine phosphatase 1C (PTPN6) gene structure: alternate promoter usage and exon skipping generate multiple transcripts Genomics 27 1995 165 173
-
(1995)
Genomics
, vol.27
, pp. 165-173
-
-
Banville, D.1
Stocco, R.2
Shen, S.H.3
-
30
-
-
0345357773
-
Gene silencing in cancer in association with promoter hypermethylation
-
J.G. Herman, and S.B. Baylin Gene silencing in cancer in association with promoter hypermethylation N Engl J Med 349 2003 2042 2054
-
(2003)
N Engl J Med
, vol.349
, pp. 2042-2054
-
-
Herman, J.G.1
Baylin, S.B.2
-
31
-
-
0032960181
-
Cancer epigenetics comes of age
-
P.A. Jones, and P.W. Laird Cancer epigenetics comes of age Nat Genet 21 1999 163 167
-
(1999)
Nat Genet
, vol.21
, pp. 163-167
-
-
Jones, P.A.1
Laird, P.W.2
-
32
-
-
0037112439
-
Gene silencing of the tyrosine phosphatase SHP1 gene by aberrant methylation in leukemias/lymphomas
-
T. Oka, M. Ouchida, M. Koyama, Y. Ogama, S. Takada, and Y. Nakatani Gene silencing of the tyrosine phosphatase SHP1 gene by aberrant methylation in leukemias/lymphomas Cancer Res 62 2002 6390 6394
-
(2002)
Cancer Res
, vol.62
, pp. 6390-6394
-
-
Oka, T.1
Ouchida, M.2
Koyama, M.3
Ogama, Y.4
Takada, S.5
Nakatani, Y.6
-
33
-
-
18744395503
-
STAT3- and DNA methyltransferase 1-mediated epigenetic silencing of SHP-1 tyrosine phosphatase tumor suppressor gene in malignant T lymphocytes
-
Q. Zhang, H.Y. Wang, M. Marzec, P.N. Raghunath, T. Nagasawa, and M.A. Wasik STAT3- and DNA methyltransferase 1-mediated epigenetic silencing of SHP-1 tyrosine phosphatase tumor suppressor gene in malignant T lymphocytes Proc Natl Acad Sci USA 102 2005 6948 6953
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 6948-6953
-
-
Zhang, Q.1
Wang, H.Y.2
Marzec, M.3
Raghunath, P.N.4
Nagasawa, T.5
Wasik, M.A.6
-
34
-
-
2942584857
-
SOCS1 and SHP1 hypermethylation in multiple myeloma: Implications for epigenetic activation of the Jak/STAT pathway
-
C.S. Chim, T.K. Fung, W.C. Cheung, R. Liang, and Y.L. Kwong SOCS1 and SHP1 hypermethylation in multiple myeloma: implications for epigenetic activation of the Jak/STAT pathway Blood 103 2004 4630 4635
-
(2004)
Blood
, vol.103
, pp. 4630-4635
-
-
Chim, C.S.1
Fung, T.K.2
Cheung, W.C.3
Liang, R.4
Kwong, Y.L.5
-
35
-
-
17144366936
-
Aberrant methylation of the negative regulators RASSFIA SHP-1 and SOCS-1 in myelodysplastic syndromes and acute myeloid leukaemia
-
M.F. Johan, D.T. Bowen, M.E. Frew, A.C. Goodeve, and J.T. Reilly Aberrant methylation of the negative regulators RASSFIA SHP-1 and SOCS-1 in myelodysplastic syndromes and acute myeloid leukaemia Br J Haematol 129 2005 60 65
-
(2005)
Br J Haematol
, vol.129
, pp. 60-65
-
-
Johan, M.F.1
Bowen, D.T.2
Frew, M.E.3
Goodeve, A.C.4
Reilly, J.T.5
-
36
-
-
12144290834
-
The role of the inhibitors of interleukin-6 signal transduction SHP2 and SOCS3 for desensitization of interleukin-6 signalling
-
P. Fischer, U. Lehmann, R.M. Sobota, J. Schmitz, C. Niemand, and S. Linnemann The role of the inhibitors of interleukin-6 signal transduction SHP2 and SOCS3 for desensitization of interleukin-6 signalling Biochem J 378 2004 449 460
-
(2004)
Biochem J
, vol.378
, pp. 449-460
-
-
Fischer, P.1
Lehmann, U.2
Sobota, R.M.3
Schmitz, J.4
Niemand, C.5
Linnemann, S.6
-
38
-
-
4043056497
-
Mouse model of Noonan syndrome reveals cell type- and gene dosage-dependent effects of Ptpn11 mutation
-
T. Araki, M.G. Mohi, F.A. Ismat, R.T. Bronson, I.R. Williams, and J.L. Kutok Mouse model of Noonan syndrome reveals cell type- and gene dosage-dependent effects of Ptpn11 mutation Nat Med 10 2004 849 857
-
(2004)
Nat Med
, vol.10
, pp. 849-857
-
-
Araki, T.1
Mohi, M.G.2
Ismat, F.A.3
Bronson, R.T.4
Williams, I.R.5
Kutok, J.L.6
-
39
-
-
0038278866
-
Somatic mutations in PTPN11 in juvenile myelomonocytic leukemia, myelodysplastic syndromes and acute myeloid leukemia
-
M. Tartaglia, C.M. Niemeyer, A. Fragale, X. Song, J. Buechner, and A. Jung Somatic mutations in PTPN11 in juvenile myelomonocytic leukemia, myelodysplastic syndromes and acute myeloid leukemia Nat Genet 34 2003 148 150
-
(2003)
Nat Genet
, vol.34
, pp. 148-150
-
-
Tartaglia, M.1
Niemeyer, C.M.2
Fragale, A.3
Song, X.4
Buechner, J.5
Jung, A.6
-
40
-
-
0028346560
-
CD45: An emerging role as a protein tyrosine phosphatase required for lymphocyte activation and development
-
I.S. Trowbridge, and M.L. Thomas CD45: an emerging role as a protein tyrosine phosphatase required for lymphocyte activation and development Annu Rev Immunol 12 1994 85 116
-
(1994)
Annu Rev Immunol
, vol.12
, pp. 85-116
-
-
Trowbridge, I.S.1
Thomas, M.L.2
-
41
-
-
0038815306
-
CD45: A critical regulator of signaling thresholds in immune cells
-
M.L. Hermiston, Z. Xu, and A. Weiss CD45: a critical regulator of signaling thresholds in immune cells Annu Rev Immunol 21 2003 107 137
-
(2003)
Annu Rev Immunol
, vol.21
, pp. 107-137
-
-
Hermiston, M.L.1
Xu, Z.2
Weiss, A.3
-
42
-
-
0026584285
-
The nontransmembrane tyrosine phosphatase PTP-1B localizes to the endoplasmic reticulum via its 35 amino acid C-terminal sequence
-
J.V. Frangioni, P.H. Beahm, V. Shifrin, C.A. Jost, and B.G. Neel The nontransmembrane tyrosine phosphatase PTP-1B localizes to the endoplasmic reticulum via its 35 amino acid C-terminal sequence Cell 68 1992 545 560
-
(1992)
Cell
, vol.68
, pp. 545-560
-
-
Frangioni, J.V.1
Beahm, P.H.2
Shifrin, V.3
Jost, C.A.4
Neel, B.G.5
-
43
-
-
0036318564
-
Identification of a nuclear Stat1 protein tyrosine phosphatase
-
J. ten Hoeve, M. de Jesus Ibarra-Sanchez, Y. Fu, W. Zhu, M. Tremblay, and M. David Identification of a nuclear Stat1 protein tyrosine phosphatase Mol Cell Biol 22 2002 5662 5668
-
(2002)
Mol Cell Biol
, vol.22
, pp. 5662-5668
-
-
Ten Hoeve, J.1
De Jesus Ibarra-Sanchez, M.2
Fu, Y.3
Zhu, W.4
Tremblay, M.5
David, M.6
-
44
-
-
0037022564
-
Members of the PIAS family act as SUMO ligases for c-Jun and p53 and repress p53 activity
-
D. Schmidt, and S. Muller Members of the PIAS family act as SUMO ligases for c-Jun and p53 and repress p53 activity Proc Natl Acad Sci USA 99 2002 2872 2877
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 2872-2877
-
-
Schmidt, D.1
Muller, S.2
-
45
-
-
23444461182
-
Regulation of gene-activation pathways by PIAS proteins in the immune system
-
K. Shuai, and B. Liu Regulation of gene-activation pathways by PIAS proteins in the immune system Nat Rev Immunol 5 2005 593 605
-
(2005)
Nat Rev Immunol
, vol.5
, pp. 593-605
-
-
Shuai, K.1
Liu, B.2
-
46
-
-
0032169599
-
Inhibition of Stat1-mediated gene activation by PIAS1
-
B. Liu, J. Liao, X. Rao, S.A. Kushner, C.D. Chung, and D.D. Change Inhibition of Stat1-mediated gene activation by PIAS1 Proc Natl Acad Sci USA 95 1998 10626 10631
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 10626-10631
-
-
Liu, B.1
Liao, J.2
Rao, X.3
Kushner, S.A.4
Chung, C.D.5
Change, D.D.6
-
47
-
-
0030725378
-
Specific inhibition of Stat3 signal transduction by PIAS3
-
C.D. Chung, J. Liao, B. Liu, X. Rao, P. Jay, and P. Perte Specific inhibition of Stat3 signal transduction by PIAS3 Science 278 1997 1803 1805
-
(1997)
Science
, vol.278
, pp. 1803-1805
-
-
Chung, C.D.1
Liao, J.2
Liu, B.3
Rao, X.4
Jay, P.5
Perte, P.6
-
48
-
-
0035853098
-
A transcriptional corepressor of Stat1 with an essential LXXLL signature motif
-
B. Liu, M. Gross, J. ten Hoeve, and K. Shuai A transcriptional corepressor of Stat1 with an essential LXXLL signature motif Proc Natl Acad Sci USA 98 2001 3203 3207
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 3203-3207
-
-
Liu, B.1
Gross, M.2
Ten Hoeve, J.3
Shuai, K.4
-
49
-
-
0037677203
-
PIASx is a transcriptional co-repressor of signal transducer and activator of transcription 4
-
T. Aurora, B. Liu, H. He, J. Kim, T.L. Murphy, and K.M. Murphy PIASx is a transcriptional co-repressor of signal transducer and activator of transcription 4 J Biol Chem 278 2003 21327 21330
-
(2003)
J Biol Chem
, vol.278
, pp. 21327-21330
-
-
Aurora, T.1
Liu, B.2
He, H.3
Kim, J.4
Murphy, T.L.5
Murphy, K.M.6
-
50
-
-
4644367257
-
PIAS1 selectively inhibits interferon-inducible genes and is important in innate immunity
-
B. Liu, S. Mink, K.A. Wong, N. Stein, C. German, and P.W. Dempsey PIAS1 selectively inhibits interferon-inducible genes and is important in innate immunity Nat Immunol 5 2004 891 898
-
(2004)
Nat Immunol
, vol.5
, pp. 891-898
-
-
Liu, B.1
Mink, S.2
Wong, K.A.3
Stein, N.4
German, C.5
Dempsey, P.W.6
-
51
-
-
8444253635
-
PIASy-deficient mice display modest defects in IFN and Wnt signalling
-
W. Roth, C. Dustman, M. Kieslinger, A. Gilmozzi, D. Irmer, and E. Kremmer PIASy-deficient mice display modest defects in IFN and Wnt signalling J Immunol 173 2004 6189 6199
-
(2004)
J Immunol
, vol.173
, pp. 6189-6199
-
-
Roth, W.1
Dustman, C.2
Kieslinger, M.3
Gilmozzi, A.4
Irmer, D.5
Kremmer, E.6
-
52
-
-
0036134884
-
Multilevel dysregulation of STAT3 activation in anaplastic lymphoma kinase-positive T/null-cell lymphoma
-
Q. Zhang, P.N. Raghunath, L. Xue, M. Majewski, D.F. Carpentieri, and N. Odum Multilevel dysregulation of STAT3 activation in anaplastic lymphoma kinase-positive T/null-cell lymphoma J Immunol 168 2002 466 474
-
(2002)
J Immunol
, vol.168
, pp. 466-474
-
-
Zhang, Q.1
Raghunath, P.N.2
Xue, L.3
Majewski, M.4
Carpentieri, D.F.5
Odum, N.6
-
53
-
-
0142215552
-
DNA microarray analysis of stage progression mechanism in myelodysplastic syndrome
-
M. Ueda, J. Ota, Y. Yamashita, Y.L. Choi, R. Ohki, and T. Wada DNA microarray analysis of stage progression mechanism in myelodysplastic syndrome Br J Haematol 123 2003 288 296
-
(2003)
Br J Haematol
, vol.123
, pp. 288-296
-
-
Ueda, M.1
Ota, J.2
Yamashita, Y.3
Choi, Y.L.4
Ohki, R.5
Wada, T.6
-
54
-
-
0029014206
-
A novel cytokine-inducible gene CIS encodes an SH2-containing protein that binds to tyrosine-phosphorylated interleukin 3 and erythropoietin receptors
-
A. Yoshimura, T. Ohkubo, T. Kiguchi, N.A. Jenkins, D.J. Gilbert, and N.G. Copeland A novel cytokine-inducible gene CIS encodes an SH2-containing protein that binds to tyrosine-phosphorylated interleukin 3 and erythropoietin receptors Embo J 14 1995 2816 2826
-
(1995)
Embo J
, vol.14
, pp. 2816-2826
-
-
Yoshimura, A.1
Ohkubo, T.2
Kiguchi, T.3
Jenkins, N.A.4
Gilbert, D.J.5
Copeland, N.G.6
-
55
-
-
0032561322
-
Proteasomes regulate erythropoietin receptor and signal transducer and activator of transcription 5 (STAT5) activation Possible involvement of the ubiquitinated Cis protein
-
F. Verdier, S. Chretien, O. Muller, P. Varlet, A. Yoshimura, and S. Gisselbrecht Proteasomes regulate erythropoietin receptor and signal transducer and activator of transcription 5 (STAT5) activation Possible involvement of the ubiquitinated Cis protein J Biol Chem 273 1998 28185 28190
-
(1998)
J Biol Chem
, vol.273
, pp. 28185-28190
-
-
Verdier, F.1
Chretien, S.2
Muller, O.3
Varlet, P.4
Yoshimura, A.5
Gisselbrecht, S.6
-
56
-
-
0030792590
-
A family of cytokine-inducible inhibitors of signalling
-
R. Starr, T.A. Willson, E.M. Viney, L.J. Murray, J.R. Rayner, and B.J. Jenkins A family of cytokine-inducible inhibitors of signalling Nature 387 1997 917 921
-
(1997)
Nature
, vol.387
, pp. 917-921
-
-
Starr, R.1
Willson, T.A.2
Viney, E.M.3
Murray, L.J.4
Rayner, J.R.5
Jenkins, B.J.6
-
57
-
-
0030839112
-
A new protein containing an SH2 domain that inhibits JAK kinases
-
T.A. Endo, M. Masuhara, M. Yokouchi, R. Suzuki, H. Sakamoto, and K. Mitsui A new protein containing an SH2 domain that inhibits JAK kinases Nature 387 1997 921 924
-
(1997)
Nature
, vol.387
, pp. 921-924
-
-
Endo, T.A.1
Masuhara, M.2
Yokouchi, M.3
Suzuki, R.4
Sakamoto, H.5
Mitsui, K.6
-
58
-
-
0030755934
-
Structure and function of a new STAT-induced STAT inhibitor
-
T. Naka, M. Narazaki, M. Hirata, T. Matsumoto, S. Minamoto, and A. Aono Structure and function of a new STAT-induced STAT inhibitor Nature 387 1997 924 929
-
(1997)
Nature
, vol.387
, pp. 924-929
-
-
Naka, T.1
Narazaki, M.2
Hirata, M.3
Matsumoto, T.4
Minamoto, S.5
Aono, A.6
-
59
-
-
0034724677
-
SOCS3 exerts its inhibitory function on interleukin-6 signal transduction through the SHP2 recruitment site of gp130
-
J. Schmitz, M. Weissenbach, S. Haan, P.C. Heinrich, and F. Schaper SOCS3 exerts its inhibitory function on interleukin-6 signal transduction through the SHP2 recruitment site of gp130 J Biol Chem 275 2000 12848 12856
-
(2000)
J Biol Chem
, vol.275
, pp. 12848-12856
-
-
Schmitz, J.1
Weissenbach, M.2
Haan, S.3
Heinrich, P.C.4
Schaper, F.5
-
60
-
-
0037174816
-
Biological evidence that SOCS-2 can act either as an enhancer or suppressor of growth hormone signaling
-
C.J. Greenhalgh, D. Metcalf, A.L. Thaus, J.E. Corbin, R. Uren, and P.O. Morgan Biological evidence that SOCS-2 can act either as an enhancer or suppressor of growth hormone signaling J Biol Chem 277 2002 40181 40184
-
(2002)
J Biol Chem
, vol.277
, pp. 40181-40184
-
-
Greenhalgh, C.J.1
Metcalf, D.2
Thaus, A.L.3
Corbin, J.E.4
Uren, R.5
Morgan, P.O.6
-
61
-
-
0036558025
-
The SOCS box: A tale of destruction and degradation
-
B.T. Kile, B.A. Schulman, W.S. Alexander, N.A. Nicola, H.M. Martin, and D.J. Hilton The SOCS box: a tale of destruction and degradation Trends Biochem Sci 27 2002 235 241
-
(2002)
Trends Biochem Sci
, vol.27
, pp. 235-241
-
-
Kile, B.T.1
Schulman, B.A.2
Alexander, W.S.3
Nicola, N.A.4
Martin, H.M.5
Hilton, D.J.6
-
62
-
-
0033558088
-
Socs1 binds to multiple signalling proteins and suppresses steel factor-dependent proliferation
-
P. De Sepulveda, K. Okkenhaug, J.L. Rose, R.G. Hawley, P. Dubreuil, and R. Rottapel Socs1 binds to multiple signalling proteins and suppresses steel factor-dependent proliferation Embo J 18 1999 904 915
-
(1999)
Embo J
, vol.18
, pp. 904-915
-
-
De Sepulveda, P.1
Okkenhaug, K.2
Rose, J.L.3
Hawley, R.G.4
Dubreuil, P.5
Rottapel, R.6
-
63
-
-
0036233985
-
Regulation of Jak2 through the ubiquitin-proteasome pathway involves phosphorylation of Jak2 on Y1007 and interaction with SOCS-1
-
D. Ungureanu, P. Saharinen, I. Junttila, D.J. Hilton, and O. Silvennoinen Regulation of Jak2 through the ubiquitin-proteasome pathway involves phosphorylation of Jak2 on Y1007 and interaction with SOCS-1 Mol Cell Biol 22 2002 3316 3326
-
(2002)
Mol Cell Biol
, vol.22
, pp. 3316-3326
-
-
Ungureanu, D.1
Saharinen, P.2
Junttila, I.3
Hilton, D.J.4
Silvennoinen, O.5
-
64
-
-
0035918239
-
The SOCS box of SOCS-1 accelerates ubiquitin-dependent proteolysis of TEL-JAK2
-
S. Kamizono, T. Hanada, H. Yasukawa, S. Minoguchi, R. Kato, and M. Minoguchi The SOCS box of SOCS-1 accelerates ubiquitin-dependent proteolysis of TEL-JAK2 J Biol Chem 276 2001 12530 12538
-
(2001)
J Biol Chem
, vol.276
, pp. 12530-12538
-
-
Kamizono, S.1
Hanada, T.2
Yasukawa, H.3
Minoguchi, S.4
Kato, R.5
Minoguchi, M.6
-
65
-
-
0035036625
-
Socs-1 inhibits TEL-JAK2-mediated transformation of hematopoietic cells through inhibition of JAK2 kinase activity and induction of proteasome-mediated degradation
-
J. Frantsve, J. Schwaller, D.W. Sternberg, J. Kutok, and D.G. Gilliland Socs-1 inhibits TEL-JAK2-mediated transformation of hematopoietic cells through inhibition of JAK2 kinase activity and induction of proteasome-mediated degradation Mol Cell Biol 21 2001 3547 3557
-
(2001)
Mol Cell Biol
, vol.21
, pp. 3547-3557
-
-
Frantsve, J.1
Schwaller, J.2
Sternberg, D.W.3
Kutok, J.4
Gilliland, D.G.5
-
66
-
-
0036830636
-
SOCS-1 and SOCS-3 block insulin signaling by ubiquitin-mediated degradation of IRS1 and IRS2
-
L. Rui, M. Yuan, D. Frantz, S. Shoelson, and M.F. White SOCS-1 and SOCS-3 block insulin signaling by ubiquitin-mediated degradation of IRS1 and IRS2 J Biol Chem 277 2002 42394 42398
-
(2002)
J Biol Chem
, vol.277
, pp. 42394-42398
-
-
Rui, L.1
Yuan, M.2
Frantz, D.3
Shoelson, S.4
White, M.F.5
-
67
-
-
0141865509
-
Negative regulation of FAK signaling by SOCS proteins
-
E. Liu, J.F. Cote, and K. Vuori Negative regulation of FAK signaling by SOCS proteins Embo J 22 2003 5036 5046
-
(2003)
Embo J
, vol.22
, pp. 5036-5046
-
-
Liu, E.1
Cote, J.F.2
Vuori, K.3
-
68
-
-
17944383969
-
A sequence of the CIS gene promoter interacts preferentially with two associated STAT5A dimers: A distinct biochemical difference between STAT5A and STAT5B
-
F. Verdier, R. Rabionet, F. Gouilleux, C. Beisenherz-Huss, P. Varlet, and O. Muller A sequence of the CIS gene promoter interacts preferentially with two associated STAT5A dimers: a distinct biochemical difference between STAT5A and STAT5B Mol Cell Biol 18 1998 5852 5860
-
(1998)
Mol Cell Biol
, vol.18
, pp. 5852-5860
-
-
Verdier, F.1
Rabionet, R.2
Gouilleux, F.3
Beisenherz-Huss, C.4
Varlet, P.5
Muller, O.6
-
69
-
-
0034120709
-
IFN regulatory factor-1-mediated transcriptional activation of mouse STAT-induced STAT inhibitor-1 gene promoter by IFN-gamma
-
H. Saito, Y. Morita, M. Fujimoto, M. Narazaki, T. Naka, and T. Kishimoto IFN regulatory factor-1-mediated transcriptional activation of mouse STAT-induced STAT inhibitor-1 gene promoter by IFN-gamma J Immunol 164 2000 5833 5843
-
(2000)
J Immunol
, vol.164
, pp. 5833-5843
-
-
Saito, H.1
Morita, Y.2
Fujimoto, M.3
Narazaki, M.4
Naka, T.5
Kishimoto, T.6
-
70
-
-
0345447641
-
IL-4 and IL-13 Induce SOCS-1 Gene Expression in A549 Cells by Three Functional STAT6-Binding Motifs Located Upstream of the Transcription Initiation Site
-
D. Hebenstreit, P. Luft, A. Schmiedlechner, G. Regl, A.M. Frischauf, and F. Aberger IL-4 and IL-13 Induce SOCS-1 Gene Expression in A549 Cells by Three Functional STAT6-Binding Motifs Located Upstream of the Transcription Initiation Site J Immunol 171 2003 5901 5907
-
(2003)
J Immunol
, vol.171
, pp. 5901-5907
-
-
Hebenstreit, D.1
Luft, P.2
Schmiedlechner, A.3
Regl, G.4
Frischauf, A.M.5
Aberger, F.6
-
71
-
-
4143105721
-
STAT6 and Ets-1 form a stable complex that modulates SOCS-1 expression by IL-4 in keratinocytes
-
J. Travagli, M. Letourneur, J. Bertoglio, and J. Pierre STAT6 and Ets-1 form a stable complex that modulates SOCS-1 expression by IL-4 in keratinocytes J Biol Chem 279 2004 35182 35192
-
(2004)
J Biol Chem
, vol.279
, pp. 35182-35192
-
-
Travagli, J.1
Letourneur, M.2
Bertoglio, J.3
Pierre, J.4
-
72
-
-
13044263097
-
The conserved SOCS box motif in suppressors of cytokine signaling binds to elongins B and C and may couple bound proteins to proteasomal degradation
-
J.G. Zhang, A. Farley, S.E. Nicholson, T.A. Willson, L.M. Zugaro, and R.J. Simpson The conserved SOCS box motif in suppressors of cytokine signaling binds to elongins B and C and may couple bound proteins to proteasomal degradation Proc Natl Acad Sci USA 96 1996 2071 2076
-
(1996)
Proc Natl Acad Sci USA
, vol.96
, pp. 2071-2076
-
-
Zhang, J.G.1
Farley, A.2
Nicholson, S.E.3
Willson, T.A.4
Zugaro, L.M.5
Simpson, R.J.6
-
73
-
-
4744363325
-
SOCS-1 localizes to the microtubule organizing complex-associated 20S proteasome
-
B.Q. Vuong, T.L. Arenzana, B.M. Showalter, J. Losman, X.P. Chen, and J. Mostecki SOCS-1 localizes to the microtubule organizing complex-associated 20S proteasome Mol Cell Biol 24 2004 9092 9101
-
(2004)
Mol Cell Biol
, vol.24
, pp. 9092-9101
-
-
Vuong, B.Q.1
Arenzana, T.L.2
Showalter, B.M.3
Losman, J.4
Chen, X.P.5
Mostecki, J.6
-
74
-
-
0037133208
-
Pim serine/threonine kinases regulate the stability of Socs-1 protein
-
X.P. Chen, J.A. Losman, S. Cowan, E. Donahue, S. Fay, and B.Q. Vuong Pim serine/threonine kinases regulate the stability of Socs-1 protein Proc Natl Acad Sci USA 99 2002 2175 2180
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 2175-2180
-
-
Chen, X.P.1
Losman, J.A.2
Cowan, S.3
Donahue, E.4
Fay, S.5
Vuong, B.Q.6
-
75
-
-
0035040971
-
Knocking the SOCS off a tumor suppressor
-
T. Kishimoto, and H. Kikutani Knocking the SOCS off a tumor suppressor Nat Genet 28 2001 4 5
-
(2001)
Nat Genet
, vol.28
, pp. 4-5
-
-
Kishimoto, T.1
Kikutani, H.2
-
76
-
-
0037182762
-
The tumor suppressor activity of SOCS-1
-
R. Rottapel, S. Ilangumaran, C. Neale, J. La Rose, J.M. Ho, and M.H. Nguyen The tumor suppressor activity of SOCS-1 Oncogene 21 2002 4351 4362
-
(2002)
Oncogene
, vol.21
, pp. 4351-4362
-
-
Rottapel, R.1
Ilangumaran, S.2
Neale, C.3
La Rose, J.4
Ho, J.M.5
Nguyen, M.H.6
-
77
-
-
0037127270
-
Regulation of Socs gene expression by the proto-oncoprotein GFI-1B: Two routes for STAT5 target gene induction by erythropoietin
-
A.G. Jegalian, and H. Wu Regulation of Socs gene expression by the proto-oncoprotein GFI-1B: two routes for STAT5 target gene induction by erythropoietin J Biol Chem 277 2002 2345 2352
-
(2002)
J Biol Chem
, vol.277
, pp. 2345-2352
-
-
Jegalian, A.G.1
Wu, H.2
-
78
-
-
26244462644
-
Hepatitis C virus core protein exerts an inhibitory effect on suppressor of cytokine signaling (SOCS)-1 gene expression
-
H. Miyoshi, H. Fujie, Y. Shintani, T. Tsutsumi, S. Shinzawa, and M. Makuuchi Hepatitis C virus core protein exerts an inhibitory effect on suppressor of cytokine signaling (SOCS)-1 gene expression J Hepatol 43 2005 757 763
-
(2005)
J Hepatol
, vol.43
, pp. 757-763
-
-
Miyoshi, H.1
Fujie, H.2
Shintani, Y.3
Tsutsumi, T.4
Shinzawa, S.5
Makuuchi, M.6
-
79
-
-
3242881890
-
Methylation status of suppressor of cytokine signaling-1 gene in hepatocellular carcinoma
-
H. Miyoshi, H. Fujie, K. Moriya, Y. Shintani, T. Tsutsumi, and M. Makuuchi Methylation status of suppressor of cytokine signaling-1 gene in hepatocellular carcinoma J Gastroenterol 39 2004 563 569
-
(2004)
J Gastroenterol
, vol.39
, pp. 563-569
-
-
Miyoshi, H.1
Fujie, H.2
Moriya, K.3
Shintani, Y.4
Tsutsumi, T.5
Makuuchi, M.6
-
80
-
-
0035042611
-
SOCS-1, a negative regulator of the JAK/STAT pathway, is silenced by methylation in human hepatocellular carcinoma and shows growth-suppression activity
-
H. Yoshikawa, K. Matsubara, G.S. Qian, P. Jackson, J.D. Groopman, and J.E. Manning SOCS-1, a negative regulator of the JAK/STAT pathway, is silenced by methylation in human hepatocellular carcinoma and shows growth-suppression activity Nat Genet 28 2001 29 35
-
(2001)
Nat Genet
, vol.28
, pp. 29-35
-
-
Yoshikawa, H.1
Matsubara, K.2
Qian, G.S.3
Jackson, P.4
Groopman, J.D.5
Manning, J.E.6
-
81
-
-
0242610382
-
Methylation-mediated silencing of SOCS-1 gene in hepatocellular carcinoma derived from cirrhosis
-
O. Okochi, K. Hibi, M. Sakai, S. Inoue, S. Takeda, and T. Kaneko Methylation-mediated silencing of SOCS-1 gene in hepatocellular carcinoma derived from cirrhosis Clin Cancer Res 9 2003 5295 5298
-
(2003)
Clin Cancer Res
, vol.9
, pp. 5295-5298
-
-
Okochi, O.1
Hibi, K.2
Sakai, M.3
Inoue, S.4
Takeda, S.5
Kaneko, T.6
-
82
-
-
0035503704
-
CpG methylation as a basis for breast tumor-specific loss of NES1/kallikrein 10 expression
-
B. Li, J. Goyal, S. Dhar, G. Dimri, E. Evron, and S. Sukumar CpG methylation as a basis for breast tumor-specific loss of NES1/kallikrein 10 expression Cancer Res 61 2001 8014 8021
-
(2001)
Cancer Res
, vol.61
, pp. 8014-8021
-
-
Li, B.1
Goyal, J.2
Dhar, S.3
Dimri, G.4
Evron, E.5
Sukumar, S.6
-
83
-
-
0042575343
-
Aberrant methylation of suppressor of cytokine signalling-1 (SOCS-1) gene in pancreatic ductal neoplasms
-
N. Fukushima, N. Sato, F. Sahin, G.H. Su, R.H. Hruban, and M. Goggins Aberrant methylation of suppressor of cytokine signalling-1 (SOCS-1) gene in pancreatic ductal neoplasms Br J Cancer 89 2003 338 343
-
(2003)
Br J Cancer
, vol.89
, pp. 338-343
-
-
Fukushima, N.1
Sato, N.2
Sahin, F.3
Su, G.H.4
Hruban, R.H.5
Goggins, M.6
-
84
-
-
0037227602
-
Hypermethylation associated with inactivation of the SOCS-1 gene, a JAK/STAT inhibitor, in human hepatoblastomas
-
H. Nagai, T. Naka, Y. Terada, T. Komazaki, A. Yabe, and E. Jin Hypermethylation associated with inactivation of the SOCS-1 gene, a JAK/STAT inhibitor, in human hepatoblastomas J Hum Genet 48 2003 65 69
-
(2003)
J Hum Genet
, vol.48
, pp. 65-69
-
-
Nagai, H.1
Naka, T.2
Terada, Y.3
Komazaki, T.4
Yabe, A.5
Jin, E.6
-
85
-
-
1542345461
-
Aberrant methylation of SOCS-1 was observed in younger colorectal cancer patients
-
S. Fujitake, K. Hibi, O. Okochi, Y. Kodera, K. Ito, and S. Akiyama Aberrant methylation of SOCS-1 was observed in younger colorectal cancer patients J Gastroenterol 39 2004 120 124
-
(2004)
J Gastroenterol
, vol.39
, pp. 120-124
-
-
Fujitake, S.1
Hibi, K.2
Okochi, O.3
Kodera, Y.4
Ito, K.5
Akiyama, S.6
-
86
-
-
3242749984
-
Promoter CpG methylation of tumor suppressor genes in colorectal cancer and its relationship to clinical features
-
S.Y. Lin, K.T. Yeh, W.T. Chen, H.C. Chen, S.T. Chen, and H.Y. Chiou Promoter CpG methylation of tumor suppressor genes in colorectal cancer and its relationship to clinical features Oncol Rep 11 2004 341 348
-
(2004)
Oncol Rep
, vol.11
, pp. 341-348
-
-
Lin, S.Y.1
Yeh, K.T.2
Chen, W.T.3
Chen, H.C.4
Chen, S.T.5
Chiou, H.Y.6
-
87
-
-
8644249909
-
Epigenetic inactivation of SOCS-1 by CpG island hypermethylation in human gastric carcinoma
-
Y. Oshimo, K. Kuraoka, H. Nakayama, Y. Kitadai, K. Yoshida, and K. Chayama Epigenetic inactivation of SOCS-1 by CpG island hypermethylation in human gastric carcinoma Int J Cancer 112 2004 1003 1009
-
(2004)
Int J Cancer
, vol.112
, pp. 1003-1009
-
-
Oshimo, Y.1
Kuraoka, K.2
Nakayama, H.3
Kitadai, Y.4
Yoshida, K.5
Chayama, K.6
-
88
-
-
7044230875
-
Differential hypermethylation of SOCS genes in ovarian and breast carcinomas
-
K.D. Sutherland, G.J. Lindeman, D.Y. Choong, S. Wittlin, L. Brentzell, and W. Phillips Differential hypermethylation of SOCS genes in ovarian and breast carcinomas Oncogene 23 2004 7726 7733
-
(2004)
Oncogene
, vol.23
, pp. 7726-7733
-
-
Sutherland, K.D.1
Lindeman, G.J.2
Choong, D.Y.3
Wittlin, S.4
Brentzell, L.5
Phillips, W.6
-
89
-
-
6944250441
-
Constitutional activation of IL-6-mediated JAK/STAT pathway through hypermethylation of SOCS-1 in human gastric cancer cell line
-
K.F. To, M.W. Chan, W.K. Leung, E.K. Ng, J. Yu, and A.H. Bai Constitutional activation of IL-6-mediated JAK/STAT pathway through hypermethylation of SOCS-1 in human gastric cancer cell line Br J Cancer 91 2004 1335 1341
-
(2004)
Br J Cancer
, vol.91
, pp. 1335-1341
-
-
To, K.F.1
Chan, M.W.2
Leung, W.K.3
Ng, E.K.4
Yu, J.5
Bai, A.H.6
-
90
-
-
0038546657
-
SOCS1 methylation in patients with newly diagnosed acute myeloid leukemia
-
C.Y. Chen, W. Tsay, J.L. Tang, H.L. Shen, S.W. Lin, and S.Y. Huang SOCS1 methylation in patients with newly diagnosed acute myeloid leukemia Genes Chromosomes Cancer 37 2003 300 305
-
(2003)
Genes Chromosomes Cancer
, vol.37
, pp. 300-305
-
-
Chen, C.Y.1
Tsay, W.2
Tang, J.L.3
Shen, H.L.4
Lin, S.W.5
Huang, S.Y.6
-
91
-
-
0038784365
-
SOCS-1, a negative regulator of cytokine signaling, is frequently silenced by methylation in multiple myeloma
-
O. Galm, H. Yoshikawa, M. Esteller, R. Osieka, and J.G. Herman SOCS-1, a negative regulator of cytokine signaling, is frequently silenced by methylation in multiple myeloma Blood 101 2003 2784 2788
-
(2003)
Blood
, vol.101
, pp. 2784-2788
-
-
Galm, O.1
Yoshikawa, H.2
Esteller, M.3
Osieka, R.4
Herman, J.G.5
-
92
-
-
0344530291
-
Epigenetic alteration of the SOCS1 gene in chronic myeloid leukaemia
-
T.C. Liu, S.F. Lin, J.G. Chang, M.Y. Yang, S.Y. Hung, and C.S. Chang Epigenetic alteration of the SOCS1 gene in chronic myeloid leukaemia Br J Haematol 123 2003 654 661
-
(2003)
Br J Haematol
, vol.123
, pp. 654-661
-
-
Liu, T.C.1
Lin, S.F.2
Chang, J.G.3
Yang, M.Y.4
Hung, S.Y.5
Chang, C.S.6
-
93
-
-
0346694510
-
Aberrant methylation in promoter-associated CpG islands of multiple genes in therapy-related leukemia
-
E. Uehara, S. Takeuchi, T. Tasaka, Y. Matsuhashi, Y. Yang, and M. Fujita Aberrant methylation in promoter-associated CpG islands of multiple genes in therapy-related leukemia Int J Oncol 23 2003 693 696
-
(2003)
Int J Oncol
, vol.23
, pp. 693-696
-
-
Uehara, E.1
Takeuchi, S.2
Tasaka, T.3
Matsuhashi, Y.4
Yang, Y.5
Fujita, M.6
-
94
-
-
7244237957
-
Aberrant methylation of multiple tumor suppressor genes in acute myeloid leukemia
-
C.G. Ekmekci, M.I. Gutierrez, A.K. Siraj, U. Ozbek, and K. Bhatia Aberrant methylation of multiple tumor suppressor genes in acute myeloid leukemia Am J Hematol 77 2004 233 240
-
(2004)
Am J Hematol
, vol.77
, pp. 233-240
-
-
Ekmekci, C.G.1
Gutierrez, M.I.2
Siraj, A.K.3
Ozbek, U.4
Bhatia, K.5
-
95
-
-
0031017533
-
Mutation in the Jak kinase JH2 domain hyperactivates Drosophila and mammalian Jak-Stat pathways
-
H. Luo, P. Rose, D. Barber, W.P. Hanratty, S. Lee, and T.M. Roberts Mutation in the Jak kinase JH2 domain hyperactivates Drosophila and mammalian Jak-Stat pathways Mol Cell Biol 17 1997 1562 1571
-
(1997)
Mol Cell Biol
, vol.17
, pp. 1562-1571
-
-
Luo, H.1
Rose, P.2
Barber, D.3
Hanratty, W.P.4
Lee, S.5
Roberts, T.M.6
-
96
-
-
4544358147
-
Suppressor of cytokine signalling-1 gene silencing in acute myeloid leukaemia and human haematopoietic cell lines
-
D. Watanabe, S. Ezoe, M. Fujimoto, A. Kimura, Y. Saito, and H. Nagai Suppressor of cytokine signalling-1 gene silencing in acute myeloid leukaemia and human haematopoietic cell lines Br J Haematol 126 2004 726 735
-
(2004)
Br J Haematol
, vol.126
, pp. 726-735
-
-
Watanabe, D.1
Ezoe, S.2
Fujimoto, M.3
Kimura, A.4
Saito, Y.5
Nagai, H.6
-
97
-
-
24944476696
-
Hypermethylation of the suppressor of cytokine signalling-1 (SOCS-1) in myelodysplastic syndrome
-
K. Brakensiek, F. Langer, B. Schlegelberger, H. Kreipe, and U. Lehmann Hypermethylation of the suppressor of cytokine signalling-1 (SOCS-1) in myelodysplastic syndrome Br J Haematol 130 2005 209 217
-
(2005)
Br J Haematol
, vol.130
, pp. 209-217
-
-
Brakensiek, K.1
Langer, F.2
Schlegelberger, B.3
Kreipe, H.4
Lehmann, U.5
-
98
-
-
27144433826
-
Methylation silencing of SOCS-3 promotes cell growth and migration by enhancing JAK/STAT and FAK signalings in human hepatocellular carcinoma
-
Y. Niwa, H. Kanda, Y. Shikauchi, A. Saiura, K. Matsubara, and T. Kitagawa Methylation silencing of SOCS-3 promotes cell growth and migration by enhancing JAK/STAT and FAK signalings in human hepatocellular carcinoma Oncogene 24 2005 6406 6417
-
(2005)
Oncogene
, vol.24
, pp. 6406-6417
-
-
Niwa, Y.1
Kanda, H.2
Shikauchi, Y.3
Saiura, A.4
Matsubara, K.5
Kitagawa, T.6
-
99
-
-
27144540201
-
SOCS-3 is frequently methylated in head and neck squamous cell carcinoma and its precursor lesions and causes growth inhibition
-
A. Weber, U.R. Hengge, W. Bardenheuer, I. Tischoff, F. Sommerer, and A. Markwarth SOCS-3 is frequently methylated in head and neck squamous cell carcinoma and its precursor lesions and causes growth inhibition Oncogene 24 2005 6699 6708
-
(2005)
Oncogene
, vol.24
, pp. 6699-6708
-
-
Weber, A.1
Hengge, U.R.2
Bardenheuer, W.3
Tischoff, I.4
Sommerer, F.5
Markwarth, A.6
-
100
-
-
3142510602
-
Constitutive STAT6 activation in primary mediastinal large B-cell lymphoma
-
C. Guiter, I. Dusanter-Fourt, C. Copie-Bergman, M.L. Boulland, S. Le Gouvello, and P. Gaulard Constitutive STAT6 activation in primary mediastinal large B-cell lymphoma Blood 104 2004 543 549
-
(2004)
Blood
, vol.104
, pp. 543-549
-
-
Guiter, C.1
Dusanter-Fourt, I.2
Copie-Bergman, C.3
Boulland, M.L.4
Le Gouvello, S.5
Gaulard, P.6
-
101
-
-
15244350510
-
Biallelic mutation of SOCS-1 impairs JAK2 degradation and sustains phospho-JAK2 action in the MedB-1 mediastinal lymphoma line
-
I. Melzner, A.J. Bucur, S. Bruderlein, K. Dorsch, C. Hasel, and T.F. Barth Biallelic mutation of SOCS-1 impairs JAK2 degradation and sustains phospho-JAK2 action in the MedB-1 mediastinal lymphoma line Blood 105 2005 2535 2542
-
(2005)
Blood
, vol.105
, pp. 2535-2542
-
-
Melzner, I.1
Bucur, A.J.2
Bruderlein, S.3
Dorsch, K.4
Hasel, C.5
Barth, T.F.6
-
102
-
-
32144453118
-
Biallelic deletion within 16p13.13 including SOCS-1 in Karpas1106P mediastinal B-cell lymphoma line is associated with delayed degradation of JAK2 protein
-
I. Melzner, M.A. Weniger, A.J. Bucur, S. Bruderlein, K. Dorsch, and C. Hasel Biallelic deletion within 16p13.13 including SOCS-1 in Karpas1106P mediastinal B-cell lymphoma line is associated with delayed degradation of JAK2 protein Int J Cancer 2005
-
(2005)
Int J Cancer
-
-
Melzner, I.1
Weniger, M.A.2
Bucur, A.J.3
Bruderlein, S.4
Dorsch, K.5
Hasel, C.6
-
103
-
-
0034653478
-
Transforming properties of chimeric TEL-JAK proteins in Ba/F3 cells
-
V. Lacronique, A. Boureux, R. Monni, S. Dumon, M. Mauchauffe, and P. Mayeux Transforming properties of chimeric TEL-JAK proteins in Ba/F3 cells Blood 95 2000 2076 2083
-
(2000)
Blood
, vol.95
, pp. 2076-2083
-
-
Lacronique, V.1
Boureux, A.2
Monni, R.3
Dumon, S.4
Mauchauffe, M.5
Mayeux, P.6
|