A rapamycin-sensitive pathway down-regulates insulin signaling via phosphorylation and proteasomal degradation of insulin receptor substrate-1

Molecular Endocrinology

Volumn 14, Issue 6, 2000, Pages 783-794

  Haruta, Tetsuro ^a   Uno, Tatsuhito ^a   Kawahara, Junko ^a   Takano, Atsuko ^a   Egawa, Katsuya ^b   Sharma, Prem M ^b   Olefsky, Jerrold M ^b,c   Kobayashi, Masashi ^a  

^a UNIVERSITY OF TOYAMA   (Japan)

^b UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^c VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INSULIN; INSULIN RECEPTOR; INSULIN RECEPTOR SUBSTRATE 1; LACTACYSTIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEASOME; PROTEIN KINASE; RAPAMYCIN;

ADIPOCYTE; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; INSULIN RELEASE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN PHOSPHORYLATION; VIRUS RECOMBINANT;

ADENOVIRIDAE; ANIMALIA;

EID: 0034463918     PISSN: 08888809     EISSN: None     Source Type: Journal    
DOI: 10.1210/mend.14.6.0446     Document Type: Article

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