Drosophila dFOXO controls lifespan and regulates insulin signalling in brain and fat body

Nature

Volumn 429, Issue 6991, 2004, Pages 562-566

  Hwangbo, Dae Sung ^a   Garsham, Boris ^a   Tu, Meng Ping ^a   Palmer, Michael ^a   Tatar, Marc ^a  

^a BROWN UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARBOHYDRATES; CELLS; GENETIC ENGINEERING; SUBSTRATES;

INSULIN LIKE RECEPTORS (INR); LIFE EXPECTANCY;

INSULIN;

DILP 2 PEPTIDE; HORMONE; INSULIN; INSULIN LIKE RECEPTOR; PEPTIDE; RECEPTOR; TRANSCRIPTION FACTOR FKHR; UNCLASSIFIED DRUG;

MEDICINE;

AGING; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BODY FAT; BRAIN; CAENORHABDITIS ELEGANS; CONTROLLED STUDY; DAF 16 GENE; DROSOPHILA MELANOGASTER; FEMALE; GENE; INSULIN SYNTHESIS; LIFE EXPECTANCY; LIFESPAN; MALE; MUTATION; NEMATODE; NERVE CELL; NONHUMAN; PEPTIDE SYNTHESIS; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION;

AGING; ANIMALS; BRAIN; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; FAT BODY; FORKHEAD TRANSCRIPTION FACTORS; GENES, INSECT; INSECT HORMONES; INSULIN; LONGEVITY; NEURONS; ORGAN SPECIFICITY; PHOSPHORIC MONOESTER HYDROLASES; PTEN PHOSPHOHYDROLASE; RECEPTOR, INSULIN; RNA, MESSENGER; SIGNAL TRANSDUCTION; STRESS; SURVIVAL RATE; TRANSCRIPTION FACTORS;

ANIMALIA; ARACHNIDA; CAENORHABDITIS; CAENORHABDITIS ELEGANS; DROSOPHILA MELANOGASTER; HEXAPODA; INSECTA; MAMMALIA; MELANOGASTER; NEMATODA;

EID: 2942563805     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/nature02549     Document Type: Article

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