메뉴 건너뛰기




Volumn 16, Issue 11, 1996, Pages 6242-6251

The principal rapamycin-sensitive p70(s6k) phosphorylation sites, T-229 and T-389, are differentially regulated by rapamycin-insensitive kinase kinases

Author keywords

[No Author keywords available]

Indexed keywords

RAPAMYCIN;

EID: 0029828590     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.16.11.6242     Document Type: Article
Times cited : (231)

References (51)
  • 1
    • 0026100595 scopus 로고
    • MAP2 kinase and 70 kDa S6 kinase lie on distinct signalling pathways
    • Ballou, L. M., H. Luther, and G. Thomas. 1991. MAP2 kinase and 70 kDa S6 kinase lie on distinct signalling pathways. Nature (London) 349:348-350.
    • (1991) Nature (London) , vol.349 , pp. 348-350
    • Ballou, L.M.1    Luther, H.2    Thomas, G.3
  • 2
    • 0027415831 scopus 로고
    • Identification of 40S ribosomal protein S6 phosphorylation sites in Swiss mouse 3T3 fibroblasts stimulated with serum
    • Bandi, H. R., S. Ferrari, J. Krieg, H. E. Meyer, and G. Thomas. 1993. Identification of 40S ribosomal protein S6 phosphorylation sites in Swiss mouse 3T3 fibroblasts stimulated with serum. J. Biol. Chem. 268:4530-4533.
    • (1993) J. Biol. Chem. , vol.268 , pp. 4530-4533
    • Bandi, H.R.1    Ferrari, S.2    Krieg, J.3    Meyer, H.E.4    Thomas, G.5
  • 5
    • 0028838845 scopus 로고
    • A target for phosphoinositide 3-kinase: Akt/PKB
    • Bos, J. L. 1995. A target for phosphoinositide 3-kinase: Akt/PKB. Trends Biochem. Sci. 20:441-442.
    • (1995) Trends Biochem. Sci. , vol.20 , pp. 441-442
    • Bos, J.L.1
  • 6
    • 0025998840 scopus 로고
    • Phosphopeptide mapping and phosphoamino acid analysis by two-dimensional separation on thin-layer cellulose plates
    • Boyle, W. J., P. van der Geer, and T. Hunter. 1991. Phosphopeptide mapping and phosphoamino acid analysis by two-dimensional separation on thin-layer cellulose plates. Methods Enzymol. 201:110-149.
    • (1991) Methods Enzymol. , vol.201 , pp. 110-149
    • Boyle, W.J.1    Van Der Geer, P.2    Hunter, T.3
  • 9
    • 0029160069 scopus 로고
    • Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction
    • Burgering, B. M. T., and P. J. Coffer. 1995. Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction. Nature (London) 376: 599-602.
    • (1995) Nature (London) , vol.376 , pp. 599-602
    • Burgering, B.M.T.1    Coffer, P.J.2
  • 10
    • 0028052255 scopus 로고
    • Anisomycin-activated protein kinases p45 and p55 but not mitogen-activated protein kinases ERK-1 and -2 are implicated in the induction of c-fos and c-jun
    • Cano, E., C. A. Hazzalin, and L. C. Mahadevan. 1994. Anisomycin-activated protein kinases p45 and p55 but not mitogen-activated protein kinases ERK-1 and -2 are implicated in the induction of c-fos and c-jun. Mol. Cell. Biol. 14:7352-7362.
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 7352-7362
    • Cano, E.1    Hazzalin, C.A.2    Mahadevan, L.C.3
  • 12
    • 0029890229 scopus 로고    scopus 로고
    • The 70 kDa S6 kinase complexes with and is activated by the Rho family G proteins cdc42 and rac1
    • Chou, M. M., and J. Blenis. 1996. The 70 kDa S6 kinase complexes with and is activated by the Rho family G proteins cdc42 and rac1. Cell 85:573-583.
    • (1996) Cell , vol.85 , pp. 573-583
    • Chou, M.M.1    Blenis, J.2
  • 14
    • 0026659046 scopus 로고
    • Rapamycin-FKBP specifically blocks growth-dependent activation of and signaling by the 70 kDa S6 protein kinases
    • Chung, J., C. J. Kuo, G. R. Crabtree, and J. Blenis. 1992. Rapamycin-FKBP specifically blocks growth-dependent activation of and signaling by the 70 kDa S6 protein kinases. Cell 69:1227-1236.
    • (1992) Cell , vol.69 , pp. 1227-1236
    • Chung, J.1    Kuo, C.J.2    Crabtree, G.R.3    Blenis, J.4
  • 16
    • 0028144846 scopus 로고
    • c-Fos transcriptional activity stimulated by H-Ras-activated protein kinase distinct from JNK and ERK
    • Deng, T., and M. Karin. 1994. c-Fos transcriptional activity stimulated by H-Ras-activated protein kinase distinct from JNK and ERK. Nature (London) 371:171-175.
    • (1994) Nature (London) , vol.371 , pp. 171-175
    • Deng, T.1    Karin, M.2
  • 17
    • 0028022798 scopus 로고
    • Regulating S6 kinase
    • Downward, J. 1994. Regulating S6 kinase. Nature (London) 371:378-379.
    • (1994) Nature (London) , vol.371 , pp. 378-379
    • Downward, J.1
  • 18
    • 0029127284 scopus 로고
    • A target for PI(3) kinase
    • Downward, J. 1995. A target for PI(3) kinase. Nature (London) 376:553-554.
    • (1995) Nature (London) , vol.376 , pp. 553-554
    • Downward, J.1
  • 23
    • 0026688510 scopus 로고
    • Substrate recognition determinants of the mitogen-activated 70 K S6 kinase from rat liver
    • Flotow, H., and G. Thomas. 1992. Substrate recognition determinants of the mitogen-activated 70 K S6 kinase from rat liver. J. Biol. Chem. 267:3074-3078.
    • (1992) J. Biol. Chem. , vol.267 , pp. 3074-3078
    • Flotow, H.1    Thomas, G.2
  • 24
    • 0029079275 scopus 로고
    • The protein kinase encoded by the Akt protooncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase
    • Franke, T. F., S. I. Yang, T. O. Chan, K. Datta, A. Kazlauskas, D. K. Morrison, D. R. Kaplan, and P. N. Tsichlis. 1995. The protein kinase encoded by the Akt protooncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase. Cell 81:727-736.
    • (1995) Cell , vol.81 , pp. 727-736
    • Franke, T.F.1    Yang, S.I.2    Chan, T.O.3    Datta, K.4    Kazlauskas, A.5    Morrison, D.K.6    Kaplan, D.R.7    Tsichlis, P.N.8
  • 26
    • 0002308879 scopus 로고
    • The eukaryotic protein kinase superfamily
    • G. Hardie and S. K. Hanks (ed.), Protein-serine kinases. Academic Press, London
    • Hanks, S. K., and T. Hunter. 1995. The eukaryotic protein kinase superfamily, p. 7-47. In G. Hardie and S. K. Hanks (ed.), The protein kinase facts book. Protein-serine kinases. Academic Press, London.
    • (1995) The Protein Kinase Facts Book , pp. 7-47
    • Hanks, S.K.1    Hunter, T.2
  • 28
    • 0028986738 scopus 로고
    • Normal activation of p70 S6 kinase by insulin in cells overexpressing dominant negative 85 kDa subunit of phosphoinositide 3-kinase
    • Hara, K., K. Yonezawa, H. Sakaue, K. Kotani, A. Kojima, M. D. Waterfield, and M. Kasuga. 1995. Normal activation of p70 S6 kinase by insulin in cells overexpressing dominant negative 85 kDa subunit of phosphoinositide 3-kinase. Biochem. Biophys. Res. Commun. 208:735-741.
    • (1995) Biochem. Biophys. Res. Commun. , vol.208 , pp. 735-741
    • Hara, K.1    Yonezawa, K.2    Sakaue, H.3    Kotani, K.4    Kojima, A.5    Waterfield, M.D.6    Kasuga, M.7
  • 29
    • 0027423418 scopus 로고
    • Identification of an oncoprotein- and UV-responsive protein kinase that binds and potentiates the c-jun activation domain
    • Hibi, M., A. Lin, T. Smeal, A. Minden, and M. Karin. 1993. Identification of an oncoprotein- and UV-responsive protein kinase that binds and potentiates the c-jun activation domain. Genes Dev. 7:2135-2148.
    • (1993) Genes Dev. , vol.7 , pp. 2135-2148
    • Hibi, M.1    Lin, A.2    Smeal, T.3    Minden, A.4    Karin, M.5
  • 30
    • 0028856331 scopus 로고
    • When is a lipid kinase not a lipid kinase? When it is a protein kinase
    • Hunter, T. 1995. When is a lipid kinase not a lipid kinase? When it is a protein kinase. Cell 83:1-4.
    • (1995) Cell , vol.83 , pp. 1-4
    • Hunter, T.1
  • 31
    • 0023656393 scopus 로고
    • Activation of a ribosomal protein S6 kinase in mouse fibroblasts during infection with herpesvirus
    • Jakubowicz, T., and D. P. Leader. 1987. Activation of a ribosomal protein S6 kinase in mouse fibroblasts during infection with herpesvirus. Eur. J. Biochem. 168:371-376.
    • (1987) Eur. J. Biochem. , vol.168 , pp. 371-376
    • Jakubowicz, T.1    Leader, D.P.2
  • 32
    • 0003018665 scopus 로고
    • Ribosomal protein S6 phosphorylation and signal transduction
    • J. W. B. Hershey, M. B. Mathews, and N. Sonenberg (ed.), Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
    • Jefferies, H. B. J., and G. Thomas. 1995. Ribosomal protein S6 phosphorylation and signal transduction. p. 389-410. In J. W. B. Hershey, M. B. Mathews, and N. Sonenberg (ed.), Translational control. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
    • (1995) Translational Control , pp. 389-410
    • Jefferies, H.B.J.1    Thomas, G.2
  • 33
    • 0024434183 scopus 로고
    • Autophosphorylation of the PDGF receptor in the kinase insert region regulates interactions with cell proteins
    • Kazlauskas, A., and J. A. Cooper. 1989. Autophosphorylation of the PDGF receptor in the kinase insert region regulates interactions with cell proteins. Cell 58:1121-1133.
    • (1989) Cell , vol.58 , pp. 1121-1133
    • Kazlauskas, A.1    Cooper, J.A.2
  • 34
    • 0027311858 scopus 로고
    • Target of rapamycin in yeast, TOR2 is an essential phosphatidylinositol kinase homologue required for G, progression
    • Kunz, J., R. Henriquez, U. Scheider, M. Deuter-Reinhard, N. R. Movva, and M. N. Hall. 1993. Target of rapamycin in yeast, TOR2 is an essential phosphatidylinositol kinase homologue required for G, progression. Cell 73:585-596.
    • (1993) Cell , vol.73 , pp. 585-596
    • Kunz, J.1    Henriquez, R.2    Scheider, U.3    Deuter-Reinhard, M.4    Movva, N.R.5    Hall, M.N.6
  • 36
    • 85035175464 scopus 로고    scopus 로고
    • Personal communication
    • 35a. Loreni, F. Personal communication.
    • Loreni, F.1
  • 37
    • 0029656153 scopus 로고    scopus 로고
    • Constitutive activation of S6 kinase by deletion of amino-terminal autoinhibitory and rapamycin sensitivity domains
    • Mahalingam, M., and D. J. Templeton. 1996. Constitutive activation of S6 kinase by deletion of amino-terminal autoinhibitory and rapamycin sensitivity domains. Mol. Cell. Biol. 16:405-413.
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 405-413
    • Mahalingam, M.1    Templeton, D.J.2
  • 38
    • 0000732112 scopus 로고    scopus 로고
    • Translational control of ribosomal protein mRNAs in eukaryotes
    • J. W. B. Hershey, M. B. Mathews, and N. Sonenberg (ed.), Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
    • Meyuhas, O., D. Avni, and S. Shama. 1996. Translational control of ribosomal protein mRNAs in eukaryotes, p. 363-388. In J. W. B. Hershey, M. B. Mathews, and N. Sonenberg (ed.), Translational control. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
    • (1996) Translational Control , pp. 363-388
    • Meyuhas, O.1    Avni, D.2    Shama, S.3
  • 40
    • 0026757270 scopus 로고
    • An array of insulin-activated, proline-directed serine/threonine protein kinases phosphorylate the p70 S6 kinase
    • Mukhopadhyay, N. K., D. J. Price, J. M. Kyriakis, S. L. Pelech, J. Sanghera, and J. Avruch. 1992. An array of insulin-activated, proline-directed serine/threonine protein kinases phosphorylate the p70 S6 kinase. J. Biol. Chem. 267:3325-3335.
    • (1992) J. Biol. Chem. , vol.267 , pp. 3325-3335
    • Mukhopadhyay, N.K.1    Price, D.J.2    Kyriakis, J.M.3    Pelech, S.L.4    Sanghera, J.5    Avruch, J.6
  • 41
  • 43
    • 0026759874 scopus 로고
    • Rapamycin-induced inhibition of the 70-kilodalton S6 protein kinase
    • Price, D. J., J. R. Grove, V. Calvo, J. Avruch, and B. E. Bierer. 1992. Rapamycin-induced inhibition of the 70-kilodalton S6 protein kinase. Science 257:973-977.
    • (1992) Science , vol.257 , pp. 973-977
    • Price, D.J.1    Grove, J.R.2    Calvo, V.3    Avruch, J.4    Bierer, B.E.5
  • 44
    • 0025948372 scopus 로고
    • Insulin-activated kinases phosphorylate a pseudo-substrate inhibitor of the p70 S6 kinase
    • Price, D. J., N. K. Mukhopadhyay, and J. Avruch. 1991. Insulin-activated kinases phosphorylate a pseudo-substrate inhibitor of the p70 S6 kinase. J. Biol. Chem. 266:16281-16284.
    • (1991) J. Biol. Chem. , vol.266 , pp. 16281-16284
    • Price, D.J.1    Mukhopadhyay, N.K.2    Avruch, J.3
  • 46
    • 0026504296 scopus 로고
    • A single gene encodes two isoforms of the p70 S6 kinase: Activation upon mitogenic stimulation
    • Reinhard, C., G. Thomas, and S. C. Kozma. 1992. A single gene encodes two isoforms of the p70 S6 kinase: activation upon mitogenic stimulation. Proc. Natl. Acad. Sci. USA 89:4052-4056.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 4052-4056
    • Reinhard, C.1    Thomas, G.2    Kozma, S.C.3
  • 47
    • 0028533984 scopus 로고
    • Mitogenesis and protein synthesis: A role for ribosomal protein S6 phosphorylation?
    • Stewart, M. J., and G. Thomas. 1994. Mitogenesis and protein synthesis: a role for ribosomal protein S6 phosphorylation? Bioessays 16:1-7.
    • (1994) Bioessays , vol.16 , pp. 1-7
    • Stewart, M.J.1    Thomas, G.2
  • 48
    • 0345718667 scopus 로고
    • Antibiotic inhibitors of translation in eukaryotes
    • G. Chambliss, G. R. Craven, J. Davis, K. Davis, L. Kahan, and M. Nomura (ed.), University Park Press, Baltimore
    • Vazquez, D., and A. Jimenez. 1980. Antibiotic inhibitors of translation in eukaryotes, p. 847-870. In G. Chambliss, G. R. Craven, J. Davis, K. Davis, L. Kahan, and M. Nomura (ed.), Ribosomes. Structure, function and genetics. University Park Press, Baltimore.
    • (1980) Ribosomes. Structure, Function and Genetics , pp. 847-870
    • Vazquez, D.1    Jimenez, A.2
  • 50
    • 0028999052 scopus 로고
    • Phosphatidylinositol 3-kinase signals activation of p70 S6 kinase in situ through site specific p70 phosphorylation
    • Weng, Q.-P., K. Andrabi, A. Klippel, M. T. Kozlowski, L. T. Williams, and J. Avruch. 1995. Phosphatidylinositol 3-kinase signals activation of p70 S6 kinase in situ through site specific p70 phosphorylation. Proc. Natl. Acad. Sci. USA 92:5744-5748.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 5744-5748
    • Weng, Q.-P.1    Andrabi, K.2    Klippel, A.3    Kozlowski, M.T.4    Williams, L.T.5    Avruch, J.6
  • 51
    • 0028939115 scopus 로고
    • Multiple independent inputs are required for activation of the p70 S6 kinase
    • Weng, Q.-P., K. Andrabi, M. T. Kozlowski, J. R. Grove, and J. Avruch. 1995 Multiple independent inputs are required for activation of the p70 S6 kinase. Mol. Cell. Biol. 15:2333-2340.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 2333-2340
    • Weng, Q.-P.1    Andrabi, K.2    Kozlowski, M.T.3    Grove, J.R.4    Avruch, J.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.