-
1
-
-
0030831210
-
A human homologue of the Drosophila Toll protein signals activation of adaptive immunity
-
Medzhitov R, Preston-Hurlburt P, Janeway CA Jr. A human homologue of the Drosophila Toll protein signals activation of adaptive immunity. Nature 1997; 388: 394-397
-
(1997)
Nature
, vol.388
, pp. 394-397
-
-
Medzhitov, R.1
Preston-Hurlburt, P.2
Janeway Jr., C.A.3
-
2
-
-
0034681434
-
Identification of two major sites in the type I interleukin-1 receptor cytoplasmic region responsible for coupling to pro-inflammatory signaling pathways
-
Slack JL, Schooley K, Bonnert TP, Mitcham JL, Qwarnstrom EE, Sims JE, et al. Identification of two major sites in the type I interleukin-1 receptor cytoplasmic region responsible for coupling to pro-inflammatory signaling pathways. J Biol Chem 2000; 275: 4670-4678
-
(2000)
J Biol Chem
, vol.275
, pp. 4670-4678
-
-
Slack, J.L.1
Schooley, K.2
Bonnert, T.P.3
Mitcham, J.L.4
Qwarnstrom, E.E.5
Sims, J.E.6
-
3
-
-
29244450802
-
Intracellular localization of Toll-like receptor 9 prevents recognition of self-DNA but facilitates access to viral DNA
-
Barton GM, Kagan JC, Medzhitov R. Intracellular localization of Toll-like receptor 9 prevents recognition of self-DNA but facilitates access to viral DNA. Nat Immunol 2006; 7: 49-56.
-
(2006)
Nat Immunol
, vol.7
, pp. 49-56
-
-
Barton, G.M.1
Kagan, J.C.2
Medzhitov, R.3
-
4
-
-
33645111302
-
The transmembrane domain directs TLR9 to intracellular compartments that contain TLR3
-
Kajita E, Nishiya T, Miwa S. The transmembrane domain directs TLR9 to intracellular compartments that contain TLR3. Biochem Biophys Res Comun 2006; 343: 578-584
-
(2006)
Biochem Biophys Res Comun
, vol.343
, pp. 578-584
-
-
Kajita, E.1
Nishiya, T.2
Miwa, S.3
-
5
-
-
41349112917
-
Cytosolic DNA recognition for triggering innate immune responses
-
Takaoka A, Taniguchi T. Cytosolic DNA recognition for triggering innate immune responses. Adv Drug Deliv Rev 2008; 60: 847-857
-
(2008)
Adv Drug Deliv Rev
, vol.60
, pp. 847-857
-
-
Takaoka, A.1
Taniguchi, T.2
-
6
-
-
58049220365
-
Pattern recognition receptors and control of adaptive immunity
-
Palm NW, Medzhitov R. Pattern recognition receptors and control of adaptive immunity. Immunol Rev 2009; 227: 221-233
-
(2009)
Immunol Rev
, vol.227
, pp. 221-233
-
-
Palm, N.W.1
Medzhitov, R.2
-
7
-
-
65649123377
-
Toll-Like Receptors and their Role in Hematologic Malignancies
-
Wolska A, Lech-Maranda E, Robak T. Toll-Like Receptors and their Role in Hematologic Malignancies. Curr Mol Med 2009; 9: 324-335
-
(2009)
Curr Mol Med
, vol.9
, pp. 324-335
-
-
Wolska, A.1
Lech-Maranda, E.2
Robak, T.3
-
8
-
-
59349116736
-
Toll-like receptor signaling in endogenous neuroprotection and stroke
-
Marsh BJ, Williams-Karnesky RL, Stenzel-Poore MP. Toll-like receptor signaling in endogenous neuroprotection and stroke. Neuroscience 2009; 158: 1007-1020
-
(2009)
Neuroscience
, vol.158
, pp. 1007-1020
-
-
Marsh, B.J.1
Williams-Karnesky, R.L.2
Stenzel-Poore, M.P.3
-
9
-
-
65649108429
-
The critical role of toll-like receptor signaling pathways in the induction and progression of autoimmune diseases
-
Li M, Zhou Y, Feng G, Su SB. The critical role of toll-like receptor signaling pathways in the induction and progression of autoimmune diseases. Curr Mol Med 2009; 9: 365-374
-
(2009)
Curr Mol Med
, vol.9
, pp. 365-374
-
-
Li, M.1
Zhou, Y.2
Feng, G.3
Su, S.B.4
-
10
-
-
16244376480
-
Toll-like receptors, endogenous ligands, and systemic autoimmune disease
-
Rifkin IR, Leadbetter EA, Busconi L, Viglianti G, Marshak-Rothstein A. Toll-like receptors, endogenous ligands, and systemic autoimmune disease. Immunol Rev 2005; 204: 27-42.
-
(2005)
Immunol Rev
, vol.204
, pp. 27-42
-
-
Rifkin, I.R.1
Leadbetter, E.A.2
Busconi, L.3
Viglianti, G.4
Marshak-Rothstein, A.5
-
11
-
-
32944464648
-
Pathogen recognition and innate immunity
-
Akira S, Uematsu S, Takeuchi O. Pathogen recognition and innate immunity. Cell 2006; 124: 783-801.
-
(2006)
Cell
, vol.124
, pp. 783-801
-
-
Akira, S.1
Uematsu, S.2
Takeuchi, O.3
-
12
-
-
75449093273
-
TIR-containing adaptors in Toll-like receptor signalling
-
March 3; doi:10.1016/j.cyto.2009.01.009
-
Jenkins KA, Mansell A. TIR-containing adaptors in Toll-like receptor signalling. Cytoquine 2009; March 3; doi:10.1016/j.cyto.2009.01.009.
-
(2009)
Cytoquine
-
-
Jenkins, K.A.1
Mansell, A.2
-
13
-
-
51349158231
-
Signalling adaptors used by Toll-like receptors: An update
-
Kenny EF, O'Neill LAJ. Signalling adaptors used by Toll-like receptors: an update. Cytokine 2008; 43: 342-349
-
(2008)
Cytokine
, vol.43
, pp. 342-349
-
-
Kenny, E.F.1
O'Neill, L.A.J.2
-
14
-
-
33748871187
-
The human adaptor SARM negatively regulates adaptor protein TRIF-dependent Toll-like receptor signaling
-
Carty M, Goodbody R, Schröder M, Stack J, Moynagh PN, Bowie AG. The human adaptor SARM negatively regulates adaptor protein TRIF-dependent Toll-like receptor signaling. Nat Immunol 2006; 7: 1074-1081
-
(2006)
Nat Immunol
, vol.7
, pp. 1074-1081
-
-
Carty, M.1
Goodbody, R.2
Schröder, M.3
Stack, J.4
Moynagh, P.N.5
Bowie, A.G.6
-
18
-
-
56549116047
-
Toll-like receptor and RIG-I-like receptor signaling
-
Kawai T, Akira S. Toll-like receptor and RIG-I-like receptor signaling. Ann NY Acad Sci 2008; 1143: 1-20.
-
(2008)
Ann NY Acad Sci
, vol.1143
, pp. 1-20
-
-
Kawai, T.1
Akira, S.2
-
19
-
-
44049097129
-
Sequential control of Toll-like receptor-dependent responses by IRAK1 and IRAK2
-
Kawagoe T, Sato S, Matsushita K, Kato H, Matsui K, Kumagai Y, et al. Sequential control of Toll-like receptor-dependent responses by IRAK1 and IRAK2. Nat Immunol 2008; 9: 684-691
-
(2008)
Nat Immunol
, vol.9
, pp. 684-691
-
-
Kawagoe, T.1
Sato, S.2
Matsushita, K.3
Kato, H.4
Matsui, K.5
Kumagai, Y.6
-
20
-
-
67449092565
-
Interleukin-1 receptor-associated kinase 2 is critical for lipopolysaccharide-mediated post-transcriptional control
-
Wan Y, Xiao H, Affolter J, Kim TW, Bulek K, Chaudhuri S, et al. Interleukin-1 receptor-associated kinase 2 is critical for lipopolysaccharide- mediated post-transcriptional control. J Biol Chem 2009; 284: 10367-10375
-
(2009)
J Biol Chem
, vol.284
, pp. 10367-10375
-
-
Wan, Y.1
Xiao, H.2
Affolter, J.3
Kim, T.W.4
Bulek, K.5
Chaudhuri, S.6
-
21
-
-
0037178785
-
IRAK-M is a negative regulator of Tolllike receptor signaling
-
Kobayashi K, Hernandez LD, Galán JE, Janeway CA, Jr, Medzhitov R, Flavell RA. IRAK-M is a negative regulator of Tolllike receptor signaling. Cell 2002; 110: 191-202.
-
(2002)
Cell
, vol.110
, pp. 191-202
-
-
Kobayashi, K.1
Hernandez, L.D.2
Galán, J.E.3
Janeway Jr., C.A.4
Medzhitov, R.5
Flavell, R.A.6
-
22
-
-
23144449789
-
Ubiquitin signalling in the NF-κB pathway
-
Chen ZJ. Ubiquitin signalling in the NF-κB pathway. Nat Cell Biol 2005; 7: 758-765
-
(2005)
Nat Cell Biol
, vol.7
, pp. 758-765
-
-
Chen, Z.J.1
-
23
-
-
67649382173
-
NESCA: A new NEMO/IKKgamma and TRAF6 interacting protein
-
doi. 10.1002/jcp.21782
-
Napolitano G, Mirra S, Monfregola J, Lavorgna A, Leonardi A, Ursini MV. NESCA: a new NEMO/IKKgamma and TRAF6 interacting protein. J Cell Physiol 2009; doi. 10.1002/jcp.21782.
-
(2009)
J Cell Physiol
-
-
Napolitano, G.1
Mirra, S.2
Monfregola, J.3
Lavorgna, A.4
Leonardi, A.5
Ursini, M.V.6
-
24
-
-
46749136412
-
When signaling pathways collide: Positive and negative regulation of toll-like receptor signal transduction
-
O'Neill LA. When signaling pathways collide: positive and negative regulation of toll-like receptor signal transduction. Immunity 2008; 29: 12-20.
-
(2008)
Immunity
, vol.29
, pp. 12-20
-
-
O'Neill, L.A.1
-
25
-
-
77950274021
-
Protein kinase D1 is essential for MyD88-dependent TLR signaling pathway
-
Park JE, Kim YI, Yi AK. Protein kinase D1 is essential for MyD88-dependent TLR signaling pathway. J Immunol 2009; 182: 6316-6327
-
(2009)
J Immunol
, vol.182
, pp. 6316-6327
-
-
Park, J.E.1
Kim, Y.I.2
Yi, A.K.3
-
26
-
-
39549116503
-
PI3K is critical for the nuclear translocation of IRF-7 and type I IFN production by human plasmacytoid predendritic cells in response to TLR activation
-
Guiducci C, Ghirelli C, Marloie-Provost MA, Matray T, Coffman RL, Liu YJ, et al. PI3K is critical for the nuclear translocation of IRF-7 and type I IFN production by human plasmacytoid predendritic cells in response to TLR activation. J Exp Med 2008; 205: 315-322
-
(2008)
J Exp Med
, vol.205
, pp. 315-322
-
-
Guiducci, C.1
Ghirelli, C.2
Marloie-Provost, M.A.3
Matray, T.4
Coffman, R.L.5
Liu, Y.J.6
-
27
-
-
45549096989
-
Turning NF-κB and IRFs on and off in DC
-
Kaisho T, Tanaka T. Turning NF-κB and IRFs on and off in DC. Trends Immunol 2008; 29: 329-336
-
(2008)
Trends Immunol
, vol.29
, pp. 329-336
-
-
Kaisho, T.1
Tanaka, T.2
-
28
-
-
30544451546
-
Specificity in Toll-like receptor signalling through distinct effector functions of TRAF3 and TRAF6
-
Häcker H, Redecke V, Blagoev B, Kratchmarova I, Hsu LC, Wang GG, et al. Specificity in Toll-like receptor signalling through distinct effector functions of TRAF3 and TRAF6. Nature 2006; 439: 204-207
-
(2006)
Nature
, vol.439
, pp. 204-207
-
-
Häcker, H.1
Redecke, V.2
Blagoev, B.3
Kratchmarova, I.4
Hsu, L.C.5
Wang, G.G.6
-
29
-
-
30544447047
-
Critical role of TRAF3 in the Toll-like receptor-dependent and -independent antiviral response
-
Oganesyan G, Saha SK, Guo B, He JQ, Shahangian A, Zarnegar B, et al. Critical role of TRAF3 in the Toll-like receptor-dependent and -independent antiviral response. Nature 2006; 439: 208-211
-
(2006)
Nature
, vol.439
, pp. 208-211
-
-
Oganesyan, G.1
Saha, S.K.2
Guo, B.3
He, J.Q.4
Shahangian, A.5
Zarnegar, B.6
-
30
-
-
33748051738
-
IRFs: Master regulators of signalling by Toll-like receptors and cytosolic pattern-recognition receptors
-
Honda K, Taniguchi T. IRFs: master regulators of signalling by Toll-like receptors and cytosolic pattern-recognition receptors. Nat Rev Immunol 2006; 6: 644-658
-
(2006)
Nat Rev Immunol
, vol.6
, pp. 644-658
-
-
Honda, K.1
Taniguchi, T.2
-
31
-
-
34548844720
-
Toll-like receptor signal transduction
-
Krishnan J, Selvarajoo K, Tsuchiya M, Lee G, Choi S. Toll-like receptor signal transduction. Exp Mol Med 2007; 39: 421-438
-
(2007)
Exp Mol Med
, vol.39
, pp. 421-438
-
-
Krishnan, J.1
Selvarajoo, K.2
Tsuchiya, M.3
Lee, G.4
Choi, S.5
-
32
-
-
58049193003
-
Microbe sensing, positive feedback loops, and the pathogenesis of inflammatory diseases
-
Beutler B. Microbe sensing, positive feedback loops, and the pathogenesis of inflammatory diseases. Immunol Rev 2009; 227: 248-263
-
(2009)
Immunol Rev
, vol.227
, pp. 248-263
-
-
Beutler, B.1
-
33
-
-
58049209834
-
Inflammatory signals in dendritic cell activation and the induction of adaptive immunity
-
Joffre O, Notle MA, Spörri R, Reis e Sousa C. Inflammatory signals in dendritic cell activation and the induction of adaptive immunity. Immunol Rev 2009; 227: 234-247
-
(2009)
Immunol Rev
, vol.227
, pp. 234-247
-
-
Joffre, O.1
Notle, M.A.2
Spörri, R.3
Reis E Sousa, C.4
-
34
-
-
58049206826
-
Crosstalk between components of innate immune system: Promoting anti-microbial defenses and avoiding immunopathologies
-
Crozat K, Vivier E, Dalod M. Crosstalk between components of innate immune system: promoting anti-microbial defenses and avoiding immunopathologies. Immunol Rev 2009; 227: 129-149
-
(2009)
Immunol Rev
, vol.227
, pp. 129-149
-
-
Crozat, K.1
Vivier, E.2
Dalod, M.3
-
35
-
-
58549089483
-
Toll-like receptors, wound healing and carcinogenesis
-
Kluwe J, Mencin A, Schawabe RF. Toll-like receptors, wound healing and carcinogenesis. J Mol Med 2009; 87: 125-138
-
(2009)
J Mol Med
, vol.87
, pp. 125-138
-
-
Kluwe, J.1
Mencin, A.2
Schawabe, R.F.3
-
36
-
-
32944474237
-
Innate Immunity gone awry: Linking microbial infections to chronic inflammation and cancer
-
Karin M, Lawrence T, Nizet V.Innate Immunity gone awry: linking microbial infections to chronic inflammation and cancer. Cell 2006; 124: 823-835
-
(2006)
Cell
, vol.124
, pp. 823-835
-
-
Karin, M.1
Lawrence, T.2
Nizet, V.3
-
38
-
-
58149269348
-
Carcinoma-produced factors activate myeloid cells through TLR2 to stimulate metastasis
-
Kim S, Takashi H, Lin WW, Descargues P, Grivennikov S, Kim Y, et al. Carcinoma-produced factors activate myeloid cells through TLR2 to stimulate metastasis. Nature 2009; 457: 102-107
-
(2009)
Nature
, vol.457
, pp. 102-107
-
-
Kim, S.1
Takashi, H.2
Lin, W.W.3
Descargues, P.4
Grivennikov, S.5
Kim, Y.6
-
39
-
-
33747114270
-
Role of toll-like receptors in spontaneous commensal-dependent colitis
-
Rakoff-Nahoum S, Hao L, Medzhitov R. Role of toll-like receptors in spontaneous commensal-dependent colitis. Immunity 2006; 25: 189-191
-
(2006)
Immunity
, vol.25
, pp. 189-191
-
-
Rakoff-Nahoum, S.1
Hao, L.2
Medzhitov, R.3
-
40
-
-
66349110620
-
Toll-like receptors as targets in chronic liver disease
-
Mencin A, Kluwe J, Schwabe RF. Toll-like receptors as targets in chronic liver disease. Gut 2009; 58: 704-720
-
(2009)
Gut
, vol.58
, pp. 704-720
-
-
Mencin, A.1
Kluwe, J.2
Schwabe, R.F.3
-
41
-
-
33846213140
-
Translational mini-review series on toll-like receptors: Toll-like receptors ligand as novel pharmaceuticals for allergic disorders
-
Goldman M. Translational mini-review series on toll-like receptors: toll-like receptors ligand as novel pharmaceuticals for allergic disorders. Clin Exp Immunol 2007; 147: 208-216
-
(2007)
Clin Exp Immunol
, vol.147
, pp. 208-216
-
-
Goldman, M.1
-
42
-
-
33846208784
-
Age associated defect in human TLR1/2 function
-
Van Duin D, Mohanty S, Thomas V, Ginter S, Montgomery RR, Fikrig E, et al. Age associated defect in human TLR1/2 function. J Immunol 2007; 178: 970-975
-
(2007)
J Immunol
, vol.178
, pp. 970-975
-
-
Van Duin, D.1
Mohanty, S.2
Thomas, V.3
Ginter, S.4
Montgomery, R.R.5
Fikrig, E.6
-
43
-
-
0032509295
-
Defective LPS signalling in C3H/HeJ and C57BL/10ScCr mice: Mutations in Tlr4 gene
-
Poltorak A, He X, Smirnova I, Liu MY, Van Fuel C, Due X, et al. Defective LPS signalling in C3H/HeJ and C57BL/10ScCr mice: mutations in Tlr4 gene. Science 1998; 282: 2085-2088
-
(1998)
Science
, vol.282
, pp. 2085-2088
-
-
Poltorak, A.1
He, X.2
Smirnova, I.3
Liu, M.Y.4
Van Fuel, C.5
Due, X.6
-
44
-
-
0037071251
-
Relevance of mutations in the TLR4 receptor in patients with gram-negative septic shock
-
Lorenz E, Mira JP, Frees KL, Scwartz DA. Relevance of mutations in the TLR4 receptor in patients with gram-negative septic shock. Arch Intern Med 2002; 162: 1028-1032
-
(2002)
Arch Intern Med
, vol.162
, pp. 1028-1032
-
-
Lorenz, E.1
Mira, J.P.2
Frees, K.L.3
Scwartz, D.A.4
-
45
-
-
0142031430
-
Role of Toll-like receptors in pathogen recognition
-
Janssen S, Beyaert R. Role of Toll-like receptors in pathogen recognition. Clin Microbiol Rev 2003; 16: 637-646
-
(2003)
Clin Microbiol Rev
, vol.16
, pp. 637-646
-
-
Janssen, S.1
Beyaert, R.2
-
46
-
-
4043115490
-
The potential of Toll-Like receptors to collaborate with other innate immune receptors
-
Mukhopadhyay S, Herre J, Brown GD, Gordon S. The potential of Toll-Like receptors to collaborate with other innate immune receptors. Immunology 2004; 112: 521-530
-
(2004)
Immunology
, vol.112
, pp. 521-530
-
-
Mukhopadhyay, S.1
Herre, J.2
Brown, G.D.3
Gordon, S.4
-
47
-
-
33846246749
-
Translation mini-review series on toll-like receptors. Recent advances in understanding the role of toll-like receptors in anti-viral immunity
-
Bowie AG. Translation mini-review series on toll-like receptors. Recent advances in understanding the role of toll-like receptors in anti-viral immunity. Clin Exp Immunol 2007; 147: 217-226
-
(2007)
Clin Exp Immunol
, vol.147
, pp. 217-226
-
-
Bowie, A.G.1
-
48
-
-
0043198258
-
Novel therapeutic strategies based on toll-like receptor signalling
-
Lawton JA, Ghosh P. Novel therapeutic strategies based on toll-like receptor signalling. Curr Opin Chem Biol 2003; 7: 446-451
-
(2003)
Curr Opin Chem Biol
, vol.7
, pp. 446-451
-
-
Lawton, J.A.1
Ghosh, P.2
-
49
-
-
34547851581
-
Toll-like receptors, new horizons in sepsis
-
Saturnino SF, Andrade MV. Toll-like receptors, new horizons in sepsis. Curr Mol Med 2007; 7: 522-531
-
(2007)
Curr Mol Med
, vol.7
, pp. 522-531
-
-
Saturnino, S.F.1
Andrade, M.V.2
-
50
-
-
11144273976
-
Toll-like receptor 3 mediates West Nile virus entry into the brain causing lethal encephalitis
-
Wang T, Town T, Alexopoulou L, Anderson JF, Fikrig E, Flavell RA. Toll-like receptor 3 mediates West Nile virus entry into the brain causing lethal encephalitis. Nat med 2004; 10: 1366-1373
-
(2004)
Nat Med
, vol.10
, pp. 1366-1373
-
-
Wang, T.1
Town, T.2
Alexopoulou, L.3
Anderson, J.F.4
Fikrig, E.5
Flavell, R.A.6
-
51
-
-
19944430901
-
Toll-receptor 9 mediates innate immune activation by the malaria pigment hemozoin
-
Coban C, Ishii KJ, Kawai T, Hemmi H, Sato S, Uematsu S, et al. Toll-receptor 9 mediates innate immune activation by the malaria pigment hemozoin. J Exp Med 2005; 201: 19-25.
-
(2005)
J Exp Med
, vol.201
, pp. 19-25
-
-
Coban, C.1
Ishii, K.J.2
Kawai, T.3
Hemmi, H.4
Sato, S.5
Uematsu, S.6
-
52
-
-
35349024974
-
Evidence for association between a toll-like receptor 4 gene polymorphism and moderate/severe periodontitis in the Japanese populatios
-
Fukusaki T, Ohara N, Hara Y, Yoshimura A, Yoshiura K. Evidence for association between a toll-like receptor 4 gene polymorphism and moderate/severe periodontitis in the Japanese populatios. J Peridontal Res 2007; 42: 541-545
-
(2007)
J Peridontal Res
, vol.42
, pp. 541-545
-
-
Fukusaki, T.1
Ohara, N.2
Hara, Y.3
Yoshimura, A.4
Yoshiura, K.5
-
53
-
-
1542409922
-
Toll-like receptor 2 suppresses immunity against Candida albicans through induction of IL-10 and regulatory T cells
-
Netea MG, Sutmuller R, Hermann C, Van der Graaf CA, Van der Meer JW, van Krieken JH. Toll-like receptor 2 suppresses immunity against Candida albicans through induction of IL-10 and regulatory T cells. J Immunol 2004; 172: 3712-3718
-
(2004)
J Immunol
, vol.172
, pp. 3712-3718
-
-
Netea, M.G.1
Sutmuller, R.2
Hermann, C.3
Van Der Graaf, C.A.4
Van Der Meer, J.W.5
Van Krieken, J.H.6
-
54
-
-
29744452892
-
Toll-like receptors in ocular immunity and the immunopathogenesis of inflammatory eye disease
-
Chang JH, McCluskey PJ, Wakefield D. Toll-like receptors in ocular immunity and the immunopathogenesis of inflammatory eye disease. Br J Ophthalmol 2006; 90: 103-108
-
(2006)
Br J Ophthalmol
, vol.90
, pp. 103-108
-
-
Chang, J.H.1
McCluskey, P.J.2
Wakefield, D.3
-
56
-
-
1542377424
-
A toll-like receptor prevents infection by uropathogenic bacteria
-
Zhang D, Zhang G, Hayden MS, Greenblatt MB, Bussey C, Flavel RA, et al. A toll-like receptor prevents infection by uropathogenic bacteria. Science 2004; 303: 1522-1526
-
(2004)
Science
, vol.303
, pp. 1522-1526
-
-
Zhang, D.1
Zhang, G.2
Hayden, M.S.3
Greenblatt, M.B.4
Bussey, C.5
Flavel, R.A.6
-
57
-
-
33646025516
-
Toll-like receptor 9 signaling for therapeutic use
-
Bhattacharjee RN, Akira S. Toll-like receptor 9 signaling for therapeutic use. Mini Rev Med Chem 2006; 6: 287-291
-
(2006)
Mini Rev Med Chem
, vol.6
, pp. 287-291
-
-
Bhattacharjee, R.N.1
Akira, S.2
-
58
-
-
1542721504
-
Toll-like receptor 2 as a major gene for asthma in children of European farmers
-
Eder W, Klimecki W, Yu L, von Mutius E, Riedler J, Braun-Fahrländer C, et al. Toll-like receptor 2 as a major gene for asthma in children of European farmers. J Allergy Clin Immunol 2004; 113: 482-488
-
(2004)
J Allergy Clin Immunol
, vol.113
, pp. 482-488
-
-
Eder, W.1
Klimecki, W.2
Yu, L.3
Von Mutius, E.4
Riedler, J.5
Braun-Fahrländer, C.6
-
59
-
-
4344688090
-
Toll-like receptor 6 gene (TLR6): Single-nucleotide polymorphism frequencies and preliminary association with the diagnosis of asthma
-
Tantisira K, Klimecki WT, Lazarus R, Palmer LJ, Raby BA, Kwiatkowski DJ, et al. Toll-like receptor 6 gene (TLR6): single-nucleotide polymorphism frequencies and preliminary association with the diagnosis of asthma. Genes Immun 2004; 5: 343-346
-
(2004)
Genes Immun
, vol.5
, pp. 343-346
-
-
Tantisira, K.1
Klimecki, W.T.2
Lazarus, R.3
Palmer, L.J.4
Raby, B.A.5
Kwiatkowski, D.J.6
-
60
-
-
34548448134
-
The contribution of Toll-like receptors to the pathogenesis of asthma
-
Phipps S, Lam CE, Foster PS, Matthaei KI. The contribution of Toll-like receptors to the pathogenesis of asthma. Immunol Cell Biol 2007; 85: 463-470
-
(2007)
Immunol Cell Biol
, vol.85
, pp. 463-470
-
-
Phipps, S.1
Lam, C.E.2
Foster, P.S.3
Matthaei, K.I.4
-
61
-
-
11844276029
-
Lipoprotein, a TLR2/4 ligand modulates Th2-driven allergic immune responses
-
Revets H, Pynaert G, Grooten J, De Baetselier P. Lipoprotein, a TLR2/4 ligand modulates Th2-driven allergic immune responses. J Immunol 2005; 174: 1097-1103
-
(2005)
J Immunol
, vol.174
, pp. 1097-1103
-
-
Revets, H.1
Pynaert, G.2
Grooten, J.3
De Baetselier, P.4
-
62
-
-
26444608592
-
Evaluation of the Toll-like receptor 6 Ser249Pro polymorphism in patients with asthma, atopic dermatitis and chronic obstructive pulmonary disease
-
Hoffjan S, Stemmler S, Parwez Q, Petrasch-Parwez E, Arinir U, Rohde G, et al. Evaluation of the Toll-like receptor 6 Ser249Pro polymorphism in patients with asthma, atopic dermatitis and chronic obstructive pulmonary disease. BMC Med Genet 2005; 6: 34.
-
(2005)
BMC Med Genet
, vol.6
, pp. 34
-
-
Hoffjan, S.1
Stemmler, S.2
Parwez, Q.3
Petrasch-Parwez, E.4
Arinir, U.5
Rohde, G.6
-
63
-
-
4444279410
-
Toll-like receptor 10 genetic variation in association with asthma in two independent samples
-
Lazarus R, Raby BA, Lange C, Silverman EK, Kwiatkowski DJ, Vercelli D, et al. Toll-like receptor 10 genetic variation in association with asthma in two independent samples. Am J Respir Crit Care Med 2004; 170: 594-600.
-
(2004)
Am J Respir Crit Care Med
, vol.170
, pp. 594-600
-
-
Lazarus, R.1
Raby, B.A.2
Lange, C.3
Silverman, E.K.4
Kwiatkowski, D.J.5
Vercelli, D.6
-
64
-
-
43049083361
-
Cell, mediators and toll-like receptors in COPD
-
Sarir H, Henricks PA, van Houwelingen AH, Nijkamp FP, Folerts G. Cell, mediators and toll-like receptors in COPD. Eur J Pharmacol 2008; 585: 346-353
-
(2008)
Eur J Pharmacol
, vol.585
, pp. 346-353
-
-
Sarir, H.1
Henricks, P.A.2
Van Houwelingen, A.H.3
Nijkamp, F.P.4
Folerts, G.5
-
65
-
-
33244495503
-
Multiple toll-like receptor agnist acts as potent adjuvants in the induction of autoimmunity
-
Hansen BS, Hussain RZ, Lovett-Racke AE, Thomas JA, Racke MK. Multiple toll-like receptor agnist acts as potent adjuvants in the induction of autoimmunity. J Neuroimmunol 2006; 172: 1256-1265
-
(2006)
J Neuroimmunol
, vol.172
, pp. 1256-1265
-
-
Hansen, B.S.1
Hussain, R.Z.2
Lovett-Racke, A.E.3
Thomas, J.A.4
Racke, M.K.5
-
66
-
-
42249109064
-
Unexpected regulatory roles of TLR4 and TLR9 in experimental autoimmune encephalomyelitis
-
Marta M, Andersson A, Isaksson M, Kümpe O, Lobell A. Unexpected regulatory roles of TLR4 and TLR9 in experimental autoimmune encephalomyelitis. Eur J Immunol 2008; 38: 565-575
-
(2008)
Eur J Immunol
, vol.38
, pp. 565-575
-
-
Marta, M.1
Andersson, A.2
Isaksson, M.3
Kümpe, O.4
Lobell, A.5
-
67
-
-
32444443739
-
Innate immunity mediated by TLR9 modulated pathogenicity in an animal model of multiple sclerosis
-
Prinz M, Garbe F, Schmidt H, Mildner A, Gutcher I, Wolter K, et al. Innate immunity mediated by TLR9 modulated pathogenicity in an animal model of multiple sclerosis. J Clin Invest 2006; 116: 456-464
-
(2006)
J Clin Invest
, vol.116
, pp. 456-464
-
-
Prinz, M.1
Garbe, F.2
Schmidt, H.3
Mildner, A.4
Gutcher, I.5
Wolter, K.6
-
68
-
-
46049120813
-
Toll-like receptors, transduction-effector pathways, and disease diversity: Evidence of an immunobiological paradigm explaining all human illness
-
Atkinson TJ. Toll-like receptors, transduction-effector pathways, and disease diversity: evidence of an immunobiological paradigm explaining all human illness. Int Rev Immunol 2008; 27: 255-281.
-
(2008)
Int Rev Immunol
, vol.27
, pp. 255-281
-
-
Atkinson, T.J.1
-
69
-
-
23044475966
-
A stop codon polymorphism of toll-like receptor 5 is associated with resistance to systemic lupus erythromatosus
-
Hawn TR, Wu H, Grossman JM, Hahn BH, Tsao BP, Aderem A. A stop codon polymorphism of toll-like receptor 5 is associated with resistance to systemic lupus erythromatosus. Proc Natl Acad Sci USA 2005; 102: 10593-10597
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 10593-10597
-
-
Hawn, T.R.1
Wu, H.2
Grossman, J.M.3
Hahn, B.H.4
Tsao, B.P.5
Aderem, A.6
-
70
-
-
33745168605
-
Autoreactive B cell responses to RNA-related antigens due to TLR7 gene duplication
-
Pisitkun P, Deane JA, Difilippantonio MJ, Tarasenko T, Satterthwaite AB, Bolland S. Autoreactive B cell responses to RNA-related antigens due to TLR7 gene duplication. Science 2006; 312: 1669-1672
-
(2006)
Science
, vol.312
, pp. 1669-1672
-
-
Pisitkun, P.1
Deane, J.A.2
Difilippantonio, M.J.3
Tarasenko, T.4
Satterthwaite, A.B.5
Bolland, S.6
-
71
-
-
33846597964
-
Autoreactive B cell responses to RNA-related antigens due to TLR7 gene duplication
-
Ehlers M, Ravetch JV. Autoreactive B cell responses to RNA-related antigens due to TLR7 gene duplication. Trends Immunol 2007; 28: 74-79
-
(2007)
Trends Immunol
, vol.28
, pp. 74-79
-
-
Ehlers, M.1
Ravetch, J.V.2
-
72
-
-
62749123000
-
The role of toll-like receptor pathways in the mechanism of type I diabetes
-
Lien E, Zipris D. The role of toll-like receptor pathways in the mechanism of type I diabetes. Curr Mol Med 2009; 9: 52-68.
-
(2009)
Curr Mol Med
, vol.9
, pp. 52-68
-
-
Lien, E.1
Zipris, D.2
-
74
-
-
33947204489
-
TLR ligands act directly upon T cells to restore proliferation in the absence of protein kinase C-theta signalling and promote autoimmune myocarditis
-
Marsland BJ, Nembrini C, Grun K, Reissmann R, Kurrer M, Leipner C, et al. TLR ligands act directly upon T cells to restore proliferation in the absence of protein kinase C-theta signalling and promote autoimmune myocarditis. J Immunol 2007; 178: 3466-3473
-
(2007)
J Immunol
, vol.178
, pp. 3466-3473
-
-
Marsland, B.J.1
Nembrini, C.2
Grun, K.3
Reissmann, R.4
Kurrer, M.5
Leipner, C.6
-
75
-
-
65549092335
-
Innate immunity and toll-like receptor antagonists: A potential role in the treatment of cardiovascular disease
-
Lin E, Freedman JE, Beaulieu LM. Innate immunity and toll-like receptor antagonists: a potential role in the treatment of cardiovascular disease. Cardiovasc Ther 2009; 27: 117-123
-
(2009)
Cardiovasc Ther
, vol.27
, pp. 117-123
-
-
Lin, E.1
Freedman, J.E.2
Beaulieu, L.M.3
-
76
-
-
34547535297
-
Mechanisms of disease: Toll-like receptors in cardiovascular disease
-
Frantz S, Ertl G, Bauersachs J. Mechanisms of disease: toll-like receptors in cardiovascular disease. Nat Clin Pract Cardiovasc Med 2007; 4: 444-454
-
(2007)
Nat Clin Pract Cardiovasc Med
, vol.4
, pp. 444-454
-
-
Frantz, S.1
Ertl, G.2
Bauersachs, J.3
-
77
-
-
33748296239
-
Immunoprivileged status of the liver controlled by toll-like receptor 3 signaling
-
Lang KS, Georgiev P, Recher M, Navarini AA, Bergthaler A, Heikenwalder M, et al. Immunoprivileged status of the liver controlled by toll-like receptor 3 signaling. J Clin Invest 2006; 116: 2456-2463
-
(2006)
J Clin Invest
, vol.116
, pp. 2456-2463
-
-
Lang, K.S.1
Georgiev, P.2
Recher, M.3
Navarini, A.A.4
Bergthaler, A.5
Heikenwalder, M.6
-
78
-
-
34347255396
-
Suppression of iodide uptake of thyroid hormone synthesis with stimulation of the type I interferon system by double-stranded ribonucleic acid in cultured human thyroid follicles
-
Yamazaki K, Suzuki K, Yamada T, Takeshita F, Matsumoto M, Mitsuhashi T, et al. Suppression of iodide uptake of thyroid hormone synthesis with stimulation of the type I interferon system by double-stranded ribonucleic acid in cultured human thyroid follicles. Endocrinology 2007; 148: 3226-3235
-
(2007)
Endocrinology
, vol.148
, pp. 3226-3235
-
-
Yamazaki, K.1
Suzuki, K.2
Yamada, T.3
Takeshita, F.4
Matsumoto, M.5
Mitsuhashi, T.6
-
79
-
-
47249092785
-
Development of TLR inhibitors for the treatment of autoimmune disease
-
Barrat FJ, Coffman RL. Development of TLR inhibitors for the treatment of autoimmune disease. Immunol Rev 2008; 223: 271-283
-
(2008)
Immunol Rev
, vol.223
, pp. 271-283
-
-
Barrat, F.J.1
Coffman, R.L.2
-
80
-
-
48549088455
-
Anti-microbial peptides and self-DNA in autoimmune skin inflammation
-
Gilliet M, Lande R. Anti-microbial peptides and self-DNA in autoimmune skin inflammation. Curr Opin Immunol 2008; 20: 401-407
-
(2008)
Curr Opin Immunol
, vol.20
, pp. 401-407
-
-
Gilliet, M.1
Lande, R.2
-
81
-
-
61649098667
-
Expression and function of toll-like receptor 8 and tollip in colonic epithelial cells from patients with inflammatory bowel disease
-
Steenholdt C, Andresen L, Pedersen G, Hansen A, Brynskov J. Expression and function of toll-like receptor 8 and tollip in colonic epithelial cells from patients with inflammatory bowel disease. Scand J Gastroenterol 2009; 44:195-204.
-
(2009)
Scand J Gastroenterol
, vol.44
, pp. 195-204
-
-
Steenholdt, C.1
Andresen, L.2
Pedersen, G.3
Hansen, A.4
Brynskov, J.5
-
82
-
-
0034445697
-
Differential alteration in intestinal epithelial cell expression of toll-like receptor 3 (TLR3) and TLR4 in inflammatory bowel disease
-
Cario E, Podolsky DK. Differential alteration in intestinal epithelial cell expression of toll-like receptor 3 (TLR3) and TLR4 in inflammatory bowel disease. Infect Immun 2000; 68: 7010-7017
-
(2000)
Infect Immun
, vol.68
, pp. 7010-7017
-
-
Cario, E.1
Podolsky, D.K.2
-
83
-
-
3442899939
-
NOD2 mediates anti-inflammatory signals induced by TLR2 ligands: Implications for Crohn's disease
-
Netea MG, Kullberg BJ, de Jong B, Franke T, Sprong TH, Naber JP, et al. NOD2 mediates anti-inflammatory signals induced by TLR2 ligands: implications for Crohn's disease. Eur J Immunol 2004; 34: 2052-2059
-
(2004)
Eur J Immunol
, vol.34
, pp. 2052-2059
-
-
Netea, M.G.1
Kullberg, B.J.2
De Jong, B.3
Franke, T.4
Sprong, T.H.5
Naber, J.P.6
-
84
-
-
29744448927
-
Toll-like receptor -1, -2, -6 polymorphisms influence disease extension in inflammatory bowel disease
-
Pierik M, Joosens S, Van Steen K, Van Schverbeek N, Vlietinick R, Rutgeerts P, et al. Toll-like receptor -1, -2, -6 polymorphisms influence disease extension in inflammatory bowel disease. Inflamm Bowel Dis 2006; 12:1-8.
-
(2006)
Inflamm Bowel Dis
, vol.12
, pp. 1-8
-
-
Pierik, M.1
Joosens, S.2
Van Steen, K.3
Van Schverbeek, N.4
Vlietinick, R.5
Rutgeerts, P.6
-
85
-
-
34948854748
-
TLR2, TLR4 and TLR9 polymorphisms and Crohn's disease in a New Zealand Caucasian cohort
-
Hong J, Leany E, Fraser AG, Merriman TR, Vishnu P, Krissansen GM. TLR2, TLR4 and TLR9 polymorphisms and Crohn's disease in a New Zealand Caucasian cohort. J Gastroenterol Hepatol 2007; 22: 1760-1766
-
(2007)
J Gastroenterol Hepatol
, vol.22
, pp. 1760-1766
-
-
Hong, J.1
Leany, E.2
Fraser, A.G.3
Merriman, T.R.4
Vishnu, P.5
Krissansen, G.M.6
-
87
-
-
65649087479
-
Toll-like receptors and rheumatoid arthritis
-
Brentano F, Kyburtz D, Gay S. Toll-like receptors and rheumatoid arthritis. Methods Mol Biol 2009; 517: 329-343
-
(2009)
Methods Mol Biol
, vol.517
, pp. 329-343
-
-
Brentano, F.1
Kyburtz, D.2
Gay, S.3
-
88
-
-
57349192121
-
Overexpression of toll-like receptors 3 and 4 in synovial tissue from patients with early rheumatoid arthritis: Toll-like receptor expression in early and longstanding arthritis
-
Ospelt C, Brentano F, Bergel Y, Stanck J, Kolling C, Takk PP, et al. overexpression of toll-like receptors 3 and 4 in synovial tissue from patients with early rheumatoid arthritis: toll-like receptor expression in early and longstanding arthritis. Arthritis Rheum 2008; 58: 3684-3692
-
(2008)
Arthritis Rheum
, vol.58
, pp. 3684-3692
-
-
Ospelt, C.1
Brentano, F.2
Bergel, Y.3
Stanck, J.4
Kolling, C.5
Takk, P.P.6
-
89
-
-
33750831778
-
TLR4 up-regulation at protein or gene level is pathogenic for lupus-like autoimmune disease
-
Liu B, Yang J, Dai R, Medzhitov MA, Freudenberg PL, Zhang PL, et al. TLR4 up-regulation at protein or gene level is pathogenic for lupus-like autoimmune disease. J Immunol 2006; 177: 6880-6888
-
(2006)
J Immunol
, vol.177
, pp. 6880-6888
-
-
Liu, B.1
Yang, J.2
Dai, R.3
Medzhitov, M.A.4
Freudenberg, P.L.5
Zhang, P.L.6
-
90
-
-
34248577156
-
Involvement of renal tubular toll-like receptor 9 in the development of tubulointerstitial injury in systemic lupus
-
Benigni A, Caroli C, Longaretti L, Gagliardini E, Zoja C, Moioli D, et al. Involvement of renal tubular toll-like receptor 9 in the development of tubulointerstitial injury in systemic lupus. Arthritis Rheum 2007; 56: 1569-1578
-
(2007)
Arthritis Rheum
, vol.56
, pp. 1569-1578
-
-
Benigni, A.1
Caroli, C.2
Longaretti, L.3
Gagliardini, E.4
Zoja, C.5
Moioli, D.6
-
91
-
-
34247272370
-
Toll-like receptor: Emerging concepts in kidney disease
-
Anders H, Schlöndorff D. Toll-like receptor: emerging concepts in kidney disease. Curr Opin Nephrol Hypertens 2007; 16: 177-183
-
(2007)
Curr Opin Nephrol Hypertens
, vol.16
, pp. 177-183
-
-
Anders, H.1
Schlöndorff, D.2
-
92
-
-
58649104191
-
Significance of toll-like receptors expression in tumor growth and speading: A short review
-
Zeromski J, Mozer-Lisewska I, Kaczmarek M. Significance of toll-like receptors expression in tumor growth and speading: a short review. Cancer Microenviron 2008; 1: 37-42.
-
(2008)
Cancer Microenviron
, vol.1
, pp. 37-42
-
-
Zeromski, J.1
Mozer-Lisewska, I.2
Kaczmarek, M.3
-
93
-
-
63449126998
-
Toll-like receptors and their role in carcinogenesis and anti-tumor treatment
-
Wolska A, Lech-Maranda E, Robak T. Toll-like receptors and their role in carcinogenesis and anti-tumor treatment. Cell Mol Biol Lett 2009; 14: 248-272
-
(2009)
Cell Mol Biol Lett
, vol.14
, pp. 248-272
-
-
Wolska, A.1
Lech-Maranda, E.2
Robak, T.3
-
94
-
-
34848903051
-
Toll-like receptors in tumor immunotherapy
-
Paulus CM, Kaiser A, Wresinsli C, Hinrichs CS, Cassard L, Boni A, et al. Toll-like receptors in tumor immunotherapy. Clin Cancer Res 2007; 13: 5280-5289
-
(2007)
Clin Cancer Res
, vol.13
, pp. 5280-5289
-
-
Paulus, C.M.1
Kaiser, A.2
Wresinsli, C.3
Hinrichs, C.S.4
Cassard, L.5
Boni, A.6
-
95
-
-
3042550183
-
Toll-like receptors and immune response in allergic disease
-
Gangloff SC, Guenounou M. Toll-like receptors and immune response in allergic disease. Clin Rev Allergy Immunol 2004; 26: 115-125
-
(2004)
Clin Rev Allergy Immunol
, vol.26
, pp. 115-125
-
-
Gangloff, S.C.1
Guenounou, M.2
-
96
-
-
15044346721
-
Toll-like receptor 4 or 2 agonists decrease allergic inflammation
-
Velasco G, Campo M, Manrique OJ, Bellou A, He H, Arestides RS, et al. Toll-like receptor 4 or 2 agonists decrease allergic inflammation. Am J Respir Cell Mol Biol 2005; 32: 218-224
-
(2005)
Am J Respir Cell Mol Biol
, vol.32
, pp. 218-224
-
-
Velasco, G.1
Campo, M.2
Manrique, O.J.3
Bellou, A.4
He, H.5
Arestides, R.S.6
-
97
-
-
58249094472
-
Influence of toll-like receptor ligands on the dendritic cell-T cell interactions, therapeutic options for allergic diseases? Mini-review
-
Bullens DM, Ceuppen JL. Influence of toll-like receptor ligands on the dendritic cell-T cell interactions, therapeutic options for allergic diseases? Mini-review. Inflamm Allergy Drug Targets 2008; 7: 211-216
-
(2008)
Inflamm Allergy Drug Targets
, vol.7
, pp. 211-216
-
-
Bullens, D.M.1
Ceuppen, J.L.2
-
98
-
-
34548279776
-
Toll-like receptors in older adults
-
Van Duin D, Shaw AC. Toll-like receptors in older adults. J Am Geriatr Sox 2007; 55: 1438-1444
-
(2007)
J Am Geriatr Sox
, vol.55
, pp. 1438-1444
-
-
Van Duin, D.1
Shaw, A.C.2
-
99
-
-
33750574347
-
Therapeutic targeting of Toll-like receptors in gastrointestinal inflammation
-
Ishihara S, Rumi MAK, Ortega-Cava CF, Kazumori H, Kadowaki Y, Ishimura N, et al. Therapeutic targeting of Toll-like receptors in gastrointestinal inflammation. Curr Pharm Des 2006; 12: 4215-4228.
-
(2006)
Curr Pharm Des
, vol.12
, pp. 4215-4228
-
-
Ishihara, S.1
Rumi, M.A.K.2
Ortega-Cava, C.F.3
Kazumori, H.4
Kadowaki, Y.5
Ishimura, N.6
-
101
-
-
33845786018
-
Current and future drugs targeting one class of innate immunity receptors: The Toll-like receptors
-
Romagne F. Current and future drugs targeting one class of innate immunity receptors: the Toll-like receptors. Drug Discov Today 2007; 12: 80-87.
-
(2007)
Drug Discov Today
, vol.12
, pp. 80-87
-
-
Romagne, F.1
-
102
-
-
35648930568
-
Update on toll-like receptor-directed therapies for human disease
-
Tse K, Horner AA. Update on toll-like receptor-directed therapies for human disease. Ann Rheum Dis 2007; 66: 77-80.
-
(2007)
Ann Rheum Dis
, vol.66
, pp. 77-80
-
-
Tse, K.1
Horner, A.A.2
-
103
-
-
38649123396
-
The future of toll-like receptors therapeutics
-
Parkinson T. The future of toll-like receptors therapeutics. Curr Opin Mol Ther 2008; 10: 21-31.
-
(2008)
Curr Opin Mol Ther
, vol.10
, pp. 21-31
-
-
Parkinson, T.1
-
104
-
-
0032567027
-
Immunostimulatory DNA is a potent mucosal adjuvant
-
Horner AA, Ronhaghy A, Cheng PM, Nguyen MD, Cho HJ, Broide D, et al. Immunostimulatory DNA is a potent mucosal adjuvant. Cell Immunol 1998; 190: 77-82.
-
(1998)
Cell Immunol
, vol.190
, pp. 77-82
-
-
Horner, A.A.1
Ronhaghy, A.2
Cheng, P.M.3
Nguyen, M.D.4
Cho, H.J.5
Broide, D.6
-
106
-
-
28344457315
-
Comparison of the safety and immunogenicity of hepatitis B virus surface antigen co-administered with an immunostimulatory phosphorothioate oligonucleotide and a licensed hepatitis B vaccine in healthy young adults
-
Halperin SA, Dobson S, McNeil S, Langley JM, Smith B, McCall-Sani R, et al. Comparison of the safety and immunogenicity of hepatitis B virus surface antigen co-administered with an immunostimulatory phosphorothioate oligonucleotide and a licensed hepatitis B vaccine in healthy young adults. Vaccine 2006; 24: 20-26.
-
(2006)
Vaccine
, vol.24
, pp. 20-26
-
-
Halperin, S.A.1
Dobson, S.2
McNeil, S.3
Langley, J.M.4
Smith, B.5
McCall-Sani, R.6
-
107
-
-
20644450804
-
Negative regulation of Toll-like receptor-mediated immune responses
-
Liew F, Xu D, Brint EK, O' Neill AJ. Negative regulation of Toll-like receptor-mediated immune responses. Nature 2006; 5: 446-458
-
(2006)
Nature
, vol.5
, pp. 446-458
-
-
Liew, F.1
Xu, D.2
Brint, E.K.3
O'Neill, A.J.4
-
108
-
-
10744233851
-
Soluble forms of Toll-like receptors (TLR)2 capable of modulating TLR2 signaling are present in human plasma and breast milk
-
LeBourder, E, Rey-Nores JE, Rushmere NK, Grigorov M, Lawn SD, Affolter M, et al. Soluble forms of Toll-like receptors (TLR)2 capable of modulating TLR2 signaling are present in human plasma and breast milk. J Immunol 2003; 171: 6680-6689
-
(2003)
J Immunol
, vol.171
, pp. 6680-6689
-
-
Lebourder, E.1
Rey-Nores, J.E.2
Rushmere, N.K.3
Grigorov, M.4
Lawn, S.D.5
Affolter, M.6
-
109
-
-
0034672088
-
Cutting edge: Naturally occurring soluble form of mouse toll-like receptor 4 inhibits lipopolysaccharide signalling
-
Iwami, KI, Matsuguchi T, Masuda A, Kikuchi T, Musikacharoen T, Yoshikai Y. Cutting edge: naturally occurring soluble form of mouse toll-like receptor 4 inhibits lipopolysaccharide signalling. J Immunol 2000; 165: 6682-6686
-
(2000)
J Immunol
, vol.165
, pp. 6682-6686
-
-
Iwami, K.I.1
Matsuguchi, T.2
Masuda, A.3
Kikuchi, T.4
Musikacharoen, T.5
Yoshikai, Y.6
-
110
-
-
2942721674
-
ST2 is an inhibitor of interleukin 1 receptor and toll-like receptor 4 signaling and maintains endotoxin tolerance
-
Brint EK, Xu D, Liu H, Dunne A, McKenzie AN, O'Neill LA, et al. ST2 is an inhibitor of interleukin 1 receptor and toll-like receptor 4 signaling and maintains endotoxin tolerance. Nat Immunol 2004; 5: 373-379
-
(2004)
Nat Immunol
, vol.5
, pp. 373-379
-
-
Brint, E.K.1
Xu, D.2
Liu, H.3
Dunne, A.4
McKenzie, A.N.5
O'Neill, L.A.6
-
111
-
-
21644477461
-
SIGIRR inhibits interleukin-1 receptor- and toll-like receptor 4- mediated signalling through different mechanisms
-
Qin J, Quian Y, Yao J, Grace C, Li X. SIGIRR inhibits interleukin-1 receptor- and toll-like receptor 4- mediated signalling through different mechanisms. J Biol Chem 2005; 280: 25233-25241
-
(2005)
J Biol Chem
, vol.280
, pp. 25233-25241
-
-
Qin, J.1
Quian, Y.2
Yao, J.3
Grace, C.4
Li, X.5
-
112
-
-
64849087206
-
The essential role of single Ig IL-1 receptor-related molecule/toll IL-1R8 in regulation of Th2 immune response
-
Bulek K, Swaidani S, Qin J, Lu Y, Gulen MF, Herjan T, et al. The essential role of single Ig IL-1 receptor-related molecule/toll IL-1R8 in regulation of Th2 immune response. J Immunol 2009; 182: 2601-2609
-
(2009)
J Immunol
, vol.182
, pp. 2601-2609
-
-
Bulek, K.1
Swaidani, S.2
Qin, J.3
Lu, Y.4
Gulen, M.F.5
Herjan, T.6
-
113
-
-
20644450101
-
Negative regulation of toll-like receptor 4 signaling by the toll-like receptor homolog RP105
-
Divanovik S, Trompette A, Atabani SF, Madan R, Golenbock DT, Visintin A, et al. Negative regulation of toll-like receptor 4 signaling by the toll-like receptor homolog RP105. Nat Immunol 2005; 6: 571-578
-
(2005)
Nat Immunol
, vol.6
, pp. 571-578
-
-
Divanovik, S.1
Trompette, A.2
Atabani, S.F.3
Madan, R.4
Golenbock, D.T.5
Visintin, A.6
-
114
-
-
10344260656
-
TRAIL-R as a negative regulator of innate immune cell responses
-
Diehl GE, Yue HH, Hsieh K, Kuang AA, Ho M, Morici LA, et al. TRAIL-R as a negative regulator of innate immune cell responses. Immunity 2004; 21: 877-889
-
(2004)
Immunity
, vol.21
, pp. 877-889
-
-
Diehl, G.E.1
Yue, H.H.2
Hsieh, K.3
Kuang, A.A.4
Ho, M.5
Morici, L.A.6
-
115
-
-
62649124147
-
Negative regulation of toll-like receptor signalling pathway
-
Wang J, Hu Y, Deng WW, Sun B. Negative regulation of toll-like receptor signalling pathway. Microbes Infect 2009; 11: 321-327
-
(2009)
Microbes Infect
, vol.11
, pp. 321-327
-
-
Wang, J.1
Hu, Y.2
Deng, W.W.3
Sun, B.4
-
116
-
-
0037454946
-
Inhibition of interleukin 1 receptor/toll-like receptor signalling through the alternatively spliced, short form of MyD88 is due to its failure to recruit IRAK-4
-
Burns K, Janssens S, Brissoni B, Olivos N, Beyaert R, Tschopp J. Inhibition of interleukin 1 receptor/toll-like receptor signalling through the alternatively spliced, short form of MyD88 is due to its failure to recruit IRAK-4. J Exp Med 2003; 197: 263-268
-
(2003)
J Exp Med
, vol.197
, pp. 263-268
-
-
Burns, K.1
Janssens, S.2
Brissoni, B.3
Olivos, N.4
Beyaert, R.5
Tschopp, J.6
-
117
-
-
34548436187
-
The negative regulation of toll-like receptor and associated pathways
-
Lang T, Mansell A. The negative regulation of toll-like receptor and associated pathways. Immunol Cell Biol 2007; 85: 425-434
-
(2007)
Immunol Cell Biol
, vol.85
, pp. 425-434
-
-
Lang, T.1
Mansell, A.2
-
118
-
-
33748880024
-
DisSARMing toll-like receptor signaling
-
O'Neill LA. DisSARMing toll-like receptor signaling. Nat Immunol 2006; 7: 1023-1025
-
(2006)
Nat Immunol
, vol.7
, pp. 1023-1025
-
-
O'Neill, L.A.1
-
119
-
-
31144453399
-
Flightless I homolog negatively modulates the TLR pathway
-
Wang T, Chuang TH, Ronni T, Gu S, Du YC, Cai H, et al. Flightless I homolog negatively modulates the TLR pathway. J Immunol 2006; 176: 1355-1362
-
(2006)
J Immunol
, vol.176
, pp. 1355-1362
-
-
Wang, T.1
Chuang, T.H.2
Ronni, T.3
Gu, S.4
Du, Y.C.5
Cai, H.6
-
120
-
-
3042686382
-
The murine IRAK2 gene encodes four alternatively spliced isoforms, two of which are inhibitory
-
Hardy MP, O'Neill LA. The murine IRAK2 gene encodes four alternatively spliced isoforms, two of which are inhibitory. J Biol Chem 2004; 279: 27699-27708
-
(2004)
J Biol Chem
, vol.279
, pp. 27699-27708
-
-
Hardy, M.P.1
O'Neill, L.A.2
-
121
-
-
23844461233
-
TRAF4 acts as a silencer in TLR-mediated signalling through the association with TRAF6 and TRIF
-
Takeshita F, Ishii KJ, Kobiyama K, Kojima Y, Coban C, Sasaki S, et al. TRAF4 acts as a silencer in TLR-mediated signalling through the association with TRAF6 and TRIF. Eur J Immunol 2005; 35: 2477-2485
-
(2005)
Eur J Immunol
, vol.35
, pp. 2477-2485
-
-
Takeshita, F.1
Ishii, K.J.2
Kobiyama, K.3
Kojima, Y.4
Coban, C.5
Sasaki, S.6
-
122
-
-
0036510366
-
Negative regulation of toll-like receptor-mediated signalling by Tollip
-
Zhang G, Ghosh S. Negative regulation of toll-like receptor-mediated signalling by Tollip. J Biol Chem 2002; 277: 7059-7065
-
(2002)
J Biol Chem
, vol.277
, pp. 7059-7065
-
-
Zhang, G.1
Ghosh, S.2
-
123
-
-
5444223519
-
The ubiquitin-modifying enzyme A20 is required for termination of toll-like receptor responses
-
Boone DL, Turner EE, Lee EG, Ahmad RC, Wheeler MT, Tsui C, et al. The ubiquitin-modifying enzyme A20 is required for termination of toll-like receptor responses. Nat Immunol 2004; 5: 1052-1060
-
(2004)
Nat Immunol
, vol.5
, pp. 1052-1060
-
-
Boone, D.L.1
Turner, E.E.2
Lee, E.G.3
Ahmad, R.C.4
Wheeler, M.T.5
Tsui, C.6
-
124
-
-
34247280398
-
β-arrestins 1 and 2 differentially regulate LPS-induced signalling and pro-inflammatory gene expression
-
Fan H, Luttrell LM, Tempel GE, Senn JJ, Halushka PV, Cook JA. β-arrestins 1 and 2 differentially regulate LPS-induced signalling and pro-inflammatory gene expression. Mol Immunol 2007; 44: 3092-3099
-
(2007)
Mol Immunol
, vol.44
, pp. 3092-3099
-
-
Fan, H.1
Luttrell, L.M.2
Tempel, G.E.3
Senn, J.J.4
Halushka, P.V.5
Cook, J.A.6
-
125
-
-
33846984613
-
LIND/ABIN-3 is a novel lipopolysaccharide-inducible inhibitor of NF-κB activation
-
Wullaert A, Verstrepen L, Van Huffel S, Adib-Conquy M, Cornelis S, Kreike M, et al. LIND/ABIN-3 is a novel lipopolysaccharide-inducible inhibitor of NF-κB activation. J Biol Chem 2007; 282: 81-90.
-
(2007)
J Biol Chem
, vol.282
, pp. 81-90
-
-
Wullaert, A.1
Verstrepen, L.2
Van Huffel, S.3
Adib-Conquy, M.4
Cornelis, S.5
Kreike, M.6
-
126
-
-
29244467708
-
FLN29, a novel interferon- and LPS-inducible gene acting as a negative regulator of toll-like receptor signalling
-
Mashima R, Saek K, Aki D, Minoda Y, Takaki H, Kobayashi T, et al. FLN29, a novel interferon- and LPS-inducible gene acting as a negative regulator of toll-like receptor signalling. J Biol Chem 2005; 280: 41289-41297
-
(2005)
J Biol Chem
, vol.280
, pp. 41289-41297
-
-
Mashima, R.1
Saek, K.2
Aki, D.3
Minoda, Y.4
Takaki, H.5
Kobayashi, T.6
-
127
-
-
28844460239
-
The tumor suppressor cylindromatosis (CYLD) acts as a negative regulator for toll-like receptor 2 signaling via negative cross-talk with TRAF6 and TRAF7
-
Yoshida H, Jono H, Kai H, Li LD. The tumor suppressor cylindromatosis (CYLD) acts as a negative regulator for toll-like receptor 2 signaling via negative cross-talk with TRAF6 and TRAF7. J Biol Chem 2005; 280: 41111-41121
-
(2005)
J Biol Chem
, vol.280
, pp. 41111-41121
-
-
Yoshida, H.1
Jono, H.2
Kai, H.3
Li, L.D.4
-
128
-
-
33845438110
-
SHP-2 phosphatase negatively regulates the TRIF adaptor proteindependent type I interferon and proinflammatory cytokine production
-
An H, Zhao W, Hou J, Zhang Y, Xie Y, Xu H, et al. SHP-2 phosphatase negatively regulates the TRIF adaptor proteindependent type I interferon and proinflammatory cytokine production. Immunity 2006; 25: 918-929
-
(2006)
Immunity
, vol.25
, pp. 918-929
-
-
An, H.1
Zhao, W.2
Hou, J.3
Zhang, Y.4
Xie, Y.5
Xu, H.6
-
129
-
-
0347955360
-
Regulation of NF-κB signalling by Pin1-dependent prolyl isomerization and ubiquitin-mediated proteolysis of p65/RelA
-
Ryo A, Suizu F, Yoshida Y, Perrem K, Liou YC, Wulf G, et al. Regulation of NF-κB signalling by Pin1-dependent prolyl isomerization and ubiquitin-mediated proteolysis of p65/RelA. Mol Cell 2003; 12: 1413-1426
-
(2003)
Mol Cell
, vol.12
, pp. 1413-1426
-
-
Ryo, A.1
Suizu, F.2
Yoshida, Y.3
Perrem, K.4
Liou, Y.C.5
Wulf, G.6
-
130
-
-
33744499683
-
Negative regulator of interferon-regulatory factor 3-dependent innate antiviral response by the prolylisomerase Pin1
-
Saitoh T, Tun-Kyi A, Ryo A, Yamamoto M, Finn G, Fujita T, et al. Negative regulator of interferon-regulatory factor 3-dependent innate antiviral response by the prolylisomerase Pin1. Nat Immunol 2006; 7: 598-605.
-
(2006)
Nat Immunol
, vol.7
, pp. 598-605
-
-
Saitoh, T.1
Tun-Kyi, A.2
Ryo, A.3
Yamamoto, M.4
Finn, G.5
Fujita, T.6
-
131
-
-
0037629646
-
PI3K and negative regulation of TLR signalling
-
Fukao T, Koyasu S. PI3K and negative regulation of TLR signalling. Trends Immunol 2003; 24: 358-363
-
(2003)
Trends Immunol
, vol.24
, pp. 358-363
-
-
Fukao, T.1
Koyasu, S.2
-
132
-
-
33646547951
-
Systems biology approaches identify ATF3 as a negative regulator of toll-like receptor-4
-
Gilchrist M, Thorsson V, Li B, Rust AG, Korb M, Kennedy K, et al. Systems biology approaches identify ATF3 as a negative regulator of toll-like receptor-4. Nature 2006; 441: 173-178
-
(2006)
Nature
, vol.441
, pp. 173-178
-
-
Gilchrist, M.1
Thorsson, V.2
Li, B.3
Rust, A.G.4
Korb, M.5
Kennedy, K.6
-
133
-
-
34547815755
-
Negative regulation of toll-like receptor signalling by NF-κB p50 ubiquitination blockade
-
Carmody RJ, Ruan Q, Palmer S, Hilliard B, Chen YH. Negative regulation of toll-like receptor signalling by NF-κB p50 ubiquitination blockade. Science 2007; 317: 675-678
-
(2007)
Science
, vol.317
, pp. 675-678
-
-
Carmody, R.J.1
Ruan, Q.2
Palmer, S.3
Hilliard, B.4
Chen, Y.H.5
-
134
-
-
3142654210
-
Interferences, questions and possibilities in toll-like receptors signalling
-
Beutler B. Interferences, questions and possibilities in toll-like receptors signalling. Nature 2004; 430: 257-263
-
(2004)
Nature
, vol.430
, pp. 257-263
-
-
Beutler, B.1
-
135
-
-
57149107350
-
Gene-specific control of the TLR-induced inflammatory response
-
Foster SL, Medzhitov R. Gene-specific control of the TLR-induced inflammatory response. Clin Immunol 2009; 130: 7-15.
-
(2009)
Clin Immunol
, vol.130
, pp. 7-15
-
-
Foster, S.L.1
Medzhitov, R.2
-
136
-
-
43449097249
-
Lypopolysaccharide stimulates proopiomelanocortin gene expression in AtT20 corticotroph cells
-
Iwasaki Y, Taguchi T, Nishiyama M, Asai M, Yoshida M, Kambayashi M, et al. Lypopolysaccharide stimulates proopiomelanocortin gene expression in AtT20 corticotroph cells. Endocr J 2008; 55: 285-290
-
(2008)
Endocr J
, vol.55
, pp. 285-290
-
-
Iwasaki, Y.1
Taguchi, T.2
Nishiyama, M.3
Asai, M.4
Yoshida, M.5
Kambayashi, M.6
-
137
-
-
9344241806
-
Impaired adrenal stress response in toll-like receptor 2-deficient mice
-
Bornstein S, Zacharowski P, Schumann R, Barthel A, Tran N, Papewalis C, et al. Impaired adrenal stress response in toll-like receptor 2-deficient mice. Proc Natl Acad Sci USA 2004; 101: 16695-16700
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 16695-16700
-
-
Bornstein, S.1
Zacharowski, P.2
Schumann, R.3
Barthel, A.4
Tran, N.5
Papewalis, C.6
-
138
-
-
33646590972
-
Toll-like receptor 4 plays a crucial role in the immune-adrenal response to systemic inflammatory response syndrome
-
Zacharowski K, Zararowski P, Koch A, Baban A, Tran N, Berkels R, et al. Toll-like receptor 4 plays a crucial role in the immune-adrenal response to systemic inflammatory response syndrome. Proc Natl Acad Sci USA 2006; 103: 6392-6397
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 6392-6397
-
-
Zacharowski, K.1
Zararowski, P.2
Koch, A.3
Baban, A.4
Tran, N.5
Berkels, R.6
-
139
-
-
33947667036
-
Activation of enteroendocrine cells via TLRs induces hormone, chemokine, and defensin secretion
-
Palazzo M, Balsari A, Rossini A, Selleri S, Calcaterra C, Gariboldi S, et al. Activation of enteroendocrine cells via TLRs induces hormone, chemokine, and defensin secretion. J Immunol 2007; 178: 4296-4303
-
(2007)
J Immunol
, vol.178
, pp. 4296-4303
-
-
Palazzo, M.1
Balsari, A.2
Rossini, A.3
Selleri, S.4
Calcaterra, C.5
Gariboldi, S.6
-
140
-
-
33645284772
-
Neural regulation of innate immunity: A coordinated nonspecific host response to pathogens
-
Sternberg E. Neural regulation of innate immunity: a coordinated nonspecific host response to pathogens. Nat Rev Immunol 2006; 6: 318-329
-
(2006)
Nat Rev Immunol
, vol.6
, pp. 318-329
-
-
Sternberg, E.1
-
141
-
-
34548429606
-
Anti-inflammatory neuropeptide receptors: New therapeutic targets for immune disorders?
-
Gonzalez-Rey E, Delgado M. Anti-inflammatory neuropeptide receptors: new therapeutic targets for immune disorders? Trends Pharmacol Sci 2007; 28: 482-491
-
(2007)
Trends Pharmacol Sci
, vol.28
, pp. 482-491
-
-
Gonzalez-Rey, E.1
Delgado, M.2
-
142
-
-
0037458585
-
CAMP-induced interleukin-10 promoter activation depends on CAAT/enhancer-binding protein expression and monocytic differentiation
-
Brenner S, Prösch S, Schenke-Layland K, Riese U, Gausmann U, Platzer C. cAMP-induced interleukin-10 promoter activation depends on CAAT/enhancer-binding protein expression and monocytic differentiation. J Biol Chem 2003; 278: 5597-5604
-
(2003)
J Biol Chem
, vol.278
, pp. 5597-5604
-
-
Brenner, S.1
Prösch, S.2
Schenke-Layland, K.3
Riese, U.4
Gausmann, U.5
Platzer, C.6
-
143
-
-
46949110015
-
Activation of cyclic-AMP response element binding protein contributes to adiponectin-stimulated interleukin-10 expression in raw 264.7 macrophages
-
Park P, Huang H, McMullen M, Bryan K, Nagy L. Activation of cyclic-AMP response element binding protein contributes to adiponectin-stimulated interleukin-10 expression in raw 264.7 macrophages. J Leukoc Biol 2008; 83: 1258-1266
-
(2008)
J Leukoc Biol
, vol.83
, pp. 1258-1266
-
-
Park, P.1
Huang, H.2
McMullen, M.3
Bryan, K.4
Nagy, L.5
-
144
-
-
36549073087
-
Hormonal control of the renal immune response and antibacterial host defence by arginine vasopressin
-
Chassin C, Hornef M, Bens M, Lotz M, Goujon J-M, Vimont S, et al. Hormonal control of the renal immune response and antibacterial host defence by arginine vasopressin. J Exp Med 2007; 204: 2837-2852
-
(2007)
J Exp Med
, vol.204
, pp. 2837-2852
-
-
Chassin, C.1
Hornef, M.2
Bens, M.3
Lotz, M.4
Goujon, J.-M.5
Vimont, S.6
-
145
-
-
34250853401
-
Negative regulation of TLR responses by the neuropeptide CGRP Is mediated by the transcriptional repressor ICER
-
Harzenetter M, Novotny A, Gais P, Molina C, Altmayr F, Holzmann B. Negative regulation of TLR responses by the neuropeptide CGRP Is mediated by the transcriptional repressor ICER. J Immunol 2007; 179: 607-615
-
(2007)
J Immunol
, vol.179
, pp. 607-615
-
-
Harzenetter, M.1
Novotny, A.2
Gais, P.3
Molina, C.4
Altmayr, F.5
Holzmann, B.6
-
146
-
-
0041856376
-
α-melanocyte-stimulating hormone inhibits lipopolysaccharide induced tumor necrosis factor-α production in leukocytes by modulating protein kinase A, p38 kinase, and nuclear factor κB signaling pathways
-
Yoon SW, Goh SH, Chun JS, Cho EW, Lee MK, Kim KL, et al. α-melanocyte-stimulating hormone inhibits lipopolysaccharide induced tumor necrosis factor-α production in leukocytes by modulating protein kinase A, p38 kinase, and nuclear factor κB signaling pathways. J Biol Chem 2003; 278: 32914-32920
-
(2003)
J Biol Chem
, vol.278
, pp. 32914-32920
-
-
Yoon, S.W.1
Goh, S.H.2
Chun, J.S.3
Cho, E.W.4
Lee, M.K.5
Kim, K.L.6
-
148
-
-
0038362292
-
When ubiquitin meets ubiquitin receptors: A signalling connection
-
Di Fiore P, Polo S, Hofmann K. When ubiquitin meets ubiquitin receptors: a signalling connection. Nat Rev Mol Cell Biol 2003; 4: 491-497
-
(2003)
Nat Rev Mol Cell Biol
, vol.4
, pp. 491-497
-
-
Di Fiore, P.1
Polo, S.2
Hofmann, K.3
-
149
-
-
2942554958
-
β-Arrestin inhibits NF-κB activity by means of its interaction with the NF-κB inhibitor IkBα
-
Witherow D, Garrison T, Miller W, Lefkowitz R. β-Arrestin inhibits NF-κB activity by means of its interaction with the NF-κB inhibitor IkBα. Proc Natl Acad Sci USA 2004; 101: 8603-8607
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 8603-8607
-
-
Witherow, D.1
Garrison, T.2
Miller, W.3
Lefkowitz, R.4
-
150
-
-
2342510314
-
Identification of β- Arrestin2 as a G protein-coupled receptor-stimulated regulator of NF-κB pathways
-
Gao H, Sun Y, Wu Y, Luan B, Wang Y, Qu B, et al. Identification of β- arrestin2 as a G protein-coupled receptor-stimulated regulator of NF-κB pathways. Mol Cell 2004; 14: 303-317
-
(2004)
Mol Cell
, vol.14
, pp. 303-317
-
-
Gao, H.1
Sun, Y.2
Wu, Y.3
Luan, B.4
Wang, Y.5
Qu, B.6
-
151
-
-
31344463886
-
Association of β-arrestin and TRAF6 negatively regulates toll-like receptorinterleukin 1 receptor signaling
-
Wang Y, Tang Y, Teng L, Wu Y, Zhao X, Pei G. Association of β-arrestin and TRAF6 negatively regulates toll-like receptorinterleukin 1 receptor signaling. Nat Immunol 2006; 7: 139-147
-
(2006)
Nat Immunol
, vol.7
, pp. 139-147
-
-
Wang, Y.1
Tang, Y.2
Teng, L.3
Wu, Y.4
Zhao, X.5
Pei, G.6
-
152
-
-
17044392279
-
The immunomodulating neuropeptide alpha-melanocyte-stimulating hormone (α-MSH) suppresses LPS-stimulated TLR4 with IRAK-M in macrophages
-
Taylor A. The immunomodulating neuropeptide alpha-melanocyte-stimulating hormone (α-MSH) suppresses LPS-stimulated TLR4 with IRAK-M in macrophages. J Neuroimmunol 2005; 162: 43-50.
-
(2005)
J Neuroimmunol
, vol.162
, pp. 43-50
-
-
Taylor, A.1
-
153
-
-
31144475602
-
Corticotropin-releasing factor and the urocortins induce the expression of TLR4 in macrophages via activation of the transcription factors PU.1 and AP-1
-
Tsatsanis C, Androulidaki A, Alissafi T, Charalampopoulos I, Dermitzaki E, Roger T, et al. Corticotropin-releasing factor and the urocortins induce the expression of TLR4 in macrophages via activation of the transcription factors PU.1 and AP-1. J Immunol 2006; 176: 1869-1877
-
(2006)
J Immunol
, vol.176
, pp. 1869-1877
-
-
Tsatsanis, C.1
Androulidaki, A.2
Alissafi, T.3
Charalampopoulos, I.4
Dermitzaki, E.5
Roger, T.6
-
154
-
-
0014965359
-
Potent peripheral splanchnic vasodilator peptide from normal gut
-
Said SI, Mutt V. Potent peripheral splanchnic vasodilator peptide from normal gut. Nature 1970; 225: 863-864
-
(1970)
Nature
, vol.225
, pp. 863-864
-
-
Said, S.I.1
Mutt, V.2
-
156
-
-
0031439774
-
Vasoactive intestinal polypeptide (VIP) innervation of rat thymus and lymph nodes
-
Bellinger DL, Lorton D, Horn L, Brouxhon S, Felten SY, Felten DL. Vasoactive intestinal polypeptide (VIP) innervation of rat thymus and lymph nodes. Peptides 1997; 8: 1139-1149
-
(1997)
Peptides
, vol.8
, pp. 1139-1149
-
-
Bellinger, D.L.1
Lorton, D.2
Horn, L.3
Brouxhon, S.4
Felten, S.Y.5
Felten, D.L.6
-
157
-
-
0018116215
-
Release of vasoactive intestinal polypeptide in mast cells by histamine liberators
-
Cutz E, Chan W, Track NS, Gooth A, Said SI. Release of vasoactive intestinal polypeptide in mast cells by histamine liberators. Nature 1978; 275: 661-662
-
(1978)
Nature
, vol.275
, pp. 661-662
-
-
Cutz, E.1
Chan, W.2
Track, N.S.3
Gooth, A.4
Said, S.I.5
-
158
-
-
0018939041
-
Vasoactive intestinal polypeptide as a biochemical marker for polymorphonuclear leukocytes
-
O'Dorisio MS, O'Dorisio TM, Cataland S, Balcerzak SP. Vasoactive intestinal polypeptide as a biochemical marker for polymorphonuclear leukocytes. J Lab Clin Med 1980; 96: 666-672
-
(1980)
J Lab Clin Med
, vol.96
, pp. 666-672
-
-
O'Dorisio, M.S.1
O'Dorisio, T.M.2
Cataland, S.3
Balcerzak, S.P.4
-
159
-
-
0025174201
-
Detection of vasoactive intestinal peptide and localization of its mRNA within granulomas of murine schistosomiasis
-
Weinstock JV, Blum AM. Detection of vasoactive intestinal peptide and localization of its mRNA within granulomas of murine schistosomiasis. Cell Immunol 1990; 125: 291-300.
-
(1990)
Cell Immunol
, vol.125
, pp. 291-300
-
-
Weinstock, J.V.1
Blum, A.M.2
-
160
-
-
0025103801
-
Demonstration of immunoreactive vasoactive intestinal peptide (IR-VIP) and somatostatin (IR-SOM) in rat thymus
-
Gomariz RP, Lorenzo MJ, Cacicedo L, Zapata AG. Demonstration of immunoreactive vasoactive intestinal peptide (IR-VIP) and somatostatin (IR-SOM) in rat thymus. Brain Behav Immun 1990; 4: 151-161
-
(1990)
Brain Behav Immun
, vol.4
, pp. 151-161
-
-
Gomariz, R.P.1
Lorenzo, M.J.2
Cacicedo, L.3
Zapata, A.G.4
-
161
-
-
0027750913
-
VIP gene expression in rat thymus and spleen
-
Gomariz RP, Delgado M, Naranjo JR, Mellstrom B, Tormo A, Mata F, et al. VIP gene expression in rat thymus and spleen. Brain Behav Immun 1992; 7: 271-278
-
(1992)
Brain Behav Immun
, vol.7
, pp. 271-278
-
-
Gomariz, R.P.1
Delgado, M.2
Naranjo, J.R.3
Mellstrom, B.4
Tormo, A.5
Mata, F.6
-
162
-
-
0028060385
-
Lymphoid cells subpopulations containing vasoactive intestinal peptide
-
Leceta J, Martinez J, Delgado M, Garrido E, Gomariz RP. Lymphoid cells subpopulations containing vasoactive intestinal peptide. Peptides 1994; 15: 791-797
-
(1994)
Peptides
, vol.15
, pp. 791-797
-
-
Leceta, J.1
Martinez, J.2
Delgado, M.3
Garrido, E.4
Gomariz, R.P.5
-
163
-
-
0032891615
-
Regulation of VIP production and secretion by murine lymphocytes
-
Martínez C, Delgado M, Abad C, Gomariz RP, Ganea D, Leceta J. Regulation of VIP production and secretion by murine lymphocytes. J Neuroimmunol 1999; 93: 126-138
-
(1999)
J Neuroimmunol
, vol.93
, pp. 126-138
-
-
Martínez, C.1
Delgado, M.2
Abad, C.3
Gomariz, R.P.4
Ganea, D.5
Leceta, J.6
-
164
-
-
0001585265
-
Nomenclature of receptors for vasoactive intestinal peptide (VIP) and pituitary adenylate cyclase activating polypeptide (PACAP)
-
Harmar AJ, Arimura A, Gozes I, Journot L, Laburthe M, Pisegna JR, et al. Nomenclature of receptors for vasoactive intestinal peptide (VIP) and pituitary adenylate cyclase activating polypeptide (PACAP). Pharmacol Rev 1998; 50: 625-627
-
(1998)
Pharmacol Rev
, vol.50
, pp. 625-627
-
-
Harmar, A.J.1
Arimura, A.2
Gozes, I.3
Journot, L.4
Laburthe, M.5
Pisegna, J.R.6
-
165
-
-
0036166975
-
Vasoactive intestinal peptide in the immune system: Potential therapeutic role in inflammatory and autoimmune diseases
-
Delgado M, Abad C, Martinez C, Juarranz Y, Arranz A, Gomariz RP, et al. Vasoactive intestinal peptide in the immune system: potential therapeutic role in inflammatory and autoimmune diseases. J Mol Med 2002; 80: 16-24.
-
(2002)
J Mol Med
, vol.80
, pp. 16-24
-
-
Delgado, M.1
Abad, C.2
Martinez, C.3
Juarranz, Y.4
Arranz, A.5
Gomariz, R.P.6
-
166
-
-
0035041433
-
Immunology of VIP: A review and therapeutical perspectives
-
Gomariz RP, Martinez C, Abad C, Leceta J, Delgado M. Immunology of VIP: a review and therapeutical perspectives. Curr Pharm Des 2001; 7: 89-111.
-
(2001)
Curr Pharm Des
, vol.7
, pp. 89-111
-
-
Gomariz, R.P.1
Martinez, C.2
Abad, C.3
Leceta, J.4
Delgado, M.5
-
167
-
-
2642566879
-
The significance of vasoactive intestinal peptide in immunomodulation
-
Delgado M, Pozo D, Ganea D. The significance of vasoactive intestinal peptide in immunomodulation. Pharmacol Rev 2004; 56: 249-290
-
(2004)
Pharmacol Rev
, vol.56
, pp. 249-290
-
-
Delgado, M.1
Pozo, D.2
Ganea, D.3
-
168
-
-
0035033922
-
Vasoactive intestinal peptide prevents experimental arthritis by downregulating both autoimmune and inflammatory components of the disease
-
Delgado M, Abad C, Martinez C, Leceta J, Gomariz RP. Vasoactive intestinal peptide prevents experimental arthritis by downregulating both autoimmune and inflammatory components of the disease. Nat Med 2001; 7: 563-568
-
(2001)
Nat Med
, vol.7
, pp. 563-568
-
-
Delgado, M.1
Abad, C.2
Martinez, C.3
Leceta, J.4
Gomariz, R.P.5
-
169
-
-
0037379777
-
Therapeutic effects of vasoactive intestinal peptide in the trinitrobenzene sulfonic acid model of Crohn's disease
-
Abad C, Martínez C, Juarranz MG, Arranz A, Leceta J, Delgado M, et al. Therapeutic effects of vasoactive intestinal peptide in the trinitrobenzene sulfonic acid model of Crohn's disease. Gastroenterology 2003; 124: 961-971
-
(2003)
Gastroenterology
, vol.124
, pp. 961-971
-
-
Abad, C.1
Martínez, C.2
Juarranz, M.G.3
Arranz, A.4
Leceta, J.5
Delgado, M.6
-
170
-
-
33748983978
-
Vasoactive intestinal peptide suppressed experimental autoimmune encephalomyelitis by inhibiting T helper 1 responses
-
Li H, Mei Y, Wang Y, Xu L. Vasoactive intestinal peptide suppressed experimental autoimmune encephalomyelitis by inhibiting T helper 1 responses. J Clin Immunol 2006; 26: 430-437
-
(2006)
J Clin Immunol
, vol.26
, pp. 430-437
-
-
Li, H.1
Mei, Y.2
Wang, Y.3
Xu, L.4
-
171
-
-
31144475640
-
Effect of human vasoactive intestinal peptide gene transfer in a murine model of Sjogren's syndrome
-
Lodde BM, Mishiba F, Wang J, Cotrim AP, Afiore S, Tak PP, et al. Effect of human vasoactive intestinal peptide gene transfer in a murine model of Sjogren's syndrome. Ann Rheum Dis 2006; 65: 195-200.
-
(2006)
Ann Rheum Dis
, vol.65
, pp. 195-200
-
-
Lodde, B.M.1
Mishiba, F.2
Wang, J.3
Cotrim, A.P.4
Afiore, S.5
Tak, P.P.6
-
172
-
-
33746429486
-
VIP and tolerance induction in autoimmunity
-
Rosignoli F, Torroba M, Juarranz Y, García-Gómez M, Martínez C, Gomariz RP, et al. VIP and tolerance induction in autoimmunity. Ann NY Acad Sci USA 2006; 1070: 525-530
-
(2006)
Ann NY Acad Sci USA
, vol.1070
, pp. 525-530
-
-
Rosignoli, F.1
Torroba, M.2
Juarranz, Y.3
García-Gómez, M.4
Martínez, C.5
Gomariz, R.P.6
-
173
-
-
33845900208
-
Regulation of immune tolerance by anti-inflammatory neuropeptides
-
Gonzalez-Rey E, Chorny A, Delgado M. Regulation of immune tolerance by anti-inflammatory neuropeptides. Nat Rev Immunol 2007; 7: 52-63.
-
(2007)
Nat Rev Immunol
, vol.7
, pp. 52-63
-
-
Gonzalez-Rey, E.1
Chorny, A.2
Delgado, M.3
-
174
-
-
34548396699
-
Regulation of TLR expression, a new perspective for the role of VIP in immunity
-
Gomariz RP, Arranz A, Juarranz Y, Gutierrez-Cañas I, García-Gómez M, Leceta J, et al. Regulation of TLR expression, a new perspective for the role of VIP in immunity. Peptides 2007; 28: 1825-1832
-
(2007)
Peptides
, vol.28
, pp. 1825-1832
-
-
Gomariz, R.P.1
Arranz, A.2
Juarranz, Y.3
Gutierrez-Cañas, I.4
García-Gómez, M.5
Leceta, J.6
-
175
-
-
22544473593
-
TLR7/8-mediated activation of human NK cells results in accessory cell-dependent IFN-gamma production
-
Hart OM, Athie-Morales V, O'Connor GM, Gardiner CM. TLR7/8-mediated activation of human NK cells results in accessory cell-dependent IFN-gamma production. J Immunol 2005; 175: 1636-1642
-
(2005)
J Immunol
, vol.175
, pp. 1636-1642
-
-
Hart, O.M.1
Athie-Morales, V.2
O'Connor, G.M.3
Gardiner, C.M.4
-
176
-
-
0037799912
-
Toll-like receptor-dependent production of IL-12p40 causes chronic enterocolitis in myeloid cell-specific Stat3-deficient mice
-
Kobayashi M, Kweon MN, Kuwata H, Schreiber RD, Kiyono H, Takeda K, et al. Toll-like receptor-dependent production of IL-12p40 causes chronic enterocolitis in myeloid cell-specific Stat3-deficient mice. J Clin Invest 2003; 111: 1297-1308
-
(2003)
J Clin Invest
, vol.111
, pp. 1297-1308
-
-
Kobayashi, M.1
Kweon, M.N.2
Kuwata, H.3
Schreiber, R.D.4
Kiyono, H.5
Takeda, K.6
-
177
-
-
0028861975
-
Antibodies to interleukin 12 abrogate established experimental colitis in mice
-
Neurath MF, Fuss I, Kelsall BL, Stuber E, Strober W. Antibodies to interleukin 12 abrogate established experimental colitis in mice. J Exp Med 1995; 182: 1281-1290
-
(1995)
J Exp Med
, vol.182
, pp. 1281-1290
-
-
Neurath, M.F.1
Fuss, I.2
Kelsall, B.L.3
Stuber, E.4
Strober, W.5
-
178
-
-
0036284984
-
The role of Th1/Th2 polarization in mucosal immunity
-
Neurath MF, Finotto S, Glimcher LH. The role of Th1/Th2 polarization in mucosal immunity. Nat Med 2002; 8: 567-573
-
(2002)
Nat Med
, vol.8
, pp. 567-573
-
-
Neurath, M.F.1
Finotto, S.2
Glimcher, L.H.3
-
179
-
-
23044442144
-
Time-course of toll-like receptors 2 and 4 in inflammatory bowel disease and homeostatic effect of VIP
-
Gomariz RP, Arranz A, Abad C, Torroba M, Martínez C, Rosignoli F, et al. Time-course of toll-like receptors 2 and 4 in inflammatory bowel disease and homeostatic effect of VIP. J Leukoc Biol 2005; 78: 491-502.
-
(2005)
J Leukoc Biol
, vol.78
, pp. 491-502
-
-
Gomariz, R.P.1
Arranz, A.2
Abad, C.3
Torroba, M.4
Martínez, C.5
Rosignoli, F.6
-
180
-
-
33746441017
-
Effect of VIP on TLR2 and TLR4 expression in lymph node immune cells during TNBS-induced colitis
-
Arranz A, Abad C, Juarranz Y, Torroba M, Rosignoli F, Leceta J, et al. Effect of VIP on TLR2 and TLR4 expression in lymph node immune cells during TNBS-induced colitis. Ann NY Acad Sci 2006; 1070: 129-134
-
(2006)
Ann NY Acad Sci
, vol.1070
, pp. 129-134
-
-
Arranz, A.1
Abad, C.2
Juarranz, Y.3
Torroba, M.4
Rosignoli, F.5
Leceta, J.6
-
181
-
-
48349087208
-
Vasoactive intestinal peptide as a healing mediator in Crohn' disease
-
Arranz A, Abad C, Juarranz Y, Leceta J, Martínez C, Gomariz RP. Vasoactive intestinal peptide as a healing mediator in Crohn' disease. Neuroimmunomodulation 2008; 15: 46-53.
-
(2008)
Neuroimmunomodulation
, vol.15
, pp. 46-53
-
-
Arranz, A.1
Abad, C.2
Juarranz, Y.3
Leceta, J.4
Martínez, C.5
Gomariz, R.P.6
-
182
-
-
0035313049
-
NF-κB and STAT 5 play important roles in the regulation of mouse tolllike receptor 2 gene expression
-
Musikacharoen T, Matsuguchi T, Kikuchi T, Yoshikai Y. NF-κB and STAT 5 play important roles in the regulation of mouse tolllike receptor 2 gene expression. J Immunol 2001; 166: 4516-4524
-
(2001)
J Immunol
, vol.166
, pp. 4516-4524
-
-
Musikacharoen, T.1
Matsuguchi, T.2
Kikuchi, T.3
Yoshikai, Y.4
-
183
-
-
0032553421
-
Vasoactive intestinal peptide and pituitary adenylate cyclase-activating polypeptide inhibit tumor necrosis factor α transcriptional activation by regulating nuclear factor-κB and cAMP response element-binding protein/c-Jun
-
Delgado M, Muñoz-Elias EJ, Kan Y, Gozes I, Fridkin M, Brenneman DE, et al. Vasoactive intestinal peptide and pituitary adenylate cyclase-activating polypeptide inhibit tumor necrosis factor α transcriptional activation by regulating nuclear factor-κB and cAMP response element-binding protein/c-Jun. J Biol Chem 1998; 273: 31427-31436
-
(1998)
J Biol Chem
, vol.273
, pp. 31427-31436
-
-
Delgado, M.1
Muñoz-Elias, E.J.2
Kan, Y.3
Gozes, I.4
Fridkin, M.5
Brenneman, D.E.6
-
184
-
-
33645733084
-
Protective effect of vasoactive intestinal peptide on bone destruction in the collagen-induced arthritis model of rheumatoid arthritis
-
Juarranz Y, Abad C, Martínez C, Arranz A, Gutierrez-Cañas I, Rosignoli F, et al. Protective effect of vasoactive intestinal peptide on bone destruction in the collagen-induced arthritis model of rheumatoid arthritis. Arthritis Res Ther 2005; 7: 1034-1045
-
(2005)
Arthritis Res Ther
, vol.7
, pp. 1034-1045
-
-
Juarranz, Y.1
Abad, C.2
Martínez, C.3
Arranz, A.4
Gutierrez-Cañas, I.5
Rosignoli, F.6
-
185
-
-
43049113127
-
VIP balances innate and adaptive immune responses induced by specific stimulation of TLR2 and TLR4
-
Arranz A, Juarranz Y, Leceta J, Gomariz RP, Martínez C. VIP balances innate and adaptive immune responses induced by specific stimulation of TLR2 and TLR4. Peptides 2008; 29: 948-956
-
(2008)
Peptides
, vol.29
, pp. 948-956
-
-
Arranz, A.1
Juarranz, Y.2
Leceta, J.3
Gomariz, R.P.4
Martínez, C.5
-
186
-
-
0034773576
-
Tissue cytokine and chemokine expression in inflammatory bowel disease
-
McCormack G, Moriarty D, O'Donoghue DP, McCormick PA, Sheahan K, Baird AW. Tissue cytokine and chemokine expression in inflammatory bowel disease. Inflamm Res 2001; 50: 491-495
-
(2001)
Inflamm Res
, vol.50
, pp. 491-495
-
-
McCormack, G.1
Moriarty, D.2
O'Donoghue, D.P.3
McCormick, P.A.4
Sheahan, K.5
Baird, A.W.6
-
187
-
-
58249085293
-
Toll-like receptor-potential drug targets in infectious disease
-
Erard F, Ryffel B. Toll-like receptor-potential drug targets in infectious disease. Infect Disord Drug Targets 2008; 8: 221-231
-
(2008)
Infect Disord Drug Targets
, vol.8
, pp. 221-231
-
-
Erard, F.1
Ryffel, B.2
-
188
-
-
23044454798
-
Expression and function of toll-like receptor on T cells
-
Xu D, Komai-Koma M, Liew FY. Expression and function of toll-like receptor on T cells. Cell Immunol 2005; 233: 85-89
-
(2005)
Cell Immunol
, vol.233
, pp. 85-89
-
-
Xu, D.1
Komai-Koma, M.2
Liew, F.Y.3
-
189
-
-
33846123950
-
Expression and function of toll-like receptors in T lymphocytes
-
Kabelitz D. Expression and function of toll-like receptors in T lymphocytes. Curr Opin Immunol 2007; 19: 39-45.
-
(2007)
Curr Opin Immunol
, vol.19
, pp. 39-45
-
-
Kabelitz, D.1
-
190
-
-
33646487278
-
Toll-like receptor 2 signaling modulates the functions of CD4+CD25+ regulatory T cells
-
Liu H, Komai-Koma M, Xu D, Liew FY. Toll-like receptor 2 signaling modulates the functions of CD4+CD25+ regulatory T cells. Proc Natl Acad Sci USA 2006; 103: 7048-7053
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 7048-7053
-
-
Liu, H.1
Komai-Koma, M.2
Xu, D.3
Liew, F.Y.4
-
191
-
-
0037450804
-
Regulatory T cells selectively express toll-like receptors and are activated by lipopolysaccharide
-
Caramalho I, Lopes-Carvalho T, Ostler D, Zelenay S, Haury M, Demengeot J. Regulatory T cells selectively express toll-like receptors and are activated by lipopolysaccharide. J Exp Med 2003; 197: 403-411
-
(2003)
J Exp Med
, vol.197
, pp. 403-411
-
-
Caramalho, I.1
Lopes-Carvalho, T.2
Ostler, D.3
Zelenay, S.4
Haury, M.5
Demengeot, J.6
-
192
-
-
38349051040
-
Vasoactive intestinal peptide rescues cultured rat myenteric neurons from lipopolysaccharide induced cell death
-
Arciszewski MB, Sand E, Ekblad E. Vasoactive intestinal peptide rescues cultured rat myenteric neurons from lipopolysaccharide induced cell death. Regul Pept 2008; 146: 218-223
-
(2008)
Regul Pept
, vol.146
, pp. 218-223
-
-
Arciszewski, M.B.1
Sand, E.2
Ekblad, E.3
-
193
-
-
2342534336
-
Role of vasoactive intestinal peptide and inflammatory mediators in enteric neuronal plasticity
-
Ekblad E, Bauer AJ. Role of vasoactive intestinal peptide and inflammatory mediators in enteric neuronal plasticity. Neurogastroenterol Motil 2004; 16: 123-128
-
(2004)
Neurogastroenterol Motil
, vol.16
, pp. 123-128
-
-
Ekblad, E.1
Bauer, A.J.2
-
194
-
-
0038184173
-
Vasoactive intestinal peptide and nitric oxide promote survival of adult rat myenteric neurons in culture
-
Sandgren K, Lin Z, Fex-Svenningsen A, Ekblad E. Vasoactive intestinal peptide and nitric oxide promote survival of adult rat myenteric neurons in culture. J Neurosci Res 2003; 72: 592-602.
-
(2003)
J Neurosci Res
, vol.72
, pp. 592-602
-
-
Sandgren, K.1
Lin, Z.2
Fex-Svenningsen, A.3
Ekblad, E.4
-
195
-
-
0034129883
-
A new concept in the pharmacology of neuroprotection
-
Gozes I, Brenneman DE. A new concept in the pharmacology of neuroprotection. J Mol Neurosci 2000; 14: 61-68
-
(2000)
J Mol Neurosci
, vol.14
, pp. 61-68
-
-
Gozes, I.1
Brenneman, D.E.2
-
196
-
-
0031861807
-
Enteric neuronal plasticity and a reduced number of interstitial cells of Cajal in hypertrophic rat ileum
-
Ekblad E, Sjuve R, Arner A, Sundler F. Enteric neuronal plasticity and a reduced number of interstitial cells of Cajal in hypertrophic rat ileum. Gut 1998; 42: 836-844
-
(1998)
Gut
, vol.42
, pp. 836-844
-
-
Ekblad, E.1
Sjuve, R.2
Arner, A.3
Sundler, F.4
-
197
-
-
23944452404
-
Lipopolysaccharide induces cell death in cultured porcine myenteric neurons
-
Arciszewski MB, Pierzynowski S, Ekblad E. Lipopolysaccharide induces cell death in cultured porcine myenteric neurons. Dig Dis Sci 2005; 50: 1661-1668
-
(2005)
Dig Dis Sci
, vol.50
, pp. 1661-1668
-
-
Arciszewski, M.B.1
Pierzynowski, S.2
Ekblad, E.3
-
198
-
-
41849087644
-
Vasoactive intestinal peptide suppresses toll-like receptor 4 expression in macrophages via Akt1 reducing their responsiveness to lipopolysaccharide
-
Arranz A, Androulidaki A, Zacharioudaki V, Martínez C, Margioris AN, Gomariz RP, et al. Vasoactive intestinal peptide suppresses toll-like receptor 4 expression in macrophages via Akt1 reducing their responsiveness to lipopolysaccharide. Mol Immunol 2008; 45: 2970-2980
-
(2008)
Mol Immunol
, vol.45
, pp. 2970-2980
-
-
Arranz, A.1
Androulidaki, A.2
Zacharioudaki, V.3
Martínez, C.4
Margioris, A.N.5
Gomariz, R.P.6
-
199
-
-
17644399823
-
Critical role for Ets, AP-1 and GATA-like transcription factors in regulating mouse Toll-like receptor 4 (Tlr4) gene expression
-
Roger T, Miconnet I, Schiesser AL, Kai H, Miyake K, Calandra T. Critical role for Ets, AP-1 and GATA-like transcription factors in regulating mouse Toll-like receptor 4 (Tlr4) gene expression. Biochem J 2005; 387: 355-365
-
(2005)
Biochem J
, vol.387
, pp. 355-365
-
-
Roger, T.1
Miconnet, I.2
Schiesser, A.L.3
Kai, H.4
Miyake, K.5
Calandra, T.6
-
200
-
-
0037199972
-
The phosphatidylinositol 3-kinase-Akt pathway limits lipopolysaccharide activation of signaling pathways and expression of inflammatory mediators in human monocytic cells
-
Guha M, Mackman N. The phosphatidylinositol 3-kinase-Akt pathway limits lipopolysaccharide activation of signaling pathways and expression of inflammatory mediators in human monocytic cells. J Biol Chem 2002; 277: 32124-32132
-
(2002)
J Biol Chem
, vol.277
, pp. 32124-32132
-
-
Guha, M.1
Mackman, N.2
-
201
-
-
20244384395
-
Cutting edge: Endotoxin tolerance in mouse peritoneal macrophages correlates with downregulation of surface toll-like receptor 4 expression
-
Nomura F, Akashi S, Sakao Y, Sato S, Kawai T, Matsumoto M, et al. Cutting edge: endotoxin tolerance in mouse peritoneal macrophages correlates with downregulation of surface toll-like receptor 4 expression. J Immunol 2000; 164: 3476-3479
-
(2000)
J Immunol
, vol.164
, pp. 3476-3479
-
-
Nomura, F.1
Akashi, S.2
Sakao, Y.3
Sato, S.4
Kawai, T.5
Matsumoto, M.6
-
202
-
-
0036159842
-
Endotoxin tolerance: A review
-
West MA, Heagy W. Endotoxin tolerance: a review. Crit Care Med 2002; 30: S64-S73.
-
(2002)
Crit Care Med
, vol.30
-
-
West, M.A.1
Heagy, W.2
-
203
-
-
77449128059
-
Toll-like receptor stimulation differentially regulates vasoactive intestinal peptide type 2 receptor in macrophages
-
January 16; doi. 10.111/j1582-4934.2008.00662
-
Herrera JL, Gonzalez-Rey E, Fernández-Montesinos R, Quintana FJ, Najmanovich R, Pozo D. Toll-like receptor stimulation differentially regulates vasoactive intestinal peptide type 2 receptor in macrophages. J Cell Mol Med 2009; January 16; doi. 10.111/j1582-4934.2008.00662.
-
(2009)
J Cell Mol Med
-
-
Herrera, J.L.1
Gonzalez-Rey, E.2
Fernández-Montesinos, R.3
Quintana, F.J.4
Najmanovich, R.5
Pozo, D.6
-
204
-
-
33646205361
-
VIP down-regulates TLR4 expression and TLR4-mediated chemokine production in human rheumatoid synovial fibroblasts
-
Gutierrez-Cañas I, Juarranz Y, Santiago B, Arranz A, Martínez C, Galindo M, et al. VIP down-regulates TLR4 expression and TLR4-mediated chemokine production in human rheumatoid synovial fibroblasts. Rheumatology 2006; 45: 527-532
-
(2006)
Rheumatology
, vol.45
, pp. 527-532
-
-
Gutierrez-Cañas, I.1
Juarranz, Y.2
Santiago, B.3
Arranz, A.4
Martínez, C.5
Galindo, M.6
-
205
-
-
23044494509
-
The role of Toll-like receptor signalling in the pathogenesis of arthritis
-
Brentano F, Kyburz D, Schorr O, Gay R, Gay S. The role of Toll-like receptor signalling in the pathogenesis of arthritis. Cell Immunol 2005; 233: 90-96
-
(2005)
Cell Immunol
, vol.233
, pp. 90-96
-
-
Brentano, F.1
Kyburz, D.2
Schorr, O.3
Gay, R.4
Gay, S.5
-
206
-
-
10444278132
-
Expression of toll-like receptors 2 and 4 in rheumatoid synovial tissue and regulation by proinflammatory cytokines interleukin-12 and interleukin-18 via interferon-γ
-
Radstake TR, Roelofs MF, Jenniskens YM, Oppers-Walgreen B, van Riel RL, Barrera P, et al. Expression of toll-like receptors 2 and 4 in rheumatoid synovial tissue and regulation by proinflammatory cytokines interleukin-12 and interleukin-18 via interferon-γ. Arthritis Rheum 2004; 50: 3856-3865
-
(2004)
Arthritis Rheum
, vol.50
, pp. 3856-3865
-
-
Radstake, T.R.1
Roelofs, M.F.2
Jenniskens, Y.M.3
Oppers-Walgreen, B.4
Van Riel, R.L.5
Barrera, P.6
-
207
-
-
0037333990
-
Bacterial peptidoglycans but not CpG oligodeoxynucleotides activate fibroblasts by toll-like receptor signaling
-
Kyburz D, Rethage J, Seibl R, Lauener R, Gay RE, Carson DA, et al. Bacterial peptidoglycans but not CpG oligodeoxynucleotides activate fibroblasts by toll-like receptor signaling. Arthritis Rheum 2003; 48: 642-650
-
(2003)
Arthritis Rheum
, vol.48
, pp. 642-650
-
-
Kyburz, D.1
Rethage, J.2
Seibl, R.3
Lauener, R.4
Gay, R.E.5
Carson, D.A.6
-
208
-
-
2342447988
-
Synergistic induction of CXCL9 and CXCL11 by toll-like receptor ligands and interferon-γ in fibroblasts correlates with elevated levels of CXCR3 in septic arthritis synovial fluids
-
Proost P, Verpoest S, Van de Borne K, Schutyser E, Struyf S, Put W, et al. Synergistic induction of CXCL9 and CXCL11 by toll-like receptor ligands and interferon-γ in fibroblasts correlates with elevated levels of CXCR3 in septic arthritis synovial fluids. J Leukoc Biol 2004; 75: 777-784
-
(2004)
J Leukoc Biol
, vol.75
, pp. 777-784
-
-
Proost, P.1
Verpoest, S.2
Van De Borne, K.3
Schutyser, E.4
Struyf, S.5
Put, W.6
-
209
-
-
0037378466
-
Expression and regulation of toll-like receptor 2 in rheumatoid arthritis synovium
-
Seibl R, Birchler T, Loeliger S, Hossle JP, Gay RE, Saurenmann T, et al. Expression and regulation of toll-like receptor 2 in rheumatoid arthritis synovium. Am J Pathol 2003; 162: 1221-1227
-
(2003)
Am J Pathol
, vol.162
, pp. 1221-1227
-
-
Seibl, R.1
Birchler, T.2
Loeliger, S.3
Hossle, J.P.4
Gay, R.E.5
Saurenmann, T.6
-
210
-
-
12444320979
-
A chemokine-dependent stromal induction mechanisms for aberrant lymphocyte accumulation and compromised lymphatic return in rheumatoid arthritis
-
Burman A, Haworth O, Hardie DL, Amft EN, Siewrt C, Jackson DG, et al. A chemokine-dependent stromal induction mechanisms for aberrant lymphocyte accumulation and compromised lymphatic return in rheumatoid arthritis. J Immunol 2005; 174: 1693-1700
-
(2005)
J Immunol
, vol.174
, pp. 1693-1700
-
-
Burman, A.1
Haworth, O.2
Hardie, D.L.3
Amft, E.N.4
Siewrt, C.5
Jackson, D.G.6
-
211
-
-
11144353770
-
Vasoactive intestinal peptide modulates pro-inflammatory mediator synthesis in osteoarthritic and rheuma-toid synovial cells
-
Juarranz MG, Santiago B, Torroba M, Gutierrez-Cañas I, Palao G, Galindo M, et al. Vasoactive intestinal peptide modulates pro-inflammatory mediator synthesis in osteoarthritic and rheuma-toid synovial cells. Rheumatology 2004; 43: 416-422
-
(2004)
Rheumatology
, vol.43
, pp. 416-422
-
-
Juarranz, M.G.1
Santiago, B.2
Torroba, M.3
Gutierrez-Cañas, I.4
Palao, G.5
Galindo, M.6
-
212
-
-
43449120111
-
VIP reverses the expression profiling of TLR4-stimulated signaling pathway in rheumatoid arthritis synovial fibroblasts
-
Arranz A, Gutierrez Cañas I, Carrión M, Juarranz Y, Pablos JL, Martínez C, et al. VIP reverses the expression profiling of TLR4-stimulated signaling pathway in rheumatoid arthritis synovial fibroblasts. Mol Immunol 2008; 45: 3065-3073
-
(2008)
Mol Immunol
, vol.45
, pp. 3065-3073
-
-
Arranz, A.1
Gutierrez Cañas, I.2
Carrión, M.3
Juarranz, Y.4
Pablos, J.L.5
Martínez, C.6
-
213
-
-
0032832033
-
Shedding of membrane-bound CD14 from lipopolysaccharide-stimulated macrophages by vasoactive intestinal peptide and pituitary adenylate cyclase activating polypeptide
-
Delgado M, Leceta J, Abad C, Martínez C, Ganea D, Gomariz RP. Shedding of membrane-bound CD14 from lipopolysaccharide-stimulated macrophages by vasoactive intestinal peptide and pituitary adenylate cyclase activating polypeptide. J Neuroimmunol 1999; 99: 61-71.
-
(1999)
J Neuroimmunol
, vol.99
, pp. 61-71
-
-
Delgado, M.1
Leceta, J.2
Abad, C.3
Martínez, C.4
Ganea, D.5
Gomariz, R.P.6
-
214
-
-
42449095809
-
Differential expression of vasoactive intestinal peptide and its functional receptors in human osteoarthritic and rheumatoid synovial fibroblasts
-
Juarranz Y, Gutierrez-Cañas I, Santiago B, Carrión M, Pablos JL, Gomariz RP. Differential expression of vasoactive intestinal peptide and its functional receptors in human osteoarthritic and rheumatoid synovial fibroblasts. Arthritis Rheum 2008; 58: 1086-1095
-
(2008)
Arthritis Rheum
, vol.58
, pp. 1086-1095
-
-
Juarranz, Y.1
Gutierrez-Cañas, I.2
Santiago, B.3
Carrión, M.4
Pablos, J.L.5
Gomariz, R.P.6
-
215
-
-
42449095810
-
Genetic association of vasoactive intestinal peptide receptor with rheumatoid arthritis: Altered expression and signal in immune cells
-
Delgado M, Robledo G, Rueda B, Varela N, O'Valle F, Hernández- Cortés P, et al. Genetic association of vasoactive intestinal peptide receptor with rheumatoid arthritis: altered expression and signal in immune cells. Arthritis Rheum 2008; 58: 1010-1019.
-
(2008)
Arthritis Rheum
, vol.58
, pp. 1010-1019
-
-
Delgado, M.1
Robledo, G.2
Rueda, B.3
Varela, N.4
O'Valle, F.5
Hernández- Cortés, P.6
-
216
-
-
33947643643
-
Vasoactive intestinal peptide inhibits up-regulation of human monocytes TLR2 and TLR4 by LPS and differentiation of monocytes to macrophages
-
Foster N, Lea SR, Preshaw PM, Taylor JJ. Vasoactive intestinal peptide inhibits up-regulation of human monocytes TLR2 and TLR4 by LPS and differentiation of monocytes to macrophages. J Leukoc Biol 2007; 81: 893-903.
-
(2007)
J Leukoc Biol
, vol.81
, pp. 893-903
-
-
Foster, N.1
Lea, S.R.2
Preshaw, P.M.3
Taylor, J.J.4
-
217
-
-
0036679732
-
Of mice and men: Species variation of toll-like receptor variation
-
Rehli M. Of mice and men: species variation of toll-like receptor variation. Trends Immunol 2002; 23: 375-378
-
(2002)
Trends Immunol
, vol.23
, pp. 375-378
-
-
Rehli, M.1
-
218
-
-
0034737660
-
PU.1 and interferon consensus sequence-binding protein regulate the myeloid expression of the human toll-like receptor 4 gene
-
Rehli M, Poltorak A, Schwarzfischer I, Krause SW, Andreesen R, Beutler B. PU.1 and interferon consensus sequence-binding protein regulate the myeloid expression of the human toll-like receptor 4 gene. J Biol Chem 2000; 275: 9773-9781
-
(2000)
J Biol Chem
, vol.275
, pp. 9773-9781
-
-
Rehli, M.1
Poltorak, A.2
Schwarzfischer, I.3
Krause, S.W.4
Andreesen, R.5
Beutler, B.6
-
219
-
-
0036604207
-
Transcriptional regulation of the human Toll-like receptor 2 gene in monocytes and macrophages
-
Haehnel V, Schwarzfischer I, Fenton MJ, Rehli M. Transcriptional regulation of the human Toll-like receptor 2 gene in monocytes and macrophages. J Immunol 2002; 168: 5629-5637
-
(2002)
J Immunol
, vol.168
, pp. 5629-5637
-
-
Haehnel, V.1
Schwarzfischer, I.2
Fenton, M.J.3
Rehli, M.4
-
220
-
-
42049097685
-
Role of toll-like receptors in immune responses to chlamydial infections
-
Joyee AG, Yang X. Role of toll-like receptors in immune responses to chlamydial infections. Curr Pharm Des 2008; 14(6): 593-600.
-
(2008)
Curr Pharm Des
, vol.14
, Issue.6
, pp. 593-600
-
-
Joyee, A.G.1
Yang, X.2
-
221
-
-
65649154649
-
Antiviral role of toll-like receptor-3 agonists against seasonal and avian influenza viruses
-
Wong JP, Christopher ME, Viswanathan S, Dai X, Salazar AM, Sun LQ, et al. Antiviral role of toll-like receptor-3 agonists against seasonal and avian influenza viruses. Curr Pharm Des 2009; 15(11): 1269-1274
-
(2009)
Curr Pharm Des
, vol.15
, Issue.11
, pp. 1269-1274
-
-
Wong, J.P.1
Christopher, M.E.2
Viswanathan, S.3
Dai, X.4
Salazar, A.M.5
Sun, L.Q.6
-
222
-
-
52949088659
-
Radiometal targeted tumor diagnosis and therapy with peptide hormones
-
Zwanziger D, Beck-Sickinger AG. Radiometal targeted tumor diagnosis and therapy with peptide hormones. Curr Pharm Des 2008; 14(24): 2385-2400
-
(2008)
Curr Pharm Des
, vol.14
, Issue.24
, pp. 2385-2400
-
-
Zwanziger, D.1
Beck-Sickinger, A.G.2
|