Vasoactive intestinal peptide and nitric oxide promote survival of adult rat myenteric neurons in culture

Journal of Neuroscience Research

Volumn 72, Issue 5, 2003, Pages 595-602

  Sandgren, Katarina ^a   Lin, Zhong ^a   Svenningsen, Åsa Fex ^b   Ekblad, Eva ^a,c  

^a LUND UNIVERSITY   (Sweden)

^b MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^c BMC F10   (Sweden)

Author keywords

Enteric nervous system; Neuronal plasticity; Neurotransmitter expression; Nitric oxide synthase

Indexed keywords

N ACETYL S NITROSOPENICILLAMINE; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; NITRIC OXIDE SYNTHASE INHIBITOR; VASOACTIVE INTESTINAL POLYPEPTIDE;

ANIMAL CELL; ARTICLE; CELL SURVIVAL; IMMUNOCYTOCHEMISTRY; MYENTERIC PLEXUS; NERVE CELL CULTURE; NERVE CELL PLASTICITY; NEUROTRANSMISSION; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALS; ANTIBODIES; CELL CULTURE TECHNIQUES; CELL DEATH; CELL SURVIVAL; CELLS, CULTURED; ENZYME INHIBITORS; FEMALE; IMMUNOHISTOCHEMISTRY; MYENTERIC PLEXUS; NEURONS; NITRIC OXIDE; NITRIC OXIDE DONORS; NITRIC OXIDE SYNTHASE; RATS; RATS, SPRAGUE-DAWLEY; UP-REGULATION; VASOACTIVE INTESTINAL PEPTIDE;

EID: 0038184173     PISSN: 03604012     EISSN: None     Source Type: Journal    
DOI: 10.1002/jnr.10612     Document Type: Article

References (53)

1. Ashur-Fabian O, Perl O, Lolling G, Fridkin, M, Gozes I. 1999. SNV, a lipophilic superactive VIP analog, acts through cGMP to promote neuronal survival. Peptides 20:629-633.
2. Ashur-Fabian O, Giladi E, Furman S, Steingart RA, Wollman Y, Fridkin M, Brenneman DE, Gozes I. 2001. Vasoactive intestinal peptide and related molecules induce nitrite accumulation in the extracellular milieu of rat cerebral cortical cultures. Neurosci Lett 307:167-170.
3. Badovinac V, Trajkovic V, Mostarica-Stojkovic M. 2000. Nitric oxide promotes growth and major histocompatibility complex-unrestricted cytotoxicity of interleukin-2-activated rat lymphocytes. Scand J Immunol 52:62-70.
4. Belai A, Burnstock G. 1999. Distribution and colocalization of nitric oxide synthase and calretinin in myenteric neurons of developing, aging, and Crohn's disease in human small intestine. Dig Dis Sci 8:1579-1587.
5. Belai A, Boulos PB, Robson T, Burnstock G. 1997. Neurochemical coding in the small intestine of patients with Crohn's disease. Gut 6:767-774.
6. Beltran B, Mathur A, Duchen MR, Erusalimsky JD, Moncada S. 2000. The effect of nitric oxide on cell respiration: A key to understanding its role in cell survival and death. Proc Natl Acad Sci USA 97:14602-14607.
7. Blennerhassett MG, Lourenssen S. 2000. Neural regulation of intestinal smooth muscle growth in vitro. Am J Gastrointest Liver Physiol 279: G511-G519.
8. Brenneman DE, Eiden LE. 1986. Vasoactive intestinal peptide and electrical activity influence neuronal survival. Proc Natl Acad Sci USA 4:1159-1162.
9. Brenneman DE, Hill JM, Glazner GW, Gozes I, Phillips TW. 1995. Interleukin-1 alpha and vasoactive intestinal peptide: enigmatic regulation of neuronal survival. Int J Dev Neurosci 13:187-200.
10. Chalazonitis A, Pham TD, Rothman TP, DiStefano PS, Bothwell M, Blair-Flynn J, Tessarollo L, Gershon MD. 2001. Neurotrophin-3 is required for the survival-differentiation of subsets of developing enteric neurons. J Neurosci 15:5620-5636.
11. Chiueh CC. 1999. Neuroprotective properties of nitric oxide. Ann N Y Acad Sci 890:301-311.
12. Ciani E, Baldinotti I, Contestabile A. 2001. Sustained, long-lasting inhibition of nitric oxide synthase aggravates the neural damage in some models of excitotoxic brain injury. Brain Res Bull 56:29-35.
13. Costa M, Furness JB, Pompolo S, Brookes SJ, Bornstein JC, Bredt DS, Snyder SH. 1992. Projections and chemical coding of neurons with immunoreactivity for NOS in the guinea-pig small intestine. Neurosci Lett 148:121-125.
14. Ekblad E, Alm P, Sundler F. 1994. Distribution, origin and projections of nitric oxide synthase containing neurons in gut and pancreas. Neuroscience 63:233-248.
15. Ekblad E, Mulder H, Sundler F. 1996. Vasoactive intestinal peptide expression in enteric neurons is upregulated by both colchicine and axotomy. Regul Pept 63:113-121.
16. Ekblad E, Sjuve R, Arner A, Sundler F. 1998. Enteric neuronal plasticity and a reduced number of interstitial cells of Cajal in hypertrophic rat ileum. Gut 45:236-245.
17. Ekblad E, Ekelund M, Sundler F. 1999. Neuronal plasticity in intestinal adaptation. In: Singer M, Krammer HJ, editors. Neurogastroenterology - Falk Symposium 112. Lancester, United Kingdom: Kluwer. p 33-43.
18. Ekelund KM, Ekblad E. 1999. Structural, neuronal, and functional adaptive changes in atrophic rat ileum. Gut 45:236-245.
19. Esplugues JV. 2002. NO as a signaling molecule in the nervous system. Br J Pharmacol 135:1079-1095.
20. Gershon MD. 1998. Neural injury, repair and adaptation in the GI tract. V. Genes, lineages and tissue interactions in the development of the enteric nervous system. Am J Physiol 275:G869-G873.
21. Gozes I, Brenneman DE. 1993. Neuropeptides as growth and differentiation factors in general and VIP in particular. J Mol Neurosci 4:1-9.
22. Gozes I, Brenneman DE. 2000. A new concept in the pharmacology of neuroprotection. J Mol Neurosci 14:61-68.
23. Gressens P, Hill JM, Gozes I, Fridkin M, Brenneman DE. 1993. Growth factor function of vasoactive intestinal peptide in whole cultured mouse embryos. Nature 362:155-158.
24. Hanani M, Xia Y, Wood JD. 1994. Myenteric ganglia from the adult guinea-pig small intestine in tissue culture. Neurogastroenterol Motil 6:103-118.
25. Hanani M, Francke M, Härtig W, Grosche J, Reichenbach A, Pannicke T. 2000. Patch-clamp study of neurons and glial cells in isolated myenteric ganglia. Am J Physiol Gastrointest Liver Physiol 278:G644-G651.
26. Höckerfelt U, Henriksson R, Franzen L, Norrgard O, Forsgren S. 1999. Irradiation induces marked immunohistochemical expression of vasoactive intestinal peptide in colonic mucosa of man. Dig Dis Sci 44:393-401.
27. Höckerfelt U, Franzen L, Kjorell U, Forsgren S. 2000. Parallel increase in substance P and VIP in rat duodenum in response to irradiation. Peptides 21:271-281.
28. Jaeger CB. 1995. Isolation of enteric ganglia from the myenteric plexus of adult rats. J Neural Transplant Plast 5:223-232.
29. Jessen KR, Saffrey MJ, Baluk P, Hanani M, Burnstock G. 1983. The enteric nervous system in tissue culture. III. Studies on neuronal survival and the retention of biochemical and morphological differentiation. Brain Res 262:49-62.
30. Klimaschewski L. 1997. VIP - a 'very important peptide' in the sympathetic nervous system? Anat Embryol 196:269-277.
31. Korman LY, Nylen ES, Finan TM, Linnoila RI, Becker KL. 1988. Primary culture of the enteric nervous system from neonatal hamster intestine. Selection of vasoactive intestinal polypeptide-containing neurons. Gastroenterology 95:1003-1010.
32. Kurjak M, Fritsch R, Saur D, Schudziarra V, Allescher HD. 2001. Functional coupling between nitric oxide synthesis and VIP release within enteric nerve terminals of the rat: involvement of protein kinase G and phosphodiesterase 5. J Physiol 534:827-836.
33. Lin Z, Gao N, Hu HZ, Lui S, Gao C, Kim G, Ren J, Xia Y, Peck OC, Wood JD. 2002. Immunoreactivity of Hu proteins facilitates identification of myenteric neurons in guinea-pig small intestine. Neurogastroenterol Mot 14:197-204.
34. Lipton SA. 1999. Neuronal protection and destruction by NO. Cell Death Differ 6:943-951.
35. Matsumoto SG. 1994. Neuronal differentiation in cultures of murine neural crest. I. Neurotransmitter expression. Brain Res Dev Brain Res 83:1-16.
36. Mohney RP, Zigmond RE. 1998. Vasoactive intestinal peptide enhances its own expression in sympathetic neurons after injury. J Neurosci 18:5285-5293.
37. Moncada S, Palmer RMJ, Higgs EA. 1991. Nitric oxide: physiology, pathology and pharmacology. Pharmacol Rev 443:109-142.
38. Murthy KS, Grider JR, Jin JG, Makhlouf GM. 1996. Interplay of VIP and nitric oxide in the regulation of neuromuscular activity in the gut. Ann N Y Acad Sci 805:355-362.
39. Nishi R, Willard AL. 1985. Neurons dissociated from rat myenteric plexus retain differentiated properties when grown in cell culture. I. Morphological properties and immunocytochemical localization of transmitter candidates. Neuroscience 16:187-199.
40. Pichel JG, Shen L, Sheng HZ, Granholm AC, Drago J, Grinberg A, Lee EJ, Huang SP, Saarma M, Hoffer BJ, Westphal H. 1996. Defects in enteric innervation and kidney development in mice lacking GDNF. Nature 382:73-76.
41. Reinshagen M, Rohm H, Steinkamp M, Lieb K, Geerling I, von Herbay A, Flämig G, Eysselein VE, Adler G. 2000. Protective role of neurotrophins in experimental inflammation of the rat gut. Gastroenterology 119:368-376.
42. Saffrey MJ, Burnstock G. 1994. Growth factors and the development and plasticity of the enteric nervous system. J Auton Nerv Sys 49:183-196.
43. Saffrey MJ, Wardhaugh T, Walker T, Daisley J, Silva AT. 2000. Trophic actions of neurotrophin-3 on postnatal rat myenteric neurons in vitro. Neuroscience Lett 278:133-136.
44. Sandgren K, Larsson LT, Ekblad E. 2002. Widespread changes in neurotransmitter expression and number of enteric neurons and interstitial cells of Cajal in lethal spotted mice. Dig Dis Sci 47:1049-1064.
45. Schäfer KH, Mestres P. 1997. Human newborn and adult myenteric plexus grows in different patterns. Cell Mol Biol 43:1171-1180.
46. Schäfer KH, Mestres P. 1999. The GDNF-induced neurite outgrowth and neuronal survival in dissociated myenteric plexus cultures of the rat small intestine decreases postnatally. Exp Brain Res 125:447-452.
47. Schäfer KH, Mestres P. 2000. Reaggregation of rat dissociated myenteric plexus in extracellular matrix gels. Dig Dis Sci 45:1631-1638.
48. Schneider J, Jehle EC, Starlinger MJ, Neunlist M, Michel K, Hoppe S, Schemann M. 2001. Neurotransmitter coding of enteric neurones in the submucous plexus is changed in non-inflamed rectum of patients with Crohn's disease. Neurogastroenterol Motil 13:255-264.
49. Schulte-Bockholt A, Fink JG, Meier DA, Otterson MF, Telford GL, Hopp K, Koch TR. 1995. Expression of mRNA for vasoactive intestinal peptide in normal human colon and during inflammation. Mol Cell Biochem 142:1-7.
50. Srinivasan S, Wiley JW. 2000. New insights into neural injury, repair, and adaptation in visceral afferents and the enteric nervous system. Curr Opin Gastroenterol 16:78-82.
51. 2+ concentration changes in cultured myenteric neurons. Neurogastroenterol Motil 12:117-124.
52. Wood JD, Alpers DH, Andrews PLR. 1999. Fundamentals of neurogastroenterology. Gut 45(Suppl II):II6-II16.
53. Zigmond RE. 2000. Neuropeptide action in sympathetic ganglia: evidence for distinct functions in intact and axotomized ganglia. Ann N Y Acad Sci 921:103-108.