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Volumn 2, Issue 3, 2004, Pages 219-274

Cancer gene therapy - Current status in the clinics

Author keywords

Cancer; Clinical trials; Gene therapy

Indexed keywords

ADENOVIRUS VECTOR; ANTINEOPLASTIC AGENT; ANTISENSE OLIGONUCLEOTIDE; BETA 2 MICROGLOBULIN; CISPLATIN; E1A PROTEIN; FLUOROURACIL; HERPES SIMPLEX VIRUS THYMIDINE KINASE; HLA B7 ANTIGEN; INTERLEUKIN 2; ONYX 015; PROTEIN P53; RETROVIRUS VECTOR; UNCLASSIFIED DRUG; VIRUS PROTEIN;

EID: 7044267227     PISSN: 13889532     EISSN: None     Source Type: Journal    
DOI: 10.1163/1568558042457488     Document Type: Review
Times cited : (3)

References (333)
  • 1
    • 0029086344 scopus 로고
    • Intratumoral injection of an adenovirus expressing interleukin 2 induces regression and immunity in a murine breast cancer model
    • Addison, C.L., Braciak, T., Ralston, R., Muller, W.J., Gauldie, J. and Graham, F.L. (1995). Intratumoral injection of an adenovirus expressing interleukin 2 induces regression and immunity in a murine breast cancer model. Proc. Natl. Acad. Sci. USA, 92: 8522-8526.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 8522-8526
    • Addison, C.L.1    Braciak, T.2    Ralston, R.3    Muller, W.J.4    Gauldie, J.5    Graham, F.L.6
  • 3
    • 0034186366 scopus 로고    scopus 로고
    • Prodrug activation enzymes in cancer gene therapy
    • Aghi, M., Hochberg, F. and Breakefield, X.O. (2000). Prodrug activation enzymes in cancer gene therapy. J. Gene Med., 2: 148-164.
    • (2000) J. Gene Med. , vol.2 , pp. 148-164
    • Aghi, M.1    Hochberg, F.2    Breakefield, X.O.3
  • 4
    • 0028951290 scopus 로고
    • High incidence of p53 alterations (mutation, deletion, overexpression) in head and neck primary tumors and metastases; absence of correlation with clinical outcome. Frequent protein overexpression in normal epithelium and in early non-invasive lesions
    • Ahomadegbe, J.C., Barrois, M., Fogel, S., Le Bihan, M.L., Douc-Rasy, S., Duvillard, P., Armand, J.P. and Riou, G. (1995). High incidence of p53 alterations (mutation, deletion, overexpression) in head and neck primary tumors and metastases; absence of correlation with clinical outcome. Frequent protein overexpression in normal epithelium and in early non-invasive lesions. Oncogene, 10: 1217-1227.
    • (1995) Oncogene , vol.10 , pp. 1217-1227
    • Ahomadegbe, J.C.1    Barrois, M.2    Fogel, S.3    Le Bihan, M.L.4    Douc-Rasy, S.5    Duvillard, P.6    Armand, J.P.7    Riou, G.8
  • 6
    • 0029055960 scopus 로고
    • Current approach to malignant mesothelioma of the pleura
    • Aisner, J. (1995). Current approach to malignant mesothelioma of the pleura. Chest, 107: 332S-344S.
    • (1995) Chest , vol.107
    • Aisner, J.1
  • 7
    • 0032485487 scopus 로고    scopus 로고
    • Dendritic cells acquire antigen from apoptotic cells and induce class I-restricted CTLs
    • Albert, M.L., Sauter, B. and Bhardwaj, N. (1998). Dendritic cells acquire antigen from apoptotic cells and induce class I-restricted CTLs. Nature, 392: 86-89.
    • (1998) Nature , vol.392 , pp. 86-89
    • Albert, M.L.1    Sauter, B.2    Bhardwaj, N.3
  • 8
    • 0033926002 scopus 로고    scopus 로고
    • Replicative adenoviruses for cancer therapy
    • Alemany, R., Balague, C. and Curiel, D.T. (2000). Replicative adenoviruses for cancer therapy. Nat. Biotechnol., 18: 723-727.
    • (2000) Nat. Biotechnol. , vol.18 , pp. 723-727
    • Alemany, R.1    Balague, C.2    Curiel, D.T.3
  • 11
  • 12
    • 0024276438 scopus 로고
    • First human gene transfer trial
    • Antoine, F.S. (1988). First human gene transfer trial. J. Natl. Cancer Inst., 80: 1364-1365.
    • (1988) J. Natl. Cancer Inst. , vol.80 , pp. 1364-1365
    • Antoine, F.S.1
  • 13
    • 0025806563 scopus 로고
    • Murine tumor cells transduced with the gene for tumor necrosis factor-alpha. Evidence for paracrine immune effects of tumor necrosis factor against tumors
    • Asher, A.L., Mule, J.J., Kasid, A., Restifo, N.P., Salo, J.C., Reichert, C.M., Jaffe, G., Fendly, B., Kriegler, M. and Rosenberg, S.A. (1991). Murine tumor cells transduced with the gene for tumor necrosis factor-alpha. Evidence for paracrine immune effects of tumor necrosis factor against tumors. J. Immunol., 146: 3227-3234.
    • (1991) J. Immunol. , vol.146 , pp. 3227-3234
    • Asher, A.L.1    Mule, J.J.2    Kasid, A.3    Restifo, N.P.4    Salo, J.C.5    Reichert, C.M.6    Jaffe, G.7    Fendly, B.8    Kriegler, M.9    Rosenberg, S.A.10
  • 15
    • 0032546352 scopus 로고    scopus 로고
    • Dendritic cells and the control of immunity
    • Banchereau, J. and Steinman, R.M. (1998). Dendritic cells and the control of immunity. Nature, 19;392: 245-252.
    • (1998) Nature , vol.392 , Issue.6673 , pp. 245-252
    • Banchereau, J.1    Steinman, R.M.2
  • 16
    • 0036521570 scopus 로고    scopus 로고
    • Myeloprotection with drug-resistance genes
    • Banerjee, D. and Bertino, J.R. (2002). Myeloprotection with drug-resistance genes. Lancet Oncol., 3: 154-158.
    • (2002) Lancet Oncol. , vol.3 , pp. 154-158
    • Banerjee, D.1    Bertino, J.R.2
  • 19
    • 0027435064 scopus 로고
    • The potential of protein kinase C as a target for anticancer treatment
    • Basu, A. (1993). The potential of protein kinase C as a target for anticancer treatment. Pharmacol. Ther., 59: 257-280.
    • (1993) Pharmacol. Ther. , vol.59 , pp. 257-280
    • Basu, A.1
  • 21
    • 0001311122 scopus 로고    scopus 로고
    • Renal Tumors
    • P.C. Walsh, A.B. Retik, E.D. Vaughan and A.J. Wein (Eds.), W.B. Saunders, Philadelphia, PA
    • Belldegrun, A. and deKemion, J.B. (1998). Renal Tumors. In: Campell's Urology, P.C. Walsh, A.B. Retik, E.D. Vaughan and A.J. Wein (Eds.), W.B. Saunders, Philadelphia, PA, pp. 2292-2318.
    • (1998) Campell's Urology , pp. 2292-2318
    • Belldegrun, A.1    DeKemion, J.B.2
  • 25
    • 0033617532 scopus 로고    scopus 로고
    • Effects of angiogenesis inhibitors on multistage carcinogenesis in mice
    • Bergers, G., Javaherian, K., Lo, K.M., Folkman, J. and Hanahan, D. (1999). Effects of angiogenesis inhibitors on multistage carcinogenesis in mice. Science, 284: 808-812.
    • (1999) Science , vol.284 , pp. 808-812
    • Bergers, G.1    Javaherian, K.2    Lo, K.M.3    Folkman, J.4    Hanahan, D.5
  • 29
    • 0029397307 scopus 로고
    • The p53 gene and its role in human brain tumors
    • Bogler, O., Huang, H.J., Kleihues, P. and Cavenee, W.K. (1995). The p53 gene and its role in human brain tumors. Glia, 15: 308-327.
    • (1995) Glia , vol.15 , pp. 308-327
    • Bogler, O.1    Huang, H.J.2    Kleihues, P.3    Cavenee, W.K.4
  • 30
    • 0029924107 scopus 로고    scopus 로고
    • Human tumor antigens recognized by T lymphocytes
    • Boon, T. and van der Bruggen, P. (1996). Human tumor antigens recognized by T lymphocytes. J. Exp. Med., 183: 725-729.
    • (1996) J. Exp. Med. , vol.183 , pp. 725-729
    • Boon, T.1    Van Der Bruggen, P.2
  • 31
    • 0024376173 scopus 로고
    • Ras oncogenes in human cancer: A review
    • Bos, J.L. (1989). Ras oncogenes in human cancer: a review. Cancer Res., 49: 4682-4689.
    • (1989) Cancer Res. , vol.49 , pp. 4682-4689
    • Bos, J.L.1
  • 32
    • 0002263851 scopus 로고    scopus 로고
    • An overview on gene therapy
    • T. Boulikas (Ed.), Gene Therapy Press, Palo Alto, CA
    • Boulikas, T. (1998). An overview on gene therapy. In: Gene Therapy and Molecular Biology, T. Boulikas (Ed.), Gene Therapy Press, Palo Alto, CA, pp. 1-171.
    • (1998) Gene Therapy and Molecular Biology , pp. 1-171
    • Boulikas, T.1
  • 33
    • 0032101647 scopus 로고    scopus 로고
    • Adenovirus-mediated wild-type p53 gene transfer down-regulates vascular endothelial growth factor expression and inhibits angiogenesis in human colon cancer
    • Bouvet, M., Ellis, L.M., Nishizaki, M., Fujiwara, T., Liu, W., Bucana, C.D., Fang, B., Lee, J.J. and Roth, J.A. (1998). Adenovirus-mediated wild-type p53 gene transfer down-regulates vascular endothelial growth factor expression and inhibits angiogenesis in human colon cancer. Cancer Res., 58: 2288-2292.
    • (1998) Cancer Res. , vol.58 , pp. 2288-2292
    • Bouvet, M.1    Ellis, L.M.2    Nishizaki, M.3    Fujiwara, T.4    Liu, W.5    Bucana, C.D.6    Fang, B.7    Lee, J.J.8    Roth, J.A.9
  • 35
    • 0036560327 scopus 로고    scopus 로고
    • Cancer gene therapy with tissue inhibitors of metalloproteinases (TIMPs)
    • Brand, K. (2002). Cancer gene therapy with tissue inhibitors of metalloproteinases (TIMPs). Curr. Gene Ther., 2: 255-271.
    • (2002) Curr. Gene Ther. , vol.2 , pp. 255-271
    • Brand, K.1
  • 36
    • 0034667462 scopus 로고    scopus 로고
    • Treatment of colorectal liver metastases by adenoviral transfer of tissue inhibitor of metalloproteinases-2 into the liver tissue
    • Brand, K., Baker, A.H., Perez-Canto, A., Possling, A., Sacharjat, M., Geheeb, M. and Arnold, W. (2000). Treatment of colorectal liver metastases by adenoviral transfer of tissue inhibitor of metalloproteinases-2 into the liver tissue. Cancer Res., 60: 5723-5730.
    • (2000) Cancer Res. , vol.60 , pp. 5723-5730
    • Brand, K.1    Baker, A.H.2    Perez-Canto, A.3    Possling, A.4    Sacharjat, M.5    Geheeb, M.6    Arnold, W.7
  • 37
    • 0035120593 scopus 로고    scopus 로고
    • Replicating adenoviruses that target tumors with constitutive activation of the wnt signaling pathway
    • Brunori, M., Malerba, M., Kashiwazaki, H. and Iggo, R. (2001). Replicating adenoviruses that target tumors with constitutive activation of the wnt signaling pathway. J. Virol., 75: 2857-2865.
    • (2001) J. Virol. , vol.75 , pp. 2857-2865
    • Brunori, M.1    Malerba, M.2    Kashiwazaki, H.3    Iggo, R.4
  • 39
    • 0027228422 scopus 로고
    • Vesicular stomatitis virus G glycoprotein pseudotyped retroviral vectors: Concentration to very high titer and efficient gene transfer into mammalian and nonmammalian cells
    • Burns, J.C., Friedmann, T., Driever, W., Burrascano, M. and Yee, J.K. (1993). Vesicular stomatitis virus G glycoprotein pseudotyped retroviral vectors: concentration to very high titer and efficient gene transfer into mammalian and nonmammalian cells. Proc. Natl. Acad. Sci. USA, 90: 8033-8037.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 8033-8037
    • Burns, J.C.1    Friedmann, T.2    Driever, W.3    Burrascano, M.4    Yee, J.K.5
  • 40
    • 0032031748 scopus 로고    scopus 로고
    • Expression of angiostatin cDNA in a murine fibrosarcoma suppresses primary tumor growth and produces long-term dormancy of metastases
    • Cao, Y., O'Reilly, M.S., Marshall, B., Flynn, E., Ji, R.W. and Folkman, J. (1998). Expression of angiostatin cDNA in a murine fibrosarcoma suppresses primary tumor growth and produces long-term dormancy of metastases. J. Clin. Invest., 101: 1055-1063.
    • (1998) J. Clin. Invest. , vol.101 , pp. 1055-1063
    • Cao, Y.1    O'Reilly, M.S.2    Marshall, B.3    Flynn, E.4    Ji, R.W.5    Folkman, J.6
  • 41
    • 0034648765 scopus 로고    scopus 로고
    • Angiogenesis in cancer and other diseases
    • Carmeliet, P. and Jain, R.K. (2000). Angiogenesis in cancer and other diseases. Nature, 407: 249-257.
    • (2000) Nature , vol.407 , pp. 249-257
    • Carmeliet, P.1    Jain, R.K.2
  • 42
    • 0033556011 scopus 로고    scopus 로고
    • Immune events associated with the cure of established tumors and spontaneous metastases by local and systemic interleukin 12
    • Cavallo, F., Di Carlo, E., Butera, M., Verrua, R., Colombo, M.P., Musiani, P. and Forni, G. (1999). Immune events associated with the cure of established tumors and spontaneous metastases by local and systemic interleukin 12. Cancer Res., 59: 414-421.
    • (1999) Cancer Res. , vol.59 , pp. 414-421
    • Cavallo, F.1    Di Carlo, E.2    Butera, M.3    Verrua, R.4    Colombo, M.P.5    Musiani, P.6    Forni, G.7
  • 44
    • 0031027417 scopus 로고    scopus 로고
    • Adoptive immunotherapy with vaccine-primed lymph node cells secondarily activated with anti-CD3 and interleukin-2
    • Chang, A.E., Aruga, A., Cameron, M.J., Sondak, V.K., Normolle, D.P., Fox, B.A. and Shu, S. (1997). Adoptive immunotherapy with vaccine-primed lymph node cells secondarily activated with anti-CD3 and interleukin-2. J. Clin. Oncol., 15: 796-807.
    • (1997) J. Clin. Oncol. , vol.15 , pp. 796-807
    • Chang, A.E.1    Aruga, A.2    Cameron, M.J.3    Sondak, V.K.4    Normolle, D.P.5    Fox, B.A.6    Shu, S.7
  • 45
    • 0034630307 scopus 로고    scopus 로고
    • Immunogenetic therapy of human melanoma utilizing autologous tumor cells transduced to secrete granulocyte-macrophage colony-stimulating factor
    • Chang, A.E., Li, Q., Bishop, D.K., Normolle, D.P., Redman, B.D. and Nickoloff, B.J. (2000). Immunogenetic therapy of human melanoma utilizing autologous tumor cells transduced to secrete granulocyte-macrophage colony-stimulating factor. Hum. Gene Ther., 11: 839-850.
    • (2000) Hum. Gene Ther. , vol.11 , pp. 839-850
    • Chang, A.E.1    Li, Q.2    Bishop, D.K.3    Normolle, D.P.4    Redman, B.D.5    Nickoloff, B.J.6
  • 46
    • 0028202066 scopus 로고
    • Gene therapy for brain tumors: Regression of experimental gliomas by adenovirus-mediated gene transfer in vivo
    • Chen, S.H., Shine, H.D., Goodman, J.C., Grossman, R.G. and Woo, S.L. (1994). Gene therapy for brain tumors: regression of experimental gliomas by adenovirus-mediated gene transfer in vivo. Proc. Natl. Acad. Sci. USA, 91: 3054-3057.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 3054-3057
    • Chen, S.H.1    Shine, H.D.2    Goodman, J.C.3    Grossman, R.G.4    Woo, S.L.5
  • 48
    • 0033902946 scopus 로고    scopus 로고
    • Structure and function of lipid-DNA complexes for gene delivery
    • Chesnoy, S. and Huang, L. (2000). Structure and function of lipid-DNA complexes for gene delivery. Annu. Rev. Biophys. Biomol. Struct., 29: 27-47.
    • (2000) Annu. Rev. Biophys. Biomol. Struct. , vol.29 , pp. 27-47
    • Chesnoy, S.1    Huang, L.2
  • 52
    • 0032809839 scopus 로고    scopus 로고
    • Adenovirus-mediated wild-type p53 gene transfer as a surgical adjuvant in advanced head and neck cancers
    • Clayman, G.L., Frank, D.K., Bruso, P.A. and Goepfert, H. (1999). Adenovirus-mediated wild-type p53 gene transfer as a surgical adjuvant in advanced head and neck cancers. Clin. Cancer Res., 5: 1715-1722.
    • (1999) Clin. Cancer Res. , vol.5 , pp. 1715-1722
    • Clayman, G.L.1    Frank, D.K.2    Bruso, P.A.3    Goepfert, H.4
  • 53
    • 0023889371 scopus 로고
    • An evaluation of the palliative role of radiotherapy in inoperable carcinoma of the bronchus
    • Collins, T.M., Ash, D.V., Close, H.J. and Thorogood, J. (1988). An evaluation of the palliative role of radiotherapy in inoperable carcinoma of the bronchus. Clin. Radiol., 39: 284-286.
    • (1988) Clin. Radiol. , vol.39 , pp. 284-286
    • Collins, T.M.1    Ash, D.V.2    Close, H.J.3    Thorogood, J.4
  • 54
    • 0025852249 scopus 로고
    • Granulocyte colony-stimulating factor gene transfer suppresses tumorigenicity of a murine adenocarcinoma in vivo
    • Colombo, M.P., Ferrari, G., Stoppacciaro, A., Parenza, M., Rodolfo, M., Mavilio, F. and Parmiani, G. (1991). Granulocyte colony-stimulating factor gene transfer suppresses tumorigenicity of a murine adenocarcinoma in vivo. J. Exp. Med., 173: 889-897.
    • (1991) J. Exp. Med. , vol.173 , pp. 889-897
    • Colombo, M.P.1    Ferrari, G.2    Stoppacciaro, A.3    Parenza, M.4    Rodolfo, M.5    Mavilio, F.6    Parmiani, G.7
  • 55
    • 14444284332 scopus 로고    scopus 로고
    • Effects of adenovirus-mediated p16INK4A expression on cell cycle arrest are determined by endogenous p16 and Rb status in human cancer cells
    • Craig, C., Kim, M., Ohri, E., Wersto, R., Katayose, D., Li, Z., Choi, Y.H., Mudahar, B., Srivastava, S., Seth, P. and Cowan, K. (1998). Effects of adenovirus-mediated p16INK4A expression on cell cycle arrest are determined by endogenous p16 and Rb status in human cancer cells. Oncogene, 16: 265-272.
    • (1998) Oncogene , vol.16 , pp. 265-272
    • Craig, C.1    Kim, M.2    Ohri, E.3    Wersto, R.4    Katayose, D.5    Li, Z.6    Choi, Y.H.7    Mudahar, B.8    Srivastava, S.9    Seth, P.10    Cowan, K.11
  • 56
    • 0026772206 scopus 로고
    • In vivo gene transfer with retroviral vector-producer cells for treatment of experimental brain tumors
    • Culver, K.W., Ram, Z., Wallbridge, S., Ishii, H., Oldfield, E.H. and Blaese, R.M. (1992). In vivo gene transfer with retroviral vector-producer cells for treatment of experimental brain tumors. Science, 256: 1550-1552.
    • (1992) Science , vol.256 , pp. 1550-1552
    • Culver, K.W.1    Ram, Z.2    Wallbridge, S.3    Ishii, H.4    Oldfield, E.H.5    Blaese, R.M.6
  • 57
    • 0034026007 scopus 로고    scopus 로고
    • A phase I trial of c-Raf kinase antisense oligonucleotide ISIS 5132 administered as a continuous intravenous infusion in patients with advanced cancer
    • Cunningham, C.C., Holmlund, J.T., Schiller, J.H., Geary, R.S., Kwoh, T.J., Dorr, A. and Nemunaitis, J. (2000). A phase I trial of c-Raf kinase antisense oligonucleotide ISIS 5132 administered as a continuous intravenous infusion in patients with advanced cancer. Clin. Cancer Res., 6: 1626-1631.
    • (2000) Clin. Cancer Res. , vol.6 , pp. 1626-1631
    • Cunningham, C.C.1    Holmlund, J.T.2    Schiller, J.H.3    Geary, R.S.4    Kwoh, T.J.5    Dorr, A.6    Nemunaitis, J.7
  • 58
    • 0028062847 scopus 로고
    • Inhibition of protein kinase C-alpha expression in mice after systemic administration of phosphorothioate antisense oligodeoxynucleotides
    • Dean, N.M. and McKay, R. (1994). Inhibition of protein kinase C-alpha expression in mice after systemic administration of phosphorothioate antisense oligodeoxynucleotides. Proc. Natl. Acad. Sci. USA, 91: 11762-11766.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 11762-11766
    • Dean, N.M.1    McKay, R.2
  • 60
    • 0035015925 scopus 로고    scopus 로고
    • Does the antitumor adenovirus ONYX-015/d11520 selectively target cells defective in the p53 pathway?
    • Dix, B.R., Edwards, S.J. and Braithwaite, A.W. (2001). Does the antitumor adenovirus ONYX-015/d11520 selectively target cells defective in the p53 pathway? J. Virol., 75: 5443-5447.
    • (2001) J. Virol. , vol.75 , pp. 5443-5447
    • Dix, B.R.1    Edwards, S.J.2    Braithwaite, A.W.3
  • 61
    • 0035100867 scopus 로고    scopus 로고
    • Tissue-specific, tumor-selective, replication-competent adenovirus vector for cancer gene therapy
    • Doronin, K., Kuppuswamy, M., Toth, K., Tollefson, A.E., Krajcsi, P., Krougliak, V. and Wold, W.S. (2001). Tissue-specific, tumor-selective, replication-competent adenovirus vector for cancer gene therapy. J. Virol., 75: 3314-3324.
    • (2001) J. Virol. , vol.75 , pp. 3314-3324
    • Doronin, K.1    Kuppuswamy, M.2    Toth, K.3    Tollefson, A.E.4    Krajcsi, P.5    Krougliak, V.6    Wold, W.S.7
  • 62
    • 0027538181 scopus 로고
    • Vaccination with irradiated tumor cells engineered to secrete murine granulocyte-macrophage colony-stimulating factor stimulates potent, specific, and long-lasting anti-tumor immunity
    • Dranoff, G., Jaffee, E., Lazenby, A., Golumbek, P., Levitsky, H., Brose, K., Jackson, V., Hamada, H., Pardoll, D. and Mulligan, R.C. (1993). Vaccination with irradiated tumor cells engineered to secrete murine granulocyte-macrophage colony-stimulating factor stimulates potent, specific, and long-lasting anti-tumor immunity. Proc. Natl. Acad. Sci. USA, 90: 3539-3543.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 3539-3543
    • Dranoff, G.1    Jaffee, E.2    Lazenby, A.3    Golumbek, P.4    Levitsky, H.5    Brose, K.6    Jackson, V.7    Hamada, H.8    Pardoll, D.9    Mulligan, R.C.10
  • 63
    • 0033914837 scopus 로고    scopus 로고
    • Biological activity and safety of adenoviral vector-expressed wild-type p53 after intratumoral injection in melanoma and breast cancer patients with p53-overexpressing tumors
    • Dummer, R., Bergh, J., Karlsson, Y., Horowitz, J.A., Mulder, N.H., Huinink, D.T., Burg, G., Hofbauer, G. and Osanto, S. (2000). Biological activity and safety of adenoviral vector-expressed wild-type p53 after intratumoral injection in melanoma and breast cancer patients with p53-overexpressing tumors. Cancer Gene Ther., 7: 1069-1076.
    • (2000) Cancer Gene Ther. , vol.7 , pp. 1069-1076
    • Dummer, R.1    Bergh, J.2    Karlsson, Y.3    Horowitz, J.A.4    Mulder, N.H.5    Huinink, D.T.6    Burg, G.7    Hofbauer, G.8    Osanto, S.9
  • 64
    • 0029924404 scopus 로고    scopus 로고
    • Prostate cancer gene therapy: Herpes simplex virus thymidine kinase gene transduction followed by ganciclovir in mouse and human prostate cancer models
    • Eastham, J.A., Chen, S.H., Sehgal, I., Yang, G., Timme, T.L., Hall, S.J., Woo, S.L. and Thompson, T.C. (1996). Prostate cancer gene therapy: herpes simplex virus thymidine kinase gene transduction followed by ganciclovir in mouse and human prostate cancer models. Hum. Gene Ther., 7: 515-523.
    • (1996) Hum. Gene Ther. , vol.7 , pp. 515-523
    • Eastham, J.A.1    Chen, S.H.2    Sehgal, I.3    Yang, G.4    Timme, T.L.5    Hall, S.J.6    Woo, S.L.7    Thompson, T.C.8
  • 66
    • 0036222328 scopus 로고    scopus 로고
    • Unfulfilled promise of endostatin in a gene therapy-xenotransplant model of human acute lymphocytic leukemia
    • Eisterer, W., Jiang, X., Bachelot, T., Pawliuk, R., Abramovich, C., Leboulch, P., Hogge, D. and Eaves, C. (2002). Unfulfilled promise of endostatin in a gene therapy-xenotransplant model of human acute lymphocytic leukemia. Mol. Ther., 5: 352-359.
    • (2002) Mol. Ther. , vol.5 , pp. 352-359
    • Eisterer, W.1    Jiang, X.2    Bachelot, T.3    Pawliuk, R.4    Abramovich, C.5    Leboulch, P.6    Hogge, D.7    Eaves, C.8
  • 67
    • 0028978033 scopus 로고
    • Cytokine gene therapy with interleukin-2-transduced fibroblasts: Effects of IL-2 dose on anti-tumor immunity
    • Fakhrai, H., Shawler, D.L., Gjerset, R., Naviaux, R.K., Koziol, J., Royston, I. and Sobol, R.E. (1995). Cytokine gene therapy with interleukin-2-transduced fibroblasts: effects of IL-2 dose on anti-tumor immunity. Hum. Gene Ther., 6: 591-601.
    • (1995) Hum. Gene Ther. , vol.6 , pp. 591-601
    • Fakhrai, H.1    Shawler, D.L.2    Gjerset, R.3    Naviaux, R.K.4    Koziol, J.5    Royston, I.6    Sobol, R.E.7
  • 70
    • 0032859385 scopus 로고    scopus 로고
    • Lentiviruses as gene delivery vectors
    • Federico, M. (1999). Lentiviruses as gene delivery vectors. Curr. Opin. Biotechnol., 10: 448-453.
    • (1999) Curr. Opin. Biotechnol. , vol.10 , pp. 448-453
    • Federico, M.1
  • 71
    • 0031178573 scopus 로고    scopus 로고
    • Increase of cytotoxic sensitivity of primary human melanoma cells transfected with the interleukin-7 gene to autologous and allogeneic immunologic effector cells
    • Finke, S., Trojaneck, B., Moller, P., Schadendorf, D., Neubauer, A., Huhn, D. and Schmidt-Wolf, I.G. (1997). Increase of cytotoxic sensitivity of primary human melanoma cells transfected with the interleukin-7 gene to autologous and allogeneic immunologic effector cells. Cancer Gene Ther., 4: 260-268.
    • (1997) Cancer Gene Ther. , vol.4 , pp. 260-268
    • Finke, S.1    Trojaneck, B.2    Moller, P.3    Schadendorf, D.4    Neubauer, A.5    Huhn, D.6    Schmidt-Wolf, I.G.7
  • 72
    • 0030242225 scopus 로고    scopus 로고
    • Fighting cancer by attacking its blood supply
    • Folkman, J. (1996). Fighting cancer by attacking its blood supply. Sci. Am., 275: 150-154.
    • (1996) Sci. Am. , vol.275 , pp. 150-154
    • Folkman, J.1
  • 74
    • 0031755588 scopus 로고    scopus 로고
    • Bystander effect in the adenovirus-mediated wild-type p53 gene therapy model of human squamous cell carcinoma of the head and neck
    • Frank, D.K., Frederick, M.J., Liu, T.J. and Clayman, G.L. (1998). Bystander effect in the adenovirus-mediated wild-type p53 gene therapy model of human squamous cell carcinoma of the head and neck. Clin. Cancer Res., 4: 2521-2528.
    • (1998) Clin. Cancer Res. , vol.4 , pp. 2521-2528
    • Frank, D.K.1    Frederick, M.J.2    Liu, T.J.3    Clayman, G.L.4
  • 75
    • 0032503659 scopus 로고    scopus 로고
    • A novel three-pronged approach to kill cancer cells selectively: Concomitant viral, double suicide gene, and radiotherapy
    • Freytag, S.O., Rogulski, K.R., Paielli, D.L., Gilbert, J.D. and Kim, J.H. (1998). A novel three-pronged approach to kill cancer cells selectively: concomitant viral, double suicide gene, and radiotherapy. Hum. Gene Ther., 9: 1323-1333.
    • (1998) Hum. Gene Ther. , vol.9 , pp. 1323-1333
    • Freytag, S.O.1    Rogulski, K.R.2    Paielli, D.L.3    Gilbert, J.D.4    Kim, J.H.5
  • 77
    • 0028865226 scopus 로고
    • Adenovirus E1a-mediated tumor suppression by a c-erbB-2/neu-independent mechanism
    • Frisch, S.M. and Dolter, K.E. (1995). Adenovirus E1a-mediated tumor suppression by a c-erbB-2/neu-independent mechanism. Cancer Res., 55: 5551-5555.
    • (1995) Cancer Res. , vol.55 , pp. 5551-5555
    • Frisch, S.M.1    Dolter, K.E.2
  • 79
    • 0033778639 scopus 로고    scopus 로고
    • Induction of melanoma-associated antigen systemic immunity upon intratumoral delivery of interferon-gamma retroviral vector in melanoma patients
    • Fujii, S., Huang, S., Fong, T.C., Ando, D., Burrows, F., Jolly, D.J., Nemunaitis, J. and Hoon, D.S. (2000). Induction of melanoma-associated antigen systemic immunity upon intratumoral delivery of interferon-gamma retroviral vector in melanoma patients. Cancer Gene Ther., 7: 1220-1230.
    • (2000) Cancer Gene Ther. , vol.7 , pp. 1220-1230
    • Fujii, S.1    Huang, S.2    Fong, T.C.3    Ando, D.4    Burrows, F.5    Jolly, D.J.6    Nemunaitis, J.7    Hoon, D.S.8
  • 80
    • 0028929682 scopus 로고
    • Results of treatment of 255 patients with metastatic renal cell carcinoma who received high-dose recombinant interleukin-2 therapy
    • Fyfe, G., Fisher, R.I., Rosenberg, S.A., Sznol, M., Parkinson, D.R. and Louie, A.C. (1995). Results of treatment of 255 patients with metastatic renal cell carcinoma who received high-dose recombinant interleukin-2 therapy. J. Clin. Oncol., 13: 688-696.
    • (1995) J. Clin. Oncol. , vol.13 , pp. 688-696
    • Fyfe, G.1    Fisher, R.I.2    Rosenberg, S.A.3    Sznol, M.4    Parkinson, D.R.5    Louie, A.C.6
  • 83
    • 0032853334 scopus 로고    scopus 로고
    • Antisense oligonucleotides as therapeutic agents
    • Galderisi, U., Cascino, A. and Giordano, A. (1999). Antisense oligonucleotides as therapeutic agents. J. Cell Physiol., 181: 251-257.
    • (1999) J. Cell Physiol. , vol.181 , pp. 251-257
    • Galderisi, U.1    Cascino, A.2    Giordano, A.3
  • 85
    • 0025000864 scopus 로고
    • Interleukin 2 gene transfer into tumor cells abrogates tumorigenicity and induces protective immunity
    • Gansbacher, B., Zier, K., Daniels, B., Cronin, K., Bannerji, R. and Gilboa, E. (1990). Interleukin 2 gene transfer into tumor cells abrogates tumorigenicity and induces protective immunity. J. Exp. Med., 172: 1217-1224.
    • (1990) J. Exp. Med. , vol.172 , pp. 1217-1224
    • Gansbacher, B.1    Zier, K.2    Daniels, B.3    Cronin, K.4    Bannerji, R.5    Gilboa, E.6
  • 88
    • 0034820992 scopus 로고    scopus 로고
    • Phase i study of intravesical vaccinia virus as a vector for gene therapy of bladder cancer
    • Gomella, L.G., Mastrangelo, M.J., McCue, P.A., Maguire, H.C., Mulholland, S.G. and Lattime, E.C. (2001). Phase i study of intravesical vaccinia virus as a vector for gene therapy of bladder cancer. J. Urol., 166: 1291-1295.
    • (2001) J. Urol. , vol.166 , pp. 1291-1295
    • Gomella, L.G.1    Mastrangelo, M.J.2    McCue, P.A.3    Maguire, H.C.4    Mulholland, S.G.5    Lattime, E.C.6
  • 93
    • 0032990031 scopus 로고    scopus 로고
    • Adenovirus-mediated p53 gene therapy has greater efficacy when combined with chemotherapy against human head and neck, ovarian, prostate, and breast cancer
    • Gurnani, M., Lipari, P., Dell, J., Shi, B. and Nielsen, L.L. (1999). Adenovirus-mediated p53 gene therapy has greater efficacy when combined with chemotherapy against human head and neck, ovarian, prostate, and breast cancer. Cancer Chemother. Pharmacol., 44: 143-151.
    • (1999) Cancer Chemother. Pharmacol. , vol.44 , pp. 143-151
    • Gurnani, M.1    Lipari, P.2    Dell, J.3    Shi, B.4    Nielsen, L.L.5
  • 94
    • 0025190829 scopus 로고
    • Tumor-infiltrating lymphocytes from nonrenal urological malignancies
    • Haas, G.P., Solomon, D. and Rosenberg, S.A. (1990). Tumor-infiltrating lymphocytes from nonrenal urological malignancies. Cancer Immunol. Immunother., 30: 342-350.
    • (1990) Cancer Immunol. Immunother. , vol.30 , pp. 342-350
    • Haas, G.P.1    Solomon, D.2    Rosenberg, S.A.3
  • 96
    • 0027787055 scopus 로고
    • Adenoviral interleukin-2 gene transfer into P815 tumor cells abrogates tumorigenicity and induces antitumoral immunity in mice
    • Haddada, H., Ragot, T., Cordier, L., Duffour, M.T. and Perricaudet, M. (1993). Adenoviral interleukin-2 gene transfer into P815 tumor cells abrogates tumorigenicity and induces antitumoral immunity in mice. Hum. Gene Ther., 4: 703-711.
    • (1993) Hum. Gene Ther. , vol.4 , pp. 703-711
    • Haddada, H.1    Ragot, T.2    Cordier, L.3    Duffour, M.T.4    Perricaudet, M.5
  • 99
    • 0031027728 scopus 로고    scopus 로고
    • Adenovirus-mediated herpes simplex virus thymidine kinase gene and ganciclovir therapy leads to systemic activity against spontaneous and induced metastasis in an orthotopic mouse model of prostate cancer
    • Hall, S.J., Mutchnik, S.E., Chen, S.H., Woo, S.L. and Thompson, T.C. (1997). Adenovirus-mediated herpes simplex virus thymidine kinase gene and ganciclovir therapy leads to systemic activity against spontaneous and induced metastasis in an orthotopic mouse model of prostate cancer. Int. J. Cancer, 70: 183-187.
    • (1997) Int. J. Cancer , vol.70 , pp. 183-187
    • Hall, S.J.1    Mutchnik, S.E.2    Chen, S.H.3    Woo, S.L.4    Thompson, T.C.5
  • 100
    • 0033166096 scopus 로고    scopus 로고
    • A novel tumor-specific replication-restricted adenoviral vector for gene therapy of hepatocellular carcinoma
    • Hallenbeck, P.L., Chang, Y.N., Hay, C., Golightly, D., Stewart, D., Lin, J., Phipps, S. and Chiang, Y.L. (1999). A novel tumor-specific replication-restricted adenoviral vector for gene therapy of hepatocellular carcinoma. Hum. Gene Ther., 10: 1721-1733.
    • (1999) Hum. Gene Ther. , vol.10 , pp. 1721-1733
    • Hallenbeck, P.L.1    Chang, Y.N.2    Hay, C.3    Golightly, D.4    Stewart, D.5    Lin, J.6    Phipps, S.7    Chiang, Y.L.8
  • 104
    • 0030021996 scopus 로고    scopus 로고
    • Inactivation of p53 enhances sensitivity to multiple chemotherapeutic agents
    • Hawkins, D.S., Demers, G.W. and Galloway, D.A. (1996). Inactivation of p53 enhances sensitivity to multiple chemotherapeutic agents. Cancer Res., 56: 892-898.
    • (1996) Cancer Res. , vol.56 , pp. 892-898
    • Hawkins, D.S.1    Demers, G.W.2    Galloway, D.A.3
  • 105
    • 0037314610 scopus 로고    scopus 로고
    • A phase I/II trial of intratumoral endoscopic ultrasound injection of ONYX-015 with intravenous gemcitabine in unresectable pancreatic carcinoma
    • Hecht, J.R., Bedford, R., Abbruzzese, J.L., Lahoti, S., Reid, T.R., Soetikno, R.M., Kirn, D.H. and Freeman, S.M. (2003). A phase I/II trial of intratumoral endoscopic ultrasound injection of ONYX-015 with intravenous gemcitabine in unresectable pancreatic carcinoma. Clin. Cancer Res., 9: 555-561.
    • (2003) Clin. Cancer Res. , vol.9 , pp. 555-561
    • Hecht, J.R.1    Bedford, R.2    Abbruzzese, J.L.3    Lahoti, S.4    Reid, T.R.5    Soetikno, R.M.6    Kirn, D.H.7    Freeman, S.M.8
  • 107
    • 0032100841 scopus 로고    scopus 로고
    • The role of chemotherapy and radiation in the management of biliary cancer: A review of the literature
    • Hejna, M., Pruckmayer, M. and Raderer, M. (1998). The role of chemotherapy and radiation in the management of biliary cancer: a review of the literature. Eur. J. Cancer, 34: 977-986.
    • (1998) Eur. J. Cancer , vol.34 , pp. 977-986
    • Hejna, M.1    Pruckmayer, M.2    Raderer, M.3
  • 108
    • 0000326946 scopus 로고    scopus 로고
    • Sequence-specific control of gene expression by antigene and clamp oligonucleotides
    • T. Boulikas (Ed.), Gene Therapy Press, Palo Alto, CA
    • Helene, C., Garestier, T., Giovannageli, C. and Sun, J. (1998). Sequence-specific control of gene expression by antigene and clamp oligonucleotides. In: Gene therapy and molecular biology, T. Boulikas (Ed.), Gene Therapy Press, Palo Alto, CA, pp. 467-474.
    • (1998) Gene Therapy and Molecular Biology , pp. 467-474
    • Helene, C.1    Garestier, T.2    Giovannageli, C.3    Sun, J.4
  • 109
    • 0036162121 scopus 로고    scopus 로고
    • From molecular changes to customised therapy
    • Hemminki, A. (2002). From molecular changes to customised therapy. Eur. J. Cancer, 38: 333-338.
    • (2002) Eur. J. Cancer , vol.38 , pp. 333-338
    • Hemminki, A.1
  • 111
    • 0037296417 scopus 로고    scopus 로고
    • Dose-comparative monotherapy trials of ZD 1839 in previously treated non-small cell lung cancer patients
    • Herbst, R.S. (2003). Dose-comparative monotherapy trials of ZD 1839 in previously treated non-small cell lung cancer patients. Semin. Oncol., 30: 30-38.
    • (2003) Semin. Oncol. , vol.30 , pp. 30-38
    • Herbst, R.S.1
  • 113
    • 0027394642 scopus 로고
    • Vaccinations with tumor cells genetically engineered to produce different cytokines: Effectivity not superior to a classical adjuvant
    • Hock, H., Dorsch, M., Kunzendorf, U., Uberla, K., Qin, Z., Diamantstein, T. and Blankenstein, T. (1993). Vaccinations with tumor cells genetically engineered to produce different cytokines: effectivity not superior to a classical adjuvant. Cancer Res., 53: 714-716.
    • (1993) Cancer Res. , vol.53 , pp. 714-716
    • Hock, H.1    Dorsch, M.2    Kunzendorf, U.3    Uberla, K.4    Qin, Z.5    Diamantstein, T.6    Blankenstein, T.7
  • 117
    • 0027512782 scopus 로고
    • Adjuvant active specific immunotherapy for human colorectal cancer: 6.5-Year median follow-up of a phase III prospectively randomized trial
    • Hoover, H.C., Brandhorst, J. S., Peters, L.C., Surdyke, M.G., Takeshita, Y., Madariaga, J., Muenz, L.R. and Hanna, M.G. (1993). Adjuvant active specific immunotherapy for human colorectal cancer: 6.5-year median follow-up of a phase III prospectively randomized trial. J. Clin. Oncol., 11: 390-399.
    • (1993) J. Clin. Oncol. , vol.11 , pp. 390-399
    • Hoover, H.C.1    Brandhorst, J.S.2    Peters, L.C.3    Surdyke, M.G.4    Takeshita, Y.5    Madariaga, J.6    Muenz, L.R.7    Hanna, M.G.8
  • 118
    • 0032189117 scopus 로고    scopus 로고
    • Treatment of breast cancer
    • Hortobagyi, G.N. (1998). Treatment of breast cancer. N. Engl. J. Med., 339: 974-984.
    • (1998) N. Engl. J. Med. , vol.339 , pp. 974-984
    • Hortobagyi, G.N.1
  • 119
    • 0034659774 scopus 로고    scopus 로고
    • Developments in chemotherapy of breast cancer
    • Hortobagyi, G.N. (2000). Developments in chemotherapy of breast cancer. Cancer, 88: 3073-3079.
    • (2000) Cancer , vol.88 , pp. 3073-3079
    • Hortobagyi, G.N.1
  • 121
    • 0036316020 scopus 로고    scopus 로고
    • Gene therapy for pancreatic cancer using an adenovirus vector encoding soluble flt-1 vascular endothelial growth factor receptor
    • Hoshida, T., Sunamura, M., Duda, D.G., Egawa, S., Miyazaki, S., Shineha, R., Hamada, H., Ohtani, H., Satomi, S. and Matsuno, S. (2002). Gene therapy for pancreatic cancer using an adenovirus vector encoding soluble flt-1 vascular endothelial growth factor receptor. Pancreas, 25: 111-121.
    • (2002) Pancreas , vol.25 , pp. 111-121
    • Hoshida, T.1    Sunamura, M.2    Duda, D.G.3    Egawa, S.4    Miyazaki, S.5    Shineha, R.6    Hamada, H.7    Ohtani, H.8    Satomi, S.9    Matsuno, S.10
  • 122
    • 0028179056 scopus 로고
    • Role of bone marrow-derived cells in presenting MHC class I-restricted tumor antigens
    • Huang, A.Y., Golumbek, P., Ahmadzadeh, M., Jaffee, E., Pardoll, D. and Levitsky, H. (1994). Role of bone marrow-derived cells in presenting MHC class I-restricted tumor antigens. Science, 264: 961-965.
    • (1994) Science , vol.264 , pp. 961-965
    • Huang, A.Y.1    Golumbek, P.2    Ahmadzadeh, M.3    Jaffee, E.4    Pardoll, D.5    Levitsky, H.6
  • 123
    • 0030845845 scopus 로고    scopus 로고
    • Phase I study of immunotherapy of cutaneous metastases of human carcinoma using allogeneic and xenogeneic MHC DNA-liposome complexes
    • Hui, K.M., Ang, P.T., Huang, L. and Tay, S.K. (1997). Phase I study of immunotherapy of cutaneous metastases of human carcinoma using allogeneic and xenogeneic MHC DNA-liposome complexes. Gene Therapy, 4: 783-790.
    • (1997) Gene Therapy , vol.4 , pp. 783-790
    • Hui, K.M.1    Ang, P.T.2    Huang, L.3    Tay, S.K.4
  • 125
    • 0034185044 scopus 로고    scopus 로고
    • Anticorresponding mutations of the KRAS and PTEN genes in human endometrial cancer
    • Ikeda, T., Yoshinaga, K., Suzuki, A., Sakurada, A., Ohmori, H. and Horii, A. (2000). Anticorresponding mutations of the KRAS and PTEN genes in human endometrial cancer. Oncol. Rep., 7: 567-570.
    • (2000) Oncol. Rep. , vol.7 , pp. 567-570
    • Ikeda, T.1    Yoshinaga, K.2    Suzuki, A.3    Sakurada, A.4    Ohmori, H.5    Horii, A.6
  • 130
    • 0031052827 scopus 로고    scopus 로고
    • Optimized conditions for the production of recombinant amphotropic retroviral vector preparations
    • Kaptein, L.C., Greijer, A.E., Valerio, D. and van Beusechem, V.W. (1997). Optimized conditions for the production of recombinant amphotropic retroviral vector preparations. Gene Therapy, 4: 172-176.
    • (1997) Gene Therapy , vol.4 , pp. 172-176
    • Kaptein, L.C.1    Greijer, A.E.2    Valerio, D.3    Van Beusechem, V.W.4
  • 131
    • 0033910714 scopus 로고    scopus 로고
    • Comparative studies of the effects of recombinant GM-CSF and GM-CSF administered via a poxvirus to enhance the concentration of antigen-presenting cells in regional lymph nodes
    • Kass, E., Parker, J., Schlom, J. and Greiner, J.W. (2000). Comparative studies of the effects of recombinant GM-CSF and GM-CSF administered via a poxvirus to enhance the concentration of antigen-presenting cells in regional lymph nodes. Cytokine, 12: 960-971.
    • (2000) Cytokine , vol.12 , pp. 960-971
    • Kass, E.1    Parker, J.2    Schlom, J.3    Greiner, J.W.4
  • 133
    • 0032601767 scopus 로고    scopus 로고
    • Arterial, portal, or systemic chemotherapy for patients with hepatic metastasis of colorectal carcinoma
    • Kemeny, N. and Fata, F. (1999). Arterial, portal, or systemic chemotherapy for patients with hepatic metastasis of colorectal carcinoma. J. Hepatobiliary. Pancreat. Surg., 6: 39-49.
    • (1999) J. Hepatobiliary. Pancreat. Surg. , vol.6 , pp. 39-49
    • Kemeny, N.1    Fata, F.2
  • 134
    • 0141885308 scopus 로고    scopus 로고
    • The evolving role of docetaxel in the management of androgen independent prostate cancer
    • Khan, M.A., Carducci, M.A. and Partin, A.W. (2003). The evolving role of docetaxel in the management of androgen independent prostate cancer. J. Urol., 170: 1709-1716.
    • (2003) J. Urol. , vol.170 , pp. 1709-1716
    • Khan, M.A.1    Carducci, M.A.2    Partin, A.W.3
  • 137
    • 0141501192 scopus 로고    scopus 로고
    • Targeted therapies for the treatment of cancer
    • Kim, J.A. (2003). Targeted therapies for the treatment of cancer. Am. J. Surg., 186: 264-268.
    • (2003) Am. J. Surg. , vol.186 , pp. 264-268
    • Kim, J.A.1
  • 138
    • 0034927057 scopus 로고    scopus 로고
    • Replication-selective virotherapy for cancer: Biological principles, risk management and future directions
    • Kim, D., Martuza, R.L. and Zwiebel, J. (2001). Replication-selective virotherapy for cancer: Biological principles, risk management and future directions. Nat. Med., 7: 781-787.
    • (2001) Nat. Med. , vol.7 , pp. 781-787
    • Kim, D.1    Martuza, R.L.2    Zwiebel, J.3
  • 139
    • 0031717905 scopus 로고    scopus 로고
    • Tumor-suppressor p53: Implications for tumor development and prognosis
    • Kirsch, D.G. and Kastan, M.B. (1998). Tumor-suppressor p53: implications for tumor development and prognosis. J. Clin. Oncol., 16: 3158-3168.
    • (1998) J. Clin. Oncol. , vol.16 , pp. 3158-3168
    • Kirsch, D.G.1    Kastan, M.B.2
  • 140
    • 2442721450 scopus 로고    scopus 로고
    • A phase I/II dose-escalation study of herpes simplex virus type 1 thymidine kinase "suicide" gene therapy for metastatic melanoma
    • Study Group on Gene Therapy of Metastatic Melanoma
    • Klatzmann, D., Cherin, P., Bensimon, G., Boyer, O., Coutellier, A., Charlotte, F., Boccaccio, C., Salzmann, J.L. and Herson, S. (1998b). A phase I/II dose-escalation study of herpes simplex virus type 1 thymidine kinase "suicide" gene therapy for metastatic melanoma. Study Group on Gene Therapy of Metastatic Melanoma. Hum. Gene Ther., 9: 2585-2594.
    • (1998) Hum. Gene Ther. , vol.9 , pp. 2585-2594
    • Klatzmann, D.1    Cherin, P.2    Bensimon, G.3    Boyer, O.4    Coutellier, A.5    Charlotte, F.6    Boccaccio, C.7    Salzmann, J.L.8    Herson, S.9
  • 141
    • 2442767029 scopus 로고    scopus 로고
    • A phase I/II study of herpes simplex virus type 1 thymidine kinase "suicide" gene therapy for recurrent glioblastoma
    • Study Group on Gene Therapy for Glioblastoma
    • Klatzmann, D., Valery, C.A., Bensimon, G., Marro, B., Boyer, O., Mokhtari, K., Diquet, B., Salzmann, J.L. and Philippon, J. (1998a). A phase I/II study of herpes simplex virus type 1 thymidine kinase "suicide" gene therapy for recurrent glioblastoma. Study Group on Gene Therapy for Glioblastoma. Hum. Gene Ther., 9: 2595-2604.
    • (1998) Hum. Gene Ther. , vol.9 , pp. 2595-2604
    • Klatzmann, D.1    Valery, C.A.2    Bensimon, G.3    Marro, B.4    Boyer, O.5    Mokhtari, K.6    Diquet, B.7    Salzmann, J.L.8    Philippon, J.9
  • 142
    • 0028287392 scopus 로고
    • Inhibition of metastasis of Lewis lung carcinoma by a synthetic peptide within growth factor-like domain of urokinase in the experimental and spontaneous metastasis model
    • Kobayashi, H., Gotoh, J., Fujie, M., Shinohara, H., Moniwa, N. and Terao, T. (1994). Inhibition of metastasis of Lewis lung carcinoma by a synthetic peptide within growth factor-like domain of urokinase in the experimental and spontaneous metastasis model. Int. J. Cancer, 57: 727-733.
    • (1994) Int. J. Cancer , vol.57 , pp. 727-733
    • Kobayashi, H.1    Gotoh, J.2    Fujie, M.3    Shinohara, H.4    Moniwa, N.5    Terao, T.6
  • 143
    • 0032053767 scopus 로고    scopus 로고
    • Signaling angiogenesis and lymphangiogenesis
    • Korpelainen, E.I. and Alitalo, K. (1998). Signaling angiogenesis and lymphangiogenesis. Curr. Opin. Cell Biol., 10: 159-164.
    • (1998) Curr. Opin. Cell Biol. , vol.10 , pp. 159-164
    • Korpelainen, E.I.1    Alitalo, K.2
  • 144
    • 0031913203 scopus 로고    scopus 로고
    • Characterization of an adenovirus vector containing a heterologous peptide epitope in the HI loop of the fiber knob
    • Krasnykh, V., Dmitriev, I., Mikheeva, G., Miller, C.R., Belousova, N. and Curiel, D.T. (1998). Characterization of an adenovirus vector containing a heterologous peptide epitope in the HI loop of the fiber knob. J. Virol., 72: 1844-1852.
    • (1998) J. Virol. , vol.72 , pp. 1844-1852
    • Krasnykh, V.1    Dmitriev, I.2    Mikheeva, G.3    Miller, C.R.4    Belousova, N.5    Curiel, D.T.6
  • 145
    • 0034623661 scopus 로고    scopus 로고
    • Immune effects and mechanisms of action of CpG motifs
    • Krieg, A.M. (2000). Immune effects and mechanisms of action of CpG motifs. Vaccine, 19: 618-622.
    • (2000) Vaccine , vol.19 , pp. 618-622
    • Krieg, A.M.1
  • 148
    • 0033805534 scopus 로고    scopus 로고
    • Selectivity of a replication-competent adenovirus for human breast carcinoma cells expressing the MUC1 antigen
    • Kurihara, T., Brough, D.E., Kovesdi, I. and Kufe, D.W. (2000). Selectivity of a replication-competent adenovirus for human breast carcinoma cells expressing the MUC1 antigen. J. Clin. Invest, 106: 763-771.
    • (2000) J. Clin. Invest , vol.106 , pp. 763-771
    • Kurihara, T.1    Brough, D.E.2    Kovesdi, I.3    Kufe, D.W.4
  • 149
    • 0037672877 scopus 로고    scopus 로고
    • Philadelphia chromosome-positive leukemias: From basic mechanisms to molecular therapeutics
    • Kurzrock, R., Kantarjian, H.M., Druker, B.J. and Talpaz, M. (2003). Philadelphia chromosome-positive leukemias: from basic mechanisms to molecular therapeutics. Ann. Intern. Med., 20;138: 819-830.
    • (2003) Ann. Intern. Med. , vol.138 , pp. 819-830
    • Kurzrock, R.1    Kantarjian, H.M.2    Druker, B.J.3    Talpaz, M.4
  • 152
    • 0033835016 scopus 로고    scopus 로고
    • A prospective phase II trial of ONYX-015 adenovirus and chemotherapy in recurrent squamous cell carcinoma of the head and neck (the Baylor experience)
    • Lamont, J.P., Nemunaitis, J., Kuhn, J.A., Landers, S.A. and McCarty, T.M. (2000). A prospective phase II trial of ONYX-015 adenovirus and chemotherapy in recurrent squamous cell carcinoma of the head and neck (the Baylor experience). Ann. Surg. Oncol., 7: 588-592.
    • (2000) Ann. Surg. Oncol. , vol.7 , pp. 588-592
    • Lamont, J.P.1    Nemunaitis, J.2    Kuhn, J.A.3    Landers, S.A.4    McCarty, T.M.5
  • 153
    • 0032704032 scopus 로고    scopus 로고
    • Adenovirus-mediated p53 gene therapy for human gliomas
    • Lang, F.F., Yung, W.K., Sawaya, R. and Tofilon, P.J. (1999). Adenovirus-mediated p53 gene therapy for human gliomas. Neurosurgery, 45: 1093-1104.
    • (1999) Neurosurgery , vol.45 , pp. 1093-1104
    • Lang, F.F.1    Yung, W.K.2    Sawaya, R.3    Tofilon, P.J.4
  • 157
    • 0029038135 scopus 로고
    • Apoptosis, cancer and the p53 tumour suppressor gene
    • Lee, J.M. and Bernstein, A. (1995). Apoptosis, cancer and the p53 tumour suppressor gene. Cancer Metastasis Rev., 14: 149-161.
    • (1995) Cancer Metastasis Rev. , vol.14 , pp. 149-161
    • Lee, J.M.1    Bernstein, A.2
  • 158
    • 0028233204 scopus 로고
    • Intravesical gene therapy: In vivo gene transfer using recombinant vaccinia virus vectors
    • Lee, S.S., Eisenlohr, L.C., McCue, P.A., Mastrangelo, M.J. and Lattime, E.C. (1994). Intravesical gene therapy: in vivo gene transfer using recombinant vaccinia virus vectors. Cancer Res., 54: 3325-3328.
    • (1994) Cancer Res. , vol.54 , pp. 3325-3328
    • Lee, S.S.1    Eisenlohr, L.C.2    McCue, P.A.3    Mastrangelo, M.J.4    Lattime, E.C.5
  • 161
  • 162
    • 0036521783 scopus 로고    scopus 로고
    • Trastuzumab: Hopes and realities
    • Leyland-Jones, B. (2002). Trastuzumab: hopes and realities. Lancet Oncol., 3: 137-144.
    • (2002) Lancet Oncol. , vol.3 , pp. 137-144
    • Leyland-Jones, B.1
  • 166
    • 0033532052 scopus 로고    scopus 로고
    • Systemic gene delivery expands the repertoire of effective antiangiogenic agents
    • Liu, Y., Thor, A., Shtivelman, E., Cao, Y., Tu, G., Heath, T.D. and Debs, R.J. (1999). Systemic gene delivery expands the repertoire of effective antiangiogenic agents. J. Biol. Chem., 274: 13338-13344.
    • (1999) J. Biol. Chem. , vol.274 , pp. 13338-13344
    • Liu, Y.1    Thor, A.2    Shtivelman, E.3    Cao, Y.4    Tu, G.5    Heath, T.D.6    Debs, R.J.7
  • 168
    • 0028103808 scopus 로고
    • A novel population of expanded human CD3+CD56+ cells derived from T cells with potent in vivo antitumor activity in mice with severe combined immunodeficiency
    • Lu, P.H. and Negrin, R.S. (1994). A novel population of expanded human CD3+CD56+ cells derived from T cells with potent in vivo antitumor activity in mice with severe combined immunodeficiency. J. Immunol., 153: 1687-1696.
    • (1994) J. Immunol. , vol.153 , pp. 1687-1696
    • Lu, P.H.1    Negrin, R.S.2
  • 169
    • 0035901089 scopus 로고    scopus 로고
    • Intralesional injection of herpes simplex virus 1716 in metastatic melanoma
    • MacKie, R.M., Stewart, B. and Brown, S.M. (2001). Intralesional injection of herpes simplex virus 1716 in metastatic melanoma. Lancet, 357: 525-526.
    • (2001) Lancet , vol.357 , pp. 525-526
    • MacKie, R.M.1    Stewart, B.2    Brown, S.M.3
  • 171
    • 0037314655 scopus 로고    scopus 로고
    • Phase II clinical trial of intralesional administration of the oncolytic adenovirus ONYX-015 in patients with hepatobiliary tumors with correlative p53 studies
    • Makower, D., Rozenblit, A., Kaufman, H., Edelman, M., Lane, M.E., Zwiebel, J., Haynes, H. and Wadler, S. (2003). Phase II clinical trial of intralesional administration of the oncolytic adenovirus ONYX-015 in patients with hepatobiliary tumors with correlative p53 studies. Clin. Cancer Res., 9: 693-702.
    • (2003) Clin. Cancer Res. , vol.9 , pp. 693-702
    • Makower, D.1    Rozenblit, A.2    Kaufman, H.3    Edelman, M.4    Lane, M.E.5    Zwiebel, J.6    Haynes, H.7    Wadler, S.8
  • 173
    • 0033579358 scopus 로고    scopus 로고
    • Clinical trials - Gene therapy death prompts review of adenovirus vector
    • Marshall, E. (1999). Clinical trials - Gene therapy death prompts review of adenovirus vector. Science, 286: 2244-2245.
    • (1999) Science , vol.286 , pp. 2244-2245
    • Marshall, E.1
  • 176
    • 0035523825 scopus 로고    scopus 로고
    • Cancer gene therapy: Fringe or cutting edge?
    • McCormick, F. (2001). Cancer gene therapy: fringe or cutting edge? Nat. Rev. Cancer, 1: 130-141.
    • (2001) Nat. Rev. Cancer , vol.1 , pp. 130-141
    • McCormick, F.1
  • 177
    • 0031727372 scopus 로고    scopus 로고
    • Histopathological responses in the CNS following inoculation with a non-neurovirulent mutant (1716) of herpes simplex virus type 1 (HSV 1): Relevance for gene and cancer therapy
    • McKie, E.A., Brown, S.M., MacLean, A.R. and Graham, D.I. (1998). Histopathological responses in the CNS following inoculation with a non-neurovirulent mutant (1716) of herpes simplex virus type 1 (HSV 1): relevance for gene and cancer therapy. Neuropathol. Appl. Neurobiol., 24: 367-372.
    • (1998) Neuropathol. Appl. Neurobiol. , vol.24 , pp. 367-372
    • McKie, E.A.1    Brown, S.M.2    MacLean, A.R.3    Graham, D.I.4
  • 178
    • 0033564483 scopus 로고    scopus 로고
    • Adoptive transfer of immature dendritic cells with autologous or allogeneic tumor cells generates systemic antitumor immunity
    • Melcher, A., Todryk, S., Bateman, A., Chong, H., Lemoine, N.R. and Vile, R.G. (1999). Adoptive transfer of immature dendritic cells with autologous or allogeneic tumor cells generates systemic antitumor immunity. Cancer Res., 59: 2802-2805.
    • (1999) Cancer Res. , vol.59 , pp. 2802-2805
    • Melcher, A.1    Todryk, S.2    Bateman, A.3    Chong, H.4    Lemoine, N.R.5    Vile, R.G.6
  • 179
    • 0029310528 scopus 로고
    • T-cell immunotherapy of tumors by adoptive transfer of cytotoxic T lymphocytes and by vaccination with minimal essential epitopes
    • Melief, C.J. and Kast, W.M. (1995). T-cell immunotherapy of tumors by adoptive transfer of cytotoxic T lymphocytes and by vaccination with minimal essential epitopes. Immunol. Rev., 145: 167-177.
    • (1995) Immunol. Rev. , vol.145 , pp. 167-177
    • Melief, C.J.1    Kast, W.M.2
  • 180
    • 0029996360 scopus 로고    scopus 로고
    • Bystander killing of cancer cells by herpes simplex virus thymidine kinase gene is mediated by connexins
    • Mesnil, M., Piccoli, C., Tiraby, G., Willecke, K. and Yamasaki, H. (1996). Bystander killing of cancer cells by herpes simplex virus thymidine kinase gene is mediated by connexins. Proc. Natl. Acad. Sci. USA, 93: 1831-1835.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 1831-1835
    • Mesnil, M.1    Piccoli, C.2    Tiraby, G.3    Willecke, K.4    Yamasaki, H.5
  • 182
    • 0033572553 scopus 로고    scopus 로고
    • Growth suppression of human ovarian cancer cells by adenovirus-mediated transfer of the PTEN gene
    • Minaguchi, T., Mori, T., Kanamori, Y., Matsushima, M., Yoshikawa, H., Taketani, Y. and Nakamura, Y. (1999). Growth suppression of human ovarian cancer cells by adenovirus-mediated transfer of the PTEN gene. Cancer Res., 59: 6063-6067.
    • (1999) Cancer Res. , vol.59 , pp. 6063-6067
    • Minaguchi, T.1    Mori, T.2    Kanamori, Y.3    Matsushima, M.4    Yoshikawa, H.5    Taketani, Y.6    Nakamura, Y.7
  • 183
    • 0029023868 scopus 로고
    • Attenuated multimutated herpes simplex virus-1 for the treatment of malignant gliomas
    • Mineta, T., Rabkin, S.D., Yazaki, T., Hunter, W.D. and Martuza, R.L. (1995). Attenuated multimutated herpes simplex virus-1 for the treatment of malignant gliomas. Nat. Med., 1: 938-943.
    • (1995) Nat. Med. , vol.1 , pp. 938-943
    • Mineta, T.1    Rabkin, S.D.2    Yazaki, T.3    Hunter, W.D.4    Martuza, R.L.5
  • 184
    • 0028702018 scopus 로고
    • Drug sensitivity ("suicide") genes for selective cancer chemotherapy
    • Moolten, F.L. (1994). Drug sensitivity ("suicide") genes for selective cancer chemotherapy. Cancer Gene Ther., 1: 279-287.
    • (1994) Cancer Gene Ther. , vol.1 , pp. 279-287
    • Moolten, F.L.1
  • 186
    • 0034159940 scopus 로고    scopus 로고
    • Gene therapy: The first decade
    • Mountain, A. (2000). Gene therapy: the first decade. Trends. Biotechnol., 18: 119-128.
    • (2000) Trends. Biotechnol. , vol.18 , pp. 119-128
    • Mountain, A.1
  • 187
    • 0025195542 scopus 로고
    • T-cell clones that react against autologous human tumors
    • Mukherji, B., Chakraborty, N.G. and Sivanandham, M. (1990). T-cell clones that react against autologous human tumors. Immunol. Rev., 116: 33-62.
    • (1990) Immunol. Rev. , vol.116 , pp. 33-62
    • Mukherji, B.1    Chakraborty, N.G.2    Sivanandham, M.3
  • 188
    • 0026599586 scopus 로고
    • Transfer of the bacterial gene for cytosine deaminase to mammalian cells confers lethal sensitivity to 5-fluorocytosine: A negative selection system
    • Mullen, C.A., Kilstrup, M. and Blaese, R.M. (1992). Transfer of the bacterial gene for cytosine deaminase to mammalian cells confers lethal sensitivity to 5-fluorocytosine: a negative selection system. Proc. Natl. Acad. Sci. USA, 89: 33-37.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 33-37
    • Mullen, C.A.1    Kilstrup, M.2    Blaese, R.M.3
  • 189
    • 0028297316 scopus 로고
    • Tumors expressing the cytosine deaminase suicide gene can be eliminated in vivo with 5-fluorocytosine and induce protective immunity to wild type tumor
    • Mullen, C.A., Coale, M.M., Lowe, R. and Blaese, R.M. (1994). Tumors expressing the cytosine deaminase suicide gene can be eliminated in vivo with 5-fluorocytosine and induce protective immunity to wild type tumor. Cancer Res., 54: 1503-1506.
    • (1994) Cancer Res. , vol.54 , pp. 1503-1506
    • Mullen, C.A.1    Coale, M.M.2    Lowe, R.3    Blaese, R.M.4
  • 190
    • 0035076823 scopus 로고    scopus 로고
    • Safety and feasibility of injection with an E1B-55 kDa gene-deleted, replication-selective adenovirus (ONYX-015) into primary carcinomas of the pancreas: A phase I trial
    • Mulvihill, S., Warren, R., Venook, A., Adler, A., Randlev, B., Heise, C. and Kirn, D. (2001). Safety and feasibility of injection with an E1B-55 kDa gene-deleted, replication-selective adenovirus (ONYX-015) into primary carcinomas of the pancreas: a phase I trial. Gene Therapy, 8: 308-315.
    • (2001) Gene Therapy , vol.8 , pp. 308-315
    • Mulvihill, S.1    Warren, R.2    Venook, A.3    Adler, A.4    Randlev, B.5    Heise, C.6    Kirn, D.7
  • 196
    • 0033693231 scopus 로고    scopus 로고
    • Selective replication and oncolysis in p53 mutant tumors with ONYX-015, an E1B-55kD gene-deleted adenovirus, in patients with advanced head and neck cancer: A phase II trial
    • Nemunaitis, J., Ganly, I., Khuri, F., Arseneau, J., Kuhn, J., McCarty, T., Landers, S., Maples, P., Romel, L., Randlev, B., Reid, T., Kaye, S. and Kirn, D. (2000a). Selective replication and oncolysis in p53 mutant tumors with ONYX-015, an E1B-55kD gene-deleted adenovirus, in patients with advanced head and neck cancer: a phase II trial. Cancer Res., 60: 6359-6366.
    • (2000) Cancer Res. , vol.60 , pp. 6359-6366
    • Nemunaitis, J.1    Ganly, I.2    Khuri, F.3    Arseneau, J.4    Kuhn, J.5    McCarty, T.6    Landers, S.7    Maples, P.8    Romel, L.9    Randlev, B.10    Reid, T.11    Kaye, S.12    Kirn, D.13
  • 200
    • 0032535405 scopus 로고    scopus 로고
    • Adeno-associated virus-mediated delivery of antiangiogenic factors as an antitumor strategy
    • Nguyen, J.T., Wu, P., Clouse, M.E., Hlatky, L. and Terwilliger, E.F. (1998). Adeno-associated virus-mediated delivery of antiangiogenic factors as an antitumor strategy. Cancer Res., 58: 5673-5677.
    • (1998) Cancer Res. , vol.58 , pp. 5673-5677
    • Nguyen, J.T.1    Wu, P.2    Clouse, M.E.3    Hlatky, L.4    Terwilliger, E.F.5
  • 201
    • 0036954247 scopus 로고    scopus 로고
    • Gene therapy progress and prospects: Nonviral vectors
    • Niidome, T. and Huang, L. (2002). Gene therapy progress and prospects: nonviral vectors. Gene Therapy, 9: 1647-1652.
    • (2002) Gene Therapy , vol.9 , pp. 1647-1652
    • Niidome, T.1    Huang, L.2
  • 202
    • 0033616597 scopus 로고    scopus 로고
    • RB-mediated suppression of spontaneous multiple neuroendocrine neoplasia and lung metastases in Rb+/- mice
    • Nikitin, A.Y., Juarez-Perez, M.I., Li, S., Huang, L. and Lee, W.H. (1999). RB-mediated suppression of spontaneous multiple neuroendocrine neoplasia and lung metastases in Rb+/- mice. Proc. Natl. Acad. Sci. USA, 96: 3916-3921.
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 3916-3921
    • Nikitin, A.Y.1    Juarez-Perez, M.I.2    Li, S.3    Huang, L.4    Lee, W.H.5
  • 204
  • 205
    • 0029944122 scopus 로고    scopus 로고
    • Angiostatin induces and sustains dormancy of human primary tumors in mice
    • O'Reilly, M.S., Holmgren, L., Chen, C. and Folkman, J. (1996). Angiostatin induces and sustains dormancy of human primary tumors in mice. Nat. Med., 2: 689-692.
    • (1996) Nat. Med. , vol.2 , pp. 689-692
    • O'Reilly, M.S.1    Holmgren, L.2    Chen, C.3    Folkman, J.4
  • 207
    • 0036202012 scopus 로고    scopus 로고
    • Rapid induction of specific cytotoxic T lymphocytes against melanoma-associated antigens by a recombinant vaccinia virus vector expressing multiple immunodominant epitopes and costimulatory molecules in vivo
    • Oertli, D., Marti, W.R., Zajac, P., Noppen, C., Kocher, T., Padovan, E., Adamina, M., Schumacher, R., Harder, F., Heberer, M. and Spagnoli, G.C. (2002). Rapid induction of specific cytotoxic T lymphocytes against melanoma-associated antigens by a recombinant vaccinia virus vector expressing multiple immunodominant epitopes and costimulatory molecules in vivo. Hum. Gene Ther., 13: 569-575.
    • (2002) Hum. Gene Ther. , vol.13 , pp. 569-575
    • Oertli, D.1    Marti, W.R.2    Zajac, P.3    Noppen, C.4    Kocher, T.5    Padovan, E.6    Adamina, M.7    Schumacher, R.8    Harder, F.9    Heberer, M.10    Spagnoli, G.C.11
  • 208
    • 0031854410 scopus 로고    scopus 로고
    • Chemotherapy in hepatocellular carcinoma
    • Okada, S. (1998). Chemotherapy in hepatocellular carcinoma. Hepatogastroenterology, 45 Suppl 3: 1259-1263.
    • (1998) Hepatogastroenterology , vol.45 , Issue.SUPPL. 3 , pp. 1259-1263
    • Okada, S.1
  • 210
    • 0033957146 scopus 로고    scopus 로고
    • Treatment of progressive or recurrent pediatric malignant supratentorial brain tumors with herpes simplex virus thymidine kinase gene vector-producer cells followed by intravenous ganciclovir administration
    • Packer, R.J., Raffel, C., Villablanca, J.G., Tonn, J.C., Burdach, S.E., Burger, K., LaFond, D., McComb, J.G., Cogen, P.H., Vezina, G. and Kapcala, L.P. (2000). Treatment of progressive or recurrent pediatric malignant supratentorial brain tumors with herpes simplex virus thymidine kinase gene vector-producer cells followed by intravenous ganciclovir administration. J. Neurosurg., 92: 249-254.
    • (2000) J. Neurosurg. , vol.92 , pp. 249-254
    • Packer, R.J.1    Raffel, C.2    Villablanca, J.G.3    Tonn, J.C.4    Burdach, S.E.5    Burger, K.6    LaFond, D.7    McComb, J.G.8    Cogen, P.H.9    Vezina, G.10    Kapcala, L.P.11
  • 212
  • 213
    • 0032553710 scopus 로고    scopus 로고
    • The search for the "best" cytokine to induce antitumor immunity
    • Paillard, F. (1998). The search for the "best" cytokine to induce antitumor immunity. Hum. Gene Ther., 20;9: 2457-2458.
    • (1998) Hum. Gene Ther. , vol.20 , Issue.9 , pp. 2457-2458
    • Paillard, F.1
  • 214
    • 0033022611 scopus 로고    scopus 로고
    • Genetic prodrug activation therapy for breast cancer: A phase I clinical trial of erbB-2-directed suicide gene expression
    • Pandha, H.S., Martin, L.A., Rigg, A., Hurst, H.C., Stamp, G.W., Sikora, K. and Lemoine, N.R. (1999). Genetic prodrug activation therapy for breast cancer: A phase I clinical trial of erbB-2-directed suicide gene expression. J. Clin. Oncol., 17: 2180-2189.
    • (1999) J. Clin. Oncol. , vol.17 , pp. 2180-2189
    • Pandha, H.S.1    Martin, L.A.2    Rigg, A.3    Hurst, H.C.4    Stamp, G.W.5    Sikora, K.6    Lemoine, N.R.7
  • 215
    • 0028908324 scopus 로고
    • Paracrine cytokine adjuvants in cancer immunotherapy
    • Pardoll, D.M. (1995). Paracrine cytokine adjuvants in cancer immunotherapy. Annu. Rev. Immunol., 13: 399-415.
    • (1995) Annu. Rev. Immunol. , vol.13 , pp. 399-415
    • Pardoll, D.M.1
  • 216
    • 0031960301 scopus 로고    scopus 로고
    • Cancer vaccines
    • Pardoll, D.M. (1998). Cancer vaccines. Nat. Med., 4: 525-531.
    • (1998) Nat. Med. , vol.4 , pp. 525-531
    • Pardoll, D.M.1
  • 217
    • 0033545982 scopus 로고    scopus 로고
    • Inducing autoimmune disease to treat cancer
    • Pardoll, D.M. (1999). Inducing autoimmune disease to treat cancer. Proc. Natl. Acad. Sci. USA, 96: 5340-5342.
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 5340-5342
    • Pardoll, D.M.1
  • 220
    • 0032541677 scopus 로고    scopus 로고
    • Tyrosine kinase receptor-activated signal transduction pathways which lead to oncogenesis
    • Porter, A.C. and Vaillancourt, R.R. (1998). Tyrosine kinase receptor-activated signal transduction pathways which lead to oncogenesis. Oncogene, 17: 1343-1352.
    • (1998) Oncogene , vol.17 , pp. 1343-1352
    • Porter, A.C.1    Vaillancourt, R.R.2
  • 221
    • 0026737950 scopus 로고
    • Accumulation of p53 protein correlates with a poor prognosis in human lung cancer
    • Quinlan, D.C., Davidson, A.G., Summers, C.L., Warden, H.E. and Doshi, H.M. (1992). Accumulation of p53 protein correlates with a poor prognosis in human lung cancer. Cancer Res., 52: 4828-4831.
    • (1992) Cancer Res. , vol.52 , pp. 4828-4831
    • Quinlan, D.C.1    Davidson, A.G.2    Summers, C.L.3    Warden, H.E.4    Doshi, H.M.5
  • 222
    • 0034694011 scopus 로고    scopus 로고
    • A phase III clinical evaluation of herpes simplex virus type 1 thymidine kinase and ganciclovir gene therapy as an adjuvant to surgical resection and radiation in adults with previously untreated glioblastoma multiforme
    • Rainov, N.G. (2000). A phase III clinical evaluation of herpes simplex virus type 1 thymidine kinase and ganciclovir gene therapy as an adjuvant to surgical resection and radiation in adults with previously untreated glioblastoma multiforme. Hum. Gene Ther., 20;11: 2389-2401.
    • (2000) Hum. Gene Ther. , vol.20 , Issue.11 , pp. 2389-2401
    • Rainov, N.G.1
  • 223
    • 0035974901 scopus 로고    scopus 로고
    • Virus-mediated killing of cells that lack p53 activity
    • Raj, K., Ogston, P. and Beard, P. (2001). Virus-mediated killing of cells that lack p53 activity. Nature, 412: 914-917.
    • (2001) Nature , vol.412 , pp. 914-917
    • Raj, K.1    Ogston, P.2    Beard, P.3
  • 225
    • 0000913758 scopus 로고    scopus 로고
    • Tumor killing using the HSV-tk suicide gene
    • T. Boulikas (Ed.), Gene Therapy Press, Palo Alto, CA
    • Ramesh, R., Marrogi, A.J. and Freeman, S.M. (1998). Tumor killing using the HSV-tk suicide gene. In: Gene Therapy and Molecular Biology, T. Boulikas (Ed.), Gene Therapy Press, Palo Alto, CA, pp. 253-263.
    • (1998) Gene Therapy and Molecular Biology , pp. 253-263
    • Ramesh, R.1    Marrogi, A.J.2    Freeman, S.M.3
  • 227
    • 0030914772 scopus 로고    scopus 로고
    • Treatment of experimental subcutaneous human melanoma with a replication-restricted herpes simplex virus mutant
    • Randazzo, B.P., Bhat, M.G., Kesari, S., Fraser, N.W. and Brown, S.M. (1997). Treatment of experimental subcutaneous human melanoma with a replication-restricted herpes simplex virus mutant. J. Invest Dermatol., 108: 933-937.
    • (1997) J. Invest Dermatol. , vol.108 , pp. 933-937
    • Randazzo, B.P.1    Bhat, M.G.2    Kesari, S.3    Fraser, N.W.4    Brown, S.M.5
  • 229
    • 0035177690 scopus 로고    scopus 로고
    • Intra-arterial administration of a replication-selective adenovirus (d11520) in patients with colorectal carcinoma metastatic to the liver: A phase I trial
    • Reid, T., Galanis, E., Abbruzzese, J., Sze, D., Andrews, J., Romel, L., Hatfield, M., Rubin, J. and Kirn, D. (2001). Intra-arterial administration of a replication-selective adenovirus (d11520) in patients with colorectal carcinoma metastatic to the liver: a phase I trial. Gene Therapy, 8: 1618-1626.
    • (2001) Gene Therapy , vol.8 , pp. 1618-1626
    • Reid, T.1    Galanis, E.2    Abbruzzese, J.3    Sze, D.4    Andrews, J.5    Romel, L.6    Hatfield, M.7    Rubin, J.8    Kirn, D.9
  • 231
    • 0032697619 scopus 로고    scopus 로고
    • Phase I study of direct intralesional gene transfer of HLA-B7 into metastatic renal carcinoma lesions
    • Rini, B.I., Selk, L.M. and Vogelzang, N.J. (1999). Phase I study of direct intralesional gene transfer of HLA-B7 into metastatic renal carcinoma lesions. Clin. Cancer Res., 5: 2766-2772.
    • (1999) Clin. Cancer Res. , vol.5 , pp. 2766-2772
    • Rini, B.I.1    Selk, L.M.2    Vogelzang, N.J.3
  • 232
    • 0035102821 scopus 로고    scopus 로고
    • Gene therapy of cancer
    • Rochlitz, C.F. (2001). Gene therapy of cancer. Swiss. Med. Wkly., 131: 4-9.
    • (2001) Swiss. Med. Wkly. , vol.131 , pp. 4-9
    • Rochlitz, C.F.1
  • 233
    • 0030790684 scopus 로고    scopus 로고
    • Prostate attenuated replication competent adenovirus (ARCA) CN706: A selective cytotoxic for prostate-specific antigen-positive prostate cancer cells
    • Rodriguez, R., Schuur, E.R., Lim, H.Y., Henderson, G.A., Simons, J.W. and Henderson, D.R. (1997). Prostate attenuated replication competent adenovirus (ARCA) CN706: a selective cytotoxic for prostate-specific antigen-positive prostate cancer cells. Cancer Res., 57: 2559-2563.
    • (1997) Cancer Res. , vol.57 , pp. 2559-2563
    • Rodriguez, R.1    Schuur, E.R.2    Lim, H.Y.3    Henderson, G.A.4    Simons, J.W.5    Henderson, D.R.6
  • 234
    • 0033984339 scopus 로고    scopus 로고
    • Double suicide gene therapy augments the antitumor activity of a replication-competent lytic adenovirus through enhanced cytotoxicity and radiosensitization
    • Rogulski, K.R., Wing, M.S., Paielli, D.L., Gilbert, J.D., Kim, J.H. and Freytag, S.O. (2000). Double suicide gene therapy augments the antitumor activity of a replication-competent lytic adenovirus through enhanced cytotoxicity and radiosensitization. Hum. Gene Ther., 11: 67-76.
    • (2000) Hum. Gene Ther. , vol.11 , pp. 67-76
    • Rogulski, K.R.1    Wing, M.S.2    Paielli, D.L.3    Gilbert, J.D.4    Kim, J.H.5    Freytag, S.O.6
  • 235
    • 0033974016 scopus 로고    scopus 로고
    • Latest developments in gene transfer technology: Achievements, perspectives, and controversies over therapeutic applications
    • Romano, G., Michell, P., Pacilio, C. and Giordano, A. (2000). Latest developments in gene transfer technology: achievements, perspectives, and controversies over therapeutic applications. Stem. Cells, 18: 19-39.
    • (2000) Stem. Cells , vol.18 , pp. 19-39
    • Romano, G.1    Michell, P.2    Pacilio, C.3    Giordano, A.4
  • 236
    • 0031424935 scopus 로고    scopus 로고
    • Keynote address: Perspectives on the use of interleukin-2 in cancer treatment
    • Rosenberg, S.A. (1997). Keynote address: perspectives on the use of interleukin-2 in cancer treatment. Cancer J. Sci. Am., 3: S2-S6.
    • (1997) Cancer J. Sci. Am. , vol.3
    • Rosenberg, S.A.1
  • 237
    • 0024988334 scopus 로고
    • Gene transfer into humans - Immunotherapy of patients with advanced melanoma, using tumor-infiltrating lymphocytes modified by retroviral gene transduction
    • Rosenberg, S.A., Aebersold, P., Cornetta, K., Kasid, A., Morgan, R.A., Moen, R., Karson, E.M., Lotze, M.T., Yang, J.C. and Topalian, S.L. (1990). Gene transfer into humans - immunotherapy of patients with advanced melanoma, using tumor-infiltrating lymphocytes modified by retroviral gene transduction. N. Engl. J. Med., 323: 570-578.
    • (1990) N. Engl. J. Med. , vol.323 , pp. 570-578
    • Rosenberg, S.A.1    Aebersold, P.2    Cornetta, K.3    Kasid, A.4    Morgan, R.A.5    Moen, R.6    Karson, E.M.7    Lotze, M.T.8    Yang, J.C.9    Topalian, S.L.10
  • 241
    • 0028991828 scopus 로고
    • Protection of retroviral vector particles in human blood through complement inhibition
    • Rother, R.P., Squinto, S.P., Mason, J.M. and Rollins, S.A. (1995). Protection of retroviral vector particles in human blood through complement inhibition. Hum. Gene Ther., 6: 429-435.
    • (1995) Hum. Gene Ther. , vol.6 , pp. 429-435
    • Rother, R.P.1    Squinto, S.P.2    Mason, J.M.3    Rollins, S.A.4
  • 242
    • 0037458826 scopus 로고    scopus 로고
    • Targeted cancer gene therapy: The flexibility of adenoviral gene therapy vectors
    • Rots, M.G., Curiel, D.T., Gerritsen, W.R. and Haisma, H.J. (2003). Targeted cancer gene therapy: the flexibility of adenoviral gene therapy vectors. J. Control Release, 87: 159-165.
    • (2003) J. Control Release , vol.87 , pp. 159-165
    • Rots, M.G.1    Curiel, D.T.2    Gerritsen, W.R.3    Haisma, H.J.4
  • 243
    • 0034744312 scopus 로고    scopus 로고
    • Epidemiological and molecular aspects of ovarian cancer risk
    • Runnebaum, I.B. and Stickeler, E. (2001). Epidemiological and molecular aspects of ovarian cancer risk. J. Cancer Res. Clin. Oncol., 127: 73-79.
    • (2001) J. Cancer Res. Clin. Oncol. , vol.127 , pp. 73-79
    • Runnebaum, I.B.1    Stickeler, E.2
  • 244
    • 0036905014 scopus 로고    scopus 로고
    • RNA viruses as virotherapy agents
    • Russell, S.J. (2002). RNA viruses as virotherapy agents. Cancer Gene Ther., 9: 961-966.
    • (2002) Cancer Gene Ther. , vol.9 , pp. 961-966
    • Russell, S.J.1
  • 245
    • 0029766528 scopus 로고    scopus 로고
    • Carcinoma cell lines become sensitive to DNA-damaging agents by the expression of the adenovirus E1A gene
    • Sanchez-Prieto, R., Quintanilla, M., Cano, A., Leonart, M.L., Martin, P., Anaya, A. and Cajal, S. (1996). Carcinoma cell lines become sensitive to DNA-damaging agents by the expression of the adenovirus E1A gene. Oncogene, 13: 1083-1092.
    • (1996) Oncogene , vol.13 , pp. 1083-1092
    • Sanchez-Prieto, R.1    Quintanilla, M.2    Cano, A.3    Leonart, M.L.4    Martin, P.5    Anaya, A.6    Cajal, S.7
  • 247
    • 0034128036 scopus 로고    scopus 로고
    • Herpes simplex virus thymidine kinase gene therapy in experimental rat BT4C glioma model: Effect of the percentage of thymidine kinase-positive glioma cells on treatment effect, survival time, and tissue reactions
    • Sandmair, A.M., Turunen, M., Tyynela, K., Loimas, S., Vainio, P., Vanninen, R., Vapalahti, M., Bjerkvig, R., Janne, J. and Yla-Herttuala, S. (2000a). Herpes simplex virus thymidine kinase gene therapy in experimental rat BT4C glioma model: effect of the percentage of thymidine kinase-positive glioma cells on treatment effect, survival time, and tissue reactions. Cancer Gene Ther., 7: 413-421.
    • (2000) Cancer Gene Ther. , vol.7 , pp. 413-421
    • Sandmair, A.M.1    Turunen, M.2    Tyynela, K.3    Loimas, S.4    Vainio, P.5    Vanninen, R.6    Vapalahti, M.7    Bjerkvig, R.8    Janne, J.9    Yla-Herttuala, S.10
  • 248
    • 0032160033 scopus 로고    scopus 로고
    • Complex role of matrix metalloproteinases in angiogenesis
    • Sang, Q.X. (1998). Complex role of matrix metalloproteinases in angiogenesis. Cell Res., 8: 171-177.
    • (1998) Cell Res. , vol.8 , pp. 171-177
    • Sang, Q.X.1
  • 249
    • 0033570910 scopus 로고    scopus 로고
    • Structural basis and potential role of heparin/heparan sulfate binding to the angiogenesis inhibitor endostatin
    • Sasaki, T., Larsson, H., Kreuger, J., Salmivirta, M., Claesson-Welsh, L., Lindahl, U., Hohenester, E. and Timpl, R. (1999). Structural basis and potential role of heparin/heparan sulfate binding to the angiogenesis inhibitor endostatin. EMBO J., 18: 6240-6248.
    • (1999) EMBO J. , vol.18 , pp. 6240-6248
    • Sasaki, T.1    Larsson, H.2    Kreuger, J.3    Salmivirta, M.4    Claesson-Welsh, L.5    Lindahl, U.6    Hohenester, E.7    Timpl, R.8
  • 250
    • 0028856771 scopus 로고
    • Interleukin-7, interleukin-12, and GM-CSF gene transfer in patients with metastatic melanoma
    • Schadendorf, D., Czarnetzki, B.M. and Wittig, B. (1995). Interleukin-7, interleukin-12, and GM-CSF gene transfer in patients with metastatic melanoma. J. Mol. Med., 73: 473-477.
    • (1995) J. Mol. Med. , vol.73 , pp. 473-477
    • Schadendorf, D.1    Czarnetzki, B.M.2    Wittig, B.3
  • 252
    • 0034997403 scopus 로고    scopus 로고
    • Non-viral vectors in cancer gene therapy: Principles and progress
    • Schatzlein, A.G. (2001). Non-viral vectors in cancer gene therapy: principles and progress. Anticancer Drugs, 12: 275-304.
    • (2001) Anticancer Drugs , vol.12 , pp. 275-304
    • Schatzlein, A.G.1
  • 253
    • 0037298141 scopus 로고    scopus 로고
    • New directions for ZD1839 in the treatment of solid tumors
    • Schiller, J.H. (2003). New directions for ZD1839 in the treatment of solid tumors. Semin. Oncol., 30: 49-55.
    • (2003) Semin. Oncol. , vol.30 , pp. 49-55
    • Schiller, J.H.1
  • 254
    • 0025856106 scopus 로고
    • Use of a SCID mouse/human lymphoma model to evaluate cytokine-induced killer cells with potent antitumor cell activity
    • Schmidt-Wolf, I.G., Negrin, R.S., Kiem, H.P., Blume, K.G. and Weissman, I.L. (1991). Use of a SCID mouse/human lymphoma model to evaluate cytokine-induced killer cells with potent antitumor cell activity. J. Exp. Med, 174: 139-149.
    • (1991) J. Exp. Med , vol.174 , pp. 139-149
    • Schmidt-Wolf, I.G.1    Negrin, R.S.2    Kiem, H.P.3    Blume, K.G.4    Weissman, I.L.5
  • 258
    • 0033588816 scopus 로고    scopus 로고
    • A phase 1-2 clinical trial of gene therapy for recurrent glioblastoma multiforme by tumor transduction with the herpes simplex thymidine kinase gene followed by ganciclovir
    • GLI328 European-Canadian Study Group
    • Shand, N., Weber, F., Mariani, L., Bernstein, M., Gianella-Borradori, A., Long, Z., Sorensen, A.G. and Barbier, N. (1999). A phase 1-2 clinical trial of gene therapy for recurrent glioblastoma multiforme by tumor transduction with the herpes simplex thymidine kinase gene followed by ganciclovir. GLI328 European-Canadian Study Group. Hum. Gene Ther., 20;10: 2325-2335.
    • (1999) Hum. Gene Ther. , vol.20 , Issue.10 , pp. 2325-2335
    • Shand, N.1    Weber, F.2    Mariani, L.3    Bernstein, M.4    Gianella-Borradori, A.5    Long, Z.6    Sorensen, A.G.7    Barbier, N.8
  • 259
    • 0029948779 scopus 로고    scopus 로고
    • Induction of apoptosis by the tumor suppressor protein BRCAI
    • Shao, N., Chai, Y.L., Shyam, E., Reddy, P. and Rao, V.N. (1996). Induction of apoptosis by the tumor suppressor protein BRCAI. Oncogene, 13: 1-7.
    • (1996) Oncogene , vol.13 , pp. 1-7
    • Shao, N.1    Chai, Y.L.2    Shyam, E.3    Reddy, P.4    Rao, V.N.5
  • 260
    • 0031884723 scopus 로고    scopus 로고
    • Biology and treatment of malignant glioma
    • Shapiro, W.R. and Shapiro, J.R. (1998). Biology and treatment of malignant glioma. Oncology (Huntingt.), 12: 233-240.
    • (1998) Oncology (Huntingt.) , vol.12 , pp. 233-240
    • Shapiro, W.R.1    Shapiro, J.R.2
  • 263
    • 37049183697 scopus 로고
    • Human breast cancer: Correlation of relapse and survival with amplification of the HER-2/neu oncogene
    • Slamon, D.J., Clark, G.M., Wong, S.G., Levin, W.J., Ullrich, A. and McGuire, W.L. (1987). Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene. Science, 235: 177-182.
    • (1987) Science , vol.235 , pp. 177-182
    • Slamon, D.J.1    Clark, G.M.2    Wong, S.G.3    Levin, W.J.4    Ullrich, A.5    McGuire, W.L.6
  • 265
    • 0026325974 scopus 로고
    • Cutaneous melanoma: Opportunity for cure
    • Sober, A.J. (1991). Cutaneous melanoma: opportunity for cure. CA Cancer J. Clin., 41: 197-199.
    • (1991) CA Cancer J. Clin. , vol.41 , pp. 197-199
    • Sober, A.J.1
  • 268
    • 0034328925 scopus 로고    scopus 로고
    • Gene therapy: Trials and tribulations
    • Somia, N. and Verma, I.M. (2000). Gene therapy: trials and tribulations. Nat. Rev. Genet., 1: 91-99.
    • (2000) Nat. Rev. Genet. , vol.1 , pp. 91-99
    • Somia, N.1    Verma, I.M.2
  • 269
    • 0023139735 scopus 로고
    • Activation of human raf transforming genes by deletion of normal amino-terminal coding sequences
    • Stanton, V.P. and Cooper, G.M. (1987). Activation of human raf transforming genes by deletion of normal amino-terminal coding sequences. Mol. Cell Biol., 7: 1171-1179.
    • (1987) Mol. Cell Biol. , vol.7 , pp. 1171-1179
    • Stanton, V.P.1    Cooper, G.M.2
  • 270
    • 17344365922 scopus 로고    scopus 로고
    • Adenovirus-mediated herpes simplex virus thymidine kinase/ganciclovir gene therapy in patients with localized malignancy: Results of a phase I clinical trial in malignant mesothelioma
    • Sterman, D.H., Treat, J., Litzky, L.A., Amin, K.M., Coonrod, L., Molnar-Kimber, K., Recio, A., Knox, L., Wilson, J.M., Albelda, S.M. and Kaiser, L.R. (1998). Adenovirus-mediated herpes simplex virus thymidine kinase/ganciclovir gene therapy in patients with localized malignancy: results of a phase I clinical trial in malignant mesothelioma. Hum. Gene Ther., 9: 1083-1092.
    • (1998) Hum. Gene Ther. , vol.9 , pp. 1083-1092
    • Sterman, D.H.1    Treat, J.2    Litzky, L.A.3    Amin, K.M.4    Coonrod, L.5    Molnar-Kimber, K.6    Recio, A.7    Knox, L.8    Wilson, J.M.9    Albelda, S.M.10    Kaiser, L.R.11
  • 273
    • 0034885426 scopus 로고    scopus 로고
    • Phase II study of direct intralesional gene transfer of allovectin-7, an HLA-B7/beta2-microglobulin DNA-liposome complex, in patients with metastatic melanoma
    • Stopeck, A.T., Jones, A., Hersh, E.M., Thompson, J.A., Finucane, D.M., Gutheil, J.C. and Gonzalez, R. (2001). Phase II study of direct intralesional gene transfer of allovectin-7, an HLA-B7/beta2-microglobulin DNA-liposome complex, in patients with metastatic melanoma. Clin. Cancer Res., 7: 2285-2291.
    • (2001) Clin. Cancer Res. , vol.7 , pp. 2285-2291
    • Stopeck, A.T.1    Jones, A.2    Hersh, E.M.3    Thompson, J.A.4    Finucane, D.M.5    Gutheil, J.C.6    Gonzalez, R.7
  • 275
    • 0032526693 scopus 로고    scopus 로고
    • The molecular basis of viral oncolysis: Usurpation of the Ras signaling pathway by reovirus
    • Strong, J.E., Coffey, M.C., Tang, D., Sabinin, P. and Lee, P.W. (1998). The molecular basis of viral oncolysis: usurpation of the Ras signaling pathway by reovirus. EMBO J., 17: 3351-3362.
    • (1998) EMBO J. , vol.17 , pp. 3351-3362
    • Strong, J.E.1    Coffey, M.C.2    Tang, D.3    Sabinin, P.4    Lee, P.W.5
  • 276
    • 0034035628 scopus 로고    scopus 로고
    • Attenuated, replication-competent herpes simplex virus type 1 mutant
    • Sundaresan, P., Hunter, W.D., Martuza, R.L. and Rabkin, S.D. (2000). Attenuated, replication-competent herpes simplex virus type 1 mutant G207: safety evaluation in mice. J. Virol., 74: 3832-3841.
    • (2000) J. Virol. , vol.74 , pp. 3832-3841
    • Sundaresan, P.1    Hunter, W.D.2    Martuza, R.L.3    Rabkin, S.D.4
  • 277
    • 0034841686 scopus 로고    scopus 로고
    • Intratumoral adenovirus-mediated suicide gene transfer for hepatic metastases from colorectal adenocarcinoma: Results of a phase I clinical trial
    • Sung, M.W., Yeh, H.C., Thung, S.N., Schwartz, M.E., Mandeli, J.P., Chen, S.H. and Woo, S.L. (2001). Intratumoral adenovirus-mediated suicide gene transfer for hepatic metastases from colorectal adenocarcinoma: results of a phase I clinical trial. Mol. Ther., 4: 182-191.
    • (2001) Mol. Ther. , vol.4 , pp. 182-191
    • Sung, M.W.1    Yeh, H.C.2    Thung, S.N.3    Schwartz, M.E.4    Mandeli, J.P.5    Chen, S.H.6    Woo, S.L.7
  • 280
    • 0034220882 scopus 로고    scopus 로고
    • Radiation-induced apoptosis: Predictive and therapeutic significance in radiotherapy of prostate cancer
    • Szostak, M.J. and Kyprianou, N. (2000). Radiation-induced apoptosis: predictive and therapeutic significance in radiotherapy of prostate cancer (review). Oncol. Rep., 7: 699-706.
    • (2000) Oncol. Rep. , vol.7 , pp. 699-706
    • Szostak, M.J.1    Kyprianou, N.2
  • 282
    • 0032790963 scopus 로고    scopus 로고
    • Ovarian cancer BRCA1 gene therapy: Phase I and II trial differences in immune response and vector stability
    • Tait, D.L., Obermiller, P.S., Hatmaker, A.R., Redlin-Frazier, S. and Holt, J.T. (1999). Ovarian cancer BRCA1 gene therapy: Phase I and II trial differences in immune response and vector stability. Clin. Cancer Res., 5: 1708-1714.
    • (1999) Clin. Cancer Res. , vol.5 , pp. 1708-1714
    • Tait, D.L.1    Obermiller, P.S.2    Hatmaker, A.R.3    Redlin-Frazier, S.4    Holt, J.T.5
  • 283
    • 0033664785 scopus 로고    scopus 로고
    • Preclinical studies of a new generation retroviral vector for ovarian cancer BRCA1 gene therapy
    • Tait, D.L., Obermiller, P.S. and Holt, J.T. (2000). Preclinical studies of a new generation retroviral vector for ovarian cancer BRCA1 gene therapy. Gynecol. Oncol., 79: 471-476.
    • (2000) Gynecol. Oncol. , vol.79 , pp. 471-476
    • Tait, D.L.1    Obermiller, P.S.2    Holt, J.T.3
  • 285
    • 0034655246 scopus 로고    scopus 로고
    • Suppression of tumor angiogenesis and growth by gene transfer of a soluble form of vascular endothelial growth factor receptor into a remote organ
    • Takayama, K., Ueno, H., Nakanishi, Y., Sakamoto, T., Inoue, K., Shimizu, K., Oohashi, H. and Hara, N. (2000). Suppression of tumor angiogenesis and growth by gene transfer of a soluble form of vascular endothelial growth factor receptor into a remote organ. Cancer Res., 60: 2169-2177.
    • (2000) Cancer Res. , vol.60 , pp. 2169-2177
    • Takayama, K.1    Ueno, H.2    Nakanishi, Y.3    Sakamoto, T.4    Inoue, K.5    Shimizu, K.6    Oohashi, H.7    Hara, N.8
  • 286
    • 0034626708 scopus 로고    scopus 로고
    • MMAC1/PTEN inhibits cell growth and induces chemosensitivity to doxorubicin in human bladder cancer cells
    • Tanaka, M., Koul, D., Davies, M.A., Liebert, M., Steck, P.A. and Grossman, H.B. (2000). MMAC1/PTEN inhibits cell growth and induces chemosensitivity to doxorubicin in human bladder cancer cells. Oncogene, 19: 5406-5412.
    • (2000) Oncogene , vol.19 , pp. 5406-5412
    • Tanaka, M.1    Koul, D.2    Davies, M.A.3    Liebert, M.4    Steck, P.A.5    Grossman, H.B.6
  • 287
    • 0032145376 scopus 로고    scopus 로고
    • Viral vector-targeted antiangiogenic gene therapy utilizing an angiostatin complementary DNA
    • Tanaka, T., Cao, Y., Folkman, J. and Fine, H.A. (1998). Viral vector-targeted antiangiogenic gene therapy utilizing an angiostatin complementary DNA. Cancer Res., 58: 3362-3369.
    • (1998) Cancer Res. , vol.58 , pp. 3362-3369
    • Tanaka, T.1    Cao, Y.2    Folkman, J.3    Fine, H.A.4
  • 288
    • 0031667546 scopus 로고    scopus 로고
    • Targeting angiogenesis: Genetic intervention which strikes at the weak link of tumorigenesis
    • Taniguchi, T., Rigg, A. and Lemoine, N.R. (1998). Targeting angiogenesis: genetic intervention which strikes at the weak link of tumorigenesis. Gene Therapy, 5: 1011-1013.
    • (1998) Gene Therapy , vol.5 , pp. 1011-1013
    • Taniguchi, T.1    Rigg, A.2    Lemoine, N.R.3
  • 292
    • 0038574350 scopus 로고    scopus 로고
    • Non-viral gene therapy: Polycation-mediated DNA delivery
    • Thomas, M. and Klibanov, A.M. (2003). Non-viral gene therapy: polycation-mediated DNA delivery. Appl. Microbiol. Biotechnol., 62: 27-34.
    • (2003) Appl. Microbiol. Biotechnol. , vol.62 , pp. 27-34
    • Thomas, M.1    Klibanov, A.M.2
  • 293
    • 0032020501 scopus 로고    scopus 로고
    • Local inflammatory response and vector spread after direct intraprostatic injection of a recombinant adenovirus containing the herpes simplex virus thymidine kinase gene and ganciclovir therapy in mice
    • Timme, T.L., Hall, S.J., Barrios, R., Woo, S.L., Aguilar-Cordova, E. and Thompson, T.C. (1998). Local inflammatory response and vector spread after direct intraprostatic injection of a recombinant adenovirus containing the herpes simplex virus thymidine kinase gene and ganciclovir therapy in mice. Cancer Gene Ther., 5: 74-82.
    • (1998) Cancer Gene Ther. , vol.5 , pp. 74-82
    • Timme, T.L.1    Hall, S.J.2    Barrios, R.3    Woo, S.L.4    Aguilar-Cordova, E.5    Thompson, T.C.6
  • 294
    • 0035026010 scopus 로고    scopus 로고
    • Novel compounds in the therapy of breast cancer: Opportunities for integration with docetaxel
    • Tolcher, A.W. (2001). Novel compounds in the therapy of breast cancer: opportunities for integration with docetaxel. Oncologist., 6 Suppl 3: 40-44.
    • (2001) Oncologist. , vol.6 , Issue.SUPPL. 3 , pp. 40-44
    • Tolcher, A.W.1
  • 295
    • 0036023413 scopus 로고    scopus 로고
    • A randomized phase II and pharmacokinetic study of the antisense oligonucleotides ISIS 3521 and ISIS 5132 in patients with hormone-refractory prostate cancer
    • Tolcher, A.W., Reyno, L., Venner, P.M., Ernst, S.D., Moore, M., Geary, R.S., Chi, K., Hall, S., Walsh, W., Dorr, A. and Eisenhauer, E. (2002). A randomized phase II and pharmacokinetic study of the antisense oligonucleotides ISIS 3521 and ISIS 5132 in patients with hormone-refractory prostate cancer. Clin. Cancer Res., 8: 2530-2535.
    • (2002) Clin. Cancer Res. , vol.8 , pp. 2530-2535
    • Tolcher, A.W.1    Reyno, L.2    Venner, P.M.3    Ernst, S.D.4    Moore, M.5    Geary, R.S.6    Chi, K.7    Hall, S.8    Walsh, W.9    Dorr, A.10    Eisenhauer, E.11
  • 297
    • 0021237051 scopus 로고
    • The biology and treatment of superficial bladder cancer
    • Torti, F.M. and Lum, B.L. (1984). The biology and treatment of superficial bladder cancer. J. Clin. Oncol., 2: 505-531.
    • (1984) J. Clin. Oncol. , vol.2 , pp. 505-531
    • Torti, F.M.1    Lum, B.L.2
  • 298
    • 0038616094 scopus 로고    scopus 로고
    • Gene therapy for hepatocellular carcinoma using non-viral vectors composed of bis guanidinium-tren-cholesterol and plasmids encoding the tissue inhibitors of metalloproteinases TIMP-2 and TIMP-3
    • Tran, P.L., Vigneron, J.P., Pericat, D., Dubois, S., Cazals, D., Hervy, M., DeClerck, Y.A., Degott, C. and Auclair, C. (2003). Gene therapy for hepatocellular carcinoma using non-viral vectors composed of bis guanidinium-tren-cholesterol and plasmids encoding the tissue inhibitors of metalloproteinases TIMP-2 and TIMP-3. Cancer Gene Ther., 10: 435-444.
    • (2003) Cancer Gene Ther. , vol.10 , pp. 435-444
    • Tran, P.L.1    Vigneron, J.P.2    Pericat, D.3    Dubois, S.4    Cazals, D.5    Hervy, M.6    DeClerck, Y.A.7    Degott, C.8    Auclair, C.9
  • 302
    • 0037087621 scopus 로고    scopus 로고
    • Phase I trial of intraperitoneal injection of the E1B-55-kd-gene-deleted adenovirus ONYX-015 (d11520) given on days 1 through 5 every 3 weeks in patients with recurrent/refractory epithelial ovarian cancer
    • Vasey, P.A., Shulman, L.N., Campos, S., Davis, J., Gore, M., Johnston, S., Kirn, D.H., O'Neill, V., Siddiqui, N., Seiden, M.V. and Kaye, S.B. (2002). Phase I trial of intraperitoneal injection of the E1B-55-kd-gene-deleted adenovirus ONYX-015 (d11520) given on days 1 through 5 every 3 weeks in patients with recurrent/refractory epithelial ovarian cancer. J. Clin. Oncol., 20: 1562-1569.
    • (2002) J. Clin. Oncol. , vol.20 , pp. 1562-1569
    • Vasey, P.A.1    Shulman, L.N.2    Campos, S.3    Davis, J.4    Gore, M.5    Johnston, S.6    Kirn, D.H.7    O'Neill, V.8    Siddiqui, N.9    Seiden, M.V.10    Kaye, S.B.11
  • 303
    • 2542554962 scopus 로고    scopus 로고
    • Simian virus-40 as a gene therapy vector
    • Vera, M. and Fortes, P. (2004). Simian virus-40 as a gene therapy vector. DNA Cell Biol., 23: 271-282.
    • (2004) DNA Cell Biol. , vol.23 , pp. 271-282
    • Vera, M.1    Fortes, P.2
  • 304
    • 0030928619 scopus 로고    scopus 로고
    • Gene therapy - Promises, problems and prospects
    • Verma, I.M. and Somia, N. (1997). Gene therapy - promises, problems and prospects [news]. Nature, 389: 239-242.
    • (1997) Nature , vol.389 , pp. 239-242
    • Verma, I.M.1    Somia, N.2
  • 305
    • 0028926021 scopus 로고
    • Retroviruses as vectors
    • Vile, R.G. and Russell, S.J. (1995). Retroviruses as vectors. Br. Med. Bull., 51: 12-30.
    • (1995) Br. Med. Bull. , vol.51 , pp. 12-30
    • Vile, R.G.1    Russell, S.J.2
  • 306
    • 0033959447 scopus 로고    scopus 로고
    • Cancer gene therapy: Hard lessons and new courses
    • Vile, R.G., Russell, S.J. and Lemoine, N.R. (2000). Cancer gene therapy: hard lessons and new courses. Gene Therapy, 7: 2-8.
    • (2000) Gene Therapy , vol.7 , pp. 2-8
    • Vile, R.G.1    Russell, S.J.2    Lemoine, N.R.3
  • 307
    • 0036303883 scopus 로고    scopus 로고
    • A multicenter phase II study of tgDCC-E1A for the intratumoral treatment of patients with recurrent head and neck squamous cell carcinoma
    • Villaret, D., Glisson, B., Kenady, D., Hanna, E., Carey, M., Gleich, L., Yoo, G.H., Futran, N., Hung, M.C., Anklesaria, P. and Heald, A.E. (2002). A multicenter phase II study of tgDCC-E1A for the intratumoral treatment of patients with recurrent head and neck squamous cell carcinoma. Head Neck, 24: 661-669.
    • (2002) Head Neck , vol.24 , pp. 661-669
    • Villaret, D.1    Glisson, B.2    Kenady, D.3    Hanna, E.4    Carey, M.5    Gleich, L.6    Yoo, G.H.7    Futran, N.8    Hung, M.C.9    Anklesaria, P.10    Heald, A.E.11
  • 308
    • 0030757097 scopus 로고    scopus 로고
    • The bystander effect exerted by tumor cells expressing the herpes simplex virus thymidine kinase (HSVtk) gene is dependent on connexin expression and cell communication via gap junctions
    • Vrionis, F.D., Wu, J.K., Qi, P., Waltzman, M., Cherington, V. and Spray, D.C. (1997). The bystander effect exerted by tumor cells expressing the herpes simplex virus thymidine kinase (HSVtk) gene is dependent on connexin expression and cell communication via gap junctions. Gene Therapy, 4: 577-585.
    • (1997) Gene Therapy , vol.4 , pp. 577-585
    • Vrionis, F.D.1    Wu, J.K.2    Qi, P.3    Waltzman, M.4    Cherington, V.5    Spray, D.C.6
  • 310
    • 0033591429 scopus 로고    scopus 로고
    • Cloning genes encoding MHC class II-restricted antigens: Mutated CDC27 as a tumor antigen
    • Wang, R.F., Wang, X., Atwood, A.C., Topalian, S.L. and Rosenberg, S.A. (1999a). Cloning genes encoding MHC class II-restricted antigens: mutated CDC27 as a tumor antigen. Science, 284: 1351-1354.
    • (1999) Science , vol.284 , pp. 1351-1354
    • Wang, R.F.1    Wang, X.2    Atwood, A.C.3    Topalian, S.L.4    Rosenberg, S.A.5
  • 311
    • 0033577804 scopus 로고    scopus 로고
    • Identification of a novel major histocompatibility complex class II-restricted tumor antigen resulting from a chromosomal rearrangement recognized by CD4(+) T cells
    • Wang, R.F., Wang, X. and Rosenberg, S.A. (1999b). Identification of a novel major histocompatibility complex class II-restricted tumor antigen resulting from a chromosomal rearrangement recognized by CD4(+) T cells. J. Exp. Med., 189: 1659-1668.
    • (1999) J. Exp. Med. , vol.189 , pp. 1659-1668
    • Wang, R.F.1    Wang, X.2    Rosenberg, S.A.3
  • 313
    • 0031861077 scopus 로고    scopus 로고
    • Surgical management of local and regional recurrent head and neck squamous cell carcinoma
    • Watson, J.C. and Ridge, J.A. (1998). Surgical management of local and regional recurrent head and neck squamous cell carcinoma. Curr. Opin. Oncol., 10: 207-212.
    • (1998) Curr. Opin. Oncol. , vol.10 , pp. 207-212
    • Watson, J.C.1    Ridge, J.A.2
  • 315
    • 0033785831 scopus 로고    scopus 로고
    • Adenoviral-mediated p53 gene transfer to non-small cell lung cancer through endobronchial injection
    • Weill, D., Mack, M., Roth, J., Swisher, S., Proksch, S., Merritt, J. and Nemunaitis, J. (2000). Adenoviral-mediated p53 gene transfer to non-small cell lung cancer through endobronchial injection. Chest, 118: 966-970.
    • (2000) Chest , vol.118 , pp. 966-970
    • Weill, D.1    Mack, M.2    Roth, J.3    Swisher, S.4    Proksch, S.5    Merritt, J.6    Nemunaitis, J.7
  • 316
    • 0028991824 scopus 로고
    • Bacterial lipopolysaccharide copurifies with plasmid DNA: Implications for animal models and human gene therapy
    • Wicks, I.P., Howell, M.L., Hancock, T., Kohsaka, H., Olee, T. and Carson, D.A. (1995). Bacterial lipopolysaccharide copurifies with plasmid DNA: implications for animal models and human gene therapy. Hum. Gene Ther., 6: 317-323.
    • (1995) Hum. Gene Ther. , vol.6 , pp. 317-323
    • Wicks, I.P.1    Howell, M.L.2    Hancock, T.3    Kohsaka, H.4    Olee, T.5    Carson, D.A.6
  • 317
    • 0026342978 scopus 로고
    • Response of prostate cancer cells to peptide growth factors: Transforming growth factor-beta
    • Wilding, G. (1991). Response of prostate cancer cells to peptide growth factors: transforming growth factor-beta. Cancer Surv., 11: 147-163.
    • (1991) Cancer Surv. , vol.11 , pp. 147-163
    • Wilding, G.1
  • 318
    • 0033556003 scopus 로고    scopus 로고
    • Therapy of colon cancer with oncolytic adenovirus is enhanced by the addition of herpes simplex virus-thymidine kinase
    • Wildner, O., Blaese, R.M. and Morris, J.C. (1999). Therapy of colon cancer with oncolytic adenovirus is enhanced by the addition of herpes simplex virus-thymidine kinase. Cancer Res., 59: 410-413.
    • (1999) Cancer Res. , vol.59 , pp. 410-413
    • Wildner, O.1    Blaese, R.M.2    Morris, J.C.3
  • 319
    • 0009989827 scopus 로고    scopus 로고
    • Results of a randomized phase III trial of sequential intravesical therapy with mitomycin C and bacillus Calmette-Guerin versus mitomycin C alone in patients with superficial bladder cancer
    • Witjes, J.A., Caris, C.T., Mungan, N.A., Debruyne, F.M. and Witjes, W.P. (1998). Results of a randomized phase III trial of sequential intravesical therapy with mitomycin C and bacillus Calmette-Guerin versus mitomycin C alone in patients with superficial bladder cancer. J. Urol., 160: 1668-1671.
    • (1998) J. Urol. , vol.160 , pp. 1668-1671
    • Witjes, J.A.1    Caris, C.T.2    Mungan, N.A.3    Debruyne, F.M.4    Witjes, W.P.5
  • 321
    • 0017172793 scopus 로고
    • A retrospective study of the natural history of patients with liver metastases from colorectal cancer
    • Wood, C.B., Gillis, C.R. and Blumgart, L.H. (1976). A retrospective study of the natural history of patients with liver metastases from colorectal cancer. Clin. Oncol., 2: 285-288.
    • (1976) Clin. Oncol. , vol.2 , pp. 285-288
    • Wood, C.B.1    Gillis, C.R.2    Blumgart, L.H.3
  • 324
    • 0028095020 scopus 로고
    • A general method for the generation of high-titer, pantropic retroviral vectors: Highly efficient infection of primary hepatocytes
    • Yee, J.K., Miyanohara, A., LaPorte, P., Bouic, K., Burns, J.C. and Friedmann, T. (1994). A general method for the generation of high-titer, pantropic retroviral vectors: highly efficient infection of primary hepatocytes. Proc. Natl. Acad. Sci. USA, 91: 9564-9568.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 9564-9568
    • Yee, J.K.1    Miyanohara, A.2    LaPorte, P.3    Bouic, K.4    Burns, J.C.5    Friedmann, T.6
  • 325
  • 328
    • 0032730633 scopus 로고    scopus 로고
    • Phase I study of an antisense oligonucleotide to protein kinase C-alpha (ISIS 3521/CGP 64128A) in patients with cancer
    • Yuen, A.R., Halsey, J., Fisher, G.A., Holmlund, J.T., Geary, R.S., Kwoh, T.J., Dorr, A. and Sikic, B.I. (1999). Phase I study of an antisense oligonucleotide to protein kinase C-alpha (ISIS 3521/CGP 64128A) in patients with cancer. Clin. Cancer Res., 5: 3357-3363.
    • (1999) Clin. Cancer Res. , vol.5 , pp. 3357-3363
    • Yuen, A.R.1    Halsey, J.2    Fisher, G.A.3    Holmlund, J.T.4    Geary, R.S.5    Kwoh, T.J.6    Dorr, A.7    Sikic, B.I.8
  • 329
    • 10744226368 scopus 로고    scopus 로고
    • Phase I/II clinical trial of a nonreplicative vaccinia virus expressing multiple HLA-A0201-restricted tumor-associated epitopes and costimulatory molecules in metastatic melanoma patients
    • Zajac, P., Oertli, D., Marti, W., Adamina, M., Bolli, M., Guller, U., Noppen, C., Padovan, E., Schultz-Thater, E., Heberer, M. and Spagnoli, G. (2003). Phase I/II clinical trial of a nonreplicative vaccinia virus expressing multiple HLA-A0201-restricted tumor-associated epitopes and costimulatory molecules in metastatic melanoma patients. Hum. Gene Ther., 14: 1497-1510.
    • (2003) Hum. Gene Ther. , vol.14 , pp. 1497-1510
    • Zajac, P.1    Oertli, D.2    Marti, W.3    Adamina, M.4    Bolli, M.5    Guller, U.6    Noppen, C.7    Padovan, E.8    Schultz-Thater, E.9    Heberer, M.10    Spagnoli, G.11
  • 330
    • 0037627875 scopus 로고    scopus 로고
    • Why did p53 gene therapy fail in ovarian cancer?
    • Zeimet, A.G. and Marth, C. (2003). Why did p53 gene therapy fail in ovarian cancer? Lancet Oncol., 4: 415-422.
    • (2003) Lancet Oncol. , vol.4 , pp. 415-422
    • Zeimet, A.G.1    Marth, C.2
  • 332
    • 0031969264 scopus 로고    scopus 로고
    • Angiogenesis and tumor metastasis
    • Zetter, B.R. (1998). Angiogenesis and tumor metastasis. Annu. Rev. Med, 49: 407-424.
    • (1998) Annu. Rev. Med. , vol.49 , pp. 407-424
    • Zetter, B.R.1
  • 333
    • 0028403234 scopus 로고
    • High-efficiency gene transfer and high-level expression of wild-type p53 in human lung cancer cells mediated by recombinant adenovirus
    • Zhang, W.W., Fang, X., Mazur, W., French, B.A., Georges, R.N. and Roth, J.A. (1994). High-efficiency gene transfer and high-level expression of wild-type p53 in human lung cancer cells mediated by recombinant adenovirus. Cancer Gene Ther., 1: 5-13.
    • (1994) Cancer Gene Ther. , vol.1 , pp. 5-13
    • Zhang, W.W.1    Fang, X.2    Mazur, W.3    French, B.A.4    Georges, R.N.5    Roth, J.A.6


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