Adeno-associated virus-mediated delivery of antiangiogenic factors as an antitumor strategy

Cancer Research

Volumn 58, Issue 24, 1998, Pages 5673-5677

  Nguyen, Josephine T ^a   Wu, Ping ^a   Clouse, Melvin E ^a   Hlatky, Lynn ^b,c   Terwilliger, Ernest F ^a  

^a BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c DANA FARBER CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOGENESIS INHIBITOR; ANGIOSTATIN; COMPLEMENTARY RNA; THROMBOCYTE FACTOR 4; VASCULOTROPIN;

ADENO ASSOCIATED VIRUS; ARTICLE; CANCER THERAPY; GENE TARGETING; GENE THERAPY; GENETIC TRANSDUCTION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; VIRUS RECOMBINANT;

ANGIOSTATINS; COLLAGEN; CULTURE MEDIA, CONDITIONED; DEPENDOVIRUS; ENDOSTATINS; ENDOTHELIAL GROWTH FACTORS; GENE THERAPY; GENETIC VECTORS; LYMPHOKINES; PEPTIDE FRAGMENTS; PLASMINOGEN; RECOMBINANT PROTEINS; RNA, ANTISENSE; TRANSFECTION; TUMOR CELLS, CULTURED; VASCULAR ENDOTHELIAL GROWTH FACTOR A; VASCULAR ENDOTHELIAL GROWTH FACTORS;

EID: 0032535405     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (21)

1. Folkman, J. Clinical applications of research on angiogenesis. N. Engl. J. Med., 333: 1757-1763, 1995.
2. Boehm, T., Folkman, J., Browder, T., and O'Reilly, M. S. Anti-angiogenic therapy of experimental cancer does not induce acquired drug resistance. Nature (Lond.), 390: 404-407, 1997.
3. Hlatky, L., Hahnfeldt, P., Tsionou, C., and Coleman, C. N. Vascular endothelial growth factor: environmental controls and effects in angiogenesis. Br. J. Cancer, 74 (Suppl. 27): S151-S156, 1996.
4. Brown, L. F., Detmar, M., Claffey, K., Nagy, J. A., Feng, D., Dvorak, A. M., and Dvorak, H. F. Vascular permeability factor/vascular endothelial growth factor: a multifunctional angiogenic cytokine. Exper. Suppl. (Basel), 79: 233-269, 1997.
5. O'Reilly, M. S., Boehm, T., Shing, Y., Naomi, F., Vasios, G., Lane, W. S,. Flynn, E., Birkhead, J. R., Olsen, B. R., and Folkman, J. Endostatin: an endogenous inhibitor of angiogenesis and tumor growth. Cell, 88: 277-285, 1997.
6. O'Reilly, M. S., Holmgren, L., Shing, Y., Chen, C., Rosenthal, R. A., Moses, M., Lane, W. S., Cao, Y., Sage, E. H., and Folkman, J. Angiostatin: a novel angiogenesis inhibitor that mediates the suppression of metastases by a Lewis lung carcinoma. Cell, 79: 315-328, 1994.
7. Putney, S. D., and Burke, P. A. Improving protein therapeutics with sustained-release formulations. Nat. Biotechnol., 16: 153-157, 1998.
8. Tanaka, T., Manome, Y., Wen, P., Kufe, D. W., and Fine, H. A. Viral vector-mediated transduction of a modified platelet factor 4 cDNA inhibits angiogenesis and tumor growth. Nat. Med., 3: 437-442, 1997.
9. Rolling, F., and Samulski, R. J. AAV as a viral vector for human gene therapy: generation of recombinant virus. Mol. Biotechnol., 3: 9-15, 1995.
10. Muzyczka, N. Use of AAV as a general transduction vector for mammalian cells. Curr. Top. Microbiol. Immunol. 158: 97-131, 1992.
11. Xiao, X., Li, J., and Samulski, R. J. Efficient long-term gene transfer into muscle tissue of immunocompetent mice by adeno-associated virus vector. J. Virol., 70: 8098-8108, 1996.
12. Cao, Y., Ji, R. W., Davidson, D., Schaller, J., Marti, D., Sohndel, S., McCance, S. G., O'Reilly, M. S., Llinas, M., and Folkman, J. Kringle domains of human angiostatin. J. Biol. Chem., 271: 29461-29467, 1996.
13. Du, B., Wu, P., Boldt-Houle, D. M., and Terwilliger, E. F. Efficient transduction of human neurons with an adeno-associated virus vector. Gene Ther., 3: 254-261, 1996.
14. Wigler, M., Pellicer, A., Silverstein, S., Axel, B., Urlaub, G., and Chasin, L. DNA mediated transfer of the adenine phosphoribosyltransferase locus into mammalian cells. Proc. Natl. Acad. Sci. USA, 76: 1373-1376, 1979.
15. Sambrook, J., Fritsch, E. F., and Maniatis, T. Molecular Cloning: a Laboratory Manual, 2nd ed., pp. 1.90-1.104. New York: Cold Spring Harbor Laboratory Press, 1989.
16. Claffey, K. P., Brown, L. F., del Aguila, L. F., Tognazzi, K., Yeo, K-T., Manseau, E. J., and Dvorak, H. F. Expression of VPF/VEGF by melanoma cells increases tumor growth, angiogenesis, and experimental metastasis. Cancer Res., 56: 172-181, 1996.
17. Saleh, M., Stacker, S. A., Wilks, A. F. Inhibition of growth of C6 glioma cells in vivo by expression of antisense vascular endothelial growth factor sequence. Cancer Res., 56: 393-401, 1996.
18. Cheng, S. Y., Huang, H. J., Nagane, M., Ji, X. D., Wang, D., Shin, C. C., Arap, W., Huang, C. M., and Cavenee, W. K. Suppression of glioblastoma angiogenicity and tumorigenicity by inhibition of endogenous expression of vascular endothelial growth factor. Proc. Natl. Acad. Sci. USA, 93: 8502-8507, 1996.
19. Stratmann, A., Machein, M. R., and Plate, K. H. Anti-angiogenic gene therapy of malignant glioma. Acta Neurochirurgica Suppl., 68: 105-110, 1997.
20. Kong, H. L., Hecht, D., Song, W., Kovesdi, I., Hackett, N. R., Yayon. A., and Crystal, R. G. Regional suppression of tumor growth by in vivo transfer of a cDNA encoding a secreted form of the extracellular domain of the flt-1 vascular endothelial growth factor receptor. Hum. Gene Ther., 9: 823-833, 1998.
21. Lin, P., Buxton, J. A., Acheson, A., Radziejewski, C., Maisonpierre, P. C., Yancopoulos, G. D., Channon, K. M., Hale, L. P., Dew hirst, M. W., George. S. E., et al. Antiangiogenic gene therapy targeting the endothelium-specific receptor tyrosine kinase Tie2. Proc. Natl. Acad. Sci. USA, 95: 8829-8834, 1998.