Lack of toxicity of EGFR antisense gene therapy

Journal of Experimental Therapeutics and Oncology

Volumn 2, Issue 3, 2002, Pages 174-186

  Zeng, Qing ^a   Kanter, Peter M ^g   Dhir, Rajiv ^c   Gooding, William E ^d,f   Huang, Leaf ^e   Grandis, Jennifer Rubin ^a,b  

^a Department of Otolaryngology ^*  (United States)

^b Pharmacology   (United States)

^c Labcorp   (United States)

^d Clinical Biostatistics   (United States)

^e UNIVERSITY OF PITTSBURGH   (United States)

^f UNIVERSITY OF PITTSBURGH CANCER INSTITUTE   (United States)

^g ROSWELL PARK CANCER INSTITUTE   (United States)

Author keywords

Antisense; EGFR; Intramuscular injection; Liposome; Toxicity

Indexed keywords

COMPLEMENTARY DNA; EPIDERMAL GROWTH FACTOR RECEPTOR; EPIDERMAL GROWTH FACTOR RECEPTOR ANTIBODY; LIPOSOME;

ACUTE TOXICITY; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE MARROW TOXICITY; CANCER MODEL; CANCER THERAPY; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOSE RESPONSE; DRUG FORMULATION; FEMALE; GENE THERAPY; GENE TRANSFER; HEAD AND NECK CARCINOMA; HUMAN; INFLAMMATION; INFLAMMATORY INFILTRATE; INJECTION SITE; LYMPH NODE HYPERPLASIA; MALE; MOUSE; NONHUMAN; PHASE 1 CLINICAL TRIAL; PRIORITY JOURNAL; SQUAMOUS CELL CARCINOMA; XENOGRAFT; ANIMAL; BONE MARROW; DRUG ANTAGONISM; DRUG EFFECT; GENETICS; HYPERPLASIA; INSTITUTE FOR CANCER RESEARCH MOUSE; INTRAMUSCULAR DRUG ADMINISTRATION; KIDNEY; LIVER; LYMPH NODE; METHODOLOGY; PATHOLOGY; PHYSIOLOGY;

ANIMAL; BONE MARROW; DNA, ANTISENSE; FEMALE; GENE THERAPY; HYPERPLASIA; INJECTIONS, INTRAMUSCULAR; KIDNEY; LIPOSOMES; LIVER; LYMPH NODES; MALE; MICE; MICE, INBRED ICR; RECEPTOR, EPIDERMAL GROWTH FACTOR; SUPPORT, U.S. GOV'T, P.H.S.; ANIMALS;

EID: 0035998727     PISSN: 13594117     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1359-4117.2002.01033.x     Document Type: Article

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