Phase I trial of recombinant adenovirus gene transfer in lung cancer: Longitudinal study of the immune responses to transgene and viral products

Journal of Clinical Investigation

Volumn 100, Issue 9, 1997, Pages 2218-2226

  Gahéry Ségard, Hanne ^a   Molinier Frenkel, Valérie ^b   Le Boulaire, Christophe ^b   Saulnier, Patrick ^b   Opolon, Paule ^b   Lengagne, Renée ^a   Gautier, Eric ^b   Le Cesne, Axel ^b   Zitvogel, Laurence ^b   Venet, Alain ^a   Schatz, Christian ^c   Courtney, Michael ^c   Le Chevalier, Thierry ^b   Tursz, Thomas ^b   Guillet, Jean Gérard ^a   Farace, Françoise ^b  

^a Hôpital Cochin ^*  (France)

^b INSTITUT GUSTAVE ROUSSY   (France)

^c TRANSGENE S A   (France)

Author keywords

Cancer; Gene therapy; Humans; Immune responses; Recombinant adenovirus

Indexed keywords

BETA GALACTOSIDASE; NEUTRALIZING ANTIBODY; VIRUS DNA;

ADENOVIRUS; ARTICLE; CASE REPORT; CELLULAR IMMUNITY; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; GENE THERAPY; GENE TRANSFER; HUMAN; HUMAN CELL; HUMAN TISSUE; HUMORAL IMMUNITY; IMMUNE RESPONSE; LUNG CANCER; PHASE 1 CLINICAL TRIAL; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; VIRUS RECOMBINANT;

EID: 0141637540     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI119759     Document Type: Article

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