Potent and nontoxic antisense oligonudeotides containing locked nucleic acids

Proceedings of the National Academy of Sciences of the United States of America

Volumn 97, Issue 10, 2000, Pages 5633-5638

  Wahlestedt, Claes ^a   Salmi, Peter ^a   Good, Liam ^a   Kela, Johanna ^a   Johnsson, Thomas ^a   Hökfelt, Tomas ^a   Broberger, Christian ^a   Porreca, Frank ^b   Lai, Josephine ^b   Ren, Kunkun ^b   Ossipov, Michael ^b   Koshkin, Alexei ^c   Jakobsen, Nana ^c   Skouv, Jan ^c,d   Oerum, Henrik ^c   Jacobsen, Mogens Havsteen ^c   Wengel, Jesper ^e  

^a KAROLINSKA INSTITUTE   (Sweden)

^b UNIVERSITY OF ARIZONA COLLEGE OF MEDICINE   (United States)

^c Exiqon AS   (Denmark)

^d DANISH CANCER SOCIETY RESEARCH CENTER   (Denmark)

^e UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE; G PROTEIN COUPLED RECEPTOR; NUCLEIC ACID; RIBONUCLEASE;

ANIMAL CELL; ARTICLE; BASE MISPAIRING; BRAIN; CAUDATE NUCLEUS; CONTROLLED STUDY; DNA DEGRADATION; GENE ACTIVATION; NONHUMAN; NUCLEIC ACID PROBE; PRIORITY JOURNAL; PUTAMEN; RAT;

ANIMALS; BASE SEQUENCE; BIOLOGICAL TRANSPORT; BREAST NEOPLASMS; CAUDATE NUCLEUS; CEREBRAL VENTRICLES; DRUG DESIGN; ENZYME ACTIVATION; FEMALE; HUMANS; OLIGODEOXYRIBONUCLEOTIDES, ANTISENSE; PUTAMEN; RATS; RECEPTORS, OPIOID, DELTA; RIBONUCLEASE H, CALF THYMUS; STEREOTAXIC TECHNIQUES; THIONUCLEOTIDES; TUMOR CELLS, CULTURED;

ANIMALIA; ESCHERICHIA COLI;

EID: 0034625010     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.97.10.5633     Document Type: Article

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