Localization of mouse mitochondrial SIRT proteins: Shift of SIRT3 to nucleus by co-expression with SIRT5

Biochemical and Biophysical Research Communications

Volumn 366, Issue 1, 2008, Pages 174-179

  Nakamura, Yasuhiko ^a   Ogura, Masahito ^a   Tanaka, Daisuke ^a   Inagaki, Nobuya ^a  

^a KYOTO UNIVERSITY   (Japan)

Author keywords

Intramitochondrial localization; Localization shift; SIRT3; SIRT4; SIRT5

Indexed keywords

MITOCHONDRIAL PROTEIN; REGULATOR PROTEIN; SILENT INFORMATION REGULATOR 3; SILENT INFORMATION REGULATOR 4; SILENT INFORMATION REGULATOR 5; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL NUCLEUS; CELLULAR DISTRIBUTION; MITOCHONDRION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION;

ANIMALS; CELL NUCLEUS; CERCOPITHECUS AETHIOPS; COS CELLS; GENE EXPRESSION REGULATION; MICE; MITOCHONDRIAL PROTEINS; PROTEIN TRANSPORT; SIRTUINS;

MAMMALIA;

EID: 37549026223     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2007.11.122     Document Type: Article

References (18)

1. Tanny J.C., Dowd G.J., Huang J., Hilz H., and Moazed D. An enzymatic activity in the yeast Sir2 protein that is essential for gene silencing. Cell 99 (1999) 735-745
2. Imai S., Armstrong C.M., Kaeberlein M., and Guarente L. Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase. Nature 403 (2000) 795-800
3. Gotta M., Strahl-Bolsinger S., Renauld H., Laroche T., Kennedy B.K., Grunstein M., and Gasser S.M. Localization of Sir2p: the nucleolus as a compartment for silent information regulators. EMBO J. 16 (1997) 3243-3255
4. Muller I., Zimmermann M., Becker D., and Flomer M. Calendar life span versus budding life span of Saccharomyces cerevisiae. Mech. Aging Dev. 12 (1980) 47-52
5. Lin S.J., Kaeberlein M., Andalis A.A., Sturtz L.A., Defossez P.A., Culotta V.C., Fink G.R., and Guarente L. Calorie restriction extends Saccharomyces cerevisiae lifespan by increasing respiration. Nature 418 (2002) 344-348
6. Lin S.J., Defossez P.A., and Guarente L. Requirement of NAD and SIR2 for life-span extension by calorie restriction in Saccharomyces cerevisiae. Science 289 (2000) 2126-2128
7. Michishita E., Park J.Y., Burneskis J.M., Barrett J.C., and Horikawa I. Evolutionarily conserved and nonconserved cellular localizations and functions of human SIRT proteins. Mol. Biol. Cell 16 (2005) 4623-4635
8. Onyango P., Celic I., McCaffery J.M., Boeke J.D., and Feinberg A.P. SIRT3, a human SIR2 homologue, is an NAD-dependent deacetylase localized to mitochondria. Proc. Natl. Acad. Sci. USA 99 (2002) 13653-13658
9. Haigis M.C., Mostoslavsky R., Haigis K.M., Fahie K., Christodoulou D.C., Murphy A.J., Valenzuela D.M., Yancopoulos G.D., Karow M., Blander G., Wolberger C., Prolla T.A., Weindruch R., Alt F.W., and Guarente L. SIRT4 inhibits glutamate dehydrogenase and opposes the effects of calorie restriction in pancreatic β cells. Cell 126 (2006) 941-954
10. Schwer B., Bunkenborg J., Verdin R.O., Andersen J.S., and Verdin E. Reversible lysine acetylation controls the activity of the mitochondrial enzyme acetyl-CoA synthetase 2. Proc. Natl. Acad. Sci. USA 103 (2006) 10224-10229
11. Hallows W.C., Lee S., and Denu J.M. Sirtuins deacetylate and activate mammalian acetyl-CoA synthetases. Proc. Natl. Acad. Sci. USA 103 (2006) 10230-10235
12. +-dependent tubulin deacetylase. Mol. Cell 11 (2003) 437-444
13. Shi T., Wang F., Stieren E., and Tong Q. SIRT3, a mitochondrial sirtuin deacetylase, regulates mitochondrial function and thermogenesis in brown adipocytes. J. Biol. Chem. 280 (2005) 13560-13567
14. Schwer B., North B.J., Frye R.A., Ott M., and Verdin E. The human silent information regulator (Sir)2 homologue hSIRT3 is a mitochondrial nicotinamide adenine dinucleotide-dependent deacetylase. J. Cell Biol. 158 (2002) 647-657
15. Ho S.N., Hunt H.D., Horton R.M., Pullen J.K., and Pease L.R. Site-directed mutagenesis by overlap extension using the polymerase chain reaction. Gene 77 (1989) 51-59
16. Matsumura Y., Ban N., Ueda K., and Inagaki N. Characterization and classification of ATP-binding cassette transporter ABCA3 mutants in fatal surfactant deficiency. J. Biol. Chem. 281 (2006) 34503-34514
17. Nakamura Y., Suzuki H., Sakaguchi M., and Mihara K. Targeting and assembly of rat mitochondrial translocase of outer membrane 22 (TOM22) into the TOM complex. J. Biol. Chem. 279 (2004) 21223-21232
18. Kasashima K., Ohta E., Kagawa Y., and Endo H. Mitochondrial functions and estrogen receptor-dependent nuclear translocation of pleiotropic human prohibitin 2. J. Biol. Chem. 281 (2006) 36401-36410