-
2
-
-
33646117239
-
Spatial organization of the mammalian genome surveillance machinery in response to DNA strand breaks
-
Bekker-Jensen S., Lukas C., Kitagawa R., Melander F., Kastan M.B., Bartek J., and Lukas J. Spatial organization of the mammalian genome surveillance machinery in response to DNA strand breaks. J. Cell Biol. 173 (2006) 195-206
-
(2006)
J. Cell Biol.
, vol.173
, pp. 195-206
-
-
Bekker-Jensen, S.1
Lukas, C.2
Kitagawa, R.3
Melander, F.4
Kastan, M.B.5
Bartek, J.6
Lukas, J.7
-
3
-
-
33845604556
-
DNA double-strand break repair: all's well that ends well
-
Wyman C., and Kanaar R. DNA double-strand break repair: all's well that ends well. Annu. Rev. Genet. 40 (2006) 363-383
-
(2006)
Annu. Rev. Genet.
, vol.40
, pp. 363-383
-
-
Wyman, C.1
Kanaar, R.2
-
4
-
-
7944231563
-
Non-homologous end-joining factors of Saccharomyces cerevisiae
-
Dudasova Z., Dudas A., and Chovanec M. Non-homologous end-joining factors of Saccharomyces cerevisiae. FEMS Microbiol. Rev. 28 (2004) 581-601
-
(2004)
FEMS Microbiol. Rev.
, vol.28
, pp. 581-601
-
-
Dudasova, Z.1
Dudas, A.2
Chovanec, M.3
-
5
-
-
0032530658
-
Homologous recombination and non-homologous end-joining pathways of DNA double-strand break repair have overlapping roles in the maintenance of chromosomal integrity in vertebrate cells
-
Takata M., Sasaki M.S., Sonoda E., Morrison C., Hashimoto M., Utsumi H., Yamaguchi-Iwai Y., Shinohara A., and Takeda S. Homologous recombination and non-homologous end-joining pathways of DNA double-strand break repair have overlapping roles in the maintenance of chromosomal integrity in vertebrate cells. EMBO J. 17 (1998) 5497-5508
-
(1998)
EMBO J.
, vol.17
, pp. 5497-5508
-
-
Takata, M.1
Sasaki, M.S.2
Sonoda, E.3
Morrison, C.4
Hashimoto, M.5
Utsumi, H.6
Yamaguchi-Iwai, Y.7
Shinohara, A.8
Takeda, S.9
-
6
-
-
0029976325
-
Cell cycle and genetic requirements of two pathways of nonhomologous end-joining repair of double-strand breaks in Saccharomyces cerevisiae
-
Moore J.K., and Haber J.E. Cell cycle and genetic requirements of two pathways of nonhomologous end-joining repair of double-strand breaks in Saccharomyces cerevisiae. Mol. Cell. Biol. 16 (1996) 2164-2173
-
(1996)
Mol. Cell. Biol.
, vol.16
, pp. 2164-2173
-
-
Moore, J.K.1
Haber, J.E.2
-
7
-
-
52049098230
-
Comparison of nonhomologous end joining and homologous recombination in human cells
-
Mao Z., Bozzella M., Seluanov A., and Gorbunova V. Comparison of nonhomologous end joining and homologous recombination in human cells. DNA Repair (Amst.) 7 (2008) 1765-1771
-
(2008)
DNA Repair (Amst.)
, vol.7
, pp. 1765-1771
-
-
Mao, Z.1
Bozzella, M.2
Seluanov, A.3
Gorbunova, V.4
-
8
-
-
0033565609
-
Role of yeast SIR genes and mating type in directing DNA double-strand breaks to homologous and non-homologous repair paths
-
Lee S.E., Paques F., Sylvan J., and Haber J.E. Role of yeast SIR genes and mating type in directing DNA double-strand breaks to homologous and non-homologous repair paths. Curr. Biol. 9 (1999) 767-770
-
(1999)
Curr. Biol.
, vol.9
, pp. 767-770
-
-
Lee, S.E.1
Paques, F.2
Sylvan, J.3
Haber, J.E.4
-
9
-
-
19344370467
-
Mechanism of DNA double-strand break repair by non-homologous end joining
-
Hefferin M.L., and Tomkinson A.E. Mechanism of DNA double-strand break repair by non-homologous end joining. DNA Repair (Amst.) 4 (2005) 639-648
-
(2005)
DNA Repair (Amst.)
, vol.4
, pp. 639-648
-
-
Hefferin, M.L.1
Tomkinson, A.E.2
-
10
-
-
0037090535
-
Nuclear dynamics of RAD52 group homologous recombination proteins in response to DNA damage
-
Essers J., Houtsmuller A.B., van Veelen L., Paulusma C., Nigg A.L., Pastink A., Vermeulen W., Hoeijmakers J.H., and Kanaar R. Nuclear dynamics of RAD52 group homologous recombination proteins in response to DNA damage. EMBO J. 21 (2002) 2030-2037
-
(2002)
EMBO J.
, vol.21
, pp. 2030-2037
-
-
Essers, J.1
Houtsmuller, A.B.2
van Veelen, L.3
Paulusma, C.4
Nigg, A.L.5
Pastink, A.6
Vermeulen, W.7
Hoeijmakers, J.H.8
Kanaar, R.9
-
11
-
-
45149104841
-
Recruitment and dissociation of nonhomologous end joining proteins at a DNA double-strand break in Saccharomyces cerevisiae
-
Wu D., Topper L.M., and Wilson T.E. Recruitment and dissociation of nonhomologous end joining proteins at a DNA double-strand break in Saccharomyces cerevisiae. Genetics 178 (2008) 1237-1249
-
(2008)
Genetics
, vol.178
, pp. 1237-1249
-
-
Wu, D.1
Topper, L.M.2
Wilson, T.E.3
-
12
-
-
0033612287
-
Relocalization of telomeric Ku and SIR proteins in response to DNA strand breaks in yeast
-
Martin S.G., Laroche T., Suka N., Grunstein M., and Gasser S.M. Relocalization of telomeric Ku and SIR proteins in response to DNA strand breaks in yeast. Cell 97 (1999) 621-633
-
(1999)
Cell
, vol.97
, pp. 621-633
-
-
Martin, S.G.1
Laroche, T.2
Suka, N.3
Grunstein, M.4
Gasser, S.M.5
-
13
-
-
4544281398
-
Choreography of the DNA damage response; spatiotemporal relationships among checkpoint and repair proteins
-
Lisby M., Barlow J.H., Burgess R.C., and Rothstein R. Choreography of the DNA damage response; spatiotemporal relationships among checkpoint and repair proteins. Cell 118 (2004) 699-713
-
(2004)
Cell
, vol.118
, pp. 699-713
-
-
Lisby, M.1
Barlow, J.H.2
Burgess, R.C.3
Rothstein, R.4
-
14
-
-
0029954821
-
Mutations in two Ku homologs define a DNA end-joining repair pathway in Saccharomyces cerevisiae
-
Milne G.T., Jin S., Shannon K.B., and Weaver D.T. Mutations in two Ku homologs define a DNA end-joining repair pathway in Saccharomyces cerevisiae. Mol. Cell. Biol. 16 (1996) 4189-4198
-
(1996)
Mol. Cell. Biol.
, vol.16
, pp. 4189-4198
-
-
Milne, G.T.1
Jin, S.2
Shannon, K.B.3
Weaver, D.T.4
-
15
-
-
0035906860
-
Structural biochemistry and interaction architecture of the DNA double-strand break repair Mre11 nuclease and Rad50-ATPase
-
Hopfner K.P., Karcher A., Craig L., Woo T.T., Carney J.P., and Tainer J.A. Structural biochemistry and interaction architecture of the DNA double-strand break repair Mre11 nuclease and Rad50-ATPase. Cell 105 (2001) 473-485
-
(2001)
Cell
, vol.105
, pp. 473-485
-
-
Hopfner, K.P.1
Karcher, A.2
Craig, L.3
Woo, T.T.4
Carney, J.P.5
Tainer, J.A.6
-
16
-
-
0035930342
-
Promotion of Dnl4-catalyzed DNA end-joining by the Rad50/Mre11/Xrs2 and Hdf1/Hdf2 complexes
-
Chen L., Trujillo K., Ramos W., Sung P., and Tomkinson A.E. Promotion of Dnl4-catalyzed DNA end-joining by the Rad50/Mre11/Xrs2 and Hdf1/Hdf2 complexes. Mol. Cell 8 (2001) 1105-1115
-
(2001)
Mol. Cell
, vol.8
, pp. 1105-1115
-
-
Chen, L.1
Trujillo, K.2
Ramos, W.3
Sung, P.4
Tomkinson, A.E.5
-
17
-
-
0032493889
-
Saccharomyces Ku70, Mre11/Rad50 and RPA proteins regulate adaptation to G2/M arrest after DNA damage
-
Lee S.E., Moore J.K., Holmes A., Umezu K., Kolodner R.D., and Haber J.E. Saccharomyces Ku70, Mre11/Rad50 and RPA proteins regulate adaptation to G2/M arrest after DNA damage. Cell 94 (1998) 399-409
-
(1998)
Cell
, vol.94
, pp. 399-409
-
-
Lee, S.E.1
Moore, J.K.2
Holmes, A.3
Umezu, K.4
Kolodner, R.D.5
Haber, J.E.6
-
18
-
-
53649104599
-
Sae2, Exo1 and Sgs1 collaborate in DNA double-strand break processing
-
Mimitou E.P., and Symington L.S. Sae2, Exo1 and Sgs1 collaborate in DNA double-strand break processing. Nature 455 (2008) 770-774
-
(2008)
Nature
, vol.455
, pp. 770-774
-
-
Mimitou, E.P.1
Symington, L.S.2
-
19
-
-
51549095956
-
Sgs1 helicase and two nucleases Dna2 and Exo1 resect DNA double-strand break ends
-
Zhu Z., Chung W.H., Shim E.Y., Lee S.E., and Ira G. Sgs1 helicase and two nucleases Dna2 and Exo1 resect DNA double-strand break ends. Cell 134 (2008) 981-994
-
(2008)
Cell
, vol.134
, pp. 981-994
-
-
Zhu, Z.1
Chung, W.H.2
Shim, E.Y.3
Lee, S.E.4
Ira, G.5
-
20
-
-
0035929667
-
DNA structure-specific nuclease activities in the Saccharomyces cerevisiae Rad50*Mre11 complex
-
Trujillo K.M., and Sung P. DNA structure-specific nuclease activities in the Saccharomyces cerevisiae Rad50*Mre11 complex. J. Biol. Chem. 276 (2001) 35458-35464
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 35458-35464
-
-
Trujillo, K.M.1
Sung, P.2
-
21
-
-
0028789631
-
Covalent protein-DNA complexes at the 5′ strand termini of meiosis-specific double-strand breaks in yeast
-
Keeney S., and Kleckner N. Covalent protein-DNA complexes at the 5′ strand termini of meiosis-specific double-strand breaks in yeast. Proc. Natl. Acad. Sci. U.S.A. 92 (1995) 11274-11278
-
(1995)
Proc. Natl. Acad. Sci. U.S.A.
, vol.92
, pp. 11274-11278
-
-
Keeney, S.1
Kleckner, N.2
-
22
-
-
0035692142
-
Overlapping functions of the Saccharomyces cerevisiae Mre11, Exo1 and Rad27 nucleases in DNA metabolism
-
Moreau S., Morgan E.A., and Symington L.S. Overlapping functions of the Saccharomyces cerevisiae Mre11, Exo1 and Rad27 nucleases in DNA metabolism. Genetics 159 (2001) 1423-1433
-
(2001)
Genetics
, vol.159
, pp. 1423-1433
-
-
Moreau, S.1
Morgan, E.A.2
Symington, L.S.3
-
23
-
-
0037169325
-
The Mre11 complex is required for repair of hairpin-capped double-strand breaks and prevention of chromosome rearrangements
-
Lobachev K.S., Gordenin D.A., and Resnick M.A. The Mre11 complex is required for repair of hairpin-capped double-strand breaks and prevention of chromosome rearrangements. Cell 108 (2002) 183-193
-
(2002)
Cell
, vol.108
, pp. 183-193
-
-
Lobachev, K.S.1
Gordenin, D.A.2
Resnick, M.A.3
-
24
-
-
34948872046
-
Ctp1 is a cell-cycle-regulated protein that functions with Mre11 complex to control double-strand break repair by homologous recombination
-
Limbo O., Chahwan C., Yamada Y., de Bruin R.A., Wittenberg C., and Russell P. Ctp1 is a cell-cycle-regulated protein that functions with Mre11 complex to control double-strand break repair by homologous recombination. Mol. Cell 28 (2007) 134-146
-
(2007)
Mol. Cell
, vol.28
, pp. 134-146
-
-
Limbo, O.1
Chahwan, C.2
Yamada, Y.3
de Bruin, R.A.4
Wittenberg, C.5
Russell, P.6
-
25
-
-
33644691699
-
The Saccharomyces cerevisiae Sae2 protein promotes resection and bridging of double strand break ends
-
Clerici M., Mantiero D., Lucchini G., and Longhese M.P. The Saccharomyces cerevisiae Sae2 protein promotes resection and bridging of double strand break ends. J. Biol. Chem. 280 (2005) 38631-38638
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 38631-38638
-
-
Clerici, M.1
Mantiero, D.2
Lucchini, G.3
Longhese, M.P.4
-
26
-
-
10344240414
-
Chromosome fragmentation after induction of a double-strand break is an active process prevented by the RMX repair complex
-
Lobachev K., Vitriol E., Stemple J., Resnick M.A., and Bloom K. Chromosome fragmentation after induction of a double-strand break is an active process prevented by the RMX repair complex. Curr. Biol. 14 (2004) 2107-2112
-
(2004)
Curr. Biol.
, vol.14
, pp. 2107-2112
-
-
Lobachev, K.1
Vitriol, E.2
Stemple, J.3
Resnick, M.A.4
Bloom, K.5
-
28
-
-
0041660970
-
ATM-related Tel1 associates with double-strand breaks through an Xrs2-dependent mechanism
-
Nakada D., Matsumoto K., and Sugimoto K. ATM-related Tel1 associates with double-strand breaks through an Xrs2-dependent mechanism. Genes Dev. 17 (2003) 1957-1962
-
(2003)
Genes Dev.
, vol.17
, pp. 1957-1962
-
-
Nakada, D.1
Matsumoto, K.2
Sugimoto, K.3
-
29
-
-
0032489520
-
DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139
-
Rogakou E.P., Pilch D.R., Orr A.H., Ivanova V.S., and Bonner W.M. DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139. J. Biol. Chem. 273 (1998) 5858-5868
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 5858-5868
-
-
Rogakou, E.P.1
Pilch, D.R.2
Orr, A.H.3
Ivanova, V.S.4
Bonner, W.M.5
-
30
-
-
0043066728
-
Yeast histone 2A serine 129 is essential for the efficient repair of checkpoint-blind DNA damage
-
Redon C., Pilch D.R., Rogakou E.P., Orr A.H., Lowndes N.F., and Bonner W.M. Yeast histone 2A serine 129 is essential for the efficient repair of checkpoint-blind DNA damage. EMBO Rep. 4 (2003) 678-684
-
(2003)
EMBO Rep.
, vol.4
, pp. 678-684
-
-
Redon, C.1
Pilch, D.R.2
Rogakou, E.P.3
Orr, A.H.4
Lowndes, N.F.5
Bonner, W.M.6
-
31
-
-
0032861343
-
Megabase chromatin domains involved in DNA double-strand breaks in vivo
-
Rogakou E.P., Boon C., Redon C., and Bonner W.M. Megabase chromatin domains involved in DNA double-strand breaks in vivo. J. Cell Biol. 146 (1999) 905-916
-
(1999)
J. Cell Biol.
, vol.146
, pp. 905-916
-
-
Rogakou, E.P.1
Boon, C.2
Redon, C.3
Bonner, W.M.4
-
32
-
-
33646777111
-
Histone H2A phosphorylation and H3 methylation are required for a novel Rad9 DSB repair function following checkpoint activation
-
Toh G.W., O'Shaughnessy M., Jimeno A.S., Dobbie I.M., Grenon M., Maffini S., O'Rorke A., and Lowndes N.F. Histone H2A phosphorylation and H3 methylation are required for a novel Rad9 DSB repair function following checkpoint activation. DNA Repair (Amst.) 5 (2006) 693-703
-
(2006)
DNA Repair (Amst.)
, vol.5
, pp. 693-703
-
-
Toh, G.W.1
O'Shaughnessy, M.2
Jimeno, A.S.3
Dobbie, I.M.4
Grenon, M.5
Maffini, S.6
O'Rorke, A.7
Lowndes, N.F.8
-
33
-
-
53349162987
-
CDK targets Sae2 to control DNA-end resection and homologous recombination
-
Huertas P., Cortes-Ledesma F., Sartori A.A., Aguilera A., and Jackson S.P. CDK targets Sae2 to control DNA-end resection and homologous recombination. Nature 455 (2008) 689-692
-
(2008)
Nature
, vol.455
, pp. 689-692
-
-
Huertas, P.1
Cortes-Ledesma, F.2
Sartori, A.A.3
Aguilera, A.4
Jackson, S.P.5
-
34
-
-
22144434446
-
Multiple endonucleases function to repair covalent topoisomerase I complexes in Saccharomyces cerevisiae
-
Deng C., Brown J.A., You D., and Brown J.M. Multiple endonucleases function to repair covalent topoisomerase I complexes in Saccharomyces cerevisiae. Genetics 170 (2005) 591-600
-
(2005)
Genetics
, vol.170
, pp. 591-600
-
-
Deng, C.1
Brown, J.A.2
You, D.3
Brown, J.M.4
-
35
-
-
0030759699
-
A general method for identifying recessive diploid-specific mutations in Saccharomyces cerevisiae, its application to the isolation of mutants blocked at intermediate stages of meiotic prophase and characterization of a new gene SAE2
-
McKee A.H., and Kleckner N. A general method for identifying recessive diploid-specific mutations in Saccharomyces cerevisiae, its application to the isolation of mutants blocked at intermediate stages of meiotic prophase and characterization of a new gene SAE2. Genetics 146 (1997) 797-816
-
(1997)
Genetics
, vol.146
, pp. 797-816
-
-
McKee, A.H.1
Kleckner, N.2
-
36
-
-
0030811331
-
Isolation of COM1, a new gene required to complete meiotic double-strand break-induced recombination in Saccharomyces cerevisiae
-
Prinz S., Amon A., and Klein F. Isolation of COM1, a new gene required to complete meiotic double-strand break-induced recombination in Saccharomyces cerevisiae. Genetics 146 (1997) 781-795
-
(1997)
Genetics
, vol.146
, pp. 781-795
-
-
Prinz, S.1
Amon, A.2
Klein, F.3
-
37
-
-
39549114009
-
Differential regulation of the cellular response to DNA double-strand breaks in G1
-
Barlow J.H., Lisby M., and Rothstein R. Differential regulation of the cellular response to DNA double-strand breaks in G1. Mol. Cell 30 (2008) 73-85
-
(2008)
Mol. Cell
, vol.30
, pp. 73-85
-
-
Barlow, J.H.1
Lisby, M.2
Rothstein, R.3
-
38
-
-
7244220162
-
DNA end resection, homologous recombination and DNA damage checkpoint activation require CDK1
-
Ira G., Pellicioli A., Balijja A., Wang X., Fiorani S., Carotenuto W., Liberi G., Bressan D., Wan L., Hollingsworth N.M., et al. DNA end resection, homologous recombination and DNA damage checkpoint activation require CDK1. Nature 431 (2004) 1011-1017
-
(2004)
Nature
, vol.431
, pp. 1011-1017
-
-
Ira, G.1
Pellicioli, A.2
Balijja, A.3
Wang, X.4
Fiorani, S.5
Carotenuto, W.6
Liberi, G.7
Bressan, D.8
Wan, L.9
Hollingsworth, N.M.10
-
39
-
-
42949130159
-
Colocalization of sensors is sufficient to activate the DNA damage checkpoint in the absence of damage
-
Bonilla C.Y., Melo J.A., and Toczyski D.P. Colocalization of sensors is sufficient to activate the DNA damage checkpoint in the absence of damage. Mol. Cell 30 (2008) 267-276
-
(2008)
Mol. Cell
, vol.30
, pp. 267-276
-
-
Bonilla, C.Y.1
Melo, J.A.2
Toczyski, D.P.3
-
40
-
-
45849117573
-
Activation of the cellular DNA damage response in the absence of DNA lesions
-
Soutoglou E., and Misteli T. Activation of the cellular DNA damage response in the absence of DNA lesions. Science 320 (2008) 1507-1510
-
(2008)
Science
, vol.320
, pp. 1507-1510
-
-
Soutoglou, E.1
Misteli, T.2
-
41
-
-
0029119967
-
Complex formation in yeast double-strand break repair: participation of Rad51, Rad52, Rad55, and Rad57 proteins
-
Hays S.L., Firmenich A.A., and Berg P. Complex formation in yeast double-strand break repair: participation of Rad51, Rad52, Rad55, and Rad57 proteins. Proc. Natl. Acad. Sci. U.S.A. 92 (1995) 6925-6929
-
(1995)
Proc. Natl. Acad. Sci. U.S.A.
, vol.92
, pp. 6925-6929
-
-
Hays, S.L.1
Firmenich, A.A.2
Berg, P.3
-
42
-
-
0027227980
-
Dominant negative alleles of RAD52 reveal a DNA repair/recombination complex including Rad51 and Rad52
-
Milne G.T., and Weaver D.T. Dominant negative alleles of RAD52 reveal a DNA repair/recombination complex including Rad51 and Rad52. Genes Dev. 7 (1993) 1755-1765
-
(1993)
Genes Dev.
, vol.7
, pp. 1755-1765
-
-
Milne, G.T.1
Weaver, D.T.2
-
43
-
-
2542422284
-
The Rad52-Rad59 complex interacts with Rad51 and replication protein A
-
Davis A.P., and Symington L.S. The Rad52-Rad59 complex interacts with Rad51 and replication protein A. DNA Repair (Amst.) 2 (2003) 1127-1134
-
(2003)
DNA Repair (Amst.)
, vol.2
, pp. 1127-1134
-
-
Davis, A.P.1
Symington, L.S.2
-
44
-
-
44849138547
-
ATP-dependent chromatin remodeling by the Saccharomyces cerevisiae homologous recombination factor Rdh54
-
Kwon Y., Seong C., Chi P., Greene E.C., Klein H., and Sung P. ATP-dependent chromatin remodeling by the Saccharomyces cerevisiae homologous recombination factor Rdh54. J. Biol. Chem. 283 (2008) 10445-10452
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 10445-10452
-
-
Kwon, Y.1
Seong, C.2
Chi, P.3
Greene, E.C.4
Klein, H.5
Sung, P.6
-
45
-
-
0030786807
-
Characterization of the roles of the Saccharomyces cerevisiae RAD54 gene and a homologue of RAD54, RDH54/TID1, in mitosis and meiosis
-
Shinohara M., Shita-Yamaguchi E., Buerstedde J.M., Shinagawa H., Ogawa H., and Shinohara A. Characterization of the roles of the Saccharomyces cerevisiae RAD54 gene and a homologue of RAD54, RDH54/TID1, in mitosis and meiosis. Genetics 147 (1997) 1545-1556
-
(1997)
Genetics
, vol.147
, pp. 1545-1556
-
-
Shinohara, M.1
Shita-Yamaguchi, E.2
Buerstedde, J.M.3
Shinagawa, H.4
Ogawa, H.5
Shinohara, A.6
-
46
-
-
0030995362
-
Yeast Rad55 and Rad57 proteins form a heterodimer that functions with replication protein A to promote DNA strand exchange by Rad51 recombinase
-
Sung P. Yeast Rad55 and Rad57 proteins form a heterodimer that functions with replication protein A to promote DNA strand exchange by Rad51 recombinase. Genes Dev. 11 (1997) 1111-1121
-
(1997)
Genes Dev.
, vol.11
, pp. 1111-1121
-
-
Sung, P.1
-
47
-
-
0035930329
-
Human Rad50/Mre11 is a flexible complex that can tether DNA ends
-
de Jager M., van Noort J., van Gent D.C., Dekker C., Kanaar R., and Wyman C. Human Rad50/Mre11 is a flexible complex that can tether DNA ends. Mol. Cell 8 (2001) 1129-1135
-
(2001)
Mol. Cell
, vol.8
, pp. 1129-1135
-
-
de Jager, M.1
van Noort, J.2
van Gent, D.C.3
Dekker, C.4
Kanaar, R.5
Wyman, C.6
-
48
-
-
0037109113
-
DNA end-binding specificity of human Rad50/Mre11 is influenced by ATP
-
de Jager M., Wyman C., van Gent D.C., and Kanaar R. DNA end-binding specificity of human Rad50/Mre11 is influenced by ATP. Nucleic Acids Res. 30 (2002) 4425-4431
-
(2002)
Nucleic Acids Res.
, vol.30
, pp. 4425-4431
-
-
de Jager, M.1
Wyman, C.2
van Gent, D.C.3
Kanaar, R.4
-
49
-
-
0022827675
-
Mechanism of interaction between Ku protein and DNA
-
Mimori T., and Hardin J.A. Mechanism of interaction between Ku protein and DNA. J. Biol. Chem. 261 (1986) 10375-10379
-
(1986)
J. Biol. Chem.
, vol.261
, pp. 10375-10379
-
-
Mimori, T.1
Hardin, J.A.2
-
50
-
-
23744447715
-
Independent and sequential recruitment of NHEJ and HR factors to DNA damage sites in mammalian cells
-
Kim J.S., Krasieva T.B., Kurumizaka H., Chen D.J., Taylor A.M., and Yokomori K. Independent and sequential recruitment of NHEJ and HR factors to DNA damage sites in mammalian cells. J. Cell Biol. 170 (2005) 341-347
-
(2005)
J. Cell Biol.
, vol.170
, pp. 341-347
-
-
Kim, J.S.1
Krasieva, T.B.2
Kurumizaka, H.3
Chen, D.J.4
Taylor, A.M.5
Yokomori, K.6
-
51
-
-
33646714595
-
Three-dimensional structure of the human DNA-PKcs/Ku70/Ku80 complex assembled on DNA and its implications for DNA DSB repair
-
Spagnolo L., Rivera-Calzada A., Pearl L.H., and Llorca O. Three-dimensional structure of the human DNA-PKcs/Ku70/Ku80 complex assembled on DNA and its implications for DNA DSB repair. Mol. Cell 22 (2006) 511-519
-
(2006)
Mol. Cell
, vol.22
, pp. 511-519
-
-
Spagnolo, L.1
Rivera-Calzada, A.2
Pearl, L.H.3
Llorca, O.4
-
52
-
-
0037124373
-
Synapsis of DNA ends by DNA-dependent protein kinase
-
DeFazio L.G., Stansel R.M., Griffith J.D., and Chu G. Synapsis of DNA ends by DNA-dependent protein kinase. EMBO J. 21 (2002) 3192-3200
-
(2002)
EMBO J.
, vol.21
, pp. 3192-3200
-
-
DeFazio, L.G.1
Stansel, R.M.2
Griffith, J.D.3
Chu, G.4
-
53
-
-
33751583362
-
Conditional deletion of Nbs1 in murine cells reveals its role in branching repair pathways of DNA double-strand breaks
-
Yang Y.G., Saidi A., Frappart P.O., Min W., Barrucand C., Dumon-Jones V., Michelon J., Herceg Z., and Wang Z.Q. Conditional deletion of Nbs1 in murine cells reveals its role in branching repair pathways of DNA double-strand breaks. EMBO J. 25 (2006) 5527-5538
-
(2006)
EMBO J.
, vol.25
, pp. 5527-5538
-
-
Yang, Y.G.1
Saidi, A.2
Frappart, P.O.3
Min, W.4
Barrucand, C.5
Dumon-Jones, V.6
Michelon, J.7
Herceg, Z.8
Wang, Z.Q.9
-
54
-
-
0032721091
-
The Mre11-Rad50-Xrs2 protein complex facilitates homologous recombination-based double-strand break repair in Saccharomyces cerevisiae
-
Bressan D.A., Baxter B.K., and Petrini J.H. The Mre11-Rad50-Xrs2 protein complex facilitates homologous recombination-based double-strand break repair in Saccharomyces cerevisiae. Mol. Cell. Biol. 19 (1999) 7681-7687
-
(1999)
Mol. Cell. Biol.
, vol.19
, pp. 7681-7687
-
-
Bressan, D.A.1
Baxter, B.K.2
Petrini, J.H.3
-
55
-
-
0032931844
-
The nuclease activity of Mre11 is required for meiosis but not for mating type switching, end joining, or telomere maintenance
-
Moreau S., Ferguson J.R., and Symington L.S. The nuclease activity of Mre11 is required for meiosis but not for mating type switching, end joining, or telomere maintenance. Mol. Cell. Biol. 19 (1999) 556-566
-
(1999)
Mol. Cell. Biol.
, vol.19
, pp. 556-566
-
-
Moreau, S.1
Ferguson, J.R.2
Symington, L.S.3
-
56
-
-
1942538492
-
ATM and DNA-PK function redundantly to phosphorylate H2AX after exposure to ionizing radiation
-
Stiff T., O'Driscoll M., Rief N., Iwabuchi K., Lobrich M., and Jeggo P.A. ATM and DNA-PK function redundantly to phosphorylate H2AX after exposure to ionizing radiation. Cancer Res. 64 (2004) 2390-2396
-
(2004)
Cancer Res.
, vol.64
, pp. 2390-2396
-
-
Stiff, T.1
O'Driscoll, M.2
Rief, N.3
Iwabuchi, K.4
Lobrich, M.5
Jeggo, P.A.6
-
57
-
-
0343280013
-
A critical role for histone H2AX in recruitment of repair factors to nuclear foci after DNA damage
-
Paull T.T., Rogakou E.P., Yamazaki V., Kirchgessner C.U., Gellert M., and Bonner W.M. A critical role for histone H2AX in recruitment of repair factors to nuclear foci after DNA damage. Curr. Biol. 10 (2000) 886-895
-
(2000)
Curr. Biol.
, vol.10
, pp. 886-895
-
-
Paull, T.T.1
Rogakou, E.P.2
Yamazaki, V.3
Kirchgessner, C.U.4
Gellert, M.5
Bonner, W.M.6
-
58
-
-
0037711771
-
Histone H2AX phosphorylation is dispensable for the initial recognition of DNA breaks
-
Celeste A., Fernandez-Capetillo O., Kruhlak M.J., Pilch D.R., Staudt D.W., Lee A., Bonner R.F., Bonner W.M., and Nussenzweig A. Histone H2AX phosphorylation is dispensable for the initial recognition of DNA breaks. Nat. Cell Biol. 5 (2003) 675-679
-
(2003)
Nat. Cell Biol.
, vol.5
, pp. 675-679
-
-
Celeste, A.1
Fernandez-Capetillo, O.2
Kruhlak, M.J.3
Pilch, D.R.4
Staudt, D.W.5
Lee, A.6
Bonner, R.F.7
Bonner, W.M.8
Nussenzweig, A.9
-
59
-
-
0037012845
-
Genomic instability in mice lacking histone H2AX
-
Celeste A., Petersen S., Romanienko P.J., Fernandez-Capetillo O., Chen H.T., Sedelnikova O.A., Reina-San-Martin B., Coppola V., Meffre E., Difilippantonio M.J., et al. Genomic instability in mice lacking histone H2AX. Science 296 (2002) 922-927
-
(2002)
Science
, vol.296
, pp. 922-927
-
-
Celeste, A.1
Petersen, S.2
Romanienko, P.J.3
Fernandez-Capetillo, O.4
Chen, H.T.5
Sedelnikova, O.A.6
Reina-San-Martin, B.7
Coppola, V.8
Meffre, E.9
Difilippantonio, M.J.10
-
60
-
-
29244434544
-
MDC1 directly binds phosphorylated histone H2AX to regulate cellular responses to DNA double-strand breaks
-
Stucki M., Clapperton J.A., Mohammad D., Yaffe M.B., Smerdon S.J., and Jackson S.P. MDC1 directly binds phosphorylated histone H2AX to regulate cellular responses to DNA double-strand breaks. Cell 123 (2005) 1213-1226
-
(2005)
Cell
, vol.123
, pp. 1213-1226
-
-
Stucki, M.1
Clapperton, J.A.2
Mohammad, D.3
Yaffe, M.B.4
Smerdon, S.J.5
Jackson, S.P.6
-
61
-
-
30744465308
-
MDC1 maintains genomic stability by participating in the amplification of ATM-dependent DNA damage signals
-
Lou Z., Minter-Dykhouse K., Franco S., Gostissa M., Rivera M.A., Celeste A., Manis J.P., van Deursen J., Nussenzweig A., Paull T.T., et al. MDC1 maintains genomic stability by participating in the amplification of ATM-dependent DNA damage signals. Mol. Cell 21 (2006) 187-200
-
(2006)
Mol. Cell
, vol.21
, pp. 187-200
-
-
Lou, Z.1
Minter-Dykhouse, K.2
Franco, S.3
Gostissa, M.4
Rivera, M.A.5
Celeste, A.6
Manis, J.P.7
van Deursen, J.8
Nussenzweig, A.9
Paull, T.T.10
-
62
-
-
22944462083
-
Dynamic assembly and sustained retention of 53BP1 at the sites of DNA damage are controlled by Mdc1/NFBD1
-
Bekker-Jensen S., Lukas C., Melander F., Bartek J., and Lukas J. Dynamic assembly and sustained retention of 53BP1 at the sites of DNA damage are controlled by Mdc1/NFBD1. J. Cell Biol. 170 (2005) 201-211
-
(2005)
J. Cell Biol.
, vol.170
, pp. 201-211
-
-
Bekker-Jensen, S.1
Lukas, C.2
Melander, F.3
Bartek, J.4
Lukas, J.5
-
63
-
-
25444465151
-
Structure of the BRCT repeat domain of MDC1 and its specificity for the free COOH-terminal end of the gamma-H2AX histone tail
-
Lee M.S., Edwards R.A., Thede G.L., and Glover J.N. Structure of the BRCT repeat domain of MDC1 and its specificity for the free COOH-terminal end of the gamma-H2AX histone tail. J. Biol. Chem. 280 (2005) 32053-32056
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 32053-32056
-
-
Lee, M.S.1
Edwards, R.A.2
Thede, G.L.3
Glover, J.N.4
-
64
-
-
48649100438
-
Phospho-dependent interactions between NBS1 and MDC1 mediate chromatin retention of the MRN complex at sites of DNA damage
-
Chapman J.R., and Jackson S.P. Phospho-dependent interactions between NBS1 and MDC1 mediate chromatin retention of the MRN complex at sites of DNA damage. EMBO Rep. 9 (2008) 795-801
-
(2008)
EMBO Rep.
, vol.9
, pp. 795-801
-
-
Chapman, J.R.1
Jackson, S.P.2
-
65
-
-
42449115711
-
Constitutive phosphorylation of MDC1 physically links the MRE11-RAD50-NBS1 complex to damaged chromatin
-
Spycher C., Miller E.S., Townsend K., Pavic L., Morrice N.A., Janscak P., Stewart G.S., and Stucki M. Constitutive phosphorylation of MDC1 physically links the MRE11-RAD50-NBS1 complex to damaged chromatin. J. Cell Biol. 181 (2008) 227-240
-
(2008)
J. Cell Biol.
, vol.181
, pp. 227-240
-
-
Spycher, C.1
Miller, E.S.2
Townsend, K.3
Pavic, L.4
Morrice, N.A.5
Janscak, P.6
Stewart, G.S.7
Stucki, M.8
-
66
-
-
42449086413
-
Phosphorylation of SDT repeats in the MDC1 N terminus triggers retention of NBS1 at the DNA damage-modified chromatin
-
Melander F., Bekker-Jensen S., Falck J., Bartek J., Mailand N., and Lukas J. Phosphorylation of SDT repeats in the MDC1 N terminus triggers retention of NBS1 at the DNA damage-modified chromatin. J. Cell Biol. 181 (2008) 213-226
-
(2008)
J. Cell Biol.
, vol.181
, pp. 213-226
-
-
Melander, F.1
Bekker-Jensen, S.2
Falck, J.3
Bartek, J.4
Mailand, N.5
Lukas, J.6
-
67
-
-
0037468169
-
MDC1 is required for the intra-S-phase DNA damage checkpoint
-
Goldberg M., Stucki M., Falck J., D'Amours D., Rahman D., Pappin D., Bartek J., and Jackson S.P. MDC1 is required for the intra-S-phase DNA damage checkpoint. Nature 421 (2003) 952-956
-
(2003)
Nature
, vol.421
, pp. 952-956
-
-
Goldberg, M.1
Stucki, M.2
Falck, J.3
D'Amours, D.4
Rahman, D.5
Pappin, D.6
Bartek, J.7
Jackson, S.P.8
-
68
-
-
0037468192
-
MDC1 is a mediator of the mammalian DNA damage checkpoint
-
Stewart G.S., Wang B., Bignell C.R., Taylor A.M., and Elledge S.J. MDC1 is a mediator of the mammalian DNA damage checkpoint. Nature 421 (2003) 961-966
-
(2003)
Nature
, vol.421
, pp. 961-966
-
-
Stewart, G.S.1
Wang, B.2
Bignell, C.R.3
Taylor, A.M.4
Elledge, S.J.5
-
69
-
-
36248966246
-
RNF8 ubiquitylates histones at DNA double-strand breaks and promotes assembly of repair proteins
-
Mailand N., Bekker-Jensen S., Faustrup H., Melander F., Bartek J., Lukas C., and Lukas J. RNF8 ubiquitylates histones at DNA double-strand breaks and promotes assembly of repair proteins. Cell 131 (2007) 887-900
-
(2007)
Cell
, vol.131
, pp. 887-900
-
-
Mailand, N.1
Bekker-Jensen, S.2
Faustrup, H.3
Melander, F.4
Bartek, J.5
Lukas, C.6
Lukas, J.7
-
70
-
-
36749084931
-
Orchestration of the DNA-damage response by the RNF8 ubiquitin ligase
-
Kolas N.K., Chapman J.R., Nakada S., Ylanko J., Chahwan R., Sweeney F.D., Panier S., Mendez M., Wildenhain J., Thomson T.M., et al. Orchestration of the DNA-damage response by the RNF8 ubiquitin ligase. Science 318 (2007) 1637-1640
-
(2007)
Science
, vol.318
, pp. 1637-1640
-
-
Kolas, N.K.1
Chapman, J.R.2
Nakada, S.3
Ylanko, J.4
Chahwan, R.5
Sweeney, F.D.6
Panier, S.7
Mendez, M.8
Wildenhain, J.9
Thomson, T.M.10
-
71
-
-
36249031962
-
RNF8 transduces the DNA-damage signal via histone ubiquitylation and checkpoint protein assembly
-
Huen M.S., Grant R., Manke I., Minn K., Yu X., Yaffe M.B., and Chen J. RNF8 transduces the DNA-damage signal via histone ubiquitylation and checkpoint protein assembly. Cell 131 (2007) 901-914
-
(2007)
Cell
, vol.131
, pp. 901-914
-
-
Huen, M.S.1
Grant, R.2
Manke, I.3
Minn, K.4
Yu, X.5
Yaffe, M.B.6
Chen, J.7
-
72
-
-
34249949779
-
RAP80 targets BRCA1 to specific ubiquitin structures at DNA damage sites
-
Sobhian B., Shao G., Lilli D.R., Culhane A.C., Moreau L.A., Xia B., Livingston D.M., and Greenberg R.A. RAP80 targets BRCA1 to specific ubiquitin structures at DNA damage sites. Science 316 (2007) 1198-1202
-
(2007)
Science
, vol.316
, pp. 1198-1202
-
-
Sobhian, B.1
Shao, G.2
Lilli, D.R.3
Culhane, A.C.4
Moreau, L.A.5
Xia, B.6
Livingston, D.M.7
Greenberg, R.A.8
-
73
-
-
59249095962
-
Histone ubiquitination associates with BRCA1-dependent DNA damage response
-
Wu J., Huen M.S., Lu L.Y., Ye L., Dou Y., Ljungman M., Chen J., and Yu X. Histone ubiquitination associates with BRCA1-dependent DNA damage response. Mol. Cell. Biol. 29 (2008) 849-860
-
(2008)
Mol. Cell. Biol.
, vol.29
, pp. 849-860
-
-
Wu, J.1
Huen, M.S.2
Lu, L.Y.3
Ye, L.4
Dou, Y.5
Ljungman, M.6
Chen, J.7
Yu, X.8
-
74
-
-
0032566753
-
The C-terminal (BRCT) domains of BRCA1 interact in vivo with CtIP, a protein implicated in the CtBP pathway of transcriptional repression
-
Yu X., Wu L.C., Bowcock A.M., Aronheim A., and Baer R. The C-terminal (BRCT) domains of BRCA1 interact in vivo with CtIP, a protein implicated in the CtBP pathway of transcriptional repression. J. Biol. Chem. 273 (1998) 25388-25392
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 25388-25392
-
-
Yu, X.1
Wu, L.C.2
Bowcock, A.M.3
Aronheim, A.4
Baer, R.5
-
75
-
-
34249950879
-
Ubiquitin-binding protein RAP80 mediates BRCA1-dependent DNA damage response
-
Kim H., Chen J., and Yu X. Ubiquitin-binding protein RAP80 mediates BRCA1-dependent DNA damage response. Science 316 (2007) 1202-1205
-
(2007)
Science
, vol.316
, pp. 1202-1205
-
-
Kim, H.1
Chen, J.2
Yu, X.3
-
76
-
-
34249946686
-
Abraxas and RAP80 form a BRCA1 protein complex required for the DNA damage response
-
Wang B., Matsuoka S., Ballif B.A., Zhang D., Smogorzewska A., Gygi S.P., and Elledge S.J. Abraxas and RAP80 form a BRCA1 protein complex required for the DNA damage response. Science 316 (2007) 1194-1198
-
(2007)
Science
, vol.316
, pp. 1194-1198
-
-
Wang, B.1
Matsuoka, S.2
Ballif, B.A.3
Zhang, D.4
Smogorzewska, A.5
Gygi, S.P.6
Elledge, S.J.7
-
77
-
-
36749025467
-
Ubc13/Rnf8 ubiquitin ligases control foci formation of the Rap80/Abraxas/Brca1/Brcc36 complex in response to DNA damage
-
Wang B., and Elledge S.J. Ubc13/Rnf8 ubiquitin ligases control foci formation of the Rap80/Abraxas/Brca1/Brcc36 complex in response to DNA damage. Proc. Natl. Acad. Sci. U.S.A. 104 (2007) 20759-20763
-
(2007)
Proc. Natl. Acad. Sci. U.S.A.
, vol.104
, pp. 20759-20763
-
-
Wang, B.1
Elledge, S.J.2
-
78
-
-
10544231876
-
Identification of a RING protein that can interact in vivo with the BRCA1 gene product
-
Wu L.C., Wang Z.W., Tsan J.T., Spillman M.A., Phung A., Xu X.L., Yang M.C., Hwang L.Y., Bowcock A.M., and Baer R. Identification of a RING protein that can interact in vivo with the BRCA1 gene product. Nat. Genet. 14 (1996) 430-440
-
(1996)
Nat. Genet.
, vol.14
, pp. 430-440
-
-
Wu, L.C.1
Wang, Z.W.2
Tsan, J.T.3
Spillman, M.A.4
Phung, A.5
Xu, X.L.6
Yang, M.C.7
Hwang, L.Y.8
Bowcock, A.M.9
Baer, R.10
-
79
-
-
0035805582
-
The RING heterodimer BRCA1-BARD1 is a ubiquitin ligase inactivated by a breast cancer-derived mutation
-
Hashizume R., Fukuda M., Maeda I., Nishikawa H., Oyake D., Yabuki Y., Ogata H., and Ohta T. The RING heterodimer BRCA1-BARD1 is a ubiquitin ligase inactivated by a breast cancer-derived mutation. J. Biol. Chem. 276 (2001) 14537-14540
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 14537-14540
-
-
Hashizume, R.1
Fukuda, M.2
Maeda, I.3
Nishikawa, H.4
Oyake, D.5
Yabuki, Y.6
Ogata, H.7
Ohta, T.8
-
80
-
-
20644461718
-
BACH1, a novel helicase-like protein, interacts directly with BRCA1 and contributes to its DNA repair function
-
Cantor S.B., Bell D.W., Ganesan S., Kass E.M., Drapkin R., Grossman S., Wahrer D.C., Sgroi D.C., Lane W.S., Haber D.A., et al. BACH1, a novel helicase-like protein, interacts directly with BRCA1 and contributes to its DNA repair function. Cell 105 (2001) 149-160
-
(2001)
Cell
, vol.105
, pp. 149-160
-
-
Cantor, S.B.1
Bell, D.W.2
Ganesan, S.3
Kass, E.M.4
Drapkin, R.5
Grossman, S.6
Wahrer, D.C.7
Sgroi, D.C.8
Lane, W.S.9
Haber, D.A.10
-
81
-
-
34547655427
-
CCDC98 is a BRCA1-BRCT domain-binding protein involved in the DNA damage response
-
Kim H., Huang J., and Chen J. CCDC98 is a BRCA1-BRCT domain-binding protein involved in the DNA damage response. Nat. Struct. Mol. Biol. 14 (2007) 710-715
-
(2007)
Nat. Struct. Mol. Biol.
, vol.14
, pp. 710-715
-
-
Kim, H.1
Huang, J.2
Chen, J.3
-
82
-
-
29944434644
-
Multifactorial contributions to an acute DNA damage response by BRCA1/BARD1-containing complexes
-
Greenberg R.A., Sobhian B., Pathania S., Cantor S.B., Nakatani Y., and Livingston D.M. Multifactorial contributions to an acute DNA damage response by BRCA1/BARD1-containing complexes. Genes Dev. 20 (2006) 34-46
-
(2006)
Genes Dev.
, vol.20
, pp. 34-46
-
-
Greenberg, R.A.1
Sobhian, B.2
Pathania, S.3
Cantor, S.B.4
Nakatani, Y.5
Livingston, D.M.6
-
83
-
-
33745614048
-
BRCA1 ubiquitinates its phosphorylation-dependent binding partner CtIP
-
Yu X., Fu S., Lai M., Baer R., and Chen J. BRCA1 ubiquitinates its phosphorylation-dependent binding partner CtIP. Genes Dev. 20 (2006) 1721-1726
-
(2006)
Genes Dev.
, vol.20
, pp. 1721-1726
-
-
Yu, X.1
Fu, S.2
Lai, M.3
Baer, R.4
Chen, J.5
-
84
-
-
50449098473
-
New players in the BRCA1-mediated DNA damage responsive pathway
-
Kim H., and Chen J. New players in the BRCA1-mediated DNA damage responsive pathway. Mol. Cells 25 (2008) 457-461
-
(2008)
Mol. Cells
, vol.25
, pp. 457-461
-
-
Kim, H.1
Chen, J.2
-
85
-
-
33845666681
-
Structural basis for the methylation state-specific recognition of histone H4-K20 by 53BP1 and Crb2 in DNA repair
-
Botuyan M.V., Lee J., Ward I.M., Kim J.E., Thompson J.R., Chen J., and Mer G. Structural basis for the methylation state-specific recognition of histone H4-K20 by 53BP1 and Crb2 in DNA repair. Cell 127 (2006) 1361-1373
-
(2006)
Cell
, vol.127
, pp. 1361-1373
-
-
Botuyan, M.V.1
Lee, J.2
Ward, I.M.3
Kim, J.E.4
Thompson, J.R.5
Chen, J.6
Mer, G.7
-
86
-
-
33645502395
-
Tudor, MBT and chromo domains gauge the degree of lysine methylation
-
Kim J., Daniel J., Espejo A., Lake A., Krishna M., Xia L., Zhang Y., and Bedford M.T. Tudor, MBT and chromo domains gauge the degree of lysine methylation. EMBO Rep. 7 (2006) 397-403
-
(2006)
EMBO Rep.
, vol.7
, pp. 397-403
-
-
Kim, J.1
Daniel, J.2
Espejo, A.3
Lake, A.4
Krishna, M.5
Xia, L.6
Zhang, Y.7
Bedford, M.T.8
-
87
-
-
9244252580
-
Methylated lysine 79 of histone H3 targets 53BP1 to DNA double-strand breaks
-
Huyen Y., Zgheib O., Ditullio Jr. R.A., Gorgoulis V.G., Zacharatos P., Petty T.J., Sheston E.A., Mellert H.S., Stavridi E.S., and Halazonetis T.D. Methylated lysine 79 of histone H3 targets 53BP1 to DNA double-strand breaks. Nature 432 (2004) 406-411
-
(2004)
Nature
, vol.432
, pp. 406-411
-
-
Huyen, Y.1
Zgheib, O.2
Ditullio Jr., R.A.3
Gorgoulis, V.G.4
Zacharatos, P.5
Petty, T.J.6
Sheston, E.A.7
Mellert, H.S.8
Stavridi, E.S.9
Halazonetis, T.D.10
-
88
-
-
0036500691
-
Structure of the 53BP1 BRCT region bound to p53 and its comparison to the Brca1 BRCT structure
-
Joo W.S., Jeffrey P.D., Cantor S.B., Finnin M.S., Livingston D.M., and Pavletich N.P. Structure of the 53BP1 BRCT region bound to p53 and its comparison to the Brca1 BRCT structure. Genes Dev. 16 (2002) 583-593
-
(2002)
Genes Dev.
, vol.16
, pp. 583-593
-
-
Joo, W.S.1
Jeffrey, P.D.2
Cantor, S.B.3
Finnin, M.S.4
Livingston, D.M.5
Pavletich, N.P.6
-
89
-
-
0034629072
-
DNA damage-induced activation of p53 by the checkpoint kinase Chk2
-
Hirao A., Kong Y.Y., Matsuoka S., Wakeham A., Ruland J., Yoshida H., Liu D., Elledge S.J., and Mak T.W. DNA damage-induced activation of p53 by the checkpoint kinase Chk2. Science 287 (2000) 1824-1827
-
(2000)
Science
, vol.287
, pp. 1824-1827
-
-
Hirao, A.1
Kong, Y.Y.2
Matsuoka, S.3
Wakeham, A.4
Ruland, J.5
Yoshida, H.6
Liu, D.7
Elledge, S.J.8
Mak, T.W.9
-
90
-
-
0035093737
-
DNA double-strand breaks: signaling, repair and the cancer connection
-
Khanna K.K., and Jackson S.P. DNA double-strand breaks: signaling, repair and the cancer connection. Nat. Genet. 27 (2001) 247-254
-
(2001)
Nat. Genet.
, vol.27
, pp. 247-254
-
-
Khanna, K.K.1
Jackson, S.P.2
-
91
-
-
0034177304
-
How to activate p53
-
Caspari T. How to activate p53. Curr. Biol. 10 (2000) R315-R317
-
(2000)
Curr. Biol.
, vol.10
-
-
Caspari, T.1
-
92
-
-
37349096996
-
Distinct roles of chromatin-associated proteins MDC1 and 53BP1 in mammalian double-strand break repair
-
Xie A., Hartlerode A., Stucki M., Odate S., Puget N., Kwok A., Nagaraju G., Yan C., Alt F.W., Chen J., et al. Distinct roles of chromatin-associated proteins MDC1 and 53BP1 in mammalian double-strand break repair. Mol. Cell 28 (2007) 1045-1057
-
(2007)
Mol. Cell
, vol.28
, pp. 1045-1057
-
-
Xie, A.1
Hartlerode, A.2
Stucki, M.3
Odate, S.4
Puget, N.5
Kwok, A.6
Nagaraju, G.7
Yan, C.8
Alt, F.W.9
Chen, J.10
-
93
-
-
0037112212
-
53BP1, a mediator of the DNA damage checkpoint
-
Wang B., Matsuoka S., Carpenter P.B., and Elledge S.J. 53BP1, a mediator of the DNA damage checkpoint. Science 298 (2002) 1435-1438
-
(2002)
Science
, vol.298
, pp. 1435-1438
-
-
Wang, B.1
Matsuoka, S.2
Carpenter, P.B.3
Elledge, S.J.4
-
94
-
-
0032085295
-
The 3′ to 5′ exonuclease activity of Mre 11 facilitates repair of DNA double-strand breaks
-
Paull T.T., and Gellert M. The 3′ to 5′ exonuclease activity of Mre 11 facilitates repair of DNA double-strand breaks. Mol. Cell 1 (1998) 969-979
-
(1998)
Mol. Cell
, vol.1
, pp. 969-979
-
-
Paull, T.T.1
Gellert, M.2
-
95
-
-
55949105327
-
Human exonuclease 1 and BLM helicase interact to resect DNA and initiate DNA repair
-
Nimonkar A.V., Ozsoy A.Z., Genschel J., Modrich P., and Kowalczykowski S.C. Human exonuclease 1 and BLM helicase interact to resect DNA and initiate DNA repair. Proc. Natl. Acad. Sci. U.S.A. 105 (2008) 16906-16911
-
(2008)
Proc. Natl. Acad. Sci. U.S.A.
, vol.105
, pp. 16906-16911
-
-
Nimonkar, A.V.1
Ozsoy, A.Z.2
Genschel, J.3
Modrich, P.4
Kowalczykowski, S.C.5
-
96
-
-
36549060102
-
Human CtIP promotes DNA end resection
-
Sartori A.A., Lukas C., Coates J., Mistrik M., Fu S., Bartek J., Baer R., Lukas J., and Jackson S.P. Human CtIP promotes DNA end resection. Nature 450 (2007) 509-514
-
(2007)
Nature
, vol.450
, pp. 509-514
-
-
Sartori, A.A.1
Lukas, C.2
Coates, J.3
Mistrik, M.4
Fu, S.5
Bartek, J.6
Baer, R.7
Lukas, J.8
Jackson, S.P.9
-
97
-
-
43149118369
-
Cell cycle-dependent complex formation of BRCA1.CtIP.MRN is important for DNA double-strand break repair
-
Chen L., Nievera C.J., Lee A.Y., and Wu X. Cell cycle-dependent complex formation of BRCA1.CtIP.MRN is important for DNA double-strand break repair. J. Biol. Chem. 283 (2008) 7713-7720
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 7713-7720
-
-
Chen, L.1
Nievera, C.J.2
Lee, A.Y.3
Wu, X.4
-
98
-
-
18644367144
-
NBS1 localizes to gamma-H2AX foci through interaction with the FHA/BRCT domain
-
Kobayashi J., Tauchi H., Sakamoto S., Nakamura A., Morishima K., Matsuura S., Kobayashi T., Tamai K., Tanimoto K., and Komatsu K. NBS1 localizes to gamma-H2AX foci through interaction with the FHA/BRCT domain. Curr. Biol. 12 (2002) 1846-1851
-
(2002)
Curr. Biol.
, vol.12
, pp. 1846-1851
-
-
Kobayashi, J.1
Tauchi, H.2
Sakamoto, S.3
Nakamura, A.4
Morishima, K.5
Matsuura, S.6
Kobayashi, T.7
Tamai, K.8
Tanimoto, K.9
Komatsu, K.10
-
99
-
-
0033514993
-
Nuclear foci of mammalian recombination proteins are located at single-stranded DNA regions formed after DNA damage
-
Raderschall E., Golub E.I., and Haaf T. Nuclear foci of mammalian recombination proteins are located at single-stranded DNA regions formed after DNA damage. Proc. Natl. Acad. Sci. U.S.A. 96 (1999) 1921-1926
-
(1999)
Proc. Natl. Acad. Sci. U.S.A.
, vol.96
, pp. 1921-1926
-
-
Raderschall, E.1
Golub, E.I.2
Haaf, T.3
-
100
-
-
0037245862
-
An ATR- and Cdc7-dependent DNA damage checkpoint that inhibits initiation of DNA replication
-
Costanzo V., Shechter D., Lupardus P.J., Cimprich K.A., Gottesman M., and Gautier J. An ATR- and Cdc7-dependent DNA damage checkpoint that inhibits initiation of DNA replication. Mol. Cell 11 (2003) 203-213
-
(2003)
Mol. Cell
, vol.11
, pp. 203-213
-
-
Costanzo, V.1
Shechter, D.2
Lupardus, P.J.3
Cimprich, K.A.4
Gottesman, M.5
Gautier, J.6
-
101
-
-
0037567268
-
Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexes
-
Zou L., and Elledge S.J. Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexes. Science 300 (2003) 1542-1548
-
(2003)
Science
, vol.300
, pp. 1542-1548
-
-
Zou, L.1
Elledge, S.J.2
-
102
-
-
0037080675
-
Regulation of ATR substrate selection by Rad17-dependent loading of Rad9 complexes onto chromatin
-
Zou L., Cortez D., and Elledge S.J. Regulation of ATR substrate selection by Rad17-dependent loading of Rad9 complexes onto chromatin. Genes Dev. 16 (2002) 198-208
-
(2002)
Genes Dev.
, vol.16
, pp. 198-208
-
-
Zou, L.1
Cortez, D.2
Elledge, S.J.3
-
103
-
-
0345564858
-
Replication protein A-mediated recruitment and activation of Rad17 complexes
-
Zou L., Liu D., and Elledge S.J. Replication protein A-mediated recruitment and activation of Rad17 complexes. Proc. Natl. Acad. Sci. U.S.A. 100 (2003) 13827-13832
-
(2003)
Proc. Natl. Acad. Sci. U.S.A.
, vol.100
, pp. 13827-13832
-
-
Zou, L.1
Liu, D.2
Elledge, S.J.3
-
104
-
-
33748780358
-
Replication protein A directs loading of the DNA damage checkpoint clamp to 5′-DNA junctions
-
Majka J., Binz S.K., Wold M.S., and Burgers P.M. Replication protein A directs loading of the DNA damage checkpoint clamp to 5′-DNA junctions. J. Biol. Chem. 281 (2006) 27855-27861
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 27855-27861
-
-
Majka, J.1
Binz, S.K.2
Wold, M.S.3
Burgers, P.M.4
-
105
-
-
0037452605
-
Loading of the human 9-1-1 checkpoint complex onto DNA by the checkpoint clamp loader hRad17-replication factor C complex in vitro
-
Bermudez V.P., Lindsey-Boltz L.A., Cesare A.J., Maniwa Y., Griffith J.D., Hurwitz J., and Sancar A. Loading of the human 9-1-1 checkpoint complex onto DNA by the checkpoint clamp loader hRad17-replication factor C complex in vitro. Proc. Natl. Acad. Sci. U.S.A. 100 (2003) 1633-1638
-
(2003)
Proc. Natl. Acad. Sci. U.S.A.
, vol.100
, pp. 1633-1638
-
-
Bermudez, V.P.1
Lindsey-Boltz, L.A.2
Cesare, A.J.3
Maniwa, Y.4
Griffith, J.D.5
Hurwitz, J.6
Sancar, A.7
-
106
-
-
0035930537
-
Histone H2AX is phosphorylated in an ATR-dependent manner in response to replicational stress
-
Ward I.M., and Chen J. Histone H2AX is phosphorylated in an ATR-dependent manner in response to replicational stress. J. Biol. Chem. 276 (2001) 47759-47762
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 47759-47762
-
-
Ward, I.M.1
Chen, J.2
-
107
-
-
0037341599
-
Distinct spatiotemporal dynamics of mammalian checkpoint regulators induced by DNA damage
-
Lukas C., Falck J., Bartkova J., Bartek J., and Lukas J. Distinct spatiotemporal dynamics of mammalian checkpoint regulators induced by DNA damage. Nat. Cell Biol. 5 (2003) 255-260
-
(2003)
Nat. Cell Biol.
, vol.5
, pp. 255-260
-
-
Lukas, C.1
Falck, J.2
Bartkova, J.3
Bartek, J.4
Lukas, J.5
-
108
-
-
0032527973
-
Rad52 associates with RPA and functions with Rad55 and Rad57 to assemble meiotic recombination complexes
-
Gasior S.L., Wong A.K., Kora Y., Shinohara A., and Bishop D.K. Rad52 associates with RPA and functions with Rad55 and Rad57 to assemble meiotic recombination complexes. Genes Dev. 12 (1998) 2208-2221
-
(1998)
Genes Dev.
, vol.12
, pp. 2208-2221
-
-
Gasior, S.L.1
Wong, A.K.2
Kora, Y.3
Shinohara, A.4
Bishop, D.K.5
-
109
-
-
0037468267
-
BRCA2-dependent and independent formation of RAD51 nuclear foci
-
Tarsounas M., Davies D., and West S.C. BRCA2-dependent and independent formation of RAD51 nuclear foci. Oncogene 22 (2003) 1115-1123
-
(2003)
Oncogene
, vol.22
, pp. 1115-1123
-
-
Tarsounas, M.1
Davies, D.2
West, S.C.3
-
110
-
-
0034232358
-
Coordinated response of mammalian Rad51 and Rad52 to DNA damage
-
Liu Y., and Maizels N. Coordinated response of mammalian Rad51 and Rad52 to DNA damage. EMBO Rep. 11 (2000) 85-90
-
(2000)
EMBO Rep.
, vol.11
, pp. 85-90
-
-
Liu, Y.1
Maizels, N.2
-
111
-
-
38449103060
-
The Fanconi anemia pathway and ubiquitin
-
Jacquemont C., and Taniguchi T. The Fanconi anemia pathway and ubiquitin. BMC Biochem. 8 Suppl. 1 (2007) S10
-
(2007)
BMC Biochem.
, vol.8
, Issue.SUPPL. 1
-
-
Jacquemont, C.1
Taniguchi, T.2
-
112
-
-
18544372595
-
BRCA2 function in DNA binding and recombination from a BRCA2-DSS1-ssDNA structure
-
Yang H., Jeffrey P.D., Miller J., Kinnucan E., Sun Y., Thoma N.H., Zheng N., Chen P.L., Lee W.H., and Pavletich N.P. BRCA2 function in DNA binding and recombination from a BRCA2-DSS1-ssDNA structure. Science 297 (2002) 1837-1848
-
(2002)
Science
, vol.297
, pp. 1837-1848
-
-
Yang, H.1
Jeffrey, P.D.2
Miller, J.3
Kinnucan, E.4
Sun, Y.5
Thoma, N.H.6
Zheng, N.7
Chen, P.L.8
Lee, W.H.9
Pavletich, N.P.10
-
113
-
-
0037427075
-
Interaction between BRCA2 and replication protein A is compromised by a cancer-predisposing mutation in BRCA2
-
Wong J.M., Ionescu D., and Ingles C.J. Interaction between BRCA2 and replication protein A is compromised by a cancer-predisposing mutation in BRCA2. Oncogene 22 (2003) 28-33
-
(2003)
Oncogene
, vol.22
, pp. 28-33
-
-
Wong, J.M.1
Ionescu, D.2
Ingles, C.J.3
-
114
-
-
2942705849
-
Functional interaction of monoubiquitinated FANCD2 and BRCA2/FANCD1 in chromatin
-
Wang X., Andreassen P.R., and D'Andrea A.D. Functional interaction of monoubiquitinated FANCD2 and BRCA2/FANCD1 in chromatin. Mol. Cell. Biol. 24 (2004) 5850-5862
-
(2004)
Mol. Cell. Biol.
, vol.24
, pp. 5850-5862
-
-
Wang, X.1
Andreassen, P.R.2
D'Andrea, A.D.3
-
115
-
-
0033603237
-
Net results of nucleolar dynamics
-
Garcia S.N., and Pillus L. Net results of nucleolar dynamics. Cell 97 (1999) 825-828
-
(1999)
Cell
, vol.97
, pp. 825-828
-
-
Garcia, S.N.1
Pillus, L.2
-
116
-
-
33745200945
-
Control of BRCA2 cellular and clinical functions by a nuclear partner, PALB2
-
Xia B., Sheng Q., Nakanishi K., Ohashi A., Wu J., Christ N., Liu X., Jasin M., Couch F.J., and Livingston D.M. Control of BRCA2 cellular and clinical functions by a nuclear partner, PALB2. Mol. Cell 22 (2006) 719-729
-
(2006)
Mol. Cell
, vol.22
, pp. 719-729
-
-
Xia, B.1
Sheng, Q.2
Nakanishi, K.3
Ohashi, A.4
Wu, J.5
Christ, N.6
Liu, X.7
Jasin, M.8
Couch, F.J.9
Livingston, D.M.10
-
117
-
-
0042671242
-
BRCA1-independent ubiquitination of FANCD2
-
Vandenberg C.J., Gergely F., Ong C.Y., Pace P., Mallery D.L., Hiom K., and Patel K.J. BRCA1-independent ubiquitination of FANCD2. Mol. Cell 12 (2003) 247-254
-
(2003)
Mol. Cell
, vol.12
, pp. 247-254
-
-
Vandenberg, C.J.1
Gergely, F.2
Ong, C.Y.3
Pace, P.4
Mallery, D.L.5
Hiom, K.6
Patel, K.J.7
-
118
-
-
0035105291
-
Interaction of the Fanconi anemia proteins and BRCA1 in a common pathway
-
Garcia-Higuera I., Taniguchi T., Ganesan S., Meyn M.S., Timmers C., Hejna J., Grompe M., and D'Andrea A.D. Interaction of the Fanconi anemia proteins and BRCA1 in a common pathway. Mol. Cell 7 (2001) 249-262
-
(2001)
Mol. Cell
, vol.7
, pp. 249-262
-
-
Garcia-Higuera, I.1
Taniguchi, T.2
Ganesan, S.3
Meyn, M.S.4
Timmers, C.5
Hejna, J.6
Grompe, M.7
D'Andrea, A.D.8
-
119
-
-
3042858785
-
Direct interaction of FANCD2 with BRCA2 in DNA damage response pathways
-
Hussain S., Wilson J.B., Medhurst A.L., Hejna J., Witt E., Ananth S., Davies A., Masson J.Y., Moses R., West S.C., et al. Direct interaction of FANCD2 with BRCA2 in DNA damage response pathways. Hum. Mol. Genet. 13 (2004) 1241-1248
-
(2004)
Hum. Mol. Genet.
, vol.13
, pp. 1241-1248
-
-
Hussain, S.1
Wilson, J.B.2
Medhurst, A.L.3
Hejna, J.4
Witt, E.5
Ananth, S.6
Davies, A.7
Masson, J.Y.8
Moses, R.9
West, S.C.10
-
120
-
-
0035933877
-
XRCC2 is a nuclear RAD51-like protein required for damage-dependent RAD51 focus formation without the need for ATP binding
-
O'Regan P., Wilson C., Townsend S., and Thacker J. XRCC2 is a nuclear RAD51-like protein required for damage-dependent RAD51 focus formation without the need for ATP binding. J. Biol. Chem. 276 (2001) 22148-22153
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 22148-22153
-
-
O'Regan, P.1
Wilson, C.2
Townsend, S.3
Thacker, J.4
-
121
-
-
0035018530
-
Impaired DNA damage response in cells expressing an exon 11-deleted murine Brca1 variant that localizes to nuclear foci
-
Huber L.J., Yang T.W., Sarkisian C.J., Master S.R., Deng C.X., and Chodosh L.A. Impaired DNA damage response in cells expressing an exon 11-deleted murine Brca1 variant that localizes to nuclear foci. Mol. Cell. Biol. 21 (2001) 4005-4015
-
(2001)
Mol. Cell. Biol.
, vol.21
, pp. 4005-4015
-
-
Huber, L.J.1
Yang, T.W.2
Sarkisian, C.J.3
Master, S.R.4
Deng, C.X.5
Chodosh, L.A.6
-
122
-
-
0034604716
-
The breast cancer susceptibility gene BRCA1 is required for subnuclear assembly of Rad51 and survival following treatment with the DNA cross-linking agent cisplatin
-
Bhattacharyya A., Ear U.S., Koller B.H., Weichselbaum R.R., and Bishop D.K. The breast cancer susceptibility gene BRCA1 is required for subnuclear assembly of Rad51 and survival following treatment with the DNA cross-linking agent cisplatin. J. Biol. Chem. 275 (2000) 23899-23903
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 23899-23903
-
-
Bhattacharyya, A.1
Ear, U.S.2
Koller, B.H.3
Weichselbaum, R.R.4
Bishop, D.K.5
-
123
-
-
0033602450
-
Mouse Rad54 affects DNA conformation and DNA-damage-induced Rad51 foci formation
-
Tan T.L., Essers J., Citterio E., Swagemakers S.M., de Wit J., Benson F.E., Hoeijmakers J.H., and Kanaar R. Mouse Rad54 affects DNA conformation and DNA-damage-induced Rad51 foci formation. Curr. Biol. 9 (1999) 325-328
-
(1999)
Curr. Biol.
, vol.9
, pp. 325-328
-
-
Tan, T.L.1
Essers, J.2
Citterio, E.3
Swagemakers, S.M.4
de Wit, J.5
Benson, F.E.6
Hoeijmakers, J.H.7
Kanaar, R.8
-
124
-
-
0032555591
-
Xrcc3 is required for assembly of Rad51 complexes in vivo
-
Bishop D.K., Ear U., Bhattacharyya A., Calderone C., Beckett M., Weichselbaum R.R., and Shinohara A. Xrcc3 is required for assembly of Rad51 complexes in vivo. J. Biol. Chem. 273 (1998) 21482-21488
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 21482-21488
-
-
Bishop, D.K.1
Ear, U.2
Bhattacharyya, A.3
Calderone, C.4
Beckett, M.5
Weichselbaum, R.R.6
Shinohara, A.7
-
126
-
-
19444367726
-
Ionizing radiation-induced foci formation of mammalian Rad51 and Rad54 depends on the Rad51 paralogs, but not on Rad52
-
van Veelen L.R., Essers J., van de Rakt M.W., Odijk H., Pastink A., Zdzienicka M.Z., Paulusma C.C., and Kanaar R. Ionizing radiation-induced foci formation of mammalian Rad51 and Rad54 depends on the Rad51 paralogs, but not on Rad52. Mutat. Res. 574 (2005) 34-49
-
(2005)
Mutat. Res.
, vol.574
, pp. 34-49
-
-
van Veelen, L.R.1
Essers, J.2
van de Rakt, M.W.3
Odijk, H.4
Pastink, A.5
Zdzienicka, M.Z.6
Paulusma, C.C.7
Kanaar, R.8
-
127
-
-
0035893365
-
Identification and purification of two distinct complexes containing the five RAD51 paralogs
-
Masson J.Y., Tarsounas M.C., Stasiak A.Z., Stasiak A., Shah R., McIlwraith M.J., Benson F.E., and West S.C. Identification and purification of two distinct complexes containing the five RAD51 paralogs. Genes Dev. 15 (2001) 3296-3307
-
(2001)
Genes Dev.
, vol.15
, pp. 3296-3307
-
-
Masson, J.Y.1
Tarsounas, M.C.2
Stasiak, A.Z.3
Stasiak, A.4
Shah, R.5
McIlwraith, M.J.6
Benson, F.E.7
West, S.C.8
-
128
-
-
0034596020
-
Evidence for simultaneous protein interactions between human Rad51 paralogs
-
Schild D., Lio Y.C., Collins D.W., Tsomondo T., and Chen D.J. Evidence for simultaneous protein interactions between human Rad51 paralogs. J. Biol. Chem. 275 (2000) 16443-16449
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 16443-16449
-
-
Schild, D.1
Lio, Y.C.2
Collins, D.W.3
Tsomondo, T.4
Chen, D.J.5
-
129
-
-
0032061317
-
XRCC2 and XRCC3, new human Rad51-family members, promote chromosome stability and protect against DNA cross-links and other damages
-
Liu N., Lamerdin J.E., Tebbs R.S., Schild D., Tucker J.D., Shen M.R., Brookman K.W., Siciliano M.J., Walter C.A., Fan W., et al. XRCC2 and XRCC3, new human Rad51-family members, promote chromosome stability and protect against DNA cross-links and other damages. Mol. Cell 1 (1998) 783-793
-
(1998)
Mol. Cell
, vol.1
, pp. 783-793
-
-
Liu, N.1
Lamerdin, J.E.2
Tebbs, R.S.3
Schild, D.4
Tucker, J.D.5
Shen, M.R.6
Brookman, K.W.7
Siciliano, M.J.8
Walter, C.A.9
Fan, W.10
-
130
-
-
16644377060
-
Xrcc3 is recruited to DNA double strand breaks early and independent of Rad51
-
Forget A.L., Bennett B.T., and Knight K.L. Xrcc3 is recruited to DNA double strand breaks early and independent of Rad51. J. Cell. Biochem. 93 (2004) 429-436
-
(2004)
J. Cell. Biochem.
, vol.93
, pp. 429-436
-
-
Forget, A.L.1
Bennett, B.T.2
Knight, K.L.3
-
131
-
-
0032403121
-
Interaction of human Rad51 recombination protein with single-stranded DNA binding protein, RPA
-
Golub E.I., Gupta R.C., Haaf T., Wold M.S., and Radding C.M. Interaction of human Rad51 recombination protein with single-stranded DNA binding protein, RPA. Nucleic Acids Res. 26 (1998) 5388-5393
-
(1998)
Nucleic Acids Res.
, vol.26
, pp. 5388-5393
-
-
Golub, E.I.1
Gupta, R.C.2
Haaf, T.3
Wold, M.S.4
Radding, C.M.5
-
132
-
-
34548573123
-
RPA mediates recombination repair during replication stress and is displaced from DNA by checkpoint signalling in human cells
-
Sleeth K.M., Sorensen C.S., Issaeva N., Dziegielewski J., Bartek J., and Helleday T. RPA mediates recombination repair during replication stress and is displaced from DNA by checkpoint signalling in human cells. J. Mol. Biol. 373 (2007) 38-47
-
(2007)
J. Mol. Biol.
, vol.373
, pp. 38-47
-
-
Sleeth, K.M.1
Sorensen, C.S.2
Issaeva, N.3
Dziegielewski, J.4
Bartek, J.5
Helleday, T.6
-
133
-
-
0034714242
-
A novel human Rad54 homologue, Rad54B, associates with Rad51
-
Tanaka K., Hiramoto T., Fukuda T., and Miyagawa K. A novel human Rad54 homologue, Rad54B, associates with Rad51. J. Biol. Chem. 275 (2000) 26316-26321
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 26316-26321
-
-
Tanaka, K.1
Hiramoto, T.2
Fukuda, T.3
Miyagawa, K.4
-
134
-
-
33846141125
-
Werner syndrome protein participates in a complex with RAD51, RAD54, RAD54B and ATR in response to ICL-induced replication arrest
-
Otterlei M., Bruheim P., Ahn B., Bussen W., Karmakar P., Baynton K., and Bohr V.A. Werner syndrome protein participates in a complex with RAD51, RAD54, RAD54B and ATR in response to ICL-induced replication arrest. J. Cell Sci. 119 (2006) 5137-5146
-
(2006)
J. Cell Sci.
, vol.119
, pp. 5137-5146
-
-
Otterlei, M.1
Bruheim, P.2
Ahn, B.3
Bussen, W.4
Karmakar, P.5
Baynton, K.6
Bohr, V.A.7
-
135
-
-
14244255612
-
Werner syndrome protein associates with gamma H2AX in a manner that depends upon Nbs1
-
Cheng W.H., Sakamoto S., Fox J.T., Komatsu K., Carney J., and Bohr V.A. Werner syndrome protein associates with gamma H2AX in a manner that depends upon Nbs1. FEBS Lett. 579 (2005) 1350-1356
-
(2005)
FEBS Lett.
, vol.579
, pp. 1350-1356
-
-
Cheng, W.H.1
Sakamoto, S.2
Fox, J.T.3
Komatsu, K.4
Carney, J.5
Bohr, V.A.6
-
136
-
-
0141480945
-
WRN interacts physically and functionally with the recombination mediator protein RAD52
-
Baynton K., Otterlei M., Bjoras M., von Kobbe C., Bohr V.A., and Seeberg E. WRN interacts physically and functionally with the recombination mediator protein RAD52. J. Biol. Chem. 278 (2003) 36476-36486
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 36476-36486
-
-
Baynton, K.1
Otterlei, M.2
Bjoras, M.3
von Kobbe, C.4
Bohr, V.A.5
Seeberg, E.6
-
137
-
-
17944373792
-
Rad52 partially substitutes for the Rad51 paralog XRCC3 in maintaining chromosomal integrity in vertebrate cells
-
Fujimori A., Tachiiri S., Sonoda E., Thompson L.H., Dhar P.K., Hiraoka M., Takeda S., Zhang Y., Reth M., and Takata M. Rad52 partially substitutes for the Rad51 paralog XRCC3 in maintaining chromosomal integrity in vertebrate cells. EMBO J. 20 (2001) 5513-5520
-
(2001)
EMBO J.
, vol.20
, pp. 5513-5520
-
-
Fujimori, A.1
Tachiiri, S.2
Sonoda, E.3
Thompson, L.H.4
Dhar, P.K.5
Hiraoka, M.6
Takeda, S.7
Zhang, Y.8
Reth, M.9
Takata, M.10
-
138
-
-
0029768921
-
Physical interaction between human RAD52 and RPA is required for homologous recombination in mammalian cells
-
Park M.S., Ludwig D.L., Stigger E., and Lee S.H. Physical interaction between human RAD52 and RPA is required for homologous recombination in mammalian cells. J. Biol. Chem. 271 (1996) 18996-19000
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 18996-19000
-
-
Park, M.S.1
Ludwig, D.L.2
Stigger, E.3
Lee, S.H.4
-
139
-
-
47949092912
-
Saccharomyces cerevisiae ATM orthologue suppresses break-induced chromosome translocations
-
Lee K., Zhang Y., and Lee S.E. Saccharomyces cerevisiae ATM orthologue suppresses break-induced chromosome translocations. Nature 454 (2008) 543-546
-
(2008)
Nature
, vol.454
, pp. 543-546
-
-
Lee, K.1
Zhang, Y.2
Lee, S.E.3
-
140
-
-
19344371406
-
Mre11 assembles linear DNA fragments into DNA damage signaling complexes
-
Costanzo V., Paull T., Gottesman M., and Gautier J. Mre11 assembles linear DNA fragments into DNA damage signaling complexes. PLoS Biol. 2 (2004) 600-609
-
(2004)
PLoS Biol.
, vol.2
, pp. 600-609
-
-
Costanzo, V.1
Paull, T.2
Gottesman, M.3
Gautier, J.4
-
141
-
-
0038141976
-
Colocalization of multiple DNA double-strand breaks at a single Rad52 repair centre
-
Lisby M., Mortensen U.H., and Rothstein R. Colocalization of multiple DNA double-strand breaks at a single Rad52 repair centre. Nat. Cell Biol. 5 (2003) 572-577
-
(2003)
Nat. Cell Biol.
, vol.5
, pp. 572-577
-
-
Lisby, M.1
Mortensen, U.H.2
Rothstein, R.3
-
142
-
-
33644905252
-
Changes in chromatin structure and mobility in living cells at sites of DNA double-strand breaks
-
Kruhlak M.J., Celeste A., Dellaire G., Fernandez-Capetillo O., Muller W.G., McNally J.G., Bazett-Jones D.P., and Nussenzweig A. Changes in chromatin structure and mobility in living cells at sites of DNA double-strand breaks. J. Cell Biol. 172 (2006) 823-834
-
(2006)
J. Cell Biol.
, vol.172
, pp. 823-834
-
-
Kruhlak, M.J.1
Celeste, A.2
Dellaire, G.3
Fernandez-Capetillo, O.4
Muller, W.G.5
McNally, J.G.6
Bazett-Jones, D.P.7
Nussenzweig, A.8
-
143
-
-
34447574977
-
Positional stability of single double-strand breaks in mammalian cells
-
Soutoglou E., Dorn J.F., Sengupta K., Jasin M., Nussenzweig A., Ried T., Danuser G., and Misteli T. Positional stability of single double-strand breaks in mammalian cells. Nat. Cell Biol. 9 (2007) 675-682
-
(2007)
Nat. Cell Biol.
, vol.9
, pp. 675-682
-
-
Soutoglou, E.1
Dorn, J.F.2
Sengupta, K.3
Jasin, M.4
Nussenzweig, A.5
Ried, T.6
Danuser, G.7
Misteli, T.8
-
144
-
-
0347988236
-
Dynamics of DNA double-strand breaks revealed by clustering of damaged chromosome domains
-
Aten J.A., Stap J., Krawczyk P.M., van Oven C.H., Hoebe R.A., Essers J., and Kanaar R. Dynamics of DNA double-strand breaks revealed by clustering of damaged chromosome domains. Science 303 (2004) 92-95
-
(2004)
Science
, vol.303
, pp. 92-95
-
-
Aten, J.A.1
Stap, J.2
Krawczyk, P.M.3
van Oven, C.H.4
Hoebe, R.A.5
Essers, J.6
Kanaar, R.7
-
145
-
-
57049132043
-
53BP1 promotes non-homologous end joining of telomeres by increasing chromatin mobility
-
Dimitrova N., Chen Y.C., Spector D.L., and de Lange T. 53BP1 promotes non-homologous end joining of telomeres by increasing chromatin mobility. Nature 456 (2008) 524-528
-
(2008)
Nature
, vol.456
, pp. 524-528
-
-
Dimitrova, N.1
Chen, Y.C.2
Spector, D.L.3
de Lange, T.4
-
146
-
-
34547589577
-
Formation of NHEJ-derived reciprocal chromosomal translocations does not require Ku70
-
Weinstock D.M., Brunet E., and Jasin M. Formation of NHEJ-derived reciprocal chromosomal translocations does not require Ku70. Nat. Cell Biol. 9 (2007) 978-981
-
(2007)
Nat. Cell Biol.
, vol.9
, pp. 978-981
-
-
Weinstock, D.M.1
Brunet, E.2
Jasin, M.3
-
147
-
-
34547591933
-
The Smc5-Smc6 complex and SUMO modification of Rad52 regulates recombinational repair at the ribosomal gene locus
-
Torres-Rosell J., Sunjevaric I., De Piccoli G., Sacher M., Eckert-Boulet N., Reid R., Jentsch S., Rothstein R., Aragon L., and Lisby M. The Smc5-Smc6 complex and SUMO modification of Rad52 regulates recombinational repair at the ribosomal gene locus. Nat. Cell Biol. 9 (2007) 923-931
-
(2007)
Nat. Cell Biol.
, vol.9
, pp. 923-931
-
-
Torres-Rosell, J.1
Sunjevaric, I.2
De Piccoli, G.3
Sacher, M.4
Eckert-Boulet, N.5
Reid, R.6
Jentsch, S.7
Rothstein, R.8
Aragon, L.9
Lisby, M.10
-
148
-
-
54949093203
-
Functional targeting of DNA damage to a nuclear pore-associated SUMO-dependent ubiquitin ligase
-
Nagai S., Dubrana K., Tsai-Pflugfelder M., Davidson M.B., Roberts T.M., Brown G.W., Varela E., Hediger F., Gasser S.M., and Krogan N.J. Functional targeting of DNA damage to a nuclear pore-associated SUMO-dependent ubiquitin ligase. Science 322 (2008) 597-602
-
(2008)
Science
, vol.322
, pp. 597-602
-
-
Nagai, S.1
Dubrana, K.2
Tsai-Pflugfelder, M.3
Davidson, M.B.4
Roberts, T.M.5
Brown, G.W.6
Varela, E.7
Hediger, F.8
Gasser, S.M.9
Krogan, N.J.10
-
149
-
-
49649106438
-
A mechanism for asymmetric segregation of age during yeast budding
-
Shcheprova Z., Baldi S., Frei S.B., Gonnet G., and Barral Y. A mechanism for asymmetric segregation of age during yeast budding. Nature 454 (2008) 728-734
-
(2008)
Nature
, vol.454
, pp. 728-734
-
-
Shcheprova, Z.1
Baldi, S.2
Frei, S.B.3
Gonnet, G.4
Barral, Y.5
-
150
-
-
56949107726
-
A mother's sacrifice: what is she keeping for herself?
-
Henderson K.A., and Gottschling D.E. A mother's sacrifice: what is she keeping for herself?. Curr. Opin. Cell Biol. 20 (2008) 723-728
-
(2008)
Curr. Opin. Cell Biol.
, vol.20
, pp. 723-728
-
-
Henderson, K.A.1
Gottschling, D.E.2
-
151
-
-
37748999305
-
Genome-wide analysis of Rad52 foci reveals diverse mechanisms impacting recombination
-
Alvaro D., Lisby M., and Rothstein R. Genome-wide analysis of Rad52 foci reveals diverse mechanisms impacting recombination. PLoS Genet. 3 (2007) 2439-2449
-
(2007)
PLoS Genet.
, vol.3
, pp. 2439-2449
-
-
Alvaro, D.1
Lisby, M.2
Rothstein, R.3
|