MDC1 maintains genomic stability by participating in the amplification of ATM-dependent DNA damage signals

Molecular Cell

Volumn 21, Issue 2, 2006, Pages 187-200

  Lou, Zhenkun ^a   Minter Dykhouse, Katherine ^a   Franco, Sonia ^b   Gostissa, Monica ^b   Rivera, Melissa A ^c   Celeste, Arkady ^d   Manis, John P ^b   Van Deursen, Jan ^a   Nussenzweig, André ^d   Paull, Tanya T ^c   Alt, Frederick W ^b   Chen, Junjie ^a  

^a MAYO CLINIC   (United States)

^b BOSTON CHILDREN S HOSPITAL   (United States)

^c UNIVERSITY OF TEXAS AT AUSTIN   (United States)

^d NATIONAL CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ATM PROTEIN; CHECKPOINT KINASE 1; DNA; HISTONE H2AX; PROTEIN MDC1; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CHROMOSOMAL INSTABILITY; DNA DAMAGE; DNA FLANKING REGION; DNA REPAIR; DNA STRAND BREAKAGE; EMBRYONIC STEM CELL; FIBROBLAST; GENE AMPLIFICATION; GENOMIC INSTABILITY; GROWTH RETARDATION; IMMUNE DEFICIENCY; MALE INFERTILITY; MOUSE; NONHUMAN; PHENOTYPE; PROTEIN BINDING; PROTEIN INTERACTION; PROTEIN PHOSPHORYLATION; RADIOSENSITIVITY; SIGNAL TRANSDUCTION;

ANIMALS; CELL CYCLE PROTEINS; DNA DAMAGE; DNA REPAIR; DNA-BINDING PROTEINS; FEMALE; GENOMIC INSTABILITY; INFERTILITY, MALE; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MODELS, BIOLOGICAL; NUCLEAR PROTEINS; PROTEIN-SERINE-THREONINE KINASES; SIGNAL TRANSDUCTION; TRANS-ACTIVATORS; TUMOR SUPPRESSOR PROTEINS;

ANIMALIA;

EID: 30744465308     PISSN: 10972765     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molcel.2005.11.025     Document Type: Article

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