메뉴 건너뛰기




Volumn 19, Issue 11, 1999, Pages 7681-7687

The Mre11-Rad50-Xrs2 protein complex facilitates homologous recombination-based double-strand break repair in Saccharomyces cerevisiae

Author keywords

[No Author keywords available]

Indexed keywords

GENE PRODUCT; MUTANT PROTEIN; NUCLEASE; PROTEIN MRE 11; PROTEIN XRS2; RAD50 PROTEIN; UNCLASSIFIED DRUG;

EID: 0032721091     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.19.11.7681     Document Type: Article
Times cited : (236)

References (38)
  • 1
    • 0027476083 scopus 로고
    • Identification of new genes required for meiotic recombination in Saccharomyces cerevisiae
    • Ajimura, M., S.-H. Leem, and H. Ogawa. 1993. Identification of new genes required for meiotic recombination in Saccharomyces cerevisiae. Genetics 133:51-66.
    • (1993) Genetics , vol.133 , pp. 51-66
    • Ajimura, M.1    Leem, S.-H.2    Ogawa, H.3
  • 2
    • 0023392267 scopus 로고
    • A method for gene disruption that allows repeated use of URA3 selection in the construction of multiply disrupted yeast strains
    • Alani, E., L. Cao, and N. Kleckner. 1987. A method for gene disruption that allows repeated use of URA3 selection in the construction of multiply disrupted yeast strains. Genetics 116:541-545.
    • (1987) Genetics , vol.116 , pp. 541-545
    • Alani, E.1    Cao, L.2    Kleckner, N.3
  • 3
    • 0024669753 scopus 로고
    • The yeast RAD50 gene encodes a predicted 153 kD protein containing a purine nucleotide-binding domain and two large heptad repeat regions
    • Alani, E., S. Subbiah, and N. Kleckner. 1989. The yeast RAD50 gene encodes a predicted 153 kD protein containing a purine nucleotide-binding domain and two large heptad repeat regions. Genetics 122:47-57.
    • (1989) Genetics , vol.122 , pp. 47-57
    • Alani, E.1    Subbiah, S.2    Kleckner, N.3
  • 5
    • 0031037649 scopus 로고    scopus 로고
    • DNA double-strand-break sensitivity, DNA replication, and cell cycle arrest phenotypes of Ku-deficient Saccharomyces cerevisiae
    • Barnes, G., and D. Rio. 1997. DNA double-strand-break sensitivity, DNA replication, and cell cycle arrest phenotypes of Ku-deficient Saccharomyces cerevisiae. Proc. Natl. Acad. Sci. USA 94:867-872.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 867-872
    • Barnes, G.1    Rio, D.2
  • 6
    • 0029791694 scopus 로고    scopus 로고
    • Saccharomyces cerevisiae Ku70 potentiates illegitimate DNA double-strand break repair and serves as a barrier to error-prone DNA repair pathways
    • Boulton, S. J., and S. P. Jackson. 1996. Saccharomyces cerevisiae Ku70 potentiates illegitimate DNA double-strand break repair and serves as a barrier to error-prone DNA repair pathways. EMBO J. 15:5093-5103.
    • (1996) EMBO J. , vol.15 , pp. 5093-5103
    • Boulton, S.J.1    Jackson, S.P.2
  • 7
    • 0031664401 scopus 로고    scopus 로고
    • Alteration of N-terminal phosphoesterase motifs inactivates Saccharomyces cerevisiae Mre11
    • Bressan, D. A., H. A. Olivares, B. E. Nelms, and J. H. J. Petrini. 1998. Alteration of N-terminal phosphoesterase motifs inactivates Saccharomyces cerevisiae Mre11. Genetics 150:591-600.
    • (1998) Genetics , vol.150 , pp. 591-600
    • Bressan, D.A.1    Olivares, H.A.2    Nelms, B.E.3    Petrini, J.H.J.4
  • 8
    • 0019187705 scopus 로고
    • Cell-cycle-specific repair of DNA double strand breaks in Saccharomyces cerevisiae
    • Brunborg, G., M. A. Resnick, and D. H. Williamson. 1980. Cell-cycle-specific repair of DNA double strand breaks in Saccharomyces cerevisiae. Radiat. Res. 82:547-558.
    • (1980) Radiat. Res. , vol.82 , pp. 547-558
    • Brunborg, G.1    Resnick, M.A.2    Williamson, D.H.3
  • 9
    • 0018100612 scopus 로고
    • The relevance of the nuclear division cycle to radiosensitivity in yeast
    • Brunborg, G., and D. H. Williamson. 1978. The relevance of the nuclear division cycle to radiosensitivity in yeast. Mol. Gen. Genet. 162:277-286.
    • (1978) Mol. Gen. Genet. , vol.162 , pp. 277-286
    • Brunborg, G.1    Williamson, D.H.2
  • 10
    • 0014295747 scopus 로고
    • Genetic recombination in synchronized cultures of Saccharomyces cerevisiae
    • Esposito, R. E. 1968. Genetic recombination in synchronized cultures of Saccharomyces cerevisiae. Genetics 59:191-210.
    • (1968) Genetics , vol.59 , pp. 191-210
    • Esposito, R.E.1
  • 11
    • 0031888685 scopus 로고    scopus 로고
    • The Saccharomyces cerevisiae RAD9 checkpoint reduces the DNA damage-associated stimulation of directed translations
    • Fasullo, M. T., T. Bennett, P. AhChing, and J. Koudelik. 1998. The Saccharomyces cerevisiae RAD9 checkpoint reduces the DNA damage-associated stimulation of directed translations. Mol. Cell. Biol. 18:1190-1200.
    • (1998) Mol. Cell. Biol. , vol.18 , pp. 1190-1200
    • Fasullo, M.T.1    Bennett, T.2    AhChing, P.3    Koudelik, J.4
  • 12
    • 0032476658 scopus 로고    scopus 로고
    • Distinct roles of two separable in vitro activities of yeast Mre11 in mitotic and meiotic recombination
    • Furuse, M., Y. Nagase, H. Tsubouchi, K. Murakami-Murofushi, T. Shibata, and K. Ohta. 1998. Distinct roles of two separable in vitro activities of yeast Mre11 in mitotic and meiotic recombination. EMBO J. 17:6412-6425.
    • (1998) EMBO J. , vol.17 , pp. 6412-6425
    • Furuse, M.1    Nagase, Y.2    Tsubouchi, H.3    Murakami-Murofushi, K.4    Shibata, T.5    Ohta, K.6
  • 13
    • 0004330520 scopus 로고
    • Academic Press, Inc., San Diego, Calif.
    • Guthrie, C., and G. R. Fink. 1991. Methods in enzymology, vol. 194. Academic Press, Inc., San Diego, Calif.
    • (1991) Methods in Enzymology , vol.194
    • Guthrie, C.1    Fink, G.R.2
  • 14
    • 0032567041 scopus 로고    scopus 로고
    • The many interfaces of Mre11
    • Haber, J. E. 1998. The many interfaces of Mre11. Cell 95:583-586.
    • (1998) Cell , vol.95 , pp. 583-586
    • Haber, J.E.1
  • 15
    • 0032412476 scopus 로고    scopus 로고
    • Mating-type gene switching in Saccharomyces cerevisiae
    • Haber, J. E. 1998. Mating-type gene switching in Saccharomyces cerevisiae. Annu. Rev. Genet. 32:561-599.
    • (1998) Annu. Rev. Genet. , vol.32 , pp. 561-599
    • Haber, J.E.1
  • 16
    • 0021796842 scopus 로고
    • Altered fidelity of mitotic chromosome transmission in cell cycle mutants of S. cerevisiae
    • Hartwell, L. H., and D. Smith. 1985. Altered fidelity of mitotic chromosome transmission in cell cycle mutants of S. cerevisiae. Genetics 110:381-395.
    • (1985) Genetics , vol.110 , pp. 381-395
    • Hartwell, L.H.1    Smith, D.2
  • 17
    • 0020354447 scopus 로고
    • Sites and structures of γ radiation-induced DNA strand breaks
    • Henner, W.D., S. M. Grunberg, and W. A. Haseltine. 1982. Sites and structures of γ radiation-induced DNA strand breaks. J. Biol. Chem. 257:11750-11754.
    • (1982) J. Biol. Chem. , vol.257 , pp. 11750-11754
    • Henner, W.D.1    Grunberg, S.M.2    Haseltine, W.A.3
  • 18
    • 0026759693 scopus 로고
    • XRS2, a DNA repair gene of Saccharomyces cerevisiae, is needed for meiotic recombination
    • Ivanov, E. L., V. G. Korolev, and F. Fabre. 1992. XRS2, a DNA repair gene of Saccharomyces cerevisiae, is needed for meiotic recombination. Genetics 132:651-664.
    • (1992) Genetics , vol.132 , pp. 651-664
    • Ivanov, E.L.1    Korolev, V.G.2    Fabre, F.3
  • 19
    • 0028212415 scopus 로고
    • Mutations in XRS2 and RAD50 delay but do not prevent mating-type switching in Saccharomyces cerevisiae
    • Ivanov, E. L., N. Sugawara, C. I. White, F. Fabre, and J. E. Haber. 1994. Mutations in XRS2 and RAD50 delay but do not prevent mating-type switching in Saccharomyces cerevisiae. Mol. Cell. Biol. 14:3414-3425.
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 3414-3425
    • Ivanov, E.L.1    Sugawara, N.2    White, C.I.3    Fabre, F.4    Haber, J.E.5
  • 20
    • 0026709385 scopus 로고
    • Sister chromatids are preferred over homologs as substrates for recombinational repair in Saccharomyces cerevisiae
    • Kadyk, L. C., and L. H. Hartwell. 1992. Sister chromatids are preferred over homologs as substrates for recombinational repair in Saccharomyces cerevisiae. Genetics 132:387-402.
    • (1992) Genetics , vol.132 , pp. 387-402
    • Kadyk, L.C.1    Hartwell, L.H.2
  • 21
    • 0031151501 scopus 로고    scopus 로고
    • Recombination and joining: Different means to the same ends
    • Kanaar, R., and J. H. J. Hoeijmakers. 1997. Recombination and joining: different means to the same ends. Genes Funct. 1:165-174.
    • (1997) Genes Funct. , vol.1 , pp. 165-174
    • Kanaar, R.1    Hoeijmakers, J.H.J.2
  • 22
    • 0028998597 scopus 로고
    • Collapse and repair of replication forks in Escherichia coli
    • Kuzminov, A. 1995. Collapse and repair of replication forks in Escherichia coli. Mol. Microbiol. 16:373-384.
    • (1995) Mol. Microbiol. , vol.16 , pp. 373-384
    • Kuzminov, A.1
  • 23
    • 0001313535 scopus 로고
    • The distribution of the numbers of mutants in bacterial populations
    • Lea, D. E., and C. A. Coulson. 1947. The distribution of the numbers of mutants in bacterial populations. J. Genet. 49:264-285.
    • (1947) J. Genet. , vol.49 , pp. 264-285
    • Lea, D.E.1    Coulson, C.A.2
  • 25
    • 0032493889 scopus 로고    scopus 로고
    • Saccharomyces Ku70, Mre11/Rad50, and RPA proteins regulate adaptation to G2/M arrest after DNA damage
    • Lee, S. E., J. K. Moore, A. Holmes, K. Umezu, R. Kolodner, and J. E. Haber. 1998. Saccharomyces Ku70, Mre11/Rad50, and RPA proteins regulate adaptation to G2/M arrest after DNA damage. Cell 94:399-409.
    • (1998) Cell , vol.94 , pp. 399-409
    • Lee, S.E.1    Moore, J.K.2    Holmes, A.3    Umezu, K.4    Kolodner, R.5    Haber, J.E.6
  • 26
    • 0029954821 scopus 로고    scopus 로고
    • Mutations in two Ku homologs define a DNA end-joining repair pathway in Saccharomyces cerevisiae
    • Milne, G. T., S. Jin, K. B. Shannon, and D. T. Weaver. 1996. Mutations in two Ku homologs define a DNA end-joining repair pathway in Saccharomyces cerevisiae. Mol. Cell. Biol. 16:4189-4198.
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 4189-4198
    • Milne, G.T.1    Jin, S.2    Shannon, K.B.3    Weaver, D.T.4
  • 27
    • 0029976325 scopus 로고    scopus 로고
    • Cell cycle and genetic requirements of two pathways of nonhomologous end-joining repair of double-strand breaks in Saccharomyces cerevisiae
    • Moore, J. K., and J. E. Haber. 1996. Cell cycle and genetic requirements of two pathways of nonhomologous end-joining repair of double-strand breaks in Saccharomyces cerevisiae. Mol. Cell. Biol. 16:2164-2173.
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 2164-2173
    • Moore, J.K.1    Haber, J.E.2
  • 28
    • 0032931844 scopus 로고    scopus 로고
    • The nuclease activity of mre11 is required for meiosis but not for mating-type switching, end joining, or telomere maintenance
    • Moreau, S., J. R. Ferguson, and L. S. Symington. 1999. The nuclease activity of mre11 is required for meiosis but not for mating-type switching, end joining, or telomere maintenance. Mol. Cell. Biol. 19:556-566.
    • (1999) Mol. Cell. Biol. , vol.19 , pp. 556-566
    • Moreau, S.1    Ferguson, J.R.2    Symington, L.S.3
  • 29
    • 0001281882 scopus 로고
    • Radiobiological and genetic studies on a polyploid series (haploid to hexaploid) of Saccharomyces cerevisiae
    • Mortimer, R. K. 1958. Radiobiological and genetic studies on a polyploid series (haploid to hexaploid) of Saccharomyces cerevisiae. Radiat. Res. 9:312-326.
    • (1958) Radiat. Res. , vol.9 , pp. 312-326
    • Mortimer, R.K.1
  • 30
    • 0032085295 scopus 로고    scopus 로고
    • The 3′ to 5′ exonuclease activity of Mre11 facilitates repair of DNA double-strand breaks
    • Paull, T. T., and M. Gellert. 1998. The 3′ to 5′ exonuclease activity of Mre11 facilitates repair of DNA double-strand breaks. Mol. Cell 1:969-979.
    • (1998) Mol. Cell , vol.1 , pp. 969-979
    • Paull, T.T.1    Gellert, M.2
  • 32
    • 0031171269 scopus 로고    scopus 로고
    • The RAD52 epistasis group in mammalian double strand break repair
    • Petrini, J. H. J., D. A. Bressan, and M. S. Yao. 1997. The RAD52 epistasis group in mammalian double strand break repair. Semin. Immunol. 9:181-188.
    • (1997) Semin. Immunol. , vol.9 , pp. 181-188
    • Petrini, J.H.J.1    Bressan, D.A.2    Yao, M.S.3
  • 33
    • 0017255643 scopus 로고
    • The repair of double-strand breaks in the nuclear DNA of Saccharomyces cerevisiae and its genetic control
    • Resnick, M. A., and P. Martin. 1976. The repair of double-strand breaks in the nuclear DNA of Saccharomyces cerevisiae and its genetic control. Mol. Gen. Genet. 143:119-129.
    • (1976) Mol. Gen. Genet. , vol.143 , pp. 119-129
    • Resnick, M.A.1    Martin, P.2
  • 34
    • 0019172203 scopus 로고
    • Genetic control of diploid recovery after γ-irradiation in the yeast Saccharomyces cerevisiae
    • Saeki, T., I. Machida, and S. Nakai. 1980. Genetic control of diploid recovery after γ-irradiation in the yeast Saccharomyces cerevisiae. Mutat. Res. 73:251-265.
    • (1980) Mutat. Res. , vol.73 , pp. 251-265
    • Saeki, T.1    Machida, I.2    Nakai, S.3
  • 35
    • 0024669291 scopus 로고
    • A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae
    • Sikorski, R. S., and P. Hieter. 1989. A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae. Genetics 122:19-27.
    • (1989) Genetics , vol.122 , pp. 19-27
    • Sikorski, R.S.1    Hieter, P.2
  • 36
    • 0020541955 scopus 로고
    • The double-strand break repair model for recombination
    • Szostak, J. W., T. L. Orr-Weaver, R. J. Rothstein, and F. W. Stahl. 1983. The double-strand break repair model for recombination. Cell 33:25-35.
    • (1983) Cell , vol.33 , pp. 25-35
    • Szostak, J.W.1    Orr-Weaver, T.L.2    Rothstein, R.J.3    Stahl, F.W.4
  • 37
    • 0032555480 scopus 로고    scopus 로고
    • Nuclease activities in a complex of human recombination and DNA repair factors Rad50, Mre11, and p95
    • Trujillo, K. M., S. S. Yuan, E. Y. Lee, and P. Sung. 1998. Nuclease activities in a complex of human recombination and DNA repair factors Rad50, Mre11, and p95. J. Biol. Chem. 273:21447-21450.
    • (1998) J. Biol. Chem. , vol.273 , pp. 21447-21450
    • Trujillo, K.M.1    Yuan, S.S.2    Lee, E.Y.3    Sung, P.4
  • 38
    • 0032567108 scopus 로고    scopus 로고
    • Complex formation and functional versatility of Mre11 of budding yeast in recombination
    • Usui, T., T. Ohta, H. Oshiumi, J. Tomizawa, H. Ogawa, and T. Ogawa. 1998. Complex formation and functional versatility of Mre11 of budding yeast in recombination. Cell 95:705-716.
    • (1998) Cell , vol.95 , pp. 705-716
    • Usui, T.1    Ohta, T.2    Oshiumi, H.3    Tomizawa, J.4    Ogawa, H.5    Ogawa, T.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.