Conditional deletion of Nbs1 in murine cells reveals its role in branching repair pathways of DNA double-strand breaks

EMBO Journal

Volumn 25, Issue 23, 2006, Pages 5527-5538

  Yang, Yun Gui ^a,c   Saidi, Amal ^b   Frappart, Pierre Olivier ^a,d   Min, Wookee ^b   Barrucand, Christelle ^a   Dumon Jones, Valérie ^a   Michelon, Jocelyne ^a   Herceg, Zdenko ^a   Wang, Zhao Qi ^a,b  

^a INTERNATIONAL AGENCY FOR RESEARCH ON CANCER   (France)

^b FRITZ LIPMANN INSTITUTE   (Germany)

^c IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

^d ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

Author keywords

DNA double strand break; Homology directed repair; NBS1; Nonhomologous end joining; Single stranded annealing

Indexed keywords

BRCA1 PROTEIN; CRE RECOMBINASE; DOUBLE STRANDED DNA; KU ANTIGEN; MRE11 PROTEIN; NIBRIN; RAD50 PROTEIN;

ARTICLE; CHROMATIN; COMPLEX FORMATION; DNA REPAIR; DNA SEQUENCE; DNA STRAND BREAKAGE; EMBRYO; EMBRYONIC STEM CELL; FIBROBLAST; GENE TARGETING; HOMOLOGOUS REPAIR; HOMOLOGY DIRECTED REPAIR; LOXP SITE; MOUSE; NON HOMOLOGOUS END JOINING; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN FUNCTION; SEQUENCE HOMOLOGY; SINGLE STRANDED ANNEALING PATHWAY;

ANIMALS; ANTIGENS, NUCLEAR; ATP-BINDING CASSETTE TRANSPORTERS; CELL CYCLE PROTEINS; CELL LINE; CELL PROLIFERATION; CHROMATIN; DNA BREAKS, DOUBLE-STRANDED; DNA REPAIR; DNA REPAIR ENZYMES; DNA, SINGLE-STRANDED; DNA-BINDING PROTEINS; EMBRYONIC STEM CELLS; FIBROBLASTS; GENE TARGETING; INTEGRASES; MICE; NUCLEAR PROTEINS; RAD51 RECOMBINASE; SEQUENCE DELETION;

MAMMALIA; MURINAE;

EID: 33751583362     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.1038/sj.emboj.7601411     Document Type: Article

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