메뉴 건너뛰기




Volumn 421, Issue 6926, 2003, Pages 952-956

MDC1 is required for the intra-S-phase DNA damage checkpoint

Author keywords

[No Author keywords available]

Indexed keywords

DEGRADATION; IONIZING RADIATION; PROTEINS; SYNTHESIS (CHEMICAL);

EID: 0037468169     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/nature01445     Document Type: Article
Times cited : (441)

References (30)
  • 1
    • 0036276388 scopus 로고    scopus 로고
    • The Mre11 complex: At the crossroads of DNA repair and checkpoint signalling
    • D'Amours, D. & Jackson, S. P. The Mre11 complex: at the crossroads of DNA repair and checkpoint signalling. Nature Rev. Mol. Cell Biol. 3, 317-327 (2002).
    • (2002) Nature Rev. Mol. Cell. Biol. , vol.3 , pp. 317-327
    • D'Amours, D.1    Jackson, S.P.2
  • 2
    • 0034106722 scopus 로고    scopus 로고
    • ATM-dependent phosphorylation of nibrin in response to radiation exposure
    • Gatei, M. et al. ATM-dependent phosphorylation of nibrin in response to radiation exposure. Nature Genet. 25, 115-119 (2000).
    • (2000) Nature Genet. , vol.25 , pp. 115-119
    • Gatei, M.1
  • 3
    • 0034611728 scopus 로고    scopus 로고
    • ATM phosphorylates p95/nbsl in an S-phase checkpoint pathway
    • Lim, D. S. et al. ATM phosphorylates p95/nbsl in an S-phase checkpoint pathway. Nature 404, 613-617 (2000).
    • (2000) Nature , vol.404 , pp. 613-617
    • Lim, D.S.1
  • 4
    • 0034713466 scopus 로고    scopus 로고
    • ATM phosphorylation of Nijmegen breakage syndrome protein is required in a DNA damage response
    • Wu, X. et al. ATM phosphorylation of Nijmegen breakage syndrome protein is required in a DNA damage response. Nature 405, 477-482 (2000).
    • (2000) Nature , vol.405 , pp. 477-482
    • Wu, X.1
  • 5
    • 0034713393 scopus 로고    scopus 로고
    • Functional link between ataxia-telangiectasia and Nijmegen breakage syndrome gene products
    • Zhao, S. et al. Functional link between ataxia-telangiectasia and Nijmegen breakage syndrome gene products. Nature 405, 473-477 (2000).
    • (2000) Nature , vol.405 , pp. 473-477
    • Zhao, S.1
  • 6
    • 0032076248 scopus 로고    scopus 로고
    • The hMre11/hRad50 protein complex and Nijmegen breakage syndrome: Linkage of double-strand break repair to the cellular DNA damage response
    • Carney, J. P. et al. The hMre11/hRad50 protein complex and Nijmegen breakage syndrome: Linkage of double-strand break repair to the cellular DNA damage response. Cell 93, 477-486 (1998).
    • (1998) Cell , vol.93 , pp. 477-486
    • Carney, J.P.1
  • 7
    • 17344372572 scopus 로고    scopus 로고
    • Positional cloning of the gene for Nijmegen breakage syndrome
    • Matsuura, S. et al. Positional cloning of the gene for Nijmegen breakage syndrome. Nature Genet. 19, 179-181 (1998).
    • (1998) Nature Genet. , vol.19 , pp. 179-181
    • Matsuura, S.1
  • 8
    • 0033544724 scopus 로고    scopus 로고
    • The DNA double-strand break repair gene hMRE11 is mutated in individuals with an ataxia-telangiectasia-like disorder
    • Stewart, G. S. et al. The DNA double-strand break repair gene hMRE11 is mutated in individuals with an ataxia-telangiectasia-like disorder. Cell 99, 577-587 (1999).
    • (1999) Cell , vol.99 , pp. 577-587
    • Stewart, G.S.1
  • 9
    • 0029057336 scopus 로고
    • A single ataxia telangiectasia gene with a product similar to P1-3 kinase
    • Savitsky, K. et al. A single ataxia telangiectasia gene with a product similar to P1-3 kinase. Science 268, 1749-1753 (1995).
    • (1995) Science , vol.268 , pp. 1749-1753
    • Savitsky, K.1
  • 10
    • 0032076190 scopus 로고    scopus 로고
    • Nibrin, a novel DNA double-strand break repair protein, is mutated in Nijmegen breakage syndrome
    • Varon, R. et al. Nibrin, a novel DNA double-strand break repair protein, is mutated in Nijmegen breakage syndrome. Cell 93, 467-476 (1998).
    • (1998) Cell , vol.93 , pp. 467-476
    • Varon, R.1
  • 11
    • 0033773501 scopus 로고    scopus 로고
    • Closing the gaps among a web of DNA repair disorders
    • Michelson, R. J. & Weinert, T. Closing the gaps among a web of DNA repair disorders. BioEssays 22, 966-969 (2000).
    • (2000) BioEssays , vol.22 , pp. 966-969
    • Michelson, R.J.1    Weinert, T.2
  • 12
    • 0031466618 scopus 로고    scopus 로고
    • Ataxia-telangiectasia and the Nijmegen breakage syndrome: Related disorders but genes apart
    • Shiloh, Y. Ataxia-telangiectasia and the Nijmegen breakage syndrome: Related disorders but genes apart. Annu. Rev. Genet. 31, 635-662 (1997).
    • (1997) Annu. Rev. Genet. , vol.31 , pp. 635-662
    • Shiloh, Y.1
  • 13
    • 0036510055 scopus 로고    scopus 로고
    • The DNA damage-dependent intra-S phase checkpoint is regulated by parallel pathways
    • Falck, J., Petrini, J. H., Williams, B. R., Lukas, J. & Bartek, J. The DNA damage-dependent intra-S phase checkpoint is regulated by parallel pathways. Nature Genet. 30, 290-294 (2002).
    • (2002) Nature Genet. , vol.30 , pp. 290-294
    • Falck, J.1    Petrini, J.H.2    Williams, B.R.3    Lukas, J.4    Bartek, J.5
  • 14
    • 0030605415 scopus 로고    scopus 로고
    • Prediction of the coding sequences of unidentified human genes. V. The coding sequences of 40 new genes (KIAA0161-KIAA0200) deduced by analysis of cDNA clones from human cell line KG-1
    • Nagase, T., Seki, N., Ishikawa, K., Tanaka, A. & Nomura, N. Prediction of the coding sequences of unidentified human genes. V. The coding sequences of 40 new genes (KIAA0161-KIAA0200) deduced by analysis of cDNA clones from human cell line KG-1. DNA Res. 3, 17-24 (1996).
    • (1996) DNA Res. , vol.3 , pp. 17-24
    • Nagase, T.1    Seki, N.2    Ishikawa, K.3    Tanaka, A.4    Nomura, N.5
  • 16
    • 0031046294 scopus 로고    scopus 로고
    • A superfamily of conserved domains in DNA damage-responsive cell cycle checkpoint proteins
    • Bork, P. et al. A superfamily of conserved domains in DNA damage-responsive cell cycle checkpoint proteins. FASEB J. 11, 68-76 (1997).
    • (1997) FASEB J. , vol.11 , pp. 68-76
    • Bork, P.1
  • 17
    • 0035449355 scopus 로고    scopus 로고
    • Cell cycle checkpoint signaling through the ATM and ATR kinases
    • Abraham, R. T. Cell cycle checkpoint signaling through the ATM and ATR kinases. Genes Dev. 15, 2177-2196 (2001).
    • (2001) Genes Dev. , vol.15 , pp. 2177-2196
    • Abraham, R.T.1
  • 18
    • 0030764691 scopus 로고    scopus 로고
    • hMre11 and hRad50 nuclear foci are induced during the normal cellular response to DNA double-strand breaks
    • Maser, R. S., Monsen, K. J., Nelms, B. E. & Petrini, J. H. hMre11 and hRad50 nuclear foci are induced during the normal cellular response to DNA double-strand breaks. Mol. Cell. Biol. 17, 6087-6096 (1997).
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 6087-6096
    • Maser, R.S.1    Monsen, K.J.2    Nelms, B.E.3    Petrini, J.H.4
  • 19
    • 0034739853 scopus 로고    scopus 로고
    • p53 binding protein 1 (53BP1) is an early participant in the cellular response to DNA double-strand breaks
    • Schultz, L. B., Chehab, N. H., Malikzay, A. & Halazonetis, T. D. p53 binding protein 1 (53BP1) is an early participant in the cellular response to DNA double-strand breaks. J. Cell Biol. 151, 1381-1390 (2000).
    • (2000) J. Cell Biol. , vol.151 , pp. 1381-1390
    • Schultz, L.B.1    Chehab, N.H.2    Malikzay, A.3    Halazonetis, T.D.4
  • 20
    • 0343280013 scopus 로고    scopus 로고
    • A critical role for histone H2AX in recruitment of repair factors to nuclear foci after DNA damage
    • Paull, T. T. et al. A critical role for histone H2AX in recruitment of repair factors to nuclear foci after DNA damage. Curr. Biol. 10, 886-895 (2000).
    • (2000) Curr. Biol. , vol.10 , pp. 886-895
    • Paull, T.T.1
  • 21
    • 0032861343 scopus 로고    scopus 로고
    • Megabase chromatin domains involved in DNA double-strand breaks in vivo
    • Rogakou, E. P., Boon, C., Redon, C. & Bonner, W. M. Megabase chromatin domains involved in DNA double-strand breaks in vivo. J. Cell Biol. 146, 905-916 (1999).
    • (1999) J. Cell Biol. , vol.146 , pp. 905-916
    • Rogakou, E.P.1    Boon, C.2    Redon, C.3    Bonner, W.M.4
  • 22
    • 0035834693 scopus 로고    scopus 로고
    • ATM phosphorylates histone H2AX in response to DNA double-strand breaks
    • Burma, S., Chen, B. P., Murphy, M., Kurimasa, A. & Chen, D. J. ATM phosphorylates histone H2AX in response to DNA double-strand breaks. J. Biol. Chem. 276, 42462-42467 (2001).
    • (2001) J. Biol. Chem. , vol.276 , pp. 42462-42467
    • Burma, S.1    Chen, B.P.2    Murphy, M.3    Kurimasa, A.4    Chen, D.J.5
  • 23
    • 0032189483 scopus 로고    scopus 로고
    • Inhibition of phosphoinositide 3-kinase related kinases by the radiosensitizing agent wortmannin
    • Sarkaria, J. N. et al. Inhibition of phosphoinositide 3-kinase related kinases by the radiosensitizing agent wortmannin. Cancer Res. 58, 4375-4382 (1998).
    • (1998) Cancer Res. , vol.58 , pp. 4375-4382
    • Sarkaria, J.N.1
  • 24
    • 0035942736 scopus 로고    scopus 로고
    • Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells
    • Elbashir, S. M. et al. Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells. Nature 411, 494-498 (2001).
    • (2001) Nature , vol.411 , pp. 494-498
    • Elbashir, S.M.1
  • 25
    • 0036285705 scopus 로고    scopus 로고
    • Structural and functional versatility of the FHA domain in DNA-damage signaling by the tumour suppressor kinase Chk2
    • Li, J. et al. Structural and functional versatility of the FHA domain in DNA-damage signaling by the tumour suppressor kinase Chk2. Mol. Cell 9, 1045-1054 (2002).
    • (2002) Mol. Cell , vol.9 , pp. 1045-1054
    • Li, J.1
  • 26
    • 0035848819 scopus 로고    scopus 로고
    • The ATM-Chk2-Cdc25A checkpoint pathway guards against radioresistant DNA synthesis
    • Falck, J., Mailand, N., Syljuasen, R. G., Bartek, J. & Lukas, J. The ATM-Chk2-Cdc25A checkpoint pathway guards against radioresistant DNA synthesis. Nature 410, 842-847 (2001).
    • (2001) Nature , vol.410 , pp. 842-847
    • Falck, J.1    Mailand, N.2    Syljuasen, R.G.3    Bartek, J.4    Lukas, J.5
  • 27
    • 0036500690 scopus 로고    scopus 로고
    • SMC1 is a downstream effector in the ATM/NBS1 branch of the human S-phase checkpoint
    • Yazdi, P. T. et al. SMC1 is a downstream effector in the ATM/NBS1 branch of the human S-phase checkpoint. Genes Dev. 16, 571-582 (2002).
    • (2002) Genes Dev. , vol.16 , pp. 571-582
    • Yazdi, P.T.1
  • 28
    • 0036500555 scopus 로고    scopus 로고
    • Involvement of the cohesin protein, Smc1, in Atm-dependent and independent responses to DNA damage
    • Kim, S. T., Xu, B. & Kastan, M. B. Involvement of the cohesin protein, Smc1, in Atm-dependent and independent responses to DNA damage. Genes Dev. 16, 560-570 (2002).
    • (2002) Genes Dev. , vol.16 , pp. 560-570
    • Kim, S.T.1    Xu, B.2    Kastan, M.B.3
  • 29
    • 0034903925 scopus 로고    scopus 로고
    • Mre11 complex and DNA replication: Linkage to E2F and sites of DNA synthesis
    • Maser, R. S. et al. Mre11 complex and DNA replication: Linkage to E2F and sites of DNA synthesis. Mol. Cell Biol. 21, 6006-6016 (2001).
    • (2001) Mol. Cell Biol. , vol.21 , pp. 6006-6016
    • Maser, R.S.1
  • 30
    • 0034473861 scopus 로고    scopus 로고
    • NFBD1/KIAA0170 is a novel nuclear transcriptional transactivator with BRCT domain
    • Ozaki, T. et al. NFBD1/KIAA0170 is a novel nuclear transcriptional transactivator with BRCT domain. DNA Cell Biol. 19, 475-485 (2000).
    • (2000) DNA Cell Biol. , vol.19 , pp. 475-485
    • Ozaki, T.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.