Selection of targets for drug development against protozoan parasites

Current Drug Targets

Volumn 10, Issue 3, 2009, Pages 193-201

  de Azevedo Jr , Walter Filgueira ^a,d   Soares, Milena Botelho Pereira ^b,c  

^a PONTIFICAL CATHOLIC UNIVERSITY OF RIO GRANDE DO SUL   (Brazil)

^b INSTITUTO OSWALDO CRUZ   (Brazil)

^c HOSPITAL SÃO RAFAEL   (Brazil)

^d NONE   (Brazil)

Author keywords

Drug design; Molecular targets; Parasites; Virtual screening

Indexed keywords

6 FLUOROSHIKIMIC ACID; ANTIPARASITIC AGENT; CHORISMATE SYNTHASE; CHORISMIC ACID; CYCLIN DEPENDENT KINASE 1; CYCLIN DEPENDENT KINASE 5; CYCLIN DEPENDENT KINASE 6; PURINE NUCLEOSIDE PHOSPHORYLASE; PURINE NUCLEOSIDE PHOSPHORYLASE INHIBITOR; ROSCOVITINE; SHIKIMIC ACID; UNCLASSIFIED DRUG;

BIOINFORMATICS; DRUG MECHANISM; DRUG SCREENING; DRUG TARGETING; ENZYME ACTIVITY; ENZYME METABOLISM; GENE SEQUENCE; GENOME ANALYSIS; GROWTH INHIBITION; HUMAN; LEISHMANIA MAJOR; MATHEMATICAL COMPUTING; NONHUMAN; PARASITOSIS; PLASMODIUM FALCIPARUM; PRODUCT DEVELOPMENT; PROTEIN ANALYSIS; PROTEIN DETERMINATION; PROTEIN STRUCTURE; PROTEIN TARGETING; PROTOZOON; REVIEW; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY; STRUCTURE ACTIVITY RELATION; TRYPANOSOMA BRUCEI; TRYPANOSOMA CRUZI; VIRTUAL REALITY;

ANIMALS; ANTIPROTOZOAL AGENTS; DRUG DELIVERY SYSTEMS; DRUG DESIGN; GENOME, PROTOZOAN; HUMANS; MOLECULAR SEQUENCE DATA; PROTEIN KINASES; PROTOZOAN INFECTIONS; PURINE-NUCLEOSIDE PHOSPHORYLASE; SHIKIMIC ACID;

EID: 65549153047     PISSN: 13894501     EISSN: None     Source Type: Journal    
DOI: 10.2174/138945009787581186     Document Type: Review

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