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Journal of Biological Chemistry

Volumn 277, Issue 5, 2002, Pages 3219-3225

Transition state analogue inhibitors of purine nucleoside phosphorylase from Plasmodium falciparum

(6) Kicska, Gregory A a,d Tyler, Peter C a,c Evans, Gary B a Furneaux, Richard H c Kim, Kami a,b Schramm, Vern L a,c

a Departments of Biochemistry (United States)

b Division of Infectious Diseases (United States)

c ALBERT EINSTEIN COLLEGE OF MEDICINE (United States)

d CALLAGHAN INNOVATION (New Zealand)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; CELL CULTURE; DISSOCIATION; ENZYMES; ESCHERICHIA COLI;

BINDING INHIBITORS;

BIOCHEMISTRY;

DEOXYGUANOSINE; GUANOSINE; IMMUCILLIN; IMMUCILLIN A; IMMUCILLIN G; IMMUCILLIN H; INOSINE; PURINE NUCLEOSIDE PHOSPHORYLASE; PURINE NUCLEOSIDE PHOSPHORYLASE INHIBITOR; RECOMBINANT ENZYME; UNCLASSIFIED DRUG; URIDINE PHOSPHORYLASE;

AMINO ACID SEQUENCE; ANTIMICROBIAL ACTIVITY; ARTICLE; BINDING AFFINITY; DRUG STRUCTURE; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME INHIBITION; ENZYME SPECIFICITY; GENE OVEREXPRESSION; GENETIC DISTANCE; GENOME; INHIBITION KINETICS; MOLECULAR CLONING; NONHUMAN; NUCLEOTIDE SEQUENCE; OPEN READING FRAME; PHYLOGENY; PLASMODIUM FALCIPARUM; PRIORITY JOURNAL; PURINE METABOLISM; SEQUENCE HOMOLOGY;

AMINO ACID SEQUENCE; ANIMALS; CLONING, MOLECULAR; CONSENSUS SEQUENCE; ENZYME INHIBITORS; ERYTHROCYTES; ESCHERICHIA COLI; GENOME, PROTOZOAN; HUMANS; KINETICS; MAMMALS; MOLECULAR SEQUENCE DATA; OPEN READING FRAMES; PLASMODIUM FALCIPARUM; PURINE-NUCLEOSIDE PHOSPHORYLASE; RECOMBINANT PROTEINS; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY, AMINO ACID; SUBSTRATE SPECIFICITY;

ESCHERICHIA COLI; MAMMALIA; PLASMODIUM FALCIPARUM;

EID: 0036479331 PISSN: 00219258 EISSN: None Source Type: Journal
DOI: 10.1074/jbc.M105905200 Document Type: Article

Times cited : (105)

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