Crystal structure of human purine nucleoside phosphorylase at 2.3 Å resolution

Biochemical and Biophysical Research Communications

Volumn 308, Issue 3, 2003, Pages 545-552

  De Azevedo Jr , Walter Filgueira ^a,b   Canduri, Fernanda ^a,b   Dos Santos, Denis Marangoni ^a,b   Silva, Rafael Guimarães ^c   De Oliveira, Jaim Simões ^c   De Carvalho, Luiz Pedro Sório ^c   Basso, Luiz Augusto ^c   Mendes, Maria Anita ^a,b   Palma, Mário Sérgio ^a,b   Santos, Diógenes Santiago ^c,d  

^a SÃO PAULO STATE UNIVERSITY UNESP   (Brazil)

^b INSTITUTO BUTANTAN   (Brazil)

^c FEDERAL UNIVERSITY OF RIO GRANDE DO SUL   (Brazil)

^d PONTIFICAL CATHOLIC UNIVERSITY OF RIO GRANDE DO SUL   (Brazil)

Author keywords

Drug design; PNP; Structure; Synchrotron radiation

Indexed keywords

DEOXYGUANOSINE; PURINE NUCLEOSIDE PHOSPHORYLASE INHIBITOR;

ARTICLE; CRYSTAL STRUCTURE; DRUG STRUCTURE; ENZYME ACTIVE SITE; ENZYME DEGRADATION; ENZYME PHOSPHORYLATION; ENZYME STRUCTURE; ENZYME SUBSTRATE COMPLEX; GENETIC DISORDER; IMMUNE RESPONSE; IMMUNOSUPPRESSIVE TREATMENT; PRIORITY JOURNAL; PROTEIN TARGETING; T LYMPHOCYTE;

EID: 0042490762     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-291X(03)01431-1     Document Type: Article

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