Significance of water molecules in the inhibition of cylin-dependent kinase 2 and 5 complexes

Journal of Chemical Information and Modeling

Volumn 47, Issue 5, 2007, Pages 1877-1885

  Zhang, B ^a,b   Tan, V B C ^b   Lim, K M ^b   Tay, T E ^b  

^a ZHEJIANG UNIVERSITY   (China)

^b NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEXATION; DISEASES; ENZYME INHIBITION; HYDROGEN BONDS; MOLECULAR DYNAMICS; TUMORS; X RAY CRYSTALLOGRAPHY;

BINDING CONFORMATIONS; BINDING PATTERNS; OSCOVITINE;

WATER;

FRAGILE X MENTAL RETARDATION PROTEIN; OXAZOLE DERIVATIVE; PYRIMIDINE DERIVATIVE;

ALGORITHM; ARTICLE; ARTIFACT; CELL; CHEMISTRY; CLUSTER ANALYSIS; COMBINATORIAL CHEMISTRY; COMPUTER; DATA BASE; DRUG DESIGN; DRUG EFFECT; DRUG POTENTIATION; METABOLISM; STRUCTURE ACTIVITY RELATION;

ALGORITHMS; ARTIFACTS; CELLS; CLUSTER ANALYSIS; COMBINATORIAL CHEMISTRY TECHNIQUES; COMPUTERS; DATABASES AS TOPIC; DRUG DESIGN; FRAGILE X MENTAL RETARDATION PROTEIN; OXAZOLES; PYRIMIDINES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 35248833733     PISSN: 15499596     EISSN: 1549960X     Source Type: Journal    
DOI: 10.1021/ci700137c     Document Type: Article

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