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Volumn , Issue , 2008, Pages 87-118

Viral Quasispecies: Dynamics, Interactions, and Pathogenesis*

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EID: 47649124088     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1016/B978-0-12-374153-0.00004-7     Document Type: Chapter
Times cited : (30)

References (250)
  • 1
    • 30844446303 scopus 로고    scopus 로고
    • Long-term transmission of defective RNA viruses in humans and Aedes mosquitoes
    • J. Aaskov, K. Buzacott, H.M. Thu, K. Lowry and E.C. Holmes (2006) Long-term transmission of defective RNA viruses in humans and Aedes mosquitoes. Science 311 236-238.
    • (2006) Science , vol.311 , pp. 236-238
    • Aaskov, J.1    Buzacott, K.2    Thu, H.M.3    Lowry, K.4    Holmes, E.C.5
  • 2
    • 0038722333 scopus 로고    scopus 로고
    • Curing of foot-and-mouth disease virus from persistently infected cells by ribavirin involves enhanced mutagenesis
    • A. Airaksinen, N. Pariente, L. Menendez-Arias and E. Domingo (2003) Curing of foot-and-mouth disease virus from persistently infected cells by ribavirin involves enhanced mutagenesis. Virology 311 339-349.
    • (2003) Virology , vol.311 , pp. 339-349
    • Airaksinen, A.1    Pariente, N.2    Menendez-Arias, L.3    Domingo, E.4
  • 3
    • 33748642580 scopus 로고    scopus 로고
    • Analysis of genetic bottlenecks during horizontal transmission of Cucumber mosaic virus
    • A. Ali, H. Li, W.L. Schneider, D.J. Sherman, S. Gray, D. Smith and M.J. Roossinck (2006) Analysis of genetic bottlenecks during horizontal transmission of Cucumber mosaic virus. J. Virol. 80 8345-8350.
    • (2006) J. Virol. , vol.80 , pp. 8345-8350
    • Ali, A.1    Li, H.2    Schneider, W.L.3    Sherman, D.J.4    Gray, S.5    Smith, D.6    Roossinck, M.J.7
  • 5
    • 0033863784 scopus 로고    scopus 로고
    • Mutants of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase resistant to nonnucleoside reverse transcriptase inhibitors demonstrate altered rates of RNase H cleavage that correlate with HIV-1 replication fitness in cell culture
    • R.H. Archer, C. Dykes, P. Gerondelis, A. Lloyd, P. Fay, R.C. Reichman, R.A. Bambara and L.M. Demeter (2000) Mutants of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase resistant to nonnucleoside reverse transcriptase inhibitors demonstrate altered rates of RNase H cleavage that correlate with HIV-1 replication fitness in cell culture. J. Virol. 74 8390-8401.
    • (2000) J. Virol. , vol.74 , pp. 8390-8401
    • Archer, R.H.1    Dykes, C.2    Gerondelis, P.3    Lloyd, A.4    Fay, P.5    Reichman, R.C.6    Bambara, R.A.7    Demeter, L.M.8
  • 6
    • 2342565012 scopus 로고    scopus 로고
    • Fitness increase of memory genomes in a viral quasispecies
    • A. Arias, C.M. Ruiz-Jarabo, C. Escarmis and E. Domingo (2004) Fitness increase of memory genomes in a viral quasispecies. J. Mol. Biol. 339 405-412.
    • (2004) J. Mol. Biol. , vol.339 , pp. 405-412
    • Arias, A.1    Ruiz-Jarabo, C.M.2    Escarmis, C.3    Domingo, E.4
  • 7
    • 27144462037 scopus 로고    scopus 로고
    • Mutant viral polymerase in the transition of virus to error catastrophe identifies a critical site for RNA binding
    • A. Arias, R. Agudo, C. Ferrer-Orta, R. Perez-Luque, A. Airaksinen, E. Brocchi, et al. (2005) Mutant viral polymerase in the transition of virus to error catastrophe identifies a critical site for RNA binding. J. Mol. Biol. 353 1021-1032.
    • (2005) J. Mol. Biol. , vol.353 , pp. 1021-1032
    • Arias, A.1    Agudo, R.2    Ferrer-Orta, C.3    Perez-Luque, R.4    Airaksinen, A.5    Brocchi, E.6
  • 8
    • 27144455019 scopus 로고    scopus 로고
    • Replicative fitness of historical and recent HIV-1 isolates suggests HIV-1 attenuation over time
    • K.K. Arien, R.M. Troyer, Y. Gali, R.L. Colebunders, E.J. Arts and G. Vanham (2005) Replicative fitness of historical and recent HIV-1 isolates suggests HIV-1 attenuation over time. AIDS 19 1555-1564.
    • (2005) AIDS , vol.19 , pp. 1555-1564
    • Arien, K.K.1    Troyer, R.M.2    Gali, Y.3    Colebunders, R.L.4    Arts, E.J.5    Vanham, G.6
  • 9
    • 21844431621 scopus 로고    scopus 로고
    • Remote site control of an active site fidelity checkpoint in a viral RNA-dependent RNA polymerase
    • J.J. Arnold, M. Vignuzzi, J.K. Stone, R. Andino and C.E. Cameron (2005) Remote site control of an active site fidelity checkpoint in a viral RNA-dependent RNA polymerase. J. Biol. Chem. 280 25706-25716.
    • (2005) J. Biol. Chem. , vol.280 , pp. 25706-25716
    • Arnold, J.J.1    Vignuzzi, M.2    Stone, J.K.3    Andino, R.4    Cameron, C.E.5
  • 12
    • 0029757751 scopus 로고    scopus 로고
    • Reduced replication of 3TC-resistant HIV-1 variants in primary cells due to a processivity defect of the reverse transcriptase enzyme
    • N.K. Back, M. Nijhuis, W. Keulen, C.A. Boucher, B.O. Oude Essink, A.B. van Kuilenburg, et al. (1996) Reduced replication of 3TC-resistant HIV-1 variants in primary cells due to a processivity defect of the reverse transcriptase enzyme. EMBO J. 15 4040-4049.
    • (1996) EMBO J. , vol.15 , pp. 4040-4049
    • Back, N.K.1    Nijhuis, M.2    Keulen, W.3    Boucher, C.A.4    Oude Essink, B.O.5    van Kuilenburg, A.B.6
  • 13
    • 0017038871 scopus 로고
    • The proportion of revertant and mutant phage in a growing population, as a function of mutation and growth rate
    • E. Batschelet, E. Domingo and C. Weissmann (1976) The proportion of revertant and mutant phage in a growing population, as a function of mutation and growth rate. Gene 1 27-32.
    • (1976) Gene , vol.1 , pp. 27-32
    • Batschelet, E.1    Domingo, E.2    Weissmann, C.3
  • 14
    • 0002076195 scopus 로고
    • The fidelity of retroviral reverse transcriptases
    • A.M. Skalka, S.P. Goff (Eds), New York: Cold Spring Harbor Laboratory Press
    • K. Bebenek and T.A. Kunkel (1993) The fidelity of retroviral reverse transcriptases. A.M. Skalka, S.P. Goff (Eds) Reverse Transcriptase New York: Cold Spring Harbor Laboratory Press 85-102.
    • (1993) Reverse Transcriptase , pp. 85-102
    • Bebenek, K.1    Kunkel, T.A.2
  • 15
    • 34249277103 scopus 로고    scopus 로고
    • The advantage of the high genetic diversity in RNA viruses
    • C.K. Biebricher and E. Domingo (2007) The advantage of the high genetic diversity in RNA viruses. Future Virol. 2 35-38.
    • (2007) Future Virol. , vol.2 , pp. 35-38
    • Biebricher, C.K.1    Domingo, E.2
  • 16
    • 11844274684 scopus 로고    scopus 로고
    • The error threshold
    • C.K. Biebricher and M. Eigen (2005) The error threshold. Virus Res. 107 117-127.
    • (2005) Virus Res. , vol.107 , pp. 117-127
    • Biebricher, C.K.1    Eigen, M.2
  • 17
    • 0019231684 scopus 로고
    • A theory of modular evolution for bacteriophages
    • D. Botstein (1980) A theory of modular evolution for bacteriophages. Ann. NY Acad. Sci. 354 484-491.
    • (1980) Ann. NY Acad. Sci. , vol.354 , pp. 484-491
    • Botstein, D.1
  • 18
    • 0033971425 scopus 로고    scopus 로고
    • Dynamics of dominance of a dipeptide insertion in reverse transcriptase of HIV-1 from patients subjected to prolonged therapy
    • C. Briones, A. Mas, G. Gomez-Mariano, C. Altisent, L. Menendez-Arias, V. Soriano and E. Domingo (2000) Dynamics of dominance of a dipeptide insertion in reverse transcriptase of HIV-1 from patients subjected to prolonged therapy. Virus Res. 66 13-26.
    • (2000) Virus Res. , vol.66 , pp. 13-26
    • Briones, C.1    Mas, A.2    Gomez-Mariano, G.3    Altisent, C.4    Menendez-Arias, L.5    Soriano, V.6    Domingo, E.7
  • 19
    • 0038499539 scopus 로고    scopus 로고
    • Memory in retroviral quasispecies: experimental evidence and theoretical model for human immunodeficiency virus
    • C. Briones, E. Domingo and C. Molina-París (2003) Memory in retroviral quasispecies: experimental evidence and theoretical model for human immunodeficiency virus. J. Mol. Biol. 331 213-229.
    • (2003) J. Mol. Biol. , vol.331 , pp. 213-229
    • Briones, C.1    Domingo, E.2    Molina-París, C.3
  • 20
    • 33751099319 scopus 로고    scopus 로고
    • Minority memory genomes can influence the evolution of HIV-1 quasispecies in vivo
    • C. Briones, A. de Vicente, C. Molina-Paris and E. Domingo (2006) Minority memory genomes can influence the evolution of HIV-1 quasispecies in vivo. Gene 384 129-138.
    • (2006) Gene , vol.384 , pp. 129-138
    • Briones, C.1    de Vicente, A.2    Molina-Paris, C.3    Domingo, E.4
  • 22
    • 0036381110 scopus 로고    scopus 로고
    • HIV-1 infection and low steady state viral loads
    • D.S. Callaway and A.S. Perelson (2002) HIV-1 infection and low steady state viral loads. Bull. Math. Biol. 64 29-64.
    • (2002) Bull. Math. Biol. , vol.64 , pp. 29-64
    • Callaway, D.S.1    Perelson, A.S.2
  • 23
    • 0031824587 scopus 로고    scopus 로고
    • In vivo analysis of the stability and fitness of variants recovered from foot-and-mouth disease virus quasispecies
    • C. Carrillo, M. Borca, D.M. Moore, D.O. Morgan and F. Sobrino (1998) In vivo analysis of the stability and fitness of variants recovered from foot-and-mouth disease virus quasispecies. J. Gen. Virol. 79 1699-1706.
    • (1998) J. Gen. Virol. , vol.79 , pp. 1699-1706
    • Carrillo, C.1    Borca, M.2    Moore, D.M.3    Morgan, D.O.4    Sobrino, F.5
  • 24
    • 33751552155 scopus 로고    scopus 로고
    • Mutational patterns associated with the 69 insertion complex in multi-drug-resistant HIV-1 reverse transcriptase that confer increased excision activity and high-level resistance to zidovudine
    • C.E. Cases-Gonzalez, S. Franco, M.A. Martinez and L. Menendez-Arias (2007) Mutational patterns associated with the 69 insertion complex in multi-drug-resistant HIV-1 reverse transcriptase that confer increased excision activity and high-level resistance to zidovudine. J. Mol. Biol. 365 298-309.
    • (2007) J. Mol. Biol. , vol.365 , pp. 298-309
    • Cases-Gonzalez, C.E.1    Franco, S.2    Martinez, M.A.3    Menendez-Arias, L.4
  • 25
    • 33751401848 scopus 로고    scopus 로고
    • Cell-specific adaptation of two flaviviruses following serial passage in mosquito cell culture
    • A.T. Ciota, A.O. Lovelace, K.A. Ngo, A.N. Le, J.G. Maffei, M.A. Franke, et al. (2007) Cell-specific adaptation of two flaviviruses following serial passage in mosquito cell culture. Virology 357 165-174.
    • (2007) Virology , vol.357 , pp. 165-174
    • Ciota, A.T.1    Lovelace, A.O.2    Ngo, K.A.3    Le, A.N.4    Maffei, J.G.5    Franke, M.A.6
  • 26
    • 33646749536 scopus 로고    scopus 로고
    • Mutations in retroviral genes associated with drug resistance
    • T. Leitner, B. Foley, B. Hahn, P. Marx, F. McCutchan, J. Mellors, S. Wolinsky, B. Korber (Eds), Los Alamos, NM: Theoretical Biology and Biophysics Group, Los Alamos National Laboratory
    • S.A. Clark, C. Calef and J.W. Mellors (2005) Mutations in retroviral genes associated with drug resistance. T. Leitner, B. Foley, B. Hahn, P. Marx, F. McCutchan, J. Mellors, S. Wolinsky, B. Korber (Eds) HIV Sequence Compendium 2005 Los Alamos, NM: Theoretical Biology and Biophysics Group, Los Alamos National Laboratory 80-174.
    • (2005) HIV Sequence Compendium 2005 , pp. 80-174
    • Clark, S.A.1    Calef, C.2    Mellors, J.W.3
  • 27
    • 0027509085 scopus 로고
    • Genetic bottlenecks and population passages cause profound fitness differences in RNA viruses
    • D.K. Clarke, E.A. Duarte, A. Moya, S.F. Elena, E. Domingo and J. Holland (1993) Genetic bottlenecks and population passages cause profound fitness differences in RNA viruses. J. Virol. 67 222-228.
    • (1993) J. Virol. , vol.67 , pp. 222-228
    • Clarke, D.K.1    Duarte, E.A.2    Moya, A.3    Elena, S.F.4    Domingo, E.5    Holland, J.6
  • 31
    • 2442657656 scopus 로고    scopus 로고
    • Identification of I50L as the signature atazanavir (ATV)-resistance mutation in treatment-naive HIV-1-infected patients receiving ATV-containing regimens
    • R. Colonno, R. Rose, C. McLaren, A. Thiry, N. Parkin and J. Friborg (2004) Identification of I50L as the signature atazanavir (ATV)-resistance mutation in treatment-naive HIV-1-infected patients receiving ATV-containing regimens. J. Infect. Dis. 189 1802-1810.
    • (2004) J. Infect. Dis. , vol.189 , pp. 1802-1810
    • Colonno, R.1    Rose, R.2    McLaren, C.3    Thiry, A.4    Parkin, N.5    Friborg, J.6
  • 32
  • 34
    • 0035811016 scopus 로고    scopus 로고
    • RNA virus error catastrophe: direct molecular test by using ribavirin
    • S. Crotty, C.E. Cameron and R. Andino (2001) RNA virus error catastrophe: direct molecular test by using ribavirin. Proc. Natl Acad. Sci. USA 98 6895-6900.
    • (2001) Proc. Natl Acad. Sci. USA , vol.98 , pp. 6895-6900
    • Crotty, S.1    Cameron, C.E.2    Andino, R.3
  • 35
    • 22844440540 scopus 로고    scopus 로고
    • Trans-dominant inhibition of RNA viral replication can slow growth of drug-resistant viruses
    • S. Crowder and K. Kirkegaard (2005) Trans-dominant inhibition of RNA viral replication can slow growth of drug-resistant viruses. Nat. Genet. 37 701-709.
    • (2005) Nat. Genet. , vol.37 , pp. 701-709
    • Crowder, S.1    Kirkegaard, K.2
  • 36
    • 0025244957 scopus 로고
    • Fitness of RNA virus decreased by Muller's ratchet
    • L. Chao (1990) Fitness of RNA virus decreased by Muller's ratchet. Nature 348 454-455.
    • (1990) Nature , vol.348 , pp. 454-455
    • Chao, L.1
  • 37
    • 0030245788 scopus 로고    scopus 로고
    • Long-term, large-population passage of aphthovirus can generate and amplify defective noninterfering particles deleted in the leader protease gene
    • N. Charpentier, M. Davila, E. Domingo and C. Escarmis (1996) Long-term, large-population passage of aphthovirus can generate and amplify defective noninterfering particles deleted in the leader protease gene. Virology 223 10-18.
    • (1996) Virology , vol.223 , pp. 10-18
    • Charpentier, N.1    Davila, M.2    Domingo, E.3    Escarmis, C.4
  • 39
    • 0026025541 scopus 로고
    • Correlation between amount of virus with altered nucleotide sequence and the monkey test for acceptability of oral poliovirus vaccine
    • K.M. Chumakov, L.B. Powers, K.E. Noonan, I.B. Roninson and I.S. Levenbook (1991) Correlation between amount of virus with altered nucleotide sequence and the monkey test for acceptability of oral poliovirus vaccine. Proc. Natl Acad. Sci. USA 88 199-203.
    • (1991) Proc. Natl Acad. Sci. USA , vol.88 , pp. 199-203
    • Chumakov, K.M.1    Powers, L.B.2    Noonan, K.E.3    Roninson, I.B.4    Levenbook, I.S.5
  • 40
    • 34447093479 scopus 로고    scopus 로고
    • Triphasic decline of hepatitis C virus RNA during antiviral therapy
    • H. Dahari, R.M. Ribeiro and A.S. Perelson (2007) Triphasic decline of hepatitis C virus RNA during antiviral therapy. Hepatology 46 16-21.
    • (2007) Hepatology , vol.46 , pp. 16-21
    • Dahari, H.1    Ribeiro, R.M.2    Perelson, A.S.3
  • 41
    • 0030633357 scopus 로고    scopus 로고
    • Origins, acquisition and dissemination of antibiotic resistance determinants
    • D.J. Chadweick, J. Goode (Eds), New York: John Wiley
    • J.J. Davis (1997) Origins, acquisition and dissemination of antibiotic resistance determinants. D.J. Chadweick, J. Goode (Eds) Antibiotic Resitance: Origins, Evolution, Selection and Spread New York: John Wiley 15-35.
    • (1997) Antibiotic Resitance: Origins, Evolution, Selection and Spread , pp. 15-35
    • Davis, J.J.1
  • 42
    • 34248359479 scopus 로고    scopus 로고
    • Fitness declines in tobacco etch virus upon serial bottleneck transfers
    • F. de la Iglesia and S.F. Elena (2007) Fitness declines in tobacco etch virus upon serial bottleneck transfers. J. Virol. 81 4941-4947.
    • (2007) J. Virol. , vol.81 , pp. 4941-4947
    • de la Iglesia, F.1    Elena, S.F.2
  • 43
    • 0025570214 scopus 로고
    • RNA virus quasispecies populations can suppress vastly superior mutant progeny
    • J.C. de la Torre and J.J. Holland (1990) RNA virus quasispecies populations can suppress vastly superior mutant progeny. J. Virol. 64 6278-6281.
    • (1990) J. Virol. , vol.64 , pp. 6278-6281
    • de la Torre, J.C.1    Holland, J.J.2
  • 44
    • 0347052875 scopus 로고    scopus 로고
    • Mechanistic basis for reduced viral and enzymatic fitness of HIV-1 reverse transcriptase containing both K65R and M184V mutations
    • J. Deval, K.L. White, M.D. Miller, N.T. Parkin, J. Courcambeck, P. Halfon, et al. (2004) Mechanistic basis for reduced viral and enzymatic fitness of HIV-1 reverse transcriptase containing both K65R and M184V mutations. J. Biol. Chem. 279 509-516.
    • (2004) J. Biol. Chem. , vol.279 , pp. 509-516
    • Deval, J.1    White, K.L.2    Miller, M.D.3    Parkin, N.T.4    Courcambeck, J.5    Halfon, P.6
  • 45
    • 11144330097 scopus 로고    scopus 로고
    • Modelling how ribavirin improves interferon response rates in hepatitis C virus infection
    • N.M. Dixit, J.E. Layden-Almer, T.J. Layden and A.S. Perelson (2004) Modelling how ribavirin improves interferon response rates in hepatitis C virus infection. Nature 432 922-924.
    • (2004) Nature , vol.432 , pp. 922-924
    • Dixit, N.M.1    Layden-Almer, J.E.2    Layden, T.J.3    Perelson, A.S.4
  • 46
    • 0034630910 scopus 로고    scopus 로고
    • Viruses at the edge of adaptation
    • E. Domingo (2000) Viruses at the edge of adaptation. Virology 270 251-253.
    • (2000) Virology , vol.270 , pp. 251-253
    • Domingo, E.1
  • 47
    • 30744437878 scopus 로고    scopus 로고
    • Virus entry into error catastrophe as a new antiviral strategy.
    • Domingo, E., ed., (2005[AU12])
    • Domingo, E., ed. (2005[AU12]) Virus entry into error catastrophe as a new antiviral strategy. Virus Res. 107, 115–228.
    • Virus Res. , vol.107 , pp. 115-228
  • 48
    • 30644474782 scopus 로고    scopus 로고
    • Quasispecies: concepts and implications for virology.
    • Domingo, E., ed
    • Domingo, E., ed. (2006) Quasispecies: concepts and implications for virology. Curr. Top. Microbiol. Immunol. 299.
    • (2006) Curr. Top. Microbiol. Immunol. , vol.299
  • 49
    • 38349178145 scopus 로고    scopus 로고
    • Virus evolution
    • D.M. Knipe, P.M. Howley, et al., (Eds), 5th ed., Philadelphia: Lippincott Williams & Wilkins
    • E. Domingo (2007) Virus evolution. D.M. Knipe, P.M. Howley, et al., (Eds) Fields Virology 5th ed. Philadelphia: Lippincott Williams & Wilkins 389-421.
    • (2007) Fields Virology , pp. 389-421
    • Domingo, E.1
  • 50
    • 34447320468 scopus 로고    scopus 로고
    • Quasispecies and its impact on viral hepatitis
    • E. Domingo and J. Gomez (2007) Quasispecies and its impact on viral hepatitis. Virus Res. 127 131-150.
    • (2007) Virus Res. , vol.127 , pp. 131-150
    • Domingo, E.1    Gomez, J.2
  • 51
    • 0030747157 scopus 로고    scopus 로고
    • RNA virus mutations and fitness for survival
    • E. Domingo and J.J. Holland (1997) RNA virus mutations and fitness for survival. Annu. Rev. Microbiol. 51 151-178.
    • (1997) Annu. Rev. Microbiol. , vol.51 , pp. 151-178
    • Domingo, E.1    Holland, J.J.2
  • 52
    • 0017051073 scopus 로고
    • In vitro site-directed mutagenesis: generation and properties of an infectious extracistronic mutant of bacteriophage Qb
    • E. Domingo, R.A. Flavell and C. Weissmann (1976) In vitro site-directed mutagenesis: generation and properties of an infectious extracistronic mutant of bacteriophage Qb. Gene 1 3-25.
    • (1976) Gene , vol.1 , pp. 3-25
    • Domingo, E.1    Flavell, R.A.2    Weissmann, C.3
  • 53
    • 0017806301 scopus 로고
    • Nucleotide sequence heterogeneity of an RNA phage population
    • E. Domingo, D. Sabo, T. Taniguchi and C. Weissmann (1978) Nucleotide sequence heterogeneity of an RNA phage population. Cell 13 735-744.
    • (1978) Cell , vol.13 , pp. 735-744
    • Domingo, E.1    Sabo, D.2    Taniguchi, T.3    Weissmann, C.4
  • 54
    • 27644510382 scopus 로고    scopus 로고
    • Maraviroc (UK-427, 857), a potent, orally bioavailable and selective small-molecule inhibitor of chemokine receptor CCR5 with broad-spectrum anti-human immunodeficiency virus type 1 activity
    • P. Dorr, M. Westby, S. Dobbs, P. Griffin, B. Irvine, M. Macartney, et al. (2005) Maraviroc (UK-427, 857), a potent, orally bioavailable and selective small-molecule inhibitor of chemokine receptor CCR5 with broad-spectrum anti-human immunodeficiency virus type 1 activity. Antimicrob. Agents Chemother. 49 4721-4732.
    • (2005) Antimicrob. Agents Chemother. , vol.49 , pp. 4721-4732
    • Dorr, P.1    Westby, M.2    Dobbs, S.3    Griffin, P.4    Irvine, B.5    Macartney, M.6
  • 55
    • 0029899093 scopus 로고    scopus 로고
    • Second locus involved in human immunodeficiency virus type 1 resistance to protease inhibitors
    • L. Doyon, G. Croteau, D. Thibeault, F. Poulin, L. Pilote and D. Lamarre (1996) Second locus involved in human immunodeficiency virus type 1 resistance to protease inhibitors. J. Virol. 70 3763-3769.
    • (1996) J. Virol. , vol.70 , pp. 3763-3769
    • Doyon, L.1    Croteau, G.2    Thibeault, D.3    Poulin, F.4    Pilote, L.5    Lamarre, D.6
  • 56
    • 0031748806 scopus 로고    scopus 로고
    • Novel Gag-Pol frameshift site in human immunodeficiency virus type 1 variants resistant to protease inhibitors
    • L. Doyon, C. Payant, L. Brakier-Gingras and D. Lamarre (1998) Novel Gag-Pol frameshift site in human immunodeficiency virus type 1 variants resistant to protease inhibitors. J. Virol. 72 6146-6150.
    • (1998) J. Virol. , vol.72 , pp. 6146-6150
    • Doyon, L.1    Payant, C.2    Brakier-Gingras, L.3    Lamarre, D.4
  • 57
    • 0027221640 scopus 로고
    • Rates of spontaneous mutation among RNA viruses
    • J.W. Drake (1993) Rates of spontaneous mutation among RNA viruses. Proc. Natl Acad. Sci. USA 90 4171-4175.
    • (1993) Proc. Natl Acad. Sci. USA , vol.90 , pp. 4171-4175
    • Drake, J.W.1
  • 60
    • 0026729636 scopus 로고
    • Rapid fitness losses in mammalian RNA virus clones due to Muller's ratchet
    • E. Duarte, D. Clarke, A. Moya, E. Domingo and J. Holland (1992) Rapid fitness losses in mammalian RNA virus clones due to Muller's ratchet. Proc. Natl Acad. Sci. USA 89 6015-6019.
    • (1992) Proc. Natl Acad. Sci. USA , vol.89 , pp. 6015-6019
    • Duarte, E.1    Clarke, D.2    Moya, A.3    Domingo, E.4    Holland, J.5
  • 63
    • 0035811838 scopus 로고    scopus 로고
    • Impact of clinical reverse transcriptase sequences on the replication capacity of HIV-1 drug-resistant mutants
    • C. Dykes, K. Fox, A. Lloyd, M. Chiulli, E. Morse and L.M. Demeter (2001) Impact of clinical reverse transcriptase sequences on the replication capacity of HIV-1 drug-resistant mutants. Virology 285 193-203.
    • (2001) Virology , vol.285 , pp. 193-203
    • Dykes, C.1    Fox, K.2    Lloyd, A.3    Chiulli, M.4    Morse, E.5    Demeter, L.M.6
  • 64
    • 0031950370 scopus 로고    scopus 로고
    • Genotypic changes in human immunodeficiency virus type 1 associated with loss of suppression of plasma viral RNA levels in subjects treated with ritonavir (Norvir) monotherapy
    • P.S. Eastman, J. Mittler, R. Kelso, C. Gee, E. Boyer, J. Kolberg, et al. (1998) Genotypic changes in human immunodeficiency virus type 1 associated with loss of suppression of plasma viral RNA levels in subjects treated with ritonavir (Norvir) monotherapy. J. Virol. 72 5154-5164.
    • (1998) J. Virol. , vol.72 , pp. 5154-5164
    • Eastman, P.S.1    Mittler, J.2    Kelso, R.3    Gee, C.4    Boyer, E.5    Kolberg, J.6
  • 65
    • 0015133749 scopus 로고
    • Self-organization of matter and the evolution of biological macromolecules
    • M. Eigen (1971) Self-organization of matter and the evolution of biological macromolecules. Naturwissenschaften 58 465-523.
    • (1971) Naturwissenschaften , vol.58 , pp. 465-523
    • Eigen, M.1
  • 66
    • 0003694580 scopus 로고
    • Oxford: Oxford University Press
    • M. Eigen (1992) Steps towards Life. Oxford: Oxford University Press
    • (1992) Steps towards Life
    • Eigen, M.1
  • 67
    • 0033944978 scopus 로고    scopus 로고
    • Natural selection: a phase transition?
    • M. Eigen (2000) Natural selection: a phase transition? Biophys. Chem. 85 101-123.
    • (2000) Biophys. Chem. , vol.85 , pp. 101-123
    • Eigen, M.1
  • 68
    • 0037108885 scopus 로고    scopus 로고
    • Error catastrophe and antiviral strategy
    • M. Eigen (2002) Error catastrophe and antiviral strategy. Proc. Natl Acad. Sci. USA 99 13374-13376.
    • (2002) Proc. Natl Acad. Sci. USA , vol.99 , pp. 13374-13376
    • Eigen, M.1
  • 69
    • 15544373334 scopus 로고
    • Sequence space and quasispecies distribution
    • E. Domingo, P. Ahlquist, J.J. Holland (Eds), Boca Raton, FL: CRC Press
    • M. Eigen and C.K. Biebricher (1988) Sequence space and quasispecies distribution. E. Domingo, P. Ahlquist, J.J. Holland (Eds) RNA Genetics Vol. 3 Boca Raton, FL: CRC Press 211-245.
    • (1988) RNA Genetics , vol.3 , pp. 211-245
    • Eigen, M.1    Biebricher, C.K.2
  • 72
    • 17144461473 scopus 로고    scopus 로고
    • Multiple molecular pathways for fitness recovery of an RNA virus debilitated by operation of Muller's ratchet
    • C. Escarmís, M. Dávila and E. Domingo (1999) Multiple molecular pathways for fitness recovery of an RNA virus debilitated by operation of Muller's ratchet. J. Mol. Biol. 285 495-505.
    • (1999) J. Mol. Biol. , vol.285 , pp. 495-505
    • Escarmís, C.1    Dávila, M.2    Domingo, E.3
  • 73
    • 0036301071 scopus 로고    scopus 로고
    • Resistance to extinction of low fitness virus subjected to plaque-to- plaque transfers: diversification by mutation clustering
    • C. Escarmís, G. Gómez-Mariano, M. Dávila, E. Lázaro and E. Domingo (2002) Resistance to extinction of low fitness virus subjected to plaque-to- plaque transfers: diversification by mutation clustering. J. Mol. Biol. 315 647-661.
    • (2002) J. Mol. Biol. , vol.315 , pp. 647-661
    • Escarmís, C.1    Gómez-Mariano, G.2    Dávila, M.3    Lázaro, E.4    Domingo, E.5
  • 75
    • 0034646996 scopus 로고    scopus 로고
    • The outcome of acute hepatitis C predicted by the evolution of the viral quasispecies
    • P. Farci, A. Shimoda, A. Coiana, G. Diaz, G. Peddis, J.C. Melpolder, et al. (2000) The outcome of acute hepatitis C predicted by the evolution of the viral quasispecies. Science 288 339-344.
    • (2000) Science , vol.288 , pp. 339-344
    • Farci, P.1    Shimoda, A.2    Coiana, A.3    Diaz, G.4    Peddis, G.5    Melpolder, J.C.6
  • 76
    • 33847210305 scopus 로고    scopus 로고
    • Fitness landscape of human immunodeficiency virus type 1 protease quasispecies
    • G. Fernandez, B. Clotet and M.A. Martinez (2007) Fitness landscape of human immunodeficiency virus type 1 protease quasispecies. J. Virol. 81 2485-2496.
    • (2007) J. Virol. , vol.81 , pp. 2485-2496
    • Fernandez, G.1    Clotet, B.2    Martinez, M.A.3
  • 77
    • 8744222695 scopus 로고    scopus 로고
    • Structure of foot-and-mouth disease virus RNA-dependent RNA polymerase and its complex with a template-primer RNA
    • C. Ferrer-Orta, A. Arias, R. Perez-Luque, C. Escarmis, E. Domingo and N. Verdaguer (2004) Structure of foot-and-mouth disease virus RNA-dependent RNA polymerase and its complex with a template-primer RNA. J. Biol. Chem. 279 47212-47221.
    • (2004) J. Biol. Chem. , vol.279 , pp. 47212-47221
    • Ferrer-Orta, C.1    Arias, A.2    Perez-Luque, R.3    Escarmis, C.4    Domingo, E.5    Verdaguer, N.6
  • 81
    • 34147132711 scopus 로고    scopus 로고
    • Diminished efficiency of HIV-1 reverse transcriptase containing the K65R and M184V drug resistance mutations
    • F.A. Frankel, C.F. Invernizzi, M. Oliveira and M.A. Wainberg (2007) Diminished efficiency of HIV-1 reverse transcriptase containing the K65R and M184V drug resistance mutations. Aids 21 665-675.
    • (2007) Aids , vol.21 , pp. 665-675
    • Frankel, F.A.1    Invernizzi, C.F.2    Oliveira, M.3    Wainberg, M.A.4
  • 84
    • 4143050271 scopus 로고    scopus 로고
    • RIP: the evolutionary cost of genome defense
    • J.E. Galagan and E.U. Selker (2004) RIP: the evolutionary cost of genome defense. Trends Genet. 20 417-423.
    • (2004) Trends Genet. , vol.20 , pp. 417-423
    • Galagan, J.E.1    Selker, E.U.2
  • 85
    • 0035923671 scopus 로고    scopus 로고
    • Increased ability for selection of zidovudine resistance in a distinct class of wild-type HIV-1 from drug-naive persons
    • J.G. Garcia-Lerma, S. Nidtha, K. Blumoff, H. Weinstock and W. Heneine (2001) Increased ability for selection of zidovudine resistance in a distinct class of wild-type HIV-1 from drug-naive persons. Proc. Natl Acad. Sci. USA 98 13907-13912.
    • (2001) Proc. Natl Acad. Sci. USA , vol.98 , pp. 13907-13912
    • Garcia-Lerma, J.G.1    Nidtha, S.2    Blumoff, K.3    Weinstock, H.4    Heneine, W.5
  • 86
    • 6344239125 scopus 로고    scopus 로고
    • Evolutionary transition toward defective RNAs that are infectious by complementation
    • J. García-Arriaza, S.C. Manrubia, M. Toja, E. Domingo and C. Escarmís (2004) Evolutionary transition toward defective RNAs that are infectious by complementation. J. Virol. 78 11678-11685.
    • (2004) J. Virol. , vol.78 , pp. 11678-11685
    • García-Arriaza, J.1    Manrubia, S.C.2    Toja, M.3    Domingo, E.4    Escarmís, C.5
  • 87
    • 17544365671 scopus 로고    scopus 로고
    • A segmented form of foot-and-mouth disease virus interferes with standard virus: a link between interference and competitive fitness
    • J. García-Arriaza, E. Domingo and C. Escarmís (2005) A segmented form of foot-and-mouth disease virus interferes with standard virus: a link between interference and competitive fitness. Virology 335 155-164.
    • (2005) Virology , vol.335 , pp. 155-164
    • García-Arriaza, J.1    Domingo, E.2    Escarmís, C.3
  • 88
    • 33745663489 scopus 로고    scopus 로고
    • Dynamics of mutation and recombination in a replicating population of complementing, defective viral genomes
    • J. García-Arriaza, S. Ojosnegros, M. Dávila, E. Domingo and C. Escarmis (2006) Dynamics of mutation and recombination in a replicating population of complementing, defective viral genomes. J. Mol. Biol. 360 558-572.
    • (2006) J. Mol. Biol. , vol.360 , pp. 558-572
    • García-Arriaza, J.1    Ojosnegros, S.2    Dávila, M.3    Domingo, E.4    Escarmis, C.5
  • 89
    • 35348887750 scopus 로고    scopus 로고
    • Characterization of minority subpopulations in the mutant spectrum of HIV-1 quasispecies by successive specific amplifications
    • J. Garcia-Arriaza, E. Domingo and C. Briones (2007) Characterization of minority subpopulations in the mutant spectrum of HIV-1 quasispecies by successive specific amplifications. Virus Res. 129 123-134.
    • (2007) Virus Res. , vol.129 , pp. 123-134
    • Garcia-Arriaza, J.1    Domingo, E.2    Briones, C.3
  • 90
    • 19244372885 scopus 로고    scopus 로고
    • Transmitted human immunodeficiency virus type 1 carrying the D67N or K219Q/E mutation evolves rapidly to zidovudine resistance in vitro and shows a high replicative fitness in the presence of zidovudine
    • J.G. Garcia-Lerma, H. MacInnes, D. Bennett, H. Weinstock and W. Heneine (2004) Transmitted human immunodeficiency virus type 1 carrying the D67N or K219Q/E mutation evolves rapidly to zidovudine resistance in vitro and shows a high replicative fitness in the presence of zidovudine. J. Virol. 78 7545-7552.
    • (2004) J. Virol. , vol.78 , pp. 7545-7552
    • Garcia-Lerma, J.G.1    MacInnes, H.2    Bennett, D.3    Weinstock, H.4    Heneine, W.5
  • 91
    • 0037155193 scopus 로고    scopus 로고
    • Amino acid substitutions in Gag protein at non-cleavage sites are indispensable for the development of a high multitude of HIV-1 resistance against protease inhibitors
    • H. Gatanaga, Y. Suzuki, H. Tsang, K. Yoshimura, M.F. Kavlick, K. Nagashima, et al. (2002) Amino acid substitutions in Gag protein at non-cleavage sites are indispensable for the development of a high multitude of HIV-1 resistance against protease inhibitors. J. Biol. Chem. 277 5952-5961.
    • (2002) J. Biol. Chem. , vol.277 , pp. 5952-5961
    • Gatanaga, H.1    Suzuki, Y.2    Tsang, H.3    Yoshimura, K.4    Kavlick, M.F.5    Nagashima, K.6
  • 93
    • 34249787638 scopus 로고    scopus 로고
    • Genetic structure and population variability of tomato yellow leaf curl china virus
    • L. Ge, J. Zhang, X. Zhou and H. Li (2007) Genetic structure and population variability of tomato yellow leaf curl china virus. J. Virol. 81 5902-5907.
    • (2007) J. Virol. , vol.81 , pp. 5902-5907
    • Ge, L.1    Zhang, J.2    Zhou, X.3    Li, H.4
  • 94
    • 0032993043 scopus 로고    scopus 로고
    • The P236L delavirdine-resistant human immunodeficiency virus type 1 mutant is replication defective and demonstrates alterations in both RNA 5′-end- and DNA 3′-end-directed RNase H activities
    • P. Gerondelis, R.H. Archer, C. Palaniappan, R.C. Reichman, P.J. Fay, R.A. Bambara and L.M. Demeter (1999) The P236L delavirdine-resistant human immunodeficiency virus type 1 mutant is replication defective and demonstrates alterations in both RNA 5′-end- and DNA 3′-end-directed RNase H activities. J. Virol. 73 5803-5813.
    • (1999) J. Virol. , vol.73 , pp. 5803-5813
    • Gerondelis, P.1    Archer, R.H.2    Palaniappan, C.3    Reichman, R.C.4    Fay, P.J.5    Bambara, R.A.6    Demeter, L.M.7
  • 96
    • 25144524546 scopus 로고    scopus 로고
    • Invariant aphthovirus consensus nucleotide sequence in the transition to error catastrophe
    • C. González-López, G. Gómez-Mariano, C. Escarmís and E. Domingo (2005) Invariant aphthovirus consensus nucleotide sequence in the transition to error catastrophe. Infect. Genet. Evol. 5 366-374.
    • (2005) Infect. Genet. Evol. , vol.5 , pp. 366-374
    • González-López, C.1    Gómez-Mariano, G.2    Escarmís, C.3    Domingo, E.4
  • 97
    • 0031917762 scopus 로고    scopus 로고
    • DNA polymerase fidelity: from genetics toward a biochemical understanding
    • M.F. Goodman and K.D. Fygenson (1998) DNA polymerase fidelity: from genetics toward a biochemical understanding. Genetics 148 1475-1482.
    • (1998) Genetics , vol.148 , pp. 1475-1482
    • Goodman, M.F.1    Fygenson, K.D.2
  • 98
    • 0003766346 scopus 로고
    • Origin of RNA viral genomes; approaching the problem by comparative sequence analysis
    • A. Gibbs, C.H. Calisher, F. Garcia-Arenal (Eds), Cambridge: Cambridge University Press
    • A.E. Gorbalenya (1995) Origin of RNA viral genomes; approaching the problem by comparative sequence analysis. A. Gibbs, C.H. Calisher, F. Garcia-Arenal (Eds) Molecular Basis of Virus Evolution Cambridge: Cambridge University Press 49-66.
    • (1995) Molecular Basis of Virus Evolution , pp. 49-66
    • Gorbalenya, A.E.1
  • 99
    • 0030926277 scopus 로고    scopus 로고
    • Broad spectrum of in vivo fitness of human immunodeficiency virus type 1 subpopulations differing at reverse transcriptase codons 41 and 215
    • J. Goudsmit, A. de Ronde, E. de Rooij and R. de Boer (1997) Broad spectrum of in vivo fitness of human immunodeficiency virus type 1 subpopulations differing at reverse transcriptase codons 41 and 215. J. Virol. 71 4479-4484.
    • (1997) J. Virol. , vol.71 , pp. 4479-4484
    • Goudsmit, J.1    de Ronde, A.2    de Rooij, E.3    de Boer, R.4
  • 100
    • 0036789885 scopus 로고    scopus 로고
    • Molecular indetermination in the transition to error catastrophe: systematic elimination of lymphocytic choriomeningitis virus through mutagenesis does not correlate linearly with large increases in mutant spectrum complexity
    • A. Grande-Pérez, S. Sierra, M.G. Castro, E. Domingo and P.R. Lowenstein (2002) Molecular indetermination in the transition to error catastrophe: systematic elimination of lymphocytic choriomeningitis virus through mutagenesis does not correlate linearly with large increases in mutant spectrum complexity. Proc. Natl Acad. Sci. USA 99 12938-12943.
    • (2002) Proc. Natl Acad. Sci. USA , vol.99 , pp. 12938-12943
    • Grande-Pérez, A.1    Sierra, S.2    Castro, M.G.3    Domingo, E.4    Lowenstein, P.R.5
  • 101
    • 23244443638 scopus 로고    scopus 로고
    • Mutagenesis-induced, large fitness variations with an invariant arenavirus consensus genomic nucleotide sequence
    • A. Grande-Pérez, G. Gómez-Mariano, P.R. Lowenstein and E. Domingo (2005) Mutagenesis-induced, large fitness variations with an invariant arenavirus consensus genomic nucleotide sequence. J. Virol. 79 10451-10459.
    • (2005) J. Virol. , vol.79 , pp. 10451-10459
    • Grande-Pérez, A.1    Gómez-Mariano, G.2    Lowenstein, P.R.3    Domingo, E.4
  • 103
    • 27644543076 scopus 로고    scopus 로고
    • Effect of alternating passage on adaptation of sindbis virus to vertebrate and invertebrate cells
    • I.P. Greene, E. Wang, E.R. Deardorff, R. Milleron, E. Domingo and S.C. Weaver (2005) Effect of alternating passage on adaptation of sindbis virus to vertebrate and invertebrate cells. J. Virol. 79 14253-14260.
    • (2005) J. Virol. , vol.79 , pp. 14253-14260
    • Greene, I.P.1    Wang, E.2    Deardorff, E.R.3    Milleron, R.4    Domingo, E.5    Weaver, S.C.6
  • 104
    • 34249857885 scopus 로고    scopus 로고
    • Replication fitness determines high virulence of influenza A virus in mice carrying functional Mx1 resistance gene
    • D. Grimm, P. Staeheli, M. Hufbauer, I. Koerner, L. Martinez-Sobrido, A. Solorzano, et al. (2007) Replication fitness determines high virulence of influenza A virus in mice carrying functional Mx1 resistance gene. Proc. Natl Acad. Sci. USA 104 6806-6811.
    • (2007) Proc. Natl Acad. Sci. USA , vol.104 , pp. 6806-6811
    • Grimm, D.1    Staeheli, P.2    Hufbauer, M.3    Koerner, I.4    Martinez-Sobrido, L.5    Solorzano, A.6
  • 105
    • 0031958266 scopus 로고    scopus 로고
    • Relative replicative fitness of zidovudine-resistant human immunodeficiency virus type 1 isolates in vitro
    • P.R. Harrigan, S. Bloor and B.A. Larder (1998) Relative replicative fitness of zidovudine-resistant human immunodeficiency virus type 1 isolates in vitro. J. Virol. 72 3773-3778.
    • (1998) J. Virol. , vol.72 , pp. 3773-3778
    • Harrigan, P.R.1    Bloor, S.2    Larder, B.A.3
  • 106
    • 20444414897 scopus 로고    scopus 로고
    • KP-1212/1461, a nucleoside designed for the treatment of HIV by viral mutagenesis
    • K.S. Harris, W. Brabant, S. Styrchak, A. Gall and R. Daifuku (2005) KP-1212/1461, a nucleoside designed for the treatment of HIV by viral mutagenesis. Antiviral Res. 67 1-9.
    • (2005) Antiviral Res. , vol.67 , pp. 1-9
    • Harris, K.S.1    Brabant, W.2    Styrchak, S.3    Gall, A.4    Daifuku, R.5
  • 107
    • 34247623284 scopus 로고    scopus 로고
    • Molecular basis for a lack of correlation between viral fitness and cell killing capacity
    • M. Herrera, J. Garcia-Arriaza, N. Pariente, C. Escarmis and E. Domingo (2007) Molecular basis for a lack of correlation between viral fitness and cell killing capacity. PLoS Pathog. 3 e53.
    • (2007) PLoS Pathog. , vol.3 , pp. e53
    • Herrera, M.1    Garcia-Arriaza, J.2    Pariente, N.3    Escarmis, C.4    Domingo, E.5
  • 108
    • 0000743310 scopus 로고
    • The role of gene transfer in the evolution of eukaryotic sex
    • R.E. Michod, B.R. Levin (Eds), Sunderland, MA: Sinauer
    • D.A. Hickey and M.R. Rose (1988) The role of gene transfer in the evolution of eukaryotic sex. R.E. Michod, B.R. Levin (Eds) The Evolution of Sex Sunderland, MA: Sinauer 161-175.
    • (1988) The Evolution of Sex , pp. 161-175
    • Hickey, D.A.1    Rose, M.R.2
  • 109
    • 0031905556 scopus 로고    scopus 로고
    • Origin and evolution of viruses
    • J. Holland and E. Domingo (1998) Origin and evolution of viruses. Virus Genes 16 13-21.
    • (1998) Virus Genes , vol.16 , pp. 13-21
    • Holland, J.1    Domingo, E.2
  • 111
    • 0025284804 scopus 로고
    • Mutation frequencies at defined single codon sites in vesicular stomatitis virus and poliovirus can be increased only slightly by chemical mutagenesis
    • J.J. Holland, E. Domingo, J.C. de la Torre and D.A. Steinhauer (1990) Mutation frequencies at defined single codon sites in vesicular stomatitis virus and poliovirus can be increased only slightly by chemical mutagenesis. J. Virol. 64 3960-3962.
    • (1990) J. Virol. , vol.64 , pp. 3960-3962
    • Holland, J.J.1    Domingo, E.2    de la Torre, J.C.3    Steinhauer, D.A.4
  • 112
    • 0026070176 scopus 로고
    • Quantitation of relative fitness and great adaptability of clonal populations of RNA viruses
    • J.J. Holland, J.C. de la Torre, D.K. Clarke and E. Duarte (1991) Quantitation of relative fitness and great adaptability of clonal populations of RNA viruses. J. Virol. 65 2960-2967.
    • (1991) J. Virol. , vol.65 , pp. 2960-2967
    • Holland, J.J.1    de la Torre, J.C.2    Clarke, D.K.3    Duarte, E.4
  • 113
    • 33745778007 scopus 로고    scopus 로고
    • Fitness comparison of thymidine analog resistance pathways in human immunodeficiency virus type 1
    • Z. Hu, F. Giguel, H. Hatano, P. Reid, J. Lu and D.R. Kuritzkes (2006) Fitness comparison of thymidine analog resistance pathways in human immunodeficiency virus type 1. J. Virol. 80 7020-7027.
    • (2006) J. Virol. , vol.80 , pp. 7020-7027
    • Hu, Z.1    Giguel, F.2    Hatano, H.3    Reid, P.4    Lu, J.5    Kuritzkes, D.R.6
  • 114
    • 0037223722 scopus 로고    scopus 로고
    • Amino acid substitutions at position 190 of human immunodeficiency virus type 1 reverse transcriptase increase susceptibility to delavirdine and impair virus replication
    • W. Huang, A. Gamarnik, K. Limoli, C.J. Petropoulos and J.M. Whitcomb (2003) Amino acid substitutions at position 190 of human immunodeficiency virus type 1 reverse transcriptase increase susceptibility to delavirdine and impair virus replication. J. Virol. 77 1512-1523.
    • (2003) J. Virol. , vol.77 , pp. 1512-1523
    • Huang, W.1    Gamarnik, A.2    Limoli, K.3    Petropoulos, C.J.4    Whitcomb, J.M.5
  • 115
    • 0037696057 scopus 로고    scopus 로고
    • Modeling HIV dynamics and antiviral response with consideration of time-varying drug exposures, adherence and phenotypic sensitivity
    • Y. Huang, S.L. Rosenkranz and H. Wu (2003) Modeling HIV dynamics and antiviral response with consideration of time-varying drug exposures, adherence and phenotypic sensitivity. Math. Biosci. 184 165-186.
    • (2003) Math. Biosci. , vol.184 , pp. 165-186
    • Huang, Y.1    Rosenkranz, S.L.2    Wu, H.3
  • 116
    • 0030030533 scopus 로고    scopus 로고
    • Smoothness within ruggedness: the role of neutrality in adaptation
    • M.A. Huynen, P.F. Stadler and W. Fontana (1996) Smoothness within ruggedness: the role of neutrality in adaptation. Proc. Natl Acad. Sci. USA 93 397-401.
    • (1996) Proc. Natl Acad. Sci. USA , vol.93 , pp. 397-401
    • Huynen, M.A.1    Stadler, P.F.2    Fontana, W.3
  • 117
    • 0036135710 scopus 로고    scopus 로고
    • In vitro analysis of human immunodeficiency virus type 1 resistance to nevirapine and fitness determination of resistant variants
    • M.D. Iglesias-Ussel, C. Casado, E. Yuste, I. Olivares and C. Lopez-Galindez (2002) In vitro analysis of human immunodeficiency virus type 1 resistance to nevirapine and fitness determination of resistant variants. J. Gen. Virol. 83 93-101.
    • (2002) J. Gen. Virol. , vol.83 , pp. 93-101
    • Iglesias-Ussel, M.D.1    Casado, C.2    Yuste, E.3    Olivares, I.4    Lopez-Galindez, C.5
  • 118
    • 0022838916 scopus 로고
    • Proofreading function associated with the RNA-dependent RNA polymerase from influenza virus
    • A. Ishihama, K. Mizumoto, K. Kawakami, A. Kato and A. Honda (1986) Proofreading function associated with the RNA-dependent RNA polymerase from influenza virus. J. Biol. Chem. 261 10417-10421.
    • (1986) J. Biol. Chem. , vol.261 , pp. 10417-10421
    • Ishihama, A.1    Mizumoto, K.2    Kawakami, K.3    Kato, A.4    Honda, A.5
  • 119
    • 0030048748 scopus 로고    scopus 로고
    • Multidrug-resistant human immunodeficiency virus type 1 strains resulting from combination antiretroviral therapy
    • A.K. Iversen, R.W. Shafer, K. Wehrly, M.A. Winters, J.I. Mullins, B. Chesebro and T.C. Merigan (1996) Multidrug-resistant human immunodeficiency virus type 1 strains resulting from combination antiretroviral therapy. J. Virol. 70 1086-1090.
    • (1996) J. Virol. , vol.70 , pp. 1086-1090
    • Iversen, A.K.1    Shafer, R.W.2    Wehrly, K.3    Winters, M.A.4    Mullins, J.I.5    Chesebro, B.6    Merigan, T.C.7
  • 120
    • 0035837049 scopus 로고    scopus 로고
    • Evolution of AZT resistance in HIV-1: the 41–70 intermediate that is not observed in vivo has a replication defect
    • R.E. Jeeninga, W. Keulen, C. Boucher, R.W. Sanders and B. Berkhout (2001) Evolution of AZT resistance in HIV-1: the 41–70 intermediate that is not observed in vivo has a replication defect. Virology 283 294-305.
    • (2001) Virology , vol.283 , pp. 294-305
    • Jeeninga, R.E.1    Keulen, W.2    Boucher, C.3    Sanders, R.W.4    Berkhout, B.5
  • 122
    • 33144462048 scopus 로고    scopus 로고
    • Distinct viral populations differentiate and evolve independently in a single perennial host plant
    • C. Jridi, J.F. Martin, V. Marie-Jeanne, G. Labonne and S. Blanc (2006) Distinct viral populations differentiate and evolve independently in a single perennial host plant. J. Virol. 80 2349-2357.
    • (2006) J. Virol. , vol.80 , pp. 2349-2357
    • Jridi, C.1    Martin, J.F.2    Marie-Jeanne, V.3    Labonne, G.4    Blanc, S.5
  • 124
    • 0031775017 scopus 로고    scopus 로고
    • Diverse host responses and outcomes following simian immunodeficiency virus SIVmac239 infection in sooty mangabeys and rhesus macaques
    • A. Kaur, R.M. Grant, R.E. Means, H. McClure, M. Feinberg and R.P. Johnson (1998) Diverse host responses and outcomes following simian immunodeficiency virus SIVmac239 infection in sooty mangabeys and rhesus macaques. J. Virol. 72 9597-9611.
    • (1998) J. Virol. , vol.72 , pp. 9597-9611
    • Kaur, A.1    Grant, R.M.2    Means, R.E.3    McClure, H.4    Feinberg, M.5    Johnson, R.P.6
  • 125
    • 0030896362 scopus 로고    scopus 로고
    • Initial appearance of the 184Ile variant in lamivudine-treated patients is caused by the mutational bias of human immunodeficiency virus type 1 reverse transcriptase
    • W. Keulen, N.K. Back, A. van Wijk, C.A. Boucher and B. Berkhout (1997) Initial appearance of the 184Ile variant in lamivudine-treated patients is caused by the mutational bias of human immunodeficiency virus type 1 reverse transcriptase. J. Virol. 71 3346-3350.
    • (1997) J. Virol. , vol.71 , pp. 3346-3350
    • Keulen, W.1    Back, N.K.2    van Wijk, A.3    Boucher, C.A.4    Berkhout, B.5
  • 126
    • 0032922339 scopus 로고    scopus 로고
    • Emerging cytopathic and antigenic simian immunodeficiency virus variants influence AIDS progression
    • J.T. Kimata, L. Kuller, D.B. Anderson, P. Dailey and J. Overbaugh (1999) Emerging cytopathic and antigenic simian immunodeficiency virus variants influence AIDS progression. Nat. Med. 5 535-541.
    • (1999) Nat. Med. , vol.5 , pp. 535-541
    • Kimata, J.T.1    Kuller, L.2    Anderson, D.B.3    Dailey, P.4    Overbaugh, J.5
  • 127
    • 0026693137 scopus 로고
    • Crystal structure at 3, 5 A resolution of HIV-1 reverse transcriptase complexed with an inhibitor
    • L.A. Kohlstaedt, J. Wang, J.M. Friedman, P.A. Rice and T.A. Steitz (1992) Crystal structure at 3, 5 A resolution of HIV-1 reverse transcriptase complexed with an inhibitor. Science 256 1783-1790.
    • (1992) Science , vol.256 , pp. 1783-1790
    • Kohlstaedt, L.A.1    Wang, J.2    Friedman, J.M.3    Rice, P.A.4    Steitz, T.A.5
  • 128
    • 21444456320 scopus 로고    scopus 로고
    • Paramyxovirus mRNA editing, the “rule of six” and error catastrophe: a hypothesis
    • D. Kolakofsky, L. Roux, D. Garcin and R.W. Ruigrok (2005) Paramyxovirus mRNA editing, the “rule of six” and error catastrophe: a hypothesis. J. Gen. Virol. 86 1869-1877.
    • (2005) J. Gen. Virol. , vol.86 , pp. 1869-1877
    • Kolakofsky, D.1    Roux, L.2    Garcin, D.3    Ruigrok, R.W.4
  • 129
  • 130
    • 0033064963 scopus 로고    scopus 로고
    • Comparative fitness of multi-dideoxynucleoside-resistant human immunodeficiency virus type 1 (HIV-1) in an In vitro competitive HIV-1 replication assay
    • P. Kosalaraksa, M.F. Kavlick, V. Maroun, R. Le and H. Mitsuya (1999) Comparative fitness of multi-dideoxynucleoside-resistant human immunodeficiency virus type 1 (HIV-1) in an In vitro competitive HIV-1 replication assay. J. Virol. 73 5356-5363.
    • (1999) J. Virol. , vol.73 , pp. 5356-5363
    • Kosalaraksa, P.1    Kavlick, M.F.2    Maroun, V.3    Le, R.4    Mitsuya, H.5
  • 131
    • 0025109103 scopus 로고
    • Misalignment-mediated DNA synthesis errors
    • T.A. Kunkel (1990) Misalignment-mediated DNA synthesis errors. Biochemistry 29 8003-8011.
    • (1990) Biochemistry , vol.29 , pp. 8003-8011
    • Kunkel, T.A.1
  • 132
    • 0028323494 scopus 로고
    • Interactions between drug resistance mutations in human immunodeficiency virus type 1 reverse transcriptase
    • B.A. Larder (1994) Interactions between drug resistance mutations in human immunodeficiency virus type 1 reverse transcriptase. J. Gen. Virol. 75(Pt 5), 951-957.
    • (1994) J. Gen. Virol. , vol.75 , pp. 951-957
    • Larder, B.A.1
  • 133
    • 0024508058 scopus 로고
    • HIV with reduced sensitivity to zidovudine (AZT) isolated during prolonged therapy
    • B.A. Larder, G. Darby and D.D. Richman (1989) HIV with reduced sensitivity to zidovudine (AZT) isolated during prolonged therapy. Science 243 1731-1734.
    • (1989) Science , vol.243 , pp. 1731-1734
    • Larder, B.A.1    Darby, G.2    Richman, D.D.3
  • 134
    • 0141633021 scopus 로고    scopus 로고
    • Resistance of virus to extinction on bottleneck passages: Study of a decaying and fluctuating pattern of fitness loss
    • E. Lazaro, C. Escarmis, J. Perez-Mercader, S.C. Manrubia and E. Domingo (2003) Resistance of virus to extinction on bottleneck passages: Study of a decaying and fluctuating pattern of fitness loss. Proc. Natl Acad. Sci. USA 100 10830-10835.
    • (2003) Proc. Natl Acad. Sci. USA , vol.100 , pp. 10830-10835
    • Lazaro, E.1    Escarmis, C.2    Perez-Mercader, J.3    Manrubia, S.C.4    Domingo, E.5
  • 135
    • 76449100579 scopus 로고    scopus 로고
    • Plant viruses
    • D.M. Dnipe, P.M. Howley (Eds), Philadelphia: Lippincot Williams and Wilkins
    • S.D. Lazarowitz (2007) Plant viruses. D.M. Dnipe, P.M. Howley (Eds) Fields Virology Philadelphia: Lippincot Williams and Wilkins 641-705.
    • (2007) Fields Virology , pp. 641-705
    • Lazarowitz, S.D.1
  • 136
    • 0030952877 scopus 로고    scopus 로고
    • Negative effects of chemical mutagenesis on the adaptive behavior of vesicular stomatitis virus
    • C.H. Lee, D.L. Gilbertson, I.S. Novella, R. Huerta, E. Domingo and J.J. Holland (1997) Negative effects of chemical mutagenesis on the adaptive behavior of vesicular stomatitis virus. J. Virol. 71 3636-3640.
    • (1997) J. Virol. , vol.71 , pp. 3636-3640
    • Lee, C.H.1    Gilbertson, D.L.2    Novella, I.S.3    Huerta, R.4    Domingo, E.5    Holland, J.J.6
  • 137
    • 0030807901 scopus 로고    scopus 로고
    • Novel and dynamic evolution of equine infectious anemia virus genomic quasispecies associated with sequential disease cycles in an experimentally infected pony
    • C. Leroux, C.J. Issel and R.C. Montelaro (1997) Novel and dynamic evolution of equine infectious anemia virus genomic quasispecies associated with sequential disease cycles in an experimentally infected pony. J. Virol. 71 9627-9639.
    • (1997) J. Virol. , vol.71 , pp. 9627-9639
    • Leroux, C.1    Issel, C.J.2    Montelaro, R.C.3
  • 139
    • 3042799046 scopus 로고    scopus 로고
    • Relative replicative fitness of human immunodeficiency virus type 1 mutants resistant to enfuvirtide (T-20)
    • J. Lu, P. Sista, F. Giguel, M. Greenberg and D.R. Kuritzkes (2004) Relative replicative fitness of human immunodeficiency virus type 1 mutants resistant to enfuvirtide (T-20). J. Virol. 78 4628-4637.
    • (2004) J. Virol. , vol.78 , pp. 4628-4637
    • Lu, J.1    Sista, P.2    Giguel, F.3    Greenberg, M.4    Kuritzkes, D.R.5
  • 140
    • 0034914629 scopus 로고    scopus 로고
    • Selection by AZT and rapid replacement in the absence of drugs of HIV type 1 resistant to multiple nucleoside analogs
    • V.V. Lukashov, R. Huismans, M.F. Jebbink, S.A. Danner, R.J. de Boer and J. Goudsmit (2001) Selection by AZT and rapid replacement in the absence of drugs of HIV type 1 resistant to multiple nucleoside analogs. AIDS Res. Hum. Retroviruses 17 807-818.
    • (2001) AIDS Res. Hum. Retroviruses , vol.17 , pp. 807-818
    • Lukashov, V.V.1    Huismans, R.2    Jebbink, M.F.3    Danner, S.A.4    de Boer, R.J.5    Goudsmit, J.6
  • 141
    • 0031948662 scopus 로고    scopus 로고
    • Altered drug sensitivity, fitness and evolution of human immunodeficiency virus type 1 with pol gene mutations conferring multi-dideoxynucleoside resistance
    • Y. Maeda, D.J. Venzon and H. Mitsuya (1998) Altered drug sensitivity, fitness and evolution of human immunodeficiency virus type 1 with pol gene mutations conferring multi-dideoxynucleoside resistance. J. Infect. Dis. 177 1207-1213.
    • (1998) J. Infect. Dis. , vol.177 , pp. 1207-1213
    • Maeda, Y.1    Venzon, D.J.2    Mitsuya, H.3
  • 142
    • 15544380169 scopus 로고    scopus 로고
    • High mutation rates, bottlenecks and robustness of RNA viral quasispecies
    • S.C. Manrubia, C. Escarmis, E. Domingo and E. Lazaro (2005) High mutation rates, bottlenecks and robustness of RNA viral quasispecies. Gene 347 273-282.
    • (2005) Gene , vol.347 , pp. 273-282
    • Manrubia, S.C.1    Escarmis, C.2    Domingo, E.3    Lazaro, E.4
  • 143
    • 33646419810 scopus 로고    scopus 로고
    • Long-range transport and universality classes in in vitro viral infection spread
    • S.C. Manrubia, J. Garcia-Arriaza, E. Domingo and C. Escarmís (2006) Long-range transport and universality classes in in vitro viral infection spread. Europhys. Lett. 74 547-553.
    • (2006) Europhys. Lett. , vol.74 , pp. 547-553
    • Manrubia, S.C.1    Garcia-Arriaza, J.2    Domingo, E.3    Escarmís, C.4
  • 144
    • 0031974477 scopus 로고    scopus 로고
    • Interferon induction as a quasispecies marker of vesicular stomatitis virus populations
    • P.I. Marcus, L.L. Rodriguez and M.J. Sekellick (1998) Interferon induction as a quasispecies marker of vesicular stomatitis virus populations. J. Virol. 72 542-549.
    • (1998) J. Virol. , vol.72 , pp. 542-549
    • Marcus, P.I.1    Rodriguez, L.L.2    Sekellick, M.J.3
  • 145
    • 0032928065 scopus 로고    scopus 로고
    • Replicative fitness of protease inhibitor-resistant mutants of human immunodeficiency virus type 1
    • J. Martinez-Picado, A.V. Savara, L. Sutton and R.T. D'Aquila (1999) Replicative fitness of protease inhibitor-resistant mutants of human immunodeficiency virus type 1. J. Virol. 73 3744-3752.
    • (1999) J. Virol. , vol.73 , pp. 3744-3752
    • Martinez-Picado, J.1    Savara, A.V.2    Sutton, L.3    D'Aquila, R.T.4
  • 146
    • 0025886357 scopus 로고
    • Fitness alteration of foot-and-mouth disease virus mutants: measurement of adaptability of viral quasispecies
    • M.A. Martinez, C. Carrillo, F. Gonzalez-Candelas, A. Moya, E. Domingo and F. Sobrino (1991) Fitness alteration of foot-and-mouth disease virus mutants: measurement of adaptability of viral quasispecies. J. Virol. 65 3954-3957.
    • (1991) J. Virol. , vol.65 , pp. 3954-3957
    • Martinez, M.A.1    Carrillo, C.2    Gonzalez-Candelas, F.3    Moya, A.4    Domingo, E.5    Sobrino, F.6
  • 147
    • 0034329473 scopus 로고    scopus 로고
    • Role of a dipeptide insertion between codons 69–70 of HIV-1 reverse transcriptase in the mechanism of AZT resistance
    • A. Mas, M. Parera, C. Briones, V. Soriano, M.A. Martínez, E. Domingo and L. Menéndez-Arias (2000) Role of a dipeptide insertion between codons 69–70 of HIV-1 reverse transcriptase in the mechanism of AZT resistance. EMBO J. 19 5752-5761.
    • (2000) EMBO J. , vol.19 , pp. 5752-5761
    • Mas, A.1    Parera, M.2    Briones, C.3    Soriano, V.4    Martínez, M.A.5    Domingo, E.6    Menéndez-Arias, L.7
  • 148
    • 2642518791 scopus 로고    scopus 로고
    • Molecular determinants of multi-nucleoside analogue resistance in HIV-1 reverse transcriptases containing a dipeptide insertion in the fingers subdomain: effect of mutations D67N and T215Y on removal of thymidine nucleotide analogues from blocked DNA primers
    • T. Matamoros, S. Franco, B.M. Vazquez-Alvarez, A. Mas, M.A. Martinez and L. Menendez-Arias (2004) Molecular determinants of multi-nucleoside analogue resistance in HIV-1 reverse transcriptases containing a dipeptide insertion in the fingers subdomain: effect of mutations D67N and T215Y on removal of thymidine nucleotide analogues from blocked DNA primers. J. Biol. Chem. 279 24569-24577.
    • (2004) J. Biol. Chem. , vol.279 , pp. 24569-24577
    • Matamoros, T.1    Franco, S.2    Vazquez-Alvarez, B.M.3    Mas, A.4    Martinez, M.A.5    Menendez-Arias, L.6
  • 151
    • 0036696712 scopus 로고    scopus 로고
    • Targeting HIV: antiretroviral therapy and development of drug resistance
    • L. Menendez-Arias (2002) Targeting HIV: antiretroviral therapy and development of drug resistance. Trends Pharmacol. Sci. 23 381-388.
    • (2002) Trends Pharmacol. Sci. , vol.23 , pp. 381-388
    • Menendez-Arias, L.1
  • 152
    • 33646528913 scopus 로고    scopus 로고
    • Insertions and deletions in HIV-1 reverse transcriptase: consequences for drug resistance and viral fitness
    • L. Menendez-Arias, T. Matamoros and C.E. Cases-Gonzalez (2006) Insertions and deletions in HIV-1 reverse transcriptase: consequences for drug resistance and viral fitness. Curr. Pharm. Des. 12 1811-1825.
    • (2006) Curr. Pharm. Des. , vol.12 , pp. 1811-1825
    • Menendez-Arias, L.1    Matamoros, T.2    Cases-Gonzalez, C.E.3
  • 154
    • 0031848831 scopus 로고    scopus 로고
    • Human immunodeficiency virus type 1 reverse transcriptase expressing the K70E mutation exhibits a decrease in specific activity and processivity
    • M.D. Miller, P.D. Lamy, M.D. Fuller, A.S. Mulato, N.A. Margot, T. Cihlar and J.M. Cherrington (1998) Human immunodeficiency virus type 1 reverse transcriptase expressing the K70E mutation exhibits a decrease in specific activity and processivity. Mol. Pharmacol. 54 291-297.
    • (1998) Mol. Pharmacol. , vol.54 , pp. 291-297
    • Miller, M.D.1    Lamy, P.D.2    Fuller, M.D.3    Mulato, A.S.4    Margot, N.A.5    Cihlar, T.6    Cherrington, J.M.7
  • 156
    • 0001707601 scopus 로고
    • 3′-Azido-3′-deoxythymidine (BW A509U): an antiviral agent that inhibits the infectivity and cytopathic effect of human T-lymphotropic virus type III/lymphadenopathy-associated virus in vitro
    • H. Mitsuya, K.J. Weinhold, P.A. Furman, M.H. St Clair, S.N. Lehrman, R.C. Gallo, et al. (1985) 3′-Azido-3′-deoxythymidine (BW A509U): an antiviral agent that inhibits the infectivity and cytopathic effect of human T-lymphotropic virus type III/lymphadenopathy-associated virus in vitro. Proc. Natl Acad. Sci. USA 82 7096-7100.
    • (1985) Proc. Natl Acad. Sci. USA , vol.82 , pp. 7096-7100
    • Mitsuya, H.1    Weinhold, K.J.2    Furman, P.A.3    St Clair, M.H.4    Lehrman, S.N.5    Gallo, R.C.6
  • 157
    • 0030729198 scopus 로고    scopus 로고
    • A mutation in tomato aspermy cucumovirus that abolishes cell-to-cell movement is maintained to high levels in the viral RNA population by complementation
    • I.M. Moreno, J.M. Malpica, E. Rodriguez-Cerezo and F. Garcia-Arenal (1997) A mutation in tomato aspermy cucumovirus that abolishes cell-to-cell movement is maintained to high levels in the viral RNA population by complementation. J. Virol. 71 9157-9162.
    • (1997) J. Virol. , vol.71 , pp. 9157-9162
    • Moreno, I.M.1    Malpica, J.M.2    Rodriguez-Cerezo, E.3    Garcia-Arenal, F.4
  • 158
    • 0015842834 scopus 로고
    • Natural selection of mutants of vesicular stomatitis virus by cultured cells of Drosophila melanogaster
    • J.A. Mudd, R.W. Leavitt, D.T. Kingsbury and J.J. Holland (1973) Natural selection of mutants of vesicular stomatitis virus by cultured cells of Drosophila melanogaster. J. Gen. Virol. 20 341-351.
    • (1973) J. Gen. Virol. , vol.20 , pp. 341-351
    • Mudd, J.A.1    Leavitt, R.W.2    Kingsbury, D.T.3    Holland, J.J.4
  • 159
    • 33646706853 scopus 로고    scopus 로고
    • Stable virulence levels in the HIV epidemic of Switzerland over two decades
    • V. Muller, B. Ledergerber, L. Perrin, T. Klimkait, H. Furrer, A. Telenti, et al. (2006) Stable virulence levels in the HIV epidemic of Switzerland over two decades. Aids 20 889-894.
    • (2006) Aids , vol.20 , pp. 889-894
    • Muller, V.1    Ledergerber, B.2    Perrin, L.3    Klimkait, T.4    Furrer, H.5    Telenti, A.6
  • 160
    • 0942290560 scopus 로고    scopus 로고
    • Gag non-cleavage site mutations contribute to full recovery of viral fitness in protease inhibitor-resistant human immunodeficiency virus type 1
    • L. Myint, M. Matsuda, Z. Matsuda, Y. Yokomaku, T. Chiba, A. Okano, et al. (2004) Gag non-cleavage site mutations contribute to full recovery of viral fitness in protease inhibitor-resistant human immunodeficiency virus type 1. Antimicrob. Agents Chemother, 48 444-452.
    • (2004) Antimicrob. Agents Chemother , vol.48 , pp. 444-452
    • Myint, L.1    Matsuda, M.2    Matsuda, Z.3    Yokomaku, Y.4    Chiba, T.5    Okano, A.6
  • 162
    • 0028988479 scopus 로고
    • Pol gene quasispecies of human immunodeficiency virus: mutations associated with drug resistance in virus from patients undergoing no drug therapy
    • I. Nájera, A. Holguín, M.E. Quiñones-Mateu, M.A. Muñoz-Fernández, R. Nájera, C. López-Galíndez and E. Domingo (1995) Pol gene quasispecies of human immunodeficiency virus: mutations associated with drug resistance in virus from patients undergoing no drug therapy. J. Virol. 69 23-31.
    • (1995) J. Virol. , vol.69 , pp. 23-31
    • Nájera, I.1    Holguín, A.2    Quiñones-Mateu, M.E.3    Muñoz-Fernández, M.A.4    Nájera, R.5    López-Galíndez, C.6    Domingo, E.7
  • 163
    • 4444358447 scopus 로고    scopus 로고
    • Molecular basis of fitness loss and fitness recovery in vesicular stomatitis virus
    • I.S. Novella and B.E. Ebendick-Corpus (2004) Molecular basis of fitness loss and fitness recovery in vesicular stomatitis virus. J. Mol. Biol. 342 1423-1430.
    • (2004) J. Mol. Biol. , vol.342 , pp. 1423-1430
    • Novella, I.S.1    Ebendick-Corpus, B.E.2
  • 164
    • 0028838604 scopus 로고
    • Extreme fitness differences in mammalian and insect hosts after continuous replication of vesicular stomatitis virus in sandfly cells
    • I.S. Novella, D.K. Clarke, J. Quer, E.A. Duarte, C.H. Lee, S.C. Weaver, et al. (1995) Extreme fitness differences in mammalian and insect hosts after continuous replication of vesicular stomatitis virus in sandfly cells. J. Virol. 69 6805-6809.
    • (1995) J. Virol. , vol.69 , pp. 6805-6809
    • Novella, I.S.1    Clarke, D.K.2    Quer, J.3    Duarte, E.A.4    Lee, C.H.5    Weaver, S.C.6
  • 166
    • 0028922116 scopus 로고
    • Size of genetic bottlenecks leading to virus fitness loss is determined by mean initial population fitness
    • I.S. Novella, S.F. Elena, A. Moya, E. Domingo and J.J. Holland (1995) Size of genetic bottlenecks leading to virus fitness loss is determined by mean initial population fitness. J. Virol. 69 2869-2872.
    • (1995) J. Virol. , vol.69 , pp. 2869-2872
    • Novella, I.S.1    Elena, S.F.2    Moya, A.3    Domingo, E.4    Holland, J.J.5
  • 167
    • 0029791835 scopus 로고    scopus 로고
    • Large-population passages of vesicular stomatitis virus in interferon-treated cells select variants of only limited resistance
    • I.S. Novella, M. Cilnis, S.F. Elena, J. Kohn, A. Moya, E. Domingo and J.J. Holland (1996) Large-population passages of vesicular stomatitis virus in interferon-treated cells select variants of only limited resistance. J. Virol. 70 6414-6417.
    • (1996) J. Virol. , vol.70 , pp. 6414-6417
    • Novella, I.S.1    Cilnis, M.2    Elena, S.F.3    Kohn, J.4    Moya, A.5    Domingo, E.6    Holland, J.J.7
  • 168
    • 0033515583 scopus 로고    scopus 로고
    • Lack of evolutionary stasis during alternating replication of an arbovirus in insect and mammalian cells
    • I.S. Novella, C.L. Hershey, C. Escarmis, E. Domingo and J.J. Holland (1999) Lack of evolutionary stasis during alternating replication of an arbovirus in insect and mammalian cells. J. Mol. Biol. 287 459-465.
    • (1999) J. Mol. Biol. , vol.287 , pp. 459-465
    • Novella, I.S.1    Hershey, C.L.2    Escarmis, C.3    Domingo, E.4    Holland, J.J.5
  • 169
    • 0032902001 scopus 로고    scopus 로고
    • Exponential fitness gains of RNA virus populations are limited by bottleneck effects
    • I.S. Novella, J. Quer, E. Domingo and J.J. Holland (1999) Exponential fitness gains of RNA virus populations are limited by bottleneck effects. J. Virol. 73 1668-1671.
    • (1999) J. Virol. , vol.73 , pp. 1668-1671
    • Novella, I.S.1    Quer, J.2    Domingo, E.3    Holland, J.J.4
  • 170
    • 34249933505 scopus 로고    scopus 로고
    • Emergence of mammalian cell-adapted vesicular stomatitis virus from persistent infections of insect vector cells
    • I.S. Novella, B.E. Ebendick-Corpus, S. Zarate and E.L. Miller (2007) Emergence of mammalian cell-adapted vesicular stomatitis virus from persistent infections of insect vector cells. J. Virol. 81 6664-6668.
    • (2007) J. Virol. , vol.81 , pp. 6664-6668
    • Novella, I.S.1    Ebendick-Corpus, B.E.2    Zarate, S.3    Miller, E.L.4
  • 171
    • 33748433737 scopus 로고    scopus 로고
    • Cambridge, MA and London: The Belknap Press of Harvard University Press
    • M.A. Nowak (2006) Evolutionary Dynamics. Cambridge, MA and London: The Belknap Press of Harvard University Press
    • (2006) Evolutionary Dynamics
    • Nowak, M.A.1
  • 173
    • 0024974481 scopus 로고
    • Error thresholds of replication in finite populations mutation frequencies and the onset of Muller's ratchet
    • M. Nowak and P. Schuster (1989) Error thresholds of replication in finite populations mutation frequencies and the onset of Muller's ratchet. J. Theor. Biol. 137 375-395.
    • (1989) J. Theor. Biol. , vol.137 , pp. 375-395
    • Nowak, M.1    Schuster, P.2
  • 174
    • 34547741532 scopus 로고    scopus 로고
    • Guinea pig-adapted foot-and-mouth disease virus with altered receptor recognition can productively infect a natural host
    • J.I. Nuñez, N. Molina, E. Baranowski, E. Domingo, S. Clark, A. Burman, et al. (2007) Guinea pig-adapted foot-and-mouth disease virus with altered receptor recognition can productively infect a natural host. J. Virol. 81 8497-8506.
    • (2007) J. Virol. , vol.81 , pp. 8497-8506
    • Nuñez, J.I.1    Molina, N.2    Baranowski, E.3    Domingo, E.4    Clark, S.5    Burman, A.6
  • 175
    • 73649150958 scopus 로고
    • The maintenance of the accuracy of protein synthesis and its relevance to ageing
    • L.E. Orgel (1963) The maintenance of the accuracy of protein synthesis and its relevance to ageing. Proc. Natl Acad. Sci. USA 49 517-521.
    • (1963) Proc. Natl Acad. Sci. USA , vol.49 , pp. 517-521
    • Orgel, L.E.1
  • 176
    • 0034813056 scopus 로고    scopus 로고
    • Efficient virus extinction by combinations of a mutagen and antiviral inhibitors
    • N. Pariente, S. Sierra, P.R. Lowenstein and E. Domingo (2001) Efficient virus extinction by combinations of a mutagen and antiviral inhibitors. J. Virol. 75 9723-9730.
    • (2001) J. Virol. , vol.75 , pp. 9723-9730
    • Pariente, N.1    Sierra, S.2    Lowenstein, P.R.3    Domingo, E.4
  • 177
    • 0038278911 scopus 로고    scopus 로고
    • Mutagenesis versus inhibition in the efficiency of extinction of foot-and-mouth disease virus
    • N. Pariente, A. Airaksinen and E. Domingo (2003) Mutagenesis versus inhibition in the efficiency of extinction of foot-and-mouth disease virus. J. Virol. 77 7131-7138.
    • (2003) J. Virol. , vol.77 , pp. 7131-7138
    • Pariente, N.1    Airaksinen, A.2    Domingo, E.3
  • 178
    • 27144453692 scopus 로고    scopus 로고
    • The origins of new pandemic viruses: the acquisition of new host ranges by canine parvovirus and influenza A viruses
    • C.R. Parrish and Y. Kawaoka (2005) The origins of new pandemic viruses: the acquisition of new host ranges by canine parvovirus and influenza A viruses. Annu. Rev. Microbiol. 59 553-586.
    • (2005) Annu. Rev. Microbiol. , vol.59 , pp. 553-586
    • Parrish, C.R.1    Kawaoka, Y.2
  • 179
    • 0026528541 scopus 로고
    • 5-Azacytidine and RNA secondary structure increase the retrovirus mutation rate
    • V.K. Pathak and H.M. Temin (1992) 5-Azacytidine and RNA secondary structure increase the retrovirus mutation rate. J. Virol. 66 3093-3100.
    • (1992) J. Virol. , vol.66 , pp. 3093-3100
    • Pathak, V.K.1    Temin, H.M.2
  • 180
    • 0031923838 scopus 로고    scopus 로고
    • Interferon resistance of hepatitis C virus genotype 1b: relationship to nonstructural 5A gene quasispecies mutations
    • J.M. Pawlotsky, G. Germanidis, A.U. Neumann, M. Pellerin, P.O. Frainais and D. Dhumeaux (1998) Interferon resistance of hepatitis C virus genotype 1b: relationship to nonstructural 5A gene quasispecies mutations. J. Virol. 72 2795-2805.
    • (1998) J. Virol. , vol.72 , pp. 2795-2805
    • Pawlotsky, J.M.1    Germanidis, G.2    Neumann, A.U.3    Pellerin, M.4    Frainais, P.O.5    Dhumeaux, D.6
  • 181
    • 0015187190 scopus 로고
    • Growth of viruses in arthropod cell cultures: applications. I. Attenuation of Semliki Forest (SF) virus in continuously cultured Aedes aegypti mosquito cells (Peleg) as a step in production of vaccines
    • J. Peleg (1971) Growth of viruses in arthropod cell cultures: applications. I. Attenuation of Semliki Forest (SF) virus in continuously cultured Aedes aegypti mosquito cells (Peleg) as a step in production of vaccines. Curr. Top. Microbiol. Immunol. 55 155-161.
    • (1971) Curr. Top. Microbiol. Immunol. , vol.55 , pp. 155-161
    • Peleg, J.1
  • 182
    • 0035261907 scopus 로고    scopus 로고
    • Site-directed mutagenesis of human immunodeficiency virus type 1 reverse transcriptase at amino acid position 138
    • H. Pelemans, A. Aertsen, K. Van Laethem, A.M. Vandamme, E. De Clercq, M.J. Perez-Perez, et al. (2001) Site-directed mutagenesis of human immunodeficiency virus type 1 reverse transcriptase at amino acid position 138. Virology 280 97-106.
    • (2001) Virology , vol.280 , pp. 97-106
    • Pelemans, H.1    Aertsen, A.2    Van Laethem, K.3    Vandamme, A.M.4    De Clercq, E.5    Perez-Perez, M.J.6
  • 183
    • 34248577724 scopus 로고    scopus 로고
    • Insights into RNA virus mutant spectrum and lethal mutagenesis events: replicative interference and complementation by multiple point mutants
    • C. Perales, R. Mateo, M.G. Mateu and E. Domingo (2007) Insights into RNA virus mutant spectrum and lethal mutagenesis events: replicative interference and complementation by multiple point mutants. J. Mol. Biol. 369 985-1000.
    • (2007) J. Mol. Biol. , vol.369 , pp. 985-1000
    • Perales, C.1    Mateo, R.2    Mateu, M.G.3    Domingo, E.4
  • 184
    • 34247607729 scopus 로고    scopus 로고
    • Ribavirin: is it a mutagen for hepatitis C virus?
    • A.S. Perelson and T.J. Layden (2007) Ribavirin: is it a mutagen for hepatitis C virus? Gastroenterology 132 2050-2052.
    • (2007) Gastroenterology , vol.132 , pp. 2050-2052
    • Perelson, A.S.1    Layden, T.J.2
  • 185
    • 38349007013 scopus 로고    scopus 로고
    • 5th edn, Philadelphia: Lippincott Williams and Wilkins, pp. 605–625
    • C.J. Peters (2007) Emerging Viral Diseases. 5th edn Philadelphia: Lippincott Williams and Wilkins pp. 605–625.
    • (2007) Emerging Viral Diseases
    • Peters, C.J.1
  • 186
    • 0036784575 scopus 로고    scopus 로고
    • Replacement of the P1 amino acid of human immunodeficiency virus type 1 Gag processing sites can inhibit or enhance the rate of cleavage by the viral protease
    • S.C. Pettit, G.J. Henderson, C.A. Schiffer and R. Swanstrom (2002) Replacement of the P1 amino acid of human immunodeficiency virus type 1 Gag processing sites can inhibit or enhance the rate of cleavage by the viral protease. J. Virol. 76 10226-10233.
    • (2002) J. Virol. , vol.76 , pp. 10226-10233
    • Pettit, S.C.1    Henderson, G.J.2    Schiffer, C.A.3    Swanstrom, R.4
  • 187
    • 0038809107 scopus 로고    scopus 로고
    • A single mutation in poliovirus RNA-dependent RNA polymerase confers resistance to mutagenic nucleotide analogs via increased fidelity
    • J.K. Pfeiffer and K. Kirkegaard (2003) A single mutation in poliovirus RNA-dependent RNA polymerase confers resistance to mutagenic nucleotide analogs via increased fidelity. Proc. Natl Acad. Sci. USA 100 7289-7294.
    • (2003) Proc. Natl Acad. Sci. USA , vol.100 , pp. 7289-7294
    • Pfeiffer, J.K.1    Kirkegaard, K.2
  • 188
    • 33745490138 scopus 로고    scopus 로고
    • Increased fidelity reduces poliovirus fitness under selective pressure in mice
    • J.K. Pfeiffer and K. Kirkegaard (2005) Increased fidelity reduces poliovirus fitness under selective pressure in mice. PLoS Pathog. 1 102-110.
    • (2005) PLoS Pathog. , vol.1 , pp. 102-110
    • Pfeiffer, J.K.1    Kirkegaard, K.2
  • 189
    • 33645758779 scopus 로고    scopus 로고
    • Bottleneck-mediated quasispecies restriction during spread of an RNA virus from inoculation site to brain
    • J.K. Pfeiffer and K. Kirkegaard (2006) Bottleneck-mediated quasispecies restriction during spread of an RNA virus from inoculation site to brain. Proc. Natl Acad. Sci. USA 103 5520-5525.
    • (2006) Proc. Natl Acad. Sci. USA , vol.103 , pp. 5520-5525
    • Pfeiffer, J.K.1    Kirkegaard, K.2
  • 190
    • 0037012979 scopus 로고    scopus 로고
    • Amprenavir-resistant HIV-1 exhibits lopinavir cross-resistance and reduced replication capacity
    • J.G. Prado, T. Wrin, J. Beauchaine, L. Ruiz, C.J. Petropoulos, S.D. Frost, et al. (2002) Amprenavir-resistant HIV-1 exhibits lopinavir cross-resistance and reduced replication capacity. Aids 16 1009-1017.
    • (2002) Aids , vol.16 , pp. 1009-1017
    • Prado, J.G.1    Wrin, T.2    Beauchaine, J.3    Ruiz, L.4    Petropoulos, C.J.5    Frost, S.D.6
  • 192
    • 0036786425 scopus 로고    scopus 로고
    • Insertions in the reverse transcriptase increase both drug resistance and viral fitness in a human immunodeficiency virus type 1 isolate harboring the multi-nucleoside reverse transcriptase inhibitor resistance 69 insertion complex mutation
    • M.E. Quiñones-Mateu, M. Tadele, M. Parera, A. Mas, J. Weber, H.R. Rangel, et al. (2002) Insertions in the reverse transcriptase increase both drug resistance and viral fitness in a human immunodeficiency virus type 1 isolate harboring the multi-nucleoside reverse transcriptase inhibitor resistance 69 insertion complex mutation. J. Virol. 76 10546-10552.
    • (2002) J. Virol. , vol.76 , pp. 10546-10552
    • Quiñones-Mateu, M.E.1    Tadele, M.2    Parera, M.3    Mas, A.4    Weber, J.5    Rangel, H.R.6
  • 193
    • 30644462096 scopus 로고    scopus 로고
    • Virus fitness: concept, qunatification and application to HIV population dynamics
    • M.E. Quiñones-Mateu and E. Arts (2006) Virus fitness: concept, qunatification and application to HIV population dynamics. Curr. Top. Microbiol. Immunol. 299 83-140.
    • (2006) Curr. Top. Microbiol. Immunol. , vol.299 , pp. 83-140
    • Quiñones-Mateu, M.E.1    Arts, E.2
  • 194
    • 0037059049 scopus 로고    scopus 로고
    • Sensitivity of HIV-1 to entry inhibitors correlates with envelope/coreceptor affinity, receptor density and fusion kinetics
    • J.D. Reeves, S.A. Gallo, N. Ahmad, J.L. Miamidian, P.E. Harvey, M. Sharron, et al. (2002) Sensitivity of HIV-1 to entry inhibitors correlates with envelope/coreceptor affinity, receptor density and fusion kinetics. Proc. Natl Acad. Sci. U S A 99 16249-16254.
    • (2002) Proc. Natl Acad. Sci. U S A , vol.99 , pp. 16249-16254
    • Reeves, J.D.1    Gallo, S.A.2    Ahmad, N.3    Miamidian, J.L.4    Harvey, P.E.5    Sharron, M.6
  • 195
    • 16244380203 scopus 로고    scopus 로고
    • Enfuvirtide resistance mutations: impact on human immunodeficiency virus envelope function, entry inhibitor sensitivity and virus neutralization
    • J.D. Reeves, F.H. Lee, J.L. Miamidian, C.B. Jabara, M.M. Juntilla and R.W. Doms (2005) Enfuvirtide resistance mutations: impact on human immunodeficiency virus envelope function, entry inhibitor sensitivity and virus neutralization. J. Virol. 79 4991-4999.
    • (2005) J. Virol. , vol.79 , pp. 4991-4999
    • Reeves, J.D.1    Lee, F.H.2    Miamidian, J.L.3    Jabara, C.B.4    Juntilla, M.M.5    Doms, R.W.6
  • 196
    • 0002846255 scopus 로고    scopus 로고
    • The empirical study of adaptation in natural populations
    • M.R. Rose, G.V. Lander (Eds), San Diego: Academic Press
    • D. Reznick and J. Travis (1996) The empirical study of adaptation in natural populations. M.R. Rose, G.V. Lander (Eds) Adaptation San Diego: Academic Press 243-289.
    • (1996) Adaptation , pp. 243-289
    • Reznick, D.1    Travis, J.2
  • 197
    • 0031883832 scopus 로고    scopus 로고
    • Determinants of human immunodeficiency virus type 1 resistance to gp41-derived inhibitory peptides
    • L.T. Rimsky, D.C. Shugars and T.J. Matthews (1998) Determinants of human immunodeficiency virus type 1 resistance to gp41-derived inhibitory peptides. J. Virol. 72 986-993.
    • (1998) J. Virol. , vol.72 , pp. 986-993
    • Rimsky, L.T.1    Shugars, D.C.2    Matthews, T.J.3
  • 198
    • 0026631017 scopus 로고
    • Genetic relatedness of hepatitis A virus strains recovered from different geographical regions
    • B.H. Robertson, R.W. Jansen, B. Khanna, A. Totsuka, O.V. Nainan, G. Siegl, et al. (1992) Genetic relatedness of hepatitis A virus strains recovered from different geographical regions. J. Gen. Virol. 73 1365-1377.
    • (1992) J. Gen. Virol. , vol.73 , pp. 1365-1377
    • Robertson, B.H.1    Jansen, R.W.2    Khanna, B.3    Totsuka, A.4    Nainan, O.V.5    Siegl, G.6
  • 199
    • 0025983849 scopus 로고
    • Effects of defective interfering viruses on virus replication and pathogenesis in vitro and in vivo
    • L. Roux, A.E. Simon and J.J. Holland (1991) Effects of defective interfering viruses on virus replication and pathogenesis in vitro and in vivo. Adv. Virus Res. 40 181-211.
    • (1991) Adv. Virus Res. , vol.40 , pp. 181-211
    • Roux, L.1    Simon, A.E.2    Holland, J.J.3
  • 202
    • 0345578679 scopus 로고    scopus 로고
    • Lethal mutagenesis of the prototypic arenavirus lymphocytic choriomeningitis virus (LCMV)
    • C.M. Ruiz-Jarabo, C. Ly, E. Domingo and J.C. de la Torre (2003) Lethal mutagenesis of the prototypic arenavirus lymphocytic choriomeningitis virus (LCMV). Virology 308 37-47.
    • (2003) Virology , vol.308 , pp. 37-47
    • Ruiz-Jarabo, C.M.1    Ly, C.2    Domingo, E.3    de la Torre, J.C.4
  • 203
    • 0141862176 scopus 로고    scopus 로고
    • Synchronous loss of quasispecies memory in parallel viral lineages: a deterministic feature of viral quasispecies
    • C.M. Ruiz-Jarabo, E. Miller, G. Gómez-Mariano and E. Domingo (2003) Synchronous loss of quasispecies memory in parallel viral lineages: a deterministic feature of viral quasispecies. J. Mol. Biol. 333 553-563.
    • (2003) J. Mol. Biol. , vol.333 , pp. 553-563
    • Ruiz-Jarabo, C.M.1    Miller, E.2    Gómez-Mariano, G.3    Domingo, E.4
  • 204
    • 33645510409 scopus 로고    scopus 로고
    • Exact solution of the Eigen model with general fitness functions and degradation rates
    • D.B. Saakian and C.K. Hu (2006) Exact solution of the Eigen model with general fitness functions and degradation rates. Proc. Natl Acad. Sci. USA, 103 4935-4939.
    • (2006) Proc. Natl Acad. Sci. USA , vol.103 , pp. 4935-4939
    • Saakian, D.B.1    Hu, C.K.2
  • 207
    • 19244363136 scopus 로고    scopus 로고
    • Multiple drug resistance to nucleoside analogues and nonnucleoside reverse transcriptase inhibitors in an efficiently replicating human immunodeficiency virus type 1 patient strain
    • J.C. Schmit, J. Cogniaux, P. Hermans, C. Van Vaeck, S. Sprecher, B. Van Remoortel, et al. (1996) Multiple drug resistance to nucleoside analogues and nonnucleoside reverse transcriptase inhibitors in an efficiently replicating human immunodeficiency virus type 1 patient strain. J. Infect. Dis. 174 962-968.
    • (1996) J. Infect. Dis. , vol.174 , pp. 962-968
    • Schmit, J.C.1    Cogniaux, J.2    Hermans, P.3    Van Vaeck, C.4    Sprecher, S.5    Van Remoortel, B.6
  • 208
    • 0029731556 scopus 로고    scopus 로고
    • Mutational anatomy of an HIV-1 protease variant conferring cross-resistance to protease inhibitors in clinical trials. Compensatory modulations of binding and activity
    • H.B. Schock, V.M. Garsky and L.C. Kuo (1996) Mutational anatomy of an HIV-1 protease variant conferring cross-resistance to protease inhibitors in clinical trials. Compensatory modulations of binding and activity. J. Biol. Chem. 271 31957-31963.
    • (1996) J. Biol. Chem. , vol.271 , pp. 31957-31963
    • Schock, H.B.1    Garsky, V.M.2    Kuo, L.C.3
  • 210
    • 0032103187 scopus 로고    scopus 로고
    • Multiple concurrent reverse transcriptase and protease mutations and multidrug resistance of HIV-1 isolates from heavily treated patients
    • R.W. Shafer, M.A. Winters, S. Palmer and T.C. Merigan (1998) Multiple concurrent reverse transcriptase and protease mutations and multidrug resistance of HIV-1 isolates from heavily treated patients. Ann. Intern. Med. 128 906-911.
    • (1998) Ann. Intern. Med. , vol.128 , pp. 906-911
    • Shafer, R.W.1    Winters, M.A.2    Palmer, S.3    Merigan, T.C.4
  • 211
    • 0030768138 scopus 로고    scopus 로고
    • Attenuated replication of human immunodeficiency virus type 1 with a didanosine-selected reverse transcriptase mutation
    • P.L. Sharma and C.S. Crumpacker (1997) Attenuated replication of human immunodeficiency virus type 1 with a didanosine-selected reverse transcriptase mutation. J. Virol. 71 8846-88451.
    • (1997) J. Virol. , vol.71 , pp. 8846-88451
    • Sharma, P.L.1    Crumpacker, C.S.2
  • 212
    • 0032875344 scopus 로고    scopus 로고
    • Decreased processivity of human immunodeficiency virus type 1 reverse transcriptase (RT) containing didanosine-selected mutation Leu74Val: a comparative analysis of RT variants Leu74Val and lamivudine-selected Met184Val
    • P.L. Sharma and C.S. Crumpacker (1999) Decreased processivity of human immunodeficiency virus type 1 reverse transcriptase (RT) containing didanosine-selected mutation Leu74Val: a comparative analysis of RT variants Leu74Val and lamivudine-selected Met184Val. J. Virol. 73 8448-8456.
    • (1999) J. Virol. , vol.73 , pp. 8448-8456
    • Sharma, P.L.1    Crumpacker, C.S.2
  • 213
    • 0028940084 scopus 로고
    • Emergence of human immunodeficiency virus type 1 variants with resistance to multiple dideoxynucleosides in patients receiving therapy with dideoxynucleosides
    • T. Shirasaka, M.F. Kavlick, T. Ueno, W.Y. Gao, E. Kojima, M.L. Alcaide, et al. (1995) Emergence of human immunodeficiency virus type 1 variants with resistance to multiple dideoxynucleosides in patients receiving therapy with dideoxynucleosides. Proc. Natl Acad. Sci. USA, 92 2398-2402.
    • (1995) Proc. Natl Acad. Sci. USA , vol.92 , pp. 2398-2402
    • Shirasaka, T.1    Kavlick, M.F.2    Ueno, T.3    Gao, W.Y.4    Kojima, E.5    Alcaide, M.L.6
  • 214
    • 33846813925 scopus 로고    scopus 로고
    • Foot-and-mouth disease virus mutant with decreased sensitivity to ribavirin: implications for error catastrophe
    • M. Sierra, A. Airaksinen, C. González-López, R. Agudo, A. Arias and E. Domingo (2007) Foot-and-mouth disease virus mutant with decreased sensitivity to ribavirin: implications for error catastrophe. J. Virol. 81 2012-2024.
    • (2007) J. Virol. , vol.81 , pp. 2012-2024
    • Sierra, M.1    Airaksinen, A.2    González-López, C.3    Agudo, R.4    Arias, A.5    Domingo, E.6
  • 218
    • 0027064537 scopus 로고
    • Lack of evidence for proofreading mechanisms associated with an RNA virus polymerase
    • D.A. Steinhauer, E. Domingo and J.J. Holland (1992) Lack of evidence for proofreading mechanisms associated with an RNA virus polymerase. Gene 122 281-288.
    • (1992) Gene , vol.122 , pp. 281-288
    • Steinhauer, D.A.1    Domingo, E.2    Holland, J.J.3
  • 219
    • 21144441367 scopus 로고    scopus 로고
    • Sialobiology of influenza: molecular mechanism of host range variation of influenza viruses
    • Y. Suzuki (2005) Sialobiology of influenza: molecular mechanism of host range variation of influenza viruses. Biol. Pharm. Bull. 28 399-408.
    • (2005) Biol. Pharm. Bull. , vol.28 , pp. 399-408
    • Suzuki, Y.1
  • 220
    • 84961572401 scopus 로고
    • Self-replication with errors. A model for polynucleotide replication
    • J. Swetina and P. Schuster (1982) Self-replication with errors. A model for polynucleotide replication. Biophys. Chem. 16 329-345.
    • (1982) Biophys. Chem. , vol.16 , pp. 329-345
    • Swetina, J.1    Schuster, P.2
  • 221
    • 20644470543 scopus 로고    scopus 로고
    • Combination of a mutagenic agent with a reverse transcriptase inhibitor results in systematic inhibition of HIV-1 infection
    • N. Tapia, G. Fernandez, M. Parera, G. Gomez-Mariano, B. Clotet, M. Quiñones-Mateu, et al. (2005) Combination of a mutagenic agent with a reverse transcriptase inhibitor results in systematic inhibition of HIV-1 infection. Virology 338 1-8.
    • (2005) Virology , vol.338 , pp. 1-8
    • Tapia, N.1    Fernandez, G.2    Parera, M.3    Gomez-Mariano, G.4    Clotet, B.5    Quiñones-Mateu, M.6
  • 222
    • 0024516413 scopus 로고
    • Is HIV unique or merely different?
    • H.M. Temin (1989) Is HIV unique or merely different? J. AIDS 2 1-9.
    • (1989) J. AIDS , vol.2 , pp. 1-9
    • Temin, H.M.1
  • 223
    • 0001771126 scopus 로고
    • The high rate of retrovirus variation results in rapid evolution
    • S.S. Morse (Eds), Oxford: Oxford University Press
    • H.M. Temin (1993) The high rate of retrovirus variation results in rapid evolution. S.S. Morse (Eds) Emerging Viruses Oxford: Oxford University Press 219-225.
    • (1993) Emerging Viruses , pp. 219-225
    • Temin, H.M.1
  • 224
    • 0030247470 scopus 로고    scopus 로고
    • Suppression of lymphocytic choriomeningitis virus-induced growth hormone deficiency syndrome by disease-negative virus variants
    • M.N. Teng, M.B. Oldstone and J.C. de la Torre (1996) Suppression of lymphocytic choriomeningitis virus-induced growth hormone deficiency syndrome by disease-negative virus variants. Virology 223 113-119.
    • (1996) Virology , vol.223 , pp. 113-119
    • Teng, M.N.1    Oldstone, M.B.2    de la Torre, J.C.3
  • 225
    • 0002027029 scopus 로고
    • A new evolutionary law
    • L. Van Valen (1973) A new evolutionary law. Evol. Theory 1 1-30.
    • (1973) Evol. Theory , vol.1 , pp. 1-30
    • Van Valen, L.1
  • 226
    • 31144465690 scopus 로고    scopus 로고
    • Quasispecies diversity determines pathogenesis through cooperative interactions in a viral population
    • M. Vignuzzi, J.K. Stone, J.J. Arnold, C.E. Cameron and R. Andino (2006) Quasispecies diversity determines pathogenesis through cooperative interactions in a viral population. Nature 439 344-348.
    • (2006) Nature , vol.439 , pp. 344-348
    • Vignuzzi, M.1    Stone, J.K.2    Arnold, J.J.3    Cameron, C.E.4    Andino, R.5
  • 228
    • 33646237789 scopus 로고    scopus 로고
    • The HIV-1 reverse transcriptase mutants G190S and G190A, which confer resistance to non-nucleoside reverse transcriptase inhibitors, demonstrate reductions in RNase H activity and DNA synthesis from tRNA(Lys, 3) that correlate with reductions in replication efficiency
    • J. Wang, C. Dykes, R.A. Domaoal, C.E. Koval, R.A. Bambara and L.M. Demeter (2006) The HIV-1 reverse transcriptase mutants G190S and G190A, which confer resistance to non-nucleoside reverse transcriptase inhibitors, demonstrate reductions in RNase H activity and DNA synthesis from tRNA(Lys, 3) that correlate with reductions in replication efficiency. Virology 348 462-474.
    • (2006) Virology , vol.348 , pp. 462-474
    • Wang, J.1    Dykes, C.2    Domaoal, R.A.3    Koval, C.E.4    Bambara, R.A.5    Demeter, L.M.6
  • 229
    • 0002083353 scopus 로고    scopus 로고
    • Recurrent emergence of Venezuelan equine encephalomyelitis
    • W.M. Sheld, J. Hughes (Eds), Washington DC: ASM Press
    • S.C. Weaver (1998) Recurrent emergence of Venezuelan equine encephalomyelitis. W.M. Sheld, J. Hughes (Eds) Emerging Infections Vol. 1 Washington DC: ASM Press 27-42.
    • (1998) Emerging Infections , vol.1 , pp. 27-42
    • Weaver, S.C.1
  • 230
    • 84987266075 scopus 로고
    • A statistical distribution function of wide applicability
    • W.J. Weibull (1951) A statistical distribution function of wide applicability. Appl. Mech. 18 293-297.
    • (1951) Appl. Mech. , vol.18 , pp. 293-297
    • Weibull, W.J.1
  • 231
    • 33847237614 scopus 로고    scopus 로고
    • Reduced maximal inhibition in phenotypic susceptibility assays indicates that viral strains resistant to the CCR5 antagonist maraviroc utilize inhibitor-bound receptor for entry
    • M. Westby, C. Smith-Burchnell, J. Mori, M. Lewis, M. Mosley, M. Stockdale, et al. (2007) Reduced maximal inhibition in phenotypic susceptibility assays indicates that viral strains resistant to the CCR5 antagonist maraviroc utilize inhibitor-bound receptor for entry. J. Virol. 81 2359-2371.
    • (2007) J. Virol. , vol.81 , pp. 2359-2371
    • Westby, M.1    Smith-Burchnell, C.2    Mori, J.3    Lewis, M.4    Mosley, M.5    Stockdale, M.6
  • 232
    • 0036839746 scopus 로고    scopus 로고
    • Molecular mechanisms of resistance to human immunodeficiency virus type 1 with reverse transcriptase mutations K65R and K65R+M184V and their effects on enzyme function and viral replication capacity
    • K.L. White, N.A. Margot, T. Wrin, C.J. Petropoulos, M.D. Miller and L.K. Naeger (2002) Molecular mechanisms of resistance to human immunodeficiency virus type 1 with reverse transcriptase mutations K65R and K65R+M184V and their effects on enzyme function and viral replication capacity. Antimicrob. Agents Chemother 46 3437-3446.
    • (2002) Antimicrob. Agents Chemother , vol.46 , pp. 3437-3446
    • White, K.L.1    Margot, N.A.2    Wrin, T.3    Petropoulos, C.J.4    Miller, M.D.5    Naeger, L.K.6
  • 233
    • 2942549839 scopus 로고    scopus 로고
    • Phenotypic mixing and hiding may contribute to memory in viral quasispecies
    • C.O. Wilke and I..S. Novella (2003) Phenotypic mixing and hiding may contribute to memory in viral quasispecies. BMC Microbiol. 3 11.
    • (2003) BMC Microbiol. , vol.3 , pp. 11
    • Wilke, C.O.1    Novella, I.S.2
  • 234
    • 0035430003 scopus 로고    scopus 로고
    • Dynamic fitness landscapes in molecular evolution
    • C.O. Wilke, C. Ronnewinkel and T. Martinetz (2001) Dynamic fitness landscapes in molecular evolution. Phys. Rep. 349 395-446.
    • (2001) Phys. Rep. , vol.349 , pp. 395-446
    • Wilke, C.O.1    Ronnewinkel, C.2    Martinetz, T.3
  • 235
    • 0035913336 scopus 로고    scopus 로고
    • Evolution of digital organisms at high mutation rates leads to survival of the flattest
    • C.O. Wilke, J.L. Wang, C. Ofria, R.E. Lenski and C. Adami (2001) Evolution of digital organisms at high mutation rates leads to survival of the flattest. Nature 412 331-333.
    • (2001) Nature , vol.412 , pp. 331-333
    • Wilke, C.O.1    Wang, J.L.2    Ofria, C.3    Lenski, R.E.4    Adami, C.5
  • 236
    • 0346922470 scopus 로고    scopus 로고
    • Replication at periodically changing multiplicity of infection promotes stable coexistence of competing viral populations
    • C.O. Wilke, D.D. Reissig and I..S. Novella (2004) Replication at periodically changing multiplicity of infection promotes stable coexistence of competing viral populations. Evolution Int. J. Org. Evolution, 58 900-905.
    • (2004) Evolution Int. J. Org. Evolution , vol.58 , pp. 900-905
    • Wilke, C.O.1    Reissig, D.D.2    Novella, I.S.3
  • 239
    • 0031804609 scopus 로고    scopus 로고
    • Inhibitors of HIV-1 protease: a major success of structure-assisted drug design
    • A. Wlodawer and J. Vondrasek (1998) Inhibitors of HIV-1 protease: a major success of structure-assisted drug design. Annu. Rev. Biophys. Biomol. Struct. 27 249-284.
    • (1998) Annu. Rev. Biophys. Biomol. Struct. , vol.27 , pp. 249-284
    • Wlodawer, A.1    Vondrasek, J.2
  • 240
    • 34547776050 scopus 로고    scopus 로고
    • Orthomyxoviruses
    • D.M. Dnipe, P.M. Howley, et al., (Eds), 5th edn, Philadelphia: Lippincott Williams & Wilkins
    • P.F. Wright, G. Neumann, Y. Kawaoka (2007) Orthomyxoviruses. D.M. Dnipe, P.M. Howley, et al., (Eds) Fields Virology 5th edn Philadelphia: Lippincott Williams & Wilkins 1691-1740.
    • (2007) Fields Virology , pp. 1691-1740
    • Wright, P.F.1    Neumann, G.2    Kawaoka, Y.3
  • 241
    • 0031936597 scopus 로고    scopus 로고
    • Immunity in chimpanzees chronically infected with hepatitis C virus: role of minor quasispecies in reinfection
    • C.A. Wyatt, L. Andrus, B. Brotman, F. Huang, D.H. Lee and A.M. Prince (1998) Immunity in chimpanzees chronically infected with hepatitis C virus: role of minor quasispecies in reinfection. J. Virol. 72 1725-1730.
    • (1998) J. Virol. , vol.72 , pp. 1725-1730
    • Wyatt, C.A.1    Andrus, L.2    Brotman, B.3    Huang, F.4    Lee, D.H.5    Prince, A.M.6
  • 243
  • 244
    • 0031977656 scopus 로고    scopus 로고
    • Switch to unusual amino acids at codon 215 of the human immunodeficiency virus type 1 reverse transcriptase gene in seroconvertors infected with zidovudine-resistant variants
    • S. Yerly, A. Rakik, S.K. De Loes, B. Hirschel, D. Descamps, F. Brun-Vezinet and L. Perrin (1998) Switch to unusual amino acids at codon 215 of the human immunodeficiency virus type 1 reverse transcriptase gene in seroconvertors infected with zidovudine-resistant variants. J. Virol. 72 3520-3523.
    • (1998) J. Virol. , vol.72 , pp. 3520-3523
    • Yerly, S.1    Rakik, A.2    De Loes, S.K.3    Hirschel, B.4    Descamps, D.5    Brun-Vezinet, F.6    Perrin, L.7
  • 245
    • 0036188268 scopus 로고    scopus 로고
    • Construction of a human immunodeficiency virus type 1 (HIV-1) library containing random combinations of amino acid substitutions in the HIV-1 protease due to resistance by protease inhibitors
    • K. Yusa, W. Song, M. Bartelmann and S. Harada (2002) Construction of a human immunodeficiency virus type 1 (HIV-1) library containing random combinations of amino acid substitutions in the HIV-1 protease due to resistance by protease inhibitors. J. Virol. 76 3031-3037.
    • (2002) J. Virol. , vol.76 , pp. 3031-3037
    • Yusa, K.1    Song, W.2    Bartelmann, M.3    Harada, S.4
  • 246
    • 0345471842 scopus 로고    scopus 로고
    • Drastic fitness loss in human immunodeficiency virus type 1 upon serial bottleneck events
    • E. Yuste, S. Sánchez-Palomino, C. Casado, E. Domingo and C. López-Galíndez (1999) Drastic fitness loss in human immunodeficiency virus type 1 upon serial bottleneck events. J. Virol. 73 2745-2751.
    • (1999) J. Virol. , vol.73 , pp. 2745-2751
    • Yuste, E.1    Sánchez-Palomino, S.2    Casado, C.3    Domingo, E.4    López-Galíndez, C.5
  • 247
    • 4444342618 scopus 로고    scopus 로고
    • Vesicular stomatitis virus evolution during alternation between persistent infection in insect cells and acute infection in mammalian cells is dominated by the persistence phase
    • S. Zárate and I..S. Novella (2004) Vesicular stomatitis virus evolution during alternation between persistent infection in insect cells and acute infection in mammalian cells is dominated by the persistence phase. J. Virol. 78 12236-12242.
    • (2004) J. Virol. , vol.78 , pp. 12236-12242
    • Zárate, S.1    Novella, I.S.2
  • 248
    • 0030974504 scopus 로고    scopus 로고
    • Genotypic and phenotypic characterization of long terminal repeat sequences from long-term survivors of human immunodeficiency virus type 1 infection
    • L. Zhang, Y. Huang, H. Yuan, B.K. Chen, J. Ip and D.D. Ho (1997) Genotypic and phenotypic characterization of long terminal repeat sequences from long-term survivors of human immunodeficiency virus type 1 infection. J. Virol. 71 5608-5613.
    • (1997) J. Virol. , vol.71 , pp. 5608-5613
    • Zhang, L.1    Huang, Y.2    Yuan, H.3    Chen, B.K.4    Ip, J.5    Ho, D.D.6
  • 249
    • 34247599746 scopus 로고    scopus 로고
    • Quasispecies of bovine enteric and respiratory coronaviruses based on complete genome sequences and genetic changes after tissue culture adaptation
    • X. Zhang, M. Hasoksuz, D. Spiro, R. Halpin, S. Wang, A. Vlasova, et al. (2007) Quasispecies of bovine enteric and respiratory coronaviruses based on complete genome sequences and genetic changes after tissue culture adaptation. Virology 363 1-10.
    • (2007) Virology , vol.363 , pp. 1-10
    • Zhang, X.1    Hasoksuz, M.2    Spiro, D.3    Halpin, R.4    Wang, S.5    Vlasova, A.6
  • 250
    • 85053971721 scopus 로고
    • Evolution of RNA viruses
    • E. Domingo, J.J. Holland, P. Ahlquist (Eds), Florida: CRC Press Inc
    • D. Zimmern (1988) Evolution of RNA viruses. E. Domingo, J.J. Holland, P. Ahlquist (Eds) RNA Genetics Vol. 2 Florida: CRC Press Inc 211-240.
    • (1988) RNA Genetics , vol.2 , pp. 211-240
    • Zimmern, D.1


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