-
1
-
-
85033050931
-
Nonclinical toxicology studies with zidovudine: Genetic toxicity tests and carcinogenicity bioassays in mice and rats
-
K.M. Ayers, D. Clive, W.E. Tucker Jr., G. Hajian, and P. de Miranda Nonclinical toxicology studies with zidovudine: genetic toxicity tests and carcinogenicity bioassays in mice and rats Fundam. Appl. Toxicol. 32 1996 148 158
-
(1996)
Fundam. Appl. Toxicol.
, vol.32
, pp. 148-158
-
-
Ayers, K.M.1
Clive, D.2
Tucker Jr., W.E.3
Hajian, G.4
De Miranda, P.5
-
2
-
-
0034990846
-
Exploitation of the low fidelity of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase and the nucleotide composition bias in the HIV-1 genome to alter the drug resistance development of HIV
-
J. Balzarini, M.J. Camarasa, M.J. Pérez-Pérez, A. San-Félix, S. Velazquez, C.F. Perno, E. De Clercq, J.N. Anderson, and A. Karlsson Exploitation of the low fidelity of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase and the nucleotide composition bias in the HIV-1 genome to alter the drug resistance development of HIV J. Virol. 75 2001 5772 5777
-
(2001)
J. Virol.
, vol.75
, pp. 5772-5777
-
-
Balzarini, J.1
Camarasa, M.J.2
Pérez-Pérez, M.J.3
San-Félix, A.4
Velazquez, S.5
Perno, C.F.6
De Clercq, E.7
Anderson, J.N.8
Karlsson, A.9
-
3
-
-
0036174438
-
Assessment of mitochondrial toxicity in human cells treated with tenofovir: Comparison with other nucleoside reverse transcriptase inhibitors
-
G. Birkus, M.J.M. Hitchcock, and T. Cihlar Assessment of mitochondrial toxicity in human cells treated with tenofovir: comparison with other nucleoside reverse transcriptase inhibitors Antimicrob. Agents Chemother. 46 2002 716 723
-
(2002)
Antimicrob. Agents Chemother.
, vol.46
, pp. 716-723
-
-
Birkus, G.1
Hitchcock, M.J.M.2
Cihlar, T.3
-
4
-
-
0028952146
-
HIV population dynamics in vivo: Implications for genetic variation, pathogenesis, and therapy
-
J.M. Coffin HIV population dynamics in vivo: implications for genetic variation, pathogenesis, and therapy Science 267 1995 483 489
-
(1995)
Science
, vol.267
, pp. 483-489
-
-
Coffin, J.M.1
-
5
-
-
0023035969
-
Differences in DNA damage produced by incorporation of 5-aza-2′-deoxycytidine or 5,6-dihydro-5-azacytidine into DNA of mammalian cells
-
J.M. Covey, M. D'Incalci, E.J. Tilchen, D.S. Zaharko, and K.W. Kohn Differences in DNA damage produced by incorporation of 5-aza-2′- deoxycytidine or 5,6-dihydro-5-azacytidine into DNA of mammalian cells Cancer Res. 46 1986 5511 5517
-
(1986)
Cancer Res.
, vol.46
, pp. 5511-5517
-
-
Covey, J.M.1
D'Incalci, M.2
Tilchen, E.J.3
Zaharko, D.S.4
Kohn, K.W.5
-
6
-
-
0027285909
-
A phase II study of 5,6-dihydro-5-azacytidine hydrochloride in disseminated malignant melanoma
-
E.T. Creagan, D.J. Schaid, L.C. Hartmann, and C.L. Loprinzi A phase II study of 5,6-dihydro-5-azacytidine hydrochloride in disseminated malignant melanoma Am. J. Clin. Oncol. 16 1993 243 244
-
(1993)
Am. J. Clin. Oncol.
, vol.16
, pp. 243-244
-
-
Creagan, E.T.1
Schaid, D.J.2
Hartmann, L.C.3
Loprinzi, C.L.4
-
7
-
-
0034532953
-
The broad-spectrum antiviral ribonucleoside ribavirin is an RNA virus mutagen
-
S. Crotty, D. Maag, J.J. Arnold, W. Zhong, J.Y. Lau, Z. Hong, R. Andino, and C.E. Cameron The broad-spectrum antiviral ribonucleoside ribavirin is an RNA virus mutagen Nat. Med. 6 2000 1375 1379
-
(2000)
Nat. Med.
, vol.6
, pp. 1375-1379
-
-
Crotty, S.1
Maag, D.2
Arnold, J.J.3
Zhong, W.4
Lau, J.Y.5
Hong, Z.6
Andino, R.7
Cameron, C.E.8
-
8
-
-
0035811016
-
RNA virus error catastrophe: Direct molecular test by using ribavirin
-
S. Crotty, C.E. Cameron, and R. Andino RNA virus error catastrophe: direct molecular test by using ribavirin Proc. Natl. Acad. Sci. U.S.A. 98 2001 6895 6900
-
(2001)
Proc. Natl. Acad. Sci. U.S.A.
, vol.98
, pp. 6895-6900
-
-
Crotty, S.1
Cameron, C.E.2
Andino, R.3
-
9
-
-
0021844137
-
A phase I and pharmacokinetic study of dihydro-5-azacytidine (NSC 264880)
-
G.A. Curt, J.A. Kelley, R.L. Fine, P.N. Huguenin, J.S. Roth, G. Batist, J. Jenkins, and J.M. Collins A phase I and pharmacokinetic study of dihydro-5-azacytidine (NSC 264880) Cancer Res. 45 1985 3359 3363
-
(1985)
Cancer Res.
, vol.45
, pp. 3359-3363
-
-
Curt, G.A.1
Kelley, J.A.2
Fine, R.L.3
Huguenin, P.N.4
Roth, J.S.5
Batist, G.6
Jenkins, J.7
Collins, J.M.8
-
10
-
-
0038621386
-
Stealth nucleosides: Mode of action and potential use in the treatment of viral diseases
-
R. Daifuku Stealth nucleosides: mode of action and potential use in the treatment of viral diseases BioDrugs 17 2003 169 177
-
(2003)
BioDrugs
, vol.17
, pp. 169-177
-
-
Daifuku, R.1
-
11
-
-
0027222068
-
Viral quasispecies
-
M. Eigen Viral quasispecies Sci. Am. 269 1993 42 49
-
(1993)
Sci. Am.
, vol.269
, pp. 42-49
-
-
Eigen, M.1
-
12
-
-
0035968250
-
Insights into the molecular mechanism of mitochondrial toxicity by AIDS drugs
-
J.Y. Feng, A.A. Johnson, K.A. Johnson, and K.S. Anderson Insights into the molecular mechanism of mitochondrial toxicity by AIDS drugs J. Biol. Chem. 276 2001 23832 23837
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 23832-23837
-
-
Feng, J.Y.1
Johnson, A.A.2
Johnson, K.A.3
Anderson, K.S.4
-
13
-
-
0037223513
-
Mutation rate and the efficacy of antimicrobial drug treatment
-
P.J. Gerrish, and J.G. Garcia-Lerma Mutation rate and the efficacy of antimicrobial drug treatment Lancet Infect. Dis. 3 2003 28 32
-
(2003)
Lancet Infect. Dis.
, vol.3
, pp. 28-32
-
-
Gerrish, P.J.1
Garcia-Lerma, J.G.2
-
14
-
-
0035798566
-
Toxicity of antiviral nucleoside analogs and the human mitochondrial DNA polymerase
-
A.A. Johnson, A.S. Ray, J. Hanes, Z. Suo, J.M. Colacino, K.S. Anderson, and K.A. Johnson Toxicity of antiviral nucleoside analogs and the human mitochondrial DNA polymerase J. Biol. Chem. 276 2001 40847 40857
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 40847-40857
-
-
Johnson, A.A.1
Ray, A.S.2
Hanes, J.3
Suo, Z.4
Colacino, J.M.5
Anderson, K.S.6
Johnson, K.A.7
-
15
-
-
0035173377
-
Human immunodeficiency virus reverse transcriptase and protease sequence database: An expanded data model integrating natural language text and sequence analysis programs
-
R. Kantor, R. Machekano, M.J. Gonzales, K. Dupnik, J.M. Schapiro, and R.W. Shafer Human immunodeficiency virus reverse transcriptase and protease sequence database: an expanded data model integrating natural language text and sequence analysis programs Nucleic Acids Res. 29 2001 296 299
-
(2001)
Nucleic Acids Res.
, vol.29
, pp. 296-299
-
-
Kantor, R.1
MacHekano, R.2
Gonzales, M.J.3
Dupnik, K.4
Schapiro, J.M.5
Shafer, R.W.6
-
16
-
-
0028959324
-
Biochemical pharmacology and DNA methylation studies of arabinosyl 5-azacytidine and 5,6-dihydro-5-azacytidine in two human leukemia cell lines PER-145 and PER-163
-
U.R. Kees, and V.I. Avramis Biochemical pharmacology and DNA methylation studies of arabinosyl 5-azacytidine and 5,6-dihydro-5-azacytidine in two human leukemia cell lines PER-145 and PER-163 Anticancer Drugs 6 1995 303 310
-
(1995)
Anticancer Drugs
, vol.6
, pp. 303-310
-
-
Kees, U.R.1
Avramis, V.I.2
-
17
-
-
0025138304
-
Susceptibilities of zidovudine-susceptible and -resistant human immunodeficiency virus isolates to antiviral agents determined by using a quantitative plaque reduction assay
-
B.A. Larder, B. Chesebro, and D.D. Richman Susceptibilities of zidovudine-susceptible and -resistant human immunodeficiency virus isolates to antiviral agents determined by using a quantitative plaque reduction assay Antimicrob. Agents Chemother. 34 1990 436 441
-
(1990)
Antimicrob. Agents Chemother.
, vol.34
, pp. 436-441
-
-
Larder, B.A.1
Chesebro, B.2
Richman, D.D.3
-
18
-
-
0026042638
-
Zidovudine-resistant human immunodeficiency virus selected by passage in cell culture
-
B.A. Larder, K.E. Coates, and S.D. Kemp Zidovudine-resistant human immunodeficiency virus selected by passage in cell culture J. Virol. 65 1991 5232 5236
-
(1991)
J. Virol.
, vol.65
, pp. 5232-5236
-
-
Larder, B.A.1
Coates, K.E.2
Kemp, S.D.3
-
19
-
-
0033573932
-
Lethal mutagenesis of HIV with mutagenic nucleoside analogs
-
L.A. Loeb, J.M. Essigmann, F. Kazazi, J. Zhang, K.D. Rose, and J.I. Mullins Lethal mutagenesis of HIV with mutagenic nucleoside analogs Proc. Natl. Acad. Sci. U.S.A. 96 1999 1492 1497
-
(1999)
Proc. Natl. Acad. Sci. U.S.A.
, vol.96
, pp. 1492-1497
-
-
Loeb, L.A.1
Essigmann, J.M.2
Kazazi, F.3
Zhang, J.4
Rose, K.D.5
Mullins, J.I.6
-
21
-
-
20444429765
-
Mechanism of action of a novel viral mutagenic covert nucleotide: Molecular interactions with HIV-1 reverse transcriptase and host cell DNA polymerases
-
Murakami, E., Basavapathruni, A., Bradley, W., Anderson, K.S., 2005. Mechanism of action of a novel viral mutagenic covert nucleotide: molecular interactions with HIV-1 reverse transcriptase and host cell DNA polymerases. Antiviral Res.
-
(2005)
Antiviral Res.
-
-
Murakami, E.1
Basavapathruni, A.2
Bradley, W.3
Anderson, K.S.4
-
22
-
-
0024974481
-
Error thresholds of replication in finite populations mutation frequencies and the onset of Muller's ratchet
-
M. Nowak, and P. Schuster Error thresholds of replication in finite populations mutation frequencies and the onset of Muller's ratchet J. Theor. Biol. 137 1989 375 395
-
(1989)
J. Theor. Biol.
, vol.137
, pp. 375-395
-
-
Nowak, M.1
Schuster, P.2
-
23
-
-
0033780046
-
Human immunodeficiency virus type 1 spinoculation enhances infection through virus binding
-
U. O'Doherty, W.J. Swiggard, and M.H. Malim Human immunodeficiency virus type 1 spinoculation enhances infection through virus binding J. Virol. 74 2000 10074 10080
-
(2000)
J. Virol.
, vol.74
, pp. 10074-10080
-
-
O'Doherty, U.1
Swiggard, W.J.2
Malim, M.H.3
-
24
-
-
0017673058
-
A quantitative assay of mutation induction at the hypoxanthine-guanine phosphoribosyl transferase locus in Chinese hamster ovary cells (CHO/HGPRT system): Development and definition of the system
-
J.P. O'Neill, P.A. Brimer, R. Machanoff, G.P. Hirsch, and A.W. Hsie A quantitative assay of mutation induction at the hypoxanthine-guanine phosphoribosyl transferase locus in Chinese hamster ovary cells (CHO/HGPRT system): development and definition of the system Mutat. Res. 45 1977 91 101
-
(1977)
Mutat. Res.
, vol.45
, pp. 91-101
-
-
O'Neill, J.P.1
Brimer, P.A.2
MacHanoff, R.3
Hirsch, G.P.4
Hsie, A.W.5
-
25
-
-
0017718690
-
Chemical mutagenesis of mammalian cells can be quantified
-
J.P. O'Neill, and A.W. Hsie Chemical mutagenesis of mammalian cells can be quantified Nature 269 1977 815 817
-
(1977)
Nature
, vol.269
, pp. 815-817
-
-
O'Neill, J.P.1
Hsie, A.W.2
-
26
-
-
0034813056
-
Efficient virus extinction by combinations of a mutagen and antiviral inhibitors
-
N. Pariente, S. Sierra, P.R. Lowenstein, and E. Domingo Efficient virus extinction by combinations of a mutagen and antiviral inhibitors J. Virol. 75 2001 9723 9730
-
(2001)
J. Virol.
, vol.75
, pp. 9723-9730
-
-
Pariente, N.1
Sierra, S.2
Lowenstein, P.R.3
Domingo, E.4
-
27
-
-
0024267430
-
Fidelity of HIV-1 reverse transcriptase
-
B.D. Preston, B.J. Poiesz, and L.A. Loeb Fidelity of HIV-1 reverse transcriptase Science 242 1988 1168 1171
-
(1988)
Science
, vol.242
, pp. 1168-1171
-
-
Preston, B.D.1
Poiesz, B.J.2
Loeb, L.A.3
-
28
-
-
0024273119
-
The accuracy of reverse transcriptase from HIV-1
-
J.D. Roberts, K. Bebenek, and T.A. Kunkel The accuracy of reverse transcriptase from HIV-1 Science 242 1988 1171 1173
-
(1988)
Science
, vol.242
, pp. 1171-1173
-
-
Roberts, J.D.1
Bebenek, K.2
Kunkel, T.A.3
-
29
-
-
0032522949
-
Dihydro-5-azacytidine and cisplatin in the treatment of malignant mesothelioma: A phase II study by the cancer and leukemia group B
-
B.L. Samuels, J.E. Herndon II, D.C. Harmon, R. Carey, J. Aisner, J.M. Corson, Y. Suzuki, M.R. Green, and N.J. Vogelzang Dihydro-5-azacytidine and cisplatin in the treatment of malignant mesothelioma: a phase II study by the cancer and leukemia group B Cancer 82 1998 1578 1584
-
(1998)
Cancer
, vol.82
, pp. 1578-1584
-
-
Samuels, B.L.1
Herndon II, J.E.2
Harmon, D.C.3
Carey, R.4
Aisner, J.5
Corson, J.M.6
Suzuki, Y.7
Green, M.R.8
Vogelzang, N.J.9
-
30
-
-
0032830814
-
Genotoxicity of 3′-azido-3′-deoxythymidine in the human lymphoblastoid cell line, TK6: Relationships between DNA incorporation, mutant frequency, and spectrum of deletion mutations in HPRT
-
H.E. Sussman, O.A. Olivero, Q. Meng, S.M. Pietras, M.C. Poirie, J.P. O'Neill, B.A. Finette, M.J. Bauer, and V.E. Walker Genotoxicity of 3′-azido-3′-deoxythymidine in the human lymphoblastoid cell line, TK6: relationships between DNA incorporation, mutant frequency, and spectrum of deletion mutations in HPRT Mutat. Res. 429 1999 249 259
-
(1999)
Mutat. Res.
, vol.429
, pp. 249-259
-
-
Sussman, H.E.1
Olivero, O.A.2
Meng, Q.3
Pietras, S.M.4
Poirie, M.C.5
O'Neill, J.P.6
Finette, B.A.7
Bauer, M.J.8
Walker, V.E.9
-
31
-
-
0032565577
-
Mutagenicity and repair of oxidative DNA damage: Insights from studies using defined lesions
-
D. Wang, D.A. Kreutzer, and J.M. Essigmann Mutagenicity and repair of oxidative DNA damage: insights from studies using defined lesions Mutat. Res. 400 1998 99 115
-
(1998)
Mutat. Res.
, vol.400
, pp. 99-115
-
-
Wang, D.1
Kreutzer, D.A.2
Essigmann, J.M.3
|